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Cheap flights from Charlotte to Santiago from $243

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charlotte to Santiago departing on 12/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Charlotte to Santiago

Cheap round-trip flights

Logo
6:40 am - 5:30 amCLT-SCL
21h 50m2 stops
Logo
4:25 pm - 1:23 pmSCL-CLT
21h 58m2 stops
$582
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Mon, Oct 27 - Sat, Nov 1
Logo
6:00 am - 4:15 amCLT-SCL
22h 15m2 stops
Logo
2:30 pm - 12:23 pmSCL-CLT
21h 53m2 stops
$587
Find Deal
Mon, Sep 1 - Sat, Sep 6
Logo
1:28 pm - 12:15 pmCLT-SCL
21h 47m3 stops
Logo
9:10 pm - 1:23 pmSCL-CLT
17h 13m2 stops
$590
Find Deal
Mon, Oct 27 - Sat, Nov 1
Logo
1:43 pm - 11:20 amCLT-SCL
21h 37m3 stops
Logo
12:35 am - 12:23 pmSCL-CLT
35h 48m3 stops
$595
Find Deal
Mon, Sep 1 - Fri, Sep 5
Logo
1:43 pm - 1:45 pmCLT-SCL
24h 02m2 stops
Logo
9:15 pm - 12:23 pmSCL-CLT
16h 08m2 stops
$596
Find Deal
Mon, Sep 1 - Sun, Sep 7
LATAM Airlines Logo
1:09 pm - 6:50 amCLT-SCL
17h 41m1 stop
LATAM Airlines Logo
11:05 pm - 5:48 pmSCL-CLT
18h 43m2 stops
$719LATAM Airlines
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Wed, Aug 20 - Wed, Aug 27
LATAM Airlines Logo
1:08 pm - 6:50 amCLT-SCL
17h 42m1 stop
LATAM Airlines Logo
11:55 pm - 1:25 pmSCL-CLT
14h 30m1 stop
$722LATAM Airlines
Find Deal
Tue, Sep 2 - Tue, Sep 9
LATAM Airlines Logo
10:00 am - 6:50 amCLT-SCL
20h 50m1 stop
LATAM Airlines Logo
8:40 pm - 8:55 amSCL-CLT
12h 15m1 stop
$731LATAM Airlines
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Wed, Aug 20 - Wed, Aug 27
American Airlines Logo
10:05 am - 7:55 amCLT-SCL
20h 50m1 stop
American Airlines Logo
9:55 pm - 9:18 amSCL-CLT
12h 23m1 stop
$734American Airlines
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Mon, Sep 15 - Mon, Sep 29
American Airlines Logo
10:05 am - 7:55 amCLT-SCL
20h 50m1 stop
American Airlines Logo
9:55 pm - 1:27 pmSCL-CLT
16h 32m2 stops
$738American Airlines
Find Deal
Wed, Oct 1 - Tue, Oct 14

LATAM Airlines flights from Charlotte to Santiago

Our best LATAM Airlines deals on Charlotte to Santiago flight tickets
LATAM Airlines
Aug 20
CLT1:09 pmCharlotte Douglas
17h 41m
1 stop
SCL6:50 amSantiago Arturo Merino Benitez
Aug 27
SCL11:05 pmSantiago Arturo Merino Benitez
18h 43m
2 stops
CLT5:48 pmCharlotte Douglas
$719
Find similar
LATAM Airlines
Sep 2
CLT1:08 pmCharlotte Douglas
17h 42m
1 stop
SCL6:50 amSantiago Arturo Merino Benitez
Sep 9
SCL11:55 pmSantiago Arturo Merino Benitez
14h 30m
1 stop
CLT1:25 pmCharlotte Douglas
$722
Find similar
LATAM Airlines
Aug 20
CLT10:00 amCharlotte Douglas
20h 50m
1 stop
SCL6:50 amSantiago Arturo Merino Benitez
Aug 27
SCL8:40 pmSantiago Arturo Merino Benitez
12h 15m
1 stop
CLT8:55 amCharlotte Douglas
$731
Find similar

Copa Airlines flights from Charlotte to Santiago

Our best Copa Airlines deals on Charlotte to Santiago flight tickets
Copa Airlines
Aug 1
CLT6:00 amCharlotte Douglas
23h 02m
2 stops
SCL5:02 amSantiago Arturo Merino Benitez
Aug 15
SCL11:29 amSantiago Arturo Merino Benitez
22h 18m
2 stops
CLT9:47 amCharlotte Douglas
$1,456
Find similar
Copa Airlines
Aug 1
CLT10:29 amCharlotte Douglas
18h 33m
2 stops
SCL5:02 amSantiago Arturo Merino Benitez
Aug 14
SCL2:26 amSantiago Arturo Merino Benitez
31h 21m
2 stops
CLT9:47 amCharlotte Douglas
$1,798
Find similar
Copa Airlines
Aug 1
CLT7:40 pmCharlotte Douglas
27h 28m
2 stops
SCL11:08 pmSantiago Arturo Merino Benitez
Aug 14
SCL2:26 amSantiago Arturo Merino Benitez
31h 21m
2 stops
CLT9:47 amCharlotte Douglas
$2,100
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Charlotte to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Charlotte to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 10/27

