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Cheap flights from Des Moines to Frankfurt am Main from $450

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Frankfurt am Main departing on 11/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Frankfurt am Main

Cheap round-trip flights

Virgin Atlantic Logo
5:47 am - 8:40 amDSM-FRA
19h 53m1 stop
Virgin Atlantic Logo
9:50 am - 5:46 pmFRA-DSM
14h 56m1 stop
$634Virgin Atlantic
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Fri, Nov 7 - Fri, Nov 14
Scandinavian Airlines Logo
2:13 pm - 2:40 pmDSM-FRA
17h 27m2 stops
Scandinavian Airlines Logo
3:15 pm - 10:30 pmFRA-DSM
37h 15m2 stops
$660Scandinavian Airlines
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Thu, Oct 23 - Mon, Oct 27
KLM Logo
10:21 am - 7:50 amDSM-FRA
14h 29m1 stop
KLM Logo
10:40 am - 8:46 pmFRA-DSM
17h 06m1 stop
$677KLM
Find Deal
Wed, Nov 26 - Fri, Dec 12
KLM Logo
10:21 am - 7:50 amDSM-FRA
14h 29m1 stop
KLM Logo
10:40 am - 8:46 pmFRA-DSM
17h 06m1 stop
$678KLM
Find Deal
Wed, Nov 26 - Fri, Dec 12
American Airlines Logo
6:59 pm - 7:40 pmDSM-FRA
17h 41m2 stops
American Airlines Logo
10:15 am - 10:59 pmFRA-DSM
19h 44m1 stop
$681American Airlines
Find Deal
Tue, Dec 2 - Wed, Dec 17
Multiple Airlines Logo
6:33 pm - 4:45 pmDSM-FRA
15h 12m2 stops
Multiple Airlines Logo
9:50 am - 10:33 pmFRA-DSM
19h 43m1 stop
$682Multiple Airlines
Find Deal
Tue, Dec 2 - Wed, Dec 17
Multiple Airlines Logo
10:21 am - 7:50 amDSM-FRA
14h 29m1 stop
Multiple Airlines Logo
7:05 am - 4:16 pmFRA-DSM
16h 11m2 stops
$683Multiple Airlines
Find Deal
Wed, Nov 26 - Fri, Dec 12
American Airlines Logo
2:15 pm - 8:50 amDSM-FRA
11h 35m1 stop
American Airlines Logo
6:30 am - 5:57 pmFRA-DSM
18h 27m2 stops
$684American Airlines
Find Deal
Wed, Nov 26 - Fri, Dec 12
Delta Logo
6:33 pm - 4:45 pmDSM-FRA
15h 12m2 stops
Delta Logo
9:50 am - 8:46 pmFRA-DSM
17h 56m2 stops
$687Delta
Find Deal
Wed, Nov 26 - Fri, Dec 12
Delta Logo
6:33 pm - 4:45 pmDSM-FRA
15h 12m2 stops
Delta Logo
9:50 am - 9:40 amFRA-DSM
30h 50m2 stops
$711Delta
Find Deal
Wed, Nov 26 - Fri, Dec 12

Delta flights from Des Moines to Frankfurt am Main Airport

Our best Delta deals on Des Moines to Frankfurt am Main Airport flight tickets
Delta
Nov 26
DSM6:33 pmDes Moines
15h 12m
2 stops
FRA4:45 pmFrankfurt am Main
Dec 12
FRA9:50 amFrankfurt am Main
17h 56m
2 stops
DSM8:46 pmDes Moines
$687
Find similar
Delta
Nov 26
DSM6:33 pmDes Moines
15h 12m
2 stops
FRA4:45 pmFrankfurt am Main
Dec 12
FRA9:50 amFrankfurt am Main
30h 50m
2 stops
DSM9:40 amDes Moines
$711
Find similar
Delta
Nov 8
DSM5:47 amDes Moines
19h 53m
1 stop
FRA8:40 amFrankfurt am Main
Nov 16
FRA9:50 amFrankfurt am Main
19h 43m
1 stop
DSM10:33 pmDes Moines
$777
Find similar

KLM flights from Des Moines to Frankfurt am Main Airport

Our best KLM deals on Des Moines to Frankfurt am Main Airport flight tickets
KLM
Nov 26
DSM10:21 amDes Moines
14h 29m
1 stop
FRA7:50 amFrankfurt am Main
Dec 12
FRA10:40 amFrankfurt am Main
17h 06m
1 stop
DSM8:46 pmDes Moines
$677
Find similar
KLM
Nov 26
DSM10:21 amDes Moines
14h 29m
1 stop
FRA7:50 amFrankfurt am Main
Dec 12
FRA10:40 amFrankfurt am Main
17h 06m
1 stop
DSM8:46 pmDes Moines
$678
Find similar
KLM
Nov 2
DSM5:47 amDes Moines
19h 53m
1 stop
FRA8:40 amFrankfurt am Main
Nov 9
FRA9:50 amFrankfurt am Main
14h 56m
1 stop
DSM5:46 pmDes Moines
$721
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Frankfurt am Main Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 18, 2025.
Use the filters below to find and compare flights from Des Moines to Frankfurt am Main Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesFrankfurt am Main

