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Cheap flights from South Carolina to the Cayman Islands from $105

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to the Cayman Islands departing on 1/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from South Carolina to the Cayman Islands

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
7:00 am - 1:53 pmCLT-GCM
6h 53m1 stop
Spirit Airlines Logo
2:49 pm - 12:40 amGCM-CLT
9h 51m1 stop
$275Spirit Airlines
Find Deal
Thu, Jan 8 - Sun, Jan 18
Multiple Airlines Logo
6:56 pm - 1:53 pmCLT-GCM
18h 57m1 stop
Multiple Airlines Logo
2:49 pm - 9:47 pmGCM-CLT
6h 58m1 stop
$314Multiple Airlines
Find Deal
Wed, Feb 4 - Sun, Feb 8
Delta Logo
5:25 am - 12:40 pmCHS-GCM
7h 15m1 stop
Delta Logo
2:05 pm - 10:07 pmGCM-CHS
8h 02m1 stop
$320Delta
Find Deal
Mon, Jan 26 - Thu, Jan 29
Spirit Airlines Logo
6:01 pm - 1:53 pmCLT-GCM
19h 52m2 stops
Spirit Airlines Logo
2:49 pm - 12:40 amGCM-CLT
9h 51m1 stop
$327Spirit Airlines
Find Deal
Wed, Feb 4 - Sun, Feb 8
Spirit Airlines Logo
7:00 am - 4:55 pmCLT-GCM
9h 55m1 stop
Spirit Airlines Logo
5:56 pm - 11:29 pmGCM-CLT
5h 33m1 stop
$332Spirit Airlines
Find Deal
Sat, Dec 20 - Sat, Dec 27
Delta Logo
5:27 am - 11:00 amCHS-GCM
5h 33m1 stop
Delta Logo
3:07 pm - 9:04 pmGCM-CHS
5h 57m1 stop
$336Delta
Find Deal
Sat, Feb 28 - Sat, Mar 7
United Airlines Logo
6:30 am - 4:00 pmCHS-GCM
9h 30m1 stop
United Airlines Logo
2:50 pm - 10:35 amGCM-CHS
19h 45m1 stop
$352United Airlines
Find Deal
Thu, Dec 25 - Tue, Dec 30
American Airlines Logo
7:00 am - 3:25 pmCHS-GCM
8h 25m1 stop
American Airlines Logo
12:55 pm - 8:35 amGCM-CHS
19h 40m1 stop
$366American Airlines
Find Deal
Thu, Dec 25 - Sun, Dec 28
American Airlines Logo
7:42 pm - 11:26 amCHS-GCM
15h 44m1 stop
American Airlines Logo
8:50 am - 11:58 pmGCM-CHS
15h 08m1 stop
$380American Airlines
Find Deal
Mon, Jan 26 - Thu, Jan 29
United Airlines Logo
10:10 am - 1:45 pmSAV-GCM
27h 35m1 stop
United Airlines Logo
2:25 pm - 10:46 pmGCM-SAV
8h 21m1 stop
$524United Airlines
Find Deal
Thu, Jan 22 - Mon, Jan 26

Spirit Airlines flights from South Carolina to Cayman Islands

Our best Spirit Airlines deals on South Carolina to Cayman Islands flight tickets
Spirit Airlines
Jan 8
CLT7:00 amCharlotte Douglas
6h 53m
1 stop
GCM1:53 pmGeorge Town Owen Roberts Intl
Jan 18
GCM2:49 pmGeorge Town Owen Roberts Intl
9h 51m
1 stop
CLT12:40 amCharlotte Douglas
$275
Find similar
Spirit Airlines
Feb 4
CLT6:01 pmCharlotte Douglas
19h 52m
2 stops
GCM1:53 pmGeorge Town Owen Roberts Intl
Feb 8
GCM2:49 pmGeorge Town Owen Roberts Intl
9h 51m
1 stop
CLT12:40 amCharlotte Douglas
$327
Find similar
Spirit Airlines
Dec 20
CLT7:00 amCharlotte Douglas
9h 55m
1 stop
GCM4:55 pmGeorge Town Owen Roberts Intl
Dec 27
GCM5:56 pmGeorge Town Owen Roberts Intl
5h 33m
1 stop
CLT11:29 pmCharlotte Douglas
$332
Find similar

