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Cheap flights from Santiago to Medellín from $134

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Medellín departing on 8/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

LATAM Airlines Logo
4:55 pm - 2:50 amSCL-MDE
10h 55m1 stop
LATAM Airlines Logo
10:18 pm - 2:30 pmMDE-SCL
14h 12m1 stop
$288LATAM Airlines
Find Deal
Thu, Sep 4 - Tue, Sep 9
LATAM Airlines Logo
5:35 am - 3:45 pmSCL-MDE
11h 10m1 stop
LATAM Airlines Logo
3:55 am - 5:25 pmMDE-SCL
11h 30m1 stop
$289LATAM Airlines
Find Deal
Sun, Aug 17 - Thu, Sep 11
Copa Airlines Logo
12:24 am - 8:17 amSCL-MDE
8h 53m1 stop
Copa Airlines Logo
12:45 pm - 11:40 pmMDE-SCL
8h 55m1 stop
$292Copa Airlines
Find Deal
Wed, Sep 3 - Tue, Sep 9
LATAM Airlines Logo
11:25 pm - 8:27 amSCL-MDE
10h 02m1 stop
LATAM Airlines Logo
10:02 pm - 1:30 pmMDE-SCL
14h 28m1 stop
$294LATAM Airlines
Find Deal
Wed, Aug 27 - Wed, Sep 3
LATAM Airlines Logo
4:55 pm - 2:50 amSCL-MDE
10h 55m1 stop
LATAM Airlines Logo
9:01 am - 9:55 pmMDE-SCL
10h 54m2 stops
$295LATAM Airlines
Find Deal
Thu, Sep 4 - Tue, Sep 9
Copa Airlines Logo
2:26 am - 2:45 pmSCL-MDE
13h 19m1 stop
Copa Airlines Logo
9:15 am - 10:44 pmMDE-SCL
12h 29m1 stop
$322Copa Airlines
Find Deal
Tue, Aug 12 - Wed, Aug 27
JetSMART Logo
3:37 pm - 2:08 pmSCL-MDE
24h 31m1 stop
JetSMART Logo
1:13 pm - 9:21 pmMDE-SCL
6h 08mnonstop
$365JetSMART
Find Deal
Thu, Dec 25 - Mon, Jan 5
JetSMART Logo
5:59 am - 4:49 pmSCL-MDE
12h 50m1 stop
JetSMART Logo
1:13 pm - 9:21 pmMDE-SCL
6h 08mnonstop
$374JetSMART
Find Deal
Thu, Dec 25 - Mon, Jan 5
Logo
12:24 am - 8:17 amSCL-MDE
8h 53m1 stop
Logo
11:54 am - 4:17 amMDE-SCL
15h 23m2 stops
$388
Find Deal
Tue, Sep 2 - Wed, Sep 3
Logo
12:40 am - 5:20 pmSCL-MDE
17h 40m2 stops
Logo
6:09 pm - 5:01 amMDE-SCL
8h 52m1 stop
$396
Find Deal
Wed, Sep 3 - Thu, Sep 11

LATAM Airlines flights from Santiago to Medellín Jose Maria Cordova Intl Airport

Our best LATAM Airlines deals on Santiago to Medellín Jose Maria Cordova Intl Airport flight tickets
LATAM Airlines
Sep 4
SCL4:55 pmSantiago Arturo Merino Benitez
10h 55m
1 stop
MDE2:50 amMedellín Jose Maria Cordova Intl
Sep 9
MDE10:18 pmMedellín Jose Maria Cordova Intl
14h 12m
1 stop
SCL2:30 pmSantiago Arturo Merino Benitez
$288
Find similar
LATAM Airlines
Aug 17
SCL5:35 amSantiago Arturo Merino Benitez
11h 10m
1 stop
MDE3:45 pmMedellín Jose Maria Cordova Intl
Sep 11
MDE3:55 amMedellín Jose Maria Cordova Intl
11h 30m
1 stop
SCL5:25 pmSantiago Arturo Merino Benitez
$289
Find similar
LATAM Airlines
Aug 27
SCL11:25 pmSantiago Arturo Merino Benitez
10h 02m
1 stop
MDE8:27 amMedellín Jose Maria Cordova Intl
Sep 3
MDE10:02 pmMedellín Jose Maria Cordova Intl
14h 28m
1 stop
SCL1:30 pmSantiago Arturo Merino Benitez
$294
Find similar

