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Cheap flights from Santa Cruz de la Sierra to Santiago from $291

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Cruz de la Sierra to Santiago departing on 3/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Santa Cruz de la Sierra to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
5:25 am - 11:18 pm
VVI
-
SCL
16h 53m
2 stops
LATAM Airlines Logo
6:28 am - 10:30 am
SCL
-
VVI
5h 02m
1 stop
$456LATAM Airlines
Mon, Mar 23 - Sat, Mar 28
Multiple Airlines Logo
5:25 am - 4:30 pm
VVI
-
SCL
11h 05m
1 stop
Multiple Airlines Logo
2:35 pm - 1:10 am
SCL
-
VVI
10h 35m
1 stop
$471Multiple Airlines
Fri, May 15 - Fri, May 29
LATAM Airlines Logo
5:25 am - 3:30 pm
VVI
-
SCL
9h 05m
1 stop
LATAM Airlines Logo
6:32 am - 10:28 am
SCL
-
VVI
4h 56m
1 stop
$476LATAM Airlines
Mon, Mar 23 - Sat, Mar 28
Multiple Airlines Logo
5:25 am - 5:25 pm
VVI
-
SCL
12h 00m
1 stop
Multiple Airlines Logo
8:50 pm - 1:10 am
SCL
-
VVI
28h 20m
1 stop
$481Multiple Airlines
Thu, May 7 - Sun, May 10
LATAM Airlines Logo
7:26 am - 11:28 am
VVI
-
SCL
3h 02mnonstop
LATAM Airlines Logo
5:32 am - 10:29 am
SCL
-
VVI
4h 57m
1 stop
$494LATAM Airlines
Wed, Mar 11 - Thu, Apr 9
LATAM Airlines Logo
10:43 am - 2:45 pm
VVI
-
SCL
3h 02mnonstop
LATAM Airlines Logo
4:36 am - 7:56 am
SCL
-
VVI
3h 20mnonstop
$496LATAM Airlines
Sun, Mar 8 - Wed, Apr 15
Multiple Airlines Logo
10:43 am - 2:45 pm
VVI
-
SCL
3h 02mnonstop
Multiple Airlines Logo
8:50 pm - 1:10 am
SCL
-
VVI
28h 20m
1 stop
$497Multiple Airlines
Sun, Mar 8 - Sun, Apr 12
LATAM Airlines Logo
10:41 am - 2:45 pm
VVI
-
SCL
3h 04mnonstop
LATAM Airlines Logo
12:35 pm - 4:35 am
SCL
-
VVI
16h 00m
1 stop
$508LATAM Airlines
Sun, Mar 8 - Sun, Apr 12
Multiple Airlines Logo
5:25 am - 8:55 pm
VVI
-
SCL
15h 30m
1 stop
Multiple Airlines Logo
6:40 am - 2:30 am
SCL
-
VVI
19h 50m
1 stop
$511Multiple Airlines
Fri, Apr 10 - Sat, Apr 18
LATAM Airlines Logo
11:14 am - 3:16 pm
VVI
-
SCL
3h 02mnonstop
LATAM Airlines Logo
7:45 pm - 4:35 am
SCL
-
VVI
8h 50m
1 stop
$515LATAM Airlines
Sat, Mar 7 - Fri, Apr 10

