How long does it take to fly to Panama City?

If you’re flying from a popular airport in South Carolina, such as Charleston or Greenville, and flying into Panama City, then you can expect flight times to average 9h 26m and 12h 38m, respectively.

What airlines fly to Panama City?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Panama City from South Carolina according to our data. American Airlines is the first choice among our users, with 47% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 3 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from South Carolina to Panama City Tocumen Intl?

United Airlines, American Airlines, and Delta are the most popular carriers operating from South Carolina to Panama City Tocumen Intl

When did momondo last update prices for flights from South Carolina to Panama City Tocumen Intl Airport?

Prices for flights from South Carolina to Panama City Tocumen Intl Airport are refreshed on a daily basis.

How many operators does momondo search for flights from South Carolina to Panama City Tocumen Intl Airport?

As of September 2026, there are 3 operators available to choose from for flights from South Carolina to Panama City Tocumen Intl Airport.

How old do you have to be to fly from South Carolina to Panama City Tocumen Intl Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Panama City Tocumen Intl Airport.

What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$278 Cheap Flights from South Carolina to Panama City in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Panama City

Round-trip

One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

7:40 am - 2:10 amCHS Charleston-PTY Panama City Tocumen Intl

18h 30m2 stops New York John F Kennedy Intl San Salvador El Salvador Intl

5:30 am - 10:22 pmPTY Panama City Tocumen Intl-CHS Charleston

16h 52m2 stops San Salvador El Salvador Intl New York John F Kennedy Intl

$582Multiple Airlines

Fri, Dec 4 - Mon, Dec 7

12:45 pm - 2:10 amCHS Charleston-PTY Panama City Tocumen Intl

13h 25m2 stops New York John F Kennedy Intl San Salvador El Salvador Intl

5:30 am - 11:55 amPTY Panama City Tocumen Intl-CHS Charleston

30h 25m2 stops San Salvador El Salvador Intl New York John F Kennedy Intl

$590Multiple Airlines

Thu, Jan 14 - Tue, Jan 19

12:45 pm - 2:10 amCHS Charleston-PTY Panama City Tocumen Intl

37h 25m2 stops New York John F Kennedy Intl San Salvador El Salvador Intl

5:30 am - 11:55 amPTY Panama City Tocumen Intl-CHS Charleston

30h 25m2 stops San Salvador El Salvador Intl New York John F Kennedy Intl

$625Multiple Airlines

Mon, Jan 25 - Fri, Jan 29

7:21 am - 2:34 pmCHS Charleston-PTY Panama City Tocumen Intl

7h 13m1 stop Miami

3:13 pm - 10:13 pmPTY Panama City Tocumen Intl-CHS Charleston

7h 00m1 stop Miami

$627American Airlines

Fri, Nov 27 - Wed, Dec 2

8:19 pm - 1:25 pmCHS Charleston-PTY Panama City Tocumen Intl

17h 06m1 stop Miami

4:55 pm - 11:59 pmPTY Panama City Tocumen Intl-CHS Charleston

7h 04m1 stop Miami

$627American Airlines

Mon, Jan 25 - Fri, Jan 29

7:00 am - 8:02 pmCHS Charleston-PTY Panama City Tocumen Intl

13h 02m1 stop Newark

8:55 am - 9:59 pmPTY Panama City Tocumen Intl-CHS Charleston

13h 04m1 stop Houston George Bush Intcntl

$627United Airlines

Wed, Dec 2 - Mon, Dec 7

10:23 am - 8:02 pmCHS Charleston-PTY Panama City Tocumen Intl

9h 39m1 stop Newark

10:00 am - 11:59 pmPTY Panama City Tocumen Intl-CHS Charleston

13h 59m1 stop Newark

$627United Airlines

Wed, Dec 2 - Mon, Dec 7

8:19 pm - 1:25 pmCHS Charleston-PTY Panama City Tocumen Intl

17h 06m1 stop Miami

4:55 pm - 1:29 pmPTY Panama City Tocumen Intl-CHS Charleston

20h 34m2 stops Miami Charlotte Douglas

$631American Airlines

Mon, Jan 25 - Fri, Jan 29

5:30 am - 1:59 pmCHS Charleston-PTY Panama City Tocumen Intl

8h 29m1 stop Atlanta Hartsfield-Jackson

3:29 pm - 11:59 pmPTY Panama City Tocumen Intl-CHS Charleston

8h 30m1 stop Atlanta Hartsfield-Jackson

$713Delta

Sun, Nov 8 - Sun, Nov 15

5:35 am - 2:04 pmCAE Columbia Metropolitan-PTY Panama City Tocumen Intl

8h 29m1 stop Atlanta Hartsfield-Jackson

3:29 pm - 11:08 amPTY Panama City Tocumen Intl-CAE Columbia Metropolitan

19h 39m1 stop Atlanta Hartsfield-Jackson

$750Delta

Wed, Nov 25 - Mon, Nov 30

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American Airlines flights from South Carolina to Panama City

