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Cheap flights from South Carolina to Guayaquil from $140

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Guayaquil departing on 5/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from South Carolina to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
9:07 pm - 11:04 pm
CLT
-
GYE
26h 57m
1 stop
Spirit Airlines Logo
11:59 pm - 8:02 pm
GYE
-
CLT
19h 03m
1 stop
$351Spirit Airlines
Sat, May 9 - Thu, May 14
Multiple Airlines Logo
9:07 pm - 8:55 am
CLT
-
GYE
36h 48m
2 stops
Multiple Airlines Logo
11:59 pm - 8:02 pm
GYE
-
CLT
19h 03m
1 stop
$375Multiple Airlines
Sat, May 9 - Thu, May 14
Spirit Airlines Logo
9:07 pm - 11:04 pm
CLT
-
GYE
26h 57m
1 stop
Spirit Airlines Logo
11:59 pm - 11:40 pm
GYE
-
CLT
22h 41m
1 stop
$385Spirit Airlines
Sat, May 9 - Thu, May 14
Multiple Airlines Logo
9:07 pm - 11:04 pm
CLT
-
GYE
26h 57m
1 stop
Multiple Airlines Logo
6:28 pm - 11:43 am
GYE
-
CLT
16h 15m
2 stops
$389Multiple Airlines
Sat, May 9 - Thu, May 14
JetBlue Logo
8:16 pm - 11:39 am
CHS
-
GYE
16h 23m
1 stop
JetBlue Logo
4:15 pm - 8:39 am
GYE
-
CHS
15h 24m
1 stop
$442JetBlue
Fri, May 29 - Fri, Jun 5
American Airlines Logo
6:00 am - 10:37 pm
CHS
-
GYE
17h 37m
2 stops
American Airlines Logo
2:31 pm - 10:20 am
GYE
-
CHS
18h 49m
2 stops
$507American Airlines
Fri, May 29 - Fri, Jun 5
United Airlines Logo
6:35 am - 11:36 pm
CHS
-
GYE
18h 01m
2 stops
United Airlines Logo
12:22 pm - 9:59 pm
GYE
-
CHS
32h 37m
2 stops
$855United Airlines
Thu, May 7 - Sun, May 10
United Airlines Logo
11:15 am - 5:29 pm
CHS
-
GYE
31h 14m
2 stops
United Airlines Logo
12:22 pm - 9:10 am
GYE
-
CHS
19h 48m
2 stops
$890United Airlines
Thu, May 7 - Sun, May 10
LATAM Airlines Logo
10:26 am - 7:49 am
MYR
-
GYE
22h 23m
2 stops
LATAM Airlines Logo
8:45 pm - 6:08 pm
GYE
-
MYR
20h 23m
2 stops
$1,176LATAM Airlines
Fri, May 1 - Sun, May 3
LATAM Airlines Logo
6:00 am - 7:49 am
MYR
-
GYE
26h 49m
2 stops
LATAM Airlines Logo
4:20 pm - 6:08 pm
GYE
-
MYR
24h 48m
2 stops
$1,306LATAM Airlines
Fri, May 1 - Sun, May 3

LATAM Airlines flights from South Carolina to Guayaquil

Our best LATAM Airlines deals on South Carolina to Guayaquil flight tickets
LATAM Airlines
Apr 28
CLT9:55 amCharlotte Douglas
23h 44m
2 stops
GYE8:39 amGuayaquil Jose Joaquin de Olmedo
May 5
GYE9:05 amGuayaquil Jose Joaquin de Olmedo
22h 41m
2 stops
CLT8:46 amCharlotte Douglas
$1,133
LATAM Airlines
May 1
MYR10:26 amMyrtle Beach Intl
22h 23m
2 stops
GYE7:49 amGuayaquil Jose Joaquin de Olmedo
May 3
GYE8:45 pmGuayaquil Jose Joaquin de Olmedo
20h 23m
2 stops
MYR6:08 pmMyrtle Beach Intl
$1,176
LATAM Airlines
May 1
MYR6:00 amMyrtle Beach Intl
26h 49m
2 stops
GYE7:49 amGuayaquil Jose Joaquin de Olmedo
May 3
GYE4:20 pmGuayaquil Jose Joaquin de Olmedo
24h 48m
2 stops
MYR6:08 pmMyrtle Beach Intl
$1,306

