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Cheap flights from Santiago to Medellín from $177

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Medellín departing on 3/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Enter your travel dates to find the best prices.
JetSMART Logo
12:59 am - 6:23 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
6:05 am - 4:17 am
MDE
-
SCL
21h 12m1 stop
$339JetSMART
Fri, May 1 - Fri, May 15
JetSMART Logo
12:59 am - 6:23 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
5:30 am - 5:24 pm
MDE
-
SCL
34h 54m2 stops
$340JetSMART
Sun, May 31 - Sat, Jun 13
JetSMART Logo
3:37 pm - 10:48 pm
SCL
-
MDE
9h 11m1 stop
JetSMART Logo
5:35 pm - 5:14 am
MDE
-
SCL
9h 39m1 stop
$342JetSMART
Wed, Mar 25 - Tue, Mar 31
JetSMART Logo
3:33 pm - 11:00 pm
SCL
-
MDE
8h 27m1 stop
JetSMART Logo
5:01 pm - 12:09 am
MDE
-
SCL
6h 08mnonstop
$343JetSMART
Fri, May 1 - Fri, May 15
JetSMART Logo
12:59 am - 6:23 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
5:01 pm - 12:09 am
MDE
-
SCL
6h 08mnonstop
$344JetSMART
Mon, Apr 13 - Sun, Apr 19
JetSMART Logo
12:59 am - 6:23 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
5:30 am - 5:24 pm
MDE
-
SCL
34h 54m2 stops
$345JetSMART
Thu, May 14 - Sat, May 30
JetSMART Logo
3:37 pm - 11:01 pm
SCL
-
MDE
9h 24m1 stop
JetSMART Logo
5:01 pm - 1:09 am
MDE
-
SCL
6h 08mnonstop
$346JetSMART
Fri, Mar 6 - Mon, Mar 16
JetSMART Logo
12:59 am - 6:23 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
6:05 am - 4:17 am
MDE
-
SCL
21h 12m1 stop
$347JetSMART
Fri, Apr 10 - Fri, Apr 24
JetSMART Logo
12:59 am - 6:23 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
3:13 pm - 5:24 pm
MDE
-
SCL
49h 11m2 stops
$348JetSMART
Thu, Apr 9 - Fri, Apr 24
LATAM Airlines Logo
5:15 am - 4:15 pm
SCL
-
MDE
13h 00m1 stop
LATAM Airlines Logo
4:00 am - 4:30 pm
MDE
-
SCL
11h 30m1 stop
$349LATAM Airlines
Thu, Mar 26 - Sat, Apr 11

Copa Airlines flights from Santiago to Medellín Jose Maria Cordova Intl Airport

Our best Copa Airlines deals on Santiago to Medellín Jose Maria Cordova Intl Airport flight tickets
Copa Airlines
Mar 14
SCL5:21 amSantiago Arturo Merino Benitez
10h 54m
1 stop
MDE2:15 pmMedellín Jose Maria Cordova Intl
Mar 21
MDE8:37 amMedellín Jose Maria Cordova Intl
13h 57m
1 stop
SCL12:34 amSantiago Arturo Merino Benitez
$378
Find similar
Copa Airlines
Jan 2
SCL5:20 amSantiago Arturo Merino Benitez
11h 25m
1 stop
MDE2:45 pmMedellín Jose Maria Cordova Intl
Jan 9
MDE4:30 pmMedellín Jose Maria Cordova Intl
9h 44m
1 stop
SCL4:14 amSantiago Arturo Merino Benitez
$393
Find similar
Copa Airlines
Dec 26
SCL5:12 amSantiago Arturo Merino Benitez
11h 03m
1 stop
MDE2:15 pmMedellín Jose Maria Cordova Intl
Jan 1
MDE8:37 amMedellín Jose Maria Cordova Intl
9h 43m
1 stop
SCL8:20 pmSantiago Arturo Merino Benitez
$398
Find similar