DSM - FRA

DSMFRA

Des Moines

Fri 11/7

5:47 am-8:40 am

1 stop19h 53m

Frankfurt am Main

Fri 11/14

9:50 am-5:46 pm

1 stop14h 56m

$634

Des MoinesFrankfurt am Main

DSM - FRA

DSMFRA

Des Moines

Thu 10/23

2:13 pm-2:40 pm

2 stops17h 27m

Frankfurt am Main

Mon 10/27

3:15 pm-10:30 pm

2 stops37h 15m

$660

Des MoinesFrankfurt am Main

DSM - FRA

DSMFRA

Des Moines

Wed 11/26

10:21 am-7:50 am

1 stop14h 29m

Frankfurt am Main

Fri 12/12

10:40 am-8:46 pm

1 stop17h 06m

$677

Des MoinesFrankfurt am Main

DSM - FRA

DSMFRA

Des Moines

Wed 11/26

10:21 am-7:50 am

1 stop14h 29m

Frankfurt am Main

Fri 12/12

10:40 am-8:46 pm

1 stop17h 06m

$678

Des MoinesFrankfurt am Main

DSM - FRA

DSMFRA

Des Moines

Tue 12/2

6:59 pm-7:40 pm

2 stops17h 41m

Frankfurt am Main

Wed 12/17

10:15 am-10:59 pm

1 stop19h 44m

$681

Des MoinesFrankfurt am Main

DSM - FRA

DSMFRA

Des Moines

Tue 12/2

6:33 pm-4:45 pm

2 stops15h 12m

Frankfurt am Main

Wed 12/17

9:50 am-10:33 pm

1 stop19h 43m

$682

Des MoinesFrankfurt am Main

DSM - FRA

DSMFRA

Des Moines

Wed 11/26

10:21 am-7:50 am

1 stop14h 29m

Frankfurt am Main

Fri 12/12

7:05 am-4:16 pm

2 stops16h 11m

$683

Des MoinesFrankfurt am Main

DSM - FRA

DSMFRA

Des Moines

Wed 11/26

2:15 pm-8:50 am

1 stop11h 35m

Frankfurt am Main

Fri 12/12

6:30 am-5:57 pm

2 stops18h 27m

$684

Des MoinesFrankfurt am Main

DSM - FRA

DSMFRA

Des Moines

Wed 11/26

6:33 pm-4:45 pm

2 stops15h 12m

Frankfurt am Main

Fri 12/12

9:50 am-8:46 pm

2 stops17h 56m

$687

Des MoinesFrankfurt am Main

DSM - FRA

DSMFRA

Des Moines

Wed 11/26

6:33 pm-4:45 pm

2 stops15h 12m

Frankfurt am Main

Fri 12/12

9:50 am-9:40 am

2 stops30h 50m

$711

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Frankfurt am Main from

How to get the cheapest flight ticket from Des Moines to Frankfurt am Main Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Frankfurt am Main Airport?

On average, the least expensive day to fly to Frankfurt am Main Airport from Des Moines is on a Tuesday. momondo users have found tickets for Tuesday departures for as low as $879. However, this price may fluctuate depending on the airline, the season, and holidays. Flights from Des Moines to Frankfurt am Main Airport on a Wednesday will generally be more expensive and average around $1,162. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Frankfurt am Main Airport?

According to our data, the cheapest time of day to fly to Frankfurt am Main Airport is in the afternoon. momondo users have found flights departing from Des Moines to Frankfurt am Main Airport in the afternoon for as low as $1,086. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In contrast, the most expensive time of day to depart to Frankfurt am Main Airport is in the morning when prices are around $1,149.

Can stopping save me money on Des Moines to Frankfurt am Main Airport flights?

You could potentially save up to 15% on your flight if you consider stops on a Des Moines to Frankfurt am Main Airport flight.

When to book flights from Des Moines to Frankfurt am Main Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Frankfurt am Main Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Frankfurt am Main Airport (DSM to FRA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Frankfurt am Main Airport

Direct flights

None
There are no direct flights from Des Moines to Frankfurt am Main Airport. There are no popular flight routes from Des Moines to Frankfurt am Main Airport.
Search flight deals

  • How far is Des Moines to Frankfurt am Main by plane?

    A flight from Des Moines to Frankfurt am Main will travel around 4554.2 mi. By plane, this route typically takes 11h 35m.

  • When did momondo last update prices for flights from Des Moines Airport to Frankfurt am Main Airport?

    Prices for flights from Des Moines Airport to Frankfurt am Main Airport refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to Frankfurt am Main Airport?

  • How old do you have to be to fly from Des Moines Airport to Frankfurt am Main Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Frankfurt am Main Airport.

  • What documentation or ID do you need to fly to Frankfurt am Main Airport?

    The travel and health documents required for your trip to Frankfurt am Main Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Frankfurt am Main Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Des Moines to Frankfurt am Main Airport?

Best airlines flying from Des Moines to Frankfurt am Main Airport

Compare and see reviews for airlines that fly from Des Moines to Frankfurt am Main Airport with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $651Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights
KLMPriceFrom $891Free CancellationRating
7.8
1,386 reviews
Search KLM flights

Traveling to a place near Frankfurt am Main?

Book flights to Frankfurt am Main if you plan to visit one of these locations
Heidelberg
Baden-Baden
Wiesbaden
Mainz
Koblenz
Trier
Rothenburg ob der Tauber
Wurzburg
Fulda
Darmstadt
Kaiserslautern
Heilbronn
Marburg
Cochem
Rüdesheim am Rhein
Bad Homburg
Bernkastel-Kues
Bad Kissingen
Nuerburg
Schwäbisch Hall

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Frankfurt am Main?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Frankfurt am Main from Des Moines.

Can I find flights from Des Moines to Frankfurt am Main with flexible booking policies on momondo?

Yes. All flights to Frankfurt am Main from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to Frankfurt am Main?

Once all potential Des Moines to Frankfurt am Main flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Frankfurt am Main right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Frankfurt am Main, momondo offers a useful price alert feature which will track prices for flights to Frankfurt am Main from Des Moines and alert you when they change.

An easier way to manage your Frankfurt am Main Airport trip

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