Cheap flights from Santiago to Mexico City from $315

The cheapest month to fly to Mexico City Benito Juarez Airport from Santiago is in March. Flight prices, which tend to average around $579, are often lower during this time because this is during the off-season. If you don’t want to visit Mexico City Benito Juarez Airport in March, then you should wait until February to fly from Santiago, when ticket prices are also cheap, with an average price of $631.

The cheapest day to depart from Santiago to Mexico City Benito Juarez Airport is on a Monday. Travelers who choose to depart for Mexico City Benito Juarez Airport on a Monday will often find tickets for as low as $580. Flights from Santiago to Mexico City Benito Juarez Airport on a Saturday will generally be more expensive and average around $959. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

According to our data, the cheapest time of day to fly to Mexico City Benito Juarez Airport is in the evening. momondo users have found flights departing from Santiago to Mexico City Benito Juarez Airport in the evening for as low as $683. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the morning is when there is more demand to fly to Mexico City Benito Juarez Airport, so prices are often more expensive at around $791 per ticket.

Fly from Santiago Arturo Merino Benitez to Mexico City Benito Juarez for the best Santiago Arturo Merino Benitez - Mexico City Benito Juarez flight prices

You are more likely to see cheaper flights to Mexico City Benito Juarez Airport from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Mexico City Benito Juarez Airport for around $689 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Mexico City Benito Juarez Airport from Santiago for as low as $579 on momondo.

There are 4 cabin classes available to choose from on Santiago to Mexico City Benito Juarez Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

LATAM Airlines and Copa Airlines are the most popular carriers operating from Santiago Arturo Merino Benitez to Mexico City Benito Juarez

LATAM Airlines, Aeromexico and Copa Airlines are the top three most popular airlines that fly to Mexico City Benito Juarez Airport from Santiago according to our data. LATAM Airlines is the first choice among our users, with 80% of people opting to fly with this airline when traveling to Mexico City Benito Juarez Airport. Keep in mind that there are 3 different airlines that fly to Mexico City Benito Juarez Airport on a routine basis, so you have a few additional options to choose from.

Historically, on average around 10% of flights between Santiago and Mexico City have experienced a delay on any given week. The average delay length over the past 12 months has been 146 minutes.

Generally, flights departing at night tend to experience fewer delays. Flights in the morning have, in the past, seen delays more frequently in comparison.

Friday is statistically the day of the week which experiences the fewest number of delays on this flight route. Sunday has historically seen more delays on average compared to the rest of the week.

According to our data, Aeromexico have had the least number of delays on this route over the last 12 months; with about 8% of their flights experiencing any sort of delay.

Panama City (PTY) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Flights via Panama City (PTY) offer the lowest average round-trip price of $663.

Flights connecting via Panama City (PTY) have the shortest average one-way travel time: 11h 44m.

Panama City (PTY) has the shortest average layover time for this route: 1h 13m.

As of October 2026, there are 1 flights per day flying from Santiago to Mexico City Benito Juarez Airport. The most common time of day flights depart is 9:00AM, with 100% of flights taking off at noon.

As of October 2026, there are 11 flights per week flying from Santiago to Mexico City Benito Juarez Airport. The most common day of the week flights depart is Wed, with 27% of flights taking off on this day.