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Cheap flights from Houston to Santiago from $246

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Santiago departing on 5/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Houston to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:24 pm - 8:15 am
IAH
-
SCL
35h 51m2 stops
Multiple Airlines Logo
10:35 am - 10:36 am
SCL
-
IAH
26h 01m2 stops
$638Multiple Airlines
Thu, Mar 5 - Fri, Mar 13
Multiple Airlines Logo
5:24 pm - 8:15 am
IAH
-
SCL
35h 51m2 stops
Multiple Airlines Logo
10:35 am - 10:36 am
SCL
-
IAH
26h 01m2 stops
$639Multiple Airlines
Thu, Mar 5 - Fri, Mar 13
Multiple Airlines Logo
6:30 am - 5:30 am
IAH
-
SCL
44h 00m2 stops
Multiple Airlines Logo
10:35 am - 11:59 pm
SCL
-
IAH
15h 24m1 stop
$668Multiple Airlines
Tue, Mar 3 - Wed, Mar 11
LATAM Airlines Logo
5:19 pm - 2:05 pm
HOU
-
SCL
17h 46m2 stops
LATAM Airlines Logo
12:20 am - 10:42 pm
SCL
-
HOU
24h 22m2 stops
$965LATAM Airlines
Tue, Mar 3 - Mon, Mar 23
LATAM Airlines Logo
1:45 pm - 7:15 am
HOU
-
SCL
16h 30m1 stop
LATAM Airlines Logo
8:40 pm - 9:37 am
SCL
-
HOU
13h 57m1 stop
$987LATAM Airlines
Thu, Apr 16 - Thu, Apr 30
LATAM Airlines Logo
10:35 am - 6:00 am
HOU
-
SCL
18h 25m2 stops
LATAM Airlines Logo
8:40 pm - 9:20 am
SCL
-
HOU
13h 40m1 stop
$997LATAM Airlines
Fri, May 1 - Wed, May 13
LATAM Airlines Logo
1:45 pm - 6:55 am
HOU
-
SCL
16h 10m2 stops
LATAM Airlines Logo
6:45 pm - 12:10 pm
SCL
-
HOU
18h 25m2 stops
$1,002LATAM Airlines
Fri, May 1 - Wed, May 13
Delta Logo
10:50 am - 7:40 am
HOU
-
SCL
17h 50m1 stop
Delta Logo
1:35 am - 10:42 pm
SCL
-
HOU
23h 07m2 stops
$1,005Delta
Thu, Mar 5 - Thu, Mar 12
Delta Logo
5:25 am - 6:55 am
HOU
-
SCL
22h 30m2 stops
Delta Logo
8:05 am - 3:43 pm
SCL
-
HOU
33h 38m2 stops
$1,010Delta
Thu, Mar 5 - Fri, Mar 13
Delta Logo
10:05 am - 2:05 pm
HOU
-
SCL
27h 00m2 stops
Delta Logo
8:40 pm - 4:26 pm
SCL
-
HOU
20h 46m1 stop
$1,045Delta
Sun, May 24 - Sun, May 31

LATAM Airlines flights from Houston to Santiago

Our best LATAM Airlines deals on Houston to Santiago flight tickets
LATAM Airlines
Mar 3
HOU5:19 pmHouston Hobby
17h 46m
2 stops
SCL2:05 pmSantiago Arturo Merino Benitez
Mar 23
SCL12:20 amSantiago Arturo Merino Benitez
24h 22m
2 stops
HOU10:42 pmHouston Hobby
$965
Find similar
LATAM Airlines
Apr 16
HOU1:45 pmHouston Hobby
16h 30m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
Apr 30
SCL8:40 pmSantiago Arturo Merino Benitez
13h 57m
1 stop
HOU9:37 amHouston Hobby
$987
Find similar
LATAM Airlines
May 1
HOU10:35 amHouston Hobby
18h 25m
2 stops
SCL6:00 amSantiago Arturo Merino Benitez
May 13
SCL8:40 pmSantiago Arturo Merino Benitez
13h 40m
1 stop
HOU9:20 amHouston Hobby
$997
Find similar

