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Cheap flights from South Carolina to Detroit from $61

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Detroit departing on 1/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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Spirit Airlines Logo
6:15 pm - 11:09 pmCHS-DTW
4h 54m1 stop
Spirit Airlines Logo
6:00 am - 11:00 amDTW-CHS
5h 00m1 stop
$117Spirit Airlines
Find Deal
Tue, Dec 2 - Sat, Dec 6
Spirit Airlines Logo
10:00 am - 11:09 pmSAV-DTW
13h 09m1 stop
Spirit Airlines Logo
6:00 am - 12:23 pmDTW-SAV
6h 23m1 stop
$132Spirit Airlines
Find Deal
Tue, Dec 2 - Sat, Dec 6
Multiple Airlines Logo
1:37 pm - 8:29 amCLT-DTW
18h 52m1 stop
Multiple Airlines Logo
12:38 pm - 8:00 pmDTW-CLT
7h 22m1 stop
$152Multiple Airlines
Find Deal
Tue, Dec 9 - Sat, Dec 13
Frontier Logo
9:24 am - 11:20 amCLT-DTW
1h 56mnonstop
Frontier Logo
12:15 pm - 2:08 pmDTW-CLT
1h 53mnonstop
$153Frontier
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Thu, Dec 18 - Sun, Dec 21
Multiple Airlines Logo
5:05 pm - 12:19 amCHS-DTW
7h 14m1 stop
Multiple Airlines Logo
10:54 am - 5:36 pmDTW-CHS
6h 42m1 stop
$153Multiple Airlines
Find Deal
Mon, Jan 12 - Thu, Jan 22
Frontier Logo
6:26 pm - 10:13 amCLT-DTW
15h 47m1 stop
Frontier Logo
2:43 pm - 4:38 pmDTW-CLT
25h 55m1 stop
$158Frontier
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Fri, Dec 19 - Mon, Dec 22
Delta Logo
5:14 pm - 7:07 pmCLT-DTW
1h 53mnonstop
Delta Logo
8:02 pm - 9:55 pmDTW-CLT
1h 53mnonstop
$159Delta
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Sat, Dec 6 - Tue, Dec 9
Delta Logo
8:45 am - 12:56 pmCAE-DTW
4h 11m1 stop
Delta Logo
6:05 pm - 11:48 pmDTW-CAE
5h 43m1 stop
$249Delta
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Wed, Feb 18 - Sat, Feb 21
American Airlines Logo
5:06 am - 9:48 amCAE-DTW
4h 42m1 stop
American Airlines Logo
11:55 am - 4:54 pmDTW-CAE
4h 59m1 stop
$309American Airlines
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Fri, Nov 28 - Tue, Dec 2
American Airlines Logo
5:29 pm - 10:45 pmCAE-DTW
5h 16m1 stop
American Airlines Logo
2:11 pm - 10:03 pmDTW-CAE
7h 52m2 stops
$324American Airlines
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Wed, Feb 18 - Sat, Feb 21

Spirit Airlines flights from South Carolina to Detroit Metropolitan Wayne County Airport

Our best Spirit Airlines deals on South Carolina to Detroit Metropolitan Wayne County Airport flight tickets
Spirit Airlines
Dec 2
CHS6:15 pmCharleston
4h 54m
1 stop
DTW11:09 pmDetroit Metropolitan Wayne County
Dec 6
DTW6:00 amDetroit Metropolitan Wayne County
5h 00m
1 stop
CHS11:00 amCharleston
$117
Find similar
Spirit Airlines
Dec 2
SAV10:00 amSavannah/Hilton Head
13h 09m
1 stop
DTW11:09 pmDetroit Metropolitan Wayne County
Dec 6
DTW6:00 amDetroit Metropolitan Wayne County
6h 23m
1 stop
SAV12:23 pmSavannah/Hilton Head
$132
Find similar
Spirit Airlines
Dec 4
CHS11:55 amCharleston
20h 12m
2 stops
DTW8:07 amDetroit Metropolitan Wayne County
Dec 8
DTW6:00 amDetroit Metropolitan Wayne County
5h 00m
1 stop
CHS11:00 amCharleston
$144
Find similar

United Airlines flights from South Carolina to Detroit Metropolitan Wayne County Airport

