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Cheap flights from Greenville to Panama City from $195

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Panama City departing on 4/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Greenville to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:10 pm - 12:46 pm
GSP
-
PTY
19h 36m
2 stops
American Airlines Logo
1:49 pm - 10:19 am
PTY
-
GSP
19h 30m
2 stops
$447American Airlines
Tue, Apr 14 - Tue, Apr 21
United Airlines Logo
12:07 pm - 7:31 pm
GSP
-
PTY
8h 24m
1 stop
United Airlines Logo
3:30 pm - 9:59 pm
PTY
-
GSP
29h 29m
1 stop
$452United Airlines
Thu, Apr 9 - Mon, Apr 13
American Airlines Logo
6:45 pm - 12:46 pm
GSP
-
PTY
19h 01m
1 stop
American Airlines Logo
1:49 pm - 10:19 am
PTY
-
GSP
19h 30m
2 stops
$456American Airlines
Tue, Apr 14 - Tue, Apr 21
United Airlines Logo
7:00 am - 2:14 pm
GSP
-
PTY
8h 14m
1 stop
United Airlines Logo
3:30 pm - 9:53 pm
PTY
-
GSP
29h 23m
1 stop
$470United Airlines
Wed, Aug 12 - Sun, Aug 16
American Airlines Logo
7:26 pm - 12:41 pm
GSP
-
PTY
18h 15m
1 stop
American Airlines Logo
1:40 pm - 8:38 am
PTY
-
GSP
17h 58m
2 stops
$475American Airlines
Sun, Mar 29 - Thu, Apr 2
United Airlines Logo
7:49 pm - 4:04 am
GSP
-
PTY
9h 15m
1 stop
United Airlines Logo
10:55 pm - 10:44 am
PTY
-
GSP
10h 49m
1 stop
$486United Airlines
Mon, Aug 10 - Wed, Aug 12
United Airlines Logo
4:41 pm - 2:14 pm
GSP
-
PTY
22h 33m
1 stop
United Airlines Logo
7:55 am - 9:59 pm
PTY
-
GSP
13h 04m
1 stop
$488United Airlines
Sat, Apr 11 - Sat, Apr 18
United Airlines Logo
7:49 pm - 4:04 am
GSP
-
PTY
9h 15m
1 stop
United Airlines Logo
3:30 pm - 9:53 pm
PTY
-
GSP
29h 23m
1 stop
$496United Airlines
Mon, Aug 10 - Wed, Aug 12
American Airlines Logo
8:17 pm - 3:01 pm
GSP
-
PTY
19h 44m
2 stops
American Airlines Logo
1:49 pm - 11:44 am
PTY
-
GSP
20h 55m
2 stops
$505American Airlines
Wed, Apr 1 - Wed, Apr 8
American Airlines Logo
7:26 pm - 3:01 pm
GSP
-
PTY
20h 35m
1 stop
American Airlines Logo
1:49 pm - 11:44 am
PTY
-
GSP
20h 55m
2 stops
$514American Airlines
Wed, Apr 1 - Wed, Apr 8

American Airlines flights from Greenville to Panama City

Our best American Airlines deals on Greenville to Panama City flight tickets
American Airlines
Apr 14
GSP6:10 pmGreenville
19h 36m
2 stops
PTY12:46 pmPanama City Tocumen Intl
Apr 21
PTY1:49 pmPanama City Tocumen Intl
19h 30m
2 stops
GSP10:19 amGreenville
$447
American Airlines
Apr 14
GSP6:45 pmGreenville
19h 01m
1 stop
PTY12:46 pmPanama City Tocumen Intl
Apr 21
PTY1:49 pmPanama City Tocumen Intl
19h 30m
2 stops
GSP10:19 amGreenville
$456
American Airlines
Mar 29
GSP7:26 pmGreenville
18h 15m
1 stop
PTY12:41 pmPanama City Tocumen Intl
Apr 2
PTY1:40 pmPanama City Tocumen Intl
17h 58m
2 stops
GSP8:38 amGreenville
$475