Our best American Airlines deals on South Carolina to Panama City flight tickets

American Airlines

Nov 27

CHS7:21 amCharleston

7h 13m

1 stop

PTY2:34 pmPanama City Tocumen Intl

Dec 2

PTY3:13 pmPanama City Tocumen Intl

6h 45m

1 stop

CHS9:58 pmCharleston

$627

American Airlines

Jan 5

GSP5:30 amGreenville

8h 21m

1 stop

PTY1:51 pmPanama City Tocumen Intl

Feb 5

PTY4:55 pmPanama City Tocumen Intl

7h 04m

1 stop

GSP11:59 pmGreenville

$645

American Airlines

Jan 5

GSP5:30 amGreenville

8h 21m

1 stop

PTY1:51 pmPanama City Tocumen Intl

Feb 5

PTY4:55 pmPanama City Tocumen Intl

17h 27m

2 stops

GSP10:22 amGreenville

$649

Delta flights from South Carolina to Panama City

Our best Delta deals on South Carolina to Panama City flight tickets

Delta

Nov 23

GSP7:19 pmGreenville

18h 43m

1 stop

PTY2:02 pmPanama City Tocumen Intl

Nov 26

PTY3:29 pmPanama City Tocumen Intl

6h 43m

1 stop

GSP10:12 pmGreenville

$664

Delta

Nov 18

GSP5:40 amGreenville

8h 22m

1 stop

PTY2:02 pmPanama City Tocumen Intl

Nov 26

PTY3:29 pmPanama City Tocumen Intl

6h 43m

1 stop

GSP10:12 pmGreenville

$700

Delta

Nov 8

CHS5:30 amCharleston

8h 29m

1 stop

PTY1:59 pmPanama City Tocumen Intl

Nov 15

PTY3:29 pmPanama City Tocumen Intl

8h 30m

1 stop

CHS11:59 pmCharleston

$713

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Fri 12/4

7:40 am-2:10 am

2 stops18h 30m

Panama City Tocumen Intl

Mon 12/7

5:30 am-10:22 pm

2 stops16h 52m

$582

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Thu 1/14

12:45 pm-2:10 am

2 stops13h 25m

Panama City Tocumen Intl

Tue 1/19

5:30 am-11:55 am

2 stops30h 25m

$590

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Mon 1/25

12:45 pm-2:10 am

2 stops37h 25m

Panama City Tocumen Intl

Fri 1/29

5:30 am-11:55 am

2 stops30h 25m

$625

Quickest round-trip

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Fri 11/27

7:21 am-2:34 pm

1 stop7h 13m

Panama City Tocumen Intl

Wed 12/2

3:13 pm-10:13 pm

1 stop7h 00m

$627

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Mon 1/25

8:19 pm-1:25 pm

1 stop17h 06m

Panama City Tocumen Intl

Fri 1/29

4:55 pm-11:59 pm

1 stop7h 04m

$627

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Wed 12/2

7:00 am-8:02 pm

1 stop13h 02m

Panama City Tocumen Intl

Mon 12/7

8:55 am-9:59 pm

1 stop13h 04m

$627

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Wed 12/2

10:23 am-8:02 pm

1 stop9h 39m

Panama City Tocumen Intl

Mon 12/7

10:00 am-11:59 pm

1 stop13h 59m

$627

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Mon 1/25

8:19 pm-1:25 pm

1 stop17h 06m

Panama City Tocumen Intl

Fri 1/29

4:55 pm-1:29 pm

2 stops20h 34m

$631

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Sun 11/8

5:30 am-1:59 pm

1 stop8h 29m

Panama City Tocumen Intl

Sun 11/15

3:29 pm-11:59 pm

1 stop8h 30m

$713

ColumbiaPanama City

CAE Columbia Metropolitan - PTY Panama City Tocumen Intl

CAEPTY

Columbia Metropolitan

Wed 11/25

5:35 am-2:04 pm

1 stop8h 29m

Panama City Tocumen Intl

Mon 11/30

3:29 pm-11:08 am

1 stop19h 39m

$750

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Panama City?

In general, March is the cheapest month to fly from South Carolina to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $487. If you’re not able to fly to Panama City in March, then February is your next best option. Flight prices from South Carolina to Panama City during February average around $570.

Can stopping save me money on South Carolina to Panama City flights?

You could potentially save up to 1% on your flight if you consider stops on a South Carolina to Panama City flight.

Cheap South Carolina to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Panama City

Best Price Found	$278
Fastest flight time	6h 18m
Direct flights	None

The best one-way flight to Panama City from South Carolina in the past 72 hours is $278. The best round-trip flight deal from South Carolina to Panama City found on momondo in the last 72 hours is $582.

