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Cheap flights from the United States to Panama City from $105

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from the United States to Panama City departing on 10/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from the United States to Panama City

Recent round-trip flight deals from the United States to Panama City

Avianca Logo
2:35 pm - 12:10 amORD-PTY
9h 35m1 stop
Avianca Logo
2:55 am - 9:20 pmPTY-ORD
18h 25m1 stop
$272Avianca
Find Deal
Thu, Oct 23 - Sun, Oct 26
Avianca Logo
2:35 pm - 12:10 amORD-PTY
9h 35m1 stop
Avianca Logo
2:55 am - 9:20 pmPTY-ORD
18h 25m1 stop
$275Avianca
Find Deal
Thu, Oct 23 - Wed, Oct 29
Copa Airlines Logo
12:46 pm - 3:54 pmMIA-PTY
3h 08mnonstop
Copa Airlines Logo
3:39 pm - 6:51 pmPTY-MIA
3h 12mnonstop
$276Copa Airlines
Find Deal
Fri, Nov 21 - Tue, Nov 25
American Airlines Logo
12:23 pm - 2:31 pmMIA-PTY
3h 08mnonstop
American Airlines Logo
3:31 pm - 7:39 pmPTY-MIA
3h 08mnonstop
$281American Airlines
Find Deal
Thu, Sep 25 - Sun, Sep 28
Copa Airlines Logo
4:59 am - 8:06 amMIA-PTY
3h 07mnonstop
Copa Airlines Logo
6:11 pm - 9:22 pmPTY-MIA
3h 11mnonstop
$290Copa Airlines
Find Deal
Thu, Nov 27 - Mon, Dec 1
American Airlines Logo
12:23 pm - 2:31 pmMIA-PTY
3h 08mnonstop
American Airlines Logo
1:45 pm - 5:52 pmPTY-MIA
3h 07mnonstop
$302American Airlines
Find Deal
Sun, Sep 28 - Tue, Sep 30
United Airlines Logo
9:00 am - 7:38 pmMIA-PTY
10h 38m1 stop
United Airlines Logo
11:35 am - 9:43 pmPTY-MIA
10h 08m1 stop
$319United Airlines
Find Deal
Sat, Dec 6 - Tue, Dec 16
United Airlines Logo
6:00 am - 1:45 pmDCA-PTY
8h 45m1 stop
United Airlines Logo
10:00 am - 7:35 pmPTY-DCA
9h 35m1 stop
$450United Airlines
Find Deal
Sat, Nov 1 - Tue, Nov 4
Delta Logo
5:30 am - 12:55 pmORD-PTY
7h 25m1 stop
Delta Logo
2:10 pm - 11:54 pmPTY-ORD
9h 44m1 stop
$465Delta
Find Deal
Sat, Sep 27 - Fri, Oct 3
Delta Logo
12:35 pm - 8:04 pmIAD-PTY
7h 29m1 stop
Delta Logo
8:05 am - 6:42 pmPTY-IAD
10h 37m1 stop
$472Delta
Find Deal
Sat, Jan 10 - Sat, Jan 17

Copa Airlines flights from United States to Panama City

Our best Copa Airlines deals on United States to Panama City flight tickets
Copa Airlines
Nov 21
MIA12:46 pmMiami
3h 08m
PTY3:54 pmPanama City Tocumen Intl
Nov 25
PTY3:39 pmPanama City Tocumen Intl
3h 12m
MIA6:51 pmMiami
$276
Find similar
Copa Airlines
Nov 27
MIA4:59 amMiami
3h 07m
PTY8:06 amPanama City Tocumen Intl
Dec 1
PTY6:11 pmPanama City Tocumen Intl
3h 11m
MIA9:22 pmMiami
$290
Find similar
Copa Airlines
Dec 4
MIA12:47 pmMiami
3h 08m
PTY3:55 pmPanama City Tocumen Intl
Dec 8
PTY12:33 pmPanama City Tocumen Intl
3h 12m
MIA3:45 pmMiami
$305
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British Airways flights from United States to Panama City

Our best British Airways deals on United States to Panama City flight tickets
British Airways
Sep 28
DCA6:00 amWashington, D.C. Reagan-National
9h 31m
1 stop
PTY2:31 pmPanama City Tocumen Intl
Oct 7
PTY3:15 pmPanama City Tocumen Intl
17h 09m
2 stops
DCA9:24 amWashington, D.C. Reagan-National
$455
Find similar
British Airways
Sep 28
DCA6:00 amWashington, D.C. Reagan-National
9h 31m
1 stop
PTY2:31 pmPanama City Tocumen Intl
Oct 7
PTY3:15 pmPanama City Tocumen Intl
7h 44m
1 stop
DCA11:59 pmWashington, D.C. Reagan-National
$559
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from United States to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from the United States to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 10/23

