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Cheap flights from Detroit Metropolitan Wayne County Airport to Guayaquil from $121

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Guayaquil departing on 2/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:54 am - 12:21 am
DTW
-
GYE
13h 27m1 stop
Multiple Airlines Logo
1:26 am - 1:11 pm
GYE
-
DTW
11h 45m1 stop
$229Multiple Airlines
Thu, Jan 22 - Wed, Feb 4
Multiple Airlines Logo
11:00 am - 12:21 am
DTW
-
GYE
13h 21m2 stops
Multiple Airlines Logo
1:26 am - 1:11 pm
GYE
-
DTW
11h 45m1 stop
$253Multiple Airlines
Thu, Jan 15 - Wed, Jan 28
Multiple Airlines Logo
2:36 pm - 12:21 am
DTW
-
GYE
33h 45m2 stops
Multiple Airlines Logo
1:26 am - 1:11 pm
GYE
-
DTW
11h 45m1 stop
$258Multiple Airlines
Thu, Jan 22 - Wed, Feb 4
Spirit Airlines Logo
5:00 am - 12:21 am
DTW
-
GYE
19h 21m2 stops
Spirit Airlines Logo
1:26 am - 11:41 pm
GYE
-
DTW
22h 15m2 stops
$260Spirit Airlines
Thu, Jan 22 - Wed, Feb 4
Multiple Airlines Logo
6:36 pm - 12:21 am
DTW
-
GYE
29h 45m1 stop
Multiple Airlines Logo
1:26 am - 1:11 pm
GYE
-
DTW
11h 45m1 stop
$262Multiple Airlines
Thu, Jan 15 - Wed, Jan 28
Multiple Airlines Logo
10:54 am - 12:21 am
DTW
-
GYE
13h 27m1 stop
Multiple Airlines Logo
1:26 am - 1:30 pm
GYE
-
DTW
12h 04m2 stops
$265Multiple Airlines
Thu, Jan 22 - Fri, Feb 6
Multiple Airlines Logo
10:54 am - 12:21 am
DTW
-
GYE
13h 27m1 stop
Multiple Airlines Logo
1:26 am - 1:06 pm
GYE
-
DTW
35h 40m2 stops
$271Multiple Airlines
Thu, Jan 22 - Thu, Feb 5
Multiple Airlines Logo
10:54 am - 12:21 am
DTW
-
GYE
13h 27m1 stop
Multiple Airlines Logo
1:26 am - 10:44 pm
GYE
-
DTW
21h 18m1 stop
$274Multiple Airlines
Thu, Jan 22 - Thu, Feb 5
Spirit Airlines Logo
10:08 pm - 12:21 am
DTW
-
GYE
26h 13m2 stops
Spirit Airlines Logo
1:26 am - 11:41 pm
GYE
-
DTW
22h 15m2 stops
$278Spirit Airlines
Thu, Jan 15 - Wed, Jan 28
Spirit Airlines Logo
10:08 pm - 12:21 am
DTW
-
GYE
26h 13m2 stops
Spirit Airlines Logo
1:26 am - 11:41 pm
GYE
-
DTW
22h 15m2 stops
$279Spirit Airlines
Thu, Jan 22 - Fri, Feb 6

Spirit Airlines flights from Detroit Metropolitan Wayne County Airport to Guayaquil

Our best Spirit Airlines deals on Detroit Metropolitan Wayne County Airport to Guayaquil flight tickets
Spirit Airlines
Jan 22
DTW5:00 amDetroit Metropolitan Wayne County
19h 21m
2 stops
GYE12:21 amGuayaquil Jose Joaquin de Olmedo
Feb 4
GYE1:26 amGuayaquil Jose Joaquin de Olmedo
22h 15m
2 stops
DTW11:41 pmDetroit Metropolitan Wayne County
$260
Find similar
Spirit Airlines
Jan 15
DTW10:08 pmDetroit Metropolitan Wayne County
26h 13m
2 stops
GYE12:21 amGuayaquil Jose Joaquin de Olmedo
Jan 28
GYE1:26 amGuayaquil Jose Joaquin de Olmedo
22h 15m
2 stops
DTW11:41 pmDetroit Metropolitan Wayne County
$278
Find similar
Spirit Airlines
Jan 22
DTW10:08 pmDetroit Metropolitan Wayne County
26h 13m
2 stops
GYE12:21 amGuayaquil Jose Joaquin de Olmedo
Feb 6
GYE1:26 amGuayaquil Jose Joaquin de Olmedo
22h 15m
2 stops
DTW11:41 pmDetroit Metropolitan Wayne County
$279
Find similar

United Airlines flights from Detroit Metropolitan Wayne County Airport to Guayaquil

