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Cheap flights from Cali to Santiago from $214

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cali to Santiago departing on 12/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Cali to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetSMART Logo
8:35 pm - 4:17 amCLO-SCL
5h 42mnonstop
JetSMART Logo
8:13 pm - 7:08 amSCL-CLO
12h 55m1 stop
$346JetSMART
Find Deal
Wed, Nov 26 - Fri, Feb 6
JetSMART Logo
9:00 pm - 4:42 amCLO-SCL
5h 42mnonstop
JetSMART Logo
8:13 pm - 10:03 pmSCL-CLO
27h 50m1 stop
$347JetSMART
Find Deal
Tue, Dec 23 - Mon, Feb 9
JetSMART Logo
9:35 pm - 5:17 amCLO-SCL
5h 42mnonstop
JetSMART Logo
3:33 pm - 8:35 pmSCL-CLO
6h 02mnonstop
$351JetSMART
Find Deal
Wed, Mar 18 - Sun, Apr 5
JetSMART Logo
8:35 pm - 4:17 amCLO-SCL
5h 42mnonstop
JetSMART Logo
4:33 pm - 8:35 pmSCL-CLO
6h 02mnonstop
$352JetSMART
Find Deal
Wed, Dec 3 - Sun, Mar 1
JetSMART Logo
9:35 pm - 5:17 amCLO-SCL
5h 42mnonstop
JetSMART Logo
4:33 pm - 8:35 pmSCL-CLO
6h 02mnonstop
$353JetSMART
Find Deal
Wed, Mar 11 - Wed, Mar 18
Multiple Airlines Logo
9:35 pm - 5:17 amCLO-SCL
5h 42mnonstop
Multiple Airlines Logo
7:25 am - 2:45 pmSCL-CLO
9h 20m1 stop
$367Multiple Airlines
Find Deal
Fri, Mar 13 - Sun, Mar 22
Avianca Logo
5:20 pm - 5:30 amCLO-SCL
10h 10m1 stop
Avianca Logo
7:25 am - 2:45 pmSCL-CLO
9h 20m1 stop
$371Avianca
Find Deal
Sat, Mar 14 - Sun, Mar 22
LATAM Airlines Logo
9:41 pm - 2:00 pmCLO-SCL
15h 19m2 stops
LATAM Airlines Logo
7:45 am - 7:04 pmSCL-CLO
12h 19m2 stops
$379LATAM Airlines
Find Deal
Tue, Apr 21 - Thu, May 7
LATAM Airlines Logo
7:55 pm - 2:30 pmCLO-SCL
16h 35m1 stop
LATAM Airlines Logo
12:25 am - 8:26 amSCL-CLO
10h 01m1 stop
$406LATAM Airlines
Find Deal
Fri, Mar 13 - Sat, Mar 21
Multiple Airlines Logo
5:07 am - 10:39 amCLO-SCL
27h 32m3 stops
Multiple Airlines Logo
10:25 pm - 5:30 pmSCL-CLO
21h 05m2 stops
$412Multiple Airlines
Find Deal
Fri, Mar 13 - Sun, Mar 22

JetSMART flights from Cali to Santiago

Our best JetSMART deals on Cali to Santiago flight tickets
JetSMART
Nov 26
CLO8:35 pmCali Alfonso B. Aragon Intl
5h 42m
SCL4:17 amSantiago Arturo Merino Benitez
Feb 6
SCL8:13 pmSantiago Arturo Merino Benitez
12h 55m
1 stop
CLO7:08 amCali Alfonso B. Aragon Intl
$346
Find similar
JetSMART
Dec 23
CLO9:00 pmCali Alfonso B. Aragon Intl
5h 42m
SCL4:42 amSantiago Arturo Merino Benitez
Feb 9
SCL8:13 pmSantiago Arturo Merino Benitez
27h 50m
1 stop
CLO10:03 pmCali Alfonso B. Aragon Intl
$347
Find similar
JetSMART
Mar 18
CLO9:35 pmCali Alfonso B. Aragon Intl
5h 42m
SCL5:17 amSantiago Arturo Merino Benitez
Apr 5
SCL3:33 pmSantiago Arturo Merino Benitez
6h 02m
CLO8:35 pmCali Alfonso B. Aragon Intl
$351
Find similar

LATAM Airlines flights from Cali to Santiago

Our best LATAM Airlines deals on Cali to Santiago flight tickets
LATAM Airlines
Apr 21
CLO9:41 pmCali Alfonso B. Aragon Intl
15h 19m
2 stops
SCL2:00 pmSantiago Arturo Merino Benitez
May 7
SCL7:45 amSantiago Arturo Merino Benitez
12h 19m
2 stops
CLO7:04 pmCali Alfonso B. Aragon Intl
$379
Find similar
LATAM Airlines
Mar 13
CLO7:55 pmCali Alfonso B. Aragon Intl
16h 35m
1 stop
SCL2:30 pmSantiago Arturo Merino Benitez
Mar 21
SCL12:25 amSantiago Arturo Merino Benitez
10h 01m
1 stop
CLO8:26 amCali Alfonso B. Aragon Intl
$406
Find similar
LATAM Airlines
Dec 15
CLO10:50 pmCali Alfonso B. Aragon Intl
13h 30m
1 stop
SCL2:20 pmSantiago Arturo Merino Benitez
Jan 18
SCL8:50 pmSantiago Arturo Merino Benitez
10h 52m
2 stops
CLO5:42 amCali Alfonso B. Aragon Intl
$407
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Cali to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 31, 2025.
Use the filters below to find and compare flights from Cali to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Wed 11/26

