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Cheap flights from Houston to Santiago from $209

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Santiago departing on 12/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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Multiple Airlines Logo
5:25 pm - 10:15 pmIAH-SCL
25h 50m2 stops
Multiple Airlines Logo
9:05 pm - 11:59 pmSCL-IAH
29h 54m2 stops
$484Multiple Airlines
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Thu, Dec 4 - Thu, Dec 11
Multiple Airlines Logo
10:17 am - 10:15 pmIAH-SCL
32h 58m3 stops
Multiple Airlines Logo
9:05 pm - 11:59 pmSCL-IAH
29h 54m2 stops
$512Multiple Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
Air Canada Logo
12:10 pm - 6:50 amIAH-SCL
15h 40m1 stop
Air Canada Logo
8:55 pm - 11:09 amSCL-IAH
17h 14m1 stop
$696Air Canada
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Tue, Jan 27 - Wed, Feb 11
Air Canada Logo
7:10 am - 12:15 pmIAH-SCL
26h 05m1 stop
Air Canada Logo
8:55 pm - 9:39 pmSCL-IAH
27h 44m2 stops
$698Air Canada
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Mon, Feb 2 - Tue, Feb 17
American Airlines Logo
4:17 pm - 7:45 amHOU-SCL
12h 28m1 stop
American Airlines Logo
10:30 pm - 8:34 amSCL-HOU
13h 04m1 stop
$955American Airlines
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Mon, Dec 29 - Wed, Jan 14
LATAM Airlines Logo
11:09 am - 7:40 amHOU-SCL
17h 31m1 stop
LATAM Airlines Logo
11:15 pm - 12:21 pmSCL-HOU
16h 06m1 stop
$964LATAM Airlines
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Mon, Feb 2 - Tue, Feb 17
LATAM Airlines Logo
5:35 pm - 2:05 pmHOU-SCL
18h 30m2 stops
LATAM Airlines Logo
12:25 am - 9:46 pmSCL-HOU
23h 21m2 stops
$988LATAM Airlines
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Thu, Mar 12 - Fri, Mar 20
Delta Logo
6:00 am - 5:50 amHOU-SCL
22h 50m2 stops
Delta Logo
4:55 pm - 12:10 pmSCL-HOU
20h 15m2 stops
$1,004Delta
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Fri, May 1 - Wed, May 13
Delta Logo
10:05 am - 1:35 pmHOU-SCL
25h 30m2 stops
Delta Logo
10:35 am - 12:21 pmSCL-HOU
27h 46m2 stops
$1,009Delta
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Thu, Mar 12 - Sat, Mar 21
American Airlines Logo
4:25 pm - 8:00 amHOU-SCL
12h 35m1 stop
American Airlines Logo
10:30 pm - 8:34 amSCL-HOU
13h 04m1 stop
$1,089American Airlines
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Mon, Dec 1 - Wed, Jan 14

Air Canada flights from Houston to Santiago

Our best Air Canada deals on Houston to Santiago flight tickets
Air Canada
Jan 27
IAH12:10 pmHouston George Bush Intcntl
15h 40m
1 stop
SCL6:50 amSantiago Arturo Merino Benitez
Feb 11
SCL8:55 pmSantiago Arturo Merino Benitez
17h 14m
1 stop
IAH11:09 amHouston George Bush Intcntl
$696
Find similar
Air Canada
Feb 2
IAH7:10 amHouston George Bush Intcntl
26h 05m
1 stop
SCL12:15 pmSantiago Arturo Merino Benitez
Feb 17
SCL8:55 pmSantiago Arturo Merino Benitez
27h 44m
2 stops
IAH9:39 pmHouston George Bush Intcntl
$698
Find similar
Air Canada
Nov 17
IAH7:10 amHouston George Bush Intcntl
26h 05m
1 stop
SCL12:15 pmSantiago Arturo Merino Benitez
Nov 24
SCL8:55 pmSantiago Arturo Merino Benitez
24h 43m
1 stop
IAH6:38 pmHouston George Bush Intcntl
$701
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American Airlines flights from Houston to Santiago