LATAM Airlines flights from Santa Cruz de la Sierra to Santiago

Our best LATAM Airlines deals on Santa Cruz de la Sierra to Santiago flight tickets
LATAM Airlines
Mar 23
VVI5:25 amSanta Cruz de la Sierra Viru Viru Intl
16h 53m
2 stops
SCL11:18 pmSantiago Arturo Merino Benitez
Mar 28
SCL6:28 amSantiago Arturo Merino Benitez
5h 02m
1 stop
VVI10:30 amSanta Cruz de la Sierra Viru Viru Intl
$456
LATAM Airlines
Mar 23
VVI5:25 amSanta Cruz de la Sierra Viru Viru Intl
9h 05m
1 stop
SCL3:30 pmSantiago Arturo Merino Benitez
Mar 28
SCL6:32 amSantiago Arturo Merino Benitez
4h 56m
1 stop
VVI10:28 amSanta Cruz de la Sierra Viru Viru Intl
$476
LATAM Airlines
Mar 11
VVI7:26 amSanta Cruz de la Sierra Viru Viru Intl
3h 02m
SCL11:28 amSantiago Arturo Merino Benitez
Apr 9
SCL5:32 amSantiago Arturo Merino Benitez
4h 57m
1 stop
VVI10:29 amSanta Cruz de la Sierra Viru Viru Intl
$494

Aerolineas Argentinas flights from Santa Cruz de la Sierra to Santiago

Our best Aerolineas Argentinas deals on Santa Cruz de la Sierra to Santiago flight tickets
Aerolineas Argentinas
Mar 9
VVI2:00 amSanta Cruz de la Sierra Viru Viru Intl
11h 25m
1 stop
SCL2:25 pmSantiago Arturo Merino Benitez
Apr 10
SCL6:35 pmSantiago Arturo Merino Benitez
6h 35m
1 stop
VVI1:10 amSanta Cruz de la Sierra Viru Viru Intl
$538
Aerolineas Argentinas
Mar 6
VVI2:00 amSanta Cruz de la Sierra Viru Viru Intl
15h 05m
1 stop
SCL6:05 pmSantiago Arturo Merino Benitez
Apr 13
SCL2:35 pmSantiago Arturo Merino Benitez
10h 35m
1 stop
VVI1:10 amSanta Cruz de la Sierra Viru Viru Intl
$571
Aerolineas Argentinas
Mar 6
VVI2:00 amSanta Cruz de la Sierra Viru Viru Intl
16h 05m
1 stop
SCL7:05 pmSantiago Arturo Merino Benitez
Apr 12
SCL8:50 pmSantiago Arturo Merino Benitez
28h 20m
1 stop
VVI1:10 amSanta Cruz de la Sierra Viru Viru Intl
$581

momondo Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/23

5:25 am-11:18 pm

2 stops16h 53m

Santiago Arturo Merino Benitez

Sat 3/28

6:28 am-10:30 am

1 stop5h 02m

$456

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Fri 5/15

5:25 am-4:30 pm

1 stop11h 05m

Santiago Arturo Merino Benitez

Fri 5/29

2:35 pm-1:10 am

1 stop10h 35m

$471

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/23

5:25 am-3:30 pm

1 stop9h 05m

Santiago Arturo Merino Benitez

Sat 3/28

6:32 am-10:28 am

1 stop4h 56m

$476

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Thu 5/7

5:25 am-5:25 pm

1 stop12h 00m

Santiago Arturo Merino Benitez

Sun 5/10

8:50 pm-1:10 am

1 stop28h 20m

$481

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Wed 3/11

7:26 am-11:28 am

Nonstop3h 02m

Santiago Arturo Merino Benitez

Thu 4/9

5:32 am-10:29 am

1 stop4h 57m

$494

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Sun 3/8

10:43 am-2:45 pm

Nonstop3h 02m

Santiago Arturo Merino Benitez

Wed 4/15

4:36 am-7:56 am

Nonstop3h 20m

$496

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Sun 3/8

10:43 am-2:45 pm

Nonstop3h 02m

Santiago Arturo Merino Benitez

Sun 4/12

8:50 pm-1:10 am

1 stop28h 20m

$497

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Sun 3/8

10:41 am-2:45 pm

Nonstop3h 04m

Santiago Arturo Merino Benitez

Sun 4/12

12:35 pm-4:35 am

1 stop16h 00m

$508

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Fri 4/10

5:25 am-8:55 pm

1 stop15h 30m

Santiago Arturo Merino Benitez

Sat 4/18

6:40 am-2:30 am

1 stop19h 50m

$511

Santa Cruz de la SierraSantiago

VVI - SCL

VVISCL

Santa Cruz de la Sierra Viru Viru Intl

Sat 3/7

11:14 am-3:16 pm

Nonstop3h 02m

Santiago Arturo Merino Benitez

Fri 4/10

7:45 pm-4:35 am

1 stop8h 50m

$515

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Santa Cruz de la Sierra to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santa Cruz de la Sierra and Santiago?

