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Cheap flights from South Carolina to Guayaquil from $120

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Guayaquil departing on 12/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from South Carolina to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
7:00 am - 12:21 amCLT-GYE
17h 21m1 stop
Spirit Airlines Logo
1:26 am - 10:58 amGYE-CLT
9h 32m1 stop
$286Spirit Airlines
Find Deal
Sun, Jan 25 - Tue, Jan 27
Spirit Airlines Logo
7:00 am - 12:21 amCLT-GYE
17h 21m1 stop
Spirit Airlines Logo
12:59 am - 6:02 pmGYE-CLT
17h 03m1 stop
$291Spirit Airlines
Find Deal
Wed, Feb 4 - Wed, Feb 18
Spirit Airlines Logo
1:24 pm - 12:21 amCLT-GYE
10h 57m1 stop
Spirit Airlines Logo
12:59 am - 6:02 pmGYE-CLT
17h 03m1 stop
$293Spirit Airlines
Find Deal
Thu, Feb 5 - Wed, Feb 18
Spirit Airlines Logo
11:12 am - 12:21 amCLT-GYE
13h 09m2 stops
Spirit Airlines Logo
12:59 am - 6:02 pmGYE-CLT
17h 03m1 stop
$297Spirit Airlines
Find Deal
Thu, Feb 5 - Wed, Feb 18
Spirit Airlines Logo
7:00 am - 12:21 amCLT-GYE
17h 21m1 stop
Spirit Airlines Logo
1:26 am - 6:01 pmGYE-CLT
16h 35m1 stop
$304Spirit Airlines
Find Deal
Wed, Feb 4 - Sat, Feb 7
American Airlines Logo
6:10 am - 11:22 pmCHS-GYE
17h 12m2 stops
American Airlines Logo
7:15 am - 3:27 pmGYE-CHS
32h 12m2 stops
$420American Airlines
Find Deal
Mon, Jan 26 - Wed, Jan 28
Delta Logo
5:53 pm - 7:20 amCHS-GYE
13h 27m1 stop
Delta Logo
4:30 pm - 11:20 amGYE-CHS
18h 50m1 stop
$528Delta
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Mon, Jan 26 - Wed, Jan 28
Delta Logo
10:31 am - 7:20 amCHS-GYE
20h 49m2 stops
Delta Logo
4:30 pm - 11:20 amGYE-CHS
18h 50m1 stop
$533Delta
Find Deal
Mon, Jan 26 - Wed, Jan 28
JetBlue Logo
7:05 pm - 4:00 amCHS-GYE
9h 55m1 stop
JetBlue Logo
6:00 am - 11:07 pmGYE-CHS
16h 07m1 stop
$562JetBlue
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Fri, Apr 3 - Mon, Apr 6
American Airlines Logo
5:51 am - 1:33 pmCHS-GYE
8h 42m1 stop
American Airlines Logo
2:33 pm - 3:25 pmGYE-CHS
23h 52m2 stops
$596American Airlines
Find Deal
Fri, Apr 3 - Mon, Apr 6

JetBlue flights from South Carolina to Guayaquil

Our best JetBlue deals on South Carolina to Guayaquil flight tickets
JetBlue
Apr 3
CHS7:05 pmCharleston
9h 55m
1 stop
GYE4:00 amGuayaquil Jose Joaquin de Olmedo
Apr 6
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
16h 07m
1 stop
CHS11:07 pmCharleston
$562
Find similar
JetBlue
Dec 24
CHS7:03 pmCharleston
20h 07m
1 stop
GYE3:10 pmGuayaquil Jose Joaquin de Olmedo
Jan 2
GYE7:30 amGuayaquil Jose Joaquin de Olmedo
11h 53m
1 stop
CHS7:23 pmCharleston
$1,256
Find similar

