Cheap flights from Houston to Santiago from $284

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Santiago departing on 3/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:43 am - 5:30 am
IAH
-
SCL
16h 47m
2 stops
Multiple Airlines Logo
8:40 am - 3:27 pm
SCL
-
IAH
31h 47m
2 stops
$553Multiple Airlines
Tue, Apr 21 - Fri, Apr 24
Multiple Airlines Logo
5:24 pm - 6:40 am
IAH
-
SCL
35h 16m
2 stops
Multiple Airlines Logo
10:30 am - 11:49 pm
SCL
-
IAH
14h 19m
1 stop
$586Multiple Airlines
Sat, Mar 28 - Wed, Apr 8
Multiple Airlines Logo
5:24 pm - 10:15 pm
IAH
-
SCL
26h 51m
2 stops
Multiple Airlines Logo
10:35 am - 11:49 pm
SCL
-
IAH
15h 14m
1 stop
$590Multiple Airlines
Mon, Mar 23 - Sat, Mar 28
Multiple Airlines Logo
5:24 pm - 6:40 am
IAH
-
SCL
35h 16m
2 stops
Multiple Airlines Logo
10:30 am - 11:49 pm
SCL
-
IAH
14h 19m
1 stop
$591Multiple Airlines
Sat, Mar 28 - Tue, Apr 7
Delta Logo
1:06 pm - 7:15 am
HOU
-
SCL
17h 09m
1 stop
Delta Logo
12:20 pm - 4:09 pm
SCL
-
HOU
28h 49m
2 stops
$985Delta
Thu, May 21 - Mon, Jun 1
LATAM Airlines Logo
5:35 pm - 7:45 pm
HOU
-
SCL
25h 10m
2 stops
LATAM Airlines Logo
8:40 pm - 9:15 am
SCL
-
HOU
13h 35m
1 stop
$990LATAM Airlines
Sun, Aug 9 - Thu, Aug 27
LATAM Airlines Logo
1:00 pm - 7:15 am
HOU
-
SCL
17h 15m
1 stop
LATAM Airlines Logo
8:40 pm - 12:04 pm
SCL
-
HOU
16h 24m
1 stop
$1,017LATAM Airlines
Sat, Aug 15 - Mon, Aug 24
LATAM Airlines Logo
5:35 pm - 4:30 pm
HOU
-
SCL
21h 55m
2 stops
LATAM Airlines Logo
11:05 pm - 9:35 pm
SCL
-
HOU
24h 30m
2 stops
$1,027LATAM Airlines
Fri, Aug 21 - Sun, Oct 4
LATAM Airlines Logo
6:00 am - 6:00 am
HOU
-
SCL
23h 00m
2 stops
LATAM Airlines Logo
6:00 pm - 10:26 pm
SCL
-
HOU
29h 26m
3 stops
$1,030LATAM Airlines
Fri, May 15 - Mon, Jun 1
Delta Logo
1:00 pm - 7:15 am
HOU
-
SCL
17h 15m
1 stop
Delta Logo
8:40 pm - 9:15 am
SCL
-
HOU
14h 35m
1 stop
$1,065Delta
Fri, Aug 21 - Sun, Oct 4

LATAM Airlines flights from Houston to Santiago

Our best LATAM Airlines deals on Houston to Santiago flight tickets
LATAM Airlines
Aug 9
HOU5:35 pmHouston Hobby
25h 10m
2 stops
SCL7:45 pmSantiago Arturo Merino Benitez
Aug 27
SCL8:40 pmSantiago Arturo Merino Benitez
13h 35m
1 stop
HOU9:15 amHouston Hobby
$990
LATAM Airlines
Aug 15
HOU1:00 pmHouston Hobby
17h 15m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
Aug 24
SCL8:40 pmSantiago Arturo Merino Benitez
16h 24m
1 stop
HOU12:04 pmHouston Hobby
$1,017
LATAM Airlines
Aug 21
HOU5:35 pmHouston Hobby
21h 55m
2 stops
SCL4:30 pmSantiago Arturo Merino Benitez
Oct 4
SCL11:05 pmSantiago Arturo Merino Benitez
24h 30m
2 stops
HOU9:35 pmHouston Hobby
$1,027

