Cheap flights from Raleigh to Panama City from $221

In general, October is the cheapest month to fly from Raleigh to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $398. If you’re not able to fly to Panama City in October, then September is your next best option. Flight prices from Raleigh to Panama City during September average around $403.

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $397. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $738. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

Fly from Raleigh-Durham to Panama City Tocumen Intl for the best Raleigh-Durham - Panama City Tocumen Intl flight prices

You are more likely to see cheaper flights to Panama City from Raleigh when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $547 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Raleigh for as low as $353 on momondo.

There are 3 cabin classes available to choose from on Raleigh to Panama City flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 18% on your flight if you consider stops on a Raleigh to Panama City flight.

Historically, on average around 9% of flights between Raleigh and Panama City have experienced a delay on any given week. The average delay length over the past 12 months has been 115 minutes.

Generally, flights departing in the early afternoon tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Saturday has historically seen more delays on average compared to the rest of the week.

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 9% of their flights experiencing any sort of delay.

Miami (MIA) was the most common stop: 43% of momondo users choosing 1-stop flights on this route connected there.

Flights via Newark (EWR) offer the lowest average round-trip price of $476.

Flights connecting via Miami (MIA) have the shortest average one-way travel time: 7h 19m.

Miami (MIA) has the shortest average layover time for this route: 1h 54m.

1 flights are operational daily from Raleigh to Panama City as of April 2026. The most popular departure time for this route is 4:00PM, with 100% of flights per day taking off in the afternoon.

8 flights are operational weekly from Raleigh to Panama City as of April 2026. The most popular departure day for this route is Mon, with 25% of flights per week taking off on this day.