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Cheap flights from Houston to Santiago from $252

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Santiago departing on 2/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:35 pm - 5:50 amIAH-SCL
30h 15m2 stops
Multiple Airlines Logo
9:05 pm - 7:30 pmSCL-IAH
25h 25m2 stops
$559Multiple Airlines
Find Deal
mar., nov. 4 - mié., nov. 12
Multiple Airlines Logo
8:35 pm - 10:15 pmIAH-SCL
22h 40m2 stops
Multiple Airlines Logo
1:35 am - 5:26 pmSCL-IAH
18h 51m2 stops
$566Multiple Airlines
Find Deal
mar., nov. 4 - mar., nov. 11
Multiple Airlines Logo
11:10 pm - 10:15 pmIAH-SCL
44h 05m3 stops
Multiple Airlines Logo
12:30 pm - 7:30 pmSCL-IAH
34h 00m2 stops
$568Multiple Airlines
Find Deal
dom., nov. 9 - vie., nov. 14
Air Canada Logo
11:50 am - 7:00 amIAH-SCL
16h 10m1 stop
Air Canada Logo
8:55 pm - 9:44 pmSCL-IAH
27h 49m1 stop
$691Air Canada
Find Deal
mar., ene. 27 - mar., feb. 10
Delta Logo
5:00 pm - 2:05 pmHOU-SCL
18h 05m2 stops
Delta Logo
11:15 pm - 9:32 amSCL-HOU
13h 17m1 stop
$957Delta
Find Deal
lun., ene. 12 - mié., ene. 28
Delta Logo
5:00 pm - 3:30 pmHOU-SCL
19h 30m2 stops
Delta Logo
6:30 pm - 9:32 amSCL-HOU
18h 02m2 stops
$964Delta
Find Deal
lun., feb. 2 - mar., feb. 17
LATAM Airlines Logo
3:25 pm - 2:05 pmHOU-SCL
19h 40m2 stops
LATAM Airlines Logo
11:15 pm - 9:32 amSCL-HOU
13h 17m1 stop
$996LATAM Airlines
Find Deal
sáb., dic. 27 - lun., feb. 2
LATAM Airlines Logo
10:30 am - 7:00 amHOU-SCL
17h 30m1 stop
LATAM Airlines Logo
11:15 pm - 3:02 pmSCL-HOU
18h 47m1 stop
$1,036LATAM Airlines
Find Deal
vie., ene. 30 - vie., feb. 20
American Airlines Logo
4:55 pm - 7:50 amHOU-SCL
11h 55m1 stop
American Airlines Logo
11:15 pm - 10:05 amSCL-HOU
13h 50m1 stop
$1,037American Airlines
Find Deal
vie., ene. 9 - sáb., ene. 31
American Airlines Logo
9:02 am - 7:45 amHOU-SCL
19h 43m1 stop
American Airlines Logo
11:15 pm - 11:45 amSCL-HOU
15h 30m1 stop
$1,089American Airlines
Find Deal
mié., dic. 3 - mié., dic. 10

Air Canada flights from Houston to Santiago

Our best Air Canada deals on Houston to Santiago flight tickets
Air Canada
Jan 27
IAH11:50 amHouston George Bush Intcntl
16h 10m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Feb 10
SCL8:55 pmSantiago Arturo Merino Benitez
27h 49m
1 stop
IAH9:44 pmHouston George Bush Intcntl
$691
Find similar
Air Canada
Oct 27
IAH7:10 amHouston George Bush Intcntl
26h 05m
1 stop
SCL11:15 amSantiago Arturo Merino Benitez
Nov 5
SCL8:55 pmSantiago Arturo Merino Benitez
17h 14m
1 stop
IAH11:09 amHouston George Bush Intcntl
$698
Find similar

Delta flights from Houston to Santiago

Our best Delta deals on Houston to Santiago flight tickets
Delta
Jan 12
HOU5:00 pmHouston Hobby
18h 05m
2 stops
SCL2:05 pmSantiago Arturo Merino Benitez
Jan 28
SCL11:15 pmSantiago Arturo Merino Benitez
13h 17m
1 stop
HOU9:32 amHouston Hobby
$957
Find similar
Delta
Feb 2
HOU5:00 pmHouston Hobby
19h 30m
2 stops
SCL3:30 pmSantiago Arturo Merino Benitez
Feb 17
SCL6:30 pmSantiago Arturo Merino Benitez
18h 02m
2 stops
HOU9:32 amHouston Hobby
$964
Find similar
Delta
Dec 11
HOU6:00 amHouston Hobby
21h 35m
2 stops
SCL6:35 amSantiago Arturo Merino Benitez
Dec 24
SCL8:15 amSantiago Arturo Merino Benitez
28h 46m
2 stops
HOU10:01 amHouston Hobby
$969
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Houston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated octubre 20, 2025.
Use the filters below to find and compare flights from Houston to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

