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Cheap flights from Charleston to Santiago de los Caballeros from $337

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Santiago de los Caballeros departing on 10/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Charleston to Santiago de los Caballeros

Cheap round-trip flights

Spirit Airlines Logo
10:30 am - 11:05 amCHS-STI
24h 35m1 stop
Spirit Airlines Logo
12:10 pm - 9:25 amSTI-CHS
21h 15m1 stop
$337Spirit Airlines
Find Deal
Mon, Oct 27 - Thu, Oct 30
Spirit Airlines Logo
5:03 pm - 11:05 amCHS-STI
18h 02m2 stops
Spirit Airlines Logo
12:10 pm - 9:25 amSTI-CHS
21h 15m1 stop
$387Spirit Airlines
Find Deal
Mon, Oct 27 - Thu, Oct 30
JetBlue Logo
11:10 am - 6:04 pmCHS-STI
6h 54m1 stop
JetBlue Logo
7:14 pm - 10:25 amSTI-CHS
15h 11m1 stop
$397JetBlue
Find Deal
Tue, Sep 16 - Fri, Sep 26
Logo
10:10 am - 11:03 amCHS-STI
24h 53m1 stop
Logo
12:10 pm - 8:37 amSTI-CHS
20h 27m2 stops
$410
Find Deal
Fri, Sep 19 - Mon, Sep 29
JetBlue Logo
11:10 am - 6:04 pmCHS-STI
6h 54m1 stop
JetBlue Logo
5:15 am - 7:37 pmSTI-CHS
14h 22m2 stops
$425JetBlue
Find Deal
Tue, Sep 16 - Fri, Sep 26
Delta Logo
6:00 am - 7:11 pmCHS-STI
13h 11m1 stop
Delta Logo
6:11 am - 4:57 pmSTI-CHS
10h 46m1 stop
$429Delta
Find Deal
Tue, Sep 16 - Fri, Sep 26
Delta Logo
6:00 am - 12:40 pmCHS-STI
6h 40m1 stop
Delta Logo
8:40 pm - 1:49 pmSTI-CHS
17h 09m2 stops
$433Delta
Find Deal
Tue, Sep 16 - Fri, Sep 26
American Airlines Logo
7:08 am - 12:27 pmCHS-STI
5h 19m1 stop
American Airlines Logo
1:29 pm - 11:37 pmSTI-CHS
10h 08m1 stop
$434American Airlines
Find Deal
Wed, Sep 17 - Sun, Sep 28
Logo
6:08 pm - 11:03 amCHS-STI
16h 55m3 stops
Logo
12:10 pm - 8:37 amSTI-CHS
20h 27m2 stops
$562
Find Deal
Fri, Sep 19 - Mon, Sep 29
American Airlines Logo
5:10 am - 8:49 pmCHS-STI
14h 39m2 stops
American Airlines Logo
7:00 am - 11:56 pmSTI-CHS
17h 56m2 stops
$940American Airlines
Find Deal
Sat, Nov 22 - Sat, Nov 29

Delta flights from Charleston to Santiago de los Caballeros

Our best Delta deals on Charleston to Santiago de los Caballeros flight tickets
Delta
Sep 16
CHS6:00 amCharleston
13h 11m
1 stop
STI7:11 pmSantiago de los Caballeros
Sep 26
STI6:11 amSantiago de los Caballeros
10h 46m
1 stop
CHS4:57 pmCharleston
$429
Find similar
Delta
Sep 16
CHS6:00 amCharleston
6h 40m
1 stop
STI12:40 pmSantiago de los Caballeros
Sep 26
STI8:40 pmSantiago de los Caballeros
17h 09m
2 stops
CHS1:49 pmCharleston
$433
Find similar
Delta
Nov 22
CHS11:45 amCharleston
12h 41m
1 stop
STI1:26 amSantiago de los Caballeros
Nov 29
STI9:59 pmSantiago de los Caballeros
13h 58m
1 stop
CHS10:57 amCharleston
$538
Find similar

JetBlue flights from Charleston to Santiago de los Caballeros

Our best JetBlue deals on Charleston to Santiago de los Caballeros flight tickets
JetBlue
Sep 16
CHS11:10 amCharleston
6h 54m
1 stop
STI6:04 pmSantiago de los Caballeros
Sep 26
STI7:14 pmSantiago de los Caballeros
15h 11m
1 stop
CHS10:25 amCharleston
$397
Find similar
JetBlue
Sep 16
CHS11:10 amCharleston
6h 54m
1 stop
STI6:04 pmSantiago de los Caballeros
Sep 26
STI5:15 amSantiago de los Caballeros
14h 22m
2 stops
CHS7:37 pmCharleston
$425
Find similar
JetBlue
Oct 8
CHS7:00 pmCharleston
7h 16m
1 stop
STI2:16 amSantiago de los Caballeros
Oct 10
STI3:20 amSantiago de los Caballeros
14h 45m
1 stop
CHS6:05 pmCharleston
$443
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 7, 2025.
Use the filters below to find and compare flights from Charleston to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Mon 10/27

