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Cheap flights from Charlotte to Santiago from $253

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charlotte to Santiago departing on 1/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Charlotte to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:12 am - 4:15 am
CLT
-
SCL
17h 03m2 stops
Multiple Airlines Logo
11:55 pm - 8:29 pm
SCL
-
CLT
20h 34m2 stops
$574Multiple Airlines
Mon, May 4 - Mon, May 18
Multiple Airlines Logo
3:15 pm - 2:40 pm
CLT
-
SCL
45h 25m3 stops
Multiple Airlines Logo
11:24 am - 6:48 pm
SCL
-
CLT
33h 24m2 stops
$680Multiple Airlines
Sat, Jan 31 - Sat, Feb 7
Multiple Airlines Logo
3:15 pm - 2:40 pm
CLT
-
SCL
45h 25m3 stops
Multiple Airlines Logo
11:24 am - 6:48 pm
SCL
-
CLT
33h 24m2 stops
$681Multiple Airlines
Sat, Jan 31 - Sat, Feb 7
LATAM Airlines Logo
2:31 pm - 6:55 am
CLT
-
SCL
14h 24m1 stop
LATAM Airlines Logo
11:30 pm - 1:39 pm
SCL
-
CLT
16h 09m1 stop
$684LATAM Airlines
Wed, Jan 21 - Wed, Jan 28
LATAM Airlines Logo
2:25 pm - 7:00 am
CLT
-
SCL
14h 35m2 stops
LATAM Airlines Logo
11:30 pm - 1:39 pm
SCL
-
CLT
16h 09m1 stop
$689LATAM Airlines
Wed, Jan 21 - Wed, Jan 28
LATAM Airlines Logo
2:10 pm - 6:55 am
CLT
-
SCL
14h 45m1 stop
LATAM Airlines Logo
6:40 am - 11:50 pm
SCL
-
CLT
18h 10m2 stops
$699LATAM Airlines
Mon, Mar 2 - Mon, Mar 16
Multiple Airlines Logo
6:00 am - 2:40 pm
CLT
-
SCL
30h 40m2 stops
Multiple Airlines Logo
11:24 am - 6:48 pm
SCL
-
CLT
33h 24m2 stops
$703Multiple Airlines
Sat, Jan 31 - Sat, Feb 7
LATAM Airlines Logo
2:25 pm - 7:00 am
CLT
-
SCL
14h 35m2 stops
LATAM Airlines Logo
6:30 pm - 10:50 am
SCL
-
CLT
18h 20m2 stops
$704LATAM Airlines
Wed, Jan 21 - Wed, Jan 28
Multiple Airlines Logo
7:00 am - 2:40 pm
CLT
-
SCL
29h 40m2 stops
Multiple Airlines Logo
11:24 am - 6:48 pm
SCL
-
CLT
33h 24m2 stops
$707Multiple Airlines
Sat, Jan 31 - Sat, Feb 7
Delta Logo
12:43 pm - 6:35 am
CLT
-
SCL
16h 52m2 stops
Delta Logo
8:45 am - 11:50 pm
SCL
-
CLT
16h 05m2 stops
$714Delta
Thu, Mar 19 - Tue, Mar 31

LATAM Airlines flights from Charlotte to Santiago

Our best LATAM Airlines deals on Charlotte to Santiago flight tickets
LATAM Airlines
Jan 21
CLT2:31 pmCharlotte Douglas
14h 24m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
Jan 28
SCL11:30 pmSantiago Arturo Merino Benitez
16h 09m
1 stop
CLT1:39 pmCharlotte Douglas
$684
Find similar
LATAM Airlines
Jan 21
CLT2:25 pmCharlotte Douglas
14h 35m
2 stops
SCL7:00 amSantiago Arturo Merino Benitez
Jan 28
SCL11:30 pmSantiago Arturo Merino Benitez
16h 09m
1 stop
CLT1:39 pmCharlotte Douglas
$689
Find similar
LATAM Airlines
Mar 2
CLT2:10 pmCharlotte Douglas
14h 45m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
Mar 16
SCL4:35 amSantiago Arturo Merino Benitez
20h 15m
2 stops
CLT11:50 pmCharlotte Douglas
$699
Find similar

