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Cheap flights from Greenville to Santo Domingo from $383

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Santo Domingo departing on 7/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Greenville to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
10:24 am - 5:23 pm
GSP
-
SDQ
5h 59m
1 stop
American Airlines Logo
4:59 pm - 11:57 pm
SDQ
-
GSP
7h 58m
1 stop
$550American Airlines
Wed, Nov 18 - Wed, Nov 25
American Airlines Logo
5:25 am - 3:55 pm
GSP
-
SDQ
9h 30m
2 stops
American Airlines Logo
6:00 am - 3:56 pm
SDQ
-
GSP
10h 56m
2 stops
$555American Airlines
Wed, Nov 18 - Wed, Nov 25
American Airlines Logo
8:00 pm - 9:27 am
GSP
-
SDQ
13h 27m
1 stop
American Airlines Logo
2:00 pm - 10:24 am
SDQ
-
GSP
20h 24m
1 stop
$559American Airlines
Thu, Jul 30 - Thu, Aug 6
American Airlines Logo
10:37 am - 9:25 pm
GSP
-
SDQ
10h 48m
2 stops
American Airlines Logo
2:00 pm - 2:41 pm
SDQ
-
GSP
24h 41m
1 stop
$563American Airlines
Thu, Jul 30 - Thu, Aug 6
American Airlines Logo
6:00 am - 6:44 pm
GSP
-
SDQ
12h 44m
1 stop
American Airlines Logo
10:27 am - 10:58 pm
SDQ
-
GSP
12h 31m
1 stop
$570American Airlines
Thu, Aug 20 - Sat, Aug 29
American Airlines Logo
6:28 am - 6:44 pm
GSP
-
SDQ
12h 16m
2 stops
American Airlines Logo
10:27 am - 10:58 pm
SDQ
-
GSP
12h 31m
1 stop
$575American Airlines
Thu, Aug 20 - Sat, Aug 29
American Airlines Logo
4:08 pm - 9:22 am
GSP
-
SDQ
17h 14m
1 stop
American Airlines Logo
10:27 am - 11:58 pm
SDQ
-
GSP
13h 31m
1 stop
$599American Airlines
Sat, Oct 10 - Mon, Oct 12
American Airlines Logo
10:37 am - 9:25 pm
GSP
-
SDQ
10h 48m
2 stops
American Airlines Logo
4:24 pm - 10:28 am
SDQ
-
GSP
18h 04m
2 stops
$600American Airlines
Thu, Jul 30 - Thu, Aug 6
American Airlines Logo
8:00 pm - 9:27 am
GSP
-
SDQ
13h 27m
1 stop
American Airlines Logo
2:00 pm - 10:24 am
SDQ
-
GSP
20h 24m
1 stop
$604American Airlines
Wed, Jul 22 - Wed, Aug 5
American Airlines Logo
10:37 am - 9:25 pm
GSP
-
SDQ
10h 48m
2 stops
American Airlines Logo
2:00 pm - 2:41 pm
SDQ
-
GSP
24h 41m
1 stop
$608American Airlines
Wed, Jul 22 - Wed, Aug 5

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Delta flights from Greenville to Santo Domingo

Our best Delta deals on Greenville to Santo Domingo flight tickets
Delta
Dec 24
GSP3:00 pmGreenville
10h 20m
1 stop
SDQ2:20 amSanto Domingo Las Americas
Dec 30
SDQ3:45 amSanto Domingo Las Americas
11h 34m
1 stop
GSP2:19 pmGreenville
$794
Delta
Jul 20
GSP7:44 pmGreenville
22h 22m
2 stops
SDQ6:06 pmSanto Domingo Las Americas
Jul 30
SDQ7:35 pmSanto Domingo Las Americas
24h 40m
2 stops
GSP8:15 pmGreenville
$805
Delta
Dec 24
GSP3:00 pmGreenville
10h 20m
1 stop
SDQ2:20 amSanto Domingo Las Americas
Dec 30
SDQ3:45 amSanto Domingo Las Americas
19h 17m
2 stops
GSP10:02 pmGreenville
$833

