Cheap flights from Santiago to Mexico City from $271

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Mexico City departing on 12/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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Avianca Logo
7:25 am - 6:10 pmSCL-MEX
13h 45m1 stop
Avianca Logo
12:40 am - 3:20 pmMEX-SCL
11h 40m1 stop
$487Avianca
Find Deal
Thu, Feb 26 - Fri, Mar 13
Copa Airlines Logo
3:32 am - 7:20 pmSCL-MEX
18h 48m1 stop
Copa Airlines Logo
1:10 pm - 3:58 amMEX-SCL
11h 48m1 stop
$493Copa Airlines
Find Deal
Tue, Mar 10 - Tue, Mar 24
LATAM Airlines Logo
9:10 am - 2:50 pmSCL-MEX
8h 40mnonstop
LATAM Airlines Logo
7:50 pm - 7:30 amMEX-SCL
8h 40mnonstop
$508LATAM Airlines
Find Deal
Wed, Nov 26 - Wed, Dec 3
LATAM Airlines Logo
4:35 am - 1:50 pmSCL-MEX
12h 15m1 stop
LATAM Airlines Logo
7:50 pm - 7:30 amMEX-SCL
8h 40mnonstop
$514LATAM Airlines
Find Deal
Sun, Mar 1 - Thu, Mar 12
Copa Airlines Logo
5:44 am - 12:15 amSCL-MEX
21h 31m1 stop
Copa Airlines Logo
1:20 am - 12:34 amMEX-SCL
20h 14m1 stop
$517Copa Airlines
Find Deal
Sat, Mar 7 - Wed, Mar 25
Copa Airlines Logo
4:20 am - 12:15 amSCL-MEX
21h 55m1 stop
Copa Airlines Logo
1:40 am - 10:43 pmMEX-SCL
19h 03m1 stop
$522Copa Airlines
Find Deal
Wed, Apr 8 - Mon, Apr 13
Copa Airlines Logo
5:24 am - 12:15 amSCL-MEX
21h 51m1 stop
Copa Airlines Logo
5:55 am - 3:27 amMEX-SCL
18h 32m1 stop
$523Copa Airlines
Find Deal
Wed, Nov 19 - Mon, Dec 8
LATAM Airlines Logo
4:35 am - 1:50 pmSCL-MEX
12h 15m1 stop
LATAM Airlines Logo
4:00 pm - 2:45 pmMEX-SCL
19h 45m3 stops
$525LATAM Airlines
Find Deal
Wed, Feb 25 - Sat, Mar 14
Copa Airlines Logo
5:44 am - 1:00 amSCL-MEX
22h 16m1 stop
Copa Airlines Logo
5:55 am - 4:14 amMEX-SCL
19h 19m1 stop
$529Copa Airlines
Find Deal
Fri, Dec 12 - Mon, Jan 5
Avianca Logo
4:25 pm - 3:00 amSCL-MEX
13h 35m1 stop
Avianca Logo
12:40 am - 3:20 pmMEX-SCL
11h 40m1 stop
$577Avianca
Find Deal
Thu, Nov 27 - Tue, Dec 2

Avianca flights from Santiago to Mexico City

Our best Avianca deals on Santiago to Mexico City flight tickets
Avianca
Feb 26
SCL7:25 amSantiago Arturo Merino Benitez
13h 45m
1 stop
MEX6:10 pmMexico City Benito Juarez
Mar 13
MEX12:40 amMexico City Benito Juarez
11h 40m
1 stop
SCL3:20 pmSantiago Arturo Merino Benitez
Avianca
Nov 27
SCL4:25 pmSantiago Arturo Merino Benitez
13h 35m
1 stop
MEX3:00 amMexico City Benito Juarez
Dec 2
MEX12:40 amMexico City Benito Juarez
11h 40m
1 stop
SCL3:20 pmSantiago Arturo Merino Benitez
Avianca
Nov 25
SCL1:35 amSantiago Arturo Merino Benitez
13h 35m
1 stop
MEX12:10 pmMexico City Benito Juarez
Dec 3
MEX11:10 pmMexico City Benito Juarez
13h 10m
1 stop
SCL3:20 pmSantiago Arturo Merino Benitez

