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Cheap flights from Detroit Metropolitan Wayne County Airport to Guayaquil from $184

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Guayaquil departing on 9/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 11:16 pmDTW  Detroit Metropolitan Wayne County-GYE Guayaquil Jose Joaquin de Olmedo
17h 16m2 stops Philadelphia Miami
American Airlines Logo
3:31 pm - 12:58 pmGYE  Guayaquil Jose Joaquin de Olmedo-DTW Detroit Metropolitan Wayne County
21h 27m2 stops Miami Chicago O'Hare Intl
$489American Airlines
Sun, Nov 1 - Mon, Nov 9
American Airlines Logo
7:55 pm - 1:29 pmDTW  Detroit Metropolitan Wayne County-GYE Guayaquil Jose Joaquin de Olmedo
18h 34m2 stops Charlotte Douglas Miami
American Airlines Logo
2:29 pm - 12:40 pmGYE  Guayaquil Jose Joaquin de Olmedo-DTW Detroit Metropolitan Wayne County
21h 11m2 stops Miami Washington, D.C. Reagan-National
$489American Airlines
Sat, Oct 17 - Sat, Oct 24
Multiple Airlines Logo
6:59 pm - 10:45 amDTW  Detroit Metropolitan Wayne County-GYE Guayaquil Jose Joaquin de Olmedo
15h 46m1 stop New York John F Kennedy Intl
Multiple Airlines Logo
3:30 am - 6:08 pmGYE  Guayaquil Jose Joaquin de Olmedo-DTW Detroit Metropolitan Wayne County
14h 38m2 stops Bogotá El Dorado New York John F Kennedy Intl
$532Multiple Airlines
Sun, Nov 1 - Sat, Nov 14
Multiple Airlines Logo
5:30 pm - 10:40 amDTW  Detroit Metropolitan Wayne County-GYE Guayaquil Jose Joaquin de Olmedo
18h 10m1 stop New York John F Kennedy Intl
Multiple Airlines Logo
8:00 pm - 4:32 pmGYE  Guayaquil Jose Joaquin de Olmedo-DTW Detroit Metropolitan Wayne County
19h 32m1 stop New York John F Kennedy Intl
$559Multiple Airlines
Tue, Oct 6 - Tue, Oct 20
American Airlines Logo
6:56 pm - 2:31 pmDTW  Detroit Metropolitan Wayne County-GYE Guayaquil Jose Joaquin de Olmedo
19h 35m1 stop Miami
American Airlines Logo
6:00 am - 6:26 pmGYE  Guayaquil Jose Joaquin de Olmedo-DTW Detroit Metropolitan Wayne County
12h 26m1 stop Miami
$570American Airlines
Thu, Dec 3 - Mon, Dec 7
American Airlines Logo
6:00 am - 11:16 pmDTW  Detroit Metropolitan Wayne County-GYE Guayaquil Jose Joaquin de Olmedo
17h 16m2 stops Philadelphia Miami
American Airlines Logo
6:00 am - 11:54 pmGYE  Guayaquil Jose Joaquin de Olmedo-DTW Detroit Metropolitan Wayne County
17h 54m1 stop Miami
$573American Airlines
Sun, Nov 1 - Mon, Nov 9
American Airlines Logo
6:00 am - 11:16 pmDTW  Detroit Metropolitan Wayne County-GYE Guayaquil Jose Joaquin de Olmedo
17h 16m2 stops Philadelphia Miami
American Airlines Logo
3:31 pm - 9:26 amGYE  Guayaquil Jose Joaquin de Olmedo-DTW Detroit Metropolitan Wayne County
17h 55m2 stops Miami Chicago O'Hare Intl
$573American Airlines
Sun, Nov 1 - Sun, Nov 15
American Airlines Logo
6:56 pm - 2:31 pmDTW  Detroit Metropolitan Wayne County-GYE Guayaquil Jose Joaquin de Olmedo
19h 35m1 stop Miami
American Airlines Logo
6:00 am - 10:59 pmGYE  Guayaquil Jose Joaquin de Olmedo-DTW Detroit Metropolitan Wayne County
16h 59m2 stops Miami New York LaGuardia
$575American Airlines
Thu, Dec 3 - Mon, Dec 7
American Airlines Logo
5:41 pm - 2:31 pmDTW  Detroit Metropolitan Wayne County-GYE Guayaquil Jose Joaquin de Olmedo
20h 50m2 stops Charlotte Douglas Miami
American Airlines Logo
3:31 pm - 12:58 pmGYE  Guayaquil Jose Joaquin de Olmedo-DTW Detroit Metropolitan Wayne County
21h 27m2 stops Miami Chicago O'Hare Intl
$575American Airlines
Sun, Nov 1 - Mon, Nov 9
American Airlines Logo
6:00 am - 10:39 pmDTW  Detroit Metropolitan Wayne County-GYE Guayaquil Jose Joaquin de Olmedo
17h 39m1 stop Miami
American Airlines Logo
2:29 pm - 1:06 pmGYE  Guayaquil Jose Joaquin de Olmedo-DTW Detroit Metropolitan Wayne County
21h 37m2 stops Miami Charlotte Douglas
$575American Airlines
Sat, Oct 17 - Sat, Oct 24

