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Cheap flights from Greenville to Santiago de los Caballeros from $216

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Santiago de los Caballeros departing on 4/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Greenville to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 12:23 pm
GSP
-
STI
6h 23m
1 stop
American Airlines Logo
1:32 pm - 11:59 pm
STI
-
GSP
10h 27m
1 stop
$519American Airlines
Tue, Apr 21 - Tue, Apr 28
Delta Logo
8:50 am - 12:22 am
GSP
-
STI
15h 32m
2 stops
Delta Logo
6:00 am - 10:46 pm
STI
-
GSP
16h 46m
2 stops
$523Delta
Tue, Apr 21 - Tue, Apr 28
American Airlines Logo
8:00 pm - 9:15 pm
GSP
-
STI
25h 15m
1 stop
American Airlines Logo
3:44 pm - 10:12 am
STI
-
GSP
18h 28m
2 stops
$534American Airlines
Tue, Jul 7 - Tue, Jul 14
Multiple Airlines Logo
6:33 pm - 1:49 am
GSP
-
STI
7h 16m
1 stop
Multiple Airlines Logo
2:46 am - 4:53 pm
STI
-
GSP
14h 07m
1 stop
$539Multiple Airlines
Fri, Apr 3 - Thu, Apr 9
Delta Logo
5:42 am - 7:33 pm
GSP
-
STI
13h 51m
2 stops
Delta Logo
6:00 am - 11:56 pm
STI
-
GSP
17h 56m
2 stops
$543Delta
Tue, Apr 14 - Tue, Apr 21
American Airlines Logo
8:00 pm - 2:44 pm
GSP
-
STI
18h 44m
1 stop
American Airlines Logo
7:03 am - 9:19 pm
STI
-
GSP
14h 16m
2 stops
$544American Airlines
Thu, Jul 16 - Mon, Jul 20
American Airlines Logo
6:45 pm - 12:23 pm
GSP
-
STI
17h 38m
1 stop
American Airlines Logo
1:32 pm - 11:59 pm
STI
-
GSP
10h 27m
1 stop
$550American Airlines
Sat, May 9 - Tue, May 12
American Airlines Logo
12:49 pm - 12:23 pm
GSP
-
STI
23h 34m
2 stops
American Airlines Logo
1:32 pm - 11:59 pm
STI
-
GSP
10h 27m
1 stop
$553American Airlines
Sat, Apr 25 - Sat, May 2
American Airlines Logo
6:00 am - 12:23 pm
GSP
-
STI
6h 23m
1 stop
American Airlines Logo
1:32 pm - 11:59 pm
STI
-
GSP
10h 27m
1 stop
$559American Airlines
Sat, Apr 25 - Sat, May 2
American Airlines Logo
8:00 pm - 9:15 pm
GSP
-
STI
25h 15m
1 stop
American Airlines Logo
9:00 am - 7:30 pm
STI
-
GSP
10h 30m
1 stop
$570American Airlines
Tue, Jul 7 - Tue, Jul 14

American Airlines flights from Greenville to Santiago de los Caballeros

Our best American Airlines deals on Greenville to Santiago de los Caballeros flight tickets
American Airlines
Apr 21
GSP6:00 amGreenville
6h 23m
1 stop
STI12:23 pmSantiago de los Caballeros
Apr 28
STI1:32 pmSantiago de los Caballeros
10h 27m
1 stop
GSP11:59 pmGreenville
$519
American Airlines
Jul 7
GSP8:00 pmGreenville
25h 15m
1 stop
STI9:15 pmSantiago de los Caballeros
Jul 14
STI3:44 pmSantiago de los Caballeros
18h 28m
2 stops
GSP10:12 amGreenville
$534
American Airlines
Jul 16
GSP8:00 pmGreenville
18h 44m
1 stop
STI2:44 pmSantiago de los Caballeros
Jul 20
STI7:03 amSantiago de los Caballeros
14h 16m
2 stops
GSP9:19 pmGreenville
$544

Delta flights from Greenville to Santiago de los Caballeros

Our best Delta deals on Greenville to Santiago de los Caballeros flight tickets
Delta
Apr 21
GSP8:50 amGreenville
15h 32m
2 stops
STI12:22 amSantiago de los Caballeros
Apr 28
STI6:00 amSantiago de los Caballeros
16h 46m
2 stops
GSP10:46 pmGreenville
$523
Delta
Apr 14
GSP5:42 amGreenville
13h 51m
2 stops
STI7:33 pmSantiago de los Caballeros
Apr 21
STI6:00 amSantiago de los Caballeros
17h 56m
2 stops
GSP11:56 pmGreenville
$543

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from Greenville to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

