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Cheap flights from Greenville to Santo Domingo from $467

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Santo Domingo departing on 11/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Greenville to Santo Domingo

Cheap round-trip flights

Delta Logo
5:30 am - 2:41 pmGSP-SDQ
8h 11m1 stop
Delta Logo
3:57 pm - 9:25 pmSDQ-GSP
6h 28m1 stop
$467Delta
Find Deal
Wed, Nov 5 - Wed, Nov 12
Delta Logo
5:30 am - 2:41 pmGSP-SDQ
8h 11m1 stop
Delta Logo
6:45 am - 4:31 pmSDQ-GSP
10h 46m2 stops
$472Delta
Find Deal
Wed, Nov 5 - Wed, Nov 12
American Airlines Logo
4:46 pm - 1:35 pmGSP-SDQ
20h 49m1 stop
American Airlines Logo
10:25 am - 11:21 pmSDQ-GSP
12h 56m1 stop
$477American Airlines
Find Deal
Thu, Oct 23 - Wed, Oct 29
American Airlines Logo
4:46 pm - 1:35 pmGSP-SDQ
20h 49m1 stop
American Airlines Logo
10:25 am - 8:24 pmSDQ-GSP
9h 59m2 stops
$481American Airlines
Find Deal
Thu, Oct 23 - Wed, Oct 29
Delta Logo
5:30 am - 7:24 pmGSP-SDQ
12h 54m2 stops
Delta Logo
6:45 am - 6:09 pmSDQ-GSP
12h 24m2 stops
$482Delta
Find Deal
Thu, Nov 6 - Tue, Nov 11
American Airlines Logo
6:11 pm - 12:19 pmGSP-SDQ
17h 08m1 stop
American Airlines Logo
6:00 am - 11:04 amSDQ-GSP
6h 04m1 stop
$487American Airlines
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Sat, Nov 8 - Sat, Nov 15
American Airlines Logo
6:11 pm - 3:45 pmGSP-SDQ
20h 34m1 stop
American Airlines Logo
6:00 am - 6:47 pmSDQ-GSP
13h 47m2 stops
$491American Airlines
Find Deal
Sat, Nov 8 - Sat, Nov 15
Delta Logo
1:32 pm - 1:27 amGSP-SDQ
10h 55m2 stops
Delta Logo
7:01 am - 8:55 pmSDQ-GSP
14h 54m2 stops
$492Delta
Find Deal
Sat, Nov 8 - Sat, Nov 15
United Airlines Logo
6:00 am - 3:06 pmGSP-SDQ
8h 06m1 stop
United Airlines Logo
2:53 pm - 11:56 pmSDQ-GSP
10h 03m1 stop
$612United Airlines
Find Deal
Tue, Nov 11 - Mon, Nov 17
United Airlines Logo
6:00 am - 3:06 pmGSP-SDQ
8h 06m1 stop
United Airlines Logo
4:18 pm - 11:56 pmSDQ-GSP
8h 38m1 stop
$807United Airlines
Find Deal
Tue, Nov 11 - Mon, Nov 17

American Airlines flights from Greenville to Santo Domingo

Our best American Airlines deals on Greenville to Santo Domingo flight tickets
American Airlines
Oct 23
GSP4:46 pmGreenville
20h 49m
1 stop
SDQ1:35 pmSanto Domingo Las Americas
Oct 29
SDQ10:25 amSanto Domingo Las Americas
12h 56m
1 stop
GSP11:21 pmGreenville
$477
Find similar
American Airlines
Oct 23
GSP4:46 pmGreenville
20h 49m
1 stop
SDQ1:35 pmSanto Domingo Las Americas
Oct 29
SDQ10:25 amSanto Domingo Las Americas
9h 59m
2 stops
GSP8:24 pmGreenville
$481
Find similar
American Airlines
Nov 8
GSP6:11 pmGreenville
17h 08m
1 stop
SDQ12:19 pmSanto Domingo Las Americas
Nov 15
SDQ6:00 amSanto Domingo Las Americas
6h 04m
1 stop
GSP11:04 amGreenville
$487
Find similar

