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Cheap flights from South Carolina to Guayaquil from $178

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Guayaquil departing on 10/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 10:45 pm
CLT
-
GYE
17h 45m
1 stop
American Airlines Logo
6:00 am - 9:14 pm
GYE
-
CLT
14h 14m
1 stop
$409American Airlines
Wed, Oct 7 - Sun, Oct 11
American Airlines Logo
11:00 am - 10:45 pm
CLT
-
GYE
12h 45m
2 stops
American Airlines Logo
6:00 am - 9:14 pm
GYE
-
CLT
14h 14m
1 stop
$414American Airlines
Wed, Oct 7 - Sun, Oct 11
American Airlines Logo
9:08 am - 10:45 pm
CLT
-
GYE
14h 37m
1 stop
American Airlines Logo
2:29 pm - 9:57 am
GYE
-
CLT
18h 28m
1 stop
$416American Airlines
Wed, Oct 14 - Sun, Oct 25
Delta Logo
5:00 pm - 7:14 am
CLT
-
GYE
15h 14m
1 stop
Delta Logo
4:19 pm - 8:19 am
GYE
-
CLT
15h 00m
1 stop
$444Delta
Tue, Oct 6 - Mon, Oct 12
Delta Logo
2:17 pm - 7:14 am
CLT
-
GYE
17h 57m
2 stops
Delta Logo
4:19 pm - 4:05 pm
GYE
-
CLT
22h 46m
2 stops
$448Delta
Tue, Oct 6 - Mon, Oct 12
Multiple Airlines Logo
8:14 pm - 10:40 am
CHS
-
GYE
15h 26m
1 stop
Multiple Airlines Logo
4:05 pm - 10:10 am
GYE
-
CHS
17h 05m
1 stop
$593Multiple Airlines
Thu, Aug 27 - Sat, Sep 5
Multiple Airlines Logo
8:14 pm - 2:35 pm
CHS
-
GYE
19h 21m
2 stops
Multiple Airlines Logo
4:05 pm - 10:10 am
GYE
-
CHS
17h 05m
1 stop
$632Multiple Airlines
Thu, Aug 27 - Sat, Sep 5
JetBlue Logo
5:27 pm - 3:22 pm
CHS
-
GYE
22h 55m
1 stop
JetBlue Logo
1:25 pm - 4:31 pm
GYE
-
CHS
26h 06m
1 stop
$660JetBlue
Thu, Sep 3 - Mon, Sep 7
United Airlines Logo
10:10 am - 11:37 pm
MYR
-
GYE
14h 27m
2 stops
United Airlines Logo
8:28 am - 9:55 am
GYE
-
MYR
48h 27m
2 stops
$925United Airlines
Wed, Sep 23 - Fri, Sep 25
United Airlines Logo
10:10 am - 5:30 pm
MYR
-
GYE
32h 20m
2 stops
United Airlines Logo
12:22 pm - 3:16 pm
GYE
-
MYR
25h 54m
2 stops
$1,163United Airlines
Wed, Sep 23 - Fri, Sep 25

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Delta flights from South Carolina to Guayaquil

Our best Delta deals on South Carolina to Guayaquil flight tickets
Delta
Oct 6
CLT11:58 amCharlotte Douglas
20h 16m
1 stop
GYE7:14 amGuayaquil Jose Joaquin de Olmedo
Oct 13
GYE4:19 pmGuayaquil Jose Joaquin de Olmedo
20h 20m
1 stop
CLT1:39 pmCharlotte Douglas
$444
Delta
Oct 6
CLT2:17 pmCharlotte Douglas
17h 57m
2 stops
GYE7:14 amGuayaquil Jose Joaquin de Olmedo
Oct 13
GYE4:19 pmGuayaquil Jose Joaquin de Olmedo
22h 46m
2 stops
CLT4:05 pmCharlotte Douglas
$448
Delta
Oct 4
CLT7:00 amCharlotte Douglas
25h 14m
1 stop
GYE7:14 amGuayaquil Jose Joaquin de Olmedo
Oct 13
GYE4:19 pmGuayaquil Jose Joaquin de Olmedo
20h 20m
1 stop
CLT1:39 pmCharlotte Douglas
$451

