What is the cheapest airline that flies from South Carolina to Cayman Islands?

Delta, American Airlines, and United Airlines are the most popular carriers operating from South Carolina to Cayman Islands

How long is the flight from South Carolina to Cayman Islands?

Flight times vary depending on what airport in South Carolina you fly out of and what airport in Cayman Islands you fly into. For example, flying from Columbia to George Town takes 6h 19m on average. On the other hand, flying from Greenville to George Town takes 7h 08m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.

When did momondo last update prices for flights from South Carolina to Cayman Islands?

Prices for flights from South Carolina to Cayman Islands are refreshed on a daily basis.

How many operators does momondo search for flights from South Carolina to Cayman Islands?

As of October 2026, there are 2 operators available to choose from for flights from South Carolina to Cayman Islands.

How old do you have to be to fly from South Carolina to Cayman Islands?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Cayman Islands.

What documentation or ID do you need to fly to Cayman Islands?

The travel and health documents you'll need for your trip to Cayman Islands may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Cayman Islands. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$266 Cheap Flights from South Carolina to the Cayman Islands in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to the Cayman Islands

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:00 am - 2:45 pmCHS Charleston-GCM George Town Owen Roberts Intl

7h 45m1 stop Miami

12:59 pm - 6:33 pmGCM George Town Owen Roberts Intl-CHS Charleston

5h 34m1 stop Charlotte Douglas

$565American Airlines

Tue, Dec 8 - Wed, Jan 13

6:57 am - 8:01 pmCHS Charleston-GCM George Town Owen Roberts Intl

13h 04m2 stops New York LaGuardia Miami

12:48 pm - 11:07 pmGCM George Town Owen Roberts Intl-CHS Charleston

10h 19m2 stops Miami Charlotte Douglas

$570American Airlines

Tue, Dec 8 - Wed, Jan 13

6:02 am - 11:26 amCHS Charleston-GCM George Town Owen Roberts Intl

5h 24m1 stop Charlotte Douglas

12:48 pm - 11:07 pmGCM George Town Owen Roberts Intl-CHS Charleston

10h 19m2 stops Miami Charlotte Douglas

$570American Airlines

Tue, Dec 8 - Wed, Jan 13

7:04 am - 11:55 amCHS Charleston-GCM George Town Owen Roberts Intl

4h 51m1 stop Miami

12:18 pm - 6:46 pmGCM George Town Owen Roberts Intl-CHS Charleston

6h 28m1 stop Charlotte Douglas

$570American Airlines

Wed, Nov 11 - Wed, Nov 18

6:00 am - 7:53 pmCHS Charleston-GCM George Town Owen Roberts Intl

13h 53m2 stops Philadelphia Miami

3:45 pm - 10:02 pmGCM George Town Owen Roberts Intl-CHS Charleston

6h 17m1 stop Miami

$575American Airlines

Wed, Nov 11 - Wed, Nov 18

10:12 am - 5:20 pmGSP Greenville-GCM George Town Owen Roberts Intl

7h 08m1 stop Tampa

3:35 pm - 8:07 pmGCM George Town Owen Roberts Intl-GSP Greenville

52h 32m2 stops Toronto Pearson Intl Tampa

$581Multiple Airlines

Thu, Nov 12 - Thu, Nov 19

10:10 am - 4:35 pmGSP Greenville-GCM George Town Owen Roberts Intl

6h 25m1 stop Washington, D.C. Dulles Intl

2:55 pm - 9:33 amGCM George Town Owen Roberts Intl-GSP Greenville

18h 38m1 stop Chicago O'Hare Intl

$639United Airlines

Tue, Dec 22 - Mon, Dec 28

6:25 pm - 4:05 pmMYR Myrtle Beach Intl-GCM George Town Owen Roberts Intl

21h 40m1 stop Tampa

12:40 pm - 11:44 amGCM George Town Owen Roberts Intl-MYR Myrtle Beach Intl