Delta flights from Houston to Santiago

Our best Delta deals on Houston to Santiago flight tickets
Delta
May 21
HOU1:06 pmHouston Hobby
17h 09m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
Jun 1
SCL12:20 pmSantiago Arturo Merino Benitez
28h 49m
2 stops
HOU4:09 pmHouston Hobby
$985
Delta
Aug 21
HOU1:00 pmHouston Hobby
17h 15m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
Oct 4
SCL8:40 pmSantiago Arturo Merino Benitez
14h 35m
1 stop
HOU9:15 amHouston Hobby
$1,065
Delta
Jul 25
HOU6:00 amHouston Hobby
23h 00m
2 stops
SCL6:00 amSantiago Arturo Merino Benitez
Aug 1
SCL10:55 pmSantiago Arturo Merino Benitez
23h 43m
2 stops
HOU9:38 pmHouston Hobby
$1,070

momondo Fare Finder

 
Customize your flight search to find flights from Houston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 28, 2026.
Use the filters below to find and compare flights from Houston to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Tue 4/21

11:43 am-5:30 am

2 stops16h 47m

Santiago Arturo Merino Benitez

Fri 4/24

8:40 am-3:27 pm

2 stops31h 47m

$553

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Sat 3/28

5:24 pm-6:40 am

2 stops35h 16m

Santiago Arturo Merino Benitez

Wed 4/8

10:30 am-11:49 pm

1 stop14h 19m

$586

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Mon 3/23

5:24 pm-10:15 pm

2 stops26h 51m

Santiago Arturo Merino Benitez

Sat 3/28

10:35 am-11:49 pm

1 stop15h 14m

$590

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Sat 3/28

5:24 pm-6:40 am

2 stops35h 16m

Santiago Arturo Merino Benitez

Tue 4/7

10:30 am-11:49 pm

1 stop14h 19m

$591

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Thu 5/21

1:06 pm-7:15 am

1 stop17h 09m

Santiago Arturo Merino Benitez

Mon 6/1

12:20 pm-4:09 pm

2 stops28h 49m

$985

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Sun 8/9

5:35 pm-7:45 pm

2 stops25h 10m

Santiago Arturo Merino Benitez

Thu 8/27

8:40 pm-9:15 am

1 stop13h 35m

$990

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Sat 8/15

1:00 pm-7:15 am

1 stop17h 15m

Santiago Arturo Merino Benitez

Mon 8/24

8:40 pm-12:04 pm

1 stop16h 24m

$1,017

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 8/21

5:35 pm-4:30 pm

2 stops21h 55m

Santiago Arturo Merino Benitez

Sun 10/4

11:05 pm-9:35 pm

2 stops24h 30m

$1,027

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 5/15

6:00 am-6:00 am

2 stops23h 00m

Santiago Arturo Merino Benitez

Mon 6/1

6:00 pm-10:26 pm

3 stops29h 26m

$1,030

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 8/21

1:00 pm-7:15 am

1 stop17h 15m

Santiago Arturo Merino Benitez

Sun 10/4

8:40 pm-9:15 am

1 stop14h 35m

$1,065

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Houston to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Houston and Santiago?

What is the cheapest month to fly to Santiago?

In general, April is the cheapest month to fly from Houston to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $720. If you don’t want to visit Santiago in April, then you should wait until May to fly from Houston, when ticket prices are also cheap, with an average price of $847.

What is the cheapest Houston to Santiago Arturo Merino Benitez flight route?

Fly from Houston George Bush Intcntl to Santiago Arturo Merino Benitez for the best Houston - Santiago Arturo Merino Benitez flight prices

What cabin class options are available on Houston to Santiago Arturo Merino Benitez flights?

There are 3 cabin classes available to choose from on Houston to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to Santiago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Santiago

Fastest flight time

9h 05m

Direct flights

Mon, Tue, Wed, Thu, Fri and Sat

Airports in Santiago

1 airport
The fastest flight from Houston to Santiago takes 9h 05m
Direct flights go from Houston to Santiago on Monday, Tuesday, Wednesday, Thursday, Friday and Saturday. There are no airlines offering direct flights.
There is 1 airport in Santiago. From Houston there are direct flights to Santiago Arturo Merino Benitez (SCL).
  • How far is Houston to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Houston to Santiago Arturo Merino Benitez is 4652.9 mi. A reasonable flight in good conditions will take 9h 05m.

  • When did momondo last update prices for flights from Houston to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Houston to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Houston to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Houston to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Santiago

Compare and see reviews for airlines that fly from Houston to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $548Free CancellationRating
6.5
2,495 reviews
Search Avianca flights
LATAM AirlinesPriceFrom $949Free CancellationRating
7.5
1,925 reviews
Search LATAM Airlines flights
United AirlinesPriceFrom $949Free CancellationRating
7.4
9,362 reviews
Search United Airlines flights
American AirlinesPriceFrom $964Free CancellationRating
7.1
11,367 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Santiago?

It is quick and easy to find Houston to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Houston to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Houston which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Houston to Santiago?

Once you have performed a search for Houston to Santiago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Houston to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Houston to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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1 adult
Mon 3/30
Mon 4/6

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