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Cheap flights from Greenville to Panama City from $265

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Panama City departing on 5/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Greenville to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:55 am - 2:10 pm
GSP
-
PTY
9h 15m
1 stop
American Airlines Logo
3:35 pm - 11:14 pm
PTY
-
GSP
6h 39m
1 stop
$497American Airlines
Tue, Sep 15 - Thu, Oct 15
American Airlines Logo
7:49 pm - 2:10 pm
GSP
-
PTY
19h 21m
2 stops
American Airlines Logo
3:35 pm - 10:17 am
PTY
-
GSP
17h 42m
2 stops
$501American Airlines
Tue, Sep 15 - Thu, Oct 15
American Airlines Logo
12:55 pm - 2:10 pm
GSP
-
PTY
26h 15m
1 stop
American Airlines Logo
3:40 pm - 11:16 pm
PTY
-
GSP
6h 36m
1 stop
$507American Airlines
Mon, Sep 21 - Tue, Sep 29
United Airlines Logo
7:49 pm - 4:04 am
GSP
-
PTY
9h 15m
1 stop
United Airlines Logo
10:55 pm - 10:37 am
PTY
-
GSP
10h 42m
1 stop
$517United Airlines
Mon, Jul 6 - Mon, Jul 13
United Airlines Logo
8:26 pm - 4:04 am
GSP
-
PTY
8h 38m
1 stop
United Airlines Logo
3:30 pm - 9:43 am
PTY
-
GSP
17h 13m
2 stops
$521United Airlines
Mon, Aug 31 - Wed, Sep 2
American Airlines Logo
6:28 pm - 12:46 pm
GSP
-
PTY
19h 18m
2 stops
American Airlines Logo
1:14 pm - 12:10 pm
PTY
-
GSP
21h 56m
2 stops
$527American Airlines
Thu, May 14 - Thu, May 28
American Airlines Logo
8:20 pm - 12:24 pm
GSP
-
PTY
17h 04m
2 stops
American Airlines Logo
1:24 pm - 11:08 pm
PTY
-
GSP
8h 44m
1 stop
$532American Airlines
Sat, Aug 15 - Wed, Aug 26
American Airlines Logo
6:45 pm - 12:46 pm
GSP
-
PTY
19h 01m
1 stop
American Airlines Logo
1:14 pm - 11:59 pm
PTY
-
GSP
9h 45m
1 stop
$533American Airlines
Thu, May 14 - Thu, May 28
United Airlines Logo
8:26 pm - 4:04 am
GSP
-
PTY
8h 38m
1 stop
United Airlines Logo
10:55 pm - 10:44 am
PTY
-
GSP
10h 49m
1 stop
$536United Airlines
Mon, Aug 31 - Wed, Sep 2
United Airlines Logo
7:00 am - 2:14 pm
GSP
-
PTY
8h 14m
1 stop
United Airlines Logo
10:55 pm - 10:44 am
PTY
-
GSP
10h 49m
1 stop
$538United Airlines
Sat, Aug 15 - Wed, Aug 26

American Airlines flights from Greenville to Panama City

Our best American Airlines deals on Greenville to Panama City flight tickets
American Airlines
Sep 15
GSP5:55 amGreenville
9h 15m
1 stop
PTY2:10 pmPanama City Tocumen Intl
Oct 15
PTY3:35 pmPanama City Tocumen Intl
6h 39m
1 stop
GSP11:14 pmGreenville
$497
American Airlines
Sep 15
GSP5:55 amGreenville
9h 15m
1 stop
PTY2:10 pmPanama City Tocumen Intl
Oct 15
PTY3:35 pmPanama City Tocumen Intl
17h 42m
2 stops
GSP10:17 amGreenville
$501
American Airlines
Sep 21
GSP12:55 pmGreenville
26h 15m
1 stop
PTY2:10 pmPanama City Tocumen Intl
Sep 29
PTY3:40 pmPanama City Tocumen Intl
6h 36m
1 stop
GSP11:16 pmGreenville
$507

