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Cheap flights from Cali to Santiago from $191

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cali to Santiago departing on 10/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

JetSMART Logo
8:35 pm - 4:17 amCLO-SCL
5h 42mnonstop
JetSMART Logo
5:04 pm - 9:02 pmSCL-CLO
5h 58mnonstop
$332JetSMART
Find Deal
lun., dic. 15 - dom., ene. 18
JetSMART Logo
1:09 pm - 7:55 pmCLO-SCL
28h 46m1 stop
JetSMART Logo
5:04 pm - 9:02 pmSCL-CLO
5h 58mnonstop
$343JetSMART
Find Deal
lun., dic. 15 - dom., ene. 18
Avianca Logo
6:18 pm - 5:15 amCLO-SCL
8h 57m1 stop
Avianca Logo
3:30 pm - 11:18 pmSCL-CLO
9h 48m1 stop
$375Avianca
Find Deal
lun., oct. 6 - mié., oct. 15
Copa Airlines Logo
4:52 am - 8:21 pmCLO-SCL
13h 29m1 stop
Copa Airlines Logo
3:23 am - 11:01 amSCL-CLO
9h 38m1 stop
$376Copa Airlines
Find Deal
mar., nov. 18 - jue., nov. 27
LATAM Airlines Logo
6:05 pm - 2:45 pmCLO-SCL
18h 40m1 stop
LATAM Airlines Logo
4:35 pm - 3:51 pmSCL-CLO
25h 16m2 stops
$379LATAM Airlines
Find Deal
lun., oct. 6 - mié., oct. 15
LATAM Airlines Logo
9:42 pm - 2:20 pmCLO-SCL
14h 38m1 stop
LATAM Airlines Logo
4:35 pm - 6:26 amSCL-CLO
15h 51m1 stop
$381LATAM Airlines
Find Deal
sáb., oct. 25 - jue., oct. 30
Copa Airlines Logo
12:04 pm - 11:41 pmCLO-SCL
9h 37m1 stop
Copa Airlines Logo
5:20 am - 2:10 pmSCL-CLO
10h 50m1 stop
$392Copa Airlines
Find Deal
mar., dic. 23 - lun., feb. 9
Multiple Airlines Logo
4:05 pm - 5:30 amCLO-SCL
11h 25m1 stop
Multiple Airlines Logo
3:33 pm - 7:31 pmSCL-CLO
5h 58mnonstop
$393Multiple Airlines
Find Deal
jue., oct. 30 - jue., nov. 6
Multiple Airlines Logo
8:35 pm - 4:17 amCLO-SCL
5h 42mnonstop
Multiple Airlines Logo
4:25 pm - 11:40 pmSCL-CLO
9h 15m1 stop
$405Multiple Airlines
Find Deal
dom., oct. 26 - jue., oct. 30
Avianca Logo
12:42 pm - 11:30 pmCLO-SCL
8h 48m1 stop
Avianca Logo
12:55 am - 10:04 amSCL-CLO
11h 09m1 stop
$418Avianca
Find Deal
mié., oct. 8 - dom., oct. 12

Avianca flights from Cali to Santiago

Our best Avianca deals on Cali to Santiago flight tickets
Avianca
Oct 6
CLO6:18 pmCali Alfonso B. Aragon Intl
8h 57m
1 stop
SCL5:15 amSantiago Arturo Merino Benitez
Oct 15
SCL3:30 pmSantiago Arturo Merino Benitez
9h 48m
1 stop
CLO11:18 pmCali Alfonso B. Aragon Intl
$375
Find similar
Avianca
Oct 8
CLO12:42 pmCali Alfonso B. Aragon Intl
8h 48m
1 stop
SCL11:30 pmSantiago Arturo Merino Benitez
Oct 12
SCL12:55 amSantiago Arturo Merino Benitez
11h 09m
1 stop
CLO10:04 amCali Alfonso B. Aragon Intl
$418
Find similar
Avianca
Sep 22
CLO7:24 pmCali Alfonso B. Aragon Intl
7h 51m
1 stop
SCL5:15 amSantiago Arturo Merino Benitez
Sep 28
SCL12:55 amSantiago Arturo Merino Benitez
8h 40m
1 stop
CLO7:35 amCali Alfonso B. Aragon Intl
$687
Find similar

