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Cheap flights from Houston to Santiago de los Caballeros from $157

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Santiago de los Caballeros departing on 2/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Houston to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
7:21 am - 3:35 pm
IAH
-
STI
6h 14m
1 stop
Spirit Airlines Logo
4:40 pm - 12:18 am
STI
-
IAH
9h 38m
1 stop
$295Spirit Airlines
Wed, Feb 18 - Wed, Feb 25
Spirit Airlines Logo
7:21 am - 3:35 pm
IAH
-
STI
6h 14m
1 stop
Spirit Airlines Logo
4:40 pm - 12:18 am
STI
-
IAH
9h 38m
1 stop
$311Spirit Airlines
Thu, Feb 19 - Thu, Feb 26
Multiple Airlines Logo
2:41 pm - 3:35 pm
IAH
-
STI
22h 54m
1 stop
Multiple Airlines Logo
4:40 pm - 8:00 am
STI
-
IAH
17h 20m
1 stop
$316Multiple Airlines
Thu, Feb 19 - Fri, Feb 27
Multiple Airlines Logo
6:07 pm - 3:35 pm
IAH
-
STI
19h 28m
2 stops
Multiple Airlines Logo
4:40 pm - 12:18 am
STI
-
IAH
9h 38m
1 stop
$352Multiple Airlines
Wed, Feb 18 - Wed, Feb 25
Spirit Airlines Logo
7:21 am - 3:35 pm
IAH
-
STI
6h 14m
1 stop
Spirit Airlines Logo
4:40 pm - 8:00 am
STI
-
IAH
17h 20m
1 stop
$354Spirit Airlines
Sun, Feb 15 - Sun, Feb 22
Spirit Airlines Logo
7:45 am - 3:33 pm
IAH
-
STI
5h 48m
1 stop
Spirit Airlines Logo
4:40 pm - 11:58 pm
STI
-
IAH
9h 18m
1 stop
$356Spirit Airlines
Sat, Jan 31 - Thu, Feb 5
Delta Logo
5:25 am - 1:34 am
HOU
-
STI
18h 09m
2 stops
Delta Logo
9:59 pm - 4:28 pm
STI
-
HOU
20h 29m
2 stops
$583Delta
Thu, Feb 26 - Mon, Mar 2
American Airlines Logo
10:14 am - 8:29 pm
HOU
-
STI
9h 15m
2 stops
American Airlines Logo
7:00 am - 11:58 pm
STI
-
HOU
17h 58m
2 stops
$613American Airlines
Wed, Apr 1 - Sun, Apr 5
Delta Logo
6:00 am - 11:54 pm
HOU
-
STI
16h 54m
2 stops
Delta Logo
6:10 am - 10:44 pm
STI
-
HOU
17h 34m
2 stops
$633Delta
Wed, Apr 8 - Wed, Apr 15
American Airlines Logo
4:19 pm - 12:23 pm
HOU
-
STI
19h 04m
2 stops
American Airlines Logo
1:32 pm - 11:47 pm
STI
-
HOU
11h 15m
2 stops
$643American Airlines
Wed, Apr 8 - Wed, Apr 15

Spirit Airlines flights from Houston to Santiago de los Caballeros

Our best Spirit Airlines deals on Houston to Santiago de los Caballeros flight tickets
Spirit Airlines
Feb 18
IAH7:21 amHouston George Bush Intcntl
6h 14m
1 stop
STI3:35 pmSantiago de los Caballeros
Feb 25
STI4:40 pmSantiago de los Caballeros
9h 38m
1 stop
IAH12:18 amHouston George Bush Intcntl
$295
Spirit Airlines
Feb 19
IAH7:21 amHouston George Bush Intcntl
6h 14m
1 stop
STI3:35 pmSantiago de los Caballeros
Feb 26
STI4:40 pmSantiago de los Caballeros
9h 38m
1 stop
IAH12:18 amHouston George Bush Intcntl
$311
Spirit Airlines
Feb 15
IAH7:21 amHouston George Bush Intcntl
6h 14m
1 stop
STI3:35 pmSantiago de los Caballeros
Feb 22
STI4:40 pmSantiago de los Caballeros
17h 20m
1 stop
IAH8:00 amHouston George Bush Intcntl
$354