8:35 pm-4:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Fri 2/6

8:13 pm-7:08 am

1 stop12h 55m

$346

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Tue 12/23

9:00 pm-4:42 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Mon 2/9

8:13 pm-10:03 pm

1 stop27h 50m

$347

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Wed 3/18

9:35 pm-5:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Sun 4/5

3:33 pm-8:35 pm

Nonstop6h 02m

$351

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Wed 12/3

8:35 pm-4:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Sun 3/1

4:33 pm-8:35 pm

Nonstop6h 02m

$352

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Wed 3/11

9:35 pm-5:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Wed 3/18

4:33 pm-8:35 pm

Nonstop6h 02m

$353

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Fri 3/13

9:35 pm-5:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Sun 3/22

7:25 am-2:45 pm

1 stop9h 20m

$367

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Sat 3/14

5:20 pm-5:30 am

1 stop10h 10m

Santiago Arturo Merino Benitez

Sun 3/22

7:25 am-2:45 pm

1 stop9h 20m

$371

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Tue 4/21

9:41 pm-2:00 pm

2 stops15h 19m

Santiago Arturo Merino Benitez

Thu 5/7

7:45 am-7:04 pm

2 stops12h 19m

$379

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Fri 3/13

7:55 pm-2:30 pm

1 stop16h 35m

Santiago Arturo Merino Benitez

Sat 3/21

12:25 am-8:26 am

1 stop10h 01m

$406

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Fri 3/13

5:07 am-10:39 am

3 stops27h 32m

Santiago Arturo Merino Benitez

Sun 3/22

10:25 pm-5:30 pm

2 stops21h 05m

$412

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Cali to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Cali and Santiago?

What is the cheapest month to fly to Santiago?

In general, May is the cheapest month to fly from Cali to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $363. If you don’t want to visit Santiago in May, then you should wait until December to fly from Cali, when ticket prices are also cheap, with an average price of $363.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $422. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Wednesday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Wednesday is $535.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from Cali to Santiago when you can find flight prices for as low as $262. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Santiago, so prices are often more expensive at around $486 per ticket.

What is the cheapest Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez flight route?

Fly from Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez for the best Cali Alfonso B. Aragon Intl - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Cali when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $379 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Cali for as low as $342 on momondo.

What cabin class options are available on Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez flights?

There is only 1 cabin class available to choose from on Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Cali to Santiago flights?

No. A direct flight is the cheapest option for a flight between Cali to Santiago.

How have Cali to Santiago flight prices changed over time?

As of October 2025, prices for Cali to Santiago flights are approximately 12% more expensive when compared to flights at the same time last year.

When to book flights from Cali to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Cali to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Cali to Santiago (CLO to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cali to Santiago

Best Price Found

$179

Fastest flight time

5h 42m

Direct flights

Every day

Airports in Santiago

1 airport
The best one-way flight to Santiago from Cali in the past 72 hours is $179. The best round-trip flight deal from Cali to Santiago found on momondo in the last 72 hours is $308.
The fastest flight from Cali to Santiago takes 5h 42m
Direct flights go from Cali to Santiago every day.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)
Search flight deals

  • How far is Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez by plane?

    Cali Alfonso B. Aragon Intl and Santiago Arturo Merino Benitez are 2576.4 mi apart from one another. In terms of flight time, this usually takes a little over 5h 42m.

  • When did momondo last update prices for flights from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Cali Alfonso B. Aragon Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Cali to Santiago?

  • What is the most popular airline from Cali to Santiago?

Best airlines flying from Cali to Santiago

Compare and see reviews for airlines that fly from Cali to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $230Free CancellationRating
6.6
2,468 reviews
Search Avianca flights
JetSMARTPriceFrom $266Free CancellationRating
6.6
236 reviews
Search JetSMART flights

  • JetSMART Flights From Cali to Santiago

    JetSMART flies from Cali to Santiago around 1 time per week, with 236 momondo users rating the airline 6.6/10. The cheapest JetSMART deal from Cali to Santiago in the last 72 hours was $266 (round-trip), much lower than the average airfare cost of $437 for JetSMART flights on this route.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Cali to Santiago?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Cali to Santiago. momondo saves you time and could save you money on your trip.

Can I find flights from Cali to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Cali to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from Cali to Santiago?

Once all potential Cali to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Cali to Santiago right now. Can momondo alert me if prices change?

Price alerts on flights to Santiago from Cali are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Santiago trip

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