Our best United Airlines deals on South Carolina to Detroit Metropolitan Wayne County Airport flight tickets
United Airlines
Dec 2
CAE10:20 amColumbia Metropolitan
13h 30m
2 stops
DTW11:50 pmDetroit Metropolitan Wayne County
Dec 6
DTW7:25 amDetroit Metropolitan Wayne County
6h 22m
1 stop
CAE1:47 pmColumbia Metropolitan
$354
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United Airlines
Nov 18
CAE2:50 pmColumbia Metropolitan
8h 48m
2 stops
DTW11:38 pmDetroit Metropolitan Wayne County
Nov 22
DTW2:35 pmDetroit Metropolitan Wayne County
4h 19m
1 stop
CAE6:54 pmColumbia Metropolitan
$444
Find similar
United Airlines
Nov 22
CAE2:29 pmColumbia Metropolitan
7h 46m
1 stop
DTW10:15 pmDetroit Metropolitan Wayne County
Nov 24
DTW5:45 amDetroit Metropolitan Wayne County
8h 02m
2 stops
CAE1:47 pmColumbia Metropolitan
$493
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momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from South Carolina to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonDetroit

CHS - DTW

CHSDTW

Charleston

Tue 12/2

6:15 pm-11:09 pm

1 stop4h 54m

Detroit Metropolitan Wayne County

Sat 12/6

6:00 am-11:00 am

1 stop5h 00m

$117

SavannahDetroit

SAV - DTW

SAVDTW

Savannah/Hilton Head

Tue 12/2

10:00 am-11:09 pm

1 stop13h 09m

Detroit Metropolitan Wayne County

Sat 12/6

6:00 am-12:23 pm

1 stop6h 23m

$132

CharlotteDetroit

CLT - DTW

CLTDTW

Charlotte Douglas

Tue 12/9

1:37 pm-8:29 am

1 stop18h 52m

Detroit Metropolitan Wayne County

Sat 12/13

12:38 pm-8:00 pm

1 stop7h 22m

$152

CharlotteDetroit

CLT - DTW

CLTDTW

Charlotte Douglas

Thu 12/18

9:24 am-11:20 am

Nonstop1h 56m

Detroit Metropolitan Wayne County

Sun 12/21

12:15 pm-2:08 pm

Nonstop1h 53m

$153

CharlestonDetroit

CHS - DTW

CHSDTW

Charleston

Mon 1/12

5:05 pm-12:19 am

1 stop7h 14m

Detroit Metropolitan Wayne County

Thu 1/22

10:54 am-5:36 pm

1 stop6h 42m

$153

CharlotteDetroit

CLT - DTW

CLTDTW

Charlotte Douglas

Fri 12/19

6:26 pm-10:13 am

1 stop15h 47m

Detroit Metropolitan Wayne County

Mon 12/22

2:43 pm-4:38 pm

1 stop25h 55m

$158

CharlotteDetroit

CLT - DTW

CLTDTW

Charlotte Douglas

Sat 12/6

5:14 pm-7:07 pm

Nonstop1h 53m

Detroit Metropolitan Wayne County

Tue 12/9

8:02 pm-9:55 pm

Nonstop1h 53m

$159

ColumbiaDetroit

CAE - DTW

CAEDTW

Columbia Metropolitan

Wed 2/18

8:45 am-12:56 pm

1 stop4h 11m

Detroit Metropolitan Wayne County

Sat 2/21

6:05 pm-11:48 pm

1 stop5h 43m

$249

ColumbiaDetroit

CAE - DTW

CAEDTW

Columbia Metropolitan

Fri 11/28

5:06 am-9:48 am

1 stop4h 42m

Detroit Metropolitan Wayne County

Tue 12/2

11:55 am-4:54 pm

1 stop4h 59m

$309

ColumbiaDetroit

CAE - DTW

CAEDTW

Columbia Metropolitan

Wed 2/18

5:29 pm-10:45 pm

1 stop5h 16m

Detroit Metropolitan Wayne County

Sat 2/21

2:11 pm-10:03 pm

2 stops7h 52m

$324

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from South Carolina to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Detroit Metropolitan Wayne County Airport?

