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Cheap flights from Cali to Santiago from $188

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cali to Santiago departing on 3/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Cali to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetSMART Logo
9:35 pm - 4:17 am
CLO
-
SCL
5h 42mnonstop
JetSMART Logo
3:33 pm - 8:35 pm
SCL
-
CLO
6h 02mnonstop
$301JetSMART
Mon, Apr 13 - Mon, Apr 20
JetSMART Logo
8:40 pm - 4:22 am
CLO
-
SCL
5h 42mnonstop
JetSMART Logo
3:42 pm - 7:40 pm
SCL
-
CLO
5h 58mnonstop
$302JetSMART
Mon, Mar 16 - Mon, Mar 23
JetSMART Logo
8:40 pm - 4:22 am
CLO
-
SCL
5h 42mnonstop
JetSMART Logo
3:42 pm - 7:40 pm
SCL
-
CLO
5h 58mnonstop
$303JetSMART
Mon, Mar 16 - Mon, Mar 23
JetSMART Logo
8:35 pm - 4:17 am
CLO
-
SCL
5h 42mnonstop
JetSMART Logo
3:37 pm - 7:35 pm
SCL
-
CLO
5h 58mnonstop
$338JetSMART
Wed, Mar 18 - Wed, Mar 25
JetSMART Logo
2:11 pm - 2:03 pm
CLO
-
SCL
22h 52m1 stop
JetSMART Logo
3:33 pm - 8:35 pm
SCL
-
CLO
6h 02mnonstop
$339JetSMART
Tue, Apr 21 - Sun, Apr 26
JetSMART Logo
8:35 pm - 4:17 am
CLO
-
SCL
5h 42mnonstop
JetSMART Logo
3:33 pm - 8:35 pm
SCL
-
CLO
6h 02mnonstop
$340JetSMART
Fri, Mar 20 - Fri, Jun 19
JetSMART Logo
8:35 pm - 4:17 am
CLO
-
SCL
5h 42mnonstop
JetSMART Logo
3:37 pm - 7:35 pm
SCL
-
CLO
5h 58mnonstop
$341JetSMART
Fri, Mar 27 - Fri, Apr 3
JetSMART Logo
1:09 pm - 6:12 pm
CLO
-
SCL
27h 03m1 stop
JetSMART Logo
3:42 pm - 7:40 pm
SCL
-
CLO
5h 58mnonstop
$350JetSMART
Sat, Mar 7 - Mon, Mar 23
JetSMART Logo
8:40 pm - 4:22 am
CLO
-
SCL
5h 42mnonstop
JetSMART Logo
8:33 pm - 10:03 pm
SCL
-
CLO
27h 30m1 stop
$351JetSMART
Mon, Mar 16 - Mon, Mar 23
JetSMART Logo
9:35 pm - 4:17 am
CLO
-
SCL
5h 42mnonstop
JetSMART Logo
12:59 am - 2:43 pm
SCL
-
CLO
14h 44m1 stop
$352JetSMART
Mon, Apr 13 - Sun, Apr 19

JetSMART flights from Cali to Santiago

Our best JetSMART deals on Cali to Santiago flight tickets
JetSMART
Apr 13
CLO9:35 pmCali Alfonso B. Aragon Intl
5h 42m
SCL4:17 amSantiago Arturo Merino Benitez
Apr 20
SCL3:33 pmSantiago Arturo Merino Benitez
6h 02m
CLO8:35 pmCali Alfonso B. Aragon Intl
$301
Find similar
JetSMART
Mar 16
CLO8:40 pmCali Alfonso B. Aragon Intl
5h 42m
SCL4:22 amSantiago Arturo Merino Benitez
Mar 23
SCL3:42 pmSantiago Arturo Merino Benitez
5h 58m
CLO7:40 pmCali Alfonso B. Aragon Intl
$302
Find similar
JetSMART
Mar 16
CLO8:40 pmCali Alfonso B. Aragon Intl
5h 42m
SCL4:22 amSantiago Arturo Merino Benitez
Mar 23
SCL3:42 pmSantiago Arturo Merino Benitez
5h 58m
CLO7:40 pmCali Alfonso B. Aragon Intl
$303
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Cali to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Cali to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Mon 4/13

