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Cheap flights from Charleston to Santiago de los Caballeros from $196

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Santiago de los Caballeros departing on 5/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Charleston to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
8:09 pm - 9:13 pm
CHS
-
STI
25h 04m
1 stop
American Airlines Logo
1:21 pm - 11:56 pm
STI
-
CHS
10h 35m
1 stop
$412American Airlines
Fri, May 29 - Tue, Jun 2
Delta Logo
6:00 am - 7:29 pm
CHS
-
STI
13h 29m
1 stop
Delta Logo
6:00 am - 8:46 pm
STI
-
CHS
14h 46m
1 stop
$416Delta
Sat, May 16 - Mon, May 18
American Airlines Logo
8:09 pm - 9:13 pm
CHS
-
STI
25h 04m
1 stop
American Airlines Logo
3:38 pm - 12:08 pm
STI
-
CHS
20h 30m
2 stops
$417American Airlines
Fri, May 29 - Tue, Jun 2
Delta Logo
6:00 am - 7:29 pm
CHS
-
STI
13h 29m
1 stop
Delta Logo
8:59 pm - 12:10 pm
STI
-
CHS
15h 11m
2 stops
$421Delta
Sat, May 16 - Mon, May 18
American Airlines Logo
8:21 pm - 12:23 pm
CHS
-
STI
16h 02m
2 stops
American Airlines Logo
1:21 pm - 11:54 pm
STI
-
CHS
10h 33m
1 stop
$435American Airlines
Sun, May 17 - Sat, May 23
American Airlines Logo
6:00 am - 9:13 pm
CHS
-
STI
15h 13m
1 stop
American Airlines Logo
7:04 am - 11:59 pm
STI
-
CHS
16h 55m
1 stop
$438American Airlines
Tue, May 26 - Mon, Jun 8
American Airlines Logo
6:20 pm - 12:23 pm
CHS
-
STI
18h 03m
2 stops
American Airlines Logo
1:32 pm - 9:52 am
STI
-
CHS
20h 20m
2 stops
$441American Airlines
Sat, May 16 - Mon, May 18
Delta Logo
1:17 pm - 12:59 am
CHS
-
STI
11h 42m
2 stops
Delta Logo
6:00 am - 9:33 pm
STI
-
CHS
15h 33m
1 stop
$455Delta
Tue, May 26 - Mon, Jun 8
Delta Logo
5:55 pm - 12:59 am
CHS
-
STI
7h 04m
1 stop
Delta Logo
6:00 am - 5:12 pm
STI
-
CHS
11h 12m
1 stop
$456Delta
Sat, May 16 - Mon, May 18
Delta Logo
7:30 am - 7:29 pm
CHS
-
STI
11h 59m
2 stops
Delta Logo
8:59 pm - 3:49 pm
STI
-
CHS
18h 50m
2 stops
$461Delta
Sat, May 16 - Mon, May 18

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American Airlines flights from Charleston to Santiago de los Caballeros

Our best American Airlines deals on Charleston to Santiago de los Caballeros flight tickets
American Airlines
May 29
CHS8:09 pmCharleston
25h 04m
1 stop
STI9:13 pmSantiago de los Caballeros
Jun 2
STI1:21 pmSantiago de los Caballeros
10h 35m
1 stop
CHS11:56 pmCharleston
$412
American Airlines
May 29
CHS8:09 pmCharleston
25h 04m
1 stop
STI9:13 pmSantiago de los Caballeros
Jun 2
STI3:38 pmSantiago de los Caballeros
20h 30m
2 stops
CHS12:08 pmCharleston
$417
American Airlines
May 17
CHS8:21 pmCharleston
16h 02m
2 stops
STI12:23 pmSantiago de los Caballeros
May 23
STI1:21 pmSantiago de los Caballeros
10h 33m
1 stop
CHS11:54 pmCharleston
$435

