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Cheap flights from Santiago to Guayaquil from $184

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Guayaquil departing on 9/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Copa Airlines Logo
4:19 am - 5:36 pmSCL-GYE
15h 17m1 stop
Copa Airlines Logo
8:18 am - 8:17 pmGYE-SCL
9h 59m1 stop
$381Copa Airlines
Find Deal
Sun, Nov 16 - Tue, Jan 20
Avianca Logo
6:55 am - 5:56 pmSCL-GYE
13h 01m2 stops
Avianca Logo
8:55 am - 11:40 pmGYE-SCL
12h 45m1 stop
$394Avianca
Find Deal
Thu, Nov 6 - Tue, Nov 11
Copa Airlines Logo
4:19 am - 8:35 pmSCL-GYE
18h 16m1 stop
Copa Airlines Logo
12:20 pm - 12:08 amGYE-SCL
9h 48m1 stop
$411Copa Airlines
Find Deal
Wed, Nov 5 - Tue, Nov 11
Avianca Logo
11:55 pm - 9:55 amSCL-GYE
11h 00m1 stop
Avianca Logo
3:20 pm - 4:15 amGYE-SCL
11h 55m2 stops
$415Avianca
Find Deal
Sat, Aug 16 - Fri, Aug 29
LATAM Airlines Logo
9:35 pm - 11:10 amSCL-GYE
14h 35m1 stop
LATAM Airlines Logo
2:45 pm - 8:38 pmGYE-SCL
4h 53mnonstop
$457LATAM Airlines
Find Deal
Fri, Aug 15 - Sun, Aug 17
LATAM Airlines Logo
11:50 pm - 4:13 amSCL-GYE
5h 23mnonstop
LATAM Airlines Logo
12:55 pm - 9:55 pmGYE-SCL
8h 00m1 stop
$460LATAM Airlines
Find Deal
Sat, Aug 16 - Fri, Aug 29
 Logo
5:17 pm - 11:10 amSCL-GYE
18h 53m2 stops
 Logo
3:35 am - 1:25 pmGYE-SCL
8h 50m1 stop
Fri, Aug 15 - Sat, Aug 16
 Logo
11:50 pm - 4:13 amSCL-GYE
5h 23mnonstop
 Logo
3:35 am - 1:25 pmGYE-SCL
8h 50m1 stop
Fri, Aug 15 - Sat, Aug 16
United Airlines Logo
10:45 pm - 2:45 amSCL-GYE
30h 00m2 stops
United Airlines Logo
2:49 pm - 8:50 amGYE-SCL
40h 01m2 stops
$1,786United Airlines
Find Deal
Tue, Nov 4 - Mon, Nov 17
United Airlines Logo
10:45 pm - 2:45 amSCL-GYE
30h 00m2 stops
United Airlines Logo
12:20 pm - 8:50 amGYE-SCL
42h 30m2 stops
$1,811United Airlines
Find Deal
Tue, Nov 4 - Sun, Nov 16

Copa Airlines flights from Santiago to Guayaquil

Our best Copa Airlines deals on Santiago to Guayaquil flight tickets
Copa Airlines
Nov 16
SCL4:19 amSantiago Arturo Merino Benitez
15h 17m
1 stop
GYE5:36 pmGuayaquil Jose Joaquin de Olmedo
Jan 20
GYE8:18 amGuayaquil Jose Joaquin de Olmedo
9h 59m
1 stop
SCL8:17 pmSantiago Arturo Merino Benitez
Copa Airlines
Nov 5
SCL4:19 amSantiago Arturo Merino Benitez
18h 16m
1 stop
GYE8:35 pmGuayaquil Jose Joaquin de Olmedo
Nov 11
GYE12:20 pmGuayaquil Jose Joaquin de Olmedo
9h 48m
1 stop
SCL12:08 amSantiago Arturo Merino Benitez
Copa Airlines
Aug 18
SCL4:10 amSantiago Arturo Merino Benitez
20h 47m
1 stop
GYE11:57 pmGuayaquil Jose Joaquin de Olmedo
Aug 25
GYE8:30 amGuayaquil Jose Joaquin de Olmedo
13h 38m
1 stop
SCL11:08 pmSantiago Arturo Merino Benitez