mar. 11/4

8:35 pm-5:50 am

2 stops30h 15m

Santiago Arturo Merino Benitez

mié. 11/12

9:05 pm-7:30 pm

2 stops25h 25m

$559

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

mar. 11/4

8:35 pm-10:15 pm

2 stops22h 40m

Santiago Arturo Merino Benitez

mar. 11/11

1:35 am-5:26 pm

2 stops18h 51m

$566

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

dom. 11/9

11:10 pm-10:15 pm

3 stops44h 05m

Santiago Arturo Merino Benitez

vie. 11/14

12:30 pm-7:30 pm

2 stops34h 00m

$568

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

mar. 1/27

11:50 am-7:00 am

1 stop16h 10m

Santiago Arturo Merino Benitez

mar. 2/10

8:55 pm-9:44 pm

1 stop27h 49m

$691

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

lun. 1/12

5:00 pm-2:05 pm

2 stops18h 05m

Santiago Arturo Merino Benitez

mié. 1/28

11:15 pm-9:32 am

1 stop13h 17m

$957

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

lun. 2/2

5:00 pm-3:30 pm

2 stops19h 30m

Santiago Arturo Merino Benitez

mar. 2/17

6:30 pm-9:32 am

2 stops18h 02m

$964

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

sáb. 12/27

3:25 pm-2:05 pm

2 stops19h 40m

Santiago Arturo Merino Benitez

lun. 2/2

11:15 pm-9:32 am

1 stop13h 17m

$996

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

vie. 1/30

10:30 am-7:00 am

1 stop17h 30m

Santiago Arturo Merino Benitez

vie. 2/20

11:15 pm-3:02 pm

1 stop18h 47m

$1,036

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

vie. 1/9

4:55 pm-7:50 am

1 stop11h 55m

Santiago Arturo Merino Benitez

sáb. 1/31

11:15 pm-10:05 am

1 stop13h 50m

$1,037

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

mié. 12/3

9:02 am-7:45 am

1 stop19h 43m

Santiago Arturo Merino Benitez

mié. 12/10

11:15 pm-11:45 am

1 stop15h 30m

$1,089

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Houston to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Houston and Santiago?

What is the cheapest month to fly to Santiago?

In general, May is the cheapest month to fly from Houston to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $847. If you don’t want to visit Santiago in May, then you should wait until April to fly from Houston, when ticket prices are also cheap, with an average price of $1,018.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $1,037. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Sunday is $1,557.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from Houston to Santiago when you can find flight prices for as low as $981. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,500 per ticket.

What is the cheapest Houston to Santiago Arturo Merino Benitez flight route?

Fly from Houston George Bush Intcntl to Santiago Arturo Merino Benitez for the best Houston - Santiago Arturo Merino Benitez flight prices

What cabin class options are available on Houston to Santiago Arturo Merino Benitez flights?

There are 3 cabin classes available to choose from on Houston to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to Santiago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Santiago

Fastest flight time

9h 05m

Direct flights

Every day

Airports in Santiago

1 airport
The fastest flight from Houston to Santiago takes 9h 05m
Direct flights go from Houston to Santiago every day.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)
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  • How far is Houston to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Houston to Santiago Arturo Merino Benitez is 4652.9 mi. A reasonable flight in good conditions will take 11h 55m.

  • When did momondo last update prices for flights from Houston to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Houston to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Houston to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Houston to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Santiago

Compare and see reviews for airlines that fly from Houston to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $499Free CancellationRating
6.6
2,457 reviews
Search Avianca flights
United AirlinesPriceFrom $949Free CancellationRating
7.4
8,993 reviews
Search United Airlines flights
DeltaPriceFrom $963Free CancellationRating
7.9
7,978 reviews
Search Delta flights
LATAM AirlinesPriceFrom $963Free CancellationRating
7.5
1,868 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $1,242Free CancellationRating
7.2
11,026 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Santiago?

It is quick and easy to find Houston to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Houston to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Houston which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Houston to Santiago?

Once you have performed a search for Houston to Santiago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Houston to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Houston to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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