Cheap flights from Houston to Santiago from $292

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Santiago departing on 9/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Houston to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:00 am - 11:26 pm
IAH
-
SCL
40h 26m
3 stops
Multiple Airlines Logo
2:14 am - 6:25 pm
SCL
-
IAH
17h 11m
2 stops
$723Multiple Airlines
Mon, Aug 3 - Sun, Aug 16
Multiple Airlines Logo
8:37 pm - 6:55 am
IAH
-
SCL
33h 18m
1 stop
Multiple Airlines Logo
4:35 am - 8:45 am
SCL
-
IAH
30h 10m
2 stops
$782Multiple Airlines
Tue, Sep 1 - Wed, Sep 30
Air Canada Logo
12:10 pm - 5:50 am
IAH
-
SCL
14h 40m
1 stop
Air Canada Logo
8:55 pm - 5:08 pm
SCL
-
IAH
23h 13m
1 stop
$802Air Canada
Mon, Nov 30 - Tue, Dec 15
Air Canada Logo
12:10 pm - 5:50 am
IAH
-
SCL
14h 40m
1 stop
Air Canada Logo
7:25 am - 10:53 am
SCL
-
IAH
30h 28m
2 stops
$805Air Canada
Mon, Nov 30 - Tue, Dec 15
LATAM Airlines Logo
10:50 am - 7:15 am
HOU
-
SCL
19h 25m
1 stop
LATAM Airlines Logo
8:40 pm - 12:16 pm
SCL
-
HOU
16h 36m
1 stop
$1,133LATAM Airlines
Tue, Aug 11 - Tue, Aug 18
Delta Logo
5:35 pm - 7:15 am
HOU
-
SCL
12h 40m
1 stop
Delta Logo
8:40 pm - 4:23 pm
SCL
-
HOU
20h 43m
1 stop
$1,135Delta
Thu, Aug 20 - Wed, Sep 2
American Airlines Logo
12:14 pm - 7:05 am
HOU
-
SCL
17h 51m
2 stops
American Airlines Logo
8:50 pm - 3:26 pm
SCL
-
HOU
19h 36m
2 stops
$1,140American Airlines
Fri, Aug 21 - Fri, Sep 4
American Airlines Logo
12:14 pm - 7:05 am
HOU
-
SCL
17h 51m
2 stops
American Airlines Logo
9:30 pm - 12:23 pm
SCL
-
HOU
16h 53m
2 stops
$1,142American Airlines
Fri, Aug 21 - Sun, Oct 4
LATAM Airlines Logo
1:13 pm - 7:15 am
HOU
-
SCL
17h 02m
1 stop
LATAM Airlines Logo
8:40 pm - 10:01 am
SCL
-
HOU
15h 21m
1 stop
$1,164LATAM Airlines
Tue, Sep 1 - Wed, Sep 30
Delta Logo
5:35 pm - 7:15 am
HOU
-
SCL
12h 40m
1 stop
Delta Logo
8:40 pm - 4:23 pm
SCL
-
HOU
20h 43m
1 stop
$1,175Delta
Tue, Aug 18 - Fri, Sep 4

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LATAM Airlines flights from Houston to Santiago

Our best LATAM Airlines deals on Houston to Santiago flight tickets
LATAM Airlines
Aug 11
HOU10:50 amHouston Hobby
19h 25m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
Aug 18
SCL8:40 pmSantiago Arturo Merino Benitez
16h 36m
1 stop
HOU12:16 pmHouston Hobby
$1,133
LATAM Airlines
Sep 1
HOU1:13 pmHouston Hobby
17h 02m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
Sep 30
SCL8:40 pmSantiago Arturo Merino Benitez
15h 21m
1 stop
HOU10:01 amHouston Hobby
$1,164
LATAM Airlines
Aug 14
HOU1:13 pmHouston Hobby
17h 02m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
Aug 31
SCL8:40 pmSantiago Arturo Merino Benitez
14h 10m
1 stop
HOU9:50 amHouston Hobby
$1,171

Delta flights from Houston to Santiago

Our best Delta deals on Houston to Santiago flight tickets
Delta
Aug 20
HOU5:35 pmHouston Hobby
12h 40m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
Sep 7
SCL8:40 pmSantiago Arturo Merino Benitez
21h 43m
1 stop
HOU4:23 pmHouston Hobby
$1,135
Delta
Aug 18
HOU5:35 pmHouston Hobby
12h 40m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
Sep 4
SCL8:40 pmSantiago Arturo Merino Benitez
20h 43m
1 stop
HOU4:23 pmHouston Hobby
$1,175
Delta
Dec 12
HOU5:35 pmHouston Hobby
34h 05m
1 stop
SCL6:40 amSantiago Arturo Merino Benitez
Jan 26
SCL9:50 pmSantiago Arturo Merino Benitez
21h 33m
1 stop
HOU4:23 pmHouston Hobby
$1,186

momondo Fare Finder

 
Customize your flight search to find flights from Houston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 15, 2026.
Use the filters below to find and compare flights from Houston to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Mon 8/3

