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Cheap flights from Santiago to Medellín from $166

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Medellín departing on 3/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Santiago to Medellín

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetSMART Logo
9:54 am - 5:01 pm
SCL
-
MDE
32h 07m
2 stops
JetSMART Logo
5:01 pm - 12:11 am
MDE
-
SCL
6h 10mnonstop
$324JetSMART
ven., mai 1 - ven., mai 15
JetSMART Logo
5:01 am - 4:50 pm
SCL
-
MDE
12h 49m
1 stop
JetSMART Logo
5:01 pm - 12:11 am
MDE
-
SCL
6h 10mnonstop
$325JetSMART
lun., mai 4 - ven., mai 29
JetSMART Logo
1:11 am - 6:35 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
3:11 pm - 3:55 pm
MDE
-
SCL
47h 44m
2 stops
$326JetSMART
dim., mai 3 - ven., mai 29
JetSMART Logo
1:11 am - 6:35 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
5:01 pm - 12:11 am
MDE
-
SCL
6h 10mnonstop
$327JetSMART
lun., avr. 13 - dim., avr. 26
JetSMART Logo
3:30 pm - 5:01 pm
SCL
-
MDE
26h 31m
1 stop
JetSMART Logo
5:01 pm - 12:11 am
MDE
-
SCL
6h 10mnonstop
$328JetSMART
ven., mai 1 - ven., mai 29
JetSMART Logo
2:09 am - 6:24 am
SCL
-
MDE
6h 15mnonstop
JetSMART Logo
5:01 pm - 12:11 am
MDE
-
SCL
6h 10mnonstop
$329JetSMART
jeu., mars 26 - ven., avr. 17
JetSMART Logo
1:11 am - 6:35 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
2:45 pm - 4:17 am
MDE
-
SCL
12h 32m
1 stop
$330JetSMART
dim., mai 17 - dim., mai 24
JetSMART Logo
1:11 am - 6:35 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
8:10 am - 2:29 pm
MDE
-
SCL
29h 19m
2 stops
$331JetSMART
ven., mai 8 - jeu., mai 21
JetSMART Logo
3:30 pm - 11:21 pm
SCL
-
MDE
33h 51m
2 stops
JetSMART Logo
5:01 pm - 1:09 am
MDE
-
SCL
6h 08mnonstop
$332JetSMART
ven., mars 13 - lun., mars 23
JetSMART Logo
1:11 am - 6:35 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
5:00 pm - 12:08 am
MDE
-
SCL
6h 08mnonstop
$333JetSMART
lun., juin 29 - lun., juil. 6

JetSMART flights from Santiago to Medellín Jose Maria Cordova Intl Airport

Our best JetSMART deals on Santiago to Medellín Jose Maria Cordova Intl Airport flight tickets
JetSMART
May 1
SCL9:54 amSantiago Arturo Merino Benitez
32h 07m
2 stops
MDE5:01 pmMedellín Jose Maria Cordova Intl
May 15
MDE5:01 pmMedellín Jose Maria Cordova Intl
6h 10m
SCL12:11 amSantiago Arturo Merino Benitez
$324
JetSMART
May 4
SCL5:01 amSantiago Arturo Merino Benitez
12h 49m
1 stop
MDE4:50 pmMedellín Jose Maria Cordova Intl
May 29
MDE5:01 pmMedellín Jose Maria Cordova Intl
6h 10m
SCL12:11 amSantiago Arturo Merino Benitez
$325
JetSMART
May 3
SCL1:11 amSantiago Arturo Merino Benitez
6h 24m
MDE6:35 amMedellín Jose Maria Cordova Intl
May 29
MDE3:11 pmMedellín Jose Maria Cordova Intl
47h 44m
2 stops
SCL3:55 pmSantiago Arturo Merino Benitez
$326