Spirit Airlines flights from South Carolina to Guayaquil

Our best Spirit Airlines deals on South Carolina to Guayaquil flight tickets
Spirit Airlines
May 9
CLT9:07 pmCharlotte Douglas
26h 57m
1 stop
GYE11:04 pmGuayaquil Jose Joaquin de Olmedo
May 14
GYE11:59 pmGuayaquil Jose Joaquin de Olmedo
19h 03m
1 stop
CLT8:02 pmCharlotte Douglas
$351
Spirit Airlines
May 9
CLT9:07 pmCharlotte Douglas
26h 57m
1 stop
GYE11:04 pmGuayaquil Jose Joaquin de Olmedo
May 14
GYE11:59 pmGuayaquil Jose Joaquin de Olmedo
22h 41m
1 stop
CLT11:40 pmCharlotte Douglas
$385
Spirit Airlines
May 28
CLT6:00 amCharlotte Douglas
18h 04m
1 stop
GYE11:04 pmGuayaquil Jose Joaquin de Olmedo
May 31
GYE11:59 pmGuayaquil Jose Joaquin de Olmedo
19h 03m
1 stop
CLT8:02 pmCharlotte Douglas
$421

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 19, 2026.
Use the filters below to find and compare flights from South Carolina to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Sat 5/9

9:07 pm-11:04 pm

1 stop26h 57m

Guayaquil Jose Joaquin de Olmedo

Thu 5/14

11:59 pm-8:02 pm

1 stop19h 03m

$351

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Sat 5/9

9:07 pm-8:55 am

2 stops36h 48m

Guayaquil Jose Joaquin de Olmedo

Thu 5/14

11:59 pm-8:02 pm

1 stop19h 03m

$375

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Sat 5/9

9:07 pm-11:04 pm

1 stop26h 57m

Guayaquil Jose Joaquin de Olmedo

Thu 5/14

11:59 pm-11:40 pm

1 stop22h 41m

$385

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Sat 5/9

9:07 pm-11:04 pm

1 stop26h 57m

Guayaquil Jose Joaquin de Olmedo

Thu 5/14

6:28 pm-11:43 am

2 stops16h 15m

$389
Quickest round-trip

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Fri 5/29

8:16 pm-11:39 am

1 stop16h 23m

Guayaquil Jose Joaquin de Olmedo

Fri 6/5

4:15 pm-8:39 am

1 stop15h 24m

$442

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Fri 5/29

6:00 am-10:37 pm

2 stops17h 37m

Guayaquil Jose Joaquin de Olmedo

Fri 6/5

2:31 pm-10:20 am

2 stops18h 49m

$507

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Thu 5/7

6:35 am-11:36 pm

2 stops18h 01m

Guayaquil Jose Joaquin de Olmedo

Sun 5/10

12:22 pm-9:59 pm

2 stops32h 37m

$855

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Thu 5/7

11:15 am-5:29 pm

2 stops31h 14m

Guayaquil Jose Joaquin de Olmedo

Sun 5/10

12:22 pm-9:10 am

2 stops19h 48m

$890

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

Fri 5/1

10:26 am-7:49 am

2 stops22h 23m

Guayaquil Jose Joaquin de Olmedo

Sun 5/3

8:45 pm-6:08 pm

2 stops20h 23m

$1,176

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

Fri 5/1

6:00 am-7:49 am

2 stops26h 49m

Guayaquil Jose Joaquin de Olmedo

Sun 5/3

4:20 pm-6:08 pm

2 stops24h 48m

$1,306

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Guayaquil from

How to get the cheapest flight ticket from South Carolina to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on South Carolina to Guayaquil flights?

You could potentially save up to 9% on your flight if you consider stops on a South Carolina to Guayaquil flight.

Cheap South Carolina to Guayaquil flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Guayaquil

Fastest flight time

6h 58m

Direct flights

None
The fastest flight from South Carolina to Guayaquil takes 6h 58m
There are no direct flights from South Carolina to Guayaquil. There are no popular flight routes from South Carolina to Guayaquil.
Search flight deals

Frequently asked questions about flying from South Carolina to Guayaquil

  • When did momondo last update prices for flights from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport refresh daily.

  • How many operators does momondo search for flights from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The travel and health documents required for your trip to Guayaquil Jose Joaquin de Olmedo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guayaquil Jose Joaquin de Olmedo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from South Carolina to Guayaquil

Compare and see reviews for airlines that fly from South Carolina to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $714Free CancellationRating
7.1
11,619 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Guayaquil?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Guayaquil from South Carolina.

Can I find flights from South Carolina to Guayaquil with flexible booking policies on momondo?

momondo does allow users to show only those flights to Guayaquil from South Carolina which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from South Carolina to Guayaquil?

Once all potential South Carolina to Guayaquil flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from South Carolina to Guayaquil right now. Can momondo alert me if prices change?

Price alerts on flights to Guayaquil from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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