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Cheap flights from Detroit Metropolitan Wayne County Airport to Panama from $173

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Panama departing on 8/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Panama

Cheap round-trip flights

Logo
6:30 am - 9:10 pmDTW-PTY
15h 40m2 stops
Logo
10:05 pm - 8:14 pmPTY-DTW
21h 09m2 stops
$402
Find Deal
Thu, Sep 25 - Sun, Sep 28
Logo
6:35 am - 9:10 pmDTW-PTY
15h 35m2 stops
Logo
10:05 pm - 8:14 pmPTY-DTW
21h 09m2 stops
$421
Find Deal
Wed, Sep 17 - Sun, Sep 21
Logo
6:35 am - 9:10 pmDTW-PTY
15h 35m2 stops
Logo
3:25 am - 8:14 pmPTY-DTW
15h 49m2 stops
$422
Find Deal
Tue, Sep 16 - Mon, Sep 22
Logo
6:30 am - 9:10 pmDTW-PTY
15h 40m2 stops
Logo
10:05 pm - 8:14 pmPTY-DTW
21h 09m2 stops
$432
Find Deal
Mon, Sep 15 - Mon, Sep 22
Logo
6:30 am - 9:10 pmDTW-PTY
15h 40m2 stops
Logo
3:20 am - 8:14 pmPTY-DTW
15h 54m2 stops
$434
Find Deal
Thu, Sep 25 - Sat, Sep 27
Logo
6:30 am - 12:10 amDTW-PTY
18h 40m2 stops
Logo
3:20 am - 8:14 pmPTY-DTW
15h 54m2 stops
$436
Find Deal
Thu, Sep 4 - Wed, Sep 10
Logo
6:35 am - 9:10 pmDTW-PTY
15h 35m2 stops
Logo
3:20 am - 8:14 pmPTY-DTW
15h 54m2 stops
$437
Find Deal
Wed, Sep 17 - Sat, Sep 20
Logo
11:25 am - 12:10 amDTW-PTY
13h 45m2 stops
Logo
10:05 pm - 6:40 pmPTY-DTW
19h 35m2 stops
$439
Find Deal
Tue, Aug 19 - Tue, Aug 26
Logo
6:30 am - 9:10 pmDTW-PTY
15h 40m2 stops
Logo
3:20 am - 8:14 pmPTY-DTW
15h 54m2 stops
$441
Find Deal
Mon, Sep 15 - Sun, Sep 21
Logo
6:30 am - 9:10 pmDTW-PTY
15h 40m2 stops
Logo
10:05 pm - 8:14 pmPTY-DTW
21h 09m2 stops
$443
Find Deal
Thu, Sep 4 - Thu, Sep 11

Delta flights from Detroit Metropolitan Wayne County Airport to Panama

Our best Delta deals on Detroit Metropolitan Wayne County Airport to Panama flight tickets
Delta
Aug 18
DTW5:25 amDetroit Metropolitan Wayne County
8h 25m
1 stop
PTY12:50 pmPanama City Tocumen Intl
Aug 25
PTY2:05 pmPanama City Tocumen Intl
9h 24m
1 stop
DTW12:29 amDetroit Metropolitan Wayne County
$851
Find similar
Delta
Aug 16
DTW5:25 amDetroit Metropolitan Wayne County
8h 25m
1 stop
PTY12:50 pmPanama City Tocumen Intl
Aug 21
PTY2:05 pmPanama City Tocumen Intl
9h 49m
1 stop
DTW12:54 amDetroit Metropolitan Wayne County
$1,113
Find similar

United Airlines flights from Detroit Metropolitan Wayne County Airport to Panama

Our best United Airlines deals on Detroit Metropolitan Wayne County Airport to Panama flight tickets
United Airlines
Aug 12
DTW6:00 amDetroit Metropolitan Wayne County
14h 31m
2 stops
PTY7:31 pmPanama City Tocumen Intl
Aug 20
PTY3:30 pmPanama City Tocumen Intl
23h 37m
1 stop
DTW4:07 pmDetroit Metropolitan Wayne County
$861
Find similar
United Airlines
Aug 18
DTW11:14 amDetroit Metropolitan Wayne County
8h 23m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Aug 25
PTY3:30 pmPanama City Tocumen Intl
20h 44m
2 stops
DTW1:14 pmDetroit Metropolitan Wayne County
$871
Find similar
United Airlines
Aug 8
DTW7:00 amDetroit Metropolitan Wayne County
7h 50m
1 stop
PTY1:50 pmPanama City Tocumen Intl
Aug 16
PTY7:55 amPanama City Tocumen Intl
15h 04m
1 stop
DTW11:59 pmDetroit Metropolitan Wayne County
$1,033
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momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 5, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 9/25

