Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Santiago to Medellín from $155

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Medellín departing on 2/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Santiago to Medellín

Cheap round-trip flights

JetSMART Logo
7:49 am - 12:13 pmSCL-MDE
6h 24mnonstop
JetSMART Logo
1:13 pm - 9:21 pmMDE-SCL
6h 08mnonstop
$295JetSMART
Find Deal
Sun, Mar 8 - Sun, Mar 15
JetSMART Logo
7:49 am - 12:13 pmSCL-MDE
6h 24mnonstop
JetSMART Logo
6:09 pm - 8:31 pmMDE-SCL
24h 22m1 stop
$296JetSMART
Find Deal
Sun, Mar 8 - Tue, Mar 10
Copa Airlines Logo
12:20 pm - 8:00 pmSCL-MDE
9h 40m1 stop
Copa Airlines Logo
5:00 am - 8:21 pmMDE-SCL
13h 21m1 stop
$352Copa Airlines
Find Deal
Thu, Nov 20 - Thu, Nov 27
LATAM Airlines Logo
8:20 am - 4:15 pmSCL-MDE
9h 55m1 stop
LATAM Airlines Logo
4:05 pm - 5:50 amMDE-SCL
11h 45m2 stops
$355LATAM Airlines
Find Deal
Tue, Mar 10 - Tue, Mar 24
Avianca Logo
4:25 pm - 11:15 pmSCL-MDE
8h 50m1 stop
Avianca Logo
2:05 pm - 12:30 amMDE-SCL
8h 25m1 stop
$361Avianca
Find Deal
Tue, Oct 28 - Tue, Nov 4
Copa Airlines Logo
1:13 am - 2:15 pmSCL-MDE
15h 02m1 stop
Copa Airlines Logo
9:15 am - 8:20 pmMDE-SCL
9h 05m1 stop
$365Copa Airlines
Find Deal
Tue, Sep 30 - Wed, Oct 15
Avianca Logo
1:35 am - 10:00 amSCL-MDE
10h 25m1 stop
Avianca Logo
4:20 am - 3:20 pmMDE-SCL
9h 00m1 stop
$369Avianca
Find Deal
Wed, Nov 19 - Wed, Nov 26
LATAM Airlines Logo
12:20 am - 7:45 amSCL-MDE
9h 25m1 stop
LATAM Airlines Logo
6:10 pm - 6:35 amMDE-SCL
10h 25m1 stop
$374LATAM Airlines
Find Deal
Mon, Oct 27 - Tue, Nov 4
Logo
1:35 am - 10:55 amSCL-MDE
11h 20m1 stop
Logo
9:15 pm - 5:25 pmMDE-SCL
18h 10m2 stops
$427
Find Deal
Wed, Nov 19 - Thu, Nov 27
Logo
12:20 am - 8:55 amSCL-MDE
10h 35m1 stop
Logo
4:20 am - 3:20 pmMDE-SCL
9h 00m1 stop
$432
Find Deal
Wed, Oct 29 - Wed, Nov 5

JetSMART flights from Santiago to Medellín Jose Maria Cordova Intl Airport

Our best JetSMART deals on Santiago to Medellín Jose Maria Cordova Intl Airport flight tickets
JetSMART
Mar 8
SCL7:49 amSantiago Arturo Merino Benitez
6h 24m
MDE12:13 pmMedellín Jose Maria Cordova Intl
Mar 15
MDE1:13 pmMedellín Jose Maria Cordova Intl
6h 08m
SCL9:21 pmSantiago Arturo Merino Benitez
$295
Find similar
JetSMART
Mar 8
SCL7:49 amSantiago Arturo Merino Benitez
6h 24m
MDE12:13 pmMedellín Jose Maria Cordova Intl
Mar 10
MDE6:09 pmMedellín Jose Maria Cordova Intl
24h 22m
1 stop
SCL8:31 pmSantiago Arturo Merino Benitez
$296
Find similar
JetSMART
Mar 8
SCL9:36 pmSantiago Arturo Merino Benitez
21h 29m
1 stop
MDE5:05 pmMedellín Jose Maria Cordova Intl
Mar 15
MDE1:13 pmMedellín Jose Maria Cordova Intl
6h 08m
SCL9:21 pmSantiago Arturo Merino Benitez
$302
Find similar

