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Cheap flights from Buffalo to Santo Domingo from $200

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Santo Domingo departing on 10/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Buffalo to Santo Domingo (BUF-SDQ)

Cheap round-trip flights

JetBlue Logo
9:38 am - 4:55 pmBUF-SDQ
7h 17m1 stop
JetBlue Logo
2:30 pm - 10:27 pmSDQ-BUF
7h 57m1 stop
$384JetBlue
Find Deal
Wed, Oct 22 - Wed, Oct 29
JetBlue Logo
3:55 pm - 11:37 pmBUF-SDQ
7h 42m1 stop
JetBlue Logo
3:12 am - 3:39 pmSDQ-BUF
12h 27m1 stop
$385JetBlue
Find Deal
Wed, Oct 22 - Tue, Oct 28
JetBlue Logo
9:20 pm - 10:03 amBUF-SDQ
11h 43m1 stop
JetBlue Logo
6:00 am - 1:34 pmSDQ-BUF
8h 34m1 stop
$387JetBlue
Find Deal
Sun, Mar 1 - Thu, Mar 5
American Airlines Logo
6:07 am - 3:20 pmBUF-SDQ
9h 13m2 stops
American Airlines Logo
2:45 pm - 11:42 pmSDQ-BUF
8h 57m2 stops
$402American Airlines
Find Deal
Wed, Oct 22 - Wed, Oct 29
United Airlines Logo
5:55 pm - 2:10 pmBUF-SDQ
20h 15m2 stops
United Airlines Logo
1:53 pm - 10:58 pmSDQ-BUF
9h 05m1 stop
$449United Airlines
Find Deal
Wed, Oct 22 - Wed, Oct 29
United Airlines Logo
7:00 am - 11:46 pmBUF-SDQ
15h 46m2 stops
United Airlines Logo
6:00 am - 12:26 pmSDQ-BUF
7h 26m1 stop
$492United Airlines
Find Deal
Sun, Mar 1 - Thu, Mar 5
Delta Logo
7:00 am - 6:35 pmBUF-SDQ
10h 35m1 stop
Delta Logo
3:40 pm - 10:37 amSDQ-BUF
19h 57m2 stops
$493Delta
Find Deal
Tue, Feb 10 - Tue, Feb 24
Delta Logo
7:00 am - 6:35 pmBUF-SDQ
10h 35m1 stop
Delta Logo
7:05 am - 6:51 pmSDQ-BUF
12h 46m1 stop
$522Delta
Find Deal
Tue, Feb 10 - Fri, Feb 20
American Airlines Logo
6:49 pm - 1:35 pmBUF-SDQ
18h 46m2 stops
American Airlines Logo
4:20 pm - 12:10 pmSDQ-BUF
19h 50m2 stops
$581American Airlines
Find Deal
Fri, Sep 19 - Fri, Sep 26
Frontier Logo
3:29 pm - 10:11 amBUF-SDQ
17h 42m1 stop
Frontier Logo
10:56 am - 8:13 amSDQ-BUF
22h 17m1 stop
$729Frontier
Find Deal
Sun, Jan 4 - Sun, Jan 11

Delta flights from Buffalo to Santo Domingo

Our best Delta deals on Buffalo to Santo Domingo flight tickets
Delta
Feb 10
BUF7:00 amBuffalo
10h 35m
1 stop
SDQ6:35 pmSanto Domingo Las Americas
Feb 24
SDQ3:40 pmSanto Domingo Las Americas
19h 57m
2 stops
BUF10:37 amBuffalo
$493
Find similar
Delta
Feb 10
BUF7:00 amBuffalo
10h 35m
1 stop
SDQ6:35 pmSanto Domingo Las Americas
Feb 20
SDQ7:05 amSanto Domingo Las Americas
12h 46m
1 stop
BUF6:51 pmBuffalo
$522
Find similar
Delta
Feb 10
BUF2:30 pmBuffalo
22h 45m
2 stops
SDQ2:15 pmSanto Domingo Las Americas
Feb 20
SDQ7:05 amSanto Domingo Las Americas
12h 46m
1 stop
BUF6:51 pmBuffalo
$652
Find similar

