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Cheap flights from South Carolina to Detroit from $70

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Detroit departing on 5/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from South Carolina to Detroit

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:18 pm - 5:16 pm
MYR
-
DTW
22h 58m
1 stop
Multiple Airlines Logo
9:50 pm - 9:46 am
DTW
-
MYR
11h 56m
1 stop
$192Multiple Airlines
Thu, May 7 - Tue, May 12
Spirit Airlines Logo
2:27 pm - 7:23 pm
CHS
-
DTW
4h 56m
1 stop
Spirit Airlines Logo
8:57 am - 1:32 pm
DTW
-
CHS
4h 35m
1 stop
$193Spirit Airlines
Fri, Jul 3 - Wed, Jul 8
Frontier Logo
6:00 am - 6:58 pm
CLT
-
DTW
12h 58m
1 stop
Frontier Logo
8:52 am - 4:11 pm
DTW
-
CLT
7h 19m
1 stop
$204Frontier
Sat, Jun 27 - Tue, Jul 7
Frontier Logo
6:00 am - 6:58 pm
CLT
-
DTW
12h 58m
1 stop
Frontier Logo
8:52 am - 4:11 pm
DTW
-
CLT
7h 19m
1 stop
$210Frontier
Sat, Jun 27 - Tue, Jul 7
American Airlines Logo
8:09 pm - 12:25 am
SAV
-
DTW
4h 16m
1 stop
American Airlines Logo
4:31 pm - 9:09 pm
DTW
-
SAV
4h 38m
1 stop
$231American Airlines
Fri, May 8 - Tue, May 12
American Airlines Logo
6:57 pm - 11:56 pm
SAV
-
DTW
4h 59m
1 stop
American Airlines Logo
7:49 pm - 11:53 pm
DTW
-
SAV
4h 04m
1 stop
$241American Airlines
Thu, Apr 30 - Mon, May 4
United Airlines Logo
6:36 pm - 11:43 pm
SAV
-
DTW
5h 07m
1 stop
United Airlines Logo
7:05 am - 2:16 pm
DTW
-
SAV
7h 11m
1 stop
$267United Airlines
Mon, Jun 22 - Wed, Jun 24
United Airlines Logo
12:19 pm - 5:19 pm
SAV
-
DTW
5h 00m
1 stop
United Airlines Logo
11:40 am - 7:26 pm
DTW
-
SAV
7h 46m
2 stops
$272United Airlines
Fri, May 8 - Tue, May 12
Delta Logo
10:11 am - 3:55 pm
CAE
-
DTW
5h 44m
1 stop
Delta Logo
5:20 am - 9:22 am
DTW
-
CAE
4h 02m
1 stop
$295Delta
Sat, Aug 1 - Wed, Aug 5
Delta Logo
4:34 pm - 11:09 pm
CAE
-
DTW
6h 35m
1 stop
Delta Logo
5:59 pm - 11:10 pm
DTW
-
CAE
5h 11m
1 stop
$329Delta
Fri, May 15 - Mon, Jun 8

Spirit Airlines flights from South Carolina to Detroit Metropolitan Wayne County Airport

Our best Spirit Airlines deals on South Carolina to Detroit Metropolitan Wayne County Airport flight tickets
Spirit Airlines
Jul 3
CHS2:27 pmCharleston
4h 56m
1 stop
DTW7:23 pmDetroit Metropolitan Wayne County
Jul 8
DTW8:57 amDetroit Metropolitan Wayne County
4h 35m
1 stop
CHS1:32 pmCharleston
$193
Spirit Airlines
May 6
MYR9:39 pmMyrtle Beach Intl
10h 13m
1 stop
DTW7:52 amDetroit Metropolitan Wayne County
May 12
DTW9:50 pmDetroit Metropolitan Wayne County
11h 56m
1 stop
MYR9:46 amMyrtle Beach Intl
$197
Spirit Airlines
May 12
MYR9:39 pmMyrtle Beach Intl
10h 13m
1 stop
DTW7:52 amDetroit Metropolitan Wayne County
May 19
DTW9:50 pmDetroit Metropolitan Wayne County
11h 56m
1 stop
MYR9:46 amMyrtle Beach Intl
$206

Frontier flights from South Carolina to Detroit Metropolitan Wayne County Airport

