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Cheap flights from Houston to Santiago de los Caballeros from $257

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Santiago de los Caballeros departing on 8/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Houston to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
6:15 am - 1:27 pm
IAH
-
STI
6h 12m
1 stop
JetBlue Logo
3:30 pm - 9:55 pm
STI
-
IAH
7h 25m
1 stop
$543JetBlue
Tue, Sep 15 - Tue, Sep 22
JetBlue Logo
6:15 am - 1:27 pm
IAH
-
STI
6h 12m
1 stop
JetBlue Logo
3:30 pm - 9:55 pm
STI
-
IAH
7h 25m
1 stop
$548JetBlue
Tue, Sep 15 - Tue, Sep 22
JetBlue Logo
6:15 am - 1:27 pm
IAH
-
STI
6h 12m
1 stop
JetBlue Logo
3:30 pm - 9:55 pm
STI
-
IAH
7h 25m
1 stop
$553JetBlue
Thu, Sep 10 - Thu, Sep 24
JetBlue Logo
6:15 am - 1:27 pm
IAH
-
STI
6h 12m
1 stop
JetBlue Logo
3:30 pm - 9:55 pm
STI
-
IAH
7h 25m
1 stop
$553JetBlue
Tue, Sep 15 - Tue, Sep 22
American Airlines Logo
5:32 am - 2:15 pm
IAH
-
STI
7h 43m
1 stop
American Airlines Logo
3:16 pm - 11:47 pm
STI
-
IAH
9h 31m
1 stop
$620American Airlines
Fri, Oct 2 - Tue, Oct 13
American Airlines Logo
7:27 am - 2:12 pm
IAH
-
STI
5h 45m
1 stop
American Airlines Logo
3:16 pm - 11:47 pm
STI
-
IAH
9h 31m
1 stop
$620American Airlines
Tue, Oct 13 - Tue, Oct 20
American Airlines Logo
5:32 am - 2:15 pm
IAH
-
STI
7h 43m
1 stop
American Airlines Logo
3:16 pm - 11:47 pm
STI
-
IAH
9h 31m
1 stop
$620American Airlines
Fri, Sep 18 - Tue, Oct 6
Delta Logo
6:49 pm - 12:26 pm
IAH
-
STI
16h 37m
2 stops
Delta Logo
7:30 pm - 3:54 pm
STI
-
IAH
21h 24m
2 stops
$625Delta
Tue, Sep 15 - Tue, Sep 22
Delta Logo
5:26 pm - 12:26 pm
HOU
-
STI
18h 00m
2 stops
Delta Logo
7:30 pm - 4:30 pm
STI
-
HOU
22h 00m
2 stops
$625Delta
Tue, Sep 15 - Tue, Sep 22
United Airlines Logo
9:57 am - 10:52 pm
IAH
-
STI
11h 55m
1 stop
United Airlines Logo
2:07 pm - 11:30 pm
STI
-
IAH
10h 23m
1 stop
$630United Airlines
Mon, Sep 7 - Mon, Sep 14

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American Airlines flights from Houston to Santiago de los Caballeros

Our best American Airlines deals on Houston to Santiago de los Caballeros flight tickets
American Airlines
Oct 2
IAH5:32 amHouston George Bush Intcntl
7h 43m
1 stop
STI2:15 pmSantiago de los Caballeros
Oct 13
STI3:16 pmSantiago de los Caballeros
9h 31m
1 stop
IAH11:47 pmHouston George Bush Intcntl
$620
American Airlines
Oct 1
HOU8:18 pmHouston Hobby
16h 57m
2 stops
STI2:15 pmSantiago de los Caballeros
Oct 6
STI3:16 pmSantiago de los Caballeros
9h 33m
2 stops
HOU11:49 pmHouston Hobby
$625
American Airlines
Sep 17
IAH5:50 pmHouston George Bush Intcntl
19h 25m
1 stop
STI2:15 pmSantiago de los Caballeros
Sep 23
STI3:15 pmSantiago de los Caballeros
7h 44m
1 stop
IAH9:59 pmHouston George Bush Intcntl
$634