The cheapest month to fly to Detroit Metropolitan Wayne County Airport from South Carolina is in June. Flight prices, which tend to average around $219, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of June, then book flights to Detroit Metropolitan Wayne County Airport from South Carolina during August instead. Flights to Detroit Metropolitan Wayne County Airport in August, while not as cheap as those in June, still average around $259.

What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?

The cheapest day to depart from South Carolina to Detroit Metropolitan Wayne County Airport is on a Thursday when prices can be found for as low as $292. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Sunday is $560.

What is the cheapest time of day to depart on your flight to Detroit Metropolitan Wayne County Airport?

Flying to Detroit Metropolitan Wayne County Airport from South Carolina in the evening is the least expensive time of day to depart. momondo users have found prices as low as $123 when looking at flights departing in the evening. Flights to Detroit Metropolitan Wayne County Airport are more costly in the afternoon, with an average ticket price of $492. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest South Carolina to Detroit Metropolitan Wayne County flight route?

Fly from Myrtle Beach Intl to Detroit Metropolitan Wayne County for the best South Carolina - Detroit Metropolitan Wayne County flight prices

How far in advance should I book a flight to Detroit Metropolitan Wayne County Airport?

You are more likely to see cheaper flights to Detroit Metropolitan Wayne County Airport from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Detroit Metropolitan Wayne County Airport for around $336 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Detroit Metropolitan Wayne County Airport from South Carolina for as low as $201 on momondo.

What cabin class options are available on South Carolina to Detroit Metropolitan Wayne County flights?

There are 4 cabin classes available to choose from on South Carolina to Detroit Metropolitan Wayne County flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Detroit Metropolitan Wayne County Airport flights?

You could potentially save up to 23% on your flight if you consider stops on a South Carolina to Detroit Metropolitan Wayne County Airport flight.

Cheap South Carolina to Detroit Metropolitan Wayne County Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Detroit Metropolitan Wayne County Airport

Best Price Found

$179

Fastest flight time

1h 45m

Direct flights

Every day
The best one-way flight to Detroit Metropolitan Wayne County Airport from South Carolina in the past 72 hours is $179. The best round-trip flight deal from South Carolina to Detroit Metropolitan Wayne County Airport found on momondo in the last 72 hours is $259.
The fastest flight from South Carolina to Detroit Metropolitan Wayne County Airport takes 1h 45m
Direct flights go from South Carolina to Detroit Metropolitan Wayne County Airport every day.
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Detroit Metropolitan Wayne County Airport?

    Prices for flights from South Carolina to Detroit Metropolitan Wayne County Airport refresh daily.

  • How many operators does momondo search for flights from South Carolina to Detroit Metropolitan Wayne County Airport?

  • How old do you have to be to fly from South Carolina to Detroit Metropolitan Wayne County Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The travel and health documents you'll need for your trip to Detroit Metropolitan Wayne County Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Detroit Metropolitan Wayne County Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from South Carolina to Detroit Metropolitan Wayne County Airport?

Best airlines flying from South Carolina to Detroit Metropolitan Wayne County Airport

Compare and see reviews for airlines that fly from South Carolina to Detroit Metropolitan Wayne County Airport with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $72Free CancellationRating
6.3
8,144 reviews
Search Spirit Airlines flights
DeltaPriceFrom $159Free CancellationRating
7.9
8,006 reviews
Search Delta flights
American AirlinesPriceFrom $178Free CancellationRating
7.2
11,048 reviews
Search American Airlines flights
SouthwestPriceFrom $243Free CancellationRating
8.0
4,244 reviews
Search Southwest flights

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Warren
Southfield
Troy
Dearborn
Romulus
Monroe
Novi
Livonia
Port Clinton
Port Huron
Roseville
Sterling Heights
Brighton
Ypsilanti
Pontiac
Dundee
Madison Heights
Royal Oak

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Detroit?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Detroit. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Detroit with flexible booking policies on momondo?

momondo does allow users to show only those flights to Detroit from South Carolina which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from South Carolina to Detroit?

Once you have performed a search for South Carolina to Detroit flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Carolina to Detroit right now. Can momondo alert me if prices change?

If you are not ready to book a flight from South Carolina to Detroit now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Detroit and let you know when they change.

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