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Cheap flights from Buffalo to Santo Domingo from $150

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Santo Domingo departing on 11/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Buffalo to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:35 pm - 12:28 pmBUF-SDQ
16h 53m2 stops
American Airlines Logo
1:28 pm - 10:51 pmSDQ-BUF
10h 23m2 stops
$328American Airlines
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Wed, Dec 3 - Wed, Dec 10
American Airlines Logo
6:53 pm - 2:00 pmBUF-SDQ
18h 07m2 stops
American Airlines Logo
3:00 pm - 11:41 pmSDQ-BUF
9h 41m2 stops
$332American Airlines
Find Deal
Thu, Jan 15 - Thu, Jan 22
Delta Logo
11:51 am - 11:59 pmBUF-SDQ
11h 08m1 stop
Delta Logo
8:00 pm - 11:11 amSDQ-BUF
16h 11m1 stop
$342Delta
Find Deal
Sun, Mar 1 - Thu, Mar 5
JetBlue Logo
12:18 pm - 12:24 amBUF-SDQ
11h 06m1 stop
JetBlue Logo
3:28 pm - 10:12 pmSDQ-BUF
7h 44m1 stop
$374JetBlue
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Wed, Dec 3 - Wed, Dec 10
JetBlue Logo
9:20 pm - 9:03 amBUF-SDQ
11h 43m1 stop
JetBlue Logo
4:05 am - 2:25 pmSDQ-BUF
10h 20m1 stop
$388JetBlue
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Sat, Mar 28 - Tue, Apr 7
Multiple Airlines Logo
12:37 pm - 11:51 amBUF-SDQ
22h 14m2 stops
Multiple Airlines Logo
2:53 pm - 12:52 pmSDQ-BUF
22h 59m1 stop
$393Multiple Airlines
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Fri, Dec 12 - Mon, Dec 22
Delta Logo
11:51 am - 12:32 amBUF-SDQ
11h 41m1 stop
Delta Logo
7:31 am - 7:03 pmSDQ-BUF
12h 32m1 stop
$398Delta
Find Deal
Sat, Jan 17 - Fri, Jan 23
JetBlue Logo
7:05 am - 12:24 amBUF-SDQ
16h 19m1 stop
JetBlue Logo
4:10 am - 3:59 pmSDQ-BUF
12h 49m1 stop
$406JetBlue
Find Deal
Wed, Dec 3 - Tue, Dec 9
United Airlines Logo
6:00 am - 1:41 pmBUF-SDQ
6h 41m1 stop
United Airlines Logo
6:00 am - 4:53 pmSDQ-BUF
11h 53m2 stops
$541United Airlines
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Wed, Dec 3 - Wed, Dec 10
United Airlines Logo
6:00 am - 1:41 pmBUF-SDQ
6h 41m1 stop
United Airlines Logo
2:53 pm - 11:46 pmSDQ-BUF
9h 53m2 stops
$552United Airlines
Find Deal
Sun, Mar 1 - Thu, Mar 5

Delta flights from Buffalo to Santo Domingo

Our best Delta deals on Buffalo to Santo Domingo flight tickets
Delta
Mar 1
BUF11:51 amBuffalo
11h 08m
1 stop
SDQ11:59 pmSanto Domingo Las Americas
Mar 5
SDQ8:00 pmSanto Domingo Las Americas
16h 11m
1 stop
BUF11:11 amBuffalo
$342
Find similar
Delta
Jan 17
BUF11:51 amBuffalo
11h 41m
1 stop
SDQ12:32 amSanto Domingo Las Americas
Jan 23
SDQ7:31 amSanto Domingo Las Americas
12h 32m
1 stop
BUF7:03 pmBuffalo
$398
Find similar
Delta
Jan 15
BUF11:51 amBuffalo
6h 23m
1 stop
SDQ7:14 pmSanto Domingo Las Americas
Jan 22
SDQ7:31 amSanto Domingo Las Americas
17h 45m
1 stop
BUF12:16 amBuffalo
$423
Find similar

