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Cheap flights from Detroit Metropolitan Wayne County Airport to Panama from $210

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Panama departing on 4/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
4:50 pm - 2:00 pm
DTW
-
PTY
22h 10m
2 stops
Multiple Airlines Logo
2:55 am - 12:20 pm
PTY
-
DTW
32h 25m
2 stops
$482Multiple Airlines
Tue, Mar 17 - Tue, Mar 24
Multiple Airlines Logo
6:05 am - 2:00 pm
DTW
-
PTY
32h 55m
3 stops
Multiple Airlines Logo
9:45 am - 12:20 pm
PTY
-
DTW
25h 35m
2 stops
$484Multiple Airlines
Tue, Mar 17 - Wed, Mar 25
Multiple Airlines Logo
2:15 pm - 2:00 pm
DTW
-
PTY
24h 45m
2 stops
Multiple Airlines Logo
3:25 am - 10:37 pm
PTY
-
DTW
18h 12m
3 stops
$487Multiple Airlines
Mon, Mar 9 - Tue, Apr 7
Multiple Airlines Logo
7:15 am - 8:19 pm
DTW
-
PTY
14h 04m
1 stop
Multiple Airlines Logo
12:03 pm - 12:46 am
PTY
-
DTW
11h 43m
1 stop
$493Multiple Airlines
Thu, Apr 9 - Thu, Apr 16
Multiple Airlines Logo
5:45 am - 12:40 am
DTW
-
PTY
19h 55m
2 stops
Multiple Airlines Logo
5:55 pm - 12:20 pm
PTY
-
DTW
17h 25m
2 stops
$497Multiple Airlines
Mon, Mar 9 - Wed, Apr 8
Multiple Airlines Logo
2:15 pm - 2:00 pm
DTW
-
PTY
24h 45m
2 stops
Multiple Airlines Logo
3:25 am - 10:37 pm
PTY
-
DTW
18h 12m
3 stops
$502Multiple Airlines
Mon, Mar 9 - Tue, Apr 7
Multiple Airlines Logo
5:20 am - 1:05 am
DTW
-
PTY
20h 45m
2 stops
Multiple Airlines Logo
3:05 am - 11:59 pm
PTY
-
DTW
19h 54m
2 stops
$506Multiple Airlines
Tue, Apr 7 - Mon, Apr 13
Multiple Airlines Logo
5:20 am - 1:05 am
DTW
-
PTY
20h 45m
2 stops
Multiple Airlines Logo
5:30 am - 11:59 pm
PTY
-
DTW
17h 29m
3 stops
$508Multiple Airlines
Tue, Apr 7 - Tue, Apr 14
Multiple Airlines Logo
5:20 am - 4:06 pm
DTW
-
PTY
11h 46m
1 stop
Multiple Airlines Logo
9:33 pm - 12:20 pm
PTY
-
DTW
13h 47m
1 stop
$509Multiple Airlines
Mon, Mar 16 - Mon, Mar 16
Multiple Airlines Logo
6:36 pm - 2:00 pm
DTW
-
PTY
44h 24m
3 stops
Multiple Airlines Logo
3:25 am - 10:37 pm
PTY
-
DTW
18h 12m
3 stops
$510Multiple Airlines
Mon, Mar 9 - Tue, Apr 7

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 23, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 3/17

4:50 pm-2:00 pm

2 stops22h 10m

Panama City Tocumen Intl

Tue 3/24

2:55 am-12:20 pm

2 stops32h 25m

$482

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 3/17

6:05 am-2:00 pm

3 stops32h 55m

Panama City Tocumen Intl

Wed 3/25

9:45 am-12:20 pm

2 stops25h 35m

$484

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 3/9

2:15 pm-2:00 pm

2 stops24h 45m

Panama City Tocumen Intl

Tue 4/7

3:25 am-10:37 pm

3 stops18h 12m

$487

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 4/9

7:15 am-8:19 pm

1 stop14h 04m

Panama City Tocumen Intl

Thu 4/16

12:03 pm-12:46 am

1 stop11h 43m

$493

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 3/9

5:45 am-12:40 am

2 stops19h 55m

Panama City Tocumen Intl

Wed 4/8

5:55 pm-12:20 pm

2 stops17h 25m

$497

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 3/9

2:15 pm-2:00 pm

2 stops24h 45m

Panama City Tocumen Intl

Tue 4/7

3:25 am-10:37 pm

3 stops18h 12m

$502

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 4/7

5:20 am-1:05 am

2 stops20h 45m

Panama City Tocumen Intl

Mon 4/13

3:05 am-11:59 pm

2 stops19h 54m

$506

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 4/7

5:20 am-1:05 am

2 stops20h 45m

Panama City Tocumen Intl

Tue 4/14

5:30 am-11:59 pm

3 stops17h 29m

$508

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 3/16

5:20 am-4:06 pm

1 stop11h 46m

Panama City Tocumen Intl

Mon 3/16

9:33 pm-12:20 pm

1 stop13h 47m

$509

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 3/9

6:36 pm-2:00 pm

3 stops44h 24m

Panama City Tocumen Intl

Tue 4/7

3:25 am-10:37 pm

3 stops18h 12m

$510

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of June is, on average, the cheapest month to fly to Panama from Detroit Metropolitan Wayne County Airport, with most prices found around $722. If you don’t want to visit Panama in June, then you should wait until October to fly from Detroit Metropolitan Wayne County Airport, when ticket prices are also cheap, with an average price of $736.

Cheap Detroit Metropolitan Wayne County Airport to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Panama

Fastest flight time

8h 59m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to Panama takes 8h 59m
There are no direct flights from Detroit Metropolitan Wayne County Airport to Panama. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Panama.
Search flight deals

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Panama?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Panama refresh daily.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Panama?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Panama?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit Metropolitan Wayne County Airport to Panama

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Panama with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $578Free CancellationRating
7.2
11,339 reviews
Search American Airlines flights
DeltaPriceFrom $608Free CancellationRating
7.9
8,234 reviews
Search Delta flights
Copa AirlinesPriceFrom $623Free CancellationRating
7.5
1,555 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $629Free CancellationRating
7.4
9,342 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama from Detroit.

Can I find flights from Detroit to Panama with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama from Detroit which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Detroit to Panama?

Once all potential Detroit to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Detroit to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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