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Cheap flights from Buffalo to Santo Domingo from $215

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Santo Domingo departing on 8/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Buffalo to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
7:00 am - 6:01 pm
BUF
-
SDQ
11h 01m
1 stop
Delta Logo
6:05 am - 7:15 pm
SDQ
-
BUF
13h 10m
1 stop
$380Delta
Wed, Jun 3 - Sat, Jun 6
Delta Logo
7:00 am - 6:01 pm
BUF
-
SDQ
11h 01m
1 stop
Delta Logo
6:06 am - 3:17 pm
SDQ
-
BUF
9h 11m
1 stop
$386Delta
Sat, Jun 6 - Sat, Jun 13
American Airlines Logo
6:45 am - 1:00 pm
BUF
-
SDQ
6h 15m
1 stop
American Airlines Logo
5:25 pm - 10:43 am
SDQ
-
BUF
17h 18m
2 stops
$431American Airlines
Sun, Sep 6 - Fri, Sep 11
Delta Logo
10:00 am - 12:42 am
BUF
-
SDQ
14h 42m
1 stop
Delta Logo
6:06 am - 3:09 pm
SDQ
-
BUF
9h 03m
1 stop
$435Delta
Mon, Jun 8 - Mon, Jun 15
United Airlines Logo
6:00 am - 11:46 pm
BUF
-
SDQ
16h 46m
1 stop
United Airlines Logo
2:53 pm - 10:37 pm
SDQ
-
BUF
8h 44m
1 stop
$446United Airlines
Sun, Nov 8 - Wed, Nov 11
United Airlines Logo
6:00 am - 11:46 pm
BUF
-
SDQ
16h 46m
1 stop
United Airlines Logo
2:53 pm - 9:47 am
SDQ
-
BUF
19h 54m
2 stops
$451United Airlines
Sun, Nov 8 - Wed, Nov 11
American Airlines Logo
12:51 pm - 10:55 pm
BUF
-
SDQ
10h 04m
2 stops
American Airlines Logo
7:35 pm - 12:47 pm
SDQ
-
BUF
17h 12m
2 stops
$460American Airlines
Wed, Jun 3 - Sat, Jun 6
American Airlines Logo
7:56 pm - 12:20 pm
BUF
-
SDQ
16h 24m
2 stops
American Airlines Logo
2:00 pm - 11:56 pm
SDQ
-
BUF
9h 56m
1 stop
$465American Airlines
Thu, Oct 15 - Tue, Oct 20
Delta Logo
3:49 pm - 12:42 am
BUF
-
SDQ
8h 53m
1 stop
Delta Logo
2:05 pm - 12:38 am
SDQ
-
BUF
10h 33m
1 stop
$482Delta
Mon, Jun 8 - Mon, Jun 15
American Airlines Logo
6:00 am - 6:35 pm
BUF
-
SDQ
12h 35m
2 stops
American Airlines Logo
4:24 pm - 12:06 pm
SDQ
-
BUF
19h 42m
2 stops
$485American Airlines
Wed, Jul 1 - Tue, Sep 1

Delta flights from Buffalo to Santo Domingo

Our best Delta deals on Buffalo to Santo Domingo flight tickets
Delta
Jun 3
BUF7:00 amBuffalo
11h 01m
1 stop
SDQ6:01 pmSanto Domingo Las Americas
Jun 6
SDQ6:05 amSanto Domingo Las Americas
13h 10m
1 stop
BUF7:15 pmBuffalo
$380
Delta
Jun 6
BUF7:00 amBuffalo
11h 01m
1 stop
SDQ6:01 pmSanto Domingo Las Americas
Jun 13
SDQ6:06 amSanto Domingo Las Americas
9h 11m
1 stop
BUF3:17 pmBuffalo
$386
Delta
Jun 8
BUF10:00 amBuffalo
14h 42m
1 stop
SDQ12:42 amSanto Domingo Las Americas
Jun 15
SDQ6:06 amSanto Domingo Las Americas
9h 03m
1 stop
BUF3:09 pmBuffalo
$435