Copa Airlines flights from Santiago to Medellín Jose Maria Cordova Intl Airport

Our best Copa Airlines deals on Santiago to Medellín Jose Maria Cordova Intl Airport flight tickets
Copa Airlines
Nov 20
SCL12:20 pmSantiago Arturo Merino Benitez
9h 40m
1 stop
MDE8:00 pmMedellín Jose Maria Cordova Intl
Nov 27
MDE5:00 amMedellín Jose Maria Cordova Intl
13h 21m
1 stop
SCL8:21 pmSantiago Arturo Merino Benitez
$352
Find similar
Copa Airlines
Sep 30
SCL1:13 amSantiago Arturo Merino Benitez
15h 02m
1 stop
MDE2:15 pmMedellín Jose Maria Cordova Intl
Oct 15
MDE9:15 amMedellín Jose Maria Cordova Intl
9h 05m
1 stop
SCL8:20 pmSantiago Arturo Merino Benitez
$365
Find similar
Copa Airlines
Sep 16
SCL5:22 amSantiago Arturo Merino Benitez
11h 22m
1 stop
MDE2:44 pmMedellín Jose Maria Cordova Intl
May 15
MDE5:00 amMedellín Jose Maria Cordova Intl
17h 32m
1 stop
SCL11:32 pmSantiago Arturo Merino Benitez
$367
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Medellín Jose Maria Cordova Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Santiago to Medellín Jose Maria Cordova Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Sun 3/8

7:49 am-12:13 pm

Nonstop6h 24m

Medellín Jose Maria Cordova Intl

Sun 3/15

1:13 pm-9:21 pm

Nonstop6h 08m

$295

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Sun 3/8

7:49 am-12:13 pm

Nonstop6h 24m

Medellín Jose Maria Cordova Intl

Tue 3/10

6:09 pm-8:31 pm

1 stop24h 22m

$296

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Thu 11/20

12:20 pm-8:00 pm

1 stop9h 40m

Medellín Jose Maria Cordova Intl

Thu 11/27

5:00 am-8:21 pm

1 stop13h 21m

$352

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Tue 3/10

8:20 am-4:15 pm

1 stop9h 55m

Medellín Jose Maria Cordova Intl

Tue 3/24

4:05 pm-5:50 am

2 stops11h 45m

$355

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Tue 10/28

4:25 pm-11:15 pm

1 stop8h 50m

Medellín Jose Maria Cordova Intl

Tue 11/4

2:05 pm-12:30 am

1 stop8h 25m

$361

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Tue 9/30

1:13 am-2:15 pm

1 stop15h 02m

Medellín Jose Maria Cordova Intl

Wed 10/15

9:15 am-8:20 pm

1 stop9h 05m

$365

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Wed 11/19

1:35 am-10:00 am

1 stop10h 25m

Medellín Jose Maria Cordova Intl

Wed 11/26

4:20 am-3:20 pm

1 stop9h 00m

$369

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Mon 10/27

12:20 am-7:45 am

1 stop9h 25m

Medellín Jose Maria Cordova Intl

Tue 11/4

6:10 pm-6:35 am

1 stop10h 25m

$374

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Wed 11/19

1:35 am-10:55 am

1 stop11h 20m

Medellín Jose Maria Cordova Intl

Thu 11/27

9:15 pm-5:25 pm

2 stops18h 10m

$427

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Wed 10/29

12:20 am-8:55 am

1 stop10h 35m

Medellín Jose Maria Cordova Intl

Wed 11/5

4:20 am-3:20 pm

1 stop9h 00m

$432

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Medellín from

How to get the cheapest flight ticket from Santiago to Medellín Jose Maria Cordova Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Medellín Jose Maria Cordova Intl Airport?

In general, November is the cheapest month to fly from Santiago to Medellín Jose Maria Cordova Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $312. If you aren’t able to travel during the month of November, then book flights to Medellín Jose Maria Cordova Intl Airport from Santiago during March instead. Flights to Medellín Jose Maria Cordova Intl Airport in March, while not as cheap as those in November, still average around $327.

