Cheap flights from Cali to Santiago from $220

In general, April is the cheapest month to fly from Cali to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $357. If you don’t want to visit Santiago in April, then you should wait until September to fly from Cali, when ticket prices are also cheap, with an average price of $368.

The cheapest day to depart on your flight to Santiago is on a Sunday when prices can be found for as low as $379. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Monday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Monday is $639.

In the morning is the cheapest time of day to fly from Cali to Santiago when you can find flight prices for as low as $398. Flying to Santiago in the morning is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Santiago, so prices are often more expensive at around $472 per ticket.

Fly from Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez for the best Cali Alfonso B. Aragon Intl - Santiago Arturo Merino Benitez flight prices

You are more likely to see cheaper flights to Santiago from Cali when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $396 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Cali for as low as $358 on momondo.

There is only 1 cabin class available to choose from on Cali to Santiago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Cali to Santiago.

As of September 2026, prices for Cali to Santiago flights are approximately 4% more expensive when compared to flights at the same time last year.

Historically, on average around 14% of flights between Cali and Santiago have experienced a delay on any given week. The average delay length over the past 12 months has been 168 minutes.

Generally, flights departing in the early afternoon tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

Saturday is statistically the day of the week which experiences the fewest number of delays on this flight route. Tuesday has historically seen more delays on average compared to the rest of the week.

According to our data, JetSMART have had the least number of delays on this route over the last 12 months; with about 14% of their flights experiencing any sort of delay.