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Cheap flights from Detroit Metropolitan Wayne County Airport to Santiago from $349

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Santiago departing on 4/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:58 pm - 12:11 am
DTW
-
SCL
28h 13m
2 stops
Multiple Airlines Logo
3:30 pm - 11:59 pm
SCL
-
DTW
32h 29m
3 stops
$820Multiple Airlines
Sun, May 17 - Fri, May 22
Multiple Airlines Logo
6:50 am - 4:45 am
DTW
-
SCL
21h 55m
3 stops
Multiple Airlines Logo
12:30 am - 12:39 am
SCL
-
DTW
24h 09m
3 stops
$841Multiple Airlines
Tue, May 5 - Mon, May 11
Multiple Airlines Logo
6:05 am - 4:17 am
DTW
-
SCL
22h 12m
3 stops
Multiple Airlines Logo
3:30 pm - 11:59 pm
SCL
-
DTW
32h 29m
3 stops
$849Multiple Airlines
Sun, May 17 - Fri, May 22
Multiple Airlines Logo
7:58 pm - 12:11 am
DTW
-
SCL
28h 13m
2 stops
Multiple Airlines Logo
3:20 pm - 11:59 pm
SCL
-
DTW
32h 39m
2 stops
$859Multiple Airlines
Sun, May 17 - Fri, May 22
Multiple Airlines Logo
10:05 am - 3:15 pm
DTW
-
SCL
28h 10m
2 stops
Multiple Airlines Logo
6:40 am - 12:20 pm
SCL
-
DTW
29h 40m
2 stops
$883Multiple Airlines
Fri, Apr 3 - Mon, Apr 6
Multiple Airlines Logo
10:05 am - 5:45 am
DTW
-
SCL
18h 40m
2 stops
Multiple Airlines Logo
3:20 pm - 10:37 pm
SCL
-
DTW
31h 17m
3 stops
$888Multiple Airlines
Fri, Apr 3 - Mon, Apr 6
Multiple Airlines Logo
6:50 am - 4:45 am
DTW
-
SCL
21h 55m
3 stops
Multiple Airlines Logo
3:20 pm - 11:59 pm
SCL
-
DTW
32h 39m
2 stops
$909Multiple Airlines
Sat, May 16 - Tue, May 26
Multiple Airlines Logo
6:50 am - 2:15 pm
DTW
-
SCL
31h 25m
3 stops
Multiple Airlines Logo
3:20 pm - 10:52 pm
SCL
-
DTW
31h 32m
3 stops
$923Multiple Airlines
Sat, May 16 - Tue, May 26
Multiple Airlines Logo
8:15 am - 5:11 am
DTW
-
SCL
19h 56m
2 stops
Multiple Airlines Logo
3:20 pm - 11:59 pm
SCL
-
DTW
32h 39m
2 stops
$936Multiple Airlines
Sat, Apr 4 - Tue, Apr 7
Multiple Airlines Logo
5:45 am - 5:11 am
DTW
-
SCL
22h 26m
2 stops
Multiple Airlines Logo
8:20 pm - 11:59 pm
SCL
-
DTW
27h 39m
3 stops
$939Multiple Airlines
Sat, Apr 4 - Tue, Apr 7

American Airlines flights from Detroit Metropolitan Wayne County Airport to Santiago

Our best American Airlines deals on Detroit Metropolitan Wayne County Airport to Santiago flight tickets
American Airlines
May 5
DTW6:07 amDetroit Metropolitan Wayne County
24h 58m
1 stop
SCL7:05 amSantiago Arturo Merino Benitez
May 12
SCL8:35 pmSantiago Arturo Merino Benitez
19h 56m
2 stops
DTW4:31 pmDetroit Metropolitan Wayne County
$975
American Airlines
May 16
DTW2:11 pmDetroit Metropolitan Wayne County
16h 54m
2 stops
SCL7:05 amSantiago Arturo Merino Benitez
May 26
SCL9:00 pmSantiago Arturo Merino Benitez
18h 28m
2 stops
DTW3:28 pmDetroit Metropolitan Wayne County
$1,013
American Airlines
May 16
DTW5:36 pmDetroit Metropolitan Wayne County
13h 29m
1 stop
SCL7:05 amSantiago Arturo Merino Benitez
May 26
SCL9:00 pmSantiago Arturo Merino Benitez
25h 57m
1 stop
DTW10:57 pmDetroit Metropolitan Wayne County
$1,020

United Airlines flights from Detroit Metropolitan Wayne County Airport to Santiago