LATAM Airlines flights from Santiago to Medellín Jose Maria Cordova Intl Airport

Our best LATAM Airlines deals on Santiago to Medellín Jose Maria Cordova Intl Airport flight tickets
LATAM Airlines
Mar 27
SCL3:00 pmSantiago Arturo Merino Benitez
14h 05m
1 stop
MDE3:05 amMedellín Jose Maria Cordova Intl
Apr 17
MDE10:10 pmMedellín Jose Maria Cordova Intl
14h 35m
2 stops
SCL1:45 pmSantiago Arturo Merino Benitez
$357
LATAM Airlines
Apr 13
SCL4:30 pmSantiago Arturo Merino Benitez
14h 45m
1 stop
MDE6:15 amMedellín Jose Maria Cordova Intl
Apr 22
MDE8:50 amMedellín Jose Maria Cordova Intl
11h 05m
2 stops
SCL8:55 pmSantiago Arturo Merino Benitez
$363
LATAM Airlines
Jul 23
SCL5:40 amSantiago Arturo Merino Benitez
11h 40m
1 stop
MDE4:20 pmMedellín Jose Maria Cordova Intl
Jul 26
MDE6:15 pmMedellín Jose Maria Cordova Intl
10h 10m
1 stop
SCL5:25 amSantiago Arturo Merino Benitez
$364

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Medellín Jose Maria Cordova Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated janvier 29, 2026.
Use the filters below to find and compare flights from Santiago to Medellín Jose Maria Cordova Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

ven. 5/1

9:54 am-5:01 pm

2 stops32h 07m

Medellín Jose Maria Cordova Intl

ven. 5/15

5:01 pm-12:11 am

Nonstop6h 10m

$324

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

lun. 5/4

5:01 am-4:50 pm

1 stop12h 49m

Medellín Jose Maria Cordova Intl

ven. 5/29

5:01 pm-12:11 am

Nonstop6h 10m

$325

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

dim. 5/3

1:11 am-6:35 am

Nonstop6h 24m

Medellín Jose Maria Cordova Intl

ven. 5/29

3:11 pm-3:55 pm

2 stops47h 44m

$326

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

lun. 4/13

1:11 am-6:35 am

Nonstop6h 24m

Medellín Jose Maria Cordova Intl

dim. 4/26

5:01 pm-12:11 am

Nonstop6h 10m

$327

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

ven. 5/1

3:30 pm-5:01 pm

1 stop26h 31m

Medellín Jose Maria Cordova Intl

ven. 5/29

5:01 pm-12:11 am

Nonstop6h 10m

$328

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

jeu. 3/26

2:09 am-6:24 am

Nonstop6h 15m

Medellín Jose Maria Cordova Intl

ven. 4/17

5:01 pm-12:11 am

Nonstop6h 10m

$329

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

dim. 5/17

1:11 am-6:35 am

Nonstop6h 24m

Medellín Jose Maria Cordova Intl

dim. 5/24

2:45 pm-4:17 am

1 stop12h 32m

$330

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

ven. 5/8

1:11 am-6:35 am

Nonstop6h 24m

Medellín Jose Maria Cordova Intl

jeu. 5/21

8:10 am-2:29 pm

2 stops29h 19m

$331

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

ven. 3/13

3:30 pm-11:21 pm

2 stops33h 51m

Medellín Jose Maria Cordova Intl

lun. 3/23

5:01 pm-1:09 am

Nonstop6h 08m

$332

SantiagoMedellín

SCL - MDE

SCLMDE

Santiago Arturo Merino Benitez

lun. 6/29

1:11 am-6:35 am

Nonstop6h 24m

Medellín Jose Maria Cordova Intl

lun. 7/6

5:00 pm-12:08 am

Nonstop6h 08m

$333

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Santiago to Medellín Jose Maria Cordova Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and Medellín Jose Maria Cordova Intl Airport?

What is the cheapest month to fly to Medellín Jose Maria Cordova Intl Airport?

In general, March is the cheapest month to fly from Santiago to Medellín Jose Maria Cordova Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $337. If you aren’t able to travel during the month of March, then book flights to Medellín Jose Maria Cordova Intl Airport from Santiago during August instead. Flights to Medellín Jose Maria Cordova Intl Airport in August, while not as cheap as those in March, still average around $350.

What is the cheapest day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

The cheapest day to depart from Santiago to Medellín Jose Maria Cordova Intl Airport is on a Sunday. Travelers who choose to depart for Medellín Jose Maria Cordova Intl Airport on a Sunday will often find tickets for as low as $274. On the other hand, Thursday is the most expensive day to depart from Santiago because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $556.