JetSMART flights from Santiago to Medellín Jose Maria Cordova Intl Airport

Our best JetSMART deals on Santiago to Medellín Jose Maria Cordova Intl Airport flight tickets
JetSMART
May 1
SCL12:59 amSantiago Arturo Merino Benitez
6h 24m
MDE6:23 amMedellín Jose Maria Cordova Intl
May 15
MDE6:05 amMedellín Jose Maria Cordova Intl
21h 12m
1 stop
SCL4:17 amSantiago Arturo Merino Benitez
$339
Find similar
JetSMART
May 31
SCL12:59 amSantiago Arturo Merino Benitez
6h 24m
MDE6:23 amMedellín Jose Maria Cordova Intl
Jun 13
MDE5:30 amMedellín Jose Maria Cordova Intl
34h 54m
2 stops
SCL5:24 pmSantiago Arturo Merino Benitez
$340
Find similar
JetSMART
Mar 25
SCL3:37 pmSantiago Arturo Merino Benitez
9h 11m
1 stop
MDE10:48 pmMedellín Jose Maria Cordova Intl
Mar 31
MDE5:35 pmMedellín Jose Maria Cordova Intl
9h 39m
1 stop
SCL5:14 amSantiago Arturo Merino Benitez
$342
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Medellín Jose Maria Cordova Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Santiago to Medellín Jose Maria Cordova Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Fri 5/1

12:59 am-6:23 am

Nonstop6h 24m

Medellín Jose Maria Cordova Intl

Fri 5/15

6:05 am-4:17 am

1 stop21h 12m

$339

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Sun 5/31

12:59 am-6:23 am

Nonstop6h 24m

Medellín Jose Maria Cordova Intl

Sat 6/13

5:30 am-5:24 pm

2 stops34h 54m

$340

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Wed 3/25

3:37 pm-10:48 pm

1 stop9h 11m

Medellín Jose Maria Cordova Intl

Tue 3/31

5:35 pm-5:14 am

1 stop9h 39m

$342

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Fri 5/1

3:33 pm-11:00 pm

1 stop8h 27m

Medellín Jose Maria Cordova Intl

Fri 5/15

5:01 pm-12:09 am

Nonstop6h 08m

$343

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Mon 4/13

12:59 am-6:23 am

Nonstop6h 24m

Medellín Jose Maria Cordova Intl

Sun 4/19

5:01 pm-12:09 am

Nonstop6h 08m

$344

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Thu 5/14

12:59 am-6:23 am

Nonstop6h 24m

Medellín Jose Maria Cordova Intl

Sat 5/30

5:30 am-5:24 pm

2 stops34h 54m

$345

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Fri 3/6

3:37 pm-11:01 pm

1 stop9h 24m

Medellín Jose Maria Cordova Intl

Mon 3/16

5:01 pm-1:09 am

Nonstop6h 08m

$346

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Fri 4/10

12:59 am-6:23 am

Nonstop6h 24m

Medellín Jose Maria Cordova Intl

Fri 4/24

6:05 am-4:17 am

1 stop21h 12m

$347

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Thu 4/9

12:59 am-6:23 am

Nonstop6h 24m

Medellín Jose Maria Cordova Intl

Fri 4/24

3:13 pm-5:24 pm

2 stops49h 11m

$348

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

Thu 3/26

5:15 am-4:15 pm

1 stop13h 00m

Medellín Jose Maria Cordova Intl

Sat 4/11

4:00 am-4:30 pm

1 stop11h 30m

$349

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Santiago to Medellín Jose Maria Cordova Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and Medellín Jose Maria Cordova Intl Airport?

What is the cheapest month to fly to Medellín Jose Maria Cordova Intl Airport?

In general, March is the cheapest month to fly from Santiago to Medellín Jose Maria Cordova Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $335. If you aren’t able to travel during the month of March, then book flights to Medellín Jose Maria Cordova Intl Airport from Santiago during August instead. Flights to Medellín Jose Maria Cordova Intl Airport in August, while not as cheap as those in March, still average around $350.

What is the cheapest day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

The cheapest day to depart from Santiago to Medellín Jose Maria Cordova Intl Airport is on a Sunday. Travelers who choose to depart for Medellín Jose Maria Cordova Intl Airport on a Sunday will often find tickets for as low as $274. On the other hand, Thursday is the most expensive day to depart from Santiago because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $520.