Avianca flights from Santiago to Guayaquil

Our best Avianca deals on Santiago to Guayaquil flight tickets
Avianca
Nov 6
SCL6:55 amSantiago Arturo Merino Benitez
13h 01m
2 stops
GYE5:56 pmGuayaquil Jose Joaquin de Olmedo
Nov 11
GYE8:55 amGuayaquil Jose Joaquin de Olmedo
12h 45m
1 stop
SCL11:40 pmSantiago Arturo Merino Benitez
Avianca
Aug 16
SCL11:55 pmSantiago Arturo Merino Benitez
11h 00m
1 stop
GYE9:55 amGuayaquil Jose Joaquin de Olmedo
Aug 29
GYE3:20 pmGuayaquil Jose Joaquin de Olmedo
11h 55m
2 stops
SCL4:15 amSantiago Arturo Merino Benitez
Avianca
Aug 16
SCL6:10 amSantiago Arturo Merino Benitez
12h 30m
2 stops
GYE5:40 pmGuayaquil Jose Joaquin de Olmedo
Aug 28
GYE3:35 amGuayaquil Jose Joaquin de Olmedo
8h 50m
1 stop
SCL1:25 pmSantiago Arturo Merino Benitez

See travel insights to Guayaquil from

How to get the cheapest flight ticket from Santiago to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and Guayaquil?

What is the cheapest month to fly to Guayaquil?

The month of November is another great option to travel to Guayaquil, with average flight prices from Santiago averaging around $343.

What is the cheapest day to depart on your flight to Guayaquil?

The cheapest day to depart from Santiago to Guayaquil is on a Monday. Travelers who choose to depart for Guayaquil on a Monday will often find tickets for as low as $377. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Guayaquil on Thursday is $693.

What is the cheapest time of day to depart on your flight to Guayaquil?

The cheapest time of day to fly to Guayaquil is in the morning when flights can be purchased for as low as $423. Flights to Guayaquil are more costly in the evening, with an average ticket price of $461. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo flight route?

Fly from Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo for the best Santiago Arturo Merino Benitez - Guayaquil Jose Joaquin de Olmedo flight prices

How far in advance should I book a flight to Guayaquil?

You are more likely to see cheaper flights to Guayaquil from Santiago when booking 16 weeks ahead of your departure date. In general, you can expect to find flights to Guayaquil for around $400 when searching 16 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Guayaquil from Santiago for as low as $356 on momondo.

What cabin class options are available on Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo flights?

There are 2 cabin classes available to choose from on Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Santiago to Guayaquil flight prices changed over time?

As of June 2025, prices for Santiago to Guayaquil flights are approximately 8% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Guayaquil (SCL to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Guayaquil

Best Price Found

$184

Fastest flight time

5h 16m

Direct flights

Mon, Tue, Thu, Sat and Sun

Airports in Guayaquil

1 airport
The best one-way flight to Guayaquil from Santiago in the past 72 hours is $184. The best round-trip flight deal from Santiago to Guayaquil found on momondo in the last 72 hours is $381.
The fastest flight from Santiago to Guayaquil takes 5h 16m
Direct flights go from Santiago to Guayaquil on Monday, Tuesday, Thursday, Saturday and Sunday. The only airline offering direct flights is LATAM Airlines.
There is 1 airport near Guayaquil: Guayaquil Jose Joaquin de Olmedo (GYE)

  • How far is Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo by plane?

    The distance between Santiago Arturo Merino Benitez and Guayaquil Jose Joaquin de Olmedo is about 2238.9 mi. In terms of flight time, this usually takes a little over 5h 16m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Guayaquil Jose Joaquin de Olmedo Airport were last updated today.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The required travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Guayaquil Jose Joaquin de Olmedo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Santiago to Guayaquil?

  • What is the most popular airline from Santiago to Guayaquil?


Best airlines flying from Santiago to Guayaquil

Compare and see reviews for airlines that fly from Santiago to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $299Free CancellationRating
7.5
1,785 reviews
Search LATAM Airlines flights
  • LATAM Airlines Flights From Santiago to Guayaquil

    The lowest priced LATAM Airlines flight from Santiago to Guayaquil from the last 72 hours was $299. Generally, LATAM Airlines has 6 flights on this route every week with an average price of $427. LATAM Airlines is rated 7.5/10 by our users.


Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Guayaquil?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to Guayaquil. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to Guayaquil with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Guayaquil from Santiago with this policy.

How can momondo help me find flights from Santiago to Guayaquil?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Santiago to Guayaquil.

I’m not ready to book a flight from Santiago to Guayaquil right now. Can momondo alert me if prices change?

Price alerts on flights to Guayaquil from Santiago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.


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Tue 6/17
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