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Cheap flights from Houston to Santiago de los Caballeros from $158

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Santiago de los Caballeros departing on 8/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Houston to Santiago de los Caballeros

Cheap round-trip flights

Spirit Airlines Logo
7:31 pm - 11:05 amIAH-STI
14h 34m1 stop
Spirit Airlines Logo
12:10 pm - 7:26 pmSTI-IAH
8h 16m1 stop
$298Spirit Airlines
Find Deal
Tue, Oct 7 - Wed, Oct 22
Spirit Airlines Logo
7:31 pm - 11:03 amIAH-STI
14h 32m1 stop
Spirit Airlines Logo
12:10 pm - 11:56 pmSTI-IAH
12h 46m1 stop
$302Spirit Airlines
Find Deal
Sat, Sep 6 - Tue, Sep 9
Spirit Airlines Logo
7:31 pm - 11:03 amIAH-STI
14h 32m1 stop
Spirit Airlines Logo
12:10 pm - 10:42 pmSTI-IAH
11h 32m1 stop
$321Spirit Airlines
Find Deal
Wed, Sep 17 - Wed, Sep 24
Spirit Airlines Logo
5:30 am - 9:15 amIAH-STI
26h 45m1 stop
Spirit Airlines Logo
12:10 pm - 10:42 pmSTI-IAH
11h 32m1 stop
$329Spirit Airlines
Find Deal
Tue, Sep 2 - Tue, Sep 9
Logo
8:56 pm - 11:05 amIAH-STI
13h 09m2 stops
Logo
12:10 pm - 7:26 pmSTI-IAH
8h 16m1 stop
$407
Find Deal
Tue, Oct 7 - Tue, Oct 21
Frontier Logo
8:56 pm - 12:55 pmIAH-STI
14h 59m2 stops
Frontier Logo
2:15 pm - 9:05 amSTI-IAH
19h 50m2 stops
$494Frontier
Find Deal
Wed, Oct 8 - Thu, Oct 23
Delta Logo
6:34 pm - 12:40 pmHOU-STI
17h 06m2 stops
Delta Logo
8:40 pm - 12:18 pmSTI-HOU
16h 38m2 stops
$519Delta
Find Deal
Wed, Sep 10 - Wed, Sep 17
Delta Logo
6:09 pm - 12:03 pmIAH-STI
16h 54m2 stops
Delta Logo
8:31 pm - 11:28 amSTI-IAH
15h 57m1 stop
$519Delta
Find Deal
Wed, Oct 8 - Thu, Oct 23
American Airlines Logo
2:33 pm - 12:27 pmHOU-STI
20h 54m2 stops
American Airlines Logo
1:29 pm - 8:34 amSTI-HOU
20h 05m2 stops
$539American Airlines
Find Deal
Sat, Sep 6 - Tue, Sep 9
American Airlines Logo
2:52 pm - 12:27 pmIAH-STI
20h 35m2 stops
American Airlines Logo
1:29 pm - 9:22 amSTI-IAH
20h 53m2 stops
$539American Airlines
Find Deal
Sat, Sep 6 - Tue, Sep 9

Spirit Airlines flights from Houston to Santiago de los Caballeros

Our best Spirit Airlines deals on Houston to Santiago de los Caballeros flight tickets
Spirit Airlines
Oct 7
IAH7:31 pmHouston George Bush Intcntl
14h 34m
1 stop
STI11:05 amSantiago de los Caballeros
Oct 22
STI12:10 pmSantiago de los Caballeros
8h 16m
1 stop
IAH7:26 pmHouston George Bush Intcntl
$298
Find similar
Spirit Airlines
Sep 6
IAH7:31 pmHouston George Bush Intcntl
14h 32m
1 stop
STI11:03 amSantiago de los Caballeros
Sep 9
STI12:10 pmSantiago de los Caballeros
12h 46m
1 stop
IAH11:56 pmHouston George Bush Intcntl
$302
Find similar
Spirit Airlines
Sep 17
IAH7:31 pmHouston George Bush Intcntl
14h 32m
1 stop
STI11:03 amSantiago de los Caballeros
Sep 24
STI12:10 pmSantiago de los Caballeros
11h 32m
1 stop
IAH10:42 pmHouston George Bush Intcntl
$321
Find similar

Frontier flights from Houston to Santiago de los Caballeros

Our best Frontier deals on Houston to Santiago de los Caballeros flight tickets
Frontier
Aug 14
IAH8:56 pmHouston George Bush Intcntl
14h 55m
2 stops
STI12:51 pmSantiago de los Caballeros
Aug 21
STI1:26 pmSantiago de los Caballeros
27h 19m
2 stops
IAH3:45 pmHouston George Bush Intcntl
$493
Find similar
Frontier
Oct 8
IAH8:56 pmHouston George Bush Intcntl
14h 59m
2 stops
STI12:55 pmSantiago de los Caballeros
Oct 23
STI2:15 pmSantiago de los Caballeros
19h 50m
2 stops
IAH9:05 amHouston George Bush Intcntl
$494
Find similar
Frontier
Aug 14
IAH8:56 pmHouston George Bush Intcntl
14h 55m
2 stops
STI12:51 pmSantiago de los Caballeros
Aug 21
STI1:26 pmSantiago de los Caballeros
27h 19m
2 stops
IAH3:45 pmHouston George Bush Intcntl
$524
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Houston to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 6, 2025.
Use the filters below to find and compare flights from Houston to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Tue 10/7

