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Cheap flights from Greenville to Panama City from $179

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Panama City departing on 3/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Greenville to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:53 pm - 1:40 pm
GSP
-
PTY
18h 47m
2 stops
American Airlines Logo
2:40 pm - 12:14 pm
PTY
-
GSP
21h 34m
2 stops
$417American Airlines
Tue, Feb 24 - Wed, Mar 4
American Airlines Logo
7:26 pm - 12:40 pm
GSP
-
PTY
18h 14m
1 stop
American Airlines Logo
3:10 pm - 10:15 am
PTY
-
GSP
18h 05m
2 stops
$426American Airlines
Mon, Mar 9 - Tue, Mar 17
United Airlines Logo
6:49 am - 5:07 pm
GSP
-
PTY
10h 18m
1 stop
United Airlines Logo
3:41 pm - 9:58 pm
PTY
-
GSP
29h 17m
1 stop
$427United Airlines
Tue, Feb 3 - Tue, Mar 10
American Airlines Logo
8:17 pm - 2:20 pm
GSP
-
PTY
19h 03m
2 stops
American Airlines Logo
1:40 pm - 10:56 am
PTY
-
GSP
20h 16m
2 stops
$435American Airlines
Sun, Mar 8 - Tue, Mar 17
American Airlines Logo
7:26 pm - 12:40 pm
GSP
-
PTY
18h 14m
1 stop
American Airlines Logo
1:40 pm - 12:14 pm
PTY
-
GSP
21h 34m
2 stops
$444American Airlines
Mon, Mar 9 - Mon, Mar 16
Copa Airlines Logo
12:07 pm - 5:10 am
GSP
-
PTY
17h 03m
1 stop
Copa Airlines Logo
3:41 pm - 9:58 pm
PTY
-
GSP
29h 17m
1 stop
$445Copa Airlines
Sat, Mar 7 - Thu, Mar 12
American Airlines Logo
3:58 pm - 12:40 pm
GSP
-
PTY
21h 42m
2 stops
American Airlines Logo
1:40 pm - 12:14 pm
PTY
-
GSP
21h 34m
2 stops
$453American Airlines
Sun, Mar 8 - Mon, Mar 16
American Airlines Logo
7:26 pm - 2:20 pm
GSP
-
PTY
19h 54m
1 stop
American Airlines Logo
1:40 pm - 12:14 pm
PTY
-
GSP
21h 34m
2 stops
$463American Airlines
Sun, Mar 8 - Mon, Mar 16
United Airlines Logo
6:52 am - 4:07 pm
GSP
-
PTY
10h 15m
1 stop
United Airlines Logo
3:41 pm - 9:58 pm
PTY
-
GSP
29h 17m
1 stop
$465United Airlines
Sun, Mar 8 - Tue, Mar 17
United Airlines Logo
4:55 pm - 2:14 pm
GSP
-
PTY
22h 19m
1 stop
United Airlines Logo
3:30 pm - 9:59 pm
PTY
-
GSP
29h 29m
1 stop
$467United Airlines
Sat, Apr 4 - Sun, Apr 12

American Airlines flights from Greenville to Panama City

Our best American Airlines deals on Greenville to Panama City flight tickets
American Airlines
Feb 24
GSP6:53 pmGreenville
18h 47m
2 stops
PTY1:40 pmPanama City Tocumen Intl
Mar 4
PTY2:40 pmPanama City Tocumen Intl
21h 34m
2 stops
GSP12:14 pmGreenville
$417
American Airlines
Mar 9
GSP7:26 pmGreenville
18h 14m
1 stop
PTY12:40 pmPanama City Tocumen Intl
Mar 17
PTY3:10 pmPanama City Tocumen Intl
18h 05m
2 stops
GSP10:15 amGreenville
$426
American Airlines
Mar 8
GSP8:17 pmGreenville
19h 03m
2 stops
PTY2:20 pmPanama City Tocumen Intl
Mar 17
PTY1:40 pmPanama City Tocumen Intl
20h 16m
2 stops
GSP10:56 amGreenville
$435

