Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from South Carolina to Detroit from $66

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Detroit departing on 4/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from South Carolina to Detroit

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
12:04 pm - 8:46 am
CHS
-
DTW
20h 42m
1 stop
Spirit Airlines Logo
9:53 pm - 11:09 am
DTW
-
CHS
13h 16m
1 stop
$143Spirit Airlines
토, 3월 14 - 화, 3월 17
Multiple Airlines Logo
9:18 am - 3:50 pm
CLT
-
DTW
6h 32m
1 stop
Multiple Airlines Logo
1:58 pm - 7:14 pm
DTW
-
CLT
5h 16m
1 stop
$147Multiple Airlines
화, 4월 14 - 토, 4월 18
Multiple Airlines Logo
1:59 pm - 8:19 pm
CLT
-
DTW
6h 20m
1 stop
Multiple Airlines Logo
2:06 pm - 8:01 pm
DTW
-
CLT
5h 55m
1 stop
$148Multiple Airlines
화, 3월 17 - 화, 3월 24
Frontier Logo
11:48 am - 1:47 pm
CLT
-
DTW
1h 59mnonstop
Frontier Logo
10:10 pm - 9:18 am
DTW
-
CLT
11h 08m
1 stop
$154Frontier
목, 5월 7 - 일, 5월 10
Frontier Logo
7:30 am - 9:29 am
CLT
-
DTW
1h 59mnonstop
Frontier Logo
8:51 pm - 10:42 pm
DTW
-
CLT
1h 51mnonstop
$156Frontier
목, 4월 9 - 일, 4월 12
United Airlines Logo
7:45 pm - 11:51 pm
CAE
-
DTW
4h 06m
1 stop
United Airlines Logo
6:00 am - 9:56 am
DTW
-
CAE
3h 56m
1 stop
$269United Airlines
토, 5월 23 - 토, 6월 6
American Airlines Logo
6:15 pm - 11:03 pm
HHH
-
DTW
4h 48m
1 stop
American Airlines Logo
10:01 am - 3:41 pm
DTW
-
HHH
5h 40m
1 stop
$269American Airlines
월, 3월 23 - 화, 3월 31
American Airlines Logo
4:11 pm - 10:16 pm
HHH
-
DTW
6h 05m
1 stop
American Airlines Logo
6:14 am - 4:44 pm
DTW
-
HHH
10h 30m
2 stops
$274American Airlines
월, 3월 23 - 화, 3월 31
Delta Logo
6:50 am - 11:01 am
CAE
-
DTW
4h 11m
1 stop
Delta Logo
2:01 pm - 7:58 pm
DTW
-
CAE
5h 57m
1 stop
$290Delta
목, 3월 26 - 목, 4월 2
Delta Logo
4:00 pm - 10:40 pm
HHH
-
DTW
6h 40m
1 stop
Delta Logo
12:15 pm - 11:28 am
DTW
-
HHH
23h 13m
1 stop
$301Delta
수, 4월 22 - 월, 4월 27

Spirit Airlines flights from South Carolina to Detroit Metropolitan Wayne County Airport

Our best Spirit Airlines deals on South Carolina to Detroit Metropolitan Wayne County Airport flight tickets
Spirit Airlines
Mar 14
CHS12:04 pmCharleston
20h 42m
1 stop
DTW8:46 amDetroit Metropolitan Wayne County
Mar 17
DTW9:53 pmDetroit Metropolitan Wayne County
13h 16m
1 stop
CHS11:09 amCharleston
$143
Spirit Airlines
Mar 17
CLT9:00 pmCharlotte Douglas
12h 23m
1 stop
DTW9:23 amDetroit Metropolitan Wayne County
Mar 24
DTW6:00 amDetroit Metropolitan Wayne County
14h 01m
1 stop
CLT8:01 pmCharlotte Douglas
$148
Spirit Airlines
Apr 24
CLT11:15 amCharlotte Douglas
4h 58m
1 stop
DTW4:13 pmDetroit Metropolitan Wayne County
Apr 30
DTW11:15 amDetroit Metropolitan Wayne County
9h 18m
1 stop
CLT8:33 pmCharlotte Douglas
$151

Southwest flights from South Carolina to Detroit Metropolitan Wayne County Airport