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American Airlines flights from Detroit Metropolitan Wayne County Airport to Guayaquil

Our best American Airlines deals on Detroit Metropolitan Wayne County Airport to Guayaquil flight tickets
American Airlines
Oct 17
DTW7:55 pmDetroit Metropolitan Wayne County
18h 34m
2 stops
GYE1:29 pmGuayaquil Jose Joaquin de Olmedo
Oct 24
GYE2:29 pmGuayaquil Jose Joaquin de Olmedo
21h 11m
2 stops
DTW12:40 pmDetroit Metropolitan Wayne County
$489
American Airlines
Dec 3
DTW6:56 pmDetroit Metropolitan Wayne County
19h 35m
1 stop
GYE2:31 pmGuayaquil Jose Joaquin de Olmedo
Dec 7
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
12h 26m
1 stop
DTW6:26 pmDetroit Metropolitan Wayne County
$570
American Airlines
Nov 1
DTW6:00 amDetroit Metropolitan Wayne County
17h 16m
2 stops
GYE11:16 pmGuayaquil Jose Joaquin de Olmedo
Nov 9
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
17h 54m
1 stop
DTW11:54 pmDetroit Metropolitan Wayne County
$573

LATAM Airlines flights from Detroit Metropolitan Wayne County Airport to Guayaquil

Our best LATAM Airlines deals on Detroit Metropolitan Wayne County Airport to Guayaquil flight tickets
LATAM Airlines
Oct 7
DTW9:10 amDetroit Metropolitan Wayne County
22h 43m
2 stops
GYE6:53 amGuayaquil Jose Joaquin de Olmedo
Oct 20
GYE4:19 pmGuayaquil Jose Joaquin de Olmedo
21h 43m
1 stop
DTW3:02 pmDetroit Metropolitan Wayne County
$665
LATAM Airlines
Oct 7
DTW9:10 amDetroit Metropolitan Wayne County
22h 43m
2 stops
GYE6:53 amGuayaquil Jose Joaquin de Olmedo
Oct 22
GYE6:05 amGuayaquil Jose Joaquin de Olmedo
14h 57m
2 stops
DTW10:02 pmDetroit Metropolitan Wayne County
$707
LATAM Airlines
Oct 6
DTW9:10 amDetroit Metropolitan Wayne County
13h 29m
2 stops
GYE9:39 pmGuayaquil Jose Joaquin de Olmedo
Oct 21
GYE4:19 pmGuayaquil Jose Joaquin de Olmedo
16h 03m
1 stop
DTW9:22 amDetroit Metropolitan Wayne County
$789

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 11, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitGuayaquil

