Cheap flights from Raleigh to Panama City from $344

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Raleigh to Panama City departing on 12/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Multiple Airlines Logo
9:48 pm - 8:06 amRDU-PTY
10h 18m1 stop
Multiple Airlines Logo
10:25 am - 8:30 pmPTY-RDU
10h 05m1 stop
$425Multiple Airlines
Find Deal
Sun, Feb 15 - Thu, Feb 26
Copa Airlines Logo
3:12 pm - 7:46 pmRDU-PTY
4h 34mnonstop
Copa Airlines Logo
8:57 am - 1:14 pmPTY-RDU
4h 17mnonstop
$441Copa Airlines
Find Deal
Sun, Feb 1 - Sun, Feb 8
United Airlines Logo
6:30 am - 2:45 pmRDU-PTY
8h 15m1 stop
United Airlines Logo
4:41 pm - 12:12 pmPTY-RDU
19h 31m1 stop
$447United Airlines
Find Deal
Sat, Feb 14 - Mon, Mar 2
Multiple Airlines Logo
10:53 am - 7:20 pmRDU-PTY
8h 27m1 stop
Multiple Airlines Logo
9:33 pm - 4:28 pmPTY-RDU
18h 55m2 stops
$449Multiple Airlines
Find Deal
Sun, Feb 1 - Sun, Feb 8
Multiple Airlines Logo
6:10 am - 7:20 pmRDU-PTY
13h 10m2 stops
Multiple Airlines Logo
10:25 am - 8:30 pmPTY-RDU
10h 05m1 stop
$455Multiple Airlines
Find Deal
Mon, Jan 19 - Thu, Feb 26
United Airlines Logo
6:15 am - 7:38 pmRDU-PTY
13h 23m2 stops
United Airlines Logo
11:35 am - 10:43 pmPTY-RDU
11h 08m1 stop
$456United Airlines
Find Deal
Sun, Feb 1 - Sun, Feb 8
Multiple Airlines Logo
6:10 am - 4:06 pmRDU-PTY
9h 56m2 stops
Multiple Airlines Logo
12:33 pm - 8:30 pmPTY-RDU
7h 57m1 stop
$459Multiple Airlines
Find Deal
Thu, Feb 12 - Thu, Feb 26
American Airlines Logo
5:40 pm - 1:27 pmRDU-PTY
19h 47m2 stops
American Airlines Logo
2:52 pm - 11:56 amPTY-RDU
21h 04m2 stops
$460American Airlines
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Wed, Feb 4 - Wed, Feb 18
American Airlines Logo
7:30 am - 3:38 pmRDU-PTY
8h 08m1 stop
American Airlines Logo
4:50 pm - 12:17 pmPTY-RDU
19h 27m2 stops
$465American Airlines
Find Deal
Fri, Jan 30 - Sun, Feb 8
American Airlines Logo
7:15 pm - 1:27 pmRDU-PTY
18h 12m1 stop
American Airlines Logo
4:50 pm - 11:01 amPTY-RDU
18h 11m1 stop
$467American Airlines
Find Deal
Sun, Jan 18 - Fri, Jan 23

Delta flights from Raleigh to Panama City

Our best Delta deals on Raleigh to Panama City flight tickets
Delta
Apr 29
RDU6:35 amRaleigh-Durham
7h 20m
1 stop
PTY12:55 pmPanama City Tocumen Intl
May 5
PTY2:20 pmPanama City Tocumen Intl
9h 06m
1 stop
RDU12:26 amRaleigh-Durham
Delta
Apr 29
RDU5:20 amRaleigh-Durham
8h 35m
1 stop
PTY12:55 pmPanama City Tocumen Intl
May 5
PTY2:20 pmPanama City Tocumen Intl
9h 06m
1 stop
RDU12:26 amRaleigh-Durham
Delta
Apr 26
RDU7:58 pmRaleigh-Durham
17h 57m
1 stop
PTY12:55 pmPanama City Tocumen Intl
May 9
PTY2:20 pmPanama City Tocumen Intl
9h 06m
1 stop
RDU12:26 amRaleigh-Durham

Copa Airlines flights from Raleigh to Panama City

Our best Copa Airlines deals on Raleigh to Panama City flight tickets
Copa Airlines
Apr 29
RDU4:09 pmRaleigh-Durham
4h 37m
PTY7:46 pmPanama City Tocumen Intl
May 6
PTY8:57 amPanama City Tocumen Intl
4h 18m
RDU2:15 pmRaleigh-Durham
Copa Airlines
Mar 1
RDU3:14 pmRaleigh-Durham
4h 32m
PTY7:46 pmPanama City Tocumen Intl
Mar 15
PTY8:57 amPanama City Tocumen Intl
4h 26m
RDU2:23 pmRaleigh-Durham
Copa Airlines
Dec 1
RDU3:11 pmRaleigh-Durham
4h 35m
PTY7:46 pmPanama City Tocumen Intl
Dec 19
PTY8:57 amPanama City Tocumen Intl
4h 28m
RDU1:25 pmRaleigh-Durham

momondo Fare Finder

 
Customize your flight search to find flights from Raleigh to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 18, 2025.
Use the filters below to find and compare flights from Raleigh to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 2/15

