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Cheap flights from Des Moines to Panama City from $630

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Panama City

Cheap round-trip flights

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American Airlines Logo
7:42 pm - 1:02 pmDSM  Des Moines-PTY Panama City Tocumen Intl
17h 20m2 stops Dallas/Fort Worth Miami
American Airlines Logo
2:02 pm - 10:42 amPTY  Panama City Tocumen Intl-DSM Des Moines
20h 40m2 stops Miami Charlotte Douglas
$630American Airlines
Thu, Oct 15 - Thu, Oct 22
American Airlines Logo
6:14 pm - 3:55 pmDSM  Des Moines-PTY Panama City Tocumen Intl
20h 41m2 stops Dallas/Fort Worth Miami
American Airlines Logo
4:55 pm - 1:21 pmPTY  Panama City Tocumen Intl-DSM Des Moines
21h 26m2 stops Miami Chicago O'Hare Intl
$635American Airlines
Fri, Jan 22 - Thu, Jan 28
American Airlines Logo
7:31 pm - 1:02 pmDSM  Des Moines-PTY Panama City Tocumen Intl
17h 31m2 stops Chicago O'Hare Intl Miami
American Airlines Logo
2:02 pm - 12:45 pmPTY  Panama City Tocumen Intl-DSM Des Moines
22h 43m2 stops Miami Philadelphia
$644American Airlines
Thu, Oct 15 - Thu, Oct 22
American Airlines Logo
7:31 pm - 1:02 pmDSM  Des Moines-PTY Panama City Tocumen Intl
17h 31m2 stops Chicago O'Hare Intl Miami
American Airlines Logo
2:02 pm - 12:45 pmPTY  Panama City Tocumen Intl-DSM Des Moines
22h 43m2 stops Miami Philadelphia
$669American Airlines
Fri, Oct 16 - Fri, Oct 23
American Airlines Logo
1:15 pm - 1:02 pmDSM  Des Moines-PTY Panama City Tocumen Intl
23h 47m2 stops Philadelphia Miami
American Airlines Logo
2:02 pm - 10:40 amPTY  Panama City Tocumen Intl-DSM Des Moines
20h 38m2 stops Miami Charlotte Douglas
$703American Airlines
Fri, Oct 16 - Fri, Oct 23
United Airlines Logo
8:00 am - 6:38 pmDSM  Des Moines-PTY Panama City Tocumen Intl
10h 38m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
United Airlines Logo
10:00 am - 10:30 pmPTY  Panama City Tocumen Intl-DSM Des Moines
12h 30m1 stop Houston George Bush Intcntl
$713United Airlines
Wed, Oct 28 - Thu, Apr 1
United Airlines Logo
6:05 am - 7:02 pmDSM  Des Moines-PTY Panama City Tocumen Intl
12h 57m2 stops Chicago O'Hare Intl Newark
United Airlines Logo
10:55 pm - 2:11 pmPTY  Panama City Tocumen Intl-DSM Des Moines
15h 16m2 stops Newark Chicago O'Hare Intl
$717United Airlines
Wed, Oct 28 - Thu, Apr 1
American Airlines Logo
9:45 am - 2:13 pmDSM  Des Moines-PTY Panama City Tocumen Intl
27h 28m2 stops Dallas/Fort Worth Miami
American Airlines Logo
1:44 pm - 11:56 pmPTY  Panama City Tocumen Intl-DSM Des Moines
10h 12m1 stop Miami
$717American Airlines
Mon, Nov 2 - Thu, Apr 1
American Airlines Logo
1:58 pm - 2:13 pmDSM  Des Moines-PTY Panama City Tocumen Intl
23h 15m2 stops Chicago O'Hare Intl Miami
American Airlines Logo
1:44 pm - 8:54 amPTY  Panama City Tocumen Intl-DSM Des Moines
19h 10m2 stops Miami Chicago O'Hare Intl
$717American Airlines
Mon, Nov 2 - Thu, Apr 1
United Airlines Logo
6:45 pm - 7:38 pmDSM  Des Moines-PTY Panama City Tocumen Intl
23h 53m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
United Airlines Logo
7:55 am - 10:30 pmPTY  Panama City Tocumen Intl-DSM Des Moines
14h 35m1 stop Houston George Bush Intcntl
$717United Airlines
Mon, Nov 2 - Thu, Apr 1

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United Airlines flights from Des Moines to Panama City

Our best United Airlines deals on Des Moines to Panama City flight tickets
United Airlines
Oct 28
DSM8:00 amDes Moines
10h 38m
2 stops
PTY6:38 pmPanama City Tocumen Intl
Apr 1
PTY10:00 amPanama City Tocumen Intl
12h 30m
1 stop
DSM10:30 pmDes Moines
$713
United Airlines
Nov 2
DSM6:45 pmDes Moines
23h 53m
2 stops
PTY7:38 pmPanama City Tocumen Intl
Apr 1
PTY7:55 amPanama City Tocumen Intl
14h 35m
1 stop
DSM10:30 pmDes Moines
$717
United Airlines
Oct 13
DSM6:00 amDes Moines
12h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Oct 20
PTY10:00 amPanama City Tocumen Intl
12h 15m
1 stop
DSM10:15 pmDes Moines
$733