United Airlines flights from Greenville to Panama City

Our best United Airlines deals on Greenville to Panama City flight tickets
United Airlines
Feb 3
GSP6:49 amGreenville
10h 18m
1 stop
PTY5:07 pmPanama City Tocumen Intl
Mar 10
PTY3:41 pmPanama City Tocumen Intl
29h 17m
1 stop
GSP9:58 pmGreenville
$427
United Airlines
Jan 21
GSP6:49 amGreenville
12h 49m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Jan 27
PTY4:41 pmPanama City Tocumen Intl
22h 54m
1 stop
GSP3:35 pmGreenville
$433
United Airlines
Jan 21
GSP4:50 pmGreenville
26h 48m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Feb 4
PTY9:55 amPanama City Tocumen Intl
12h 02m
1 stop
GSP9:57 pmGreenville
$452

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 16, 2026.
Use the filters below to find and compare flights from Greenville to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Tue 2/24

6:53 pm-1:40 pm

2 stops18h 47m

Panama City Tocumen Intl

Wed 3/4

2:40 pm-12:14 pm

2 stops21h 34m

$417

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 3/9

7:26 pm-12:40 pm

1 stop18h 14m

Panama City Tocumen Intl

Tue 3/17

3:10 pm-10:15 am

2 stops18h 05m

$426

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Tue 2/3

6:49 am-5:07 pm

1 stop10h 18m

Panama City Tocumen Intl

Tue 3/10

3:41 pm-9:58 pm

1 stop29h 17m

$427

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Sun 3/8

8:17 pm-2:20 pm

2 stops19h 03m

Panama City Tocumen Intl

Tue 3/17

1:40 pm-10:56 am

2 stops20h 16m

$435

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 3/9

7:26 pm-12:40 pm

1 stop18h 14m

Panama City Tocumen Intl

Mon 3/16

1:40 pm-12:14 pm

2 stops21h 34m

$444

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Sat 3/7

12:07 pm-5:10 am

1 stop17h 03m

Panama City Tocumen Intl

Thu 3/12

3:41 pm-9:58 pm

1 stop29h 17m

$445

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Sun 3/8

3:58 pm-12:40 pm

2 stops21h 42m

Panama City Tocumen Intl

Mon 3/16

1:40 pm-12:14 pm

2 stops21h 34m

$453

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Sun 3/8

7:26 pm-2:20 pm

1 stop19h 54m

Panama City Tocumen Intl

Mon 3/16

1:40 pm-12:14 pm

2 stops21h 34m

$463

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Sun 3/8

6:52 am-4:07 pm

1 stop10h 15m

Panama City Tocumen Intl

Tue 3/17

3:41 pm-9:58 pm

1 stop29h 17m

$465

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Sat 4/4

4:55 pm-2:14 pm

1 stop22h 19m

Panama City Tocumen Intl

Sun 4/12

3:30 pm-9:59 pm

1 stop29h 29m

$467

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Greenville to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, August is the cheapest month to fly from Greenville to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $371. If you’re not able to fly to Panama City in August, then October is your next best option. Flight prices from Greenville to Panama City during October average around $391.

When to book flights from Greenville to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Panama City (GSP to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Panama City

Fastest flight time

8h 10m

Direct flights

None
The fastest flight from Greenville to Panama City takes 8h 10m
There are no direct flights from Greenville to Panama City. There are no popular flight routes from Greenville to Panama City.
Search flight deals

  • How far is Greenville to Panama City Tocumen Intl by plane?

    A flight from Greenville to Panama City Tocumen Intl will travel around 1795.3 mi. 8h 10m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Greenville Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Greenville Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Greenville Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Greenville Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Greenville Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to Panama City?

Best airlines flying from Greenville to Panama City

Compare and see reviews for airlines that fly from Greenville to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $371Free CancellationRating
7.9
8,051 reviews
Search Delta flights
United AirlinesPriceFrom $383Free CancellationRating
7.4
9,163 reviews
Search United Airlines flights
American AirlinesPriceFrom $383Free CancellationRating
7.2
11,136 reviews
Search American Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Panama City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Greenville.

Can I find flights from Greenville to Panama City with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Greenville to Panama City flights to just show those with flexible booking policies.

How can momondo help me find flights from Greenville to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Greenville.

I’m not ready to book a flight from Greenville to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Greenville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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