Delta flights from South Carolina to Cayman Islands

Our best Delta deals on South Carolina to Cayman Islands flight tickets
Delta
Jan 26
CHS5:25 amCharleston
7h 15m
1 stop
GCM12:40 pmGeorge Town Owen Roberts Intl
Jan 29
GCM2:05 pmGeorge Town Owen Roberts Intl
8h 02m
1 stop
CHS10:07 pmCharleston
$320
Find similar
Delta
Feb 28
CHS5:27 amCharleston
5h 33m
1 stop
GCM11:00 amGeorge Town Owen Roberts Intl
Mar 7
GCM3:07 pmGeorge Town Owen Roberts Intl
5h 57m
1 stop
CHS9:04 pmCharleston
$336
Find similar
Delta
Feb 7
CLT7:59 amCharlotte Douglas
6h 01m
1 stop
GCM2:00 pmGeorge Town Owen Roberts Intl
Feb 14
GCM3:07 pmGeorge Town Owen Roberts Intl
8h 44m
1 stop
CLT11:51 pmCharlotte Douglas
$423
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 22, 2025.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Thu 1/8

7:00 am-1:53 pm

1 stop6h 53m

George Town Owen Roberts Intl

Sun 1/18

2:49 pm-12:40 am

1 stop9h 51m

$275

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Wed 2/4

6:56 pm-1:53 pm

1 stop18h 57m

George Town Owen Roberts Intl

Sun 2/8

2:49 pm-9:47 pm

1 stop6h 58m

$314

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Mon 1/26

5:25 am-12:40 pm

1 stop7h 15m

George Town Owen Roberts Intl

Thu 1/29

2:05 pm-10:07 pm

1 stop8h 02m

$320

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Wed 2/4

6:01 pm-1:53 pm

2 stops19h 52m

George Town Owen Roberts Intl

Sun 2/8

2:49 pm-12:40 am

1 stop9h 51m

$327

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sat 12/20

7:00 am-4:55 pm

1 stop9h 55m

George Town Owen Roberts Intl

Sat 12/27

5:56 pm-11:29 pm

1 stop5h 33m

$332

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 2/28

5:27 am-11:00 am

1 stop5h 33m

George Town Owen Roberts Intl

Sat 3/7

3:07 pm-9:04 pm

1 stop5h 57m

$336

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 12/25

6:30 am-4:00 pm

1 stop9h 30m

George Town Owen Roberts Intl

Tue 12/30

2:50 pm-10:35 am

1 stop19h 45m

$352

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 12/25

7:00 am-3:25 pm

1 stop8h 25m

George Town Owen Roberts Intl

Sun 12/28

12:55 pm-8:35 am

1 stop19h 40m

$366

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Mon 1/26

7:42 pm-11:26 am

1 stop15h 44m

George Town Owen Roberts Intl

Thu 1/29

8:50 am-11:58 pm

1 stop15h 08m

$380

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Thu 1/22

10:10 am-1:45 pm

1 stop27h 35m

George Town Owen Roberts Intl

Mon 1/26

2:25 pm-10:46 pm

1 stop8h 21m

$524

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to the Cayman Islands from

How to get the cheapest flight ticket from South Carolina to Cayman Islands

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Cayman Islands?

If you aren’t able to travel to Cayman Islands during the month of January, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $496.

What is the cheapest day to depart on your flight to Cayman Islands?

Our data shows that Wednesday is the least expensive day to fly to Cayman Islands. Tickets to fly out on this day can be as low as $488. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Cayman Islands on Saturday is $716.

Cheap South Carolina to Cayman Islands flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Cayman Islands

Fastest flight time

2h 50m

Direct flights

Every day

Airports in Cayman Islands

1 airport
The fastest flight from South Carolina to Cayman Islands takes 2h 50m
Direct flights go from South Carolina to Cayman Islands every day.
There is 1 airport near Cayman Islands: George Town Owen Roberts Intl (GCM)
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Cayman Islands?

    Prices for flights from South Carolina to Cayman Islands are refreshed on a daily basis.

  • How many operators does momondo search for flights from South Carolina to Cayman Islands?

  • How old do you have to be to fly from South Carolina to Cayman Islands?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Cayman Islands.

  • What documentation or ID do you need to fly to Cayman Islands?

    The travel and health documents you'll need for your trip to Cayman Islands may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Cayman Islands. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Cayman Islands

Compare and see reviews for airlines that fly from South Carolina to Cayman Islands with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $428Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights
DeltaPriceFrom $555Free CancellationRating
7.9
8,002 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Cayman Islands?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Cayman Islands. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Cayman Islands with flexible booking policies on momondo?

momondo does allow users to show only those flights to Cayman Islands from South Carolina which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from South Carolina to Cayman Islands?

momondo provides multiple filters to help you find the best flight to Cayman Islands from South Carolina. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from South Carolina to Cayman Islands right now. Can momondo alert me if prices change?

Price alerts on flights to Cayman Islands from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Find better results for your trip to the Cayman Islands

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