What is the cheapest day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

The cheapest day to depart from Santiago to Medellín Jose Maria Cordova Intl Airport is on a Sunday. Travelers who choose to depart for Medellín Jose Maria Cordova Intl Airport on a Sunday will often find tickets for as low as $309. On the other hand, Monday is the most expensive day to depart from Santiago because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $518.

What is the cheapest time of day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

Our data shows that the cheapest Santiago to Medellín Jose Maria Cordova Intl Airport flights are usually those with departure times in the morning. Our users have found flights to Medellín Jose Maria Cordova Intl Airport in the morning for as low as $399. In contrast, the most expensive time of day to depart to Medellín Jose Maria Cordova Intl Airport is in the evening when prices are around $512.

What is the cheapest Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl flight route?

Fly from Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl for the best Santiago Arturo Merino Benitez - Medellín Jose Maria Cordova Intl flight prices

How far in advance should I book a flight to Medellín Jose Maria Cordova Intl Airport?

You are more likely to see cheaper flights to Medellín Jose Maria Cordova Intl Airport from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Medellín Jose Maria Cordova Intl Airport for around $360 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Medellín Jose Maria Cordova Intl Airport from Santiago for as low as $315 on momondo.

What cabin class options are available on Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl flights?

There are 2 cabin classes available to choose from on Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Santiago to Medellín Jose Maria Cordova Intl Airport flight prices changed over time?

As of September 2025, prices for Santiago to Medellín Jose Maria Cordova Intl Airport flights are approximately 22% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to Medellín Jose Maria Cordova Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Medellín Jose Maria Cordova Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Medellín Jose Maria Cordova Intl Airport (SCL to MDE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Medellín Jose Maria Cordova Intl Airport

Best Price Found

$344

Fastest flight time

6h 15m

Direct flights

Mon, Tue, Wed, Thu, Fri and Sat
The best flight deal from Santiago to Medellín Jose Maria Cordova Intl Airport found on momondo in the last 72 hours is $344
The fastest flight from Santiago to Medellín Jose Maria Cordova Intl Airport takes 6h 15m
Direct flights go from Santiago to Medellín Jose Maria Cordova Intl Airport on Monday, Tuesday, Wednesday, Thursday, Friday and Saturday. There are no airlines offering direct flights.
Search flight deals

  • How far is Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl by plane?

    There are 2752.8 mi between Santiago Arturo Merino Benitez and Medellín Jose Maria Cordova Intl. 6h 15m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport.

  • What documentation or ID do you need to fly to Medellín Jose Maria Cordova Intl Airport?

    The travel and health documents you'll need for your trip to Medellín Jose Maria Cordova Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Medellín Jose Maria Cordova Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santiago to Medellín Jose Maria Cordova Intl Airport?

  • What is the most popular airline from Santiago to Medellín Jose Maria Cordova Intl Airport?

Best airlines flying from Santiago to Medellín Jose Maria Cordova Intl Airport

Compare and see reviews for airlines that fly from Santiago to Medellín Jose Maria Cordova Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $249Free CancellationRating
7.5
1,847 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $292Free CancellationRating
7.6
1,531 reviews
Search Copa Airlines flights
AviancaPriceFrom $296Free CancellationRating
6.7
2,435 reviews
Search Avianca flights
JetSMARTPriceFrom $313Free CancellationRating
6.5
225 reviews
Search JetSMART flights

Traveling to a place near Medellín?

Book flights to Medellín if you plan to visit one of these locations
Guatapé
Rionegro

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Medellín?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to Medellín. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to Medellín with flexible booking policies on momondo?

All flight searches from Santiago to Medellín on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to Medellín?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Medellín from Santiago.

I’m not ready to book a flight from Santiago to Medellín right now. Can momondo alert me if prices change?

Price alerts on flights to Medellín from Santiago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Medellín Jose Maria Cordova Intl Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 10/15
Wed 10/22
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Medellín

Popular cities in Colombia

Popular flights according to clicks in the last 7 days on momondo
Flights to Medellín Enrique Olaya Airportfrom $346