What is the cheapest time of day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

Our data shows that the cheapest Santiago to Medellín Jose Maria Cordova Intl Airport flights are usually those with departure times in the morning. Our users have found flights to Medellín Jose Maria Cordova Intl Airport in the morning for as low as $356. In contrast, the most expensive time of day to depart to Medellín Jose Maria Cordova Intl Airport is in the evening when prices are around $458.

What is the cheapest Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl flight route?

Fly from Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl for the best Santiago Arturo Merino Benitez - Medellín Jose Maria Cordova Intl flight prices

How far in advance should I book a flight to Medellín Jose Maria Cordova Intl Airport?

You are more likely to see cheaper flights to Medellín Jose Maria Cordova Intl Airport from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Medellín Jose Maria Cordova Intl Airport for around $374 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Medellín Jose Maria Cordova Intl Airport from Santiago for as low as $322 on momondo.

What cabin class options are available on Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl flights?

There are 2 cabin classes available to choose from on Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santiago to Medellín Jose Maria Cordova Intl Airport flights?

No. A direct flight is the cheapest option for a flight between Santiago to Medellín Jose Maria Cordova Intl Airport.

How have Santiago to Medellín Jose Maria Cordova Intl Airport flight prices changed over time?

As of January 2026, prices for Santiago to Medellín Jose Maria Cordova Intl Airport flights are approximately 25% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to Medellín Jose Maria Cordova Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Medellín Jose Maria Cordova Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Medellín Jose Maria Cordova Intl Airport (SCL to MDE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Medellín Jose Maria Cordova Intl Airport

Fastest flight time

11h 28m

Direct flights

Every day
The fastest flight from Santiago to Medellín Jose Maria Cordova Intl Airport takes 11h 28m
Direct flights go from Santiago to Medellín Jose Maria Cordova Intl Airport every day.
Search flight deals

  • How far is Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl by plane?

    There are 2752.8 mi between Santiago Arturo Merino Benitez and Medellín Jose Maria Cordova Intl. 11h 28m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport.

  • What documentation or ID do you need to fly to Medellín Jose Maria Cordova Intl Airport?

    The travel and health documents you'll need for your trip to Medellín Jose Maria Cordova Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Medellín Jose Maria Cordova Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santiago to Medellín Jose Maria Cordova Intl Airport?

  • What is the most popular airline from Santiago to Medellín Jose Maria Cordova Intl Airport?

Best airlines flying from Santiago to Medellín Jose Maria Cordova Intl Airport

Compare and see reviews for airlines that fly from Santiago to Medellín Jose Maria Cordova Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
JetSMARTPriceFrom $152Free CancellationRating
6.7
263 reviews
Search JetSMART flights
Copa AirlinesPriceFrom $175Free CancellationRating
7.5
1,560 reviews
Search Copa Airlines flights
AviancaPriceFrom $233Free CancellationRating
6.6
2,492 reviews
Search Avianca flights
LATAM AirlinesPriceFrom $315Free CancellationRating
7.5
1,918 reviews
Search LATAM Airlines flights

  • JetSMART Flights From Santiago to Medellín Jose Maria Cordova Intl Airport

    JetSMART flies from Santiago to Medellín Jose Maria Cordova Intl Airport around 6 times per week, with 263 momondo users rating the airline 6.7/10. The cheapest JetSMART deal from Santiago to Medellín Jose Maria Cordova Intl Airport in the last 72 hours was $152 (round-trip), much lower than the average airfare cost of $366 for JetSMART flights on this route.

Traveling to a place near Medellín?

Book flights to Medellín if you plan to visit one of these locations
Guatapé
Rionegro

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Why should I use momondo to find a flight deal from Santiago to Medellín?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to Medellín. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to Medellín with flexible booking policies on momondo?

All flight searches from Santiago to Medellín on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to Medellín?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Medellín from Santiago.

I’m not ready to book a flight from Santiago to Medellín right now. Can momondo alert me if prices change?

Price alerts on flights to Medellín from Santiago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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