7:31 pm-11:05 am

1 stop14h 34m

Santiago de los Caballeros

Wed 10/22

12:10 pm-7:26 pm

1 stop8h 16m

$298

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Sat 9/6

7:31 pm-11:03 am

1 stop14h 32m

Santiago de los Caballeros

Tue 9/9

12:10 pm-11:56 pm

1 stop12h 46m

$302

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Wed 9/17

7:31 pm-11:03 am

1 stop14h 32m

Santiago de los Caballeros

Wed 9/24

12:10 pm-10:42 pm

1 stop11h 32m

$321

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Tue 9/2

5:30 am-9:15 am

1 stop26h 45m

Santiago de los Caballeros

Tue 9/9

12:10 pm-10:42 pm

1 stop11h 32m

$329

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Tue 10/7

8:56 pm-11:05 am

2 stops13h 09m

Santiago de los Caballeros

Tue 10/21

12:10 pm-7:26 pm

1 stop8h 16m

$407

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Wed 10/8

8:56 pm-12:55 pm

2 stops14h 59m

Santiago de los Caballeros

Thu 10/23

2:15 pm-9:05 am

2 stops19h 50m

$494

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Wed 9/10

6:34 pm-12:40 pm

2 stops17h 06m

Santiago de los Caballeros

Wed 9/17

8:40 pm-12:18 pm

2 stops16h 38m

$519

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Wed 10/8

6:09 pm-12:03 pm

2 stops16h 54m

Santiago de los Caballeros

Thu 10/23

8:31 pm-11:28 am

1 stop15h 57m

$519

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Sat 9/6

2:33 pm-12:27 pm

2 stops20h 54m

Santiago de los Caballeros

Tue 9/9

1:29 pm-8:34 am

2 stops20h 05m

$539

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Sat 9/6

2:52 pm-12:27 pm

2 stops20h 35m

Santiago de los Caballeros

Tue 9/9

1:29 pm-9:22 am

2 stops20h 53m

$539

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Houston to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Houston and Santiago de los Caballeros?

What is the cheapest day to depart on your flight to Santiago de los Caballeros?

The cheapest day to depart from Houston to Santiago de los Caballeros is on a Thursday when prices can be found for as low as $555. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Houston to Santiago de los Caballeros for around $770.

What is the cheapest time of day to depart on your flight to Santiago de los Caballeros?

Our data shows that the cheapest Houston to Santiago de los Caballeros flights are usually those with departure times in the evening. Our users have found flights to Santiago de los Caballeros in the evening for as low as $332. At noon is when there is more demand to fly to Santiago de los Caballeros, so prices are often more expensive at around $762 per ticket.

Cheap Houston to Santiago de los Caballeros flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Santiago de los Caballeros

Best Price Found

$158

Fastest flight time

5h 12m

Direct flights

None

Airports in Santiago de los Caballeros

1 airport
The best one-way flight to Santiago de los Caballeros from Houston in the past 72 hours is $158. The best round-trip flight deal from Houston to Santiago de los Caballeros found on momondo in the last 72 hours is $298.
The fastest flight from Houston to Santiago de los Caballeros takes 5h 12m
There are no direct flights from Houston to Santiago de los Caballeros. Popular non-direct routes for this connection are Houston George Bush Intcntl Airport - Santiago de los Caballeros Airport and Houston Hobby Airport - Santiago de los Caballeros Airport.
There is 1 airport near Santiago de los Caballeros: Santiago de los Caballeros (STI)
Search flight deals

  • How far is Houston to Santiago de los Caballeros by plane?

    Santiago de los Caballeros is 1699.3 mi away from Houston. Flights usually cover this in 5h 12m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Houston to Santiago de los Caballeros Airport?

    Prices for flights from Houston to Santiago de los Caballeros Airport were last updated today.

  • How many operators does momondo search for flights from Houston to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Houston to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The necessary travel and health documents for your Santiago de los Caballeros Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Houston to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $329Free CancellationRating
6.3
8,055 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $552Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Santiago de los Caballeros?

It is quick and easy to find Houston to Santiago de los Caballeros flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago de los Caballeros that suits you.

Can I find flights from Houston to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Houston to Santiago de los Caballeros flights to just show those with flexible booking policies.

How can momondo help me find flights from Houston to Santiago de los Caballeros?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santiago de los Caballeros from Houston.

I’m not ready to book a flight from Houston to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Houston to Santiago de los Caballeros flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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