Cheap flights from Santa Cruz de la Sierra to Santiago from $245

In general, September is the cheapest month to fly from Santa Cruz de la Sierra to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $372. If you don’t want to visit Santiago in September, then you should wait until August to fly from Santa Cruz de la Sierra, when ticket prices are also cheap, with an average price of $374.

The cheapest day to depart on your flight to Santiago is on a Friday when prices can be found for as low as $372. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Sunday is $1,156.

In the evening is the cheapest time of day to fly from Santa Cruz de la Sierra to Santiago when you can find flight prices for as low as $372. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $567 per ticket.

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You are more likely to see cheaper flights to Santiago from Santa Cruz de la Sierra when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $470 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Santa Cruz de la Sierra for as low as $344 on momondo.

There is only 1 cabin class available to choose from on Santa Cruz de la Sierra to Santiago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Santa Cruz de la Sierra to Santiago.

As of October 2026, prices for Santa Cruz de la Sierra to Santiago flights are approximately 44% cheaper when compared to flights at the same time last year.

Historically, on average around 20% of flights between Santa Cruz de la Sierra and Santiago have experienced a delay on any given week. The average delay length over the past 12 months has been 101 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

Wednesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Monday has historically seen more delays on average compared to the rest of the week.

According to our data, LATAM Airlines have had the least number of delays on this route over the last 12 months; with about 9% of their flights experiencing any sort of delay.