Cheap flights from Santiago to Mexico City from $251

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Mexico City departing on 12/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
5:12 am - 12:15 am
SCL
-
MEX
22h 03m1 stop
Copa Airlines Logo
9:25 am - 4:14 am
MEX
-
SCL
15h 49m1 stop
$508Copa Airlines
Tue, Dec 30 - Tue, Jan 6
Multiple Airlines Logo
9:05 pm - 11:10 am
SCL
-
MEX
17h 05m1 stop
Multiple Airlines Logo
9:55 pm - 2:40 pm
MEX
-
SCL
13h 45m1 stop
$527Multiple Airlines
Thu, Jan 29 - Sat, Feb 7
Multiple Airlines Logo
9:05 pm - 11:10 am
SCL
-
MEX
17h 05m1 stop
Multiple Airlines Logo
9:55 pm - 2:40 pm
MEX
-
SCL
13h 45m1 stop
$545Multiple Airlines
Wed, Jan 28 - Wed, Feb 4
LATAM Airlines Logo
3:00 pm - 1:50 pm
SCL
-
MEX
25h 50m1 stop
LATAM Airlines Logo
7:50 pm - 7:30 am
MEX
-
SCL
8h 40mnonstop
$551LATAM Airlines
Tue, Jan 27 - Tue, Feb 3
LATAM Airlines Logo
9:00 am - 2:50 pm
SCL
-
MEX
8h 50mnonstop
LATAM Airlines Logo
7:50 pm - 7:30 am
MEX
-
SCL
8h 40mnonstop
$552LATAM Airlines
Fri, Feb 13 - Tue, Mar 3
Copa Airlines Logo
5:44 am - 12:15 am
SCL
-
MEX
21h 31m1 stop
Copa Airlines Logo
2:00 am - 4:14 am
MEX
-
SCL
23h 14m1 stop
$553Copa Airlines
Wed, Dec 31 - Sun, Jan 4
Multiple Airlines Logo
11:05 pm - 11:10 am
SCL
-
MEX
15h 05m1 stop
Multiple Airlines Logo
9:55 pm - 2:40 pm
MEX
-
SCL
13h 45m1 stop
$555Multiple Airlines
Wed, Feb 11 - Mon, Feb 16
Multiple Airlines Logo
1:35 am - 11:10 am
SCL
-
MEX
36h 35m2 stops
Multiple Airlines Logo
9:55 pm - 10:15 pm
MEX
-
SCL
21h 20m1 stop
$558Multiple Airlines
Tue, Feb 10 - Mon, Feb 16
Multiple Airlines Logo
11:05 pm - 11:10 am
SCL
-
MEX
15h 05m1 stop
Multiple Airlines Logo
9:55 pm - 2:40 pm
MEX
-
SCL
13h 45m1 stop
$561Multiple Airlines
Wed, Feb 11 - Thu, Feb 19
Avianca Logo
4:25 pm - 3:00 am
SCL
-
MEX
13h 35m1 stop
Avianca Logo
5:00 am - 12:30 am
MEX
-
SCL
16h 30m1 stop
$571Avianca
Fri, Feb 13 - Tue, Mar 3

Copa Airlines flights from Santiago to Mexico City

Our best Copa Airlines deals on Santiago to Mexico City flight tickets
Copa Airlines
Dec 30
SCL5:12 amSantiago Arturo Merino Benitez
22h 03m
1 stop
MEX12:15 amMexico City Benito Juarez
Jan 6
MEX9:25 amMexico City Benito Juarez
15h 49m
1 stop
SCL4:14 amSantiago Arturo Merino Benitez
Copa Airlines
Dec 31
SCL5:44 amSantiago Arturo Merino Benitez
21h 31m
1 stop
MEX12:15 amMexico City Benito Juarez
Jan 4
MEX2:00 amMexico City Benito Juarez
23h 14m
1 stop
SCL4:14 amSantiago Arturo Merino Benitez
Copa Airlines
Mar 3
SCL5:21 amSantiago Arturo Merino Benitez
16h 59m
1 stop
MEX7:20 pmMexico City Benito Juarez
Mar 22
MEX5:55 amMexico City Benito Juarez
15h 39m
1 stop
SCL12:34 amSantiago Arturo Merino Benitez