Delta flights from Houston to Santiago de los Caballeros

Our best Delta deals on Houston to Santiago de los Caballeros flight tickets
Delta
Nov 1
IAH5:35 amHouston George Bush Intcntl
10h 58m
2 stops
STI6:33 pmSantiago de los Caballeros
Nov 18
STI6:40 amSantiago de los Caballeros
19h 19m
2 stops
IAH11:59 pmHouston George Bush Intcntl
$635
Delta
Sep 18
IAH6:49 pmHouston George Bush Intcntl
16h 37m
2 stops
STI12:26 pmSantiago de los Caballeros
Sep 24
STI7:30 pmSantiago de los Caballeros
16h 35m
2 stops
IAH11:05 amHouston George Bush Intcntl
$645
Delta
Oct 31
HOU5:28 pmHouston Hobby
19h 05m
2 stops
STI1:33 pmSantiago de los Caballeros
Nov 17
STI6:40 amSantiago de los Caballeros
18h 33m
2 stops
HOU11:13 pmHouston Hobby
$655

momondo Fare Finder

 
Customize your flight search to find flights from Houston to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 29, 2026.
Use the filters below to find and compare flights from Houston to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Tue 9/15

6:15 am-1:27 pm

1 stop6h 12m

Santiago de los Caballeros

Tue 9/22

3:30 pm-9:55 pm

1 stop7h 25m

$543

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Tue 9/15

6:15 am-1:27 pm

1 stop6h 12m

Santiago de los Caballeros

Tue 9/22

3:30 pm-9:55 pm

1 stop7h 25m

$548

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Thu 9/10

6:15 am-1:27 pm

1 stop6h 12m

Santiago de los Caballeros

Thu 9/24

3:30 pm-9:55 pm

1 stop7h 25m

$553

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Tue 9/15

6:15 am-1:27 pm

1 stop6h 12m

Santiago de los Caballeros

Tue 9/22

3:30 pm-9:55 pm

1 stop7h 25m

$553

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Fri 10/2

5:32 am-2:15 pm

1 stop7h 43m

Santiago de los Caballeros

Tue 10/13

3:16 pm-11:47 pm

1 stop9h 31m

$620

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Tue 10/13

7:27 am-2:12 pm

1 stop5h 45m

Santiago de los Caballeros

Tue 10/20

3:16 pm-11:47 pm

1 stop9h 31m

$620

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Fri 9/18

5:32 am-2:15 pm

1 stop7h 43m

Santiago de los Caballeros

Tue 10/6

3:16 pm-11:47 pm

1 stop9h 31m

$620

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Tue 9/15

6:49 pm-12:26 pm

2 stops16h 37m

Santiago de los Caballeros

Tue 9/22

7:30 pm-3:54 pm

2 stops21h 24m

$625

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Tue 9/15

5:26 pm-12:26 pm

2 stops18h 00m

Santiago de los Caballeros

Tue 9/22

7:30 pm-4:30 pm

2 stops22h 00m

$625

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Mon 9/7

9:57 am-10:52 pm

1 stop11h 55m

Santiago de los Caballeros

Mon 9/14

2:07 pm-11:30 pm

1 stop10h 23m

$630

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Houston to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Houston and Santiago de los Caballeros?

Prices are currently high for flights on this route.

Typical prices usually range from $267 to $501.
The lowest price recently found on this route was $543.

What is the cheapest month to fly to Santiago de los Caballeros?

The cheapest month to fly to Santiago de los Caballeros from Houston is in October. Flight prices, which tend to average around $329, are often lower during this time because this is during the off-season. If you aren’t able to travel to Santiago de los Caballeros during the month of October, then flying in March is also cheap. Prices for this month can be found on momondo for an average of $471.

Cheap Houston to Santiago de los Caballeros flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Santiago de los Caballeros

Fastest flight time

6h 12m

Direct flights

None
The fastest flight from Houston to Santiago de los Caballeros takes 6h 12m
There are no direct flights from Houston to Santiago de los Caballeros. There are no popular flight routes from Houston to Santiago de los Caballeros.
Search flight deals

Frequently asked questions about flying from Houston to Santiago de los Caballeros

  • How far is Houston to Santiago de los Caballeros by plane?

    Santiago de los Caballeros is 1699.3 mi away from Houston. Flights usually cover this in 6h 12m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Houston to Santiago de los Caballeros Airport?

    Prices for flights from Houston to Santiago de los Caballeros Airport were last updated today.

  • How many operators does momondo search for flights from Houston to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Houston to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The necessary travel and health documents for your Santiago de los Caballeros Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Houston to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $244Free CancellationRating
7.1
3,023 reviews
Search JetBlue flights
American AirlinesPriceFrom $514Free CancellationRating
7.1
11,839 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Santiago de los Caballeros?

It is quick and easy to find Houston to Santiago de los Caballeros flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago de los Caballeros that suits you.

Can I find flights from Houston to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Houston to Santiago de los Caballeros flights to just show those with flexible booking policies.

How can momondo help me find flights from Houston to Santiago de los Caballeros?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santiago de los Caballeros from Houston.

I’m not ready to book a flight from Houston to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Houston to Santiago de los Caballeros flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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