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Cheap flights from Detroit Metropolitan Wayne County Airport to Guayaquil from $173

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Guayaquil departing on 9/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
7:00 am - 3:14 pm
DTW
-
GYE
9h 14m
1 stop
JetBlue Logo
12:30 pm - 11:30 pm
GYE
-
DTW
10h 00m
1 stop
$398JetBlue
Mon, Sep 14 - Tue, Sep 22
American Airlines Logo
7:13 pm - 1:33 pm
DTW
-
GYE
19h 20m
2 stops
American Airlines Logo
2:30 pm - 12:28 pm
GYE
-
DTW
20h 58m
2 stops
$407American Airlines
Sat, Oct 17 - Sat, Oct 24
JetBlue Logo
6:00 am - 3:20 pm
DTW
-
GYE
10h 20m
1 stop
JetBlue Logo
12:30 pm - 11:30 pm
GYE
-
DTW
10h 00m
1 stop
$432JetBlue
Wed, Aug 26 - Wed, Sep 9
GOL Logo
7:59 pm - 10:11 pm
DTW
-
GYE
27h 12m
2 stops
GOL Logo
2:30 pm - 10:53 am
GYE
-
DTW
19h 23m
2 stops
$440GOL
Sun, Sep 27 - Mon, Oct 5
JetBlue Logo
3:50 pm - 3:14 pm
DTW
-
GYE
24h 24m
1 stop
JetBlue Logo
12:30 pm - 11:30 pm
GYE
-
DTW
10h 00m
1 stop
$471JetBlue
Sun, Sep 27 - Mon, Oct 5
Multiple Airlines Logo
7:00 am - 3:14 pm
DTW
-
GYE
9h 14m
1 stop
Multiple Airlines Logo
1:21 pm - 9:56 pm
GYE
-
DTW
31h 35m
2 stops
$530Multiple Airlines
Mon, Sep 14 - Tue, Sep 22
American Airlines Logo
7:13 pm - 1:33 pm
DTW
-
GYE
19h 20m
2 stops
American Airlines Logo
8:25 am - 10:41 pm
GYE
-
DTW
13h 16m
1 stop
$553American Airlines
Sat, Oct 17 - Sat, Oct 24
American Airlines Logo
6:00 am - 10:11 pm
DTW
-
GYE
17h 11m
1 stop
American Airlines Logo
2:30 pm - 12:30 pm
GYE
-
DTW
21h 00m
2 stops
$557American Airlines
Sun, Sep 27 - Mon, Oct 5
Multiple Airlines Logo
2:32 pm - 8:09 am
DTW
-
GYE
42h 37m
2 stops
Multiple Airlines Logo
12:30 pm - 11:30 pm
GYE
-
DTW
10h 00m
1 stop
$575Multiple Airlines
Mon, Sep 14 - Tue, Sep 22
Multiple Airlines Logo
5:30 pm - 7:45 am
DTW
-
GYE
15h 15m
1 stop
Multiple Airlines Logo
4:05 pm - 3:50 pm
GYE
-
DTW
22h 45m
1 stop
$600Multiple Airlines
Sat, Oct 17 - Sat, Oct 24

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American Airlines flights from Detroit Metropolitan Wayne County Airport to Guayaquil

Our best American Airlines deals on Detroit Metropolitan Wayne County Airport to Guayaquil flight tickets
American Airlines
Oct 17
DTW7:13 pmDetroit Metropolitan Wayne County
19h 20m
2 stops
GYE1:33 pmGuayaquil Jose Joaquin de Olmedo
Oct 24
GYE2:30 pmGuayaquil Jose Joaquin de Olmedo
20h 58m
2 stops
DTW12:28 pmDetroit Metropolitan Wayne County
$407
American Airlines
Oct 17
DTW7:13 pmDetroit Metropolitan Wayne County
19h 20m
2 stops
GYE1:33 pmGuayaquil Jose Joaquin de Olmedo
Oct 24
GYE8:25 amGuayaquil Jose Joaquin de Olmedo
13h 16m
1 stop
DTW10:41 pmDetroit Metropolitan Wayne County
$553
American Airlines
Sep 27
DTW6:00 amDetroit Metropolitan Wayne County
17h 11m
1 stop
GYE10:11 pmGuayaquil Jose Joaquin de Olmedo
Oct 5
GYE2:30 pmGuayaquil Jose Joaquin de Olmedo
21h 00m
2 stops
DTW12:30 pmDetroit Metropolitan Wayne County
$557

