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Cheap flights from Houston to Santiago de los Caballeros from $227

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Santiago de los Caballeros departing on 5/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Houston to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
10:36 am - 9:54 am
IAH
-
STI
22h 18m
1 stop
Frontier Logo
11:09 am - 9:41 am
STI
-
IAH
23h 32m
1 stop
$405Frontier
Wed, Jun 17 - Sun, Jun 21
Multiple Airlines Logo
6:00 am - 2:45 pm
IAH
-
STI
7h 45m
1 stop
Multiple Airlines Logo
11:14 am - 9:38 am
STI
-
IAH
23h 24m
1 stop
$546Multiple Airlines
Sat, Jun 27 - Thu, Jul 9
Multiple Airlines Logo
10:36 am - 9:54 am
IAH
-
STI
22h 18m
1 stop
Multiple Airlines Logo
6:00 am - 5:25 pm
STI
-
IAH
12h 25m
1 stop
$558Multiple Airlines
Wed, Jun 10 - Wed, Jun 17
Multiple Airlines Logo
8:29 am - 2:12 pm
IAH
-
STI
28h 43m
1 stop
Multiple Airlines Logo
4:15 pm - 7:34 am
STI
-
IAH
16h 19m
2 stops
$559Multiple Airlines
Fri, May 22 - Fri, May 29
Multiple Airlines Logo
8:29 am - 2:12 pm
IAH
-
STI
28h 43m
1 stop
Multiple Airlines Logo
4:15 pm - 3:03 pm
STI
-
IAH
23h 48m
1 stop
$578Multiple Airlines
Fri, May 22 - Fri, May 29
Spirit Airlines Logo
6:00 am - 2:45 pm
IAH
-
STI
7h 45m
1 stop
Spirit Airlines Logo
4:20 pm - 8:46 am
STI
-
IAH
17h 26m
1 stop
$608Spirit Airlines
Sat, Jun 27 - Fri, Jul 10
Delta Logo
5:40 am - 1:59 am
IAH
-
STI
19h 19m
2 stops
Delta Logo
8:59 pm - 1:38 pm
STI
-
IAH
17h 39m
2 stops
$615Delta
Wed, Jun 10 - Wed, Jun 17
American Airlines Logo
6:03 am - 9:12 pm
HOU
-
STI
14h 09m
2 stops
American Airlines Logo
3:39 pm - 8:57 am
STI
-
HOU
18h 18m
2 stops
$676American Airlines
Wed, Jun 10 - Wed, Jun 17
American Airlines Logo
6:03 am - 9:13 pm
HOU
-
STI
14h 10m
2 stops
American Airlines Logo
7:03 am - 6:09 pm
STI
-
HOU
12h 06m
2 stops
$705American Airlines
Sat, May 23 - Thu, May 28
Delta Logo
6:00 am - 7:33 pm
HOU
-
STI
12h 33m
2 stops
Delta Logo
6:00 am - 9:43 pm
STI
-
HOU
16h 43m
2 stops
$889Delta
Sun, Jun 7 - Sat, Jul 4

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Spirit Airlines flights from Houston to Santiago de los Caballeros

Our best Spirit Airlines deals on Houston to Santiago de los Caballeros flight tickets
Spirit Airlines
Jun 27
IAH6:00 amHouston George Bush Intcntl
7h 45m
1 stop
STI2:45 pmSantiago de los Caballeros
Jul 10
STI4:20 pmSantiago de los Caballeros
17h 26m
1 stop
IAH8:46 amHouston George Bush Intcntl
$608
Spirit Airlines
May 22
IAH8:28 amHouston George Bush Intcntl
28h 44m
3 stops
STI2:12 pmSantiago de los Caballeros
May 29
STI4:15 pmSantiago de los Caballeros
8h 21m
1 stop
IAH11:36 pmHouston George Bush Intcntl
$671
Spirit Airlines
Jul 18
IAH6:00 amHouston George Bush Intcntl
8h 15m
1 stop
STI3:15 pmSantiago de los Caballeros
Jul 24
STI4:20 pmSantiago de los Caballeros
7h 23m
1 stop
IAH10:43 pmHouston George Bush Intcntl
$672