Delta flights from Greenville to Santo Domingo

Our best Delta deals on Greenville to Santo Domingo flight tickets
Delta
Nov 5
GSP5:30 amGreenville
8h 11m
1 stop
SDQ2:41 pmSanto Domingo Las Americas
Nov 12
SDQ3:57 pmSanto Domingo Las Americas
6h 28m
1 stop
GSP9:25 pmGreenville
$467
Find similar
Delta
Nov 5
GSP5:30 amGreenville
8h 11m
1 stop
SDQ2:41 pmSanto Domingo Las Americas
Nov 12
SDQ6:45 amSanto Domingo Las Americas
10h 46m
2 stops
GSP4:31 pmGreenville
$472
Find similar
Delta
Nov 6
GSP5:30 amGreenville
12h 54m
2 stops
SDQ7:24 pmSanto Domingo Las Americas
Nov 11
SDQ6:45 amSanto Domingo Las Americas
12h 24m
2 stops
GSP6:09 pmGreenville
$482
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 24, 2025.
Use the filters below to find and compare flights from Greenville to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Wed 11/5

5:30 am-2:41 pm

1 stop8h 11m

Santo Domingo Las Americas

Wed 11/12

3:57 pm-9:25 pm

1 stop6h 28m

$467

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Wed 11/5

5:30 am-2:41 pm

1 stop8h 11m

Santo Domingo Las Americas

Wed 11/12

6:45 am-4:31 pm

2 stops10h 46m

$472

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Thu 10/23

4:46 pm-1:35 pm

1 stop20h 49m

Santo Domingo Las Americas

Wed 10/29

10:25 am-11:21 pm

1 stop12h 56m

$477

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Thu 10/23

4:46 pm-1:35 pm

1 stop20h 49m

Santo Domingo Las Americas

Wed 10/29

10:25 am-8:24 pm

2 stops9h 59m

$481

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Thu 11/6

5:30 am-7:24 pm

2 stops12h 54m

Santo Domingo Las Americas

Tue 11/11

6:45 am-6:09 pm

2 stops12h 24m

$482

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Sat 11/8

6:11 pm-12:19 pm

1 stop17h 08m

Santo Domingo Las Americas

Sat 11/15

6:00 am-11:04 am

1 stop6h 04m

$487

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Sat 11/8

6:11 pm-3:45 pm

1 stop20h 34m

Santo Domingo Las Americas

Sat 11/15

6:00 am-6:47 pm

2 stops13h 47m

$491

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Sat 11/8

1:32 pm-1:27 am

2 stops10h 55m

Santo Domingo Las Americas

Sat 11/15

7:01 am-8:55 pm

2 stops14h 54m

$492

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Tue 11/11

6:00 am-3:06 pm

1 stop8h 06m

Santo Domingo Las Americas

Mon 11/17

2:53 pm-11:56 pm

1 stop10h 03m

$612

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Tue 11/11

6:00 am-3:06 pm

1 stop8h 06m

Santo Domingo Las Americas

Mon 11/17

4:18 pm-11:56 pm

1 stop8h 38m

$807

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Greenville to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in May, then you should wait until January to fly from Greenville, when ticket prices are also cheap, with an average price of $511.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Thursday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $623. The most expensive day to fly to Santo Domingo is Saturday, with ticket prices averaging around $803.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the evening when flights can be purchased for as low as $683. Try not to purchase tickets in the morning because they tend to be around $714. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Greenville to Santo Domingo flights?

You could potentially save up to 1% on your flight if you consider stops on a Greenville to Santo Domingo flight.

When to book flights from Greenville to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Santo Domingo (GSP to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Santo Domingo

Direct flights

None
There are no direct flights from Greenville to Santo Domingo. There are no popular flight routes from Greenville to Santo Domingo.
Search flight deals

  • How far is Greenville to Santo Domingo Las Americas by plane?

    Santo Domingo Las Americas is 1364.2 mi away from Greenville. Flights usually cover this in 5h 30m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Greenville Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Greenville Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Greenville Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents you'll need for your trip to Santo Domingo Las Americas Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santo Domingo Las Americas Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to Santo Domingo?

Best airlines flying from Greenville to Santo Domingo

Compare and see reviews for airlines that fly from Greenville to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $484Free CancellationRating
7.9
7,973 reviews
Search Delta flights
American AirlinesPriceFrom $511Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Santo Domingo?

It is quick and easy to find Greenville to Santo Domingo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santo Domingo that suits you.

Can I find flights from Greenville to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from Greenville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Greenville to Santo Domingo?

momondo helps you find the best flight between Greenville and Santo Domingo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to Santo Domingo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santo Domingo from Greenville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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