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Cheap flights from Detroit to Santa Cruz de la Sierra from $1,427

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Santa Cruz de la Sierra departing on 10/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Detroit to Santa Cruz de la Sierra

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
6:00 am - 2:30 am
DTW
-
VVI
20h 30m
2 stops
Avianca Logo
3:40 am - 3:12 pm
VVI
-
DTW
35h 32m
2 stops
$1,427Avianca
Fri, Oct 23 - Sat, Oct 24
United Airlines Logo
7:00 am - 3:31 am
DTW
-
VVI
44h 31m
2 stops
United Airlines Logo
11:47 am - 8:22 pm
VVI
-
DTW
32h 35m
2 stops
$1,629United Airlines
Thu, Jun 25 - Thu, Jul 2
United Airlines Logo
6:15 am - 10:38 pm
DTW
-
VVI
16h 23m
2 stops
United Airlines Logo
11:47 am - 9:31 am
VVI
-
DTW
21h 44m
2 stops
$3,628United Airlines
Sat, Jun 27 - Sat, Jul 4

United Airlines flights from Detroit to Santa Cruz de la Sierra

Our best United Airlines deals on Detroit to Santa Cruz de la Sierra flight tickets
United Airlines
Jun 25
DTW7:00 amDetroit Metropolitan Wayne County
44h 31m
2 stops
VVI3:31 amSanta Cruz de la Sierra Viru Viru Intl
Jul 2
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
32h 35m
2 stops
DTW8:22 pmDetroit Metropolitan Wayne County
$1,629
United Airlines
Jun 27
DTW6:15 amDetroit Metropolitan Wayne County
16h 23m
2 stops
VVI10:38 pmSanta Cruz de la Sierra Viru Viru Intl
Jul 4
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
21h 44m
2 stops
DTW9:31 amDetroit Metropolitan Wayne County
$3,628

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from Detroit to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Fri 10/23

6:00 am-2:30 am

2 stops20h 30m

Santa Cruz de la Sierra Viru Viru Intl

Sat 10/24

3:40 am-3:12 pm

2 stops35h 32m

$1,427

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Thu 6/25

7:00 am-3:31 am

2 stops44h 31m

Santa Cruz de la Sierra Viru Viru Intl

Thu 7/2

11:47 am-8:22 pm

2 stops32h 35m

$1,629
Quickest round-trip

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Sat 6/27

6:15 am-10:38 pm

2 stops16h 23m

Santa Cruz de la Sierra Viru Viru Intl

Sat 7/4

11:47 am-9:31 am

2 stops21h 44m

$3,628

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Detroit to Santa Cruz de la Sierra

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santa Cruz de la Sierra according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Santa Cruz de la Sierra (DTT to VVI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santa Cruz de la Sierra

Fastest flight time

16h 23m

Direct flights

None
The fastest flight from Detroit to Santa Cruz de la Sierra takes 16h 23m
There are no direct flights from Detroit to Santa Cruz de la Sierra. There are no popular flight routes from Detroit to Santa Cruz de la Sierra.
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Frequently asked questions about flying from Detroit to Santa Cruz de la Sierra

  • How far is Detroit to Santa Cruz de la Sierra Viru Viru Intl by plane?

    Detroit and Santa Cruz de la Sierra Viru Viru Intl are 4342.0 mi apart from one another. A reasonable flight in good conditions will take 16h 23m.

  • When did momondo last update prices for flights from Detroit to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from Detroit to Santa Cruz de la Sierra Viru Viru Intl Airport are updated daily.

  • How old do you have to be to fly from Detroit to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The necessary travel and health documents for your Santa Cruz de la Sierra Viru Viru Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Frequently asked questions about flying from Detroit to Santa Cruz de la Sierra

  • How do I get Price Alerts for flights from Detroit to Santa Cruz de la Sierra?

    You can take advantage of momondo’s Price Alerts by first searching for your flights to Detroit from Santa Cruz de la Sierra. Flight offers will be shown to you in real-time. From there you can create a Price Alert by using our on-site widget.

  • How can I save money on flights from Detroit to Santa Cruz de la Sierra with momondo?

    With “Price Forecast”, learn how soon you should book your flight in advance. Down to the day of week and time of day, our information can inform you on the ideal time to book to save on your travel. Our “Price Calendar” shows you at a quick glance when to book your travel for lower rates. By setting “Price Alerts” you can monitor changes in price and target the ideal time to book. Search for your trip destination by budget amount via our “Explore” feature. Whether you’re looking for ideas for your next travel adventure or cost-cutting tips, our “Discover” content is a great place to start.

  • How does momondo find its flight prices?

    We compare prices from 700+ competitors to help you find the price that works best for you. momondo operates in over 30 international markets, bringing you access to a wide range of fares and deals. Search for your travel using momondo for a diverse range of options from airlines and OTAs.

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santa Cruz de la Sierra?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santa Cruz de la Sierra from Detroit.

Can I find flights from Detroit to Santa Cruz de la Sierra with flexible booking policies on momondo?

Flights from Detroit to Santa Cruz de la Sierra with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Santa Cruz de la Sierra?

Once you have performed a search for Detroit to Santa Cruz de la Sierra flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Detroit to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

Price alerts on flights to Santa Cruz de la Sierra from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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