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Cheap flights from Detroit Metropolitan Wayne County Airport to Guayaquil from $391

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Guayaquil departing on 4/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:43 pm - 11:04 pm
DTW
-
GYE
51h 21m
2 stops
Multiple Airlines Logo
11:59 pm - 11:59 pm
GYE
-
DTW
23h 00m
1 stop
$391Multiple Airlines
Thu, Apr 16 - Mon, Apr 27
Spirit Airlines Logo
8:25 am - 11:04 pm
DTW
-
GYE
15h 39m
2 stops
Spirit Airlines Logo
11:59 pm - 9:05 pm
GYE
-
DTW
20h 06m
2 stops
$423Spirit Airlines
Thu, Apr 16 - Mon, Apr 27
Multiple Airlines Logo
4:08 pm - 11:04 pm
DTW
-
GYE
31h 56m
1 stop
Multiple Airlines Logo
11:59 pm - 11:38 am
GYE
-
DTW
34h 39m
2 stops
$442Multiple Airlines
Thu, Apr 16 - Sun, Apr 26
Spirit Airlines Logo
6:10 am - 11:04 pm
DTW
-
GYE
17h 54m
1 stop
Spirit Airlines Logo
11:59 pm - 11:59 pm
GYE
-
DTW
23h 00m
1 stop
$460Spirit Airlines
Thu, Apr 16 - Mon, Apr 27
Spirit Airlines Logo
8:25 am - 11:04 pm
DTW
-
GYE
15h 39m
2 stops
Spirit Airlines Logo
11:59 pm - 10:52 pm
GYE
-
DTW
21h 53m
3 stops
$477Spirit Airlines
Thu, Apr 16 - Mon, Apr 27
Spirit Airlines Logo
8:30 pm - 11:04 pm
DTW
-
GYE
27h 34m
3 stops
Spirit Airlines Logo
11:59 pm - 10:52 pm
GYE
-
DTW
21h 53m
3 stops
$507Spirit Airlines
Thu, Apr 16 - Mon, Apr 27
Spirit Airlines Logo
8:25 am - 11:04 pm
DTW
-
GYE
15h 39m
2 stops
Spirit Airlines Logo
11:59 pm - 9:05 pm
GYE
-
DTW
20h 06m
2 stops
$526Spirit Airlines
Thu, Apr 16 - Sun, Apr 26
Spirit Airlines Logo
6:10 am - 11:04 pm
DTW
-
GYE
17h 54m
1 stop
Spirit Airlines Logo
11:59 pm - 9:05 pm
GYE
-
DTW
20h 06m
2 stops
$538Spirit Airlines
Thu, Apr 16 - Sun, Apr 26
Spirit Airlines Logo
8:25 am - 11:04 pm
DTW
-
GYE
15h 39m
2 stops
Spirit Airlines Logo
11:59 pm - 10:52 pm
GYE
-
DTW
21h 53m
3 stops
$552Spirit Airlines
Thu, Apr 16 - Sun, Apr 26
Multiple Airlines Logo
4:08 pm - 11:04 pm
DTW
-
GYE
31h 56m
1 stop
Multiple Airlines Logo
11:59 pm - 11:59 pm
GYE
-
DTW
23h 00m
1 stop
$562Multiple Airlines
Thu, Apr 16 - Sun, Apr 26

Spirit Airlines flights from Detroit Metropolitan Wayne County Airport to Guayaquil

Our best Spirit Airlines deals on Detroit Metropolitan Wayne County Airport to Guayaquil flight tickets
Spirit Airlines
Apr 16
DTW8:25 amDetroit Metropolitan Wayne County
15h 39m
2 stops
GYE11:04 pmGuayaquil Jose Joaquin de Olmedo
Apr 27
GYE11:59 pmGuayaquil Jose Joaquin de Olmedo
20h 06m
2 stops
DTW9:05 pmDetroit Metropolitan Wayne County
$423
Spirit Airlines
Apr 16
DTW6:10 amDetroit Metropolitan Wayne County
17h 54m
1 stop
GYE11:04 pmGuayaquil Jose Joaquin de Olmedo
Apr 27
GYE11:59 pmGuayaquil Jose Joaquin de Olmedo
23h 00m
1 stop
DTW11:59 pmDetroit Metropolitan Wayne County
$460
Spirit Airlines
Apr 16
DTW8:25 amDetroit Metropolitan Wayne County
15h 39m
2 stops
GYE11:04 pmGuayaquil Jose Joaquin de Olmedo
Apr 27
GYE11:59 pmGuayaquil Jose Joaquin de Olmedo
21h 53m
3 stops
DTW10:52 pmDetroit Metropolitan Wayne County
$477

American Airlines flights from Detroit Metropolitan Wayne County Airport to Guayaquil