DTW Detroit Metropolitan Wayne County - GYE Guayaquil Jose Joaquin de Olmedo

DTWGYE

Detroit Metropolitan Wayne County

Sun 11/1

6:00 am-11:16 pm

2 stops17h 16m

Guayaquil Jose Joaquin de Olmedo

Mon 11/9

3:31 pm-12:58 pm

2 stops21h 27m

$489

DetroitGuayaquil

DTW Detroit Metropolitan Wayne County - GYE Guayaquil Jose Joaquin de Olmedo

DTWGYE

Detroit Metropolitan Wayne County

Sat 10/17

7:55 pm-1:29 pm

2 stops18h 34m

Guayaquil Jose Joaquin de Olmedo

Sat 10/24

2:29 pm-12:40 pm

2 stops21h 11m

$489
Quickest round-trip

DetroitGuayaquil

DTW Detroit Metropolitan Wayne County - GYE Guayaquil Jose Joaquin de Olmedo

DTWGYE

Detroit Metropolitan Wayne County

Sun 11/1

6:59 pm-10:45 am

1 stop15h 46m

Guayaquil Jose Joaquin de Olmedo

Sat 11/14

3:30 am-6:08 pm

2 stops14h 38m

$532

DetroitGuayaquil

DTW Detroit Metropolitan Wayne County - GYE Guayaquil Jose Joaquin de Olmedo

DTWGYE

Detroit Metropolitan Wayne County

Tue 10/6

5:30 pm-10:40 am

1 stop18h 10m

Guayaquil Jose Joaquin de Olmedo

Tue 10/20

8:00 pm-4:32 pm

1 stop19h 32m

$559

DetroitGuayaquil

DTW Detroit Metropolitan Wayne County - GYE Guayaquil Jose Joaquin de Olmedo

DTWGYE

Detroit Metropolitan Wayne County

Thu 12/3

6:56 pm-2:31 pm

1 stop19h 35m

Guayaquil Jose Joaquin de Olmedo

Mon 12/7

6:00 am-6:26 pm

1 stop12h 26m

$570

DetroitGuayaquil

DTW Detroit Metropolitan Wayne County - GYE Guayaquil Jose Joaquin de Olmedo

DTWGYE

Detroit Metropolitan Wayne County

Sun 11/1

6:00 am-11:16 pm

2 stops17h 16m

Guayaquil Jose Joaquin de Olmedo

Mon 11/9

6:00 am-11:54 pm

1 stop17h 54m

$573

DetroitGuayaquil

DTW Detroit Metropolitan Wayne County - GYE Guayaquil Jose Joaquin de Olmedo

DTWGYE

Detroit Metropolitan Wayne County

Sun 11/1

6:00 am-11:16 pm

2 stops17h 16m

Guayaquil Jose Joaquin de Olmedo

Sun 11/15

3:31 pm-9:26 am

2 stops17h 55m

$573

DetroitGuayaquil

DTW Detroit Metropolitan Wayne County - GYE Guayaquil Jose Joaquin de Olmedo

DTWGYE

Detroit Metropolitan Wayne County

Thu 12/3

6:56 pm-2:31 pm

1 stop19h 35m

Guayaquil Jose Joaquin de Olmedo

Mon 12/7

6:00 am-10:59 pm

2 stops16h 59m

$575

DetroitGuayaquil

DTW Detroit Metropolitan Wayne County - GYE Guayaquil Jose Joaquin de Olmedo

DTWGYE

Detroit Metropolitan Wayne County

Sun 11/1

5:41 pm-2:31 pm

2 stops20h 50m

Guayaquil Jose Joaquin de Olmedo

Mon 11/9

3:31 pm-12:58 pm

2 stops21h 27m

$575

DetroitGuayaquil

DTW Detroit Metropolitan Wayne County - GYE Guayaquil Jose Joaquin de Olmedo

DTWGYE

Detroit Metropolitan Wayne County

Sat 10/17

6:00 am-10:39 pm

1 stop17h 39m

Guayaquil Jose Joaquin de Olmedo

Sat 10/24

2:29 pm-1:06 pm

2 stops21h 37m

$575

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Guayaquil?

The month of March is another great option to travel to Guayaquil, with average flight prices from Detroit Metropolitan Wayne County Airport averaging around $0.

Can stopping save me money on Detroit Metropolitan Wayne County Airport to Guayaquil flights?

You could potentially save up to 23% on your flight if you consider stops on a Detroit Metropolitan Wayne County Airport to Guayaquil flight.

When to book flights from Detroit Metropolitan Wayne County Airport to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Guayaquil (DTW to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Guayaquil

Fastest flight time

12h 56m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to Guayaquil takes 12h 56m
There are no direct flights from Detroit Metropolitan Wayne County Airport to Guayaquil. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Guayaquil.
Search flight deals

Frequently asked questions about flying from Detroit Metropolitan Wayne County Airport to Guayaquil

  • How far is Detroit Metropolitan Wayne County to Guayaquil Jose Joaquin de Olmedo by plane?

    Detroit Metropolitan Wayne County and Guayaquil Jose Joaquin de Olmedo are 3074.3 mi apart from one another. By plane, this route typically takes 12h 56m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Guayaquil Jose Joaquin de Olmedo Airport are updated daily.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Detroit Metropolitan Wayne County Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The travel and health documents required for your trip to Guayaquil Jose Joaquin de Olmedo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guayaquil Jose Joaquin de Olmedo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to Guayaquil?

Best airlines flying from Detroit Metropolitan Wayne County Airport to Guayaquil

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $402Free CancellationRating
7.1
3,034 reviews
Search JetBlue flights

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Why should I use momondo to find a flight deal from Detroit to Guayaquil?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Detroit to Guayaquil for you.

Can I find flights from Detroit to Guayaquil with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to Guayaquil flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to Guayaquil?

Once all potential Detroit to Guayaquil flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Guayaquil right now. Can momondo alert me if prices change?

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