Copa Airlines flights from Santiago to Mexico City

Our best Copa Airlines deals on Santiago to Mexico City flight tickets
Copa Airlines
Mar 10
SCL3:32 amSantiago Arturo Merino Benitez
18h 48m
1 stop
MEX7:20 pmMexico City Benito Juarez
Mar 24
MEX1:10 pmMexico City Benito Juarez
11h 48m
1 stop
SCL3:58 amSantiago Arturo Merino Benitez
Copa Airlines
Mar 7
SCL5:44 amSantiago Arturo Merino Benitez
21h 31m
1 stop
MEX12:15 amMexico City Benito Juarez
Mar 25
MEX1:20 amMexico City Benito Juarez
20h 14m
1 stop
SCL12:34 amSantiago Arturo Merino Benitez
Copa Airlines
Apr 8
SCL4:20 amSantiago Arturo Merino Benitez
21h 55m
1 stop
MEX12:15 amMexico City Benito Juarez
Apr 13
MEX1:40 amMexico City Benito Juarez
19h 03m
1 stop
SCL10:43 pmSantiago Arturo Merino Benitez

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 31, 2025.
Use the filters below to find and compare flights from Santiago to Mexico City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Thu 2/26

7:25 am-6:10 pm

1 stop13h 45m

Mexico City Benito Juarez

Fri 3/13

12:40 am-3:20 pm

1 stop11h 40m

$487

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Tue 3/10

3:32 am-7:20 pm

1 stop18h 48m

Mexico City Benito Juarez

Tue 3/24

1:10 pm-3:58 am

1 stop11h 48m

$493

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Wed 11/26

9:10 am-2:50 pm

Nonstop8h 40m

Mexico City Benito Juarez

Wed 12/3

7:50 pm-7:30 am

Nonstop8h 40m

$508

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Sun 3/1

4:35 am-1:50 pm

1 stop12h 15m

Mexico City Benito Juarez

Thu 3/12

7:50 pm-7:30 am

Nonstop8h 40m

$514

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Sat 3/7

5:44 am-12:15 am

1 stop21h 31m

Mexico City Benito Juarez

Wed 3/25

1:20 am-12:34 am

1 stop20h 14m

$517

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Wed 4/8

4:20 am-12:15 am

1 stop21h 55m

Mexico City Benito Juarez

Mon 4/13

1:40 am-10:43 pm

1 stop19h 03m

$522

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Wed 11/19

5:24 am-12:15 am

1 stop21h 51m

Mexico City Benito Juarez

Mon 12/8

5:55 am-3:27 am

1 stop18h 32m

$523

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Wed 2/25

4:35 am-1:50 pm

1 stop12h 15m

Mexico City Benito Juarez

Sat 3/14

4:00 pm-2:45 pm

3 stops19h 45m

$525

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Fri 12/12

5:44 am-1:00 am

1 stop22h 16m

Mexico City Benito Juarez

Mon 1/5

5:55 am-4:14 am

1 stop19h 19m

$529

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Thu 11/27

4:25 pm-3:00 am

1 stop13h 35m

Mexico City Benito Juarez

Tue 12/2

12:40 am-3:20 pm

1 stop11h 40m

$577

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Mexico City from

How to get the cheapest flight ticket from Santiago to Mexico City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Mexico City?

The cheapest month to fly to Mexico City from Santiago is in March. Flight prices, which tend to average around $545, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of March, then book flights to Mexico City from Santiago during May instead. Flights to Mexico City in May, while not as cheap as those in March, still average around $563.

What is the cheapest day to depart on your flight to Mexico City?

Our data shows that Thursday is the least expensive day to fly to Mexico City. Tickets to fly out on this day can be as low as $660. On the other hand, Sunday is the most expensive day to depart from Santiago because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $838.

What is the cheapest time of day to depart on your flight to Mexico City?