Copa Airlines flights from Santiago to Medellín Jose Maria Cordova Intl Airport

Our best Copa Airlines deals on Santiago to Medellín Jose Maria Cordova Intl Airport flight tickets
Copa Airlines
Sep 3
SCL12:24 amSantiago Arturo Merino Benitez
8h 53m
1 stop
MDE8:17 amMedellín Jose Maria Cordova Intl
Sep 9
MDE12:45 pmMedellín Jose Maria Cordova Intl
8h 55m
1 stop
SCL11:40 pmSantiago Arturo Merino Benitez
$292
Find similar
Copa Airlines
Aug 12
SCL2:26 amSantiago Arturo Merino Benitez
13h 19m
1 stop
MDE2:45 pmMedellín Jose Maria Cordova Intl
Aug 27
MDE9:15 amMedellín Jose Maria Cordova Intl
12h 29m
1 stop
SCL10:44 pmSantiago Arturo Merino Benitez
$322
Find similar
Copa Airlines
Sep 7
SCL1:24 amSantiago Arturo Merino Benitez
11h 31m
1 stop
MDE10:55 amMedellín Jose Maria Cordova Intl
Sep 16
MDE10:46 amMedellín Jose Maria Cordova Intl
11h 18m
1 stop
SCL12:04 amSantiago Arturo Merino Benitez
$337
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Medellín Jose Maria Cordova Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Santiago to Medellín Jose Maria Cordova Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Thu 9/4

4:55 pm-2:50 am

1 stop10h 55m

Medellín Jose Maria Cordova Intl

Tue 9/9

10:18 pm-2:30 pm

1 stop14h 12m

$288

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Sun 8/17

5:35 am-3:45 pm

1 stop11h 10m

Medellín Jose Maria Cordova Intl

Thu 9/11

3:55 am-5:25 pm

1 stop11h 30m

$289

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Wed 9/3

12:24 am-8:17 am

1 stop8h 53m

Medellín Jose Maria Cordova Intl

Tue 9/9

12:45 pm-11:40 pm

1 stop8h 55m

$292

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Wed 8/27

11:25 pm-8:27 am

1 stop10h 02m

Medellín Jose Maria Cordova Intl

Wed 9/3

10:02 pm-1:30 pm

1 stop14h 28m

$294

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Thu 9/4

4:55 pm-2:50 am

1 stop10h 55m

Medellín Jose Maria Cordova Intl

Tue 9/9

9:01 am-9:55 pm

2 stops10h 54m

$295

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Tue 8/12

2:26 am-2:45 pm

1 stop13h 19m

Medellín Jose Maria Cordova Intl

Wed 8/27

9:15 am-10:44 pm

1 stop12h 29m

$322

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Thu 12/25

3:37 pm-2:08 pm

1 stop24h 31m

Medellín Jose Maria Cordova Intl

Mon 1/5

1:13 pm-9:21 pm

Nonstop6h 08m

$365

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Thu 12/25

5:59 am-4:49 pm

1 stop12h 50m

Medellín Jose Maria Cordova Intl

Mon 1/5

1:13 pm-9:21 pm

Nonstop6h 08m

$374

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Tue 9/2

12:24 am-8:17 am

1 stop8h 53m

Medellín Jose Maria Cordova Intl

Wed 9/3

11:54 am-4:17 am

2 stops15h 23m

$388

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Wed 9/3

12:40 am-5:20 pm

2 stops17h 40m

Medellín Jose Maria Cordova Intl

Thu 9/11

6:09 pm-5:01 am

1 stop8h 52m

$396

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Medellín from

How to get the cheapest flight ticket from Santiago to Medellín Jose Maria Cordova Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Medellín Jose Maria Cordova Intl Airport?