Our best Southwest deals on South Carolina to Detroit Metropolitan Wayne County Airport flight tickets
Southwest
Apr 22
MYR11:15 amMyrtle Beach Intl
11h 15m
2 stops
DTW10:30 pmDetroit Metropolitan Wayne County
Apr 27
DTW3:35 pmDetroit Metropolitan Wayne County
5h 15m
1 stop
MYR8:50 pmMyrtle Beach Intl
$257
Southwest
Apr 28
SAV6:40 amSavannah/Hilton Head
6h 00m
1 stop
DTW12:40 pmDetroit Metropolitan Wayne County
May 2
DTW7:20 amDetroit Metropolitan Wayne County
9h 20m
2 stops
SAV4:40 pmSavannah/Hilton Head
$324
Southwest
Apr 25
GSP5:25 pmGreenville
4h 00m
1 stop
DTW9:25 pmDetroit Metropolitan Wayne County
Apr 29
DTW1:20 pmDetroit Metropolitan Wayne County
6h 40m
1 stop
GSP8:00 pmGreenville
$325

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated 3월 2, 2026.
Use the filters below to find and compare flights from South Carolina to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonDetroit

CHS - DTW

CHSDTW

Charleston

토 3/14

12:04 pm-8:46 am

1 stop20h 42m

Detroit Metropolitan Wayne County

화 3/17

9:53 pm-11:09 am

1 stop13h 16m

$143

CharlotteDetroit

CLT - DTW

CLTDTW

Charlotte Douglas

화 4/14

9:18 am-3:50 pm

1 stop6h 32m

Detroit Metropolitan Wayne County

토 4/18

1:58 pm-7:14 pm

1 stop5h 16m

$147

CharlotteDetroit

CLT - DTW

CLTDTW

Charlotte Douglas

화 3/17

1:59 pm-8:19 pm

1 stop6h 20m

Detroit Metropolitan Wayne County

화 3/24

2:06 pm-8:01 pm

1 stop5h 55m

$148

CharlotteDetroit

CLT - DTW

CLTDTW

Charlotte Douglas

목 5/7

11:48 am-1:47 pm

Nonstop1h 59m

Detroit Metropolitan Wayne County

일 5/10

10:10 pm-9:18 am

1 stop11h 08m

$154

CharlotteDetroit

CLT - DTW

CLTDTW

Charlotte Douglas

목 4/9

7:30 am-9:29 am

Nonstop1h 59m

Detroit Metropolitan Wayne County

일 4/12

8:51 pm-10:42 pm

Nonstop1h 51m

$156

ColumbiaDetroit

CAE - DTW

CAEDTW

Columbia Metropolitan

토 5/23

7:45 pm-11:51 pm

1 stop4h 06m

Detroit Metropolitan Wayne County

토 6/6

6:00 am-9:56 am

1 stop3h 56m

$269

Hilton Head IslandDetroit

HHH - DTW

HHHDTW

Hilton Head Island

월 3/23

6:15 pm-11:03 pm

1 stop4h 48m

Detroit Metropolitan Wayne County

화 3/31

10:01 am-3:41 pm

1 stop5h 40m

$269

Hilton Head IslandDetroit

HHH - DTW

HHHDTW

Hilton Head Island

월 3/23

4:11 pm-10:16 pm

1 stop6h 05m

Detroit Metropolitan Wayne County

화 3/31

6:14 am-4:44 pm

2 stops10h 30m

$274

ColumbiaDetroit

CAE - DTW

CAEDTW

Columbia Metropolitan

목 3/26

6:50 am-11:01 am

1 stop4h 11m

Detroit Metropolitan Wayne County

목 4/2

2:01 pm-7:58 pm

1 stop5h 57m

$290

Hilton Head IslandDetroit

HHH - DTW

HHHDTW

Hilton Head Island

수 4/22

4:00 pm-10:40 pm

1 stop6h 40m

Detroit Metropolitan Wayne County

월 4/27

12:15 pm-11:28 am

1 stop23h 13m

$301

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Detroit from

How to get the cheapest flight ticket from South Carolina to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Detroit Metropolitan Wayne County Airport?