Our best Frontier deals on South Carolina to Detroit Metropolitan Wayne County Airport flight tickets
Frontier
Jun 27
CLT6:00 amCharlotte Douglas
12h 58m
1 stop
DTW6:58 pmDetroit Metropolitan Wayne County
Jul 7
DTW8:52 amDetroit Metropolitan Wayne County
7h 19m
1 stop
CLT4:11 pmCharlotte Douglas
$204
Frontier
Jun 27
CLT6:00 amCharlotte Douglas
12h 58m
1 stop
DTW6:58 pmDetroit Metropolitan Wayne County
Jul 7
DTW8:52 amDetroit Metropolitan Wayne County
7h 19m
1 stop
CLT4:11 pmCharlotte Douglas
$210
Frontier
Jun 25
CLT6:00 amCharlotte Douglas
12h 58m
1 stop
DTW6:58 pmDetroit Metropolitan Wayne County
Jun 29
DTW12:42 pmDetroit Metropolitan Wayne County
5h 06m
1 stop
CLT5:48 pmCharlotte Douglas
$230

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 17, 2026.
Use the filters below to find and compare flights from South Carolina to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachDetroit

MYR - DTW

MYRDTW

Myrtle Beach Intl

Thu 5/7

6:18 pm-5:16 pm

1 stop22h 58m

Detroit Metropolitan Wayne County

Tue 5/12

9:50 pm-9:46 am

1 stop11h 56m

$192

CharlestonDetroit

CHS - DTW

CHSDTW

Charleston

Fri 7/3

2:27 pm-7:23 pm

1 stop4h 56m

Detroit Metropolitan Wayne County

Wed 7/8

8:57 am-1:32 pm

1 stop4h 35m

$193

CharlotteDetroit

CLT - DTW

CLTDTW

Charlotte Douglas

Sat 6/27

6:00 am-6:58 pm

1 stop12h 58m

Detroit Metropolitan Wayne County

Tue 7/7

8:52 am-4:11 pm

1 stop7h 19m

$204

CharlotteDetroit

CLT - DTW

CLTDTW

Charlotte Douglas

Sat 6/27

6:00 am-6:58 pm

1 stop12h 58m

Detroit Metropolitan Wayne County

Tue 7/7

8:52 am-4:11 pm

1 stop7h 19m

$210
Quickest round-trip

SavannahDetroit

SAV - DTW

SAVDTW

Savannah/Hilton Head

Fri 5/8

8:09 pm-12:25 am

1 stop4h 16m

Detroit Metropolitan Wayne County

Tue 5/12

4:31 pm-9:09 pm

1 stop4h 38m

$231

SavannahDetroit

SAV - DTW

SAVDTW

Savannah/Hilton Head

Thu 4/30

6:57 pm-11:56 pm

1 stop4h 59m

Detroit Metropolitan Wayne County

Mon 5/4

7:49 pm-11:53 pm

1 stop4h 04m

$241

SavannahDetroit

SAV - DTW

SAVDTW

Savannah/Hilton Head

Mon 6/22

6:36 pm-11:43 pm

1 stop5h 07m

Detroit Metropolitan Wayne County

Wed 6/24

7:05 am-2:16 pm

1 stop7h 11m

$267

SavannahDetroit

SAV - DTW

SAVDTW

Savannah/Hilton Head

Fri 5/8

12:19 pm-5:19 pm

1 stop5h 00m

Detroit Metropolitan Wayne County

Tue 5/12

11:40 am-7:26 pm

2 stops7h 46m

$272

ColumbiaDetroit

CAE - DTW

CAEDTW

Columbia Metropolitan

Sat 8/1

10:11 am-3:55 pm

1 stop5h 44m

Detroit Metropolitan Wayne County

Wed 8/5

5:20 am-9:22 am

1 stop4h 02m

$295

ColumbiaDetroit

CAE - DTW

CAEDTW

Columbia Metropolitan

Fri 5/15

4:34 pm-11:09 pm

1 stop6h 35m

Detroit Metropolitan Wayne County

Mon 6/8

5:59 pm-11:10 pm

1 stop5h 11m

$329

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from South Carolina to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Detroit Metropolitan Wayne County Airport?