Delta flights from Houston to Santiago de los Caballeros

Our best Delta deals on Houston to Santiago de los Caballeros flight tickets
Delta
Feb 26
HOU5:25 amHouston Hobby
18h 09m
2 stops
STI1:34 amSantiago de los Caballeros
Mar 2
STI9:59 pmSantiago de los Caballeros
20h 29m
2 stops
HOU4:28 pmHouston Hobby
$583
Delta
Apr 8
IAH5:25 amHouston George Bush Intcntl
12h 50m
2 stops
STI7:15 pmSantiago de los Caballeros
Apr 15
STI6:10 amSantiago de los Caballeros
17h 44m
2 stops
IAH10:54 pmHouston George Bush Intcntl
$633
Delta
Apr 15
HOU5:20 pmHouston Hobby
17h 45m
2 stops
STI12:05 pmSantiago de los Caballeros
May 30
STI1:30 pmSantiago de los Caballeros
20h 50m
2 stops
HOU9:20 amHouston Hobby
$653

momondo Fare Finder

 
Customize your flight search to find flights from Houston to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Houston to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Wed 2/18

7:21 am-3:35 pm

1 stop6h 14m

Santiago de los Caballeros

Wed 2/25

4:40 pm-12:18 am

1 stop9h 38m

$295

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Thu 2/19

7:21 am-3:35 pm

1 stop6h 14m

Santiago de los Caballeros

Thu 2/26

4:40 pm-12:18 am

1 stop9h 38m

$311

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Thu 2/19

2:41 pm-3:35 pm

1 stop22h 54m

Santiago de los Caballeros

Fri 2/27

4:40 pm-8:00 am

1 stop17h 20m

$316

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Wed 2/18

6:07 pm-3:35 pm

2 stops19h 28m

Santiago de los Caballeros

Wed 2/25

4:40 pm-12:18 am

1 stop9h 38m

$352

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Sun 2/15

7:21 am-3:35 pm

1 stop6h 14m

Santiago de los Caballeros

Sun 2/22

4:40 pm-8:00 am

1 stop17h 20m

$354

HoustonSantiago de los Caballeros

IAH - STI

IAHSTI

Houston George Bush Intcntl

Sat 1/31

7:45 am-3:33 pm

1 stop5h 48m

Santiago de los Caballeros

Thu 2/5

4:40 pm-11:58 pm

1 stop9h 18m

$356

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Thu 2/26

5:25 am-1:34 am

2 stops18h 09m

Santiago de los Caballeros

Mon 3/2

9:59 pm-4:28 pm

2 stops20h 29m

$583

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Wed 4/1

10:14 am-8:29 pm

2 stops9h 15m

Santiago de los Caballeros

Sun 4/5

7:00 am-11:58 pm

2 stops17h 58m

$613

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Wed 4/8

6:00 am-11:54 pm

2 stops16h 54m

Santiago de los Caballeros

Wed 4/15

6:10 am-10:44 pm

2 stops17h 34m

$633

HoustonSantiago de los Caballeros

HOU - STI

HOUSTI

Houston Hobby

Wed 4/8

4:19 pm-12:23 pm

2 stops19h 04m

Santiago de los Caballeros

Wed 4/15

1:32 pm-11:47 pm

2 stops11h 15m

$643

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Houston to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago de los Caballeros?

The cheapest month to fly to Santiago de los Caballeros from Houston is in October. Flight prices, which tend to average around $313, are often lower during this time because this is during the off-season. If you aren’t able to travel to Santiago de los Caballeros during the month of October, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $443.

Cheap Houston to Santiago de los Caballeros flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Santiago de los Caballeros

Fastest flight time

6h 00m

Direct flights

None
The fastest flight from Houston to Santiago de los Caballeros takes 6h 00m
There are no direct flights from Houston to Santiago de los Caballeros. There are no popular flight routes from Houston to Santiago de los Caballeros.
Search flight deals

  • How far is Houston to Santiago de los Caballeros by plane?

    Santiago de los Caballeros is 1699.3 mi away from Houston. Flights usually cover this in 6h 00m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Houston to Santiago de los Caballeros Airport?

    Prices for flights from Houston to Santiago de los Caballeros Airport were last updated today.

  • How many operators does momondo search for flights from Houston to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Houston to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The necessary travel and health documents for your Santiago de los Caballeros Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Houston to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $265Free CancellationRating
6.3
8,361 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $514Free CancellationRating
7.2
11,169 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Santiago de los Caballeros?

It is quick and easy to find Houston to Santiago de los Caballeros flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago de los Caballeros that suits you.

Can I find flights from Houston to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Houston to Santiago de los Caballeros flights to just show those with flexible booking policies.

How can momondo help me find flights from Houston to Santiago de los Caballeros?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santiago de los Caballeros from Houston.

I’m not ready to book a flight from Houston to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Houston to Santiago de los Caballeros flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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