In general, October is the cheapest month to fly from Santiago to Medellín Jose Maria Cordova Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $301. If you aren’t able to travel during the month of October, then book flights to Medellín Jose Maria Cordova Intl Airport from Santiago during November instead. Flights to Medellín Jose Maria Cordova Intl Airport in November, while not as cheap as those in October, still average around $301.

What is the cheapest day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

The cheapest day to depart from Santiago to Medellín Jose Maria Cordova Intl Airport is on a Sunday. Travelers who choose to depart for Medellín Jose Maria Cordova Intl Airport on a Sunday will often find tickets for as low as $309. On the other hand, Saturday is the most expensive day to depart from Santiago because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $540.

What is the cheapest time of day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

Our data shows that the cheapest Santiago to Medellín Jose Maria Cordova Intl Airport flights are usually those with departure times in the morning. Our users have found flights to Medellín Jose Maria Cordova Intl Airport in the morning for as low as $399. In contrast, the most expensive time of day to depart to Medellín Jose Maria Cordova Intl Airport is in the evening when prices are around $498.

What is the cheapest Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl flight route?

Fly from Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl for the best Santiago Arturo Merino Benitez - Medellín Jose Maria Cordova Intl flight prices

How far in advance should I book a flight to Medellín Jose Maria Cordova Intl Airport?

You are more likely to see cheaper flights to Medellín Jose Maria Cordova Intl Airport from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Medellín Jose Maria Cordova Intl Airport for around $352 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Medellín Jose Maria Cordova Intl Airport from Santiago for as low as $323 on momondo.

What cabin class options are available on Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl flights?

There are 2 cabin classes available to choose from on Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Santiago to Medellín Jose Maria Cordova Intl Airport flight prices changed over time?

As of July 2025, prices for Santiago to Medellín Jose Maria Cordova Intl Airport flights are approximately 26% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to Medellín Jose Maria Cordova Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Medellín Jose Maria Cordova Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Medellín Jose Maria Cordova Intl Airport (SCL to MDE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Medellín Jose Maria Cordova Intl Airport

Best Price Found

$134

Fastest flight time

8h 53m

Direct flights

None
The best one-way flight to Medellín Jose Maria Cordova Intl Airport from Santiago in the past 72 hours is $134. The best round-trip flight deal from Santiago to Medellín Jose Maria Cordova Intl Airport found on momondo in the last 72 hours is $288.
The fastest flight from Santiago to Medellín Jose Maria Cordova Intl Airport takes 8h 53m
There are no direct flights from Santiago to Medellín Jose Maria Cordova Intl Airport. Popular non-direct route for this connection is Santiago Arturo Merino Benitez Airport - Medellín Jose Maria Cordova Intl Airport.
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  • How far is Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl by plane?

    There are 2752.8 mi between Santiago Arturo Merino Benitez and Medellín Jose Maria Cordova Intl. 8h 53m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport.

  • What documentation or ID do you need to fly to Medellín Jose Maria Cordova Intl Airport?

    The travel and health documents you'll need for your trip to Medellín Jose Maria Cordova Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Medellín Jose Maria Cordova Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santiago to Medellín Jose Maria Cordova Intl Airport?

  • What is the most popular airline from Santiago to Medellín Jose Maria Cordova Intl Airport?

Best airlines flying from Santiago to Medellín Jose Maria Cordova Intl Airport

Compare and see reviews for airlines that fly from Santiago to Medellín Jose Maria Cordova Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $249Free CancellationRating
7.5
1,822 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $250Free CancellationRating
7.5
1,493 reviews
Search Copa Airlines flights
AviancaPriceFrom $296Free CancellationRating
6.7
2,388 reviews
Search Avianca flights
JetSMARTPriceFrom $299Free CancellationRating
6.5
211 reviews
Search JetSMART flights

Traveling to a place near Medellín?

Book flights to Medellín if you plan to visit one of these locations
Guatapé
Rionegro

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Can I find flights from Santiago to Medellín with flexible booking policies on momondo?

All flight searches from Santiago to Medellín on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to Medellín?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Medellín from Santiago.

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