9:35 pm-4:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Mon 4/20

3:33 pm-8:35 pm

Nonstop6h 02m

$301

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Mon 3/16

8:40 pm-4:22 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Mon 3/23

3:42 pm-7:40 pm

Nonstop5h 58m

$302

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Mon 3/16

8:40 pm-4:22 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Mon 3/23

3:42 pm-7:40 pm

Nonstop5h 58m

$303

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Wed 3/18

8:35 pm-4:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Wed 3/25

3:37 pm-7:35 pm

Nonstop5h 58m

$338

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Tue 4/21

2:11 pm-2:03 pm

1 stop22h 52m

Santiago Arturo Merino Benitez

Sun 4/26

3:33 pm-8:35 pm

Nonstop6h 02m

$339

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Fri 3/20

8:35 pm-4:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Fri 6/19

3:33 pm-8:35 pm

Nonstop6h 02m

$340

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Fri 3/27

8:35 pm-4:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Fri 4/3

3:37 pm-7:35 pm

Nonstop5h 58m

$341

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Sat 3/7

1:09 pm-6:12 pm

1 stop27h 03m

Santiago Arturo Merino Benitez

Mon 3/23

3:42 pm-7:40 pm

Nonstop5h 58m

$350

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Mon 3/16

8:40 pm-4:22 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Mon 3/23

8:33 pm-10:03 pm

1 stop27h 30m

$351

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Mon 4/13

9:35 pm-4:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Sun 4/19

12:59 am-2:43 pm

1 stop14h 44m

$352

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Cali to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, May is the cheapest month to fly from Cali to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $363. If you don’t want to visit Santiago in May, then you should wait until June to fly from Cali, when ticket prices are also cheap, with an average price of $372.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Tuesday when prices can be found for as low as $405. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Wednesday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Wednesday is $487.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from Cali to Santiago when you can find flight prices for as low as $262. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Santiago, so prices are often more expensive at around $454 per ticket.

What is the cheapest Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez flight route?

Fly from Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez for the best Cali Alfonso B. Aragon Intl - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Cali when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $381 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Cali for as low as $345 on momondo.

What cabin class options are available on Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez flights?

There is only 1 cabin class available to choose from on Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Cali to Santiago flights?

No. A direct flight is the cheapest option for a flight between Cali to Santiago.

How have Cali to Santiago flight prices changed over time?

As of December 2025, prices for Cali to Santiago flights are approximately 39% more expensive when compared to flights at the same time last year.

When to book flights from Cali to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Cali to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Cali to Santiago (CLO to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cali to Santiago

Best Price Found

$225

Fastest flight time

5h 42m

Direct flights

Mon, Tue, Wed, Thu, Fri and Sat

Airports in Santiago

1 airport
The best one-way flight to Santiago from Cali in the past 72 hours is $225. The best round-trip flight deal from Cali to Santiago found on momondo in the last 72 hours is $338.
The fastest flight from Cali to Santiago takes 5h 42m
Direct flights go from Cali to Santiago on Monday, Tuesday, Wednesday, Thursday, Friday and Saturday. The only airline offering direct flights is JetSMART.
There is 1 airport in Santiago. From Cali there are direct flights to Santiago Arturo Merino Benitez (SCL).
Search flight deals

  • How far is Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez by plane?

    Cali Alfonso B. Aragon Intl and Santiago Arturo Merino Benitez are 2576.4 mi apart from one another. In terms of flight time, this usually takes a little over 5h 42m.

  • When did momondo last update prices for flights from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Cali to Santiago?

  • What is the most popular airline from Cali to Santiago?

Best airlines flying from Cali to Santiago

Compare and see reviews for airlines that fly from Cali to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $230Free CancellationRating
6.6
2,490 reviews
Search Avianca flights
JetSMARTPriceFrom $286Free CancellationRating
6.6
254 reviews
Search JetSMART flights

  • JetSMART Flights From Cali to Santiago

    JetSMART flies from Cali to Santiago around 3 times per week, with 254 momondo users rating the airline 6.6/10. The cheapest JetSMART deal from Cali to Santiago in the last 72 hours was $286 (round-trip), much lower than the average airfare cost of $419 for JetSMART flights on this route.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Cali to Santiago?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Cali to Santiago. momondo saves you time and could save you money on your trip.

Can I find flights from Cali to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Cali to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from Cali to Santiago?

Once all potential Cali to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Cali to Santiago right now. Can momondo alert me if prices change?

Price alerts on flights to Santiago from Cali are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Santiago trip

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