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Cheap flights from Cali to Santiago from $216

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cali to Santiago departing on 3/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Cali to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetSMART Logo
9:53 pm - 12:11 am
CLO
-
SCL
25h 18m
1 stop
JetSMART Logo
3:30 pm - 8:35 pm
SCL
-
CLO
6h 05mnonstop
$326JetSMART
Sun, May 17 - Sun, May 24
JetSMART Logo
9:35 pm - 4:17 am
CLO
-
SCL
5h 42mnonstop
JetSMART Logo
3:30 pm - 8:35 pm
SCL
-
CLO
6h 05mnonstop
$328JetSMART
Sun, Jun 21 - Sun, Jun 28
JetSMART Logo
1:09 pm - 5:44 pm
CLO
-
SCL
26h 35m
1 stop
JetSMART Logo
3:30 pm - 8:35 pm
SCL
-
CLO
6h 05mnonstop
$330JetSMART
Tue, Mar 17 - Wed, Jun 3
JetSMART Logo
9:21 pm - 12:11 am
CLO
-
SCL
25h 50m
2 stops
JetSMART Logo
3:30 pm - 8:35 pm
SCL
-
CLO
6h 05mnonstop
$331JetSMART
Sun, May 17 - Fri, May 22
JetSMART Logo
8:40 pm - 4:22 am
CLO
-
SCL
5h 42mnonstop
JetSMART Logo
3:30 pm - 8:35 pm
SCL
-
CLO
6h 05mnonstop
$334JetSMART
Mon, Mar 16 - Fri, Apr 10
JetSMART Logo
8:35 pm - 4:17 am
CLO
-
SCL
5h 42mnonstop
JetSMART Logo
3:30 pm - 8:35 pm
SCL
-
CLO
6h 05mnonstop
$335JetSMART
Fri, Mar 20 - Fri, Apr 10
JetSMART Logo
8:35 pm - 4:17 am
CLO
-
SCL
5h 42mnonstop
JetSMART Logo
11:48 am - 1:12 pm
SCL
-
CLO
26h 24m
1 stop
$336JetSMART
Wed, Mar 25 - Wed, Apr 8
JetSMART Logo
8:35 pm - 4:17 am
CLO
-
SCL
5h 42mnonstop
JetSMART Logo
3:30 pm - 8:35 pm
SCL
-
CLO
6h 05mnonstop
$337JetSMART
Fri, Mar 27 - Sun, Apr 12
JetSMART Logo
2:15 pm - 12:11 am
CLO
-
SCL
8h 56m
1 stop
JetSMART Logo
3:33 pm - 8:35 pm
SCL
-
CLO
6h 02mnonstop
$338JetSMART
Thu, Jun 4 - Wed, Jul 1
JetSMART Logo
5:11 pm - 12:11 am
CLO
-
SCL
30h 00m
2 stops
JetSMART Logo
3:33 pm - 8:35 pm
SCL
-
CLO
6h 02mnonstop
$339JetSMART
Thu, Jun 4 - Wed, Jul 1

JetSMART flights from Cali to Santiago

Our best JetSMART deals on Cali to Santiago flight tickets
JetSMART
May 17
CLO9:53 pmCali Alfonso B. Aragon Intl
25h 18m
1 stop
SCL12:11 amSantiago Arturo Merino Benitez
May 24
SCL3:30 pmSantiago Arturo Merino Benitez
6h 05m
CLO8:35 pmCali Alfonso B. Aragon Intl
$326
JetSMART
Jun 21
CLO9:35 pmCali Alfonso B. Aragon Intl
5h 42m
SCL4:17 amSantiago Arturo Merino Benitez
Jun 28
SCL3:30 pmSantiago Arturo Merino Benitez
6h 05m
CLO8:35 pmCali Alfonso B. Aragon Intl
$328
JetSMART
Mar 17
CLO1:09 pmCali Alfonso B. Aragon Intl
26h 35m
1 stop
SCL5:44 pmSantiago Arturo Merino Benitez
Jun 3
SCL3:30 pmSantiago Arturo Merino Benitez
6h 05m
CLO8:35 pmCali Alfonso B. Aragon Intl
$330

Copa Airlines flights from Cali to Santiago

Our best Copa Airlines deals on Cali to Santiago flight tickets
Copa Airlines
Feb 5
CLO8:48 amCali Alfonso B. Aragon Intl
17h 26m
1 stop
SCL4:14 amSantiago Arturo Merino Benitez
May 5
SCL4:41 amSantiago Arturo Merino Benitez
10h 29m
1 stop
CLO2:10 pmCali Alfonso B. Aragon Intl
$425
Copa Airlines
Feb 5
CLO12:03 pmCali Alfonso B. Aragon Intl
14h 11m
1 stop
SCL4:14 amSantiago Arturo Merino Benitez
Feb 26
SCL5:20 amSantiago Arturo Merino Benitez
10h 50m
1 stop
CLO2:10 pmCali Alfonso B. Aragon Intl
$461
Copa Airlines
Feb 4
CLO8:48 amCali Alfonso B. Aragon Intl
9h 32m
1 stop
SCL8:20 pmSantiago Arturo Merino Benitez
Apr 22
SCL11:25 amSantiago Arturo Merino Benitez
13h 11m
1 stop
CLO11:36 pmCali Alfonso B. Aragon Intl
$485

momondo Fare Finder

 
Customize your flight search to find flights from Cali to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Cali to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Sun 5/17