JetBlue flights from Detroit Metropolitan Wayne County Airport to Guayaquil

Our best JetBlue deals on Detroit Metropolitan Wayne County Airport to Guayaquil flight tickets
JetBlue
Sep 14
DTW7:00 amDetroit Metropolitan Wayne County
9h 14m
1 stop
GYE3:14 pmGuayaquil Jose Joaquin de Olmedo
Sep 22
GYE12:30 pmGuayaquil Jose Joaquin de Olmedo
10h 00m
1 stop
DTW11:30 pmDetroit Metropolitan Wayne County
$398
JetBlue
Aug 26
DTW6:00 amDetroit Metropolitan Wayne County
10h 20m
1 stop
GYE3:20 pmGuayaquil Jose Joaquin de Olmedo
Sep 9
GYE12:30 pmGuayaquil Jose Joaquin de Olmedo
10h 00m
1 stop
DTW11:30 pmDetroit Metropolitan Wayne County
$432
JetBlue
Sep 27
DTW3:50 pmDetroit Metropolitan Wayne County
24h 24m
1 stop
GYE3:14 pmGuayaquil Jose Joaquin de Olmedo
Oct 5
GYE12:30 pmGuayaquil Jose Joaquin de Olmedo
10h 00m
1 stop
DTW11:30 pmDetroit Metropolitan Wayne County
$471

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 21, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Mon 9/14

7:00 am-3:14 pm

1 stop9h 14m

Guayaquil Jose Joaquin de Olmedo

Tue 9/22

12:30 pm-11:30 pm

1 stop10h 00m

$398

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Sat 10/17

7:13 pm-1:33 pm

2 stops19h 20m

Guayaquil Jose Joaquin de Olmedo

Sat 10/24

2:30 pm-12:28 pm

2 stops20h 58m

$407

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Wed 8/26

6:00 am-3:20 pm

1 stop10h 20m

Guayaquil Jose Joaquin de Olmedo

Wed 9/9

12:30 pm-11:30 pm

1 stop10h 00m

$432

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Sun 9/27

7:59 pm-10:11 pm

2 stops27h 12m

Guayaquil Jose Joaquin de Olmedo

Mon 10/5

2:30 pm-10:53 am

2 stops19h 23m

$440

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Sun 9/27

3:50 pm-3:14 pm

1 stop24h 24m

Guayaquil Jose Joaquin de Olmedo

Mon 10/5

12:30 pm-11:30 pm

1 stop10h 00m

$471

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Mon 9/14

7:00 am-3:14 pm

1 stop9h 14m

Guayaquil Jose Joaquin de Olmedo

Tue 9/22

1:21 pm-9:56 pm

2 stops31h 35m

$530

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Sat 10/17

7:13 pm-1:33 pm

2 stops19h 20m

Guayaquil Jose Joaquin de Olmedo

Sat 10/24

8:25 am-10:41 pm

1 stop13h 16m

$553

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Sun 9/27

6:00 am-10:11 pm

1 stop17h 11m

Guayaquil Jose Joaquin de Olmedo

Mon 10/5

2:30 pm-12:30 pm

2 stops21h 00m

$557

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Mon 9/14

2:32 pm-8:09 am

2 stops42h 37m

Guayaquil Jose Joaquin de Olmedo

Tue 9/22

12:30 pm-11:30 pm

1 stop10h 00m

$575

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Sat 10/17

5:30 pm-7:45 am

1 stop15h 15m

Guayaquil Jose Joaquin de Olmedo

Sat 10/24

4:05 pm-3:50 pm

1 stop22h 45m

$600

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Guayaquil from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Guayaquil?

The month of January is another great option to travel to Guayaquil, with average flight prices from Detroit Metropolitan Wayne County Airport averaging around $613.

Can stopping save me money on Detroit Metropolitan Wayne County Airport to Guayaquil flights?

You could potentially save up to 55% on your flight if you consider stops on a Detroit Metropolitan Wayne County Airport to Guayaquil flight.

When to book flights from Detroit Metropolitan Wayne County Airport to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Guayaquil (DTW to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Guayaquil

Fastest flight time

9h 14m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to Guayaquil takes 9h 14m
There are no direct flights from Detroit Metropolitan Wayne County Airport to Guayaquil. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Guayaquil.
Search flight deals

Frequently asked questions about flying from Detroit Metropolitan Wayne County Airport to Guayaquil

  • How far is Detroit Metropolitan Wayne County to Guayaquil Jose Joaquin de Olmedo by plane?

    Detroit Metropolitan Wayne County and Guayaquil Jose Joaquin de Olmedo are 3074.3 mi apart from one another. By plane, this route typically takes 9h 14m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Guayaquil Jose Joaquin de Olmedo Airport are updated daily.

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Detroit Metropolitan Wayne County Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The travel and health documents required for your trip to Guayaquil Jose Joaquin de Olmedo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guayaquil Jose Joaquin de Olmedo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Guayaquil?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Detroit to Guayaquil for you.

Can I find flights from Detroit to Guayaquil with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to Guayaquil flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to Guayaquil?

Once all potential Detroit to Guayaquil flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Guayaquil right now. Can momondo alert me if prices change?

Price alerts on flights to Guayaquil from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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