Enjoy one of Mount Vernon’s most comfortable and conveniently located hotels. Holiday Inn Express & Suites Mount Vernon features a fresh, contemporary design with smart amenities suited for today’s business and leisure travelers. Our central location offers easy access to Interstates 57 and 64, making travel in and out of the area simple and efficient. The hotel is conveniently located near key corporate and medical partners including Continental Tire, Walgreens Distribution Center, Good Samaritan Hospital, and SSM, making it an ideal choice for corporate travelers visiting the area. Guests looking to explore will find plenty to see and do nearby. Experience local culture at The Cedarhurst Center for the Arts, home to the Mitchell Museum and Kuenz Sculpture Park, or visit the Jefferson County Historical Village. Family friendly attractions include the Aquatic Zoo Waterpark, while outdoor enthusiasts can enjoy Rend Lake for boating, fishing, hiking, and swimming, as well as the 27 hole Rend Lake Golf Course. Our non smoking hotel offers an indoor heated salt water pool and a warm, welcoming Great Room with an outdoor patio and Suite Shop. Complimentary amenities include a hot breakfast buffet, 24 hour Fitness Center, and reliable high speed wireless Internet. Experience genuine Midwest hospitality and allow us to make Holiday Inn Express & Suites Mount Vernon your home away from home.