What is the cheapest airline that flies from South Carolina to Panama City Tocumen Intl?

JetBlue, Delta, and United Airlines are the most popular carriers operating from South Carolina to Panama City Tocumen Intl

How long does it take to fly to Panama City?

If you’re flying from a popular airport in South Carolina, such as Greenville or Myrtle Beach, and flying into Panama City, then you can expect flight times to average 5h 53m and 7h 59m, respectively.

What airlines fly to Panama City?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Panama City from South Carolina according to our data. American Airlines is the first choice among our users, with 46% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 3 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from South Carolina to Panama City Tocumen Intl Airport?

Prices for flights from South Carolina to Panama City Tocumen Intl Airport are refreshed on a daily basis.

How many operators does momondo search for flights from South Carolina to Panama City Tocumen Intl Airport?

As of August 2026, there are 4 operators available to choose from for flights from South Carolina to Panama City Tocumen Intl Airport.

How old do you have to be to fly from South Carolina to Panama City Tocumen Intl Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Panama City Tocumen Intl Airport.

What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$250 Cheap Flights from South Carolina to Panama City in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Panama City

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:25 pm - 2:55 pmCHS Charleston-PTY Panama City Tocumen Intl

18h 30m3 stops New York John F Kennedy Intl Guatemala City La Aurora San José Juan Santamaria Intl

3:50 pm - 9:59 amPTY Panama City Tocumen Intl-CHS Charleston

18h 09m2 stops San Salvador El Salvador Intl New York John F Kennedy Intl

$559Multiple Airlines

Sun, Nov 1 - Sun, Nov 8

8:25 pm - 10:30 amCHS Charleston-PTY Panama City Tocumen Intl

15h 05m2 stops New York John F Kennedy Intl San Salvador El Salvador Intl

11:25 am - 9:59 amPTY Panama City Tocumen Intl-CHS Charleston

22h 34m3 stops San José Juan Santamaria Intl Guatemala City La Aurora New York John F Kennedy Intl

$559Multiple Airlines

Thu, Oct 22 - Sun, Nov 1

10:10 am - 10:30 amCHS Charleston-PTY Panama City Tocumen Intl

24h 20m2 stops New York John F Kennedy Intl San Salvador El Salvador Intl

7:50 pm - 9:20 amPTY Panama City Tocumen Intl-CHS Charleston

13h 30m2 stops San Salvador El Salvador Intl New York John F Kennedy Intl

$561Multiple Airlines

Wed, Jan 20 - Wed, Jan 27

7:40 am - 1:59 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

6h 19m1 stop Atlanta Hartsfield-Jackson

3:30 pm - 11:54 pmPTY Panama City Tocumen Intl-CLT Charlotte Douglas

8h 24m1 stop Atlanta Hartsfield-Jackson

$579Delta

Thu, Nov 5 - Tue, Nov 10

6:00 am - 1:59 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

7h 59m1 stop Atlanta Hartsfield-Jackson

3:30 pm - 11:54 pmPTY Panama City Tocumen Intl-CLT Charlotte Douglas

8h 24m1 stop Atlanta Hartsfield-Jackson

$579Delta

Wed, Nov 4 - Mon, Nov 9

11:00 am - 7:31 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

9h 31m1 stop Newark

9:30 am - 9:41 pmPTY Panama City Tocumen Intl-CLT Charlotte Douglas

11h 11m1 stop Newark

$579United Airlines

Wed, Oct 21 - Wed, Oct 28

6:00 am - 8:02 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

14h 02m1 stop Newark

10:00 am - 9:41 pmPTY Panama City Tocumen Intl-CLT Charlotte Douglas

11h 41m1 stop Newark

$579United Airlines

Thu, Nov 12 - Mon, Nov 16

10:44 pm - 1:02 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

15h 18m1 stop Miami

2:02 pm - 8:24 amPTY Panama City Tocumen Intl-CLT Charlotte Douglas

17h 22m1 stop Miami

$579American Airlines

Mon, Oct 12 - Fri, Oct 16

10:44 pm - 1:02 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

15h 18m1 stop Miami

2:02 pm - 11:49 pmPTY Panama City Tocumen Intl-CLT Charlotte Douglas

8h 47m1 stop Miami

$579American Airlines

Mon, Oct 19 - Fri, Oct 23

6:00 am - 1:59 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

7h 59m1 stop Atlanta Hartsfield-Jackson

3:30 pm - 11:54 pmPTY Panama City Tocumen Intl-CLT Charlotte Douglas

8h 24m1 stop Atlanta Hartsfield-Jackson

$579Delta

Thu, Nov 5 - Mon, Nov 9

Cheap last minute flights

Enter your travel dates to find the best prices.