LATAM Airlines flights from Santiago to Mexico City

Our best LATAM Airlines deals on Santiago to Mexico City flight tickets
LATAM Airlines
Jan 27
SCL3:00 pmSantiago Arturo Merino Benitez
25h 50m
1 stop
MEX1:50 pmMexico City Benito Juarez
Feb 3
MEX7:50 pmMexico City Benito Juarez
8h 40m
SCL7:30 amSantiago Arturo Merino Benitez
LATAM Airlines
Feb 13
SCL9:00 amSantiago Arturo Merino Benitez
8h 50m
MEX2:50 pmMexico City Benito Juarez
Mar 3
MEX7:50 pmMexico City Benito Juarez
8h 40m
SCL7:30 amSantiago Arturo Merino Benitez
LATAM Airlines
Jan 29
SCL6:30 pmSantiago Arturo Merino Benitez
22h 20m
1 stop
MEX1:50 pmMexico City Benito Juarez
Feb 6
MEX7:50 pmMexico City Benito Juarez
8h 40m
SCL7:30 amSantiago Arturo Merino Benitez

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Santiago to Mexico City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Tue 12/30

5:12 am-12:15 am

1 stop22h 03m

Mexico City Benito Juarez

Tue 1/6

9:25 am-4:14 am

1 stop15h 49m

$508

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Thu 1/29

9:05 pm-11:10 am

1 stop17h 05m

Mexico City Benito Juarez

Sat 2/7

9:55 pm-2:40 pm

1 stop13h 45m

$527

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Wed 1/28

9:05 pm-11:10 am

1 stop17h 05m

Mexico City Benito Juarez

Wed 2/4

9:55 pm-2:40 pm

1 stop13h 45m

$545

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Tue 1/27

3:00 pm-1:50 pm

1 stop25h 50m

Mexico City Benito Juarez

Tue 2/3

7:50 pm-7:30 am

Nonstop8h 40m

$551

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Fri 2/13

9:00 am-2:50 pm

Nonstop8h 50m

Mexico City Benito Juarez

Tue 3/3

7:50 pm-7:30 am

Nonstop8h 40m

$552

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Wed 12/31

5:44 am-12:15 am

1 stop21h 31m

Mexico City Benito Juarez

Sun 1/4

2:00 am-4:14 am

1 stop23h 14m

$553

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Wed 2/11

11:05 pm-11:10 am

1 stop15h 05m

Mexico City Benito Juarez

Mon 2/16

9:55 pm-2:40 pm

1 stop13h 45m

$555

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Tue 2/10

1:35 am-11:10 am

2 stops36h 35m

Mexico City Benito Juarez

Mon 2/16

9:55 pm-10:15 pm

1 stop21h 20m

$558

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Wed 2/11

11:05 pm-11:10 am

1 stop15h 05m

Mexico City Benito Juarez

Thu 2/19

9:55 pm-2:40 pm

1 stop13h 45m

$561

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Fri 2/13

4:25 pm-3:00 am

1 stop13h 35m

Mexico City Benito Juarez

Tue 3/3

5:00 am-12:30 am

1 stop16h 30m

$571

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Mexico City from

How to get the cheapest flight ticket from Santiago to Mexico City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and Mexico City?

What is the cheapest month to fly to Mexico City?

The cheapest month to fly to Mexico City from Santiago is in March. Flight prices, which tend to average around $546, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of March, then book flights to Mexico City from Santiago during November instead. Flights to Mexico City in November, while not as cheap as those in March, still average around $570.

What is the cheapest day to depart on your flight to Mexico City?

Our data shows that Tuesday is the least expensive day to fly to Mexico City. Tickets to fly out on this day can be as low as $655. On the other hand, Friday is the most expensive day to depart from Santiago because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $902.

What is the cheapest time of day to depart on your flight to Mexico City?