United Airlines flights from Charlotte to Santiago

Our best United Airlines deals on Charlotte to Santiago flight tickets
United Airlines
Jan 21
CLT10:44 amCharlotte Douglas
20h 06m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
Jan 28
SCL10:45 pmSantiago Arturo Merino Benitez
14h 00m
1 stop
CLT10:45 amCharlotte Douglas
$719
Find similar
United Airlines
Jan 14
CLT4:45 pmCharlotte Douglas
14h 05m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Jan 21
SCL10:45 pmSantiago Arturo Merino Benitez
17h 28m
2 stops
CLT2:13 pmCharlotte Douglas
$765
Find similar
United Airlines
Jan 30
CLT7:01 amCharlotte Douglas
23h 49m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
Feb 6
SCL10:45 pmSantiago Arturo Merino Benitez
17h 28m
2 stops
CLT2:13 pmCharlotte Douglas
$799
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Charlotte to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Charlotte to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 5/4

11:12 am-4:15 am

2 stops17h 03m

Santiago Arturo Merino Benitez

Mon 5/18

11:55 pm-8:29 pm

2 stops20h 34m

$574

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Sat 1/31

3:15 pm-2:40 pm

3 stops45h 25m

Santiago Arturo Merino Benitez

Sat 2/7

11:24 am-6:48 pm

2 stops33h 24m

$680

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Sat 1/31

3:15 pm-2:40 pm

3 stops45h 25m

Santiago Arturo Merino Benitez

Sat 2/7

11:24 am-6:48 pm

2 stops33h 24m

$681

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 1/21

2:31 pm-6:55 am

1 stop14h 24m

Santiago Arturo Merino Benitez

Wed 1/28

11:30 pm-1:39 pm

1 stop16h 09m

$684

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 1/21

2:25 pm-7:00 am

2 stops14h 35m

Santiago Arturo Merino Benitez

Wed 1/28

11:30 pm-1:39 pm

1 stop16h 09m

$689

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 3/2

2:10 pm-6:55 am

1 stop14h 45m

Santiago Arturo Merino Benitez

Mon 3/16

6:40 am-11:50 pm

2 stops18h 10m

$699

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Sat 1/31

6:00 am-2:40 pm

2 stops30h 40m

Santiago Arturo Merino Benitez

Sat 2/7

11:24 am-6:48 pm

2 stops33h 24m

$703

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 1/21

2:25 pm-7:00 am

2 stops14h 35m

Santiago Arturo Merino Benitez

Wed 1/28

6:30 pm-10:50 am

2 stops18h 20m

$704

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Sat 1/31

7:00 am-2:40 pm

2 stops29h 40m

Santiago Arturo Merino Benitez

Sat 2/7

11:24 am-6:48 pm

2 stops33h 24m

$707

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Thu 3/19

12:43 pm-6:35 am

2 stops16h 52m

Santiago Arturo Merino Benitez

Tue 3/31

8:45 am-11:50 pm

2 stops16h 05m

$714

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Charlotte to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Charlotte and Santiago?

What is the cheapest month to fly to Santiago?

In general, November is the cheapest month to fly from Charlotte to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $796. If you don’t want to visit Santiago in November, then you should wait until September to fly from Charlotte, when ticket prices are also cheap, with an average price of $823.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $841. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Sunday is $1,002.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Charlotte to Santiago when you can find flight prices for as low as $895. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,147 per ticket.

When to book flights from Charlotte to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Charlotte to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charlotte to Santiago (CLT to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charlotte to Santiago

Fastest flight time

13h 30m

Direct flights

None
The fastest flight from Charlotte to Santiago takes 13h 30m
There are no direct flights from Charlotte to Santiago. There are no popular flight routes from Charlotte to Santiago.
Search flight deals

  • How far is Charlotte Douglas to Santiago Arturo Merino Benitez by plane?

    The distance between Charlotte Douglas and Santiago Arturo Merino Benitez is about 4787.2 mi. 13h 30m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Charlotte Douglas Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Charlotte Douglas Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Charlotte Douglas Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Charlotte Douglas Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Charlotte Douglas Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Charlotte to Santiago?

Best airlines flying from Charlotte to Santiago

Compare and see reviews for airlines that fly from Charlotte to Santiago with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $714Free CancellationRating
7.2
11,055 reviews
Search American Airlines flights
DeltaPriceFrom $752Free CancellationRating
7.9
8,009 reviews
Search Delta flights
LATAM AirlinesPriceFrom $754Free CancellationRating
7.5
1,893 reviews
Search LATAM Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Charlotte to Santiago?

Finding the right flight to Santiago from Charlotte is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santiago quick and easy, saving you time and money.

Can I find flights from Charlotte to Santiago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago from Charlotte with this policy.

How can momondo help me find flights from Charlotte to Santiago?

momondo helps you find the best flight between Charlotte and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Charlotte to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Charlotte to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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