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Cheap flights from Greenville to Santo Domingo from $209

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Santo Domingo departing on 5/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Greenville to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
4:10 pm - 5:29 am
GSP
-
SDQ
37h 19m
2 stops
Multiple Airlines Logo
4:01 pm - 12:32 pm
SDQ
-
GSP
20h 31m
1 stop
$518Multiple Airlines
Fri, May 29 - Sun, Jun 7
American Airlines Logo
8:35 pm - 9:24 am
GSP
-
SDQ
12h 49m
1 stop
American Airlines Logo
7:00 am - 7:45 pm
SDQ
-
GSP
12h 45m
1 stop
$539American Airlines
Sat, Jun 6 - Wed, Jun 10
American Airlines Logo
8:35 pm - 9:24 am
GSP
-
SDQ
12h 49m
1 stop
American Airlines Logo
10:25 am - 10:38 pm
SDQ
-
GSP
12h 13m
2 stops
$543American Airlines
Sat, Jun 6 - Wed, Jun 10
American Airlines Logo
8:15 pm - 9:24 am
GSP
-
SDQ
13h 09m
1 stop
American Airlines Logo
7:00 am - 7:45 pm
SDQ
-
GSP
12h 45m
1 stop
$559American Airlines
Thu, May 28 - Fri, Jun 5
American Airlines Logo
10:33 am - 10:55 pm
GSP
-
SDQ
12h 22m
2 stops
American Airlines Logo
7:00 am - 9:15 pm
SDQ
-
GSP
14h 15m
2 stops
$563American Airlines
Thu, May 28 - Fri, Jun 5
American Airlines Logo
8:35 pm - 9:24 am
GSP
-
SDQ
12h 49m
1 stop
American Airlines Logo
1:45 pm - 10:50 am
SDQ
-
GSP
21h 05m
1 stop
$573American Airlines
Sat, May 30 - Sun, Jun 7
American Airlines Logo
7:32 pm - 9:24 am
GSP
-
SDQ
13h 52m
2 stops
American Airlines Logo
1:45 pm - 10:50 am
SDQ
-
GSP
21h 05m
1 stop
$577American Airlines
Sat, May 30 - Sun, Jun 7
American Airlines Logo
8:35 pm - 9:24 am
GSP
-
SDQ
12h 49m
1 stop
American Airlines Logo
7:35 pm - 11:42 am
SDQ
-
GSP
16h 07m
1 stop
$579American Airlines
Sat, Jun 20 - Fri, Jun 26
American Airlines Logo
7:32 pm - 9:24 am
GSP
-
SDQ
13h 52m
2 stops
American Airlines Logo
7:35 pm - 11:42 am
SDQ
-
GSP
16h 07m
1 stop
$583American Airlines
Sat, Jun 20 - Fri, Jun 26
United Airlines Logo
6:00 am - 2:10 pm
GSP
-
SDQ
8h 10m
1 stop
United Airlines Logo
1:10 pm - 11:05 pm
SDQ
-
GSP
9h 55m
1 stop
$584United Airlines
Fri, May 8 - Fri, May 15

United Airlines flights from Greenville to Santo Domingo

Our best United Airlines deals on Greenville to Santo Domingo flight tickets
United Airlines
May 8
GSP6:00 amGreenville
8h 10m
1 stop
SDQ2:10 pmSanto Domingo Las Americas
May 15
SDQ1:10 pmSanto Domingo Las Americas
9h 55m
1 stop
GSP11:05 pmGreenville
$584
United Airlines
May 25
GSP6:30 amGreenville
7h 40m
1 stop
SDQ2:10 pmSanto Domingo Las Americas
May 29
SDQ3:20 pmSanto Domingo Las Americas
8h 09m
1 stop
GSP11:29 pmGreenville
$799
United Airlines
May 26
GSP6:30 amGreenville
7h 40m
1 stop
SDQ2:10 pmSanto Domingo Las Americas
May 31
SDQ3:20 pmSanto Domingo Las Americas
8h 09m
1 stop
GSP11:29 pmGreenville
$839