According to our data, the cheapest time of day to fly to Mexico City is at noon. momondo users have found flights departing from Santiago to Mexico City at noon for as low as $496. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the morning is when there is more demand to fly to Mexico City, so prices are often more expensive at around $780 per ticket.

What is the cheapest Santiago Arturo Merino Benitez to Mexico City Benito Juarez flight route?

Fly from Santiago Arturo Merino Benitez to Mexico City Benito Juarez for the best Santiago Arturo Merino Benitez - Mexico City Benito Juarez flight prices

How far in advance should I book a flight to Mexico City?

You are more likely to see cheaper flights to Mexico City from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Mexico City for around $604 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Mexico City from Santiago for as low as $535 on momondo.

What cabin class options are available on Santiago Arturo Merino Benitez to Mexico City Benito Juarez flights?

There are 3 cabin classes available to choose from on Santiago Arturo Merino Benitez to Mexico City Benito Juarez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santiago to Mexico City flights?

You could potentially save up to 64% on your flight if you consider stops on a Santiago to Mexico City flight.

How have Santiago to Mexico City flight prices changed over time?

As of October 2025, prices for Santiago to Mexico City flights are approximately 17% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to Mexico City

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Mexico City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Mexico City (SCL to MEX) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Mexico City

Best Price Found

$336

Fastest flight time

8h 25m

Direct flights

Every day

Airports in Mexico City

1 airport
The best one-way flight to Mexico City from Santiago in the past 72 hours is $336. The best round-trip flight deal from Santiago to Mexico City found on momondo in the last 72 hours is $588.
The fastest flight from Santiago to Mexico City takes 8h 25m
Direct flights go from Santiago to Mexico City every day.
There is 1 airport near Mexico City: Mexico City Benito Juarez (MEX)
  • How far is Santiago Arturo Merino Benitez to Mexico City Benito Juarez by plane?

    There are 4104.7 mi between Santiago Arturo Merino Benitez and Mexico City Benito Juarez. By plane, this route typically takes 8h 40m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Mexico City Benito Juarez Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Mexico City Benito Juarez Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Mexico City Benito Juarez Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Mexico City Benito Juarez Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Mexico City Benito Juarez Airport.

  • What documentation or ID do you need to fly to Mexico City Benito Juarez Airport?

    The travel and health documents you'll need for your trip to Mexico City Benito Juarez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Mexico City Benito Juarez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santiago to Mexico City?

  • What is the most popular airline from Santiago to Mexico City?

Best airlines flying from Santiago to Mexico City

Compare and see reviews for airlines that fly from Santiago to Mexico City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $237Free CancellationRating
7.6
1,561 reviews
Search Copa Airlines flights
AviancaPriceFrom $323Free CancellationRating
6.6
2,468 reviews
Search Avianca flights
AeromexicoPriceFrom $344Free CancellationRating
7.4
1,672 reviews
Search Aeromexico flights
LATAM AirlinesPriceFrom $513Free CancellationRating
7.5
1,873 reviews
Search LATAM Airlines flights
  • LATAM Airlines Flights From Santiago to Mexico City

    Across 7 LATAM Airlines flights from Santiago to Mexico City this week, the average price was $703, with the best LATAM Airlines deals starting from $513 round-trip. 1,873 users have rated LATAM Airlines on momondo, with an average score of 7.5/10.

  • Aeromexico Flights From Santiago to Mexico City

    Another popular option for Santiago to Mexico City flights is Aeromexico (7.4/10, 1,672 ratings). Aeromexico flies from Santiago to Mexico City around 8 times per week, with deals starting from $344 round-trip and rising to an average price of around $671.

Traveling to a place near Mexico City?

Book flights to Mexico City if you plan to visit one of these locations
Cuernavaca
Tepoztlán
Taxco
Valle de Bravo

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Mexico City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santiago to Mexico City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santiago to Mexico City with flexible booking policies on momondo?

Yes. All flights to Mexico City from Santiago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santiago to Mexico City?

momondo helps you find the best flight between Santiago and Mexico City by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santiago to Mexico City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Mexico City from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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1 adult
Sun 11/30
Sun 12/7

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Airports servicing Mexico City Federal District