JetBlue flights from Buffalo to Santo Domingo

Our best JetBlue deals on Buffalo to Santo Domingo flight tickets
JetBlue
Oct 22
BUF9:38 amBuffalo
7h 17m
1 stop
SDQ4:55 pmSanto Domingo Las Americas
Oct 29
SDQ2:30 pmSanto Domingo Las Americas
7h 57m
1 stop
BUF10:27 pmBuffalo
$384
Find similar
JetBlue
Oct 22
BUF3:55 pmBuffalo
7h 42m
1 stop
SDQ11:37 pmSanto Domingo Las Americas
Oct 28
SDQ3:12 amSanto Domingo Las Americas
12h 27m
1 stop
BUF3:39 pmBuffalo
$385
Find similar
JetBlue
Mar 1
BUF9:20 pmBuffalo
11h 43m
1 stop
SDQ10:03 amSanto Domingo Las Americas
Mar 5
SDQ6:00 amSanto Domingo Las Americas
8h 34m
1 stop
BUF1:34 pmBuffalo
$387
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 8, 2025.
Use the filters below to find and compare flights from Buffalo to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 10/22

9:38 am-4:55 pm

1 stop7h 17m

Santo Domingo Las Americas

Wed 10/29

2:30 pm-10:27 pm

1 stop7h 57m

$384

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 10/22

3:55 pm-11:37 pm

1 stop7h 42m

Santo Domingo Las Americas

Tue 10/28

3:12 am-3:39 pm

1 stop12h 27m

$385

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 3/1

9:20 pm-10:03 am

1 stop11h 43m

Santo Domingo Las Americas

Thu 3/5

6:00 am-1:34 pm

1 stop8h 34m

$387

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 10/22

6:07 am-3:20 pm

2 stops9h 13m

Santo Domingo Las Americas

Wed 10/29

2:45 pm-11:42 pm

2 stops8h 57m

$402

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 10/22

5:55 pm-2:10 pm

2 stops20h 15m

Santo Domingo Las Americas

Wed 10/29

1:53 pm-10:58 pm

1 stop9h 05m

$449

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 3/1

7:00 am-11:46 pm

2 stops15h 46m

Santo Domingo Las Americas

Thu 3/5

6:00 am-12:26 pm

1 stop7h 26m

$492

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Tue 2/10

7:00 am-6:35 pm

1 stop10h 35m

Santo Domingo Las Americas

Tue 2/24

3:40 pm-10:37 am

2 stops19h 57m

$493

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Tue 2/10

7:00 am-6:35 pm

1 stop10h 35m

Santo Domingo Las Americas

Fri 2/20

7:05 am-6:51 pm

1 stop12h 46m

$522

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Fri 9/19

6:49 pm-1:35 pm

2 stops18h 46m

Santo Domingo Las Americas

Fri 9/26

4:20 pm-12:10 pm

2 stops19h 50m

$581

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 1/4

3:29 pm-10:11 am

1 stop17h 42m

Santo Domingo Las Americas

Sun 1/11

10:56 am-8:13 am

1 stop22h 17m

$729

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Buffalo to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in September, then you should wait until August to fly from Buffalo, when ticket prices are also cheap, with an average price of $438.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Tuesday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $409. The most expensive day to fly to Santo Domingo is Sunday, with ticket prices averaging around $728.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the evening when flights can be purchased for as low as $465. Try not to purchase tickets in the morning because they tend to be around $567. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Buffalo to Santo Domingo flights?

You could potentially save up to 12% on your flight if you consider stops on a Buffalo to Santo Domingo flight.

When to book flights from Buffalo to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to Santo Domingo (BUF to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Santo Domingo

Direct flights

None
There are no direct flights from Buffalo to Santo Domingo. There are no popular flight routes from Buffalo to Santo Domingo.
Search flight deals

  • How far is Buffalo to Santo Domingo Las Americas by plane?

    Santo Domingo Las Americas is 1764.1 mi away from Buffalo. By plane, this route typically takes 6h 49m.

  • When did momondo last update prices for flights from Buffalo Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Buffalo Airport to Santo Domingo Las Americas Airport are updated daily.

  • How many operators does momondo search for flights from Buffalo Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Buffalo Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Buffalo to Santo Domingo?

Best airlines flying from Buffalo to Santo Domingo

Compare and see reviews for airlines that fly from Buffalo to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $422Free CancellationRating
7.2
2,914 reviews
Search JetBlue flights
DeltaPriceFrom $432Free CancellationRating
7.9
7,966 reviews
Search Delta flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Santo Domingo?

Finding the right flight to Santo Domingo from Buffalo is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santo Domingo quick and easy, saving you time and money.

Can I find flights from Buffalo to Santo Domingo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santo Domingo from Buffalo with this policy.

How can momondo help me find flights from Buffalo to Santo Domingo?

momondo provides multiple filters to help you find the best flight to Santo Domingo from Buffalo. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Buffalo to Santo Domingo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Buffalo to Santo Domingo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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