GreenvilleSantiago de los Caballeros

GSP - STI

GSPSTI

Greenville

Tue 4/21

6:00 am-12:23 pm

1 stop6h 23m

Santiago de los Caballeros

Tue 4/28

1:32 pm-11:59 pm

1 stop10h 27m

$519

GreenvilleSantiago de los Caballeros

GSP - STI

GSPSTI

Greenville

Tue 4/21

8:50 am-12:22 am

2 stops15h 32m

Santiago de los Caballeros

Tue 4/28

6:00 am-10:46 pm

2 stops16h 46m

$523

GreenvilleSantiago de los Caballeros

GSP - STI

GSPSTI

Greenville

Tue 7/7

8:00 pm-9:15 pm

1 stop25h 15m

Santiago de los Caballeros

Tue 7/14

3:44 pm-10:12 am

2 stops18h 28m

$534

GreenvilleSantiago de los Caballeros

GSP - STI

GSPSTI

Greenville

Fri 4/3

6:33 pm-1:49 am

1 stop7h 16m

Santiago de los Caballeros

Thu 4/9

2:46 am-4:53 pm

1 stop14h 07m

$539

GreenvilleSantiago de los Caballeros

GSP - STI

GSPSTI

Greenville

Tue 4/14

5:42 am-7:33 pm

2 stops13h 51m

Santiago de los Caballeros

Tue 4/21

6:00 am-11:56 pm

2 stops17h 56m

$543

GreenvilleSantiago de los Caballeros

GSP - STI

GSPSTI

Greenville

Thu 7/16

8:00 pm-2:44 pm

1 stop18h 44m

Santiago de los Caballeros

Mon 7/20

7:03 am-9:19 pm

2 stops14h 16m

$544

GreenvilleSantiago de los Caballeros

GSP - STI

GSPSTI

Greenville

Sat 5/9

6:45 pm-12:23 pm

1 stop17h 38m

Santiago de los Caballeros

Tue 5/12

1:32 pm-11:59 pm

1 stop10h 27m

$550

GreenvilleSantiago de los Caballeros

GSP - STI

GSPSTI

Greenville

Sat 4/25

12:49 pm-12:23 pm

2 stops23h 34m

Santiago de los Caballeros

Sat 5/2

1:32 pm-11:59 pm

1 stop10h 27m

$553

GreenvilleSantiago de los Caballeros

GSP - STI

GSPSTI

Greenville

Sat 4/25

6:00 am-12:23 pm

1 stop6h 23m

Santiago de los Caballeros

Sat 5/2

1:32 pm-11:59 pm

1 stop10h 27m

$559

GreenvilleSantiago de los Caballeros

GSP - STI

GSPSTI

Greenville

Tue 7/7

8:00 pm-9:15 pm

1 stop25h 15m

Santiago de los Caballeros

Tue 7/14

9:00 am-7:30 pm

1 stop10h 30m

$570

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Greenville to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Greenville to Santiago de los Caballeros?

American Airlines is the most popular carrier operating from Greenville to Santiago de los Caballeros

What airlines fly to Santiago de los Caballeros?

American Airlines, Spirit Airlines and Delta are the top three most popular airlines that fly to Santiago de los Caballeros from Greenville according to our data. American Airlines is the first choice among our users, with 69% of people opting to fly with this airline when traveling to Santiago de los Caballeros. Keep in mind that there are 5 different airlines that fly to Santiago de los Caballeros on a routine basis, so you have a few additional options to choose from.

When to book flights from Greenville to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Santiago de los Caballeros (GSP to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Santiago de los Caballeros

Fastest flight time

13h 20m

Direct flights

None
The fastest flight from Greenville to Santiago de los Caballeros takes 13h 20m
There are no direct flights from Greenville to Santiago de los Caballeros. There are no popular flight routes from Greenville to Santiago de los Caballeros.
Search flight deals

  • How far is Greenville to Santiago de los Caballeros by plane?

    A flight from Greenville to Santiago de los Caballeros will travel around 1281.1 mi. In terms of flight time, this usually takes a little over 13h 20m.

  • When did momondo last update prices for flights from Greenville Airport to Santiago de los Caballeros Airport?

    Prices for flights from Greenville Airport to Santiago de los Caballeros Airport are updated daily.

  • How old do you have to be to fly from Greenville Airport to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The required travel and health documents for your Santiago de los Caballeros Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago de los Caballeros Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Santiago de los Caballeros?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Greenville to Santiago de los Caballeros. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Greenville to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Greenville to Santiago de los Caballeros flights to just show those with flexible booking policies.

How can momondo help me find flights from Greenville to Santiago de los Caballeros?

Once you have performed a search for Greenville to Santiago de los Caballeros flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Greenville to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Greenville to Santiago de los Caballeros flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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