American Airlines flights from Greenville to Santo Domingo

Our best American Airlines deals on Greenville to Santo Domingo flight tickets
American Airlines
Jun 6
GSP8:35 pmGreenville
12h 49m
1 stop
SDQ9:24 amSanto Domingo Las Americas
Jun 10
SDQ7:00 amSanto Domingo Las Americas
12h 45m
1 stop
GSP7:45 pmGreenville
$539
American Airlines
Jun 6
GSP8:35 pmGreenville
12h 49m
1 stop
SDQ9:24 amSanto Domingo Las Americas
Jun 10
SDQ10:25 amSanto Domingo Las Americas
12h 13m
2 stops
GSP10:38 pmGreenville
$543
American Airlines
May 28
GSP8:15 pmGreenville
13h 09m
1 stop
SDQ9:24 amSanto Domingo Las Americas
Jun 5
SDQ7:00 amSanto Domingo Las Americas
12h 45m
1 stop
GSP7:45 pmGreenville
$559

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 29, 2026.
Use the filters below to find and compare flights from Greenville to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Fri 5/29

4:10 pm-5:29 am

2 stops37h 19m

Santo Domingo Las Americas

Sun 6/7

4:01 pm-12:32 pm

1 stop20h 31m

$518

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Sat 6/6

8:35 pm-9:24 am

1 stop12h 49m

Santo Domingo Las Americas

Wed 6/10

7:00 am-7:45 pm

1 stop12h 45m

$539

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Sat 6/6

8:35 pm-9:24 am

1 stop12h 49m

Santo Domingo Las Americas

Wed 6/10

10:25 am-10:38 pm

2 stops12h 13m

$543

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Thu 5/28

8:15 pm-9:24 am

1 stop13h 09m

Santo Domingo Las Americas

Fri 6/5

7:00 am-7:45 pm

1 stop12h 45m

$559

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Thu 5/28

10:33 am-10:55 pm

2 stops12h 22m

Santo Domingo Las Americas

Fri 6/5

7:00 am-9:15 pm

2 stops14h 15m

$563

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Sat 5/30

8:35 pm-9:24 am

1 stop12h 49m

Santo Domingo Las Americas

Sun 6/7

1:45 pm-10:50 am

1 stop21h 05m

$573

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Sat 5/30

7:32 pm-9:24 am

2 stops13h 52m

Santo Domingo Las Americas

Sun 6/7

1:45 pm-10:50 am

1 stop21h 05m

$577

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Sat 6/20

8:35 pm-9:24 am

1 stop12h 49m

Santo Domingo Las Americas

Fri 6/26

7:35 pm-11:42 am

1 stop16h 07m

$579

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Sat 6/20

7:32 pm-9:24 am

2 stops13h 52m

Santo Domingo Las Americas

Fri 6/26

7:35 pm-11:42 am

1 stop16h 07m

$583
Quickest round-trip

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Fri 5/8

6:00 am-2:10 pm

1 stop8h 10m

Santo Domingo Las Americas

Fri 5/15

1:10 pm-11:05 pm

1 stop9h 55m

$584

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Greenville to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Greenville and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in May, then you should wait until March to fly from Greenville, when ticket prices are also cheap, with an average price of $489.

Can stopping save me money on Greenville to Santo Domingo flights?

You could potentially save up to 5% on your flight if you consider stops on a Greenville to Santo Domingo flight.

When to book flights from Greenville to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Santo Domingo (GSP to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Santo Domingo

Fastest flight time

6h 56m

Direct flights

None
The fastest flight from Greenville to Santo Domingo takes 6h 56m
There are no direct flights from Greenville to Santo Domingo. There are no popular flight routes from Greenville to Santo Domingo.
Search flight deals

  • How far is Greenville to Santo Domingo Las Americas by plane?

    Santo Domingo Las Americas is 1364.2 mi away from Greenville. Flights usually cover this in 6h 56m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Greenville Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Greenville Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Greenville Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents you'll need for your trip to Santo Domingo Las Americas Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santo Domingo Las Americas Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to Santo Domingo?

Best airlines flying from Greenville to Santo Domingo

Compare and see reviews for airlines that fly from Greenville to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $484Free CancellationRating
7.9
8,359 reviews
Search Delta flights
American AirlinesPriceFrom $488Free CancellationRating
7.1
11,521 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Santo Domingo?

It is quick and easy to find Greenville to Santo Domingo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santo Domingo that suits you.

Can I find flights from Greenville to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from Greenville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Greenville to Santo Domingo?

momondo helps you find the best flight between Greenville and Santo Domingo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to Santo Domingo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santo Domingo from Greenville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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