Delta flights from Charleston to Santiago de los Caballeros

Our best Delta deals on Charleston to Santiago de los Caballeros flight tickets
Delta
May 16
CHS6:00 amCharleston
13h 29m
1 stop
STI7:29 pmSantiago de los Caballeros
May 18
STI6:00 amSantiago de los Caballeros
14h 46m
1 stop
CHS8:46 pmCharleston
$416
Delta
May 16
CHS6:00 amCharleston
13h 29m
1 stop
STI7:29 pmSantiago de los Caballeros
May 18
STI8:59 pmSantiago de los Caballeros
15h 11m
2 stops
CHS12:10 pmCharleston
$421
Delta
May 26
CHS1:17 pmCharleston
11h 42m
2 stops
STI12:59 amSantiago de los Caballeros
Jun 8
STI6:00 amSantiago de los Caballeros
15h 33m
1 stop
CHS9:33 pmCharleston
$455

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 5, 2026.
Use the filters below to find and compare flights from Charleston to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Fri 5/29

8:09 pm-9:13 pm

1 stop25h 04m

Santiago de los Caballeros

Tue 6/2

1:21 pm-11:56 pm

1 stop10h 35m

$412

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Sat 5/16

6:00 am-7:29 pm

1 stop13h 29m

Santiago de los Caballeros

Mon 5/18

6:00 am-8:46 pm

1 stop14h 46m

$416

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Fri 5/29

8:09 pm-9:13 pm

1 stop25h 04m

Santiago de los Caballeros

Tue 6/2

3:38 pm-12:08 pm

2 stops20h 30m

$417

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Sat 5/16

6:00 am-7:29 pm

1 stop13h 29m

Santiago de los Caballeros

Mon 5/18

8:59 pm-12:10 pm

2 stops15h 11m

$421

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Sun 5/17

8:21 pm-12:23 pm

2 stops16h 02m

Santiago de los Caballeros

Sat 5/23

1:21 pm-11:54 pm

1 stop10h 33m

$435

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Tue 5/26

6:00 am-9:13 pm

1 stop15h 13m

Santiago de los Caballeros

Mon 6/8

7:04 am-11:59 pm

1 stop16h 55m

$438

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Sat 5/16

6:20 pm-12:23 pm

2 stops18h 03m

Santiago de los Caballeros

Mon 5/18

1:32 pm-9:52 am

2 stops20h 20m

$441

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Tue 5/26

1:17 pm-12:59 am

2 stops11h 42m

Santiago de los Caballeros

Mon 6/8

6:00 am-9:33 pm

1 stop15h 33m

$455
Quickest round-trip

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Sat 5/16

5:55 pm-12:59 am

1 stop7h 04m

Santiago de los Caballeros

Mon 5/18

6:00 am-5:12 pm

1 stop11h 12m

$456

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Sat 5/16

7:30 am-7:29 pm

2 stops11h 59m

Santiago de los Caballeros

Mon 5/18

8:59 pm-3:49 pm

2 stops18h 50m

$461

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Charleston to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Charleston to Santiago de los Caballeros flights?

You could potentially save up to 19% on your flight if you consider stops on a Charleston to Santiago de los Caballeros flight.

When to book flights from Charleston to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to Santiago de los Caballeros (CHS to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Santiago de los Caballeros

Fastest flight time

7h 04m

Direct flights

None
The fastest flight from Charleston to Santiago de los Caballeros takes 7h 04m
There are no direct flights from Charleston to Santiago de los Caballeros. There are no popular flight routes from Charleston to Santiago de los Caballeros.
Search flight deals

Frequently asked questions about flying from Charleston to Santiago de los Caballeros

  • How far is Charleston to Santiago de los Caballeros by plane?

    Charleston and Santiago de los Caballeros are 1082.3 mi apart from one another. In terms of flight time, this usually takes a little over 7h 04m.

  • When did momondo last update prices for flights from Charleston Airport to Santiago de los Caballeros Airport?

    Prices for flights from Charleston Airport to Santiago de los Caballeros Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Charleston Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Charleston Airport to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charleston Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The required travel and health documents for your Santiago de los Caballeros Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago de los Caballeros Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Charleston to Santiago de los Caballeros?

Best airlines flying from Charleston to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Charleston to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $458Free CancellationRating
7.1
11,667 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Santiago de los Caballeros?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Charleston to Santiago de los Caballeros for you.

Can I find flights from Charleston to Santiago de los Caballeros with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago de los Caballeros from Charleston which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Charleston to Santiago de los Caballeros?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santiago de los Caballeros from Charleston.

I’m not ready to book a flight from Charleston to Santiago de los Caballeros right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charleston to Santiago de los Caballeros now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago de los Caballeros and let you know when they change.

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