Our best United Airlines deals on Detroit Metropolitan Wayne County Airport to Guayaquil flight tickets
United Airlines
Dec 18
DTW6:00 amDetroit Metropolitan Wayne County
14h 43m
2 stops
GYE8:43 pmGuayaquil Jose Joaquin de Olmedo
Dec 23
GYE8:30 amGuayaquil Jose Joaquin de Olmedo
15h 13m
2 stops
DTW11:43 pmDetroit Metropolitan Wayne County
$2,112
Find similar
United Airlines
Dec 18
DTW6:00 amDetroit Metropolitan Wayne County
14h 43m
2 stops
GYE8:43 pmGuayaquil Jose Joaquin de Olmedo
Dec 25
GYE2:35 pmGuayaquil Jose Joaquin de Olmedo
26h 42m
2 stops
DTW5:17 pmDetroit Metropolitan Wayne County
$2,122
Find similar
United Airlines
Dec 18
DTW6:00 amDetroit Metropolitan Wayne County
14h 43m
2 stops
GYE8:43 pmGuayaquil Jose Joaquin de Olmedo
Dec 26
GYE8:30 amGuayaquil Jose Joaquin de Olmedo
15h 13m
2 stops
DTW11:43 pmDetroit Metropolitan Wayne County
$2,137
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 1/22

10:54 am-12:21 am

1 stop13h 27m

Guayaquil Jose Joaquin de Olmedo

Wed 2/4

1:26 am-1:11 pm

1 stop11h 45m

$229

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 1/15

11:00 am-12:21 am

2 stops13h 21m

Guayaquil Jose Joaquin de Olmedo

Wed 1/28

1:26 am-1:11 pm

1 stop11h 45m

$253

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 1/22

2:36 pm-12:21 am

2 stops33h 45m

Guayaquil Jose Joaquin de Olmedo

Wed 2/4

1:26 am-1:11 pm

1 stop11h 45m

$258

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 1/22

5:00 am-12:21 am

2 stops19h 21m

Guayaquil Jose Joaquin de Olmedo

Wed 2/4

1:26 am-11:41 pm

2 stops22h 15m

$260

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 1/15

6:36 pm-12:21 am

1 stop29h 45m

Guayaquil Jose Joaquin de Olmedo

Wed 1/28

1:26 am-1:11 pm

1 stop11h 45m

$262

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 1/22

10:54 am-12:21 am

1 stop13h 27m

Guayaquil Jose Joaquin de Olmedo

Fri 2/6

1:26 am-1:30 pm

2 stops12h 04m

$265

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 1/22

10:54 am-12:21 am

1 stop13h 27m

Guayaquil Jose Joaquin de Olmedo

Thu 2/5

1:26 am-1:06 pm

2 stops35h 40m

$271

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 1/22

10:54 am-12:21 am

1 stop13h 27m

Guayaquil Jose Joaquin de Olmedo

Thu 2/5

1:26 am-10:44 pm

1 stop21h 18m

$274

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 1/15

10:08 pm-12:21 am

2 stops26h 13m

Guayaquil Jose Joaquin de Olmedo

Wed 1/28

1:26 am-11:41 pm

2 stops22h 15m

$278

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 1/22

10:08 pm-12:21 am

2 stops26h 13m

Guayaquil Jose Joaquin de Olmedo

Fri 2/6

1:26 am-11:41 pm

2 stops22h 15m

$279

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Guayaquil from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit Metropolitan Wayne County Airport and Guayaquil?

What is the cheapest month to fly to Guayaquil?

The month of May is another great option to travel to Guayaquil, with average flight prices from Detroit Metropolitan Wayne County Airport averaging around $637.

What is the cheapest day to depart on your flight to Guayaquil?

The cheapest day to depart from Detroit Metropolitan Wayne County Airport to Guayaquil is on a Tuesday. Travelers who choose to depart for Guayaquil on a Tuesday will often find tickets for as low as $239. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Guayaquil on Sunday is $883.

What is the cheapest time of day to depart on your flight to Guayaquil?

The cheapest time of day to fly to Guayaquil is in the evening when flights can be purchased for as low as $441. Flights to Guayaquil are more costly in the afternoon, with an average ticket price of $655. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

Can stopping save me money on Detroit Metropolitan Wayne County Airport to Guayaquil flights?

You could potentially save up to 82% on your flight if you consider stops on a Detroit Metropolitan Wayne County Airport to Guayaquil flight.

When to book flights from Detroit Metropolitan Wayne County Airport to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Guayaquil (DTW to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Guayaquil

Fastest flight time

18h 51m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to Guayaquil takes 18h 51m
There are no direct flights from Detroit Metropolitan Wayne County Airport to Guayaquil. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Guayaquil.
Search flight deals

  • How far is Detroit Metropolitan Wayne County to Guayaquil Jose Joaquin de Olmedo by plane?

    Detroit Metropolitan Wayne County and Guayaquil Jose Joaquin de Olmedo are 3074.3 mi apart from one another. By plane, this route typically takes 18h 51m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Guayaquil Jose Joaquin de Olmedo Airport are updated daily.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Detroit Metropolitan Wayne County Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The travel and health documents required for your trip to Guayaquil Jose Joaquin de Olmedo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guayaquil Jose Joaquin de Olmedo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to Guayaquil?

Best airlines flying from Detroit Metropolitan Wayne County Airport to Guayaquil

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $593Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Guayaquil?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Detroit to Guayaquil for you.

Can I find flights from Detroit to Guayaquil with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to Guayaquil flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to Guayaquil?

Once all potential Detroit to Guayaquil flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Guayaquil right now. Can momondo alert me if prices change?

Price alerts on flights to Guayaquil from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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