Cheap flights from the United States to Panama City from $134

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from the United States to Panama City departing on 4/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from the United States to Panama City

Recent round-trip flight deals from the United States to Panama City

Enter your travel dates to find the best prices.
Avianca Logo
2:05 am - 8:50 am
MIA
-
PTY
6h 45m1 stop
Avianca Logo
2:55 pm - 10:30 pm
PTY
-
MIA
7h 35m1 stop
$299Avianca
Thu, Jan 22 - Sun, Jan 25
Avianca Logo
7:05 am - 6:55 pm
MIA
-
PTY
11h 50m1 stop
Avianca Logo
2:55 pm - 3:10 am
PTY
-
MIA
12h 15m1 stop
$300Avianca
Thu, Jan 15 - Thu, Jan 22
Avianca Logo
7:00 am - 2:00 pm
MIA
-
PTY
7h 00m1 stop
Avianca Logo
2:55 pm - 10:30 pm
PTY
-
MIA
7h 35m1 stop
$308Avianca
Mon, Jan 19 - Mon, Jan 26
Multiple Airlines Logo
9:57 am - 1:00 am
ATL
-
PTY
15h 03m2 stops
Multiple Airlines Logo
2:55 pm - 9:07 am
PTY
-
ATL
18h 12m2 stops
$387Multiple Airlines
Thu, Feb 5 - Sun, Feb 22
Multiple Airlines Logo
10:12 am - 1:00 am
ATL
-
PTY
14h 48m2 stops
Multiple Airlines Logo
2:55 pm - 9:07 am
PTY
-
ATL
18h 12m2 stops
$388Multiple Airlines
Thu, Feb 19 - Wed, Feb 25
Copa Airlines Logo
2:42 pm - 5:10 pm
MCO
-
PTY
3h 28mnonstop
Copa Airlines Logo
6:02 pm - 10:40 pm
PTY
-
MCO
3h 38mnonstop
$411Copa Airlines
Sun, Apr 19 - Sun, Apr 26
United Airlines Logo
11:51 am - 6:37 pm
MCO
-
PTY
7h 46m1 stop
United Airlines Logo
7:55 am - 8:09 pm
PTY
-
MCO
11h 14m1 stop
$414United Airlines
Fri, May 15 - Sun, May 24
United Airlines Logo
3:06 pm - 2:14 pm
MCO
-
PTY
24h 08m1 stop
United Airlines Logo
7:55 am - 8:09 pm
PTY
-
MCO
11h 14m1 stop
$416United Airlines
Fri, May 15 - Sun, May 24
Delta Logo
9:59 am - 1:03 pm
ATL
-
PTY
4h 04mnonstop
Delta Logo
2:20 pm - 7:40 pm
PTY
-
ATL
4h 20mnonstop
$429Delta
Mon, Mar 30 - Sun, May 3
Copa Airlines Logo
3:05 pm - 8:41 pm
BOS
-
PTY
5h 36mnonstop
Copa Airlines Logo
4:18 pm - 10:10 pm
PTY
-
BOS
5h 52mnonstop
$545Copa Airlines
Sun, Mar 1 - Wed, Mar 4

Copa Airlines flights from United States to Panama City

Our best Copa Airlines deals on United States to Panama City flight tickets
Copa Airlines
Apr 19
MCO2:42 pmOrlando
3h 28m
PTY5:10 pmPanama City Tocumen Intl
Apr 26
PTY6:02 pmPanama City Tocumen Intl
3h 38m
MCO10:40 pmOrlando
Copa Airlines
Mar 11
MCO2:43 pmOrlando
3h 25m
PTY5:08 pmPanama City Tocumen Intl
Mar 21
PTY9:30 amPanama City Tocumen Intl
3h 30m
MCO2:00 pmOrlando
Copa Airlines
Mar 14
ATL5:30 pmAtlanta Hartsfield-Jackson
4h 04m
PTY8:34 pmPanama City Tocumen Intl
Mar 21
PTY10:26 amPanama City Tocumen Intl
4h 20m
ATL3:46 pmAtlanta Hartsfield-Jackson

American Airlines flights from United States to Panama City

Our best American Airlines deals on United States to Panama City flight tickets
American Airlines
Feb 26
MCO7:00 amOrlando
8h 15m
1 stop
PTY3:15 pmPanama City Tocumen Intl
Mar 9
PTY1:39 pmPanama City Tocumen Intl
19h 27m
2 stops
MCO10:06 amOrlando
American Airlines
May 15
MCO3:36 pmOrlando
21h 39m
2 stops
PTY12:15 pmPanama City Tocumen Intl
May 24
PTY1:50 pmPanama City Tocumen Intl
8h 50m
1 stop
MCO11:40 pmOrlando
American Airlines
Jan 24
ATL9:00 amAtlanta Hartsfield-Jackson
6h 52m
1 stop
PTY3:52 pmPanama City Tocumen Intl
Jan 31
PTY5:00 pmPanama City Tocumen Intl
16h 48m
2 stops
ATL9:48 amAtlanta Hartsfield-Jackson

momondo Fare Finder

 
Customize your flight search to find flights from United States to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from the United States to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Thu 1/22

