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Cheap flights from Charlotte to Santiago from $254

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charlotte to Santiago departing on 3/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Charlotte to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
1:20 pm - 10:39 am
CLT
-
SCL
20h 19m
2 stops
Multiple Airlines Logo
5:50 am - 12:07 pm
SCL
-
CLT
31h 17m
2 stops
$561Multiple Airlines
Wed, Mar 18 - Wed, Mar 25
Multiple Airlines Logo
10:42 am - 10:15 pm
CLT
-
SCL
34h 33m
2 stops
Multiple Airlines Logo
10:35 am - 12:07 pm
SCL
-
CLT
26h 32m
1 stop
$574Multiple Airlines
Wed, Mar 18 - Wed, Mar 25
Multiple Airlines Logo
10:55 am - 2:30 pm
CLT
-
SCL
26h 35m
2 stops
Multiple Airlines Logo
11:00 pm - 12:25 am
SCL
-
CLT
25h 25m
1 stop
$577Multiple Airlines
Wed, Apr 1 - Mon, Apr 6
Multiple Airlines Logo
3:12 pm - 2:40 pm
CLT
-
SCL
46h 28m
3 stops
Multiple Airlines Logo
5:50 am - 12:07 pm
SCL
-
CLT
31h 17m
2 stops
$586Multiple Airlines
Wed, Mar 18 - Wed, Mar 25
Multiple Airlines Logo
6:00 am - 5:30 am
CLT
-
SCL
23h 30m
2 stops
Multiple Airlines Logo
11:00 pm - 1:43 pm
SCL
-
CLT
14h 43m
1 stop
$595Multiple Airlines
Sat, Apr 11 - Sat, Apr 18
Multiple Airlines Logo
8:55 am - 4:16 am
CLT
-
SCL
19h 21m
2 stops
Multiple Airlines Logo
11:35 am - 2:13 pm
SCL
-
CLT
26h 38m
2 stops
$599Multiple Airlines
Wed, Apr 22 - Mon, May 4
Multiple Airlines Logo
7:00 am - 2:40 pm
CLT
-
SCL
30h 40m
2 stops
Multiple Airlines Logo
4:50 pm - 2:13 pm
SCL
-
CLT
21h 23m
2 stops
$600Multiple Airlines
Mon, Mar 30 - Tue, Apr 28
Multiple Airlines Logo
7:00 am - 11:05 am
CLT
-
SCL
28h 05m
3 stops
Multiple Airlines Logo
11:35 am - 2:13 pm
SCL
-
CLT
26h 38m
2 stops
$608Multiple Airlines
Sat, Apr 11 - Sat, Apr 18
Multiple Airlines Logo
1:20 pm - 3:56 am
CLT
-
SCL
14h 36m
2 stops
Multiple Airlines Logo
12:40 am - 12:07 pm
SCL
-
CLT
35h 27m
3 stops
$616Multiple Airlines
Mon, Apr 6 - Sat, Apr 11
Multiple Airlines Logo
7:00 am - 2:30 pm
CLT
-
SCL
30h 30m
2 stops
Multiple Airlines Logo
3:42 pm - 7:48 pm
SCL
-
CLT
28h 06m
3 stops
$618Multiple Airlines
Wed, Apr 1 - Mon, Apr 6

LATAM Airlines flights from Charlotte to Santiago

Our best LATAM Airlines deals on Charlotte to Santiago flight tickets
LATAM Airlines
Mar 12
CLT3:25 pmCharlotte Douglas
13h 30m
1 stop
SCL5:55 amSantiago Arturo Merino Benitez
Mar 23
SCL10:40 pmSantiago Arturo Merino Benitez
17h 05m
1 stop
CLT2:45 pmCharlotte Douglas
$763
LATAM Airlines
Mar 30
CLT3:26 pmCharlotte Douglas
15h 24m
1 stop
SCL7:50 amSantiago Arturo Merino Benitez
Apr 28
SCL10:55 pmSantiago Arturo Merino Benitez
15h 45m
1 stop
CLT2:40 pmCharlotte Douglas
$768
LATAM Airlines
Mar 12
CLT3:25 pmCharlotte Douglas
13h 30m
1 stop
SCL5:55 amSantiago Arturo Merino Benitez
Mar 23
SCL10:40 pmSantiago Arturo Merino Benitez
17h 05m
1 stop
CLT2:45 pmCharlotte Douglas
$769

momondo Fare Finder

 
Customize your flight search to find flights from Charlotte to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Charlotte to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 3/18