Our best American Airlines deals on Detroit Metropolitan Wayne County Airport to Guayaquil flight tickets
American Airlines
May 22
DTW6:04 amDetroit Metropolitan Wayne County
17h 33m
1 stop
GYE10:37 pmGuayaquil Jose Joaquin de Olmedo
Jun 6
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
16h 56m
1 stop
DTW11:56 pmDetroit Metropolitan Wayne County
$665
American Airlines
May 22
DTW10:01 amDetroit Metropolitan Wayne County
13h 36m
2 stops
GYE10:37 pmGuayaquil Jose Joaquin de Olmedo
Jun 6
GYE2:31 pmGuayaquil Jose Joaquin de Olmedo
18h 49m
2 stops
DTW10:20 amDetroit Metropolitan Wayne County
$670
American Airlines
Jun 24
DTW6:57 pmDetroit Metropolitan Wayne County
19h 34m
1 stop
GYE1:31 pmGuayaquil Jose Joaquin de Olmedo
Jul 2
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
16h 56m
1 stop
DTW11:56 pmDetroit Metropolitan Wayne County
$756

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 4/16

8:43 pm-11:04 pm

2 stops51h 21m

Guayaquil Jose Joaquin de Olmedo

Mon 4/27

11:59 pm-11:59 pm

1 stop23h 00m

$391
Quickest round-trip

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 4/16

8:25 am-11:04 pm

2 stops15h 39m

Guayaquil Jose Joaquin de Olmedo

Mon 4/27

11:59 pm-9:05 pm

2 stops20h 06m

$423

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 4/16

4:08 pm-11:04 pm

1 stop31h 56m

Guayaquil Jose Joaquin de Olmedo

Sun 4/26

11:59 pm-11:38 am

2 stops34h 39m

$442

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 4/16

6:10 am-11:04 pm

1 stop17h 54m

Guayaquil Jose Joaquin de Olmedo

Mon 4/27

11:59 pm-11:59 pm

1 stop23h 00m

$460

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 4/16

8:25 am-11:04 pm

2 stops15h 39m

Guayaquil Jose Joaquin de Olmedo

Mon 4/27

11:59 pm-10:52 pm

3 stops21h 53m

$477

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 4/16

8:30 pm-11:04 pm

3 stops27h 34m

Guayaquil Jose Joaquin de Olmedo

Mon 4/27

11:59 pm-10:52 pm

3 stops21h 53m

$507

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 4/16

8:25 am-11:04 pm

2 stops15h 39m

Guayaquil Jose Joaquin de Olmedo

Sun 4/26

11:59 pm-9:05 pm

2 stops20h 06m

$526

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 4/16

6:10 am-11:04 pm

1 stop17h 54m

Guayaquil Jose Joaquin de Olmedo

Sun 4/26

11:59 pm-9:05 pm

2 stops20h 06m

$538

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 4/16

8:25 am-11:04 pm

2 stops15h 39m

Guayaquil Jose Joaquin de Olmedo

Sun 4/26

11:59 pm-10:52 pm

3 stops21h 53m

$552

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 4/16

4:08 pm-11:04 pm

1 stop31h 56m

Guayaquil Jose Joaquin de Olmedo

Sun 4/26

11:59 pm-11:59 pm

1 stop23h 00m

$562

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Guayaquil from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Guayaquil?

The month of February is another great option to travel to Guayaquil, with average flight prices from Detroit Metropolitan Wayne County Airport averaging around $614.

Can stopping save me money on Detroit Metropolitan Wayne County Airport to Guayaquil flights?

You could potentially save up to 46% on your flight if you consider stops on a Detroit Metropolitan Wayne County Airport to Guayaquil flight.

When to book flights from Detroit Metropolitan Wayne County Airport to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Guayaquil (DTW to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Guayaquil

Fastest flight time

18h 59m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to Guayaquil takes 18h 59m
There are no direct flights from Detroit Metropolitan Wayne County Airport to Guayaquil. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Guayaquil.
Search flight deals

  • How far is Detroit Metropolitan Wayne County to Guayaquil Jose Joaquin de Olmedo by plane?

    Detroit Metropolitan Wayne County and Guayaquil Jose Joaquin de Olmedo are 3074.3 mi apart from one another. By plane, this route typically takes 18h 59m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Guayaquil Jose Joaquin de Olmedo Airport are updated daily.

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Detroit Metropolitan Wayne County Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The travel and health documents required for your trip to Guayaquil Jose Joaquin de Olmedo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guayaquil Jose Joaquin de Olmedo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Guayaquil?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Detroit to Guayaquil for you.

Can I find flights from Detroit to Guayaquil with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to Guayaquil flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to Guayaquil?

Once all potential Detroit to Guayaquil flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Guayaquil right now. Can momondo alert me if prices change?

Price alerts on flights to Guayaquil from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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