2:35 pm-12:10 am

1 stop9h 35m

Panama City Tocumen Intl

Sun 10/26

2:55 am-9:20 pm

1 stop18h 25m

$272

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 10/23

2:35 pm-12:10 am

1 stop9h 35m

Panama City Tocumen Intl

Wed 10/29

2:55 am-9:20 pm

1 stop18h 25m

$275

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Fri 11/21

12:46 pm-3:54 pm

Nonstop3h 08m

Panama City Tocumen Intl

Tue 11/25

3:39 pm-6:51 pm

Nonstop3h 12m

$276

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Thu 9/25

12:23 pm-2:31 pm

Nonstop3h 08m

Panama City Tocumen Intl

Sun 9/28

3:31 pm-7:39 pm

Nonstop3h 08m

$281

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Thu 11/27

4:59 am-8:06 am

Nonstop3h 07m

Panama City Tocumen Intl

Mon 12/1

6:11 pm-9:22 pm

Nonstop3h 11m

$290

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Sun 9/28

12:23 pm-2:31 pm

Nonstop3h 08m

Panama City Tocumen Intl

Tue 9/30

1:45 pm-5:52 pm

Nonstop3h 07m

$302

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Sat 12/6

9:00 am-7:38 pm

1 stop10h 38m

Panama City Tocumen Intl

Tue 12/16

11:35 am-9:43 pm

1 stop10h 08m

$319

Washington, D.C.Panama City

DCA - PTY

DCAPTY

Washington, D.C. Reagan-National

Sat 11/1

6:00 am-1:45 pm

1 stop8h 45m

Panama City Tocumen Intl

Tue 11/4

10:00 am-7:35 pm

1 stop9h 35m

$450

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sat 9/27

5:30 am-12:55 pm

1 stop7h 25m

Panama City Tocumen Intl

Fri 10/3

2:10 pm-11:54 pm

1 stop9h 44m

$465

Washington, D.C.Panama City

IAD - PTY

IADPTY

Washington, D.C. Dulles Intl

Sat 1/10

12:35 pm-8:04 pm

1 stop7h 29m

Panama City Tocumen Intl

Sat 1/17

8:05 am-6:42 pm

1 stop10h 37m

$472

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from United States to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, October is the cheapest month to fly from United States to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $473. If you’re not able to fly to Panama City in October, then September is your next best option. Flight prices from United States to Panama City during September average around $488.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Wednesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $579. If your travel schedule is flexible, try to avoid departing on a Friday because tickets tend to average around $627. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from United States to Panama City during this time can be as low as $546. Try not to purchase tickets in the morning because they tend to be around $656. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest United States to Panama City Tocumen Intl flight route?

Fly from Miami to Panama City Tocumen Intl for the best United States - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from United States when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $585 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from United States for as low as $524 on momondo.

What cabin class options are available on United States to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on United States to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on United States to Panama City flights?

You could potentially save up to 11% on your flight if you consider stops on a United States to Panama City flight.

Cheap United States to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from United States to Panama City

Best Price Found

$139

Fastest flight time

2h 55m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from United States in the past 72 hours is $139. The best round-trip flight deal from United States to Panama City found on momondo in the last 72 hours is $285.
The fastest flight from United States to Panama City takes 2h 55m
Direct flights go from United States to Panama City every day.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
Search flight deals

  • When did momondo last update prices for flights from United States to Panama City Tocumen Intl Airport?

    Prices for flights from United States to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from United States to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from United States to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from United States to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The necessary travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from United States to Panama City?

Best airlines flying from United States to Panama City

Compare and see reviews for airlines that fly from United States to Panama City with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $132Free CancellationRating
6.7
2,436 reviews
Search Avianca flights
DeltaPriceFrom $167Free CancellationRating
7.9
7,960 reviews
Search Delta flights
American AirlinesPriceFrom $203Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
Copa AirlinesPriceFrom $222Free CancellationRating
7.6
1,531 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $290Free CancellationRating
7.4
8,937 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from United States to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from United States to Panama City for you.

Can I find flights from United States to Panama City with flexible booking policies on momondo?

Flights from United States to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from United States to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from United States. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from United States to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from United States are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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