9:53 pm-12:11 am

1 stop25h 18m

Santiago Arturo Merino Benitez

Sun 5/24

3:30 pm-8:35 pm

Nonstop6h 05m

$326

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Sun 6/21

9:35 pm-4:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Sun 6/28

3:30 pm-8:35 pm

Nonstop6h 05m

$328

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Tue 3/17

1:09 pm-5:44 pm

1 stop26h 35m

Santiago Arturo Merino Benitez

Wed 6/3

3:30 pm-8:35 pm

Nonstop6h 05m

$330

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Sun 5/17

9:21 pm-12:11 am

2 stops25h 50m

Santiago Arturo Merino Benitez

Fri 5/22

3:30 pm-8:35 pm

Nonstop6h 05m

$331

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Mon 3/16

8:40 pm-4:22 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Fri 4/10

3:30 pm-8:35 pm

Nonstop6h 05m

$334

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Fri 3/20

8:35 pm-4:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Fri 4/10

3:30 pm-8:35 pm

Nonstop6h 05m

$335

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Wed 3/25

8:35 pm-4:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Wed 4/8

11:48 am-1:12 pm

1 stop26h 24m

$336

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Fri 3/27

8:35 pm-4:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Sun 4/12

3:30 pm-8:35 pm

Nonstop6h 05m

$337

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Thu 6/4

2:15 pm-12:11 am

1 stop8h 56m

Santiago Arturo Merino Benitez

Wed 7/1

3:33 pm-8:35 pm

Nonstop6h 02m

$338

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Thu 6/4

5:11 pm-12:11 am

2 stops30h 00m

Santiago Arturo Merino Benitez

Wed 7/1

3:33 pm-8:35 pm

Nonstop6h 02m

$339

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Cali to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, May is the cheapest month to fly from Cali to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $362. If you don’t want to visit Santiago in May, then you should wait until June to fly from Cali, when ticket prices are also cheap, with an average price of $371.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Tuesday when prices can be found for as low as $405. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Monday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Monday is $524.

What is the cheapest time of day to depart on your flight to Santiago?

In the morning is the cheapest time of day to fly from Cali to Santiago when you can find flight prices for as low as $419. Flying to Santiago in the morning is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Santiago, so prices are often more expensive at around $454 per ticket.

What is the cheapest Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez flight route?

Fly from Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez for the best Cali Alfonso B. Aragon Intl - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Cali when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $382 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Cali for as low as $349 on momondo.

What cabin class options are available on Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez flights?

There is only 1 cabin class available to choose from on Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Cali to Santiago flights?

No. A direct flight is the cheapest option for a flight between Cali to Santiago.

How have Cali to Santiago flight prices changed over time?

As of February 2026, prices for Cali to Santiago flights are approximately 18% cheaper when compared to flights at the same time last year.

When to book flights from Cali to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Cali to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Cali to Santiago (CLO to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cali to Santiago

Best Price Found

$389

Fastest flight time

5h 42m

Direct flights

Every day

Airports in Santiago

1 airport
The best one-way flight to Santiago from Cali in the past 72 hours is $389. The best round-trip flight deal from Cali to Santiago found on momondo in the last 72 hours is $538.
The fastest flight from Cali to Santiago takes 5h 42m
Direct flights go from Cali to Santiago every day.
There is 1 airport in Santiago. From Cali there are direct flights to Santiago Arturo Merino Benitez (SCL).
Search flight deals

  • How far is Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez by plane?

    Cali Alfonso B. Aragon Intl and Santiago Arturo Merino Benitez are 2576.4 mi apart from one another. In terms of flight time, this usually takes a little over 5h 42m.

  • When did momondo last update prices for flights from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Cali to Santiago?

  • What is the most popular airline from Cali to Santiago?

Best airlines flying from Cali to Santiago

Compare and see reviews for airlines that fly from Cali to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $227Free CancellationRating
6.5
2,498 reviews
Search Avianca flights
JetSMARTPriceFrom $266Free CancellationRating
6.7
266 reviews
Search JetSMART flights

  • JetSMART Flights From Cali to Santiago

    JetSMART flies from Cali to Santiago around 5 times per week, with 266 momondo users rating the airline 6.7/10. The cheapest JetSMART deal from Cali to Santiago in the last 72 hours was $266 (round-trip), much lower than the average airfare cost of $409 for JetSMART flights on this route.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Cali to Santiago?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Cali to Santiago. momondo saves you time and could save you money on your trip.

Can I find flights from Cali to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Cali to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from Cali to Santiago?

Once all potential Cali to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Cali to Santiago right now. Can momondo alert me if prices change?

Price alerts on flights to Santiago from Cali are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Santiago trip

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