Spirit Airlines flights from South Carolina to Guayaquil

Our best Spirit Airlines deals on South Carolina to Guayaquil flight tickets
Spirit Airlines
Jan 25
CLT7:00 amCharlotte Douglas
17h 21m
1 stop
GYE12:21 amGuayaquil Jose Joaquin de Olmedo
Jan 27
GYE1:26 amGuayaquil Jose Joaquin de Olmedo
9h 32m
1 stop
CLT10:58 amCharlotte Douglas
$286
Find similar
Spirit Airlines
Feb 4
CLT7:00 amCharlotte Douglas
17h 21m
1 stop
GYE12:21 amGuayaquil Jose Joaquin de Olmedo
Feb 18
GYE12:59 amGuayaquil Jose Joaquin de Olmedo
17h 03m
1 stop
CLT6:02 pmCharlotte Douglas
$291
Find similar
Spirit Airlines
Feb 5
CLT1:24 pmCharlotte Douglas
10h 57m
1 stop
GYE12:21 amGuayaquil Jose Joaquin de Olmedo
Feb 18
GYE12:59 amGuayaquil Jose Joaquin de Olmedo
17h 03m
1 stop
CLT6:02 pmCharlotte Douglas
$293
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 21, 2025.
Use the filters below to find and compare flights from South Carolina to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Sun 1/25

7:00 am-12:21 am

1 stop17h 21m

Guayaquil Jose Joaquin de Olmedo

Tue 1/27

1:26 am-10:58 am

1 stop9h 32m

$286

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Wed 2/4

7:00 am-12:21 am

1 stop17h 21m

Guayaquil Jose Joaquin de Olmedo

Wed 2/18

12:59 am-6:02 pm

1 stop17h 03m

$291

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Thu 2/5

1:24 pm-12:21 am

1 stop10h 57m

Guayaquil Jose Joaquin de Olmedo

Wed 2/18

12:59 am-6:02 pm

1 stop17h 03m

$293

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Thu 2/5

11:12 am-12:21 am

2 stops13h 09m

Guayaquil Jose Joaquin de Olmedo

Wed 2/18

12:59 am-6:02 pm

1 stop17h 03m

$297

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Wed 2/4

7:00 am-12:21 am

1 stop17h 21m

Guayaquil Jose Joaquin de Olmedo

Sat 2/7

1:26 am-6:01 pm

1 stop16h 35m

$304

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Mon 1/26

6:10 am-11:22 pm

2 stops17h 12m

Guayaquil Jose Joaquin de Olmedo

Wed 1/28

7:15 am-3:27 pm

2 stops32h 12m

$420

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Mon 1/26

5:53 pm-7:20 am

1 stop13h 27m

Guayaquil Jose Joaquin de Olmedo

Wed 1/28

4:30 pm-11:20 am

1 stop18h 50m

$528

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Mon 1/26

10:31 am-7:20 am

2 stops20h 49m

Guayaquil Jose Joaquin de Olmedo

Wed 1/28

4:30 pm-11:20 am

1 stop18h 50m

$533

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Fri 4/3

7:05 pm-4:00 am

1 stop9h 55m

Guayaquil Jose Joaquin de Olmedo

Mon 4/6

6:00 am-11:07 pm

1 stop16h 07m

$562

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Fri 4/3

5:51 am-1:33 pm

1 stop8h 42m

Guayaquil Jose Joaquin de Olmedo

Mon 4/6

2:33 pm-3:25 pm

2 stops23h 52m

$596

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from South Carolina to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Guayaquil?

The cheapest day to depart from South Carolina to Guayaquil is on a Saturday. Travelers who choose to depart for Guayaquil on a Saturday will often find tickets for as low as $516. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Guayaquil on Friday is $657.

What is the cheapest time of day to depart on your flight to Guayaquil?

The cheapest time of day to fly to Guayaquil is in the morning when flights can be purchased for as low as $516. Flights to Guayaquil are more costly in the afternoon, with an average ticket price of $624. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

Can stopping save me money on South Carolina to Guayaquil flights?

You could potentially save up to 2% on your flight if you consider stops on a South Carolina to Guayaquil flight.

Cheap South Carolina to Guayaquil flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Guayaquil

Direct flights

None
There are no direct flights from South Carolina to Guayaquil. There are no popular flight routes from South Carolina to Guayaquil.
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  • When did momondo last update prices for flights from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport refresh daily.

  • How many operators does momondo search for flights from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The travel and health documents required for your trip to Guayaquil Jose Joaquin de Olmedo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guayaquil Jose Joaquin de Olmedo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from South Carolina to Guayaquil

Compare and see reviews for airlines that fly from South Carolina to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $519Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Guayaquil?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Guayaquil from South Carolina.

Can I find flights from South Carolina to Guayaquil with flexible booking policies on momondo?

momondo does allow users to show only those flights to Guayaquil from South Carolina which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from South Carolina to Guayaquil?

Once all potential South Carolina to Guayaquil flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from South Carolina to Guayaquil right now. Can momondo alert me if prices change?

Price alerts on flights to Guayaquil from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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