United Airlines flights from Greenville to Panama City

Our best United Airlines deals on Greenville to Panama City flight tickets
United Airlines
Jul 6
GSP7:49 pmGreenville
9h 15m
1 stop
PTY4:04 amPanama City Tocumen Intl
Jul 13
PTY10:55 pmPanama City Tocumen Intl
10h 42m
1 stop
GSP10:37 amGreenville
$517
United Airlines
Aug 31
GSP8:26 pmGreenville
8h 38m
1 stop
PTY4:04 amPanama City Tocumen Intl
Sep 2
PTY3:30 pmPanama City Tocumen Intl
17h 13m
2 stops
GSP9:43 amGreenville
$521
United Airlines
Aug 31
GSP8:26 pmGreenville
8h 38m
1 stop
PTY4:04 amPanama City Tocumen Intl
Sep 2
PTY10:55 pmPanama City Tocumen Intl
10h 49m
1 stop
GSP10:44 amGreenville
$536

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 17, 2026.
Use the filters below to find and compare flights from Greenville to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Tue 9/15

5:55 am-2:10 pm

1 stop9h 15m

Panama City Tocumen Intl

Thu 10/15

3:35 pm-11:14 pm

1 stop6h 39m

$497

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Tue 9/15

7:49 pm-2:10 pm

2 stops19h 21m

Panama City Tocumen Intl

Thu 10/15

3:35 pm-10:17 am

2 stops17h 42m

$501

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 9/21

12:55 pm-2:10 pm

1 stop26h 15m

Panama City Tocumen Intl

Tue 9/29

3:40 pm-11:16 pm

1 stop6h 36m

$507

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 7/6

7:49 pm-4:04 am

1 stop9h 15m

Panama City Tocumen Intl

Mon 7/13

10:55 pm-10:37 am

1 stop10h 42m

$517

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 8/31

8:26 pm-4:04 am

1 stop8h 38m

Panama City Tocumen Intl

Wed 9/2

3:30 pm-9:43 am

2 stops17h 13m

$521

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Thu 5/14

6:28 pm-12:46 pm

2 stops19h 18m

Panama City Tocumen Intl

Thu 5/28

1:14 pm-12:10 pm

2 stops21h 56m

$527

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Sat 8/15

8:20 pm-12:24 pm

2 stops17h 04m

Panama City Tocumen Intl

Wed 8/26

1:24 pm-11:08 pm

1 stop8h 44m

$532

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Thu 5/14

6:45 pm-12:46 pm

1 stop19h 01m

Panama City Tocumen Intl

Thu 5/28

1:14 pm-11:59 pm

1 stop9h 45m

$533

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 8/31

8:26 pm-4:04 am

1 stop8h 38m

Panama City Tocumen Intl

Wed 9/2

10:55 pm-10:44 am

1 stop10h 49m

$536

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Sat 8/15

7:00 am-2:14 pm

1 stop8h 14m

Panama City Tocumen Intl

Wed 8/26

10:55 pm-10:44 am

1 stop10h 49m

$538

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Greenville to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Greenville and Panama City?

When to book flights from Greenville to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Panama City (GSP to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Panama City

Fastest flight time

8h 14m

Direct flights

None
The fastest flight from Greenville to Panama City takes 8h 14m
There are no direct flights from Greenville to Panama City. There are no popular flight routes from Greenville to Panama City.
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Frequently asked questions about flying from Greenville to Panama City

  • How far is Greenville to Panama City Tocumen Intl by plane?

    A flight from Greenville to Panama City Tocumen Intl will travel around 1795.3 mi. 8h 14m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Greenville Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Greenville Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Greenville Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Greenville Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Greenville Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to Panama City?

Best airlines flying from Greenville to Panama City

Compare and see reviews for airlines that fly from Greenville to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $371Free CancellationRating
7.9
8,408 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Panama City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Greenville.

Can I find flights from Greenville to Panama City with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Greenville to Panama City flights to just show those with flexible booking policies.

How can momondo help me find flights from Greenville to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Greenville.

I’m not ready to book a flight from Greenville to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Greenville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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