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Cheap flights from Houston to Santiago from $269

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Santiago departing on 1/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Houston to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:05 am - 2:40 pm
IAH
-
SCL
30h 35m3 stops
Multiple Airlines Logo
1:35 am - 10:56 pm
SCL
-
IAH
24h 21m3 stops
$693Multiple Airlines
Fri, Jan 30 - Thu, Feb 5
Multiple Airlines Logo
5:05 am - 10:34 am
IAH
-
SCL
26h 29m3 stops
Multiple Airlines Logo
12:35 pm - 3:19 pm
SCL
-
IAH
29h 44m3 stops
$697Multiple Airlines
Mon, Feb 2 - Sat, Feb 7
Multiple Airlines Logo
9:40 pm - 4:00 am
IAH
-
SCL
27h 20m2 stops
Multiple Airlines Logo
10:35 am - 11:59 pm
SCL
-
IAH
16h 24m1 stop
$701Multiple Airlines
Mon, Feb 16 - Sun, Mar 1
Multiple Airlines Logo
7:45 am - 2:40 pm
IAH
-
SCL
27h 55m2 stops
Multiple Airlines Logo
1:35 am - 10:56 pm
SCL
-
IAH
24h 21m3 stops
$705Multiple Airlines
Fri, Jan 30 - Thu, Feb 5
Multiple Airlines Logo
5:23 pm - 6:55 am
IAH
-
SCL
12h 32m1 stop
Multiple Airlines Logo
6:10 am - 11:51 pm
SCL
-
IAH
18h 41m2 stops
$707Multiple Airlines
Wed, Apr 8 - Wed, May 6
Delta Logo
5:22 pm - 6:35 pm
HOU
-
SCL
23h 13m2 stops
Delta Logo
8:45 am - 1:28 pm
SCL
-
HOU
30h 43m2 stops
$964Delta
Tue, Mar 17 - Tue, Mar 31
LATAM Airlines Logo
11:44 am - 1:40 pm
HOU
-
SCL
23h 56m3 stops
LATAM Airlines Logo
8:40 pm - 9:37 am
SCL
-
HOU
13h 57m1 stop
$969LATAM Airlines
Wed, Apr 1 - Thu, Apr 30
LATAM Airlines Logo
1:06 pm - 11:25 pm
HOU
-
SCL
31h 19m2 stops
LATAM Airlines Logo
11:10 pm - 12:20 pm
SCL
-
HOU
16h 10m1 stop
$995LATAM Airlines
Tue, Feb 17 - Tue, Feb 24
Delta Logo
6:00 am - 6:00 am
HOU
-
SCL
23h 00m2 stops
Delta Logo
7:45 pm - 4:26 pm
SCL
-
HOU
21h 41m2 stops
$1,004Delta
Fri, May 15 - Mon, Jun 1
American Airlines Logo
12:18 pm - 9:30 am
HOU
-
SCL
18h 12m2 stops
American Airlines Logo
10:15 pm - 9:43 am
SCL
-
HOU
13h 28m1 stop
$1,009American Airlines
Fri, Mar 6 - Mon, Mar 16

LATAM Airlines flights from Houston to Santiago

Our best LATAM Airlines deals on Houston to Santiago flight tickets
LATAM Airlines
Feb 18
IAH7:05 amHouston George Bush Intcntl
21h 35m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Mar 9
SCL10:10 pmSantiago Arturo Merino Benitez
14h 20m
1 stop
IAH10:30 amHouston George Bush Intcntl
$964
Find similar
LATAM Airlines
Mar 4
HOU5:19 pmHouston Hobby
17h 46m
2 stops
SCL2:05 pmSantiago Arturo Merino Benitez
Mar 17
SCL10:10 pmSantiago Arturo Merino Benitez
17h 18m
1 stop
HOU1:28 pmHouston Hobby
$965
Find similar
LATAM Airlines
May 15
IAH11:50 amHouston George Bush Intcntl
16h 45m
2 stops
SCL5:35 amSantiago Arturo Merino Benitez
Jun 1
SCL11:00 pmSantiago Arturo Merino Benitez
20h 57m
2 stops
IAH6:57 pmHouston George Bush Intcntl
$966
Find similar