American Airlines flights from Buffalo to Santo Domingo

Our best American Airlines deals on Buffalo to Santo Domingo flight tickets
American Airlines
Dec 3
BUF6:35 pmBuffalo
16h 53m
2 stops
SDQ12:28 pmSanto Domingo Las Americas
Dec 10
SDQ1:28 pmSanto Domingo Las Americas
10h 23m
2 stops
BUF10:51 pmBuffalo
$328
Find similar
American Airlines
Jan 15
BUF6:53 pmBuffalo
18h 07m
2 stops
SDQ2:00 pmSanto Domingo Las Americas
Jan 22
SDQ3:00 pmSanto Domingo Las Americas
9h 41m
2 stops
BUF11:41 pmBuffalo
$332
Find similar
American Airlines
Dec 8
BUF5:05 amBuffalo
17h 45m
2 stops
SDQ11:50 pmSanto Domingo Las Americas
Dec 10
SDQ3:06 pmSanto Domingo Las Americas
9h 38m
2 stops
BUF11:44 pmBuffalo
$435
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momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Buffalo to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 12/3

6:35 pm-12:28 pm

2 stops16h 53m

Santo Domingo Las Americas

Wed 12/10

1:28 pm-10:51 pm

2 stops10h 23m

$328

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Thu 1/15

6:53 pm-2:00 pm

2 stops18h 07m

Santo Domingo Las Americas

Thu 1/22

3:00 pm-11:41 pm

2 stops9h 41m

$332

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 3/1

11:51 am-11:59 pm

1 stop11h 08m

Santo Domingo Las Americas

Thu 3/5

8:00 pm-11:11 am

1 stop16h 11m

$342

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 12/3

12:18 pm-12:24 am

1 stop11h 06m

Santo Domingo Las Americas

Wed 12/10

3:28 pm-10:12 pm

1 stop7h 44m

$374

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sat 3/28

9:20 pm-9:03 am

1 stop11h 43m

Santo Domingo Las Americas

Tue 4/7

4:05 am-2:25 pm

1 stop10h 20m

$388

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Fri 12/12

12:37 pm-11:51 am

2 stops22h 14m

Santo Domingo Las Americas

Mon 12/22

2:53 pm-12:52 pm

1 stop22h 59m

$393

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sat 1/17

11:51 am-12:32 am

1 stop11h 41m

Santo Domingo Las Americas

Fri 1/23

7:31 am-7:03 pm

1 stop12h 32m

$398

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 12/3

7:05 am-12:24 am

1 stop16h 19m

Santo Domingo Las Americas

Tue 12/9

4:10 am-3:59 pm

1 stop12h 49m

$406

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 12/3

6:00 am-1:41 pm

1 stop6h 41m

Santo Domingo Las Americas

Wed 12/10

6:00 am-4:53 pm

2 stops11h 53m

$541

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 3/1

6:00 am-1:41 pm

1 stop6h 41m

Santo Domingo Las Americas

Thu 3/5

2:53 pm-11:46 pm

2 stops9h 53m

$552

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Buffalo to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Buffalo and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in September, then you should wait until March to fly from Buffalo, when ticket prices are also cheap, with an average price of $438.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Tuesday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $409. The most expensive day to fly to Santo Domingo is Sunday, with ticket prices averaging around $728.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the evening when flights can be purchased for as low as $465. Try not to purchase tickets in the morning because they tend to be around $567. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Buffalo to Santo Domingo flights?

You could potentially save up to 19% on your flight if you consider stops on a Buffalo to Santo Domingo flight.

When to book flights from Buffalo to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to Santo Domingo (BUF to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Santo Domingo

Direct flights

None
There are no direct flights from Buffalo to Santo Domingo. There are no popular flight routes from Buffalo to Santo Domingo.
Search flight deals

  • How far is Buffalo to Santo Domingo Las Americas by plane?

    Santo Domingo Las Americas is 1764.1 mi away from Buffalo. By plane, this route typically takes 6h 23m.

  • When did momondo last update prices for flights from Buffalo Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Buffalo Airport to Santo Domingo Las Americas Airport are updated daily.

  • How many operators does momondo search for flights from Buffalo Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Buffalo Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Buffalo to Santo Domingo?

Best airlines flying from Buffalo to Santo Domingo

Compare and see reviews for airlines that fly from Buffalo to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $422Free CancellationRating
7.9
8,004 reviews
Search Delta flights
JetBluePriceFrom $422Free CancellationRating
7.2
2,907 reviews
Search JetBlue flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Santo Domingo?

Finding the right flight to Santo Domingo from Buffalo is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santo Domingo quick and easy, saving you time and money.

Can I find flights from Buffalo to Santo Domingo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santo Domingo from Buffalo with this policy.

How can momondo help me find flights from Buffalo to Santo Domingo?

momondo provides multiple filters to help you find the best flight to Santo Domingo from Buffalo. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Buffalo to Santo Domingo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Buffalo to Santo Domingo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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