JetBlue flights from Houston to Santiago de los Caballeros

Our best JetBlue deals on Houston to Santiago de los Caballeros flight tickets
JetBlue
May 23
IAH5:44 pmHouston George Bush Intcntl
30h 15m
1 stop
STI12:59 amSantiago de los Caballeros
May 27
STI7:21 pmSantiago de los Caballeros
22h 23m
2 stops
IAH4:44 pmHouston George Bush Intcntl
$629
JetBlue
May 23
IAH5:44 pmHouston George Bush Intcntl
30h 15m
1 stop
STI12:59 amSantiago de los Caballeros
May 28
STI8:14 amSantiago de los Caballeros
9h 30m
1 stop
IAH4:44 pmHouston George Bush Intcntl
$687
JetBlue
May 27
IAH11:56 amHouston George Bush Intcntl
12h 03m
1 stop
STI12:59 amSantiago de los Caballeros
May 30
STI8:14 amSantiago de los Caballeros
9h 30m
1 stop
IAH4:44 pmHouston George Bush Intcntl
$724

momondo Fare Finder

 
Customize your flight search to find flights from Houston to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 1, 2026.
Use the filters below to find and compare flights from Houston to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Wed 6/17

10:36 am-9:54 am

1 stop22h 18m

Santiago de los Caballeros

Sun 6/21

11:09 am-9:41 am

1 stop23h 32m

$405

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Sat 6/27

6:00 am-2:45 pm

1 stop7h 45m

Santiago de los Caballeros

Thu 7/9

11:14 am-9:38 am

1 stop23h 24m

$546

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Wed 6/10

10:36 am-9:54 am

1 stop22h 18m

Santiago de los Caballeros

Wed 6/17

6:00 am-5:25 pm

1 stop12h 25m

$558

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Fri 5/22

8:29 am-2:12 pm

1 stop28h 43m

Santiago de los Caballeros

Fri 5/29

4:15 pm-7:34 am

2 stops16h 19m

$559

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Fri 5/22

8:29 am-2:12 pm

1 stop28h 43m

Santiago de los Caballeros

Fri 5/29

4:15 pm-3:03 pm

1 stop23h 48m

$578
Quickest round-trip

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Sat 6/27

6:00 am-2:45 pm

1 stop7h 45m

Santiago de los Caballeros

Fri 7/10

4:20 pm-8:46 am

1 stop17h 26m

$608

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Wed 6/10

5:40 am-1:59 am

2 stops19h 19m

Santiago de los Caballeros

Wed 6/17

8:59 pm-1:38 pm

2 stops17h 39m

$615

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Wed 6/10

6:03 am-9:12 pm

2 stops14h 09m

Santiago de los Caballeros

Wed 6/17

3:39 pm-8:57 am

2 stops18h 18m

$676

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Sat 5/23

6:03 am-9:13 pm

2 stops14h 10m

Santiago de los Caballeros

Thu 5/28

7:03 am-6:09 pm

2 stops12h 06m

$705

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Sun 6/7

6:00 am-7:33 pm

2 stops12h 33m

Santiago de los Caballeros

Sat 7/4

6:00 am-9:43 pm

2 stops16h 43m

$889

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Houston to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Houston and Santiago de los Caballeros?

What is the cheapest month to fly to Santiago de los Caballeros?

The cheapest month to fly to Santiago de los Caballeros from Houston is in December. Flight prices, which tend to average around $228, are often lower during this time because this is during the off-season. If you aren’t able to travel to Santiago de los Caballeros during the month of December, then flying in March is also cheap. Prices for this month can be found on momondo for an average of $265.

Cheap Houston to Santiago de los Caballeros flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Santiago de los Caballeros

Fastest flight time

7h 27m

Direct flights

None
The fastest flight from Houston to Santiago de los Caballeros takes 7h 27m
There are no direct flights from Houston to Santiago de los Caballeros. There are no popular flight routes from Houston to Santiago de los Caballeros.
Search flight deals

Frequently asked questions about flying from Houston to Santiago de los Caballeros

  • How far is Houston to Santiago de los Caballeros by plane?

    Santiago de los Caballeros is 1699.3 mi away from Houston. Flights usually cover this in 7h 27m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Houston to Santiago de los Caballeros Airport?

    Prices for flights from Houston to Santiago de los Caballeros Airport were last updated today.

  • How many operators does momondo search for flights from Houston to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Houston to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The necessary travel and health documents for your Santiago de los Caballeros Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Houston to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $290Free CancellationRating
6.3
8,637 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $514Free CancellationRating
7.1
11,683 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Santiago de los Caballeros?

It is quick and easy to find Houston to Santiago de los Caballeros flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago de los Caballeros that suits you.

Can I find flights from Houston to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Houston to Santiago de los Caballeros flights to just show those with flexible booking policies.

How can momondo help me find flights from Houston to Santiago de los Caballeros?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santiago de los Caballeros from Houston.

I’m not ready to book a flight from Houston to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Houston to Santiago de los Caballeros flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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