United Airlines flights from Greenville to Panama City

Our best United Airlines deals on Greenville to Panama City flight tickets
United Airlines
Apr 9
GSP12:07 pmGreenville
8h 24m
1 stop
PTY7:31 pmPanama City Tocumen Intl
Apr 13
PTY3:30 pmPanama City Tocumen Intl
29h 29m
1 stop
GSP9:59 pmGreenville
$452
United Airlines
Aug 12
GSP7:00 amGreenville
8h 14m
1 stop
PTY2:14 pmPanama City Tocumen Intl
Aug 16
PTY3:30 pmPanama City Tocumen Intl
29h 23m
1 stop
GSP9:53 pmGreenville
$470
United Airlines
Aug 10
GSP7:49 pmGreenville
9h 15m
1 stop
PTY4:04 amPanama City Tocumen Intl
Aug 12
PTY10:55 pmPanama City Tocumen Intl
10h 49m
1 stop
GSP10:44 amGreenville
$486

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 1, 2026.
Use the filters below to find and compare flights from Greenville to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Tue 4/14

6:10 pm-12:46 pm

2 stops19h 36m

Panama City Tocumen Intl

Tue 4/21

1:49 pm-10:19 am

2 stops19h 30m

$447

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Thu 4/9

12:07 pm-7:31 pm

1 stop8h 24m

Panama City Tocumen Intl

Mon 4/13

3:30 pm-9:59 pm

1 stop29h 29m

$452

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Tue 4/14

6:45 pm-12:46 pm

1 stop19h 01m

Panama City Tocumen Intl

Tue 4/21

1:49 pm-10:19 am

2 stops19h 30m

$456

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Wed 8/12

7:00 am-2:14 pm

1 stop8h 14m

Panama City Tocumen Intl

Sun 8/16

3:30 pm-9:53 pm

1 stop29h 23m

$470

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Sun 3/29

7:26 pm-12:41 pm

1 stop18h 15m

Panama City Tocumen Intl

Thu 4/2

1:40 pm-8:38 am

2 stops17h 58m

$475

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 8/10

7:49 pm-4:04 am

1 stop9h 15m

Panama City Tocumen Intl

Wed 8/12

10:55 pm-10:44 am

1 stop10h 49m

$486

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Sat 4/11

4:41 pm-2:14 pm

1 stop22h 33m

Panama City Tocumen Intl

Sat 4/18

7:55 am-9:59 pm

1 stop13h 04m

$488

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 8/10

7:49 pm-4:04 am

1 stop9h 15m

Panama City Tocumen Intl

Wed 8/12

3:30 pm-9:53 pm

1 stop29h 23m

$496

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Wed 4/1

8:17 pm-3:01 pm

2 stops19h 44m

Panama City Tocumen Intl

Wed 4/8

1:49 pm-11:44 am

2 stops20h 55m

$505

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Wed 4/1

7:26 pm-3:01 pm

1 stop20h 35m

Panama City Tocumen Intl

Wed 4/8

1:49 pm-11:44 am

2 stops20h 55m

$514

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Greenville to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, August is the cheapest month to fly from Greenville to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $371. If you’re not able to fly to Panama City in August, then October is your next best option. Flight prices from Greenville to Panama City during October average around $391.

When to book flights from Greenville to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Panama City (GSP to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Panama City

Fastest flight time

8h 14m

Direct flights

None
The fastest flight from Greenville to Panama City takes 8h 14m
There are no direct flights from Greenville to Panama City. There are no popular flight routes from Greenville to Panama City.
Search flight deals

  • How far is Greenville to Panama City Tocumen Intl by plane?

    A flight from Greenville to Panama City Tocumen Intl will travel around 1795.3 mi. 8h 14m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Greenville Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Greenville Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Greenville Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Greenville Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Greenville Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to Panama City?

Best airlines flying from Greenville to Panama City

Compare and see reviews for airlines that fly from Greenville to Panama City with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $353Free CancellationRating
7.1
11,370 reviews
Search American Airlines flights
DeltaPriceFrom $371Free CancellationRating
7.9
8,244 reviews
Search Delta flights
United AirlinesPriceFrom $391Free CancellationRating
7.4
9,370 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Panama City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Greenville.

Can I find flights from Greenville to Panama City with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Greenville to Panama City flights to just show those with flexible booking policies.

How can momondo help me find flights from Greenville to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Greenville.

I’m not ready to book a flight from Greenville to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Greenville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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