1:20 pm-10:39 am

2 stops20h 19m

Santiago Arturo Merino Benitez

Wed 3/25

5:50 am-12:07 pm

2 stops31h 17m

$561

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 3/18

10:42 am-10:15 pm

2 stops34h 33m

Santiago Arturo Merino Benitez

Wed 3/25

10:35 am-12:07 pm

1 stop26h 32m

$574

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 4/1

10:55 am-2:30 pm

2 stops26h 35m

Santiago Arturo Merino Benitez

Mon 4/6

11:00 pm-12:25 am

1 stop25h 25m

$577

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 3/18

3:12 pm-2:40 pm

3 stops46h 28m

Santiago Arturo Merino Benitez

Wed 3/25

5:50 am-12:07 pm

2 stops31h 17m

$586

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Sat 4/11

6:00 am-5:30 am

2 stops23h 30m

Santiago Arturo Merino Benitez

Sat 4/18

11:00 pm-1:43 pm

1 stop14h 43m

$595

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 4/22

8:55 am-4:16 am

2 stops19h 21m

Santiago Arturo Merino Benitez

Mon 5/4

11:35 am-2:13 pm

2 stops26h 38m

$599

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 3/30

7:00 am-2:40 pm

2 stops30h 40m

Santiago Arturo Merino Benitez

Tue 4/28

4:50 pm-2:13 pm

2 stops21h 23m

$600

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Sat 4/11

7:00 am-11:05 am

3 stops28h 05m

Santiago Arturo Merino Benitez

Sat 4/18

11:35 am-2:13 pm

2 stops26h 38m

$608

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 4/6

1:20 pm-3:56 am

2 stops14h 36m

Santiago Arturo Merino Benitez

Sat 4/11

12:40 am-12:07 pm

3 stops35h 27m

$616

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 4/1

7:00 am-2:30 pm

2 stops30h 30m

Santiago Arturo Merino Benitez

Mon 4/6

3:42 pm-7:48 pm

3 stops28h 06m

$618

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Charlotte to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, November is the cheapest month to fly from Charlotte to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $796. If you don’t want to visit Santiago in November, then you should wait until September to fly from Charlotte, when ticket prices are also cheap, with an average price of $828.

How have Charlotte to Santiago flight prices changed over time?

When to book flights from Charlotte to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Charlotte to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charlotte to Santiago (CLT to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charlotte to Santiago

Fastest flight time

15h 24m

Direct flights

None
The fastest flight from Charlotte to Santiago takes 15h 24m
There are no direct flights from Charlotte to Santiago. There are no popular flight routes from Charlotte to Santiago.
Search flight deals

  • How far is Charlotte Douglas to Santiago Arturo Merino Benitez by plane?

    The distance between Charlotte Douglas and Santiago Arturo Merino Benitez is about 4787.2 mi. 15h 24m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Charlotte Douglas Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Charlotte Douglas Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Charlotte Douglas Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Charlotte Douglas Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Charlotte Douglas Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Charlotte to Santiago?

Best airlines flying from Charlotte to Santiago

Compare and see reviews for airlines that fly from Charlotte to Santiago with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $714Free CancellationRating
7.2
11,222 reviews
Search American Airlines flights
DeltaPriceFrom $754Free CancellationRating
7.9
8,146 reviews
Search Delta flights
LATAM AirlinesPriceFrom $754Free CancellationRating
7.5
1,918 reviews
Search LATAM Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Charlotte to Santiago?

Finding the right flight to Santiago from Charlotte is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santiago quick and easy, saving you time and money.

Can I find flights from Charlotte to Santiago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago from Charlotte with this policy.

How can momondo help me find flights from Charlotte to Santiago?

momondo helps you find the best flight between Charlotte and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Charlotte to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Charlotte to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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