American Airlines flights from Buffalo to Santo Domingo

Our best American Airlines deals on Buffalo to Santo Domingo flight tickets
American Airlines
Sep 6
BUF6:45 amBuffalo
6h 15m
1 stop
SDQ1:00 pmSanto Domingo Las Americas
Sep 11
SDQ5:25 pmSanto Domingo Las Americas
17h 18m
2 stops
BUF10:43 amBuffalo
$431
American Airlines
Jun 3
BUF12:51 pmBuffalo
10h 04m
2 stops
SDQ10:55 pmSanto Domingo Las Americas
Jun 6
SDQ7:35 pmSanto Domingo Las Americas
17h 12m
2 stops
BUF12:47 pmBuffalo
$460
American Airlines
Oct 15
BUF7:56 pmBuffalo
16h 24m
2 stops
SDQ12:20 pmSanto Domingo Las Americas
Oct 20
SDQ2:00 pmSanto Domingo Las Americas
9h 56m
1 stop
BUF11:56 pmBuffalo
$465

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from Buffalo to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 6/3

7:00 am-6:01 pm

1 stop11h 01m

Santo Domingo Las Americas

Sat 6/6

6:05 am-7:15 pm

1 stop13h 10m

$380

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sat 6/6

7:00 am-6:01 pm

1 stop11h 01m

Santo Domingo Las Americas

Sat 6/13

6:06 am-3:17 pm

1 stop9h 11m

$386

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 9/6

6:45 am-1:00 pm

1 stop6h 15m

Santo Domingo Las Americas

Fri 9/11

5:25 pm-10:43 am

2 stops17h 18m

$431

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Mon 6/8

10:00 am-12:42 am

1 stop14h 42m

Santo Domingo Las Americas

Mon 6/15

6:06 am-3:09 pm

1 stop9h 03m

$435

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 11/8

6:00 am-11:46 pm

1 stop16h 46m

Santo Domingo Las Americas

Wed 11/11

2:53 pm-10:37 pm

1 stop8h 44m

$446

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 11/8

6:00 am-11:46 pm

1 stop16h 46m

Santo Domingo Las Americas

Wed 11/11

2:53 pm-9:47 am

2 stops19h 54m

$451

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 6/3

12:51 pm-10:55 pm

2 stops10h 04m

Santo Domingo Las Americas

Sat 6/6

7:35 pm-12:47 pm

2 stops17h 12m

$460

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Thu 10/15

7:56 pm-12:20 pm

2 stops16h 24m

Santo Domingo Las Americas

Tue 10/20

2:00 pm-11:56 pm

1 stop9h 56m

$465
Quickest round-trip

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Mon 6/8

3:49 pm-12:42 am

1 stop8h 53m

Santo Domingo Las Americas

Mon 6/15

2:05 pm-12:38 am

1 stop10h 33m

$482

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 7/1

6:00 am-6:35 pm

2 stops12h 35m

Santo Domingo Las Americas

Tue 9/1

4:24 pm-12:06 pm

2 stops19h 42m

$485

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Buffalo to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Buffalo and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in February, then you should wait until January to fly from Buffalo, when ticket prices are also cheap, with an average price of $361.

Can stopping save me money on Buffalo to Santo Domingo flights?

You could potentially save up to 19% on your flight if you consider stops on a Buffalo to Santo Domingo flight.

When to book flights from Buffalo to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to Santo Domingo (BUF to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Santo Domingo

Fastest flight time

11h 01m

Direct flights

None
The fastest flight from Buffalo to Santo Domingo takes 11h 01m
There are no direct flights from Buffalo to Santo Domingo. There are no popular flight routes from Buffalo to Santo Domingo.
Search flight deals

Frequently asked questions about flying from Buffalo to Santo Domingo

  • How far is Buffalo to Santo Domingo Las Americas by plane?

    Santo Domingo Las Americas is 1764.1 mi away from Buffalo. By plane, this route typically takes 11h 01m.

  • When did momondo last update prices for flights from Buffalo Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Buffalo Airport to Santo Domingo Las Americas Airport are updated daily.

  • How many operators does momondo search for flights from Buffalo Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Buffalo Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Buffalo to Santo Domingo?

Best airlines flying from Buffalo to Santo Domingo

Compare and see reviews for airlines that fly from Buffalo to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $181Free CancellationRating
7.9
8,452 reviews
Search Delta flights
JetBluePriceFrom $325Free CancellationRating
7.1
2,971 reviews
Search JetBlue flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Santo Domingo?

Finding the right flight to Santo Domingo from Buffalo is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santo Domingo quick and easy, saving you time and money.

Can I find flights from Buffalo to Santo Domingo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santo Domingo from Buffalo with this policy.

How can momondo help me find flights from Buffalo to Santo Domingo?

momondo provides multiple filters to help you find the best flight to Santo Domingo from Buffalo. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Buffalo to Santo Domingo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Buffalo to Santo Domingo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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