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Cheap flights from Charleston to Santiago de los Caballeros from $118

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Santiago de los Caballeros departing on 4/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Charleston to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
8:07 am - 2:35 pm
CHS
-
STI
6h 28m
1 stop
Spirit Airlines Logo
3:40 pm - 10:41 pm
STI
-
CHS
7h 01m
1 stop
$267Spirit Airlines
Wed, Apr 8 - Sat, Apr 18
Spirit Airlines Logo
8:07 am - 2:35 pm
CHS
-
STI
6h 28m
1 stop
Spirit Airlines Logo
3:43 pm - 10:33 pm
STI
-
CHS
6h 50m
1 stop
$285Spirit Airlines
Sun, Apr 12 - Tue, Apr 14
Spirit Airlines Logo
8:07 am - 2:35 pm
CHS
-
STI
6h 28m
1 stop
Spirit Airlines Logo
3:43 pm - 10:33 pm
STI
-
CHS
6h 50m
1 stop
$297Spirit Airlines
Sun, Apr 12 - Tue, Apr 14
Spirit Airlines Logo
8:07 am - 2:35 pm
CHS
-
STI
6h 28m
1 stop
Spirit Airlines Logo
3:43 pm - 10:33 pm
STI
-
CHS
6h 50m
1 stop
$300Spirit Airlines
Wed, Mar 25 - Mon, Mar 30
Spirit Airlines Logo
8:07 am - 2:35 pm
CHS
-
STI
6h 28m
1 stop
Spirit Airlines Logo
3:43 pm - 10:33 pm
STI
-
CHS
6h 50m
1 stop
$302Spirit Airlines
Wed, Mar 25 - Mon, Mar 30
Spirit Airlines Logo
8:07 am - 1:49 am
CHS
-
STI
17h 42m
1 stop
Spirit Airlines Logo
3:40 pm - 10:41 pm
STI
-
CHS
7h 01m
1 stop
$318Spirit Airlines
Wed, Apr 8 - Sat, Apr 18
American Airlines Logo
4:46 pm - 12:23 pm
CHS
-
STI
19h 37m
2 stops
American Airlines Logo
1:32 pm - 11:38 am
STI
-
CHS
22h 06m
2 stops
$319American Airlines
Wed, Apr 15 - Mon, Apr 20
American Airlines Logo
8:13 pm - 1:31 pm
CHS
-
STI
16h 18m
1 stop
American Airlines Logo
8:00 am - 7:22 pm
STI
-
CHS
12h 22m
1 stop
$322American Airlines
Fri, Feb 27 - Tue, Mar 3
American Airlines Logo
6:45 pm - 12:30 pm
CHS
-
STI
17h 45m
2 stops
American Airlines Logo
7:00 am - 10:26 am
STI
-
CHS
27h 26m
1 stop
$326American Airlines
Wed, Mar 25 - Mon, Mar 30
American Airlines Logo
11:04 am - 12:23 pm
CHS
-
STI
25h 19m
1 stop
American Airlines Logo
1:32 pm - 10:24 am
STI
-
CHS
20h 52m
1 stop
$329American Airlines
Wed, Apr 15 - Mon, Apr 20

Spirit Airlines flights from Charleston to Santiago de los Caballeros

Our best Spirit Airlines deals on Charleston to Santiago de los Caballeros flight tickets
Spirit Airlines
Apr 8
CHS8:07 amCharleston
6h 28m
1 stop
STI2:35 pmSantiago de los Caballeros
Apr 18
STI3:40 pmSantiago de los Caballeros
7h 01m
1 stop
CHS10:41 pmCharleston
$267
Spirit Airlines
Apr 12
CHS8:07 amCharleston
6h 28m
1 stop
STI2:35 pmSantiago de los Caballeros
Apr 14
STI3:43 pmSantiago de los Caballeros
6h 50m
1 stop
CHS10:33 pmCharleston
$285
Spirit Airlines
Apr 12
CHS8:07 amCharleston
6h 28m
1 stop
STI2:35 pmSantiago de los Caballeros
Apr 14
STI3:43 pmSantiago de los Caballeros
6h 50m
1 stop
CHS10:33 pmCharleston
$297