6:40 am-5:30 am

2 stops21h 50m

Santiago Arturo Merino Benitez

Sat 11/1

4:25 pm-1:23 pm

2 stops21h 58m

$582

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 9/1

6:00 am-4:15 am

2 stops22h 15m

Santiago Arturo Merino Benitez

Sat 9/6

2:30 pm-12:23 pm

2 stops21h 53m

$587

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 10/27

1:28 pm-12:15 pm

3 stops21h 47m

Santiago Arturo Merino Benitez

Sat 11/1

9:10 pm-1:23 pm

2 stops17h 13m

$590

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 9/1

1:43 pm-11:20 am

3 stops21h 37m

Santiago Arturo Merino Benitez

Fri 9/5

12:35 am-12:23 pm

3 stops35h 48m

$595

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 9/1

1:43 pm-1:45 pm

2 stops24h 02m

Santiago Arturo Merino Benitez

Sun 9/7

9:15 pm-12:23 pm

2 stops16h 08m

$596

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 8/20

1:09 pm-6:50 am

1 stop17h 41m

Santiago Arturo Merino Benitez

Wed 8/27

11:05 pm-5:48 pm

2 stops18h 43m

$719

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Tue 9/2

1:08 pm-6:50 am

1 stop17h 42m

Santiago Arturo Merino Benitez

Tue 9/9

11:55 pm-1:25 pm

1 stop14h 30m

$722

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 8/20

10:00 am-6:50 am

1 stop20h 50m

Santiago Arturo Merino Benitez

Wed 8/27

8:40 pm-8:55 am

1 stop12h 15m

$731

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 9/15

10:05 am-7:55 am

1 stop20h 50m

Santiago Arturo Merino Benitez

Mon 9/29

9:55 pm-9:18 am

1 stop12h 23m

$734

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 10/1

10:05 am-7:55 am

1 stop20h 50m

Santiago Arturo Merino Benitez

Tue 10/14

9:55 pm-1:27 pm

2 stops16h 32m

$738

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Charlotte to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Charlotte and Santiago?

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Charlotte to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $828. If you don’t want to visit Santiago in September, then you should wait until February to fly from Charlotte, when ticket prices are also cheap, with an average price of $857.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $841. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Sunday is $1,002.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Charlotte to Santiago when you can find flight prices for as low as $895. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,147 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Charlotte when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $944 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Charlotte for as low as $794 on momondo.

When to book flights from Charlotte to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Charlotte to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charlotte to Santiago (CLT to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charlotte to Santiago

Best Price Found

$243

Fastest flight time

15h 40m

Direct flights

None

Airports in Santiago

1 airport
The best one-way flight to Santiago from Charlotte in the past 72 hours is $243. The best round-trip flight deal from Charlotte to Santiago found on momondo in the last 72 hours is $582.
The fastest flight from Charlotte to Santiago takes 15h 40m
There are no direct flights from Charlotte to Santiago. Popular non-direct route for this connection is Charlotte Douglas Airport - Santiago Arturo Merino Benitez Airport.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)
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  • How far is Charlotte Douglas to Santiago Arturo Merino Benitez by plane?

    The distance between Charlotte Douglas and Santiago Arturo Merino Benitez is about 4787.2 mi. 17h 41m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Charlotte Douglas Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Charlotte Douglas Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Charlotte Douglas Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Charlotte Douglas Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Charlotte Douglas Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Charlotte to Santiago?

Best airlines flying from Charlotte to Santiago

Compare and see reviews for airlines that fly from Charlotte to Santiago with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $748Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $752Free CancellationRating
8.0
7,981 reviews
Search Delta flights
LATAM AirlinesPriceFrom $788Free CancellationRating
7.5
1,822 reviews
Search LATAM Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Charlotte to Santiago?

Finding the right flight to Santiago from Charlotte is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santiago quick and easy, saving you time and money.

Can I find flights from Charlotte to Santiago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago from Charlotte with this policy.

How can momondo help me find flights from Charlotte to Santiago?

momondo helps you find the best flight between Charlotte and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Charlotte to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Charlotte to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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