The fastest flight from South Carolina to Panama City takes 6h 18m

There are no direct flights from South Carolina to Panama City. There are no popular flight routes from South Carolina to Panama City.

Search flight deals

Frequently asked questions about flying from South Carolina to Panama City

When did momondo last update prices for flights from South Carolina to Panama City Tocumen Intl Airport?
Prices for flights from South Carolina to Panama City Tocumen Intl Airport are refreshed on a daily basis.
How many operators does momondo search for flights from South Carolina to Panama City Tocumen Intl Airport?
As of September 2026, there are 3 operators available to choose from for flights from South Carolina to Panama City Tocumen Intl Airport.
How old do you have to be to fly from South Carolina to Panama City Tocumen Intl Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Panama City Tocumen Intl Airport.
What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?
The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from South Carolina to Panama City

Compare and see reviews for airlines that fly from South Carolina to Panama City with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $299	Free Cancellation	Rating 7.8 8,605 reviews	Search Delta flights
United Airlines	PriceFrom $369	Free Cancellation	Rating 7.4 10,242 reviews	Search United Airlines flights
American Airlines	PriceFrom $399	Free Cancellation	Rating 7.0 12,099 reviews	Search American Airlines flights

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Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Panama City?

Finding the right flight to Panama City from South Carolina is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from South Carolina to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from South Carolina which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from South Carolina to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Panama City.

I’m not ready to book a flight from South Carolina to Panama City right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Panama City flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Airports servicing Panama

Puerto Piña Bahia Pinas Airport

Bocas Del Toro Airport

Changuinola Airport

David Enrique Malek Airport

Jaque Airport

Mulatupo Airport

Puerto Obaldia Airport

Playon Chico Airport

Cheap flights from South Carolina to Panama City from $278

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Panama City departing on 1/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from South Carolina to Panama City

Our best American Airlines deals on South Carolina to Panama City flight tickets

Delta flights from South Carolina to Panama City

Our best Delta deals on South Carolina to Panama City flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Panama City that are best for you.

See travel insights to Panama City from

How to get the cheapest flight ticket from South Carolina to Panama City

What is the cheapest month to fly to Panama City?

Can stopping save me money on South Carolina to Panama City flights?

What is the cheapest airline that flies from South Carolina to Panama City Tocumen Intl?

What airlines fly to Panama City?

How long does it take to fly to Panama City?

Cheap South Carolina to Panama City flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from South Carolina to Panama City

Best airlines flying from South Carolina to Panama City

Compare and see reviews for airlines that fly from South Carolina to Panama City with momondo

Traveling to a place near Panama City?

Why use momondo?

An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Airports servicing Panama

Fly your favorite airline to Panama City

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Panama City

List of cabin classes available on flights landing in Panama City. Availability may vary depending on flight origin and airline.

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