7:00 am - 6:37 pmCHS Charleston-PTY Panama City Tocumen Intl

12h 37m1 stop Houston George Bush Intcntl

10:55 pm - 2:13 pmPTY Panama City Tocumen Intl-CHS Charleston

14h 18m1 stop Newark

$687United Airlines

Thu, Aug 13 - Tue, Aug 25

7:00 am - 6:37 pmCHS Charleston-PTY Panama City Tocumen Intl

12h 37m1 stop Houston George Bush Intcntl

9:45 am - 11:59 pmPTY Panama City Tocumen Intl-CHS Charleston

13h 14m1 stop Newark

$687United Airlines

Mon, Aug 17 - Thu, Aug 27

5:10 am - 12:55 pmCHS Charleston-PTY Panama City Tocumen Intl

8h 45m1 stop Atlanta Hartsfield-Jackson

2:20 pm - 8:58 amPTY Panama City Tocumen Intl-CHS Charleston

17h 38m1 stop Atlanta Hartsfield-Jackson

$721Delta

Fri, Aug 14 - Thu, Aug 27

6:00 am - 12:39 pmCHS Charleston-PTY Panama City Tocumen Intl

7h 39m1 stop Miami

1:39 pm - 11:59 pmPTY Panama City Tocumen Intl-CHS Charleston

9h 20m1 stop Miami

$721American Airlines

Sat, Aug 15 - Wed, Aug 26

11:03 am - 1:55 amCHS Charleston-PTY Panama City Tocumen Intl

39h 52m2 stops New York John F Kennedy Intl San Salvador El Salvador Intl

11:25 am - 10:08 amPTY Panama City Tocumen Intl-CHS Charleston

21h 43m3 stops San José Juan Santamaria Intl Guatemala City La Aurora New York John F Kennedy Intl

