Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Houston to Santiago from $261

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Santiago departing on 3/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Houston to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:24 pm - 10:15 pm
IAH
-
SCL
26h 51m
2 stops
Multiple Airlines Logo
7:15 am - 11:49 pm
SCL
-
IAH
18h 34m
2 stops
$580Multiple Airlines
Wed, Mar 18 - Tue, Mar 24
Multiple Airlines Logo
5:24 pm - 10:15 pm
IAH
-
SCL
26h 51m
2 stops
Multiple Airlines Logo
8:15 am - 11:49 pm
SCL
-
IAH
17h 34m
1 stop
$581Multiple Airlines
Tue, Mar 17 - Mon, Mar 23
Multiple Airlines Logo
5:24 pm - 10:15 pm
IAH
-
SCL
26h 51m
2 stops
Multiple Airlines Logo
8:15 am - 11:49 pm
SCL
-
IAH
17h 34m
1 stop
$583Multiple Airlines
Mon, Mar 16 - Mon, Mar 23
Multiple Airlines Logo
2:39 pm - 9:15 pm
IAH
-
SCL
29h 36m
2 stops
Multiple Airlines Logo
11:00 pm - 11:51 pm
SCL
-
IAH
25h 51m
1 stop
$584Multiple Airlines
Sun, May 17 - Tue, May 26
Delta Logo
6:00 am - 6:00 am
HOU
-
SCL
23h 00m
2 stops
Delta Logo
12:20 pm - 4:26 pm
SCL
-
HOU
29h 06m
2 stops
$985Delta
Thu, May 21 - Mon, Jun 1
LATAM Airlines Logo
10:46 am - 7:15 am
HOU
-
SCL
19h 29m
1 stop
LATAM Airlines Logo
8:40 pm - 9:20 am
SCL
-
HOU
13h 40m
1 stop
$1,017LATAM Airlines
Fri, May 1 - Wed, May 13
LATAM Airlines Logo
1:31 pm - 6:55 am
HOU
-
SCL
16h 24m
2 stops
LATAM Airlines Logo
7:45 pm - 12:10 pm
SCL
-
HOU
17h 25m
2 stops
$1,022LATAM Airlines
Fri, May 1 - Wed, May 13
Delta Logo
6:00 am - 6:00 am
HOU
-
SCL
23h 00m
2 stops
Delta Logo
12:20 pm - 12:10 pm
SCL
-
HOU
24h 50m
2 stops
$1,025Delta
Fri, May 15 - Mon, Jun 1
American Airlines Logo
12:18 pm - 7:00 am
HOU
-
SCL
16h 42m
1 stop
American Airlines Logo
10:15 pm - 3:50 pm
SCL
-
HOU
19h 35m
1 stop
$1,110American Airlines
Wed, Mar 11 - Thu, Mar 19
American Airlines Logo
4:20 pm - 9:05 am
HOU
-
SCL
14h 45m
2 stops
American Airlines Logo
10:15 pm - 9:43 am
SCL
-
HOU
13h 28m
1 stop
$1,115American Airlines
Wed, Mar 11 - Thu, Mar 19

American Airlines flights from Houston to Santiago

Our best American Airlines deals on Houston to Santiago flight tickets
American Airlines
Mar 11
HOU12:18 pmHouston Hobby
16h 42m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Mar 19
SCL10:15 pmSantiago Arturo Merino Benitez
19h 35m
1 stop
HOU3:50 pmHouston Hobby
$1,110
American Airlines
Mar 11
HOU4:20 pmHouston Hobby
14h 45m
2 stops
SCL9:05 amSantiago Arturo Merino Benitez
Mar 19
SCL10:15 pmSantiago Arturo Merino Benitez
13h 28m
1 stop
HOU9:43 amHouston Hobby
$1,115
American Airlines
Mar 2
HOU10:13 amHouston Hobby
18h 52m
1 stop
SCL8:05 amSantiago Arturo Merino Benitez
Mar 15
SCL10:15 pmSantiago Arturo Merino Benitez
19h 35m
1 stop
HOU3:50 pmHouston Hobby
$1,291

GOL flights from Houston to Santiago

Our best GOL deals on Houston to Santiago flight tickets
GOL
Feb 3
HOU4:55 pmHouston Hobby
12h 20m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
Feb 28
SCL11:15 pmSantiago Arturo Merino Benitez
15h 33m
1 stop
HOU11:48 amHouston Hobby
$1,855
GOL
Feb 3
HOU4:55 pmHouston Hobby
12h 20m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
Feb 25
SCL11:15 pmSantiago Arturo Merino Benitez
15h 33m
1 stop
HOU11:48 amHouston Hobby
$1,872
GOL
Feb 8
HOU4:55 pmHouston Hobby
12h 20m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
Feb 11
SCL10:30 pmSantiago Arturo Merino Benitez
16h 18m
1 stop
HOU11:48 amHouston Hobby
$2,259

momondo Fare Finder

 
Customize your flight search to find flights from Houston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Houston to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Wed 3/18

