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Cheap flights from Houston to Santiago from $264

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Santiago departing on 1/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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Multiple Airlines Logo
5:00 am - 2:40 pmIAH-SCL
30h 40m2 stops
Multiple Airlines Logo
6:00 am - 11:59 pmSCL-IAH
20h 59m2 stops
$556Multiple Airlines
Find Deal
Mon, Dec 8 - Mon, Dec 15
Multiple Airlines Logo
10:41 am - 4:00 amIAH-SCL
38h 19m3 stops
Multiple Airlines Logo
6:00 am - 11:59 pmSCL-IAH
20h 59m2 stops
$573Multiple Airlines
Find Deal
Mon, Dec 8 - Mon, Dec 15
Multiple Airlines Logo
5:00 am - 2:40 pmIAH-SCL
30h 40m2 stops
Multiple Airlines Logo
6:00 am - 11:59 pmSCL-IAH
20h 59m2 stops
$594Multiple Airlines
Find Deal
Mon, Dec 8 - Mon, Dec 15
Multiple Airlines Logo
10:41 am - 4:00 amIAH-SCL
38h 19m3 stops
Multiple Airlines Logo
6:00 am - 11:59 pmSCL-IAH
20h 59m2 stops
$597Multiple Airlines
Find Deal
Mon, Dec 8 - Mon, Dec 15
Delta Logo
11:09 am - 11:35 amHOU-SCL
21h 26m2 stops
Delta Logo
6:30 pm - 4:30 pmSCL-HOU
25h 00m2 stops
$964Delta
Find Deal
Mon, Feb 2 - Tue, Feb 17
LATAM Airlines Logo
11:09 am - 2:30 pmHOU-SCL
24h 21m3 stops
LATAM Airlines Logo
6:30 pm - 10:21 amSCL-HOU
18h 51m2 stops
$969LATAM Airlines
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Thu, Jan 8 - Wed, Jan 21
LATAM Airlines Logo
5:35 pm - 5:55 pmHOU-SCL
21h 20m2 stops
LATAM Airlines Logo
6:30 pm - 10:05 amSCL-HOU
18h 35m2 stops
$996LATAM Airlines
Find Deal
Sat, Feb 14 - Mon, Mar 2
LATAM Airlines Logo
1:00 pm - 5:35 amHOU-SCL
15h 35m2 stops
LATAM Airlines Logo
6:45 pm - 12:10 pmSCL-HOU
18h 25m2 stops
$1,001LATAM Airlines
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Fri, May 1 - Wed, May 13
Delta Logo
5:35 pm - 2:00 pmHOU-SCL
19h 25m2 stops
Delta Logo
11:25 pm - 9:38 pmSCL-HOU
23h 13m2 stops
$1,004Delta
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Fri, May 15 - Mon, Jun 1
LATAM Airlines Logo
10:05 am - 6:00 amHOU-SCL
18h 55m3 stops
LATAM Airlines Logo
11:00 pm - 9:38 pmSCL-HOU
23h 38m2 stops
$1,009LATAM Airlines
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Fri, May 15 - Mon, Jun 1

Air Canada flights from Houston to Santiago

Our best Air Canada deals on Houston to Santiago flight tickets
Air Canada
Feb 14
IAH12:10 pmHouston George Bush Intcntl
45h 05m
2 stops
SCL12:15 pmSantiago Arturo Merino Benitez
Mar 2
SCL8:55 pmSantiago Arturo Merino Benitez
27h 44m
2 stops
IAH9:39 pmHouston George Bush Intcntl
$763
Find similar
Air Canada
Dec 1
IAH7:10 amHouston George Bush Intcntl
26h 05m
1 stop
SCL12:15 pmSantiago Arturo Merino Benitez
Dec 8
SCL8:55 pmSantiago Arturo Merino Benitez
27h 49m
1 stop
IAH9:44 pmHouston George Bush Intcntl
$1,459
Find similar
Air Canada
Dec 1
IAH7:10 amHouston George Bush Intcntl
26h 05m
1 stop
SCL12:15 pmSantiago Arturo Merino Benitez
Dec 8
SCL8:55 pmSantiago Arturo Merino Benitez
27h 44m
2 stops
IAH9:39 pmHouston George Bush Intcntl
$1,469
Find similar