United Airlines flights from Greenville to Santo Domingo

Our best United Airlines deals on Greenville to Santo Domingo flight tickets
United Airlines
Oct 14
GSP6:00 amGreenville
8h 10m
1 stop
SDQ2:10 pmSanto Domingo Las Americas
Oct 22
SDQ3:20 pmSanto Domingo Las Americas
7h 39m
1 stop
GSP10:59 pmGreenville
$740
United Airlines
Jul 20
GSP6:30 amGreenville
16h 16m
1 stop
SDQ10:46 pmSanto Domingo Las Americas
Jul 28
SDQ6:00 amSanto Domingo Las Americas
17h 13m
1 stop
GSP11:13 pmGreenville
$755
United Airlines
Jul 20
GSP6:30 amGreenville
16h 16m
1 stop
SDQ10:46 pmSanto Domingo Las Americas
Jul 24
SDQ6:00 amSanto Domingo Las Americas
13h 08m
1 stop
GSP7:08 pmGreenville
$830

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 1, 2026.
Use the filters below to find and compare flights from Greenville to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Wed 11/18

10:24 am-5:23 pm

1 stop5h 59m

Santo Domingo Las Americas

Wed 11/25

4:59 pm-11:57 pm

1 stop7h 58m

$550

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Wed 11/18

5:25 am-3:55 pm

2 stops9h 30m

Santo Domingo Las Americas

Wed 11/25

6:00 am-3:56 pm

2 stops10h 56m

$555

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Thu 7/30

8:00 pm-9:27 am

1 stop13h 27m

Santo Domingo Las Americas

Thu 8/6

2:00 pm-10:24 am

1 stop20h 24m

$559

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Thu 7/30

10:37 am-9:25 pm

2 stops10h 48m

Santo Domingo Las Americas

Thu 8/6

2:00 pm-2:41 pm

1 stop24h 41m

$563

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Thu 8/20

6:00 am-6:44 pm

1 stop12h 44m

Santo Domingo Las Americas

Sat 8/29

10:27 am-10:58 pm

1 stop12h 31m

$570

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Thu 8/20

6:28 am-6:44 pm

2 stops12h 16m

Santo Domingo Las Americas

Sat 8/29

10:27 am-10:58 pm

1 stop12h 31m

$575

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Sat 10/10

4:08 pm-9:22 am

1 stop17h 14m

Santo Domingo Las Americas

Mon 10/12

10:27 am-11:58 pm

1 stop13h 31m

$599

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Thu 7/30

10:37 am-9:25 pm

2 stops10h 48m

Santo Domingo Las Americas

Thu 8/6

4:24 pm-10:28 am

2 stops18h 04m

$600

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Wed 7/22

8:00 pm-9:27 am

1 stop13h 27m

Santo Domingo Las Americas

Wed 8/5

2:00 pm-10:24 am

1 stop20h 24m

$604

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Wed 7/22

10:37 am-9:25 pm

2 stops10h 48m

Santo Domingo Las Americas

Wed 8/5

2:00 pm-2:41 pm

1 stop24h 41m

$608

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Greenville to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Greenville and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in September, then you should wait until November to fly from Greenville, when ticket prices are also cheap, with an average price of $517.

Can stopping save me money on Greenville to Santo Domingo flights?

You could potentially save up to 6% on your flight if you consider stops on a Greenville to Santo Domingo flight.

When to book flights from Greenville to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Santo Domingo (GSP to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Santo Domingo

Fastest flight time

5h 52m

Direct flights

None
The fastest flight from Greenville to Santo Domingo takes 5h 52m
There are no direct flights from Greenville to Santo Domingo. There are no popular flight routes from Greenville to Santo Domingo.
Search flight deals

Frequently asked questions about flying from Greenville to Santo Domingo

  • How far is Greenville to Santo Domingo Las Americas by plane?

    Santo Domingo Las Americas is 1364.2 mi away from Greenville. Flights usually cover this in 5h 52m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Greenville Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Greenville Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Greenville Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents you'll need for your trip to Santo Domingo Las Americas Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santo Domingo Las Americas Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to Santo Domingo?

Best airlines flying from Greenville to Santo Domingo

Compare and see reviews for airlines that fly from Greenville to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $488Free CancellationRating
7.1
11,766 reviews
Search American Airlines flights
DeltaPriceFrom $499Free CancellationRating
7.8
8,452 reviews
Search Delta flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Santo Domingo?

It is quick and easy to find Greenville to Santo Domingo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santo Domingo that suits you.

Can I find flights from Greenville to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from Greenville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Greenville to Santo Domingo?

momondo helps you find the best flight between Greenville and Santo Domingo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to Santo Domingo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santo Domingo from Greenville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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