5:24 pm-10:15 pm

2 stops26h 51m

Santiago Arturo Merino Benitez

Tue 3/24

7:15 am-11:49 pm

2 stops18h 34m

$580

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Tue 3/17

5:24 pm-10:15 pm

2 stops26h 51m

Santiago Arturo Merino Benitez

Mon 3/23

8:15 am-11:49 pm

1 stop17h 34m

$581

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Mon 3/16

5:24 pm-10:15 pm

2 stops26h 51m

Santiago Arturo Merino Benitez

Mon 3/23

8:15 am-11:49 pm

1 stop17h 34m

$583

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Sun 5/17

2:39 pm-9:15 pm

2 stops29h 36m

Santiago Arturo Merino Benitez

Tue 5/26

11:00 pm-11:51 pm

1 stop25h 51m

$584

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Thu 5/21

6:00 am-6:00 am

2 stops23h 00m

Santiago Arturo Merino Benitez

Mon 6/1

12:20 pm-4:26 pm

2 stops29h 06m

$985

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 5/1

10:46 am-7:15 am

1 stop19h 29m

Santiago Arturo Merino Benitez

Wed 5/13

8:40 pm-9:20 am

1 stop13h 40m

$1,017

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 5/1

1:31 pm-6:55 am

2 stops16h 24m

Santiago Arturo Merino Benitez

Wed 5/13

7:45 pm-12:10 pm

2 stops17h 25m

$1,022

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 5/15

6:00 am-6:00 am

2 stops23h 00m

Santiago Arturo Merino Benitez

Mon 6/1

12:20 pm-12:10 pm

2 stops24h 50m

$1,025

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Wed 3/11

12:18 pm-7:00 am

1 stop16h 42m

Santiago Arturo Merino Benitez

Thu 3/19

10:15 pm-3:50 pm

1 stop19h 35m

$1,110

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Wed 3/11

4:20 pm-9:05 am

2 stops14h 45m

Santiago Arturo Merino Benitez

Thu 3/19

10:15 pm-9:43 am

1 stop13h 28m

$1,115

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Santiago from

How to get the cheapest flight ticket from Houston to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, April is the cheapest month to fly from Houston to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $720. If you don’t want to visit Santiago in April, then you should wait until May to fly from Houston, when ticket prices are also cheap, with an average price of $847.

What is the cheapest Houston to Santiago Arturo Merino Benitez flight route?

Fly from Houston George Bush Intcntl to Santiago Arturo Merino Benitez for the best Houston - Santiago Arturo Merino Benitez flight prices

What cabin class options are available on Houston to Santiago Arturo Merino Benitez flights?

There are 3 cabin classes available to choose from on Houston to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to Santiago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Santiago

Fastest flight time

9h 05m

Direct flights

Mon, Tue, Wed, Thu, Fri and Sun

Airports in Santiago

1 airport
The fastest flight from Houston to Santiago takes 9h 05m
Direct flights go from Houston to Santiago on Monday, Tuesday, Wednesday, Thursday, Friday and Sunday. There are no airlines offering direct flights.
There is 1 airport in Santiago. From Houston there are direct flights to Santiago Arturo Merino Benitez (SCL).
Search flight deals

  • How far is Houston to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Houston to Santiago Arturo Merino Benitez is 4652.9 mi. A reasonable flight in good conditions will take 9h 05m.

  • When did momondo last update prices for flights from Houston to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Houston to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Houston to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Houston to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Santiago

Compare and see reviews for airlines that fly from Houston to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $548Free CancellationRating
6.6
2,490 reviews
Search Avianca flights
LATAM AirlinesPriceFrom $949Free CancellationRating
7.5
1,916 reviews
Search LATAM Airlines flights
United AirlinesPriceFrom $949Free CancellationRating
7.4
9,214 reviews
Search United Airlines flights
American AirlinesPriceFrom $964Free CancellationRating
7.2
11,199 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Santiago?

It is quick and easy to find Houston to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Houston to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Houston which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Houston to Santiago?

Once you have performed a search for Houston to Santiago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Houston to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Houston to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Santiago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 2/28
Sat 3/7
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Chile