The cheapest month to fly to Detroit Metropolitan Wayne County Airport from South Carolina is in June. Flight prices, which tend to average around $219, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of June, then book flights to Detroit Metropolitan Wayne County Airport from South Carolina during August instead. Flights to Detroit Metropolitan Wayne County Airport in August, while not as cheap as those in June, still average around $259.

What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?

The cheapest day to depart from South Carolina to Detroit Metropolitan Wayne County Airport is on a Thursday when prices can be found for as low as $286. Be sure to avoid booking your departure on a Tuesday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Tuesday is $551.

What is the cheapest time of day to depart on your flight to Detroit Metropolitan Wayne County Airport?

Flying to Detroit Metropolitan Wayne County Airport from South Carolina in the evening is the least expensive time of day to depart. momondo users have found prices as low as $123 when looking at flights departing in the evening. Flights to Detroit Metropolitan Wayne County Airport are more costly in the afternoon, with an average ticket price of $480. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest South Carolina to Detroit Metropolitan Wayne County flight route?

Fly from Greenville to Detroit Metropolitan Wayne County for the best South Carolina - Detroit Metropolitan Wayne County flight prices

How far in advance should I book a flight to Detroit Metropolitan Wayne County Airport?

You are more likely to see cheaper flights to Detroit Metropolitan Wayne County Airport from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Detroit Metropolitan Wayne County Airport for around $323 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Detroit Metropolitan Wayne County Airport from South Carolina for as low as $201 on momondo.

What cabin class options are available on South Carolina to Detroit Metropolitan Wayne County flights?

There are 4 cabin classes available to choose from on South Carolina to Detroit Metropolitan Wayne County flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Detroit Metropolitan Wayne County Airport flights?

You could potentially save up to 38% on your flight if you consider stops on a South Carolina to Detroit Metropolitan Wayne County Airport flight.

Cheap South Carolina to Detroit Metropolitan Wayne County Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Detroit Metropolitan Wayne County Airport

Best Price Found

$209

Fastest flight time

1h 44m

Direct flights

Every day
The best one-way flight to Detroit Metropolitan Wayne County Airport from South Carolina in the past 72 hours is $209. The best round-trip flight deal from South Carolina to Detroit Metropolitan Wayne County Airport found on momondo in the last 72 hours is $359.
The fastest flight from South Carolina to Detroit Metropolitan Wayne County Airport takes 1h 44m
Direct flights go from South Carolina to Detroit Metropolitan Wayne County Airport every day.
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Detroit Metropolitan Wayne County Airport?

    Prices for flights from South Carolina to Detroit Metropolitan Wayne County Airport refresh daily.

  • How many operators does momondo search for flights from South Carolina to Detroit Metropolitan Wayne County Airport?

  • How old do you have to be to fly from South Carolina to Detroit Metropolitan Wayne County Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The travel and health documents you'll need for your trip to Detroit Metropolitan Wayne County Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Detroit Metropolitan Wayne County Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from South Carolina to Detroit Metropolitan Wayne County Airport?

Best airlines flying from South Carolina to Detroit Metropolitan Wayne County Airport

Compare and see reviews for airlines that fly from South Carolina to Detroit Metropolitan Wayne County Airport with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $70Free CancellationRating
6.3
8,487 reviews
Search Spirit Airlines flights
DeltaPriceFrom $140Free CancellationRating
7.9
8,237 reviews
Search Delta flights
American AirlinesPriceFrom $198Free CancellationRating
7.1
11,369 reviews
Search American Airlines flights
SouthwestPriceFrom $243Free CancellationRating
8.0
4,306 reviews
Search Southwest flights

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Warren
Dearborn
Romulus
Troy
Monroe
Southfield
Livonia
Novi
Port Clinton
Roseville
Port Huron
Sterling Heights
Brighton
Dundee
Ypsilanti
Pontiac
Plymouth
Farmington Hills

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Detroit?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Detroit. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Detroit with flexible booking policies on momondo?

momondo does allow users to show only those flights to Detroit from South Carolina which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from South Carolina to Detroit?

Once you have performed a search for South Carolina to Detroit flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Detroit right now. Can momondo alert me if prices change?

If you are not ready to book a flight from South Carolina to Detroit now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Detroit and let you know when they change.

An easier way to manage your Detroit Metropolitan Wayne County Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
수 4/1
수 4/8
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Detroit