Cheap flights from Santiago to Medellín from $146

1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Santiago to Medellín

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetSMART Logo
10:34 am - 12:52 amSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
40h 18m2 stops Antofagasta Cerro Moreno Cali Alfonso B. Aragon Intl
JetSMART Logo
4:51 pm - 1:03 amMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
6h 12mnonstop
$291JetSMART
Wed, Jan 20 - Wed, Feb 3
JetSMART Logo
1:11 am - 6:35 amSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
6h 24mnonstop
JetSMART Logo
5:01 pm - 12:11 amMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
6h 10mnonstop
$292JetSMART
Mon, Apr 19 - Fri, Apr 30
JetSMART Logo
2:08 pm - 12:41 amSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
36h 33m2 stops Antofagasta Cerro Moreno Cali Alfonso B. Aragon Intl
JetSMART Logo
5:01 pm - 1:13 amMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
6h 12mnonstop
$293JetSMART
Mon, Mar 8 - Sat, Mar 27
JetSMART Logo
2:13 am - 6:28 amSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
6h 15mnonstop
JetSMART Logo
5:36 pm - 10:53 amMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
15h 17m1 stop Lima J Chavez Intl
$294JetSMART
Thu, Jan 28 - Tue, Feb 9
JetSMART Logo
12:32 pm - 4:46 pmSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
30h 14m1 stop Lima J Chavez Intl
JetSMART Logo
5:01 pm - 1:13 amMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
6h 12mnonstop
$294JetSMART
Tue, Dec 1 - Wed, Dec 9
JetSMART Logo
2:13 am - 6:28 amSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
6h 15mnonstop
JetSMART Logo
5:25 pm - 3:56 amMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
9h 31m1 stop Lima J Chavez Intl
$294JetSMART
Mon, Mar 22 - Tue, Apr 6
JetSMART Logo
6:07 am - 4:46 pmSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
12h 39m1 stop Lima J Chavez Intl
JetSMART Logo
4:51 pm - 1:03 amMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
6h 12mnonstop
$294JetSMART
Thu, Jan 28 - Tue, Feb 9
JetSMART Logo
2:13 am - 6:28 amSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
6h 15mnonstop
JetSMART Logo
10:27 pm - 12:08 amMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
23h 41m1 stop Bogotá El Dorado
$294JetSMART
Thu, Mar 4 - Fri, Mar 12
Copa Airlines Logo
3:48 am - 2:15 pmSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
12h 27m1 stop Panama City Tocumen Intl
Copa Airlines Logo
6:25 pm - 5:46 amMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
9h 21m1 stop Panama City Tocumen Intl
$425Copa Airlines
Thu, Nov 26 - Fri, Nov 27
LATAM Airlines Logo
4:35 pm - 8:05 amSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
17h 30m1 stop Bogotá El Dorado
LATAM Airlines Logo
11:25 pm - 3:00 pmMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
13h 35m2 stops Bogotá El Dorado Lima J Chavez Intl
$447LATAM Airlines
Thu, Dec 31 - Sat, Jan 16

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.

JetSMART flights from Santiago to Medellín Jose Maria Cordova Intl Airport

Our best JetSMART deals on Santiago to Medellín Jose Maria Cordova Intl Airport flight tickets
JetSMART
Jan 20
SCL10:34 amSantiago Arturo Merino Benitez
40h 18m
2 stops
MDE12:52 amMedellín Jose Maria Cordova Intl
Feb 3
MDE4:51 pmMedellín Jose Maria Cordova Intl
6h 12m
SCL1:03 amSantiago Arturo Merino Benitez
$291
JetSMART
Dec 1
SCL12:32 pmSantiago Arturo Merino Benitez
30h 14m
1 stop
MDE4:46 pmMedellín Jose Maria Cordova Intl
Dec 9
MDE5:01 pmMedellín Jose Maria Cordova Intl
6h 12m
SCL1:13 amSantiago Arturo Merino Benitez
$294
JetSMART
Jan 28
SCL10:12 pmSantiago Arturo Merino Benitez
20h 34m
1 stop
MDE4:46 pmMedellín Jose Maria Cordova Intl
Feb 9
MDE4:51 pmMedellín Jose Maria Cordova Intl
6h 12m
SCL1:03 amSantiago Arturo Merino Benitez
$295