Delta flights from Houston to Santiago

Our best Delta deals on Houston to Santiago flight tickets
Delta
Mar 5
HOU10:50 amHouston Hobby
17h 50m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Mar 12
SCL1:35 amSantiago Arturo Merino Benitez
23h 07m
2 stops
HOU10:42 pmHouston Hobby
$1,005
Find similar
Delta
Mar 5
HOU5:25 amHouston Hobby
22h 30m
2 stops
SCL6:55 amSantiago Arturo Merino Benitez
Mar 13
SCL8:05 amSantiago Arturo Merino Benitez
33h 38m
2 stops
HOU3:43 pmHouston Hobby
$1,010
Find similar
Delta
May 24
HOU10:05 amHouston Hobby
27h 00m
2 stops
SCL2:05 pmSantiago Arturo Merino Benitez
May 31
SCL8:40 pmSantiago Arturo Merino Benitez
20h 46m
1 stop
HOU4:26 pmHouston Hobby
$1,045
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Houston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 6, 2026.
Use the filters below to find and compare flights from Houston to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Thu 3/5

5:24 pm-8:15 am

2 stops35h 51m

Santiago Arturo Merino Benitez

Fri 3/13

10:35 am-10:36 am

2 stops26h 01m

$638

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Thu 3/5

5:24 pm-8:15 am

2 stops35h 51m

Santiago Arturo Merino Benitez

Fri 3/13

10:35 am-10:36 am

2 stops26h 01m

$639

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Tue 3/3

6:30 am-5:30 am

2 stops44h 00m

Santiago Arturo Merino Benitez

Wed 3/11

10:35 am-11:59 pm

1 stop15h 24m

$668

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Tue 3/3

5:19 pm-2:05 pm

2 stops17h 46m

Santiago Arturo Merino Benitez

Mon 3/23

12:20 am-10:42 pm

2 stops24h 22m

$965

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Thu 4/16

1:45 pm-7:15 am

1 stop16h 30m

Santiago Arturo Merino Benitez

Thu 4/30

8:40 pm-9:37 am

1 stop13h 57m

$987

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 5/1

10:35 am-6:00 am

2 stops18h 25m

Santiago Arturo Merino Benitez

Wed 5/13

8:40 pm-9:20 am

1 stop13h 40m

$997

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 5/1

1:45 pm-6:55 am

2 stops16h 10m

Santiago Arturo Merino Benitez

Wed 5/13

6:45 pm-12:10 pm

2 stops18h 25m

$1,002

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Thu 3/5

10:50 am-7:40 am

1 stop17h 50m

Santiago Arturo Merino Benitez

Thu 3/12

1:35 am-10:42 pm

2 stops23h 07m

$1,005

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Thu 3/5

5:25 am-6:55 am

2 stops22h 30m

Santiago Arturo Merino Benitez

Fri 3/13

8:05 am-3:43 pm

2 stops33h 38m

$1,010

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Sun 5/24

10:05 am-2:05 pm

2 stops27h 00m

Santiago Arturo Merino Benitez

Sun 5/31

8:40 pm-4:26 pm

1 stop20h 46m

$1,045

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Houston to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Houston and Santiago?

What is the cheapest month to fly to Santiago?

In general, April is the cheapest month to fly from Houston to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $720. If you don’t want to visit Santiago in April, then you should wait until May to fly from Houston, when ticket prices are also cheap, with an average price of $847.

What is the cheapest Houston to Santiago Arturo Merino Benitez flight route?

Fly from Houston George Bush Intcntl to Santiago Arturo Merino Benitez for the best Houston - Santiago Arturo Merino Benitez flight prices

What cabin class options are available on Houston to Santiago Arturo Merino Benitez flights?

There are 3 cabin classes available to choose from on Houston to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to Santiago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Santiago

Fastest flight time

9h 05m

Direct flights

Every day

Airports in Santiago

1 airport
The fastest flight from Houston to Santiago takes 9h 05m
Direct flights go from Houston to Santiago every day.
There is 1 airport in Santiago. From Houston there are direct flights to Santiago Arturo Merino Benitez (SCL).
Search flight deals

  • How far is Houston to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Houston to Santiago Arturo Merino Benitez is 4652.9 mi. A reasonable flight in good conditions will take 9h 05m.

  • When did momondo last update prices for flights from Houston to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Houston to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Houston to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Houston to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Santiago

Compare and see reviews for airlines that fly from Houston to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $548Free CancellationRating
6.6
2,498 reviews
Search Avianca flights
LATAM AirlinesPriceFrom $949Free CancellationRating
7.5
1,901 reviews
Search LATAM Airlines flights
United AirlinesPriceFrom $949Free CancellationRating
7.4
9,134 reviews
Search United Airlines flights
American AirlinesPriceFrom $964Free CancellationRating
7.2
11,083 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Santiago?

It is quick and easy to find Houston to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Houston to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Houston which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Houston to Santiago?

Once you have performed a search for Houston to Santiago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Houston to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Houston to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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