What is the cheapest time of day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

Our data shows that the cheapest Santiago to Medellín Jose Maria Cordova Intl Airport flights are usually those with departure times in the morning. Our users have found flights to Medellín Jose Maria Cordova Intl Airport in the morning for as low as $383. In contrast, the most expensive time of day to depart to Medellín Jose Maria Cordova Intl Airport is in the evening when prices are around $472.

What is the cheapest Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl flight route?

Fly from Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl for the best Santiago Arturo Merino Benitez - Medellín Jose Maria Cordova Intl flight prices

How far in advance should I book a flight to Medellín Jose Maria Cordova Intl Airport?

You are more likely to see cheaper flights to Medellín Jose Maria Cordova Intl Airport from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Medellín Jose Maria Cordova Intl Airport for around $374 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Medellín Jose Maria Cordova Intl Airport from Santiago for as low as $323 on momondo.

What cabin class options are available on Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl flights?

There are 2 cabin classes available to choose from on Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santiago to Medellín Jose Maria Cordova Intl Airport flights?

No. A direct flight is the cheapest option for a flight between Santiago to Medellín Jose Maria Cordova Intl Airport.

How have Santiago to Medellín Jose Maria Cordova Intl Airport flight prices changed over time?

As of December 2025, prices for Santiago to Medellín Jose Maria Cordova Intl Airport flights are approximately 2% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to Medellín Jose Maria Cordova Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Medellín Jose Maria Cordova Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Medellín Jose Maria Cordova Intl Airport (SCL to MDE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Medellín Jose Maria Cordova Intl Airport

Best Price Found

$240

Fastest flight time

11h 49m

Direct flights

Every day
The best one-way flight to Medellín Jose Maria Cordova Intl Airport from Santiago in the past 72 hours is $240. The best round-trip flight deal from Santiago to Medellín Jose Maria Cordova Intl Airport found on momondo in the last 72 hours is $383.
The fastest flight from Santiago to Medellín Jose Maria Cordova Intl Airport takes 11h 49m
Direct flights go from Santiago to Medellín Jose Maria Cordova Intl Airport every day.
Search flight deals

  • How far is Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl by plane?

    There are 2752.8 mi between Santiago Arturo Merino Benitez and Medellín Jose Maria Cordova Intl. 11h 49m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport.

  • What documentation or ID do you need to fly to Medellín Jose Maria Cordova Intl Airport?

    The travel and health documents you'll need for your trip to Medellín Jose Maria Cordova Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Medellín Jose Maria Cordova Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santiago to Medellín Jose Maria Cordova Intl Airport?

  • What is the most popular airline from Santiago to Medellín Jose Maria Cordova Intl Airport?

Best airlines flying from Santiago to Medellín Jose Maria Cordova Intl Airport

Compare and see reviews for airlines that fly from Santiago to Medellín Jose Maria Cordova Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
JetSMARTPriceFrom $299Free CancellationRating
6.6
253 reviews
Search JetSMART flights
LATAM AirlinesPriceFrom $299Free CancellationRating
7.5
1,891 reviews
Search LATAM Airlines flights
AviancaPriceFrom $319Free CancellationRating
6.6
2,484 reviews
Search Avianca flights

  • JetSMART Flights From Santiago to Medellín Jose Maria Cordova Intl Airport

    JetSMART flies from Santiago to Medellín Jose Maria Cordova Intl Airport around 4 times per week, with 253 momondo users rating the airline 6.6/10. The cheapest JetSMART deal from Santiago to Medellín Jose Maria Cordova Intl Airport in the last 72 hours was $299 (round-trip), much lower than the average airfare cost of $364 for JetSMART flights on this route.

Traveling to a place near Medellín?

Book flights to Medellín if you plan to visit one of these locations
Guatapé
Rionegro

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Why should I use momondo to find a flight deal from Santiago to Medellín?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to Medellín. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to Medellín with flexible booking policies on momondo?

All flight searches from Santiago to Medellín on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to Medellín?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Medellín from Santiago.

I’m not ready to book a flight from Santiago to Medellín right now. Can momondo alert me if prices change?

Price alerts on flights to Medellín from Santiago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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