Delta flights from Des Moines to Panama City

Our best Delta deals on Des Moines to Panama City flight tickets
Delta
Sep 29
DSM5:45 amDes Moines
7h 13m
1 stop
PTY12:58 pmPanama City Tocumen Intl
Oct 6
PTY2:24 pmPanama City Tocumen Intl
8h 09m
1 stop
DSM10:33 pmDes Moines
$753
Delta
Sep 16
DSM5:45 amDes Moines
7h 13m
1 stop
PTY12:58 pmPanama City Tocumen Intl
Sep 19
PTY2:23 pmPanama City Tocumen Intl
8h 03m
1 stop
DSM10:26 pmDes Moines
$808
Delta
Oct 16
DSM5:35 amDes Moines
7h 24m
1 stop
PTY12:59 pmPanama City Tocumen Intl
Oct 23
PTY2:24 pmPanama City Tocumen Intl
8h 09m
1 stop
DSM10:33 pmDes Moines
$813

momondo Fare Finder

 
Use the filters below to find and compare flights from Des Moines to Panama City that are best for you.

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Price

Cheapest round-trip

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Thu 10/15

7:42 pm-1:02 pm

2 stops17h 20m

Panama City Tocumen Intl

Thu 10/22

2:02 pm-10:42 am

2 stops20h 40m

$630

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Fri 1/22

6:14 pm-3:55 pm

2 stops20h 41m

Panama City Tocumen Intl

Thu 1/28

4:55 pm-1:21 pm

2 stops21h 26m

$635

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Thu 10/15

7:31 pm-1:02 pm

2 stops17h 31m

Panama City Tocumen Intl

Thu 10/22

2:02 pm-12:45 pm

2 stops22h 43m

$644

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Fri 10/16

7:31 pm-1:02 pm

2 stops17h 31m

Panama City Tocumen Intl

Fri 10/23

2:02 pm-12:45 pm

2 stops22h 43m

$669

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Fri 10/16

1:15 pm-1:02 pm

2 stops23h 47m

Panama City Tocumen Intl

Fri 10/23

2:02 pm-10:40 am

2 stops20h 38m

$703
Quickest round-trip

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Wed 10/28

8:00 am-6:38 pm

2 stops10h 38m

Panama City Tocumen Intl

Thu 4/1

10:00 am-10:30 pm

1 stop12h 30m

$713

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Wed 10/28

6:05 am-7:02 pm

2 stops12h 57m

Panama City Tocumen Intl

Thu 4/1

10:55 pm-2:11 pm

2 stops15h 16m

$717

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Mon 11/2

9:45 am-2:13 pm

2 stops27h 28m

Panama City Tocumen Intl

Thu 4/1

1:44 pm-11:56 pm

1 stop10h 12m

$717

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Mon 11/2

1:58 pm-2:13 pm

2 stops23h 15m

Panama City Tocumen Intl

Thu 4/1

1:44 pm-8:54 am

2 stops19h 10m

$717

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Mon 11/2

6:45 pm-7:38 pm

2 stops23h 53m

Panama City Tocumen Intl

Thu 4/1

7:55 am-10:30 pm

1 stop14h 35m

$717

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama City from

How to get the cheapest flight ticket from Des Moines to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, August is the cheapest month to fly from Des Moines to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you’re not able to fly to Panama City in August, then May is your next best option. Flight prices from Des Moines to Panama City during May average around $461.

When to book flights from Des Moines to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Panama City (DSM to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Panama City

Best Price Found

$630

Fastest flight time

10h 38m

Direct flights

None
The best flight deal from Des Moines to Panama City found on momondo in the last 72 hours is $630
The fastest flight from Des Moines to Panama City takes 10h 38m
There are no direct flights from Des Moines to Panama City. There are no popular flight routes from Des Moines to Panama City.
Search flight deals

Frequently asked questions about flying from Des Moines to Panama City

  • How far is Des Moines to Panama City Tocumen Intl by plane?

    The distance between Des Moines and Panama City Tocumen Intl is about 2409.5 mi. Flights usually cover this in 10h 38m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Des Moines Airport to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Des Moines Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Des Moines to Panama City?

Best airlines flying from Des Moines to Panama City

Compare and see reviews for airlines that fly from Des Moines to Panama City with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $461Free CancellationRating
7.4
10,157 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Des Moines to Panama City for you.

Can I find flights from Des Moines to Panama City with flexible booking policies on momondo?

Flights from Des Moines to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Panama City?

momondo helps you find the best flight between Des Moines and Panama City by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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