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Cheap flights from Houston to Santiago de los Caballeros from $179

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Santiago de los Caballeros departing on 8/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Houston to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
4:42 pm - 12:51 am
IAH
-
STI
6h 09m
1 stop
JetBlue Logo
6:01 am - 11:47 am
STI
-
IAH
7h 46m
1 stop
$403JetBlue
Sun, Nov 1 - Sat, Nov 7
JetBlue Logo
1:00 pm - 11:51 pm
IAH
-
STI
9h 51m
1 stop
JetBlue Logo
5:01 am - 11:47 am
STI
-
IAH
7h 46m
1 stop
$404JetBlue
Sun, Jul 12 - Tue, Jul 21
JetBlue Logo
1:00 pm - 11:51 pm
IAH
-
STI
9h 51m
1 stop
JetBlue Logo
3:51 pm - 11:02 pm
STI
-
IAH
8h 11m
1 stop
$407JetBlue
Sat, Aug 1 - Sat, Aug 8
JetBlue Logo
6:35 am - 1:27 pm
IAH
-
STI
5h 52m
1 stop
JetBlue Logo
3:49 pm - 10:07 pm
STI
-
IAH
7h 18m
1 stop
$421JetBlue
Tue, Sep 15 - Tue, Sep 22
Delta Logo
5:26 pm - 12:40 pm
HOU
-
STI
18h 14m
2 stops
Delta Logo
7:16 pm - 4:31 pm
STI
-
HOU
22h 15m
2 stops
$615Delta
Tue, Sep 15 - Tue, Sep 22
Delta Logo
2:25 pm - 12:40 pm
HOU
-
STI
21h 15m
2 stops
Delta Logo
7:16 pm - 4:31 pm
STI
-
HOU
22h 15m
2 stops
$635Delta
Mon, Sep 14 - Mon, Sep 21
American Airlines Logo
9:37 am - 8:03 pm
HOU
-
STI
9h 26m
2 stops
American Airlines Logo
3:15 pm - 11:14 am
STI
-
HOU
20h 59m
2 stops
$685American Airlines
Tue, Sep 1 - Sun, Sep 13
American Airlines Logo
6:00 am - 8:49 pm
HOU
-
STI
12h 49m
2 stops
American Airlines Logo
7:00 am - 3:54 pm
STI
-
HOU
10h 54m
2 stops
$777American Airlines
Sun, Nov 1 - Sat, Nov 7
American Airlines Logo
6:19 pm - 12:10 pm
HOU
-
STI
16h 51m
2 stops
American Airlines Logo
1:40 pm - 11:53 pm
STI
-
HOU
11h 13m
2 stops
$830American Airlines
Fri, Oct 9 - Wed, Oct 14
American Airlines Logo
6:03 am - 9:29 pm
HOU
-
STI
14h 26m
2 stops
American Airlines Logo
7:00 am - 6:19 pm
STI
-
HOU
12h 19m
2 stops
$860American Airlines
Sat, Jul 18 - Fri, Jul 24

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United Airlines flights from Houston to Santiago de los Caballeros

Our best United Airlines deals on Houston to Santiago de los Caballeros flight tickets
United Airlines
Jun 19
IAH7:55 pmHouston George Bush Intcntl
18h 17m
1 stop
STI3:12 pmSantiago de los Caballeros
Jun 21
STI6:00 amSantiago de los Caballeros
11h 58m
1 stop
IAH4:58 pmHouston George Bush Intcntl
$1,215
United Airlines
Jun 18
IAH7:55 pmHouston George Bush Intcntl
18h 17m
1 stop
STI3:12 pmSantiago de los Caballeros
Jun 21
STI6:00 amSantiago de los Caballeros
11h 58m
1 stop
IAH4:58 pmHouston George Bush Intcntl
$1,250

