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Cheap flights from Santa Cruz de la Sierra to Santiago from $420

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Cruz de la Sierra to Santiago departing on 4/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Santa Cruz de la Sierra to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
2:00 am - 5:25 pmVVI-SCL
15h 25m1 stop
Multiple Airlines Logo
12:10 pm - 3:25 pmSCL-VVI
3h 15mnonstop
$420Multiple Airlines
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Fri, Apr 24 - Sat, May 2
Multiple Airlines Logo
2:00 am - 5:25 pmVVI-SCL
15h 25m1 stop
Multiple Airlines Logo
6:40 pm - 4:35 amSCL-VVI
9h 55m1 stop
$432Multiple Airlines
Find Deal
Fri, Apr 24 - Sat, May 2
LATAM Airlines Logo
5:25 am - 10:30 pmVVI-SCL
17h 05m2 stops
LATAM Airlines Logo
5:32 am - 10:29 amSCL-VVI
4h 57m1 stop
$445LATAM Airlines
Find Deal
Sat, Apr 25 - Sat, May 2
BoA Logo
8:00 am - 11:15 amVVI-SCL
3h 15mnonstop
BoA Logo
12:10 pm - 3:25 pmSCL-VVI
3h 15mnonstop
$449BoA
Find Deal
Sat, Apr 25 - Sat, May 2
Multiple Airlines Logo
5:25 am - 4:30 pmVVI-SCL
11h 05m1 stop
Multiple Airlines Logo
3:55 pm - 1:10 amSCL-VVI
9h 15m1 stop
$450Multiple Airlines
Find Deal
Fri, May 15 - Fri, May 29
Multiple Airlines Logo
5:25 am - 4:30 pmVVI-SCL
11h 05m1 stop
Multiple Airlines Logo
12:10 pm - 3:25 pmSCL-VVI
3h 15mnonstop
$474Multiple Airlines
Find Deal
Fri, Apr 10 - Sat, Apr 18
LATAM Airlines Logo
7:26 am - 11:28 amVVI-SCL
3h 02mnonstop
LATAM Airlines Logo
3:00 pm - 4:35 amSCL-VVI
14h 35m1 stop
$490LATAM Airlines
Find Deal
Wed, Jan 21 - Wed, Jan 28
Multiple Airlines Logo
7:26 am - 11:28 amVVI-SCL
3h 02mnonstop
Multiple Airlines Logo
3:35 pm - 1:10 amSCL-VVI
10h 35m1 stop
$493Multiple Airlines
Find Deal
Wed, Mar 11 - Mon, Mar 16
Multiple Airlines Logo
1:00 pm - 10:05 pmVVI-SCL
32h 05m3 stops
Multiple Airlines Logo
3:35 pm - 1:10 amSCL-VVI
10h 35m1 stop
$499Multiple Airlines
Find Deal
Wed, Mar 11 - Mon, Mar 16
LATAM Airlines Logo
7:26 am - 11:28 amVVI-SCL
3h 02mnonstop
LATAM Airlines Logo
8:50 pm - 4:35 amSCL-VVI
8h 45m1 stop
$505LATAM Airlines
Find Deal
Wed, Feb 11 - Mon, Feb 16

LATAM Airlines flights from Santa Cruz de la Sierra to Santiago

Our best LATAM Airlines deals on Santa Cruz de la Sierra to Santiago flight tickets
LATAM Airlines
Apr 25
VVI5:25 amSanta Cruz de la Sierra Viru Viru Intl
17h 05m
2 stops
SCL10:30 pmSantiago Arturo Merino Benitez
May 2
SCL5:32 amSantiago Arturo Merino Benitez
4h 57m
1 stop
VVI10:29 amSanta Cruz de la Sierra Viru Viru Intl
$445
Find similar
LATAM Airlines
Jan 21
VVI7:26 amSanta Cruz de la Sierra Viru Viru Intl
3h 02m
SCL11:28 amSantiago Arturo Merino Benitez
Jan 28
SCL3:00 pmSantiago Arturo Merino Benitez
14h 35m
1 stop
VVI4:35 amSanta Cruz de la Sierra Viru Viru Intl
$490
Find similar
LATAM Airlines
Feb 11
VVI7:26 amSanta Cruz de la Sierra Viru Viru Intl
3h 02m
SCL11:28 amSantiago Arturo Merino Benitez
Feb 16
SCL8:50 pmSantiago Arturo Merino Benitez
8h 45m
1 stop
VVI4:35 amSanta Cruz de la Sierra Viru Viru Intl
$505
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 3, 2025.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Fri 4/24

