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Cheap flights from South Carolina to Guayaquil from $119

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Guayaquil departing on 3/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Carolina to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
3:15 pm - 11:04 pm
CLT
-
GYE
8h 49m
1 stop
Spirit Airlines Logo
11:59 pm - 10:17 am
GYE
-
CLT
9h 18m
1 stop
$272Spirit Airlines
Tue, Apr 28 - Wed, May 6
Spirit Airlines Logo
1:20 pm - 11:04 pm
CLT
-
GYE
10h 44m
1 stop
Spirit Airlines Logo
11:59 pm - 10:17 am
GYE
-
CLT
9h 18m
1 stop
$290Spirit Airlines
Sat, Apr 11 - Sat, Apr 18
Spirit Airlines Logo
8:55 am - 11:04 pm
CLT
-
GYE
15h 09m
1 stop
Spirit Airlines Logo
11:59 pm - 10:14 am
GYE
-
CLT
9h 15m
2 stops
$296Spirit Airlines
Tue, Apr 28 - Tue, May 5
American Airlines Logo
8:09 pm - 1:31 pm
CHS
-
GYE
18h 22m
1 stop
American Airlines Logo
2:31 pm - 10:07 am
GYE
-
CHS
18h 36m
2 stops
$309American Airlines
Wed, May 20 - Sat, May 30
Multiple Airlines Logo
4:36 pm - 11:04 pm
CLT
-
GYE
31h 28m
1 stop
Multiple Airlines Logo
11:59 pm - 8:16 am
GYE
-
CLT
31h 17m
1 stop
$315Multiple Airlines
Sat, Apr 25 - Sat, May 30
Multiple Airlines Logo
9:58 am - 11:04 pm
MYR
-
GYE
14h 06m
1 stop
Multiple Airlines Logo
11:59 pm - 4:31 pm
GYE
-
MYR
15h 32m
1 stop
$363Multiple Airlines
Mon, Apr 13 - Mon, Apr 20
JetBlue Logo
8:08 pm - 2:50 pm
CHS
-
GYE
19h 42m
1 stop
JetBlue Logo
12:59 pm - 9:49 am
GYE
-
CHS
19h 50m
1 stop
$378JetBlue
Wed, May 20 - Sat, May 30
JetBlue Logo
10:39 am - 2:50 pm
CHS
-
GYE
29h 11m
1 stop
JetBlue Logo
12:59 pm - 9:49 am
GYE
-
CHS
19h 50m
1 stop
$393JetBlue
Tue, May 26 - Fri, Jun 5
American Airlines Logo
9:14 am - 9:12 pm
MYR
-
GYE
12h 58m
2 stops
American Airlines Logo
2:31 pm - 9:45 am
GYE
-
MYR
18h 14m
2 stops
$648American Airlines
Mon, Apr 13 - Mon, Apr 20
LATAM Airlines Logo
10:23 am - 7:51 am
MYR
-
GYE
22h 28m
2 stops
LATAM Airlines Logo
2:58 pm - 12:57 pm
GYE
-
MYR
20h 59m
2 stops
$834LATAM Airlines
Thu, Apr 9 - Mon, Apr 13

Spirit Airlines flights from South Carolina to Guayaquil

Our best Spirit Airlines deals on South Carolina to Guayaquil flight tickets
Spirit Airlines
Apr 11
CLT1:20 pmCharlotte Douglas
10h 44m
1 stop
GYE11:04 pmGuayaquil Jose Joaquin de Olmedo
Apr 18
GYE11:59 pmGuayaquil Jose Joaquin de Olmedo
9h 18m
1 stop
CLT10:17 amCharlotte Douglas
$290
Spirit Airlines
Apr 15
CLT7:00 amCharlotte Douglas
17h 04m
1 stop
GYE11:04 pmGuayaquil Jose Joaquin de Olmedo
Apr 21
GYE11:59 pmGuayaquil Jose Joaquin de Olmedo
8h 11m
1 stop
CLT9:10 amCharlotte Douglas
$301
Spirit Airlines
Mar 20
CLT6:00 amCharlotte Douglas
18h 04m
1 stop
GYE11:04 pmGuayaquil Jose Joaquin de Olmedo
Mar 23
GYE11:59 pmGuayaquil Jose Joaquin de Olmedo
19h 18m
1 stop
CLT8:17 pmCharlotte Douglas
$308