6:00 am-11:26 pm

3 stops40h 26m

Santiago Arturo Merino Benitez

Sun 8/16

2:14 am-6:25 pm

2 stops17h 11m

$723

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Tue 9/1

8:37 pm-6:55 am

1 stop33h 18m

Santiago Arturo Merino Benitez

Wed 9/30

4:35 am-8:45 am

2 stops30h 10m

$782

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Mon 11/30

12:10 pm-5:50 am

1 stop14h 40m

Santiago Arturo Merino Benitez

Tue 12/15

8:55 pm-5:08 pm

1 stop23h 13m

$802

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Mon 11/30

12:10 pm-5:50 am

1 stop14h 40m

Santiago Arturo Merino Benitez

Tue 12/15

7:25 am-10:53 am

2 stops30h 28m

$805

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Tue 8/11

10:50 am-7:15 am

1 stop19h 25m

Santiago Arturo Merino Benitez

Tue 8/18

8:40 pm-12:16 pm

1 stop16h 36m

$1,133

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Thu 8/20

5:35 pm-7:15 am

1 stop12h 40m

Santiago Arturo Merino Benitez

Wed 9/2

8:40 pm-4:23 pm

1 stop20h 43m

$1,135

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 8/21

12:14 pm-7:05 am

2 stops17h 51m

Santiago Arturo Merino Benitez

Fri 9/4

8:50 pm-3:26 pm

2 stops19h 36m

$1,140

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 8/21

12:14 pm-7:05 am

2 stops17h 51m

Santiago Arturo Merino Benitez

Sun 10/4

9:30 pm-12:23 pm

2 stops16h 53m

$1,142
Quickest round-trip

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Tue 9/1

1:13 pm-7:15 am

1 stop17h 02m

Santiago Arturo Merino Benitez

Wed 9/30

8:40 pm-10:01 am

1 stop15h 21m

$1,164

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Tue 8/18

5:35 pm-7:15 am

1 stop12h 40m

Santiago Arturo Merino Benitez

Fri 9/4

8:40 pm-4:23 pm

1 stop20h 43m

$1,175

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Houston to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Houston and Santiago?

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Houston to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $96. If you don’t want to visit Santiago in September, then you should wait until November to fly from Houston, when ticket prices are also cheap, with an average price of $325.

What is the cheapest Houston to Santiago Arturo Merino Benitez flight route?

Fly from Houston George Bush Intcntl to Santiago Arturo Merino Benitez for the best Houston - Santiago Arturo Merino Benitez flight prices

What cabin class options are available on Houston to Santiago flights?

There are 2 cabin classes available to choose from on Houston to Santiago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to Santiago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Santiago

Fastest flight time

9h 20m

Direct flights

Mon, Tue, Thu, Fri and Sun

Airports in Santiago

1 airport
The fastest flight from Houston to Santiago takes 9h 20m
Direct flights go from Houston to Santiago on Monday, Tuesday, Thursday, Friday and Sunday. There are no airlines offering direct flights.
There is 1 airport in Santiago. From Houston there are direct flights to Santiago Arturo Merino Benitez (SCL).

Frequently asked questions about flying from Houston to Santiago

  • How far is Houston to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Houston to Santiago Arturo Merino Benitez is 4652.9 mi. A reasonable flight in good conditions will take 9h 20m.

  • When did momondo last update prices for flights from Houston to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Houston to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Houston to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Houston to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Santiago

Compare and see reviews for airlines that fly from Houston to Santiago with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $949Free CancellationRating
7.4
1,934 reviews
Search LATAM Airlines flights
United AirlinesPriceFrom $949Free CancellationRating
7.4
9,841 reviews
Search United Airlines flights
American AirlinesPriceFrom $1,005Free CancellationRating
7.1
11,660 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Santiago?

It is quick and easy to find Houston to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Houston to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Houston which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Houston to Santiago?

Once you have performed a search for Houston to Santiago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

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Of course. momondo tracks the price of Houston to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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1 adult
Wed 7/15
Wed 7/22

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