$728Multiple Airlines

Sat, Aug 15 - Wed, Aug 26

9:48 am - 12:55 pmCHS Charleston-PTY Panama City Tocumen Intl

28h 07m1 stop Atlanta Hartsfield-Jackson

2:20 pm - 11:59 pmPTY Panama City Tocumen Intl-CHS Charleston

8h 39m1 stop Atlanta Hartsfield-Jackson

$729Delta

Mon, Aug 17 - Fri, Aug 28

7:05 am - 12:39 pmCLT Charlotte Douglas-PTY Panama City Tocumen Intl

6h 34m1 stop Miami

1:39 pm - 9:55 amPTY Panama City Tocumen Intl-CLT Charlotte Douglas

19h 16m1 stop Miami

$772American Airlines

Sat, Aug 15 - Mon, Aug 17

7:55 pm - 10:22 amCLT Charlotte Douglas-PTY Panama City Tocumen Intl

15h 27m1 stop Washington, D.C. Dulles Intl

9:13 am - 6:56 pmPTY Panama City Tocumen Intl-CLT Charlotte Douglas

8h 43m1 stop Washington, D.C. Dulles Intl

$1,008Copa Airlines

Mon, Aug 17 - Sat, Aug 22

7:55 pm - 10:22 amCLT Charlotte Douglas-PTY Panama City Tocumen Intl

15h 27m1 stop Washington, D.C. Dulles Intl

9:13 am - 6:56 pmPTY Panama City Tocumen Intl-CLT Charlotte Douglas

8h 43m1 stop Washington, D.C. Dulles Intl

$1,032Copa Airlines

Mon, Aug 17 - Sat, Aug 22

9:43 am - 1:55 amSAV Savannah/Hilton Head-PTY Panama City Tocumen Intl

17h 12m2 stops Boston Logan Intl San Salvador El Salvador Intl

3:50 pm - 10:04 amPTY Panama City Tocumen Intl-SAV Savannah/Hilton Head

41h 14m2 stops San Salvador El Salvador Intl Boston Logan Intl

$1,079Multiple Airlines

Sun, Aug 16 - Mon, Aug 17

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

United Airlines flights from South Carolina to Panama City

Our best United Airlines deals on South Carolina to Panama City flight tickets

United Airlines

Oct 5

CLT9:54 amCharlotte Douglas

10h 37m

1 stop

PTY7:31 pmPanama City Tocumen Intl

Oct 7

PTY9:45 amPanama City Tocumen Intl

23h 23m

2 stops

CLT10:08 amCharlotte Douglas

$583

United Airlines

Oct 5

CLT11:00 amCharlotte Douglas

9h 31m

1 stop

PTY7:31 pmPanama City Tocumen Intl

Oct 7

PTY9:45 amPanama City Tocumen Intl

10h 30m

1 stop

CLT9:15 pmCharlotte Douglas

$599

United Airlines

Oct 1

CHS6:00 amCharleston

14h 31m

2 stops

PTY7:31 pmPanama City Tocumen Intl

Oct 5

PTY3:30 pmPanama City Tocumen Intl

17h 57m

2 stops

CHS10:27 amCharleston

$601

GOL flights from South Carolina to Panama City

Our best GOL deals on South Carolina to Panama City flight tickets

GOL

Aug 28

AGS5:40 pmAugusta Bush Field

19h 59m

2 stops

PTY12:39 pmPanama City Tocumen Intl

Sep 6

PTY1:39 pmPanama City Tocumen Intl

32h 07m

2 stops

AGS10:46 pmAugusta Bush Field

$971

GOL

Nov 10

AGS5:17 pmAugusta Bush Field

20h 56m

2 stops

PTY2:13 pmPanama City Tocumen Intl

Nov 14

PTY3:13 pmPanama City Tocumen Intl

17h 18m

2 stops

AGS8:31 amAugusta Bush Field

$996

GOL

Dec 6

AGS6:07 pmAugusta Bush Field

20h 06m

2 stops

PTY2:13 pmPanama City Tocumen Intl

Jan 3

PTY2:51 pmPanama City Tocumen Intl

21h 25m

2 stops

AGS12:16 pmAugusta Bush Field

$1,078

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Sun 11/1

8:25 pm-2:55 pm

3 stops18h 30m

Panama City Tocumen Intl

Sun 11/8

3:50 pm-9:59 am

2 stops18h 09m

$559

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Thu 10/22

8:25 pm-10:30 am

2 stops15h 05m

Panama City Tocumen Intl

Sun 11/1

11:25 am-9:59 am

3 stops22h 34m

$559

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Wed 1/20

10:10 am-10:30 am

2 stops24h 20m

Panama City Tocumen Intl

Wed 1/27

7:50 pm-9:20 am

2 stops13h 30m

$561

Quickest round-trip

CharlottePanama City

CLT Charlotte Douglas - PTY Panama City Tocumen Intl

CLTPTY

Charlotte Douglas

Thu 11/5

7:40 am-1:59 pm

1 stop6h 19m

Panama City Tocumen Intl

Tue 11/10

3:30 pm-11:54 pm

1 stop8h 24m

$579

CharlottePanama City

CLT Charlotte Douglas - PTY Panama City Tocumen Intl

CLTPTY

Charlotte Douglas

Wed 11/4

6:00 am-1:59 pm

1 stop7h 59m

Panama City Tocumen Intl

Mon 11/9

3:30 pm-11:54 pm

1 stop8h 24m

$579

CharlottePanama City

CLT Charlotte Douglas - PTY Panama City Tocumen Intl

CLTPTY

Charlotte Douglas

Wed 10/21

11:00 am-7:31 pm

1 stop9h 31m

Panama City Tocumen Intl

Wed 10/28

9:30 am-9:41 pm

1 stop11h 11m

$579

CharlottePanama City

CLT Charlotte Douglas - PTY Panama City Tocumen Intl

CLTPTY

Charlotte Douglas

Thu 11/12

6:00 am-8:02 pm

1 stop14h 02m

Panama City Tocumen Intl

Mon 11/16

10:00 am-9:41 pm

1 stop11h 41m

$579

CharlottePanama City

CLT Charlotte Douglas - PTY Panama City Tocumen Intl

CLTPTY

Charlotte Douglas

Mon 10/12

10:44 pm-1:02 pm

1 stop15h 18m

Panama City Tocumen Intl

Fri 10/16

2:02 pm-8:24 am

1 stop17h 22m

$579

CharlottePanama City

CLT Charlotte Douglas - PTY Panama City Tocumen Intl

CLTPTY

Charlotte Douglas

Mon 10/19

10:44 pm-1:02 pm

1 stop15h 18m

Panama City Tocumen Intl

Fri 10/23

2:02 pm-11:49 pm

1 stop8h 47m

$579

CharlottePanama City

CLT Charlotte Douglas - PTY Panama City Tocumen Intl

CLTPTY

Charlotte Douglas

Thu 11/5

6:00 am-1:59 pm

1 stop7h 59m

Panama City Tocumen Intl

Mon 11/9

3:30 pm-11:54 pm

1 stop8h 24m

$579

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Panama City?