The cheapest month to fly to Detroit Metropolitan Wayne County Airport from South Carolina is in June. Flight prices, which tend to average around $219, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of June, then book flights to Detroit Metropolitan Wayne County Airport from South Carolina during August instead. Flights to Detroit Metropolitan Wayne County Airport in August, while not as cheap as those in June, still average around $259.

What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?

The cheapest day to depart from South Carolina to Detroit Metropolitan Wayne County Airport is on a Thursday when prices can be found for as low as $307. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Sunday is $494.

What is the cheapest time of day to depart on your flight to Detroit Metropolitan Wayne County Airport?

Flying to Detroit Metropolitan Wayne County Airport from South Carolina in the evening is the least expensive time of day to depart. momondo users have found prices as low as $123 when looking at flights departing in the evening. Flights to Detroit Metropolitan Wayne County Airport are more costly in the afternoon, with an average ticket price of $473. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest South Carolina to Detroit Metropolitan Wayne County flight route?

Fly from Charleston to Detroit Metropolitan Wayne County for the best South Carolina - Detroit Metropolitan Wayne County flight prices

How far in advance should I book a flight to Detroit Metropolitan Wayne County Airport?

You are more likely to see cheaper flights to Detroit Metropolitan Wayne County Airport from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Detroit Metropolitan Wayne County Airport for around $323 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Detroit Metropolitan Wayne County Airport from South Carolina for as low as $194 on momondo.

What cabin class options are available on South Carolina to Detroit Metropolitan Wayne County flights?

There are 4 cabin classes available to choose from on South Carolina to Detroit Metropolitan Wayne County flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Detroit Metropolitan Wayne County Airport flights?

You could potentially save up to 48% on your flight if you consider stops on a South Carolina to Detroit Metropolitan Wayne County Airport flight.

Cheap South Carolina to Detroit Metropolitan Wayne County Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Detroit Metropolitan Wayne County Airport

Best Price Found

$234

Fastest flight time

1h 44m

Direct flights

Every day
The best one-way flight to Detroit Metropolitan Wayne County Airport from South Carolina in the past 72 hours is $234. The best round-trip flight deal from South Carolina to Detroit Metropolitan Wayne County Airport found on momondo in the last 72 hours is $339.
The fastest flight from South Carolina to Detroit Metropolitan Wayne County Airport takes 1h 44m
Direct flights go from South Carolina to Detroit Metropolitan Wayne County Airport every day.
Search flight deals

Frequently asked questions about flying from South Carolina to Detroit Metropolitan Wayne County Airport

  • When did momondo last update prices for flights from South Carolina to Detroit Metropolitan Wayne County Airport?

    Prices for flights from South Carolina to Detroit Metropolitan Wayne County Airport refresh daily.

  • How many operators does momondo search for flights from South Carolina to Detroit Metropolitan Wayne County Airport?

  • How old do you have to be to fly from South Carolina to Detroit Metropolitan Wayne County Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The travel and health documents you'll need for your trip to Detroit Metropolitan Wayne County Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Detroit Metropolitan Wayne County Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from South Carolina to Detroit Metropolitan Wayne County Airport?

Best airlines flying from South Carolina to Detroit Metropolitan Wayne County Airport

Compare and see reviews for airlines that fly from South Carolina to Detroit Metropolitan Wayne County Airport with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $70Free CancellationRating
6.3
8,618 reviews
Search Spirit Airlines flights
DeltaPriceFrom $140Free CancellationRating
7.9
8,412 reviews
Search Delta flights
American AirlinesPriceFrom $198Free CancellationRating
7.1
11,598 reviews
Search American Airlines flights

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Dearborn
Warren
Romulus
Troy
Monroe
Southfield
Livonia
Novi
Port Clinton
Roseville
Sterling Heights
Port Huron
Dundee
Brighton
Ypsilanti
Pontiac
Farmington Hills
Plymouth

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Detroit?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Detroit. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Detroit with flexible booking policies on momondo?

momondo does allow users to show only those flights to Detroit from South Carolina which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from South Carolina to Detroit?

Once you have performed a search for South Carolina to Detroit flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Detroit right now. Can momondo alert me if prices change?

If you are not ready to book a flight from South Carolina to Detroit now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Detroit and let you know when they change.

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