LATAM Airlines flights from South Carolina to Guayaquil

Our best LATAM Airlines deals on South Carolina to Guayaquil flight tickets
LATAM Airlines
Apr 9
MYR10:23 amMyrtle Beach Intl
22h 28m
2 stops
GYE7:51 amGuayaquil Jose Joaquin de Olmedo
Apr 13
GYE2:58 pmGuayaquil Jose Joaquin de Olmedo
20h 59m
2 stops
MYR12:57 pmMyrtle Beach Intl
$834
LATAM Airlines
Mar 3
CLT9:54 amCharlotte Douglas
15h 46m
2 stops
GYE1:40 amGuayaquil Jose Joaquin de Olmedo
Mar 4
GYE9:03 pmGuayaquil Jose Joaquin de Olmedo
13h 57m
2 stops
CLT11:00 amCharlotte Douglas
$1,183
LATAM Airlines
Mar 3
CLT9:54 amCharlotte Douglas
15h 46m
2 stops
GYE1:40 amGuayaquil Jose Joaquin de Olmedo
Mar 4
GYE9:03 pmGuayaquil Jose Joaquin de Olmedo
21h 09m
2 stops
CLT6:12 pmCharlotte Douglas
$1,339

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 1, 2026.
Use the filters below to find and compare flights from South Carolina to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Tue 4/28

3:15 pm-11:04 pm

1 stop8h 49m

Guayaquil Jose Joaquin de Olmedo

Wed 5/6

11:59 pm-10:17 am

1 stop9h 18m

$272

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Sat 4/11

1:20 pm-11:04 pm

1 stop10h 44m

Guayaquil Jose Joaquin de Olmedo

Sat 4/18

11:59 pm-10:17 am

1 stop9h 18m

$290

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Tue 4/28

8:55 am-11:04 pm

1 stop15h 09m

Guayaquil Jose Joaquin de Olmedo

Tue 5/5

11:59 pm-10:14 am

2 stops9h 15m

$296

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Wed 5/20

8:09 pm-1:31 pm

1 stop18h 22m

Guayaquil Jose Joaquin de Olmedo

Sat 5/30

2:31 pm-10:07 am

2 stops18h 36m

$309

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Sat 4/25

4:36 pm-11:04 pm

1 stop31h 28m

Guayaquil Jose Joaquin de Olmedo

Sat 5/30

11:59 pm-8:16 am

1 stop31h 17m

$315

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

Mon 4/13

9:58 am-11:04 pm

1 stop14h 06m

Guayaquil Jose Joaquin de Olmedo

Mon 4/20

11:59 pm-4:31 pm

1 stop15h 32m

$363

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Wed 5/20

8:08 pm-2:50 pm

1 stop19h 42m

Guayaquil Jose Joaquin de Olmedo

Sat 5/30

12:59 pm-9:49 am

1 stop19h 50m

$378

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Tue 5/26

10:39 am-2:50 pm

1 stop29h 11m

Guayaquil Jose Joaquin de Olmedo

Fri 6/5

12:59 pm-9:49 am

1 stop19h 50m

$393

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

Mon 4/13

9:14 am-9:12 pm

2 stops12h 58m

Guayaquil Jose Joaquin de Olmedo

Mon 4/20

2:31 pm-9:45 am

2 stops18h 14m

$648

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

Thu 4/9

10:23 am-7:51 am

2 stops22h 28m

Guayaquil Jose Joaquin de Olmedo

Mon 4/13

2:58 pm-12:57 pm

2 stops20h 59m

$834

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from South Carolina to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on South Carolina to Guayaquil flights?

You could potentially save up to 37% on your flight if you consider stops on a South Carolina to Guayaquil flight.

Cheap South Carolina to Guayaquil flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Guayaquil

Fastest flight time

10h 44m

Direct flights

None
The fastest flight from South Carolina to Guayaquil takes 10h 44m
There are no direct flights from South Carolina to Guayaquil. There are no popular flight routes from South Carolina to Guayaquil.
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport refresh daily.

  • How many operators does momondo search for flights from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The travel and health documents required for your trip to Guayaquil Jose Joaquin de Olmedo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guayaquil Jose Joaquin de Olmedo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from South Carolina to Guayaquil

Compare and see reviews for airlines that fly from South Carolina to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $813Free CancellationRating
7.1
11,370 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Guayaquil?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Guayaquil from South Carolina.

Can I find flights from South Carolina to Guayaquil with flexible booking policies on momondo?

momondo does allow users to show only those flights to Guayaquil from South Carolina which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from South Carolina to Guayaquil?

Once all potential South Carolina to Guayaquil flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from South Carolina to Guayaquil right now. Can momondo alert me if prices change?

Price alerts on flights to Guayaquil from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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