American Airlines flights from Charleston to Santiago de los Caballeros

Our best American Airlines deals on Charleston to Santiago de los Caballeros flight tickets
American Airlines
Apr 15
CHS4:46 pmCharleston
19h 37m
2 stops
STI12:23 pmSantiago de los Caballeros
Apr 20
STI1:32 pmSantiago de los Caballeros
22h 06m
2 stops
CHS11:38 amCharleston
$319
American Airlines
Feb 27
CHS8:13 pmCharleston
16h 18m
1 stop
STI1:31 pmSantiago de los Caballeros
Mar 3
STI8:00 amSantiago de los Caballeros
12h 22m
1 stop
CHS7:22 pmCharleston
$322
American Airlines
Mar 25
CHS6:45 pmCharleston
17h 45m
2 stops
STI12:30 pmSantiago de los Caballeros
Mar 30
STI7:00 amSantiago de los Caballeros
27h 26m
1 stop
CHS10:26 amCharleston
$326

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Charleston to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Wed 4/8

8:07 am-2:35 pm

1 stop6h 28m

Santiago de los Caballeros

Sat 4/18

3:40 pm-10:41 pm

1 stop7h 01m

$267

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Sun 4/12

8:07 am-2:35 pm

1 stop6h 28m

Santiago de los Caballeros

Tue 4/14

3:43 pm-10:33 pm

1 stop6h 50m

$285

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Sun 4/12

8:07 am-2:35 pm

1 stop6h 28m

Santiago de los Caballeros

Tue 4/14

3:43 pm-10:33 pm

1 stop6h 50m

$297

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Wed 3/25

8:07 am-2:35 pm

1 stop6h 28m

Santiago de los Caballeros

Mon 3/30

3:43 pm-10:33 pm

1 stop6h 50m

$300

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Wed 3/25

8:07 am-2:35 pm

1 stop6h 28m

Santiago de los Caballeros

Mon 3/30

3:43 pm-10:33 pm

1 stop6h 50m

$302

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Wed 4/8

8:07 am-1:49 am

1 stop17h 42m

Santiago de los Caballeros

Sat 4/18

3:40 pm-10:41 pm

1 stop7h 01m

$318

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Wed 4/15

4:46 pm-12:23 pm

2 stops19h 37m

Santiago de los Caballeros

Mon 4/20

1:32 pm-11:38 am

2 stops22h 06m

$319

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Fri 2/27

8:13 pm-1:31 pm

1 stop16h 18m

Santiago de los Caballeros

Tue 3/3

8:00 am-7:22 pm

1 stop12h 22m

$322

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Wed 3/25

6:45 pm-12:30 pm

2 stops17h 45m

Santiago de los Caballeros

Mon 3/30

7:00 am-10:26 am

1 stop27h 26m

$326

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Wed 4/15

11:04 am-12:23 pm

1 stop25h 19m

Santiago de los Caballeros

Mon 4/20

1:32 pm-10:24 am

1 stop20h 52m

$329

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Charleston to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Charleston to Santiago de los Caballeros flights?

You could potentially save up to 58% on your flight if you consider stops on a Charleston to Santiago de los Caballeros flight.

When to book flights from Charleston to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to Santiago de los Caballeros (CHS to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Santiago de los Caballeros

Fastest flight time

6h 28m

Direct flights

None
The fastest flight from Charleston to Santiago de los Caballeros takes 6h 28m
There are no direct flights from Charleston to Santiago de los Caballeros. There are no popular flight routes from Charleston to Santiago de los Caballeros.
Search flight deals

  • How far is Charleston to Santiago de los Caballeros by plane?

    Charleston and Santiago de los Caballeros are 1082.3 mi apart from one another. In terms of flight time, this usually takes a little over 6h 28m.

  • When did momondo last update prices for flights from Charleston Airport to Santiago de los Caballeros Airport?

    Prices for flights from Charleston Airport to Santiago de los Caballeros Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Charleston Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Charleston Airport to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charleston Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The required travel and health documents for your Santiago de los Caballeros Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago de los Caballeros Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Charleston to Santiago de los Caballeros?

Best airlines flying from Charleston to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Charleston to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $458Free CancellationRating
7.2
11,206 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Santiago de los Caballeros?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Charleston to Santiago de los Caballeros for you.

Can I find flights from Charleston to Santiago de los Caballeros with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago de los Caballeros from Charleston which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Charleston to Santiago de los Caballeros?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santiago de los Caballeros from Charleston.

I’m not ready to book a flight from Charleston to Santiago de los Caballeros right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charleston to Santiago de los Caballeros now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago de los Caballeros and let you know when they change.

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