Our best American Airlines deals on Houston to Santiago flight tickets
American Airlines
Dec 29
HOU4:17 pmHouston Hobby
12h 28m
1 stop
SCL7:45 amSantiago Arturo Merino Benitez
Jan 14
SCL10:30 pmSantiago Arturo Merino Benitez
13h 04m
1 stop
HOU8:34 amHouston Hobby
$955
Find similar
American Airlines
Dec 1
HOU4:25 pmHouston Hobby
12h 35m
1 stop
SCL8:00 amSantiago Arturo Merino Benitez
Jan 14
SCL10:30 pmSantiago Arturo Merino Benitez
13h 04m
1 stop
HOU8:34 amHouston Hobby
$1,089
Find similar
American Airlines
Dec 4
HOU12:16 pmHouston Hobby
17h 39m
2 stops
SCL8:55 amSantiago Arturo Merino Benitez
Dec 11
SCL11:15 pmSantiago Arturo Merino Benitez
13h 23m
1 stop
HOU9:38 amHouston Hobby
$1,219
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momondo Fare Finder

 
Customize your flight search to find flights from Houston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Houston to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Thu 12/4

5:25 pm-10:15 pm

2 stops25h 50m

Santiago Arturo Merino Benitez

Thu 12/11

9:05 pm-11:59 pm

2 stops29h 54m

$484

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Thu 12/4

10:17 am-10:15 pm

3 stops32h 58m

Santiago Arturo Merino Benitez

Thu 12/11

9:05 pm-11:59 pm

2 stops29h 54m

$512

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Tue 1/27

12:10 pm-6:50 am

1 stop15h 40m

Santiago Arturo Merino Benitez

Wed 2/11

8:55 pm-11:09 am

1 stop17h 14m

$696

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Mon 2/2

7:10 am-12:15 pm

1 stop26h 05m

Santiago Arturo Merino Benitez

Tue 2/17

8:55 pm-9:39 pm

2 stops27h 44m

$698

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Mon 12/29

4:17 pm-7:45 am

1 stop12h 28m

Santiago Arturo Merino Benitez

Wed 1/14

10:30 pm-8:34 am

1 stop13h 04m

$955

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Mon 2/2

11:09 am-7:40 am

1 stop17h 31m

Santiago Arturo Merino Benitez

Tue 2/17

11:15 pm-12:21 pm

1 stop16h 06m

$964

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Thu 3/12

5:35 pm-2:05 pm

2 stops18h 30m

Santiago Arturo Merino Benitez

Fri 3/20

12:25 am-9:46 pm

2 stops23h 21m

$988

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 5/1

6:00 am-5:50 am

2 stops22h 50m

Santiago Arturo Merino Benitez

Wed 5/13

4:55 pm-12:10 pm

2 stops20h 15m

$1,004

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Thu 3/12

10:05 am-1:35 pm

2 stops25h 30m

Santiago Arturo Merino Benitez

Sat 3/21

10:35 am-12:21 pm

2 stops27h 46m

$1,009

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Mon 12/1

4:25 pm-8:00 am

1 stop12h 35m

Santiago Arturo Merino Benitez

Wed 1/14

10:30 pm-8:34 am

1 stop13h 04m

$1,089

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Houston to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, May is the cheapest month to fly from Houston to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $847. If you don’t want to visit Santiago in May, then you should wait until March to fly from Houston, when ticket prices are also cheap, with an average price of $989.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $1,037. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Sunday is $1,557.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from Houston to Santiago when you can find flight prices for as low as $981. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,499 per ticket.

What is the cheapest Houston to Santiago Arturo Merino Benitez flight route?

Fly from Houston George Bush Intcntl to Santiago Arturo Merino Benitez for the best Houston - Santiago Arturo Merino Benitez flight prices

What cabin class options are available on Houston to Santiago Arturo Merino Benitez flights?

There are 3 cabin classes available to choose from on Houston to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to Santiago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Santiago

Fastest flight time

9h 05m

Direct flights

Every day

Airports in Santiago

1 airport
The fastest flight from Houston to Santiago takes 9h 05m
Direct flights go from Houston to Santiago every day.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)
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  • How far is Houston to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Houston to Santiago Arturo Merino Benitez is 4652.9 mi. A reasonable flight in good conditions will take 12h 25m.

  • When did momondo last update prices for flights from Houston to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Houston to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Houston to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Houston to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Santiago

Compare and see reviews for airlines that fly from Houston to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $499Free CancellationRating
6.6
2,471 reviews
Search Avianca flights
United AirlinesPriceFrom $949Free CancellationRating
7.4
9,000 reviews
Search United Airlines flights
DeltaPriceFrom $963Free CancellationRating
7.9
8,004 reviews
Search Delta flights
LATAM AirlinesPriceFrom $963Free CancellationRating
7.5
1,874 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $1,242Free CancellationRating
7.2
11,039 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Santiago?

It is quick and easy to find Houston to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Houston to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Houston which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Houston to Santiago?

Once you have performed a search for Houston to Santiago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Houston to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Houston to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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