JetBlue flights from Houston to Santiago de los Caballeros

Our best JetBlue deals on Houston to Santiago de los Caballeros flight tickets
JetBlue
Nov 1
IAH4:42 pmHouston George Bush Intcntl
6h 09m
1 stop
STI12:51 amSantiago de los Caballeros
Nov 7
STI6:01 amSantiago de los Caballeros
7h 46m
1 stop
IAH11:47 amHouston George Bush Intcntl
$403
JetBlue
Jul 12
IAH1:00 pmHouston George Bush Intcntl
9h 51m
1 stop
STI11:51 pmSantiago de los Caballeros
Jul 21
STI5:01 amSantiago de los Caballeros
7h 46m
1 stop
IAH11:47 amHouston George Bush Intcntl
$404
JetBlue
Aug 1
IAH1:00 pmHouston George Bush Intcntl
9h 51m
1 stop
STI11:51 pmSantiago de los Caballeros
Aug 8
STI3:51 pmSantiago de los Caballeros
8h 11m
1 stop
IAH11:02 pmHouston George Bush Intcntl
$407

momondo Fare Finder

 
Customize your flight search to find flights from Houston to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 14, 2026.
Use the filters below to find and compare flights from Houston to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Sun 11/1

4:42 pm-12:51 am

1 stop6h 09m

Santiago de los Caballeros

Sat 11/7

6:01 am-11:47 am

1 stop7h 46m

$403

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Sun 7/12

1:00 pm-11:51 pm

1 stop9h 51m

Santiago de los Caballeros

Tue 7/21

5:01 am-11:47 am

1 stop7h 46m

$404

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Sat 8/1

1:00 pm-11:51 pm

1 stop9h 51m

Santiago de los Caballeros

Sat 8/8

3:51 pm-11:02 pm

1 stop8h 11m

$407
Quickest round-trip

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Tue 9/15

6:35 am-1:27 pm

1 stop5h 52m

Santiago de los Caballeros

Tue 9/22

3:49 pm-10:07 pm

1 stop7h 18m

$421

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Tue 9/15

5:26 pm-12:40 pm

2 stops18h 14m

Santiago de los Caballeros

Tue 9/22

7:16 pm-4:31 pm

2 stops22h 15m

$615

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Mon 9/14

2:25 pm-12:40 pm

2 stops21h 15m

Santiago de los Caballeros

Mon 9/21

7:16 pm-4:31 pm

2 stops22h 15m

$635

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Tue 9/1

9:37 am-8:03 pm

2 stops9h 26m

Santiago de los Caballeros

Sun 9/13

3:15 pm-11:14 am

2 stops20h 59m

$685

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Sun 11/1

6:00 am-8:49 pm

2 stops12h 49m

Santiago de los Caballeros

Sat 11/7

7:00 am-3:54 pm

2 stops10h 54m

$777

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Fri 10/9

6:19 pm-12:10 pm

2 stops16h 51m

Santiago de los Caballeros

Wed 10/14

1:40 pm-11:53 pm

2 stops11h 13m

$830

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Sat 7/18

6:03 am-9:29 pm

2 stops14h 26m

Santiago de los Caballeros

Fri 7/24

7:00 am-6:19 pm

2 stops12h 19m

$860

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Houston to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Houston and Santiago de los Caballeros?

What is the cheapest month to fly to Santiago de los Caballeros?

The cheapest month to fly to Santiago de los Caballeros from Houston is in December. Flight prices, which tend to average around $228, are often lower during this time because this is during the off-season. If you aren’t able to travel to Santiago de los Caballeros during the month of December, then flying in August is also cheap. Prices for this month can be found on momondo for an average of $244.

Cheap Houston to Santiago de los Caballeros flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Santiago de los Caballeros

Fastest flight time

5h 52m

Direct flights

None
The fastest flight from Houston to Santiago de los Caballeros takes 5h 52m
There are no direct flights from Houston to Santiago de los Caballeros. There are no popular flight routes from Houston to Santiago de los Caballeros.
Search flight deals

Frequently asked questions about flying from Houston to Santiago de los Caballeros

  • How far is Houston to Santiago de los Caballeros by plane?

    Santiago de los Caballeros is 1699.3 mi away from Houston. Flights usually cover this in 5h 52m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Houston to Santiago de los Caballeros Airport?

    Prices for flights from Houston to Santiago de los Caballeros Airport were last updated today.

  • How many operators does momondo search for flights from Houston to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Houston to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The necessary travel and health documents for your Santiago de los Caballeros Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Houston to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $514Free CancellationRating
7.1
11,648 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Santiago de los Caballeros?

It is quick and easy to find Houston to Santiago de los Caballeros flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago de los Caballeros that suits you.

Can I find flights from Houston to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Houston to Santiago de los Caballeros flights to just show those with flexible booking policies.

How can momondo help me find flights from Houston to Santiago de los Caballeros?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santiago de los Caballeros from Houston.

I’m not ready to book a flight from Houston to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Houston to Santiago de los Caballeros flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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