23h 04m1 stop Tampa

$641Multiple Airlines

Thu, Nov 12 - Thu, Nov 19

6:49 am - 4:30 pmGSP Greenville-GCM George Town Owen Roberts Intl

9h 41m1 stop Houston George Bush Intcntl

5:45 pm - 9:59 pmGCM George Town Owen Roberts Intl-GSP Greenville

28h 14m1 stop Houston George Bush Intcntl

$642United Airlines

Thu, Nov 12 - Tue, Nov 17

6:34 pm - 11:58 amGSP Greenville-GCM George Town Owen Roberts Intl

17h 24m1 stop Detroit Metropolitan Wayne County

3:54 pm - 9:37 pmGCM George Town Owen Roberts Intl-GSP Greenville

5h 43m1 stop Atlanta Hartsfield-Jackson

$687Delta

Mon, Dec 21 - Sat, Dec 26

Cheap last minute flights

Enter your travel dates to find the best prices.

8:30 pm - 11:30 amMYR Myrtle Beach Intl-GCM George Town Owen Roberts Intl

16h 00m1 stop Charlotte Douglas

12:35 pm - 10:02 pmGCM George Town Owen Roberts Intl-MYR Myrtle Beach Intl

8h 27m1 stop Charlotte Douglas

$826American Airlines

Sun, Oct 4 - Sun, Oct 11

6:15 pm - 1:10 pmMYR Myrtle Beach Intl-GCM George Town Owen Roberts Intl

19h 55m2 stops Charlotte Douglas Miami

8:00 am - 10:02 pmGCM George Town Owen Roberts Intl-MYR Myrtle Beach Intl

13h 02m2 stops Miami Charlotte Douglas

$831American Airlines

Sun, Oct 4 - Sun, Oct 11

6:15 pm - 1:10 pmMYR Myrtle Beach Intl-GCM George Town Owen Roberts Intl

19h 55m2 stops Charlotte Douglas Miami

12:35 pm - 10:02 pmGCM George Town Owen Roberts Intl-MYR Myrtle Beach Intl

8h 27m1 stop Charlotte Douglas

$831American Airlines

Sun, Oct 4 - Sun, Oct 11

8:30 pm - 11:30 amMYR Myrtle Beach Intl-GCM George Town Owen Roberts Intl

16h 00m1 stop Charlotte Douglas

12:35 pm - 10:02 pmGCM George Town Owen Roberts Intl-MYR Myrtle Beach Intl

8h 27m1 stop Charlotte Douglas

$906American Airlines

Sun, Oct 4 - Sun, Oct 11

8:30 pm - 11:30 amMYR Myrtle Beach Intl-GCM George Town Owen Roberts Intl

16h 00m1 stop Charlotte Douglas

8:00 am - 7:30 pmGCM George Town Owen Roberts Intl-MYR Myrtle Beach Intl

10h 30m2 stops Miami Washington, D.C. Reagan-National

$911American Airlines

Sun, Oct 4 - Sun, Oct 11

6:15 pm - 1:10 pmMYR Myrtle Beach Intl-GCM George Town Owen Roberts Intl

19h 55m2 stops Charlotte Douglas Miami

12:35 pm - 10:02 pmGCM George Town Owen Roberts Intl-MYR Myrtle Beach Intl

8h 27m1 stop Charlotte Douglas

$911American Airlines

Sun, Oct 4 - Sun, Oct 11

6:15 pm - 1:10 pmMYR Myrtle Beach Intl-GCM George Town Owen Roberts Intl

19h 55m2 stops Charlotte Douglas Miami

8:00 am - 10:02 pmGCM George Town Owen Roberts Intl-MYR Myrtle Beach Intl

13h 02m2 stops Miami Charlotte Douglas

$911American Airlines

Sun, Oct 4 - Sun, Oct 11

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Delta flights from South Carolina to Cayman Islands

Our best Delta deals on South Carolina to Cayman Islands flight tickets

Delta

Dec 21

GSP6:34 pmGreenville

17h 24m

1 stop

GCM11:58 amGeorge Town Owen Roberts Intl

Dec 26

GCM3:54 pmGeorge Town Owen Roberts Intl

5h 43m

1 stop

GSP9:37 pmGreenville

$687

Delta

Dec 21

GSP8:00 amGreenville

6h 36m

1 stop

GCM2:36 pmGeorge Town Owen Roberts Intl

Dec 23

GCM3:51 pmGeorge Town Owen Roberts Intl

8h 08m

1 stop

GSP11:59 pmGreenville

$836

Delta

Dec 20

GSP10:04 amGreenville

4h 32m

1 stop

GCM2:36 pmGeorge Town Owen Roberts Intl

Dec 26

GCM3:54 pmGeorge Town Owen Roberts Intl

5h 43m

1 stop

GSP9:37 pmGreenville

$885

American Airlines flights from South Carolina to Cayman Islands

Our best American Airlines deals on South Carolina to Cayman Islands flight tickets

American Airlines

Dec 8

CHS7:00 amCharleston

7h 45m

1 stop

GCM2:45 pmGeorge Town Owen Roberts Intl

Jan 13

GCM12:59 pmGeorge Town Owen Roberts Intl

5h 34m

1 stop

CHS6:33 pmCharleston

$565

American Airlines

Dec 8

CHS6:57 amCharleston

13h 04m

2 stops

GCM8:01 pmGeorge Town Owen Roberts Intl

Jan 13

GCM12:48 pmGeorge Town Owen Roberts Intl

10h 19m

2 stops

CHS11:07 pmCharleston

$570

American Airlines

Nov 11

CHS6:00 amCharleston

13h 53m

2 stops

GCM7:53 pmGeorge Town Owen Roberts Intl

Nov 18

GCM3:45 pmGeorge Town Owen Roberts Intl

6h 17m

1 stop

CHS10:02 pmCharleston

$575

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonGeorge Town

CHS Charleston - GCM George Town Owen Roberts Intl

CHSGCM

Charleston

Tue 12/8

7:00 am-2:45 pm

1 stop7h 45m

George Town Owen Roberts Intl

Wed 1/13

12:59 pm-6:33 pm

1 stop5h 34m

$565

CharlestonGeorge Town

CHS Charleston - GCM George Town Owen Roberts Intl

CHSGCM

Charleston

Tue 12/8

6:57 am-8:01 pm

2 stops13h 04m

George Town Owen Roberts Intl

Wed 1/13

12:48 pm-11:07 pm

2 stops10h 19m

$570

CharlestonGeorge Town

CHS Charleston - GCM George Town Owen Roberts Intl

CHSGCM

Charleston

Tue 12/8

6:02 am-11:26 am

1 stop5h 24m

George Town Owen Roberts Intl

Wed 1/13

12:48 pm-11:07 pm

2 stops10h 19m

$570

Quickest round-trip

CharlestonGeorge Town

CHS Charleston - GCM George Town Owen Roberts Intl

CHSGCM

Charleston

Wed 11/11

7:04 am-11:55 am

1 stop4h 51m

George Town Owen Roberts Intl

Wed 11/18

12:18 pm-6:46 pm

1 stop6h 28m

$570

CharlestonGeorge Town

CHS Charleston - GCM George Town Owen Roberts Intl

CHSGCM

Charleston

Wed 11/11

6:00 am-7:53 pm

2 stops13h 53m

George Town Owen Roberts Intl

Wed 11/18

3:45 pm-10:02 pm

1 stop6h 17m

$575

GreenvilleGeorge Town

GSP Greenville - GCM George Town Owen Roberts Intl

GSPGCM

Greenville

Thu 11/12

10:12 am-5:20 pm

1 stop7h 08m

George Town Owen Roberts Intl

Thu 11/19

3:35 pm-8:07 pm

2 stops52h 32m

$581

GreenvilleGeorge Town

GSP Greenville - GCM George Town Owen Roberts Intl

GSPGCM

Greenville

Tue 12/22

10:10 am-4:35 pm

1 stop6h 25m

George Town Owen Roberts Intl

Mon 12/28

2:55 pm-9:33 am

1 stop18h 38m

$639

Myrtle BeachGeorge Town

MYR Myrtle Beach Intl - GCM George Town Owen Roberts Intl

MYRGCM

Myrtle Beach Intl

Thu 11/12

6:25 pm-4:05 pm

1 stop21h 40m

George Town Owen Roberts Intl

Thu 11/19

12:40 pm-11:44 am

1 stop23h 04m

$641

GreenvilleGeorge Town

GSP Greenville - GCM George Town Owen Roberts Intl

GSPGCM

Greenville

Thu 11/12

6:49 am-4:30 pm

1 stop9h 41m

George Town Owen Roberts Intl

Tue 11/17

5:45 pm-9:59 pm

1 stop28h 14m

$642

GreenvilleGeorge Town

GSP Greenville - GCM George Town Owen Roberts Intl

GSPGCM

Greenville

Mon 12/21

6:34 pm-11:58 am

1 stop17h 24m

George Town Owen Roberts Intl

Sat 12/26

3:54 pm-9:37 pm

1 stop5h 43m

$687

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Cayman Islands

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Cayman Islands?

If you aren’t able to travel to Cayman Islands during the month of January, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $414.

Cheap South Carolina to Cayman Islands flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Cayman Islands

Best Price Found	$266
Fastest flight time	2h 53m
Direct flights	None

The best one-way flight to Cayman Islands from South Carolina in the past 72 hours is $266. The best round-trip flight deal from South Carolina to Cayman Islands found on momondo in the last 72 hours is $565.

The fastest flight from South Carolina to Cayman Islands takes 2h 53m

There are no direct flights from South Carolina to Cayman Islands. There are no popular flight routes from South Carolina to Cayman Islands.

Search flight deals

Frequently asked questions about flying from South Carolina to the Cayman Islands

When did momondo last update prices for flights from South Carolina to Cayman Islands?
Prices for flights from South Carolina to Cayman Islands are refreshed on a daily basis.
How many operators does momondo search for flights from South Carolina to Cayman Islands?
As of October 2026, there are 2 operators available to choose from for flights from South Carolina to Cayman Islands.
How old do you have to be to fly from South Carolina to Cayman Islands?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Cayman Islands.
What documentation or ID do you need to fly to Cayman Islands?
The travel and health documents you'll need for your trip to Cayman Islands may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Cayman Islands. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Cayman Islands

Compare and see reviews for airlines that fly from South Carolina to Cayman Islands with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $287	Free Cancellation	Rating 7.8 8,615 reviews		Search Delta flights
American Airlines	PriceFrom $289	Free Cancellation	Rating 7.0 12,101 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Cayman Islands?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Cayman Islands. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Cayman Islands with flexible booking policies on momondo?

momondo does allow users to show only those flights to Cayman Islands from South Carolina which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from South Carolina to Cayman Islands?

momondo provides multiple filters to help you find the best flight to Cayman Islands from South Carolina. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from South Carolina to Cayman Islands right now. Can momondo alert me if prices change?

Price alerts on flights to Cayman Islands from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Cayman Islands trip

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Popular cities in the Cayman Islands

Flights to George Townfrom $78

Flights to Cayman Bracfrom $313

Flights to Little Caymanfrom $376

Cheap flights from South Carolina to the Cayman Islands from $266

Find the cheapest flights from South Carolina to the Cayman Islands

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Delta flights from South Carolina to Cayman Islands

Our best Delta deals on South Carolina to Cayman Islands flight tickets

American Airlines flights from South Carolina to Cayman Islands

Our best American Airlines deals on South Carolina to Cayman Islands flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.

See travel insights to the Cayman Islands from

How to get the cheapest flight ticket from South Carolina to Cayman Islands

What is the cheapest month to fly to Cayman Islands?

What is the cheapest airline that flies from South Carolina to Cayman Islands?

How long is the flight from South Carolina to Cayman Islands?

Cheap South Carolina to Cayman Islands flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from South Carolina to the Cayman Islands

Best airlines flying from South Carolina to Cayman Islands

Compare and see reviews for airlines that fly from South Carolina to Cayman Islands with momondo

Why use momondo?

An easier way to manage your Cayman Islands trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the Cayman Islands

Popular cities in the Cayman Islands

Popular flights according to clicks in the last 7 days on momondo

South Carolina flight routes

According to popular flight searches on momondo this year

Cayman Islands flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to the Cayman Islands

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to the Cayman Islands

List of cabin classes available on flights landing in the Cayman Islands. Availability may vary depending on flight origin and airline.

Complete your trip to the Cayman Islands

Explore popular destinations other users love

According to popular flight searches on momondo this year