Delta flights from Houston to Santiago

Our best Delta deals on Houston to Santiago flight tickets
Delta
Feb 2
HOU11:09 amHouston Hobby
21h 26m
2 stops
SCL11:35 amSantiago Arturo Merino Benitez
Feb 16
SCL12:20 amSantiago Arturo Merino Benitez
24h 10m
2 stops
HOU9:30 pmHouston Hobby
$964
Find similar
Delta
May 15
HOU6:00 amHouston Hobby
23h 00m
2 stops
SCL6:00 amSantiago Arturo Merino Benitez
Jun 1
SCL4:55 pmSantiago Arturo Merino Benitez
20h 15m
2 stops
HOU12:10 pmHouston Hobby
$1,004
Find similar
Delta
Dec 26
HOU6:00 amHouston Hobby
21h 10m
1 stop
SCL6:10 amSantiago Arturo Merino Benitez
Jan 18
SCL11:10 pmSantiago Arturo Merino Benitez
20h 00m
1 stop
HOU4:10 pmHouston Hobby
$1,214
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momondo Fare Finder

 
Customize your flight search to find flights from Houston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 21, 2025.
Use the filters below to find and compare flights from Houston to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Mon 12/8

5:00 am-2:40 pm

2 stops30h 40m

Santiago Arturo Merino Benitez

Mon 12/15

6:00 am-11:59 pm

2 stops20h 59m

$556

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Mon 12/8

10:41 am-4:00 am

3 stops38h 19m

Santiago Arturo Merino Benitez

Mon 12/15

6:00 am-11:59 pm

2 stops20h 59m

$573

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Mon 12/8

5:00 am-2:40 pm

2 stops30h 40m

Santiago Arturo Merino Benitez

Mon 12/15

6:00 am-11:59 pm

2 stops20h 59m

$594

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Mon 12/8

10:41 am-4:00 am

3 stops38h 19m

Santiago Arturo Merino Benitez

Mon 12/15

6:00 am-11:59 pm

2 stops20h 59m

$597

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Mon 2/2

11:09 am-11:35 am

2 stops21h 26m

Santiago Arturo Merino Benitez

Tue 2/17

6:30 pm-4:30 pm

2 stops25h 00m

$964

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Thu 1/8

11:09 am-2:30 pm

3 stops24h 21m

Santiago Arturo Merino Benitez

Wed 1/21

6:30 pm-10:21 am

2 stops18h 51m

$969

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Sat 2/14

5:35 pm-5:55 pm

2 stops21h 20m

Santiago Arturo Merino Benitez

Mon 3/2

6:30 pm-10:05 am

2 stops18h 35m

$996

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 5/1

1:00 pm-5:35 am

2 stops15h 35m

Santiago Arturo Merino Benitez

Wed 5/13

6:45 pm-12:10 pm

2 stops18h 25m

$1,001

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 5/15

5:35 pm-2:00 pm

2 stops19h 25m

Santiago Arturo Merino Benitez

Mon 6/1

11:25 pm-9:38 pm

2 stops23h 13m

$1,004

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 5/15

10:05 am-6:00 am

3 stops18h 55m

Santiago Arturo Merino Benitez

Mon 6/1

11:00 pm-9:38 pm

2 stops23h 38m

$1,009

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Houston to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, April is the cheapest month to fly from Houston to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $798. If you don’t want to visit Santiago in April, then you should wait until May to fly from Houston, when ticket prices are also cheap, with an average price of $847.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $1,037. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Sunday is $1,557.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from Houston to Santiago when you can find flight prices for as low as $981. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,499 per ticket.

What is the cheapest Houston to Santiago Arturo Merino Benitez flight route?

Fly from Houston George Bush Intcntl to Santiago Arturo Merino Benitez for the best Houston - Santiago Arturo Merino Benitez flight prices

What cabin class options are available on Houston to Santiago Arturo Merino Benitez flights?

There are 3 cabin classes available to choose from on Houston to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to Santiago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Santiago

Fastest flight time

9h 05m

Direct flights

Every day

Airports in Santiago

1 airport
The fastest flight from Houston to Santiago takes 9h 05m
Direct flights go from Houston to Santiago every day.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)
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  • How far is Houston to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Houston to Santiago Arturo Merino Benitez is 4652.9 mi. A reasonable flight in good conditions will take 12h 28m.

  • When did momondo last update prices for flights from Houston to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Houston to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Houston to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Houston to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Santiago

Compare and see reviews for airlines that fly from Houston to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $499Free CancellationRating
6.6
2,477 reviews
Search Avianca flights
United AirlinesPriceFrom $949Free CancellationRating
7.4
9,030 reviews
Search United Airlines flights
DeltaPriceFrom $963Free CancellationRating
7.9
8,003 reviews
Search Delta flights
LATAM AirlinesPriceFrom $963Free CancellationRating
7.5
1,884 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $1,242Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Santiago?

It is quick and easy to find Houston to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Houston to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Houston which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Houston to Santiago?

Once you have performed a search for Houston to Santiago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Houston to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Houston to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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