10:30 am-11:05 am

1 stop24h 35m

Santiago de los Caballeros

Thu 10/30

12:10 pm-9:25 am

1 stop21h 15m

$337

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Mon 10/27

5:03 pm-11:05 am

2 stops18h 02m

Santiago de los Caballeros

Thu 10/30

12:10 pm-9:25 am

1 stop21h 15m

$387

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Tue 9/16

11:10 am-6:04 pm

1 stop6h 54m

Santiago de los Caballeros

Fri 9/26

7:14 pm-10:25 am

1 stop15h 11m

$397

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Fri 9/19

10:10 am-11:03 am

1 stop24h 53m

Santiago de los Caballeros

Mon 9/29

12:10 pm-8:37 am

2 stops20h 27m

$410

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Tue 9/16

11:10 am-6:04 pm

1 stop6h 54m

Santiago de los Caballeros

Fri 9/26

5:15 am-7:37 pm

2 stops14h 22m

$425

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Tue 9/16

6:00 am-7:11 pm

1 stop13h 11m

Santiago de los Caballeros

Fri 9/26

6:11 am-4:57 pm

1 stop10h 46m

$429

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Tue 9/16

6:00 am-12:40 pm

1 stop6h 40m

Santiago de los Caballeros

Fri 9/26

8:40 pm-1:49 pm

2 stops17h 09m

$433

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Wed 9/17

7:08 am-12:27 pm

1 stop5h 19m

Santiago de los Caballeros

Sun 9/28

1:29 pm-11:37 pm

1 stop10h 08m

$434

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Fri 9/19

6:08 pm-11:03 am

3 stops16h 55m

Santiago de los Caballeros

Mon 9/29

12:10 pm-8:37 am

2 stops20h 27m

$562

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Sat 11/22

5:10 am-8:49 pm

2 stops14h 39m

Santiago de los Caballeros

Sat 11/29

7:00 am-11:56 pm

2 stops17h 56m

$940

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Charleston to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santiago de los Caballeros?

The cheapest day to depart from Charleston to Santiago de los Caballeros is on a Saturday when prices can be found for as low as $501. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Charleston to Santiago de los Caballeros for around $946.

What is the cheapest time of day to depart on your flight to Santiago de los Caballeros?

Our data shows that the cheapest Charleston to Santiago de los Caballeros flights are usually those with departure times in the afternoon. Our users have found flights to Santiago de los Caballeros in the afternoon for as low as $386. In the morning is when there is more demand to fly to Santiago de los Caballeros, so prices are often more expensive at around $585 per ticket.

When to book flights from Charleston to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to Santiago de los Caballeros (CHS to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Santiago de los Caballeros

Best Price Found

$337

Fastest flight time

5h 19m

Direct flights

None

Airports in Santiago de los Caballeros

1 airport
The best flight deal from Charleston to Santiago de los Caballeros found on momondo in the last 72 hours is $337
The fastest flight from Charleston to Santiago de los Caballeros takes 5h 19m
There are no direct flights from Charleston to Santiago de los Caballeros. Popular non-direct route for this connection is Charleston Airport - Santiago de los Caballeros Airport.
There is 1 airport near Santiago de los Caballeros: Santiago de los Caballeros (STI)
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  • How far is Charleston to Santiago de los Caballeros by plane?

    Charleston and Santiago de los Caballeros are 1082.3 mi apart from one another. In terms of flight time, this usually takes a little over 5h 19m.

  • When did momondo last update prices for flights from Charleston Airport to Santiago de los Caballeros Airport?

    Prices for flights from Charleston Airport to Santiago de los Caballeros Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Charleston Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Charleston Airport to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charleston Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The required travel and health documents for your Santiago de los Caballeros Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago de los Caballeros Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Charleston to Santiago de los Caballeros?

Best airlines flying from Charleston to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Charleston to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $371Free CancellationRating
7.2
2,915 reviews
Search JetBlue flights
American AirlinesPriceFrom $500Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Santiago de los Caballeros?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Charleston to Santiago de los Caballeros for you.

Can I find flights from Charleston to Santiago de los Caballeros with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago de los Caballeros from Charleston which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Charleston to Santiago de los Caballeros?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santiago de los Caballeros from Charleston.

I’m not ready to book a flight from Charleston to Santiago de los Caballeros right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charleston to Santiago de los Caballeros now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago de los Caballeros and let you know when they change.

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