American Airlines flights from South Carolina to Guayaquil

Our best American Airlines deals on South Carolina to Guayaquil flight tickets
American Airlines
Oct 7
CLT10:44 pmCharlotte Douglas
15h 45m
1 stop
GYE1:29 pmGuayaquil Jose Joaquin de Olmedo
Oct 11
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
14h 14m
1 stop
CLT9:14 pmCharlotte Douglas
$409
American Airlines
Oct 7
CLT11:00 amCharlotte Douglas
12h 45m
2 stops
GYE10:45 pmGuayaquil Jose Joaquin de Olmedo
Oct 11
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
14h 14m
1 stop
CLT9:14 pmCharlotte Douglas
$414
American Airlines
Oct 14
CLT9:08 amCharlotte Douglas
14h 37m
1 stop
GYE10:45 pmGuayaquil Jose Joaquin de Olmedo
Oct 25
GYE2:29 pmGuayaquil Jose Joaquin de Olmedo
18h 28m
1 stop
CLT9:57 amCharlotte Douglas
$416

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 23, 2026.
Use the filters below to find and compare flights from South Carolina to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Wed 10/7

6:00 am-10:45 pm

1 stop17h 45m

Guayaquil Jose Joaquin de Olmedo

Sun 10/11

6:00 am-9:14 pm

1 stop14h 14m

$409
Quickest round-trip

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Wed 10/7

11:00 am-10:45 pm

2 stops12h 45m

Guayaquil Jose Joaquin de Olmedo

Sun 10/11

6:00 am-9:14 pm

1 stop14h 14m

$414

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Wed 10/14

9:08 am-10:45 pm

1 stop14h 37m

Guayaquil Jose Joaquin de Olmedo

Sun 10/25

2:29 pm-9:57 am

1 stop18h 28m

$416

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Tue 10/6

5:00 pm-7:14 am

1 stop15h 14m

Guayaquil Jose Joaquin de Olmedo

Mon 10/12

4:19 pm-8:19 am

1 stop15h 00m

$444

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Tue 10/6

2:17 pm-7:14 am

2 stops17h 57m

Guayaquil Jose Joaquin de Olmedo

Mon 10/12

4:19 pm-4:05 pm

2 stops22h 46m

$448

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Thu 8/27

8:14 pm-10:40 am

1 stop15h 26m

Guayaquil Jose Joaquin de Olmedo

Sat 9/5

4:05 pm-10:10 am

1 stop17h 05m

$593

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Thu 8/27

8:14 pm-2:35 pm

2 stops19h 21m

Guayaquil Jose Joaquin de Olmedo

Sat 9/5

4:05 pm-10:10 am

1 stop17h 05m

$632

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Thu 9/3

5:27 pm-3:22 pm

1 stop22h 55m

Guayaquil Jose Joaquin de Olmedo

Mon 9/7

1:25 pm-4:31 pm

1 stop26h 06m

$660

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

Wed 9/23

10:10 am-11:37 pm

2 stops14h 27m

Guayaquil Jose Joaquin de Olmedo

Fri 9/25

8:28 am-9:55 am

2 stops48h 27m

$925

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

Wed 9/23

10:10 am-5:30 pm

2 stops32h 20m

Guayaquil Jose Joaquin de Olmedo

Fri 9/25

12:22 pm-3:16 pm

2 stops25h 54m

$1,163

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from South Carolina to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on South Carolina to Guayaquil flights?

You could potentially save up to 9% on your flight if you consider stops on a South Carolina to Guayaquil flight.

Cheap South Carolina to Guayaquil flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Guayaquil

Fastest flight time

7h 22m

Direct flights

None
The fastest flight from South Carolina to Guayaquil takes 7h 22m
There are no direct flights from South Carolina to Guayaquil. There are no popular flight routes from South Carolina to Guayaquil.
Search flight deals

Frequently asked questions about flying from South Carolina to Guayaquil

  • When did momondo last update prices for flights from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport refresh daily.

  • How many operators does momondo search for flights from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The travel and health documents required for your trip to Guayaquil Jose Joaquin de Olmedo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guayaquil Jose Joaquin de Olmedo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from South Carolina to Guayaquil

Compare and see reviews for airlines that fly from South Carolina to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $664Free CancellationRating
7.1
11,835 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Guayaquil?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Guayaquil from South Carolina.

Can I find flights from South Carolina to Guayaquil with flexible booking policies on momondo?

momondo does allow users to show only those flights to Guayaquil from South Carolina which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from South Carolina to Guayaquil?

Once all potential South Carolina to Guayaquil flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from South Carolina to Guayaquil right now. Can momondo alert me if prices change?

Price alerts on flights to Guayaquil from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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