Avianca flights from Santiago to Medellín Jose Maria Cordova Intl Airport

Our best Avianca deals on Santiago to Medellín Jose Maria Cordova Intl Airport flight tickets
Avianca
Nov 10
SCL4:15 pmSantiago Arturo Merino Benitez
9h 05m
1 stop
MDE11:20 pmMedellín Jose Maria Cordova Intl
Nov 12
MDE12:40 pmMedellín Jose Maria Cordova Intl
10h 25m
1 stop
SCL1:05 amSantiago Arturo Merino Benitez
$397
Avianca
Nov 8
SCL2:10 amSantiago Arturo Merino Benitez
11h 10m
1 stop
MDE11:20 amMedellín Jose Maria Cordova Intl
Nov 12
MDE5:05 pmMedellín Jose Maria Cordova Intl
10h 40m
1 stop
SCL5:45 amSantiago Arturo Merino Benitez
$417
Avianca
Nov 13
SCL8:55 amSantiago Arturo Merino Benitez
11h 50m
1 stop
MDE6:45 pmMedellín Jose Maria Cordova Intl
Nov 20
MDE2:05 pmMedellín Jose Maria Cordova Intl
9h 00m
1 stop
SCL1:05 amSantiago Arturo Merino Benitez
$418

momondo Fare Finder

 
Use the filters below to find and compare flights from Santiago to Medellín Jose Maria Cordova Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoMedellín

SCL Santiago Arturo Merino Benitez - MDE Medellín Jose Maria Cordova Intl

SCLMDE

Santiago Arturo Merino Benitez

Wed 1/20

10:34 am-12:52 am

2 stops40h 18m

Medellín Jose Maria Cordova Intl

Wed 2/3

4:51 pm-1:03 am

Nonstop6h 12m

$291
Quickest round-trip

SantiagoMedellín

SCL Santiago Arturo Merino Benitez - MDE Medellín Jose Maria Cordova Intl

SCLMDE

Santiago Arturo Merino Benitez

Mon 4/19

1:11 am-6:35 am

Nonstop6h 24m

Medellín Jose Maria Cordova Intl

Fri 4/30

5:01 pm-12:11 am

Nonstop6h 10m

$292

SantiagoMedellín

SCL Santiago Arturo Merino Benitez - MDE Medellín Jose Maria Cordova Intl

SCLMDE

Santiago Arturo Merino Benitez

Mon 3/8

2:08 pm-12:41 am

2 stops36h 33m

Medellín Jose Maria Cordova Intl

Sat 3/27

5:01 pm-1:13 am

Nonstop6h 12m

$293

SantiagoMedellín

SCL Santiago Arturo Merino Benitez - MDE Medellín Jose Maria Cordova Intl

SCLMDE

Santiago Arturo Merino Benitez

Thu 1/28

2:13 am-6:28 am

Nonstop6h 15m

Medellín Jose Maria Cordova Intl

Tue 2/9

5:36 pm-10:53 am

1 stop15h 17m

$294

SantiagoMedellín

SCL Santiago Arturo Merino Benitez - MDE Medellín Jose Maria Cordova Intl

SCLMDE

Santiago Arturo Merino Benitez

Tue 12/1

12:32 pm-4:46 pm

1 stop30h 14m

Medellín Jose Maria Cordova Intl

Wed 12/9

5:01 pm-1:13 am

Nonstop6h 12m

$294

SantiagoMedellín

SCL Santiago Arturo Merino Benitez - MDE Medellín Jose Maria Cordova Intl

SCLMDE

Santiago Arturo Merino Benitez

Mon 3/22

2:13 am-6:28 am

Nonstop6h 15m

Medellín Jose Maria Cordova Intl

Tue 4/6

5:25 pm-3:56 am

1 stop9h 31m

$294

SantiagoMedellín

SCL Santiago Arturo Merino Benitez - MDE Medellín Jose Maria Cordova Intl

SCLMDE

Santiago Arturo Merino Benitez

Thu 1/28

6:07 am-4:46 pm

1 stop12h 39m

Medellín Jose Maria Cordova Intl

Tue 2/9

4:51 pm-1:03 am

Nonstop6h 12m

$294

SantiagoMedellín

SCL Santiago Arturo Merino Benitez - MDE Medellín Jose Maria Cordova Intl

SCLMDE

Santiago Arturo Merino Benitez

Thu 3/4

2:13 am-6:28 am

Nonstop6h 15m

Medellín Jose Maria Cordova Intl

Fri 3/12

10:27 pm-12:08 am

1 stop23h 41m

$294

SantiagoMedellín

SCL Santiago Arturo Merino Benitez - MDE Medellín Jose Maria Cordova Intl

SCLMDE

Santiago Arturo Merino Benitez

Thu 11/26

3:48 am-2:15 pm

1 stop12h 27m

Medellín Jose Maria Cordova Intl

Fri 11/27

6:25 pm-5:46 am

1 stop9h 21m

$425

SantiagoMedellín

SCL Santiago Arturo Merino Benitez - MDE Medellín Jose Maria Cordova Intl

SCLMDE

Santiago Arturo Merino Benitez

Thu 12/31

4:35 pm-8:05 am

1 stop17h 30m

Medellín Jose Maria Cordova Intl

Sat 1/16

11:25 pm-3:00 pm

2 stops13h 35m

$447

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Medellín from

How to get the cheapest flight ticket from Santiago to Medellín Jose Maria Cordova Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and Medellín Jose Maria Cordova Intl Airport?