According to our data, the cheapest time of day to fly to Mexico City is at noon. momondo users have found flights departing from Santiago to Mexico City at noon for as low as $496. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the morning is when there is more demand to fly to Mexico City, so prices are often more expensive at around $796 per ticket.

What is the cheapest Santiago Arturo Merino Benitez to Mexico City Benito Juarez flight route?

Fly from Santiago Arturo Merino Benitez to Mexico City Benito Juarez for the best Santiago Arturo Merino Benitez - Mexico City Benito Juarez flight prices

How far in advance should I book a flight to Mexico City?

You are more likely to see cheaper flights to Mexico City from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Mexico City for around $600 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Mexico City from Santiago for as low as $527 on momondo.

What cabin class options are available on Santiago Arturo Merino Benitez to Mexico City Benito Juarez flights?

There are 3 cabin classes available to choose from on Santiago Arturo Merino Benitez to Mexico City Benito Juarez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santiago to Mexico City flights?

No. A direct flight is the cheapest option for a flight between Santiago to Mexico City.

How have Santiago to Mexico City flight prices changed over time?

As of December 2025, prices for Santiago to Mexico City flights are approximately 9% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to Mexico City

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Mexico City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Mexico City (SCL to MEX) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Mexico City

Best Price Found

$347

Fastest flight time

8h 30m

Direct flights

Every day

Airports in Mexico City

1 airport
The best one-way flight to Mexico City from Santiago in the past 72 hours is $347. The best round-trip flight deal from Santiago to Mexico City found on momondo in the last 72 hours is $555.
The fastest flight from Santiago to Mexico City takes 8h 30m
Direct flights go from Santiago to Mexico City every day.
There is 1 airport in Mexico City. From Santiago there are direct flights to Mexico City Benito Juarez (MEX).
  • How far is Santiago Arturo Merino Benitez to Mexico City Benito Juarez by plane?

    There are 4104.7 mi between Santiago Arturo Merino Benitez and Mexico City Benito Juarez. By plane, this route typically takes 8h 30m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Mexico City Benito Juarez Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Mexico City Benito Juarez Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Mexico City Benito Juarez Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Mexico City Benito Juarez Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Mexico City Benito Juarez Airport.

  • What documentation or ID do you need to fly to Mexico City Benito Juarez Airport?

    The travel and health documents you'll need for your trip to Mexico City Benito Juarez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Mexico City Benito Juarez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santiago to Mexico City?

  • What is the most popular airline from Santiago to Mexico City?

Best airlines flying from Santiago to Mexico City

Compare and see reviews for airlines that fly from Santiago to Mexico City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $477Free CancellationRating
7.6
1,556 reviews
Search Copa Airlines flights
AviancaPriceFrom $487Free CancellationRating
6.6
2,485 reviews
Search Avianca flights
LATAM AirlinesPriceFrom $508Free CancellationRating
7.5
1,891 reviews
Search LATAM Airlines flights
AeromexicoPriceFrom $525Free CancellationRating
7.4
1,631 reviews
Search Aeromexico flights
  • LATAM Airlines Flights From Santiago to Mexico City

    Across 7 LATAM Airlines flights from Santiago to Mexico City this week, the average price was $694, with the best LATAM Airlines deals starting from $508 round-trip. 1,891 users have rated LATAM Airlines on momondo, with an average score of 7.5/10.

  • Aeromexico Flights From Santiago to Mexico City

    Another popular option for Santiago to Mexico City flights is Aeromexico (7.4/10, 1,631 ratings). Aeromexico flies from Santiago to Mexico City around 6 times per week, with deals starting from $525 round-trip and rising to an average price of around $603.

Traveling to a place near Mexico City?

Book flights to Mexico City if you plan to visit one of these locations
Cuernavaca
Tepoztlán
Taxco
Valle de Bravo

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Mexico City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santiago to Mexico City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santiago to Mexico City with flexible booking policies on momondo?

Yes. All flights to Mexico City from Santiago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santiago to Mexico City?

momondo helps you find the best flight between Santiago and Mexico City by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santiago to Mexico City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Mexico City from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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1 adult
Wed 1/14
Wed 1/21

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Airports servicing Mexico City Federal District