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Santa Cruz de la Sierra to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $471. If you don’t want to visit Santiago in September, then you should wait until October to fly from Santa Cruz de la Sierra, when ticket prices are also cheap, with an average price of $486.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $478. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $759.

What is the cheapest Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez flight route?

Fly from Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez for the best Santa Cruz de la Sierra Viru Viru Intl - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Santa Cruz de la Sierra when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $528 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Santa Cruz de la Sierra for as low as $421 on momondo.

What cabin class options are available on Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez flights?

There is only 1 cabin class available to choose from on Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santa Cruz de la Sierra to Santiago flights?

You could potentially save up to 8% on your flight if you consider stops on a Santa Cruz de la Sierra to Santiago flight.

How have Santa Cruz de la Sierra to Santiago flight prices changed over time?

As of January 2026, prices for Santa Cruz de la Sierra to Santiago flights are approximately 23% more expensive when compared to flights at the same time last year.

When to book flights from Santa Cruz de la Sierra to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Cruz de la Sierra to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Cruz de la Sierra to Santiago (VVI to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Cruz de la Sierra to Santiago

Best Price Found

$292

Fastest flight time

3h 02m

Direct flights

Mon, Tue, Thu, Fri and Sun

Airports in Santiago

1 airport
The best one-way flight to Santiago from Santa Cruz de la Sierra in the past 72 hours is $292. The best round-trip flight deal from Santa Cruz de la Sierra to Santiago found on momondo in the last 72 hours is $465.
The fastest flight from Santa Cruz de la Sierra to Santiago takes 3h 02m
Direct flights go from Santa Cruz de la Sierra to Santiago on Monday, Tuesday, Thursday, Friday and Sunday. There are no airlines offering direct flights.
There is 1 airport in Santiago. From Santa Cruz de la Sierra there are direct flights to Santiago Arturo Merino Benitez (SCL).
Search flight deals

  • How far is Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez by plane?

    A flight from Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez will travel around 1175.2 mi. 3h 02m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Santa Cruz de la Sierra Viru Viru Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Cruz de la Sierra Viru Viru Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Santa Cruz de la Sierra to Santiago?

  • What is the most popular airline from Santa Cruz de la Sierra to Santiago?

Best airlines flying from Santa Cruz de la Sierra to Santiago

Compare and see reviews for airlines that fly from Santa Cruz de la Sierra to Santiago with momondo
Airline
Rating
Free Cancellation
Price
Aerolineas ArgentinasPriceFrom $267Free CancellationRating
8.0
1,007 reviews
Search Aerolineas Argentinas flights
LATAM AirlinesPriceFrom $465Free CancellationRating
7.5
1,918 reviews
Search LATAM Airlines flights

  • LATAM Airlines Flights From Santa Cruz de la Sierra to Santiago

    LATAM Airlines operates around 1 flight from Santa Cruz de la Sierra to Santiago every week. The average price of these flights found in the last 72 hours has been $567, but momondo users have found LATAM Airlines deals from Santa Cruz de la Sierra to Santiago from as low as $465 round-trip. LATAM Airlines has been scored 7.5/10 in 1,918 reviews.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Santa Cruz de la Sierra to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santa Cruz de la Sierra to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santa Cruz de la Sierra to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Santa Cruz de la Sierra which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santa Cruz de la Sierra to Santiago?

momondo helps you find the best flight between Santa Cruz de la Sierra and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santa Cruz de la Sierra to Santiago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago, momondo offers a useful price alert feature which will track prices for flights to Santiago from Santa Cruz de la Sierra and alert you when they change.

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