Prices are currently low for flights on this route.

Typical prices usually range from $324 to $410.
The lowest price recently found on this route was $291.

What is the cheapest month to fly to Medellín Jose Maria Cordova Intl Airport?

In general, March is the cheapest month to fly from Santiago to Medellín Jose Maria Cordova Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $341. If you aren’t able to travel during the month of March, then book flights to Medellín Jose Maria Cordova Intl Airport from Santiago during May instead. Flights to Medellín Jose Maria Cordova Intl Airport in May, while not as cheap as those in March, still average around $346.

What is the cheapest day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

The cheapest day to depart from Santiago to Medellín Jose Maria Cordova Intl Airport is on a Wednesday. Travelers who choose to depart for Medellín Jose Maria Cordova Intl Airport on a Wednesday will often find tickets for as low as $375. On the other hand, Sunday is the most expensive day to depart from Santiago because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $722.

What is the cheapest Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl flight route?

Fly from Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl for the best Santiago Arturo Merino Benitez - Medellín Jose Maria Cordova Intl flight prices

How far in advance should I book a flight from Santiago to Medellín Jose Maria Cordova Intl Airport?

You are more likely to see cheaper flights to Medellín Jose Maria Cordova Intl Airport from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Medellín Jose Maria Cordova Intl Airport for around $392 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Medellín Jose Maria Cordova Intl Airport from Santiago for as low as $336 on momondo.

What cabin class options are available on Santiago to Medellín Jose Maria Cordova Intl Airport flights?

There is only 1 cabin class available to choose from on Santiago to Medellín Jose Maria Cordova Intl Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santiago to Medellín Jose Maria Cordova Intl Airport flights?

You could potentially save up to 20% on your flight if you consider stops on a Santiago to Medellín Jose Maria Cordova Intl Airport flight.

How have Santiago to Medellín Jose Maria Cordova Intl Airport flight prices changed over time?

As of November 2026, prices for Santiago to Medellín Jose Maria Cordova Intl Airport flights are approximately 7% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to Medellín Jose Maria Cordova Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Medellín Jose Maria Cordova Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Medellín Jose Maria Cordova Intl Airport (SCL to MDE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Medellín Jose Maria Cordova Intl Airport

Best Price Found

$146

Fastest flight time

6h 15m

Direct flights

Every day
The best one-way flight to Medellín Jose Maria Cordova Intl Airport from Santiago in the past 72 hours is $146. The best round-trip flight deal from Santiago to Medellín Jose Maria Cordova Intl Airport found on momondo in the last 72 hours is $291.
The fastest flight from Santiago to Medellín Jose Maria Cordova Intl Airport takes 6h 15m
Direct flights go from Santiago to Medellín Jose Maria Cordova Intl Airport every day.

Frequently asked questions about flying from Santiago to Medellín Jose Maria Cordova Intl Airport

  • How far is Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl by plane?

    There are 2752.8 mi between Santiago Arturo Merino Benitez and Medellín Jose Maria Cordova Intl. 6h 15m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport.

  • What documentation or ID do you need to fly to Medellín Jose Maria Cordova Intl Airport?

    The travel and health documents you'll need for your trip to Medellín Jose Maria Cordova Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Medellín Jose Maria Cordova Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santiago to Medellín Jose Maria Cordova Intl Airport?

  • What is the most popular airline from Santiago to Medellín Jose Maria Cordova Intl Airport?

Best airlines flying from Santiago to Medellín Jose Maria Cordova Intl Airport

Compare and see reviews for airlines that fly from Santiago to Medellín Jose Maria Cordova Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
JetSMARTPriceFrom $213Free CancellationRating
6.9
350 reviews
Search JetSMART flights
  • JetSMART Flights From Santiago to Medellín Jose Maria Cordova Intl Airport

    JetSMART flies from Santiago to Medellín Jose Maria Cordova Intl Airport around 3 times per week, with 351 momondo users rating the airline 6.9/10. The cheapest JetSMART deal from Santiago to Medellín Jose Maria Cordova Intl Airport in the last 72 hours was $213 (round-trip), much lower than the average airfare cost of $394 for JetSMART flights on this route.

Traveling to a place near Medellín?

Book flights to Medellín if you plan to visit one of these locations
Guatapé
Rionegro

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Medellín?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to Medellín. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to Medellín with flexible booking policies on momondo?

All flight searches from Santiago to Medellín on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to Medellín?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Medellín from Santiago.

I’m not ready to book a flight from Santiago to Medellín right now. Can momondo alert me if prices change?

Price alerts on flights to Medellín from Santiago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Medellín Jose Maria Cordova Intl Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 12/8
Tue 12/15

Find better results for your trip to Medellín

Popular cities in Colombia