2:00 am-5:25 pm

1 stop15h 25m

Santiago Arturo Merino Benitez

Sat 5/2

12:10 pm-3:25 pm

Nonstop3h 15m

$420

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Fri 4/24

2:00 am-5:25 pm

1 stop15h 25m

Santiago Arturo Merino Benitez

Sat 5/2

6:40 pm-4:35 am

1 stop9h 55m

$432

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Sat 4/25

5:25 am-10:30 pm

2 stops17h 05m

Santiago Arturo Merino Benitez

Sat 5/2

5:32 am-10:29 am

1 stop4h 57m

$445

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Sat 4/25

8:00 am-11:15 am

Nonstop3h 15m

Santiago Arturo Merino Benitez

Sat 5/2

12:10 pm-3:25 pm

Nonstop3h 15m

$449

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Fri 5/15

5:25 am-4:30 pm

1 stop11h 05m

Santiago Arturo Merino Benitez

Fri 5/29

3:55 pm-1:10 am

1 stop9h 15m

$450

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Fri 4/10

5:25 am-4:30 pm

1 stop11h 05m

Santiago Arturo Merino Benitez

Sat 4/18

12:10 pm-3:25 pm

Nonstop3h 15m

$474

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Wed 1/21

7:26 am-11:28 am

Nonstop3h 02m

Santiago Arturo Merino Benitez

Wed 1/28

3:00 pm-4:35 am

1 stop14h 35m

$490

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Wed 3/11

7:26 am-11:28 am

Nonstop3h 02m

Santiago Arturo Merino Benitez

Mon 3/16

3:35 pm-1:10 am

1 stop10h 35m

$493

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Wed 3/11

1:00 pm-10:05 pm

3 stops32h 05m

Santiago Arturo Merino Benitez

Mon 3/16

3:35 pm-1:10 am

1 stop10h 35m

$499

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Wed 2/11

7:26 am-11:28 am

Nonstop3h 02m

Santiago Arturo Merino Benitez

Mon 2/16

8:50 pm-4:35 am

1 stop8h 45m

$505

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santiago from

How to get the cheapest flight ticket from Santa Cruz de la Sierra to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santa Cruz de la Sierra and Santiago?

What is the cheapest month to fly to Santiago?

In general, March is the cheapest month to fly from Santa Cruz de la Sierra to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $464. If you don’t want to visit Santiago in March, then you should wait until September to fly from Santa Cruz de la Sierra, when ticket prices are also cheap, with an average price of $471.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $465. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Sunday is $609.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from Santa Cruz de la Sierra to Santiago when you can find flight prices for as low as $376. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $549 per ticket.

What is the cheapest Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez flight route?

Fly from Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez for the best Santa Cruz de la Sierra Viru Viru Intl - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Santa Cruz de la Sierra when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $509 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Santa Cruz de la Sierra for as low as $408 on momondo.

What cabin class options are available on Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez flights?

There are 2 cabin classes available to choose from on Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santa Cruz de la Sierra to Santiago flights?

No. A direct flight is the cheapest option for a flight between Santa Cruz de la Sierra to Santiago.

How have Santa Cruz de la Sierra to Santiago flight prices changed over time?

As of December 2025, prices for Santa Cruz de la Sierra to Santiago flights are approximately 16% more expensive when compared to flights at the same time last year.

When to book flights from Santa Cruz de la Sierra to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Cruz de la Sierra to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Cruz de la Sierra to Santiago (VVI to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Cruz de la Sierra to Santiago

Best Price Found

$522

Fastest flight time

3h 02m

Direct flights

Tue, Thu and Sun

Airports in Santiago

1 airport
The best flight deal from Santa Cruz de la Sierra to Santiago found on momondo in the last 72 hours is $522
The fastest flight from Santa Cruz de la Sierra to Santiago takes 3h 02m
Direct flights go from Santa Cruz de la Sierra to Santiago on Tuesday, Thursday and Sunday. There are no airlines offering direct flights.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)
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  • How far is Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez by plane?

    A flight from Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez will travel around 1175.2 mi. 3h 02m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Santa Cruz de la Sierra Viru Viru Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Cruz de la Sierra Viru Viru Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Santa Cruz de la Sierra to Santiago?

  • What is the most popular airline from Santa Cruz de la Sierra to Santiago?

Best airlines flying from Santa Cruz de la Sierra to Santiago

Compare and see reviews for airlines that fly from Santa Cruz de la Sierra to Santiago with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $290Free CancellationRating
7.5
1,890 reviews
Search LATAM Airlines flights

  • LATAM Airlines Flights From Santa Cruz de la Sierra to Santiago

    LATAM Airlines operates around 1 flight from Santa Cruz de la Sierra to Santiago every week. The average price of these flights found in the last 72 hours has been $521, but momondo users have found LATAM Airlines deals from Santa Cruz de la Sierra to Santiago from as low as $290 round-trip. LATAM Airlines has been scored 7.5/10 in 1,890 reviews.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Santa Cruz de la Sierra to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santa Cruz de la Sierra to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santa Cruz de la Sierra to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Santa Cruz de la Sierra which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santa Cruz de la Sierra to Santiago?

momondo helps you find the best flight between Santa Cruz de la Sierra and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santa Cruz de la Sierra to Santiago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago, momondo offers a useful price alert feature which will track prices for flights to Santiago from Santa Cruz de la Sierra and alert you when they change.

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