9:48 pm-8:06 am

1 stop10h 18m

Panama City Tocumen Intl

Thu 2/26

10:25 am-8:30 pm

1 stop10h 05m

$425

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 2/1

3:12 pm-7:46 pm

Nonstop4h 34m

Panama City Tocumen Intl

Sun 2/8

8:57 am-1:14 pm

Nonstop4h 17m

$441

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sat 2/14

6:30 am-2:45 pm

1 stop8h 15m

Panama City Tocumen Intl

Mon 3/2

4:41 pm-12:12 pm

1 stop19h 31m

$447

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 2/1

10:53 am-7:20 pm

1 stop8h 27m

Panama City Tocumen Intl

Sun 2/8

9:33 pm-4:28 pm

2 stops18h 55m

$449

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 1/19

6:10 am-7:20 pm

2 stops13h 10m

Panama City Tocumen Intl

Thu 2/26

10:25 am-8:30 pm

1 stop10h 05m

$455

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 2/1

6:15 am-7:38 pm

2 stops13h 23m

Panama City Tocumen Intl

Sun 2/8

11:35 am-10:43 pm

1 stop11h 08m

$456

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Thu 2/12

6:10 am-4:06 pm

2 stops9h 56m

Panama City Tocumen Intl

Thu 2/26

12:33 pm-8:30 pm

1 stop7h 57m

$459

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Wed 2/4

5:40 pm-1:27 pm

2 stops19h 47m

Panama City Tocumen Intl

Wed 2/18

2:52 pm-11:56 am

2 stops21h 04m

$460

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 1/30

7:30 am-3:38 pm

1 stop8h 08m

Panama City Tocumen Intl

Sun 2/8

4:50 pm-12:17 pm

2 stops19h 27m

$465

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 1/18

7:15 pm-1:27 pm

1 stop18h 12m

Panama City Tocumen Intl

Fri 1/23

4:50 pm-11:01 am

1 stop18h 11m

$467

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Raleigh to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, October is the cheapest month to fly from Raleigh to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $402. If you’re not able to fly to Panama City in October, then September is your next best option. Flight prices from Raleigh to Panama City during September average around $418.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $317. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $856. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is at noon. Flights from Raleigh to Panama City during this time can be as low as $413. Try not to purchase tickets in the morning because they tend to be around $553. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Raleigh-Durham to Panama City Tocumen Intl flight route?

Fly from Raleigh-Durham to Panama City Tocumen Intl for the best Raleigh-Durham - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Raleigh when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $491 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Raleigh for as low as $406 on momondo.

What cabin class options are available on Raleigh-Durham to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Raleigh-Durham to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Raleigh to Panama City flights?

You could potentially save up to 73% on your flight if you consider stops on a Raleigh to Panama City flight.

How have Raleigh to Panama City flight prices changed over time?

As of November 2025, prices for Raleigh to Panama City flights are approximately 101% more expensive when compared to flights at the same time last year.

When to book flights from Raleigh to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Raleigh to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Raleigh to Panama City (RDU to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Raleigh to Panama City

Best Price Found

$200

Fastest flight time

4h 32m

Direct flights

Mon, Tue, Thu, Fri, Sat and Sun

Airports in Panama City

1 airport
The best one-way flight to Panama City from Raleigh in the past 72 hours is $200. The best round-trip flight deal from Raleigh to Panama City found on momondo in the last 72 hours is $356.
The fastest flight from Raleigh to Panama City takes 4h 32m
Direct flights go from Raleigh to Panama City on Monday, Tuesday, Thursday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
  • How far is Raleigh-Durham to Panama City Tocumen Intl by plane?

    Raleigh-Durham and Panama City Tocumen Intl are 1850.6 mi apart from one another. In terms of flight time, this usually takes a little over 4h 32m.

  • When did momondo last update prices for flights from Raleigh-Durham Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Raleigh-Durham Airport to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from Raleigh-Durham Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Raleigh-Durham Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Raleigh-Durham Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Raleigh to Panama City?

  • What is the most popular airline from Raleigh to Panama City?

Best airlines flying from Raleigh to Panama City

Compare and see reviews for airlines that fly from Raleigh to Panama City with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $249Free CancellationRating
7.2
11,048 reviews
Search American Airlines flights
Copa AirlinesPriceFrom $318Free CancellationRating
7.6
1,566 reviews
Search Copa Airlines flights
DeltaPriceFrom $367Free CancellationRating
7.9
8,007 reviews
Search Delta flights
United AirlinesPriceFrom $409Free CancellationRating
7.4
9,016 reviews
Search United Airlines flights
  • Copa Airlines Flights From Raleigh to Panama City

    Copa Airlines flies from Raleigh to Panama City around 5 times per week, with 1,566 momondo users rating the airline 7.6/10. The cheapest Copa Airlines deal from Raleigh to Panama City in the last 72 hours was $318 (round-trip), much lower than the average airfare cost of $460 for Copa Airlines flