Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Detroit Metropolitan Wayne County Airport to Panama from $260

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Panama departing on 5/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:50 am - 5:00 pm
DTW
-
PTY
35h 10m
3 stops
Multiple Airlines Logo
4:25 am - 7:52 am
PTY
-
DTW
26h 27m
3 stops
$559Multiple Airlines
Mon, Apr 27 - Tue, May 5
Multiple Airlines Logo
6:50 am - 8:37 pm
DTW
-
PTY
14h 47m
2 stops
Multiple Airlines Logo
6:34 pm - 11:59 pm
PTY
-
DTW
28h 25m
1 stop
$562Multiple Airlines
Tue, Jun 2 - Tue, Jun 16
Multiple Airlines Logo
6:50 am - 8:37 pm
DTW
-
PTY
14h 47m
2 stops
Multiple Airlines Logo
12:23 pm - 11:59 pm
PTY
-
DTW
10h 36m
1 stop
$574Multiple Airlines
Tue, Jun 2 - Wed, Jun 17
Multiple Airlines Logo
12:55 pm - 8:06 am
DTW
-
PTY
20h 11m
2 stops
Multiple Airlines Logo
6:34 pm - 11:59 pm
PTY
-
DTW
28h 25m
1 stop
$575Multiple Airlines
Mon, Jun 1 - Tue, Jun 16
Multiple Airlines Logo
2:40 pm - 7:20 pm
DTW
-
PTY
29h 40m
2 stops
Multiple Airlines Logo
6:34 pm - 11:59 pm
PTY
-
DTW
28h 25m
1 stop
$576Multiple Airlines
Sat, May 30 - Tue, Jun 16
Multiple Airlines Logo
8:25 am - 12:35 am
DTW
-
PTY
41h 10m
3 stops
Multiple Airlines Logo
5:30 am - 10:52 pm
PTY
-
DTW
16h 22m
3 stops
$581Multiple Airlines
Mon, Apr 27 - Sat, May 2
Multiple Airlines Logo
12:55 pm - 8:06 am
DTW
-
PTY
20h 11m
2 stops
Multiple Airlines Logo
12:23 pm - 11:59 pm
PTY
-
DTW
10h 36m
1 stop
$587Multiple Airlines
Mon, Jun 1 - Wed, Jun 17
Multiple Airlines Logo
6:20 am - 7:20 pm
DTW
-
PTY
14h 00m
2 stops
Multiple Airlines Logo
12:23 pm - 11:59 pm
PTY
-
DTW
10h 36m
1 stop
$588Multiple Airlines
Wed, Jun 3 - Wed, Jun 17
Multiple Airlines Logo
6:50 am - 12:35 am
DTW
-
PTY
42h 45m
3 stops
Multiple Airlines Logo
3:10 pm - 11:53 pm
PTY
-
DTW
31h 43m
2 stops
$591Multiple Airlines
Mon, Apr 27 - Tue, May 5
Multiple Airlines Logo
8:25 am - 9:15 am
DTW
-
PTY
25h 50m
3 stops
Multiple Airlines Logo
3:10 pm - 11:59 pm
PTY
-
DTW
31h 49m
2 stops
$599Multiple Airlines
Mon, Apr 27 - Sat, May 2

Copa Airlines flights from Detroit Metropolitan Wayne County Airport to Panama

Our best Copa Airlines deals on Detroit Metropolitan Wayne County Airport to Panama flight tickets
Copa Airlines
Apr 16
DTW9:00 amDetroit Metropolitan Wayne County
10h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Apr 29
PTY10:55 pmPanama City Tocumen Intl
15h 53m
1 stop
DTW3:48 pmDetroit Metropolitan Wayne County
$911
Copa Airlines
Apr 20
DTW10:55 amDetroit Metropolitan Wayne County
8h 42m
1 stop
PTY6:37 pmPanama City Tocumen Intl
May 4
PTY3:30 pmPanama City Tocumen Intl
19h 24m
1 stop
DTW11:54 amDetroit Metropolitan Wayne County
$917

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 12, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 4/27

6:50 am-5:00 pm

3 stops35h 10m

Panama City Tocumen Intl

Tue 5/5

4:25 am-7:52 am

3 stops26h 27m

$559

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 6/2

6:50 am-8:37 pm

2 stops14h 47m

Panama City Tocumen Intl

Tue 6/16

6:34 pm-11:59 pm

1 stop28h 25m

$562

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 6/2

6:50 am-8:37 pm

2 stops14h 47m

Panama City Tocumen Intl

Wed 6/17

12:23 pm-11:59 pm

1 stop10h 36m

$574

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 6/1

12:55 pm-8:06 am

2 stops20h 11m

Panama City Tocumen Intl

Tue 6/16

6:34 pm-11:59 pm

1 stop28h 25m

$575

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 5/30

2:40 pm-7:20 pm

2 stops29h 40m

Panama City Tocumen Intl

Tue 6/16

6:34 pm-11:59 pm

1 stop28h 25m

$576

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 4/27

8:25 am-12:35 am

3 stops41h 10m

Panama City Tocumen Intl

Sat 5/2

5:30 am-10:52 pm

3 stops16h 22m

$581

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 6/1

12:55 pm-8:06 am

2 stops20h 11m

Panama City Tocumen Intl

Wed 6/17

12:23 pm-11:59 pm

1 stop10h 36m

$587
Quickest round-trip

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 6/3

6:20 am-7:20 pm

2 stops14h 00m

Panama City Tocumen Intl

Wed 6/17

12:23 pm-11:59 pm

1 stop10h 36m

$588

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 4/27

6:50 am-12:35 am

3 stops42h 45m

Panama City Tocumen Intl

Tue 5/5

3:10 pm-11:53 pm

2 stops31h 43m

$591

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 4/27

8:25 am-9:15 am

3 stops25h 50m

Panama City Tocumen Intl

Sat 5/2

3:10 pm-11:59 pm

2 stops31h 49m

$599

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Panama from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of October is, on average, the cheapest month to fly to Panama from Detroit Metropolitan Wayne County Airport, with most prices found around $704. If you don’t want to visit Panama in October, then you should wait until August to fly from Detroit Metropolitan Wayne County Airport, when ticket prices are also cheap, with an average price of $754.

Cheap Detroit Metropolitan Wayne County Airport to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Panama

Fastest flight time

8h 45m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to Panama takes 8h 45m
There are no direct flights from Detroit Metropolitan Wayne County Airport to Panama. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Panama.
Search flight deals

Frequently asked questions about flying from Detroit Metropolitan Wayne County Airport to Panama

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Panama?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Panama refresh daily.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Panama?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Panama?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit Metropolitan Wayne County Airport to Panama

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Panama with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $611Free CancellationRating
7.5
1,572 reviews
Search Copa Airlines flights
American AirlinesPriceFrom $628Free CancellationRating
7.1
11,570 reviews
Search American Airlines flights
United AirlinesPriceFrom $629Free CancellationRating
7.4
9,574 reviews
Search United Airlines flights
DeltaPriceFrom $668Free CancellationRating
7.9
8,408 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama from Detroit.

Can I find flights from Detroit to Panama with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama from Detroit which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Detroit to Panama?

Once all potential Detroit to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Detroit to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 5/12
Tue 5/19
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo
Flights to Panama Cityfrom $342
Flights to Bocas del Torofrom $790
Flights to Davidfrom $450
Flights to Changuinola