Cheap flights from Houston to Sao Paulo from $354

The cheapest month to fly to Sao Paulo from Houston is in April. Flight prices, which tend to average around $1,114, are often lower during this time because this is during the off-season. If you don’t want to visit Sao Paulo in April, then you should wait until November to fly from Houston, when ticket prices are also cheap, with an average price of $1,218.

In the evening is the cheapest time of day to fly from Houston to Sao Paulo when you can find flight prices for as low as $1,425. Flying to Sao Paulo in the evening is an ideal time because this is during off-peak travel hours. Flights to Sao Paulo are more costly in the afternoon, with an average ticket price of $1,498. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Houston George Bush Intcntl to Sao Paulo Guarulhos Intl for the best Houston - Sao Paulo flight prices

There are 3 cabin classes available to choose from on Houston to Sao Paulo flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

The number of flights available between Houston and Sao Paulo is 2 per day as of November 2026. The most frequent departure time is 9:00PM, with 100% of daily flights leaving in the evening.

As of November 2026, 14 flights take off from Houston and land in Sao Paulo each week. The most common flight departure day for this route is Mon, with 14% of weekly flights taking off on this day.