6:30 am-9:10 pm

2 stops15h 40m

Panama City Tocumen Intl

Sun 9/28

10:05 pm-8:14 pm

2 stops21h 09m

$402

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 9/17

6:35 am-9:10 pm

2 stops15h 35m

Panama City Tocumen Intl

Sun 9/21

10:05 pm-8:14 pm

2 stops21h 09m

$421

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 9/16

6:35 am-9:10 pm

2 stops15h 35m

Panama City Tocumen Intl

Mon 9/22

3:25 am-8:14 pm

2 stops15h 49m

$422

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 9/15

6:30 am-9:10 pm

2 stops15h 40m

Panama City Tocumen Intl

Mon 9/22

10:05 pm-8:14 pm

2 stops21h 09m

$432

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 9/25

6:30 am-9:10 pm

2 stops15h 40m

Panama City Tocumen Intl

Sat 9/27

3:20 am-8:14 pm

2 stops15h 54m

$434

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 9/4

6:30 am-12:10 am

2 stops18h 40m

Panama City Tocumen Intl

Wed 9/10

3:20 am-8:14 pm

2 stops15h 54m

$436

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 9/17

6:35 am-9:10 pm

2 stops15h 35m

Panama City Tocumen Intl

Sat 9/20

3:20 am-8:14 pm

2 stops15h 54m

$437

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 8/19

11:25 am-12:10 am

2 stops13h 45m

Panama City Tocumen Intl

Tue 8/26

10:05 pm-6:40 pm

2 stops19h 35m

$439

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 9/15

6:30 am-9:10 pm

2 stops15h 40m

Panama City Tocumen Intl

Sun 9/21

3:20 am-8:14 pm

2 stops15h 54m

$441

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 9/4

6:30 am-9:10 pm

2 stops15h 40m

Panama City Tocumen Intl

Thu 9/11

10:05 pm-8:14 pm

2 stops21h 09m

$443

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of April is, on average, the cheapest month to fly to Panama from Detroit Metropolitan Wayne County Airport, with most prices found around $730. If you don’t want to visit Panama in April, then you should wait until June to fly from Detroit Metropolitan Wayne County Airport, when ticket prices are also cheap, with an average price of $735.

What is the cheapest day to depart on your flight to Panama?

According to our data, Wednesday is the cheapest day to fly to Panama from Detroit Metropolitan Wayne County Airport. The lowest ticket price found for a Wednesday departure recently was $733. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Detroit Metropolitan Wayne County Airport to Panama for around $891.

What is the cheapest time of day to depart on your flight to Panama?

In the evening is the cheapest time of day to fly from Detroit Metropolitan Wayne County Airport to Panama when you can find flight prices for as low as $767. Flying to Panama in the evening is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $794 per ticket.

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Detroit Metropolitan Wayne County Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $860 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Detroit Metropolitan Wayne County Airport for as low as $622 on momondo.

Cheap Detroit Metropolitan Wayne County Airport to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Panama

Best Price Found

$173

Fastest flight time

6h 53m

Direct flights

None

Airports in Panama

1 airport
The best one-way flight to Panama from Detroit Metropolitan Wayne County Airport in the past 72 hours is $173. The best round-trip flight deal from Detroit Metropolitan Wayne County Airport to Panama found on momondo in the last 72 hours is $402.
The fastest flight from Detroit Metropolitan Wayne County Airport to Panama takes 6h 53m
There are no direct flights from Detroit Metropolitan Wayne County Airport to Panama. Popular non-direct route for this connection is Detroit Metropolitan Wayne County Airport - Panama City Tocumen Intl Airport.
There is 1 airport near Panama: Panama City Tocumen Intl (PTY)
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  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Panama?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Panama refresh daily.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Panama?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Panama?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit Metropolitan Wayne County Airport to Panama

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Panama with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $578Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $608Free CancellationRating
7.4
8,916 reviews
Search United Airlines flights
DeltaPriceFrom $608Free CancellationRating
8.0
7,985 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama from Detroit.

Can I find flights from Detroit to Panama with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama from Detroit which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Detroit to Panama?

Once all potential Detroit to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Detroit to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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