LATAM Airlines flights from Cali to Santiago

Our best LATAM Airlines deals on Cali to Santiago flight tickets
LATAM Airlines
Oct 6
CLO6:05 pmCali Alfonso B. Aragon Intl
18h 40m
1 stop
SCL2:45 pmSantiago Arturo Merino Benitez
Oct 15
SCL4:35 pmSantiago Arturo Merino Benitez
25h 16m
2 stops
CLO3:51 pmCali Alfonso B. Aragon Intl
$379
Find similar
LATAM Airlines
Oct 25
CLO9:42 pmCali Alfonso B. Aragon Intl
14h 38m
1 stop
SCL2:20 pmSantiago Arturo Merino Benitez
Oct 30
SCL4:35 pmSantiago Arturo Merino Benitez
15h 51m
1 stop
CLO6:26 amCali Alfonso B. Aragon Intl
$381
Find similar
LATAM Airlines
Oct 15
CLO6:25 amCali Alfonso B. Aragon Intl
21h 20m
2 stops
SCL5:45 amSantiago Arturo Merino Benitez
Oct 21
SCL12:10 amSantiago Arturo Merino Benitez
14h 49m
1 stop
CLO12:59 pmCali Alfonso B. Aragon Intl
$389
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Cali to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated septiembre 16, 2025.
Use the filters below to find and compare flights from Cali to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

lun. 12/15

8:35 pm-4:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

dom. 1/18

5:04 pm-9:02 pm

Nonstop5h 58m

$332

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

lun. 12/15

1:09 pm-7:55 pm

1 stop28h 46m

Santiago Arturo Merino Benitez

dom. 1/18

5:04 pm-9:02 pm

Nonstop5h 58m

$343

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

lun. 10/6

6:18 pm-5:15 am

1 stop8h 57m

Santiago Arturo Merino Benitez

mié. 10/15

3:30 pm-11:18 pm

1 stop9h 48m

$375

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

mar. 11/18

4:52 am-8:21 pm

1 stop13h 29m

Santiago Arturo Merino Benitez

jue. 11/27

3:23 am-11:01 am

1 stop9h 38m

$376

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

lun. 10/6

6:05 pm-2:45 pm

1 stop18h 40m

Santiago Arturo Merino Benitez

mié. 10/15

4:35 pm-3:51 pm

2 stops25h 16m

$379

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

sáb. 10/25

9:42 pm-2:20 pm

1 stop14h 38m

Santiago Arturo Merino Benitez

jue. 10/30

4:35 pm-6:26 am

1 stop15h 51m

$381

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

mar. 12/23

12:04 pm-11:41 pm

1 stop9h 37m

Santiago Arturo Merino Benitez

lun. 2/9

5:20 am-2:10 pm

1 stop10h 50m

$392

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

jue. 10/30

4:05 pm-5:30 am

1 stop11h 25m

Santiago Arturo Merino Benitez

jue. 11/6

3:33 pm-7:31 pm

Nonstop5h 58m

$393

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

dom. 10/26

8:35 pm-4:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

jue. 10/30

4:25 pm-11:40 pm

1 stop9h 15m

$405

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

mié. 10/8

12:42 pm-11:30 pm

1 stop8h 48m

Santiago Arturo Merino Benitez

dom. 10/12

12:55 am-10:04 am

1 stop11h 09m

$418

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Cali to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Cali and Santiago?

What is the cheapest month to fly to Santiago?

In general, October is the cheapest month to fly from Cali to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $335. If you don’t want to visit Santiago in October, then you should wait until May to fly from Cali, when ticket prices are also cheap, with an average price of $363.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $422. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Wednesday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Wednesday is $535.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from Cali to Santiago when you can find flight prices for as low as $262. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Santiago, so prices are often more expensive at around $481 per ticket.

What is the cheapest Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez flight route?

Fly from Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez for the best Cali Alfonso B. Aragon Intl - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Cali when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $377 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Cali for as low as $344 on momondo.

What cabin class options are available on Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez flights?

There is only 1 cabin class available to choose from on Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Cali to Santiago flights?

You could potentially save up to 31% on your flight if you consider stops on a Cali to Santiago flight.

How have Cali to Santiago flight prices changed over time?

As of September 2025, prices for Cali to Santiago flights are approximately 13% more expensive when compared to flights at the same time last year.

When to book flights from Cali to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Cali to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Cali to Santiago (CLO to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cali to Santiago

Best Price Found

$456

Fastest flight time

5h 42m

Direct flights

Every day

Airports in Santiago

1 airport
The best one-way flight to Santiago from Cali in the past 72 hours is $456. The best round-trip flight deal from Cali to Santiago found on momondo in the last 72 hours is $325.
The fastest flight from Cali to Santiago takes 5h 42m
Direct flights go from Cali to Santiago every day.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)
Search flight deals

  • How far is Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez by plane?

    Cali Alfonso B. Aragon Intl and Santiago Arturo Merino Benitez are 2576.4 mi apart from one another. In terms of flight time, this usually takes a little over 5h 42m.

  • When did momondo last update prices for flights from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Cali to Santiago?

  • What is the most popular airline from Cali to Santiago?

Best airlines flying from Cali to Santiago

Compare and see reviews for airlines that fly from Cali to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $230Free CancellationRating
6.7
2,435 reviews
Search Avianca flights
JetSMARTPriceFrom $266Free CancellationRating
6.5
225 reviews
Search JetSMART flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Cali to Santiago?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Cali to Santiago. momondo saves you time and could save you money on your trip.

Can I find flights from Cali to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Cali to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from Cali to Santiago?

Once all potential Cali to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Cali to Santiago right now. Can momondo alert me if prices change?

Price alerts on flights to Santiago from Cali are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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