In general, March is the cheapest month to fly from South Carolina to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $487. If you’re not able to fly to Panama City in March, then October is your next best option. Flight prices from South Carolina to Panama City during October average around $523.

Can stopping save me money on South Carolina to Panama City flights?

You could potentially save up to 1% on your flight if you consider stops on a South Carolina to Panama City flight.

Cheap South Carolina to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Panama City

Fastest flight time	7h 10m
Direct flights	None

The fastest flight from South Carolina to Panama City takes 7h 10m

There are no direct flights from South Carolina to Panama City. There are no popular flight routes from South Carolina to Panama City.

Search flight deals

Frequently asked questions about flying from South Carolina to Panama City

When did momondo last update prices for flights from South Carolina to Panama City Tocumen Intl Airport?
Prices for flights from South Carolina to Panama City Tocumen Intl Airport are refreshed on a daily basis.
How many operators does momondo search for flights from South Carolina to Panama City Tocumen Intl Airport?
As of August 2026, there are 4 operators available to choose from for flights from South Carolina to Panama City Tocumen Intl Airport.
How old do you have to be to fly from South Carolina to Panama City Tocumen Intl Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Panama City Tocumen Intl Airport.
What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?
The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from South Carolina to Panama City

Compare and see reviews for airlines that fly from South Carolina to Panama City with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $363	Free Cancellation	Rating 7.1 11,911 reviews	Search American Airlines flights
United Airlines	PriceFrom $369	Free Cancellation	Rating 7.4 10,111 reviews	Search United Airlines flights
Delta	PriceFrom $390	Free Cancellation	Rating 7.8 8,505 reviews	Search Delta flights

San Blas

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Panama City?

Finding the right flight to Panama City from South Carolina is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from South Carolina to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from South Carolina which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from South Carolina to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Panama City.

I’m not ready to book a flight from South Carolina to Panama City right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Panama City flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Sat 9/12

Sat 9/19

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Panama

Nearby airports

Airlines

Cabin classes

Other Panama destinations

Other flights from South Carolina

Complete your trip

Feeling lucky

Airports servicing Panama

Puerto Piña Bahia Pinas Airport

Bocas Del Toro Airport

Changuinola Airport

David Enrique Malek Airport

Jaque Airport

Mulatupo Airport

Puerto Obaldia Airport

Playon Chico Airport

Cheap flights from South Carolina to Panama City from $250

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Panama City departing on 8/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Find the cheapest flights from South Carolina to Panama City

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

United Airlines flights from South Carolina to Panama City

Our best United Airlines deals on South Carolina to Panama City flight tickets

GOL flights from South Carolina to Panama City

Our best GOL deals on South Carolina to Panama City flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Panama City that are best for you.

See travel insights to Panama City from

How to get the cheapest flight ticket from South Carolina to Panama City

What is the cheapest month to fly to Panama City?

Can stopping save me money on South Carolina to Panama City flights?

What is the cheapest airline that flies from South Carolina to Panama City Tocumen Intl?

What airlines fly to Panama City?

How long does it take to fly to Panama City?

Cheap South Carolina to Panama City flight deals and tips

Fastest flight time

Direct flights

Frequently asked questions about flying from South Carolina to Panama City

Best airlines flying from South Carolina to Panama City

Compare and see reviews for airlines that fly from South Carolina to Panama City with momondo

Traveling to a place near Panama City?

Why use momondo?

An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Airports servicing Panama

Fly your favorite airline to Panama City

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Panama City

List of cabin classes available on flights landing in Panama City. Availability may vary depending on flight origin and airline.

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

Fly to other destinations from South Carolina

According to popular flight searches on momondo this year

Complete your trip to Panama City

Explore popular destinations other users love

According to popular flight searches on momondo this year