Our best United Airlines deals on Detroit Metropolitan Wayne County Airport to Santiago flight tickets
United Airlines
May 5
DTW9:00 amDetroit Metropolitan Wayne County
18h 00m
2 stops
SCL3:00 amSantiago Arturo Merino Benitez
May 12
SCL4:41 amSantiago Arturo Merino Benitez
43h 06m
2 stops
DTW11:47 pmDetroit Metropolitan Wayne County
$961
United Airlines
May 18
DTW9:00 amDetroit Metropolitan Wayne County
20h 10m
2 stops
SCL5:10 amSantiago Arturo Merino Benitez
May 20
SCL12:38 amSantiago Arturo Merino Benitez
21h 46m
2 stops
DTW10:24 pmDetroit Metropolitan Wayne County
$976
United Airlines
Apr 19
DTW9:00 amDetroit Metropolitan Wayne County
37h 43m
2 stops
SCL10:43 pmSantiago Arturo Merino Benitez
Apr 30
SCL4:49 amSantiago Arturo Merino Benitez
42h 58m
2 stops
DTW11:47 pmDetroit Metropolitan Wayne County
$983

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 5/17

7:58 pm-12:11 am

2 stops28h 13m

Santiago Arturo Merino Benitez

Fri 5/22

3:30 pm-11:59 pm

3 stops32h 29m

$820
Quickest round-trip

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Tue 5/5

6:50 am-4:45 am

3 stops21h 55m

Santiago Arturo Merino Benitez

Mon 5/11

12:30 am-12:39 am

3 stops24h 09m

$841

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 5/17

6:05 am-4:17 am

3 stops22h 12m

Santiago Arturo Merino Benitez

Fri 5/22

3:30 pm-11:59 pm

3 stops32h 29m

$849

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 5/17

7:58 pm-12:11 am

2 stops28h 13m

Santiago Arturo Merino Benitez

Fri 5/22

3:20 pm-11:59 pm

2 stops32h 39m

$859

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Fri 4/3

10:05 am-3:15 pm

2 stops28h 10m

Santiago Arturo Merino Benitez

Mon 4/6

6:40 am-12:20 pm

2 stops29h 40m

$883

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Fri 4/3

10:05 am-5:45 am

2 stops18h 40m

Santiago Arturo Merino Benitez

Mon 4/6

3:20 pm-10:37 pm

3 stops31h 17m

$888

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sat 5/16

6:50 am-4:45 am

3 stops21h 55m

Santiago Arturo Merino Benitez

Tue 5/26

3:20 pm-11:59 pm

2 stops32h 39m

$909

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sat 5/16

6:50 am-2:15 pm

3 stops31h 25m

Santiago Arturo Merino Benitez

Tue 5/26

3:20 pm-10:52 pm

3 stops31h 32m

$923

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sat 4/4

8:15 am-5:11 am

2 stops19h 56m

Santiago Arturo Merino Benitez

Tue 4/7

3:20 pm-11:59 pm

2 stops32h 39m

$936

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sat 4/4

5:45 am-5:11 am

2 stops22h 26m

Santiago Arturo Merino Benitez

Tue 4/7

8:20 pm-11:59 pm

3 stops27h 39m

$939

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Detroit Metropolitan Wayne County Airport to Santiago flights?

You could potentially save up to 23% on your flight if you consider stops on a Detroit Metropolitan Wayne County Airport to Santiago flight.

When to book flights from Detroit Metropolitan Wayne County Airport to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Santiago (DTW to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Santiago

Fastest flight time

14h 08m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to Santiago takes 14h 08m
There are no direct flights from Detroit Metropolitan Wayne County Airport to Santiago. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Santiago.
Search flight deals

  • How far is Detroit Metropolitan Wayne County to Santiago Arturo Merino Benitez by plane?

    Santiago Arturo Merino Benitez is 5286.2 mi away from Detroit Metropolitan Wayne County. By plane, this route typically takes 14h 08m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Santiago Arturo Merino Benitez Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to Santiago?

Best airlines flying from Detroit Metropolitan Wayne County Airport to Santiago

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Santiago with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $563Free CancellationRating
7.9
8,318 reviews
Search Delta flights
LATAM AirlinesPriceFrom $733Free CancellationRating
7.4
1,911 reviews
Search LATAM Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

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Why should I use momondo to find a flight deal from Detroit to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Detroit to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Detroit to Santiago with flexible booking policies on momondo?

Flights from Detroit to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Santiago?

Once you have performed a search for Detroit to Santiago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Detroit to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from Detroit. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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