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Cheap flights from Santo Domingo to Medellín from $100

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santo Domingo to Medellín departing on 10/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Arajet Logo
7:07 pm - 8:42 pmSDQ-MDE
2h 35mnonstop
Arajet Logo
8:25 pm - 11:57 pmMDE-SDQ
2h 32mnonstop
$209Arajet
Find Deal
Fri, Oct 24 - Wed, Oct 29
Arajet Logo
8:00 am - 9:32 amSDQ-MDE
2h 32mnonstop
Arajet Logo
10:05 am - 1:37 pmMDE-SDQ
2h 32mnonstop
$210Arajet
Find Deal
Tue, Nov 25 - Sat, Nov 29
Arajet Logo
9:40 am - 11:15 amSDQ-MDE
2h 35mnonstop
Arajet Logo
9:27 pm - 12:59 amMDE-SDQ
2h 32mnonstop
$211Arajet
Find Deal
Mon, Oct 20 - Fri, Oct 24
Wingo Logo
2:33 pm - 4:01 pmSDQ-MDE
2h 28mnonstop
Wingo Logo
10:24 am - 1:57 pmMDE-SDQ
2h 33mnonstop
$224Wingo
Find Deal
Sat, Oct 25 - Sat, Nov 1
Wingo Logo
2:33 pm - 4:01 pmSDQ-MDE
2h 28mnonstop
Wingo Logo
10:13 am - 1:43 pmMDE-SDQ
2h 30mnonstop
$227Wingo
Find Deal
Sat, Oct 4 - Sat, Oct 11
Multiple Airlines Logo
9:10 am - 3:00 pmSDQ-MDE
6h 50m1 stop
Multiple Airlines Logo
10:17 am - 1:49 pmMDE-SDQ
2h 32mnonstop
$256Multiple Airlines
Find Deal
Fri, Oct 31 - Tue, Nov 4
Multiple Airlines Logo
9:10 am - 3:00 pmSDQ-MDE
6h 50m1 stop
Multiple Airlines Logo
2:23 pm - 9:40 pmMDE-SDQ
6h 17m1 stop
$259Multiple Airlines
Find Deal
Fri, Oct 31 - Tue, Nov 4
Copa Airlines Logo
8:58 am - 1:25 pmSDQ-MDE
5h 27m1 stop
Copa Airlines Logo
10:46 am - 10:25 pmMDE-SDQ
10h 39m1 stop
$265Copa Airlines
Find Deal
Mon, Oct 20 - Fri, Oct 24
Copa Airlines Logo
8:58 am - 2:15 pmSDQ-MDE
6h 17m1 stop
Copa Airlines Logo
12:42 pm - 2:26 amMDE-SDQ
12h 44m1 stop
$266Copa Airlines
Find Deal
Wed, Oct 29 - Mon, Nov 3
Avianca Logo
11:45 am - 6:49 pmSDQ-MDE
8h 04m1 stop
Avianca Logo
8:53 am - 5:15 pmMDE-SDQ
7h 22m1 stop
$274Avianca
Find Deal
Thu, Oct 9 - Sun, Oct 12

Avianca flights from Santo Domingo to Medellín Jose Maria Cordova Intl Airport

Our best Avianca deals on Santo Domingo to Medellín Jose Maria Cordova Intl Airport flight tickets
Avianca
Oct 9
SDQ11:45 amSanto Domingo Las Americas
8h 04m
1 stop
MDE6:49 pmMedellín Jose Maria Cordova Intl
Oct 12
MDE8:53 amMedellín Jose Maria Cordova Intl
7h 22m
1 stop
SDQ5:15 pmSanto Domingo Las Americas
$274
Find similar
Avianca
Sep 17
SDQ6:10 pmSanto Domingo Las Americas
13h 04m
1 stop
MDE6:14 amMedellín Jose Maria Cordova Intl
Sep 22
MDE8:52 pmMedellín Jose Maria Cordova Intl
12h 58m
1 stop
SDQ10:50 amSanto Domingo Las Americas
$341
Find similar
Avianca
Sep 20
SDQ11:45 amSanto Domingo Las Americas
5h 27m
1 stop
MDE4:12 pmMedellín Jose Maria Cordova Intl
Sep 24
MDE9:18 amMedellín Jose Maria Cordova Intl
6h 57m
1 stop
SDQ5:15 pmSanto Domingo Las Americas
$381
Find similar