Avianca flights from Houston to Santiago

Our best Avianca deals on Houston to Santiago flight tickets
Avianca
Feb 18
IAH4:35 pmHouston George Bush Intcntl
28h 55m
2 stops
SCL12:30 amSantiago Arturo Merino Benitez
Mar 8
SCL4:25 pmSantiago Arturo Merino Benitez
25h 45m
2 stops
IAH4:10 pmHouston George Bush Intcntl
$903
Find similar
Avianca
Feb 15
IAH1:00 pmHouston George Bush Intcntl
23h 20m
2 stops
SCL3:20 pmSantiago Arturo Merino Benitez
Mar 1
SCL4:25 pmSantiago Arturo Merino Benitez
25h 45m
2 stops
IAH3:10 pmHouston George Bush Intcntl
$904
Find similar
Avianca
Mar 6
IAH4:35 pmHouston George Bush Intcntl
33h 55m
2 stops
SCL5:30 amSantiago Arturo Merino Benitez
Mar 15
SCL1:35 amSantiago Arturo Merino Benitez
16h 35m
2 stops
IAH4:10 pmHouston George Bush Intcntl
$920
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Houston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 2, 2026.
Use the filters below to find and compare flights from Houston to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Fri 1/30

5:05 am-2:40 pm

3 stops30h 35m

Santiago Arturo Merino Benitez

Thu 2/5

1:35 am-10:56 pm

3 stops24h 21m

$693

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Mon 2/2

5:05 am-10:34 am

3 stops26h 29m

Santiago Arturo Merino Benitez

Sat 2/7

12:35 pm-3:19 pm

3 stops29h 44m

$697

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Mon 2/16

9:40 pm-4:00 am

2 stops27h 20m

Santiago Arturo Merino Benitez

Sun 3/1

10:35 am-11:59 pm

1 stop16h 24m

$701

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Fri 1/30

7:45 am-2:40 pm

2 stops27h 55m

Santiago Arturo Merino Benitez

Thu 2/5

1:35 am-10:56 pm

3 stops24h 21m

$705

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Wed 4/8

5:23 pm-6:55 am

1 stop12h 32m

Santiago Arturo Merino Benitez

Wed 5/6

6:10 am-11:51 pm

2 stops18h 41m

$707

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Tue 3/17

5:22 pm-6:35 pm

2 stops23h 13m

Santiago Arturo Merino Benitez

Tue 3/31

8:45 am-1:28 pm

2 stops30h 43m

$964

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Wed 4/1

11:44 am-1:40 pm

3 stops23h 56m

Santiago Arturo Merino Benitez

Thu 4/30

8:40 pm-9:37 am

1 stop13h 57m

$969

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Tue 2/17

1:06 pm-11:25 pm

2 stops31h 19m

Santiago Arturo Merino Benitez

Tue 2/24

11:10 pm-12:20 pm

1 stop16h 10m

$995

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 5/15

6:00 am-6:00 am

2 stops23h 00m

Santiago Arturo Merino Benitez

Mon 6/1

7:45 pm-4:26 pm

2 stops21h 41m

$1,004

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 3/6

12:18 pm-9:30 am

2 stops18h 12m

Santiago Arturo Merino Benitez

Mon 3/16

10:15 pm-9:43 am

1 stop13h 28m

$1,009

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Houston to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Houston and Santiago?

What is the cheapest month to fly to Santiago?

In general, April is the cheapest month to fly from Houston to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $720. If you don’t want to visit Santiago in April, then you should wait until May to fly from Houston, when ticket prices are also cheap, with an average price of $847.

What is the cheapest Houston to Santiago Arturo Merino Benitez flight route?

Fly from Houston George Bush Intcntl to Santiago Arturo Merino Benitez for the best Houston - Santiago Arturo Merino Benitez flight prices

What cabin class options are available on Houston to Santiago Arturo Merino Benitez flights?

There are 3 cabin classes available to choose from on Houston to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to Santiago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Santiago

Fastest flight time

9h 05m

Direct flights

Every day

Airports in Santiago

1 airport
The fastest flight from Houston to Santiago takes 9h 05m
Direct flights go from Houston to Santiago every day.
There is 1 airport in Santiago. From Houston there are direct flights to Santiago Arturo Merino Benitez (SCL).
Search flight deals

  • How far is Houston to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Houston to Santiago Arturo Merino Benitez is 4652.9 mi. A reasonable flight in good conditions will take 9h 05m.

  • When did momondo last update prices for flights from Houston to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Houston to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Houston to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Houston to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Santiago

Compare and see reviews for airlines that fly from Houston to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $548Free CancellationRating
6.6
2,495 reviews
Search Avianca flights
LATAM AirlinesPriceFrom $949Free CancellationRating
7.5
1,899 reviews
Search LATAM Airlines flights
United AirlinesPriceFrom $949Free CancellationRating
7.4
9,128 reviews
Search United Airlines flights
American AirlinesPriceFrom $964Free CancellationRating
7.2
11,075 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Santiago?

It is quick and easy to find Houston to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Houston to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Houston which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Houston to Santiago?

Once you have performed a search for Houston to Santiago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Houston to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Houston to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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