2:05 am-8:50 am

1 stop6h 45m

Panama City Tocumen Intl

Sun 1/25

2:55 pm-10:30 pm

1 stop7h 35m

$299

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Thu 1/15

7:05 am-6:55 pm

1 stop11h 50m

Panama City Tocumen Intl

Thu 1/22

2:55 pm-3:10 am

1 stop12h 15m

$300

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Mon 1/19

7:00 am-2:00 pm

1 stop7h 00m

Panama City Tocumen Intl

Mon 1/26

2:55 pm-10:30 pm

1 stop7h 35m

$308

AtlantaPanama City

ATL - PTY

ATLPTY

Atlanta Hartsfield-Jackson

Thu 2/5

9:57 am-1:00 am

2 stops15h 03m

Panama City Tocumen Intl

Sun 2/22

2:55 pm-9:07 am

2 stops18h 12m

$387

AtlantaPanama City

ATL - PTY

ATLPTY

Atlanta Hartsfield-Jackson

Thu 2/19

10:12 am-1:00 am

2 stops14h 48m

Panama City Tocumen Intl

Wed 2/25

2:55 pm-9:07 am

2 stops18h 12m

$388

OrlandoPanama City

MCO - PTY

MCOPTY

Orlando

Sun 4/19

2:42 pm-5:10 pm

Nonstop3h 28m

Panama City Tocumen Intl

Sun 4/26

6:02 pm-10:40 pm

Nonstop3h 38m

$411

OrlandoPanama City

MCO - PTY

MCOPTY

Orlando

Fri 5/15

11:51 am-6:37 pm

1 stop7h 46m

Panama City Tocumen Intl

Sun 5/24

7:55 am-8:09 pm

1 stop11h 14m

$414

OrlandoPanama City

MCO - PTY

MCOPTY

Orlando

Fri 5/15

3:06 pm-2:14 pm

1 stop24h 08m

Panama City Tocumen Intl

Sun 5/24

7:55 am-8:09 pm

1 stop11h 14m

$416

AtlantaPanama City

ATL - PTY

ATLPTY

Atlanta Hartsfield-Jackson

Mon 3/30

9:59 am-1:03 pm

Nonstop4h 04m

Panama City Tocumen Intl

Sun 5/3

2:20 pm-7:40 pm

Nonstop4h 20m

$429

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Sun 3/1

3:05 pm-8:41 pm

Nonstop5h 36m

Panama City Tocumen Intl

Wed 3/4

4:18 pm-10:10 pm

Nonstop5h 52m

$545

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from United States to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from United States to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $528. If you’re not able to fly to Panama City in September, then June is your next best option. Flight prices from United States to Panama City during June average around $553.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $576. If your travel schedule is flexible, try to avoid departing on a Friday because tickets tend to average around $632. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from United States to Panama City during this time can be as low as $553. Try not to purchase tickets in the morning because they tend to be around $670. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest United States to Panama City Tocumen Intl flight route?

Fly from Miami to Panama City Tocumen Intl for the best United States - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from United States when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $613 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from United States for as low as $539 on momondo.

What cabin class options are available on United States to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on United States to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on United States to Panama City flights?

You could potentially save up to 34% on your flight if you consider stops on a United States to Panama City flight.

Cheap United States to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from United States to Panama City

Best Price Found

$171

Fastest flight time

3h 04m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from United States in the past 72 hours is $171. The best round-trip flight deal from United States to Panama City found on momondo in the last 72 hours is $302.
The fastest flight from United States to Panama City takes 3h 04m
Direct flights go from United States to Panama City every day.
There is 1 airport in Panama City. From United States there are direct flights to Panama City Tocumen Intl (PTY).
  • When did momondo last update prices for flights from United States to Panama City Tocumen Intl Airport?

    Prices for flights from United States to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from United States to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from United States to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from United States to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The necessary travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from United States to Panama City?

Best airlines flying from United States to Panama City

Compare and see reviews for airlines that fly from United States to Panama City with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $136Free CancellationRating
6.6
2,488 reviews
Search Avianca flights
DeltaPriceFrom $147Free CancellationRating
7.9
8,016 reviews
Search Delta flights
American AirlinesPriceFrom $203Free CancellationRating
7.2
11,070 reviews
Search American Airlines flights
Copa AirlinesPriceFrom $242Free CancellationRating
7.6
1,561 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $290Free CancellationRating
7.4
9,114 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from United States to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from United States to Panama City for you.

Can I find flights from United States to Panama City with flexible booking policies on momondo?

Flights from United States to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from United States to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from United States. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from United States to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from United States are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
Tue 1/27
Tue 2/3

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