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Cheap flights from Charleston to Santiago de los Caballeros from $383

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Santiago de los Caballeros departing on 9/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Charleston to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:00 am - 2:35 pm
CHS
-
STI
7h 35m
1 stop
American Airlines Logo
3:15 pm - 10:45 am
STI
-
CHS
19h 30m
2 stops
$383American Airlines
Tue, Sep 8 - Thu, Sep 10
American Airlines Logo
7:00 am - 8:03 pm
CHS
-
STI
13h 03m
1 stop
American Airlines Logo
3:15 pm - 11:43 pm
STI
-
CHS
8h 28m
1 stop
$432American Airlines
Tue, Sep 8 - Thu, Sep 10
United Airlines Logo
7:00 am - 3:12 pm
CHS
-
STI
8h 12m
1 stop
United Airlines Logo
4:23 pm - 11:59 pm
STI
-
CHS
7h 36m
1 stop
$596United Airlines
Tue, Sep 22 - Wed, Sep 23
JetBlue Logo
7:00 pm - 11:51 pm
CHS
-
STI
4h 51m
1 stop
JetBlue Logo
8:40 pm - 9:59 am
STI
-
CHS
14h 19m
1 stop
$603JetBlue
Sat, Oct 31 - Tue, Nov 3

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American Airlines flights from Charleston to Santiago de los Caballeros

Our best American Airlines deals on Charleston to Santiago de los Caballeros flight tickets
American Airlines
Sep 8
CHS10:20 amCharleston
9h 43m
2 stops
STI8:03 pmSantiago de los Caballeros
Sep 10
STI3:15 pmSantiago de los Caballeros
21h 34m
2 stops
CHS12:49 pmCharleston
$383
American Airlines
Sep 8
CHS7:00 amCharleston
13h 03m
1 stop
STI8:03 pmSantiago de los Caballeros
Sep 10
STI3:15 pmSantiago de los Caballeros
8h 28m
1 stop
CHS11:43 pmCharleston
$432

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 28, 2026.
Use the filters below to find and compare flights from Charleston to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Tue 9/8

7:00 am-2:35 pm

1 stop7h 35m

Santiago de los Caballeros

Thu 9/10

3:15 pm-10:45 am

2 stops19h 30m

$383

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Tue 9/8

7:00 am-8:03 pm

1 stop13h 03m

Santiago de los Caballeros

Thu 9/10

3:15 pm-11:43 pm

1 stop8h 28m

$432
Quickest round-trip

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Tue 9/22

7:00 am-3:12 pm

1 stop8h 12m

Santiago de los Caballeros

Wed 9/23

4:23 pm-11:59 pm

1 stop7h 36m

$596

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Sat 10/31

7:00 pm-11:51 pm

1 stop4h 51m

Santiago de los Caballeros

Tue 11/3

8:40 pm-9:59 am

1 stop14h 19m

$603
Cheapest one-way

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Thu 7/2

8:13 pm-9:28 pm

1 stop25h 15m

$470
Quickest one-way

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Thu 7/2

4:52 pm-5:38 pm

2 stops24h 46m

$518

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Thu 7/2

8:20 pm-12:55 pm

3 stops40h 35m

$866

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Charleston to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Charleston to Santiago de los Caballeros flights?

You could potentially save up to 19% on your flight if you consider stops on a Charleston to Santiago de los Caballeros flight.

When to book flights from Charleston to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to Santiago de los Caballeros (CHS to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Santiago de los Caballeros

Fastest flight time

4h 51m

Direct flights

None
The fastest flight from Charleston to Santiago de los Caballeros takes 4h 51m
There are no direct flights from Charleston to Santiago de los Caballeros. There are no popular flight routes from Charleston to Santiago de los Caballeros.
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Frequently asked questions about flying from Charleston to Santiago de los Caballeros

  • How far is Charleston to Santiago de los Caballeros by plane?

    Charleston and Santiago de los Caballeros are 1082.3 mi apart from one another. In terms of flight time, this usually takes a little over 4h 51m.

  • When did momondo last update prices for flights from Charleston Airport to Santiago de los Caballeros Airport?

    Prices for flights from Charleston Airport to Santiago de los Caballeros Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Charleston Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Charleston Airport to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charleston Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The required travel and health documents for your Santiago de los Caballeros Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago de los Caballeros Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Charleston to Santiago de los Caballeros?

Best airlines flying from Charleston to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Charleston to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $414Free CancellationRating
7.1
11,774 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Santiago de los Caballeros?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Charleston to Santiago de los Caballeros for you.

Can I find flights from Charleston to Santiago de los Caballeros with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago de los Caballeros from Charleston which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Charleston to Santiago de los Caballeros?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santiago de los Caballeros from Charleston.

I’m not ready to book a flight from Charleston to Santiago de los Caballeros right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charleston to Santiago de los Caballeros now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago de los Caballeros and let you know when they change.

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1 adult
Tue 7/28
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