Arajet flights from Santo Domingo to Medellín Jose Maria Cordova Intl Airport

Our best Arajet deals on Santo Domingo to Medellín Jose Maria Cordova Intl Airport flight tickets
Arajet
Oct 24
SDQ7:07 pmSanto Domingo Las Americas
2h 35m
MDE8:42 pmMedellín Jose Maria Cordova Intl
Oct 29
MDE8:25 pmMedellín Jose Maria Cordova Intl
2h 32m
SDQ11:57 pmSanto Domingo Las Americas
$209
Find similar
Arajet
Nov 25
SDQ8:00 amSanto Domingo Las Americas
2h 32m
MDE9:32 amMedellín Jose Maria Cordova Intl
Nov 29
MDE10:05 amMedellín Jose Maria Cordova Intl
2h 32m
SDQ1:37 pmSanto Domingo Las Americas
$210
Find similar
Arajet
Oct 20
SDQ9:40 amSanto Domingo Las Americas
2h 35m
MDE11:15 amMedellín Jose Maria Cordova Intl
Oct 24
MDE9:27 pmMedellín Jose Maria Cordova Intl
2h 32m
SDQ12:59 amSanto Domingo Las Americas
$211
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Medellín Jose Maria Cordova Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Santo Domingo to Medellín Jose Maria Cordova Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Fri 10/24

7:07 pm-8:42 pm

Nonstop2h 35m

Medellín Jose Maria Cordova Intl

Wed 10/29

8:25 pm-11:57 pm

Nonstop2h 32m

$209

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Tue 11/25

8:00 am-9:32 am

Nonstop2h 32m

Medellín Jose Maria Cordova Intl

Sat 11/29

10:05 am-1:37 pm

Nonstop2h 32m

$210

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Mon 10/20

9:40 am-11:15 am

Nonstop2h 35m

Medellín Jose Maria Cordova Intl

Fri 10/24

9:27 pm-12:59 am

Nonstop2h 32m

$211

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Sat 10/25

2:33 pm-4:01 pm

Nonstop2h 28m

Medellín Jose Maria Cordova Intl

Sat 11/1

10:24 am-1:57 pm

Nonstop2h 33m

$224

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Sat 10/4

2:33 pm-4:01 pm

Nonstop2h 28m

Medellín Jose Maria Cordova Intl

Sat 10/11

10:13 am-1:43 pm

Nonstop2h 30m

$227

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Fri 10/31

9:10 am-3:00 pm

1 stop6h 50m

Medellín Jose Maria Cordova Intl

Tue 11/4

10:17 am-1:49 pm

Nonstop2h 32m

$256

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Fri 10/31

9:10 am-3:00 pm

1 stop6h 50m

Medellín Jose Maria Cordova Intl

Tue 11/4

2:23 pm-9:40 pm

1 stop6h 17m

$259

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Mon 10/20

8:58 am-1:25 pm

1 stop5h 27m

Medellín Jose Maria Cordova Intl

Fri 10/24

10:46 am-10:25 pm

1 stop10h 39m

$265

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Wed 10/29

8:58 am-2:15 pm

1 stop6h 17m

Medellín Jose Maria Cordova Intl

Mon 11/3

12:42 pm-2:26 am

1 stop12h 44m

$266

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Thu 10/9

11:45 am-6:49 pm

1 stop8h 04m

Medellín Jose Maria Cordova Intl

Sun 10/12

8:53 am-5:15 pm

1 stop7h 22m

$274

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Santo Domingo to Medellín Jose Maria Cordova Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Medellín Jose Maria Cordova Intl Airport?

In general, February is the cheapest month to fly from Santo Domingo to Medellín Jose Maria Cordova Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $242. If you aren’t able to travel during the month of February, then book flights to Medellín Jose Maria Cordova Intl Airport from Santo Domingo during March instead. Flights to Medellín Jose Maria Cordova Intl Airport in March, while not as cheap as those in February, still average around $246.

What is the cheapest day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

The cheapest day to depart from Santo Domingo to Medellín Jose Maria Cordova Intl Airport is on a Monday. Travelers who choose to depart for Medellín Jose Maria Cordova Intl Airport on a Monday will often find tickets for as low as $251. On the other hand, Friday is the most expensive day to depart from Santo Domingo because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $298.

What is the cheapest time of day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

Our data shows that the cheapest Santo Domingo to Medellín Jose Maria Cordova Intl Airport flights are usually those with departure times at noon. Our users have found flights to Medellín Jose Maria Cordova Intl Airport at noon for as low as $256. In contrast, the most expensive time of day to depart to Medellín Jose Maria Cordova Intl Airport is in the evening when prices are around $281.

What is the cheapest Santo Domingo Las Americas to Medellín Jose Maria Cordova Intl flight route?

Fly from Santo Domingo Las Americas to Medellín Jose Maria Cordova Intl for the best Santo Domingo Las Americas - Medellín Jose Maria Cordova Intl flight prices

How far in advance should I book a flight to Medellín Jose Maria Cordova Intl Airport?

You are more likely to see cheaper flights to Medellín Jose Maria Cordova Intl Airport from Santo Domingo when booking weeks ahead of your departure date. In general, you can expect to find flights to Medellín Jose Maria Cordova Intl Airport for around $265 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Medellín Jose Maria Cordova Intl Airport from Santo Domingo for as low as $242 on momondo.

What cabin class options are available on Santo Domingo Las Americas to Medellín Jose Maria Cordova Intl flights?

There are 2 cabin classes available to choose from on Santo Domingo Las Americas to Medellín Jose Maria Cordova Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Santo Domingo to Medellín Jose Maria Cordova Intl Airport flight prices changed over time?

As of September 2025, prices for Santo Domingo to Medellín Jose Maria Cordova Intl Airport flights are approximately 37% more expensive when compared to flights at the same time last year.

When to book flights from Santo Domingo to Medellín Jose Maria Cordova Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Santo Domingo to Medellín Jose Maria Cordova Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santo Domingo to Medellín Jose Maria Cordova Intl Airport (SDQ to MDE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to Medellín Jose Maria Cordova Intl Airport

Best Price Found

$125

Fastest flight time

2h 28m

Direct flights

Every day
The best one-way flight to Medellín Jose Maria Cordova Intl Airport from Santo Domingo in the past 72 hours is $125. The best round-trip flight deal from Santo Domingo to Medellín Jose Maria Cordova Intl Airport found on momondo in the last 72 hours is $230.
The fastest flight from Santo Domingo to Medellín Jose Maria Cordova Intl Airport takes 2h 28m
Direct flights go from Santo Domingo to Medellín Jose Maria Cordova Intl Airport every day.
Search flight deals

  • How far is Santo Domingo Las Americas to Medellín Jose Maria Cordova Intl by plane?

    The straight-line distance from Santo Domingo Las Americas to Medellín Jose Maria Cordova Intl is 927.5 mi. By plane, this route typically takes 2h 28m.

  • When did momondo last update prices for flights from Santo Domingo Las Americas Airport to Medellín Jose Maria Cordova Intl Airport?

    Prices for flights from Santo Domingo Las Americas Airport to Medellín Jose Maria Cordova Intl Airport refresh daily.

  • How many operators does momondo search for flights from Santo Domingo Las Americas Airport to Medellín Jose Maria Cordova Intl Airport?

  • How old do you have to be to fly from Santo Domingo Las Americas Airport to Medellín Jose Maria Cordova Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santo Domingo Las Americas Airport to Medellín Jose Maria Cordova Intl Airport.

  • What documentation or ID do you need to fly to Medellín Jose Maria Cordova Intl Airport?

    The necessary travel and health documents for your Medellín Jose Maria Cordova Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santo Domingo to Medellín Jose Maria Cordova Intl Airport?

  • What is the most popular airline from Santo Domingo to Medellín Jose Maria Cordova Intl Airport?

Best airlines flying from Santo Domingo to Medellín Jose Maria Cordova Intl Airport

Compare and see reviews for airlines that fly from Santo Domingo to Medellín Jose Maria Cordova Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
WingoPriceFrom $115Free CancellationRating
7.3
136 reviews
Search Wingo flights
Copa AirlinesPriceFrom $176Free CancellationRating
7.6
1,531 reviews
Search Copa Airlines flights
ArajetPriceFrom $198Free CancellationRating
7.0
34 reviews
Search Arajet flights
AviancaPriceFrom $238Free CancellationRating
6.7
2,435 reviews
Search Avianca flights

  • Wingo Flights From Santo Domingo to Medellín Jose Maria Cordova Intl Airport

    The lowest priced Wingo flight from Santo Domingo to Medellín Jose Maria Cordova Intl Airport from the last 72 hours was $115. Generally, Wingo has 1 flight on this route every week with an average price of $257. Wingo is rated 7.3/10 by our users.

  • Arajet Flights From Santo Domingo to Medellín Jose Maria Cordova Intl Airport

    Arajet (7.0/10 from 34 reviews) operates around 3 flights from Santo Domingo to Medellín Jose Maria Cordova Intl Airport in any given week. The average Arajet airfare for this route is around $278, with deals from around $198 rare but found on momondo. Referenced prices are for round-trip Santo Domingo to Medellín Jose Maria Cordova Intl Airport flight searches in the last 72 hours.

Traveling to a place near Medellín?

Book flights to Medellín if you plan to visit one of these locations
Guatapé
Rionegro

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to Medellín?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Medellín from Santo Domingo.

Can I find flights from Santo Domingo to Medellín with flexible booking policies on momondo?

Yes. All flights to Medellín from Santo Domingo on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santo Domingo to Medellín?

Once you have performed a search for Santo Domingo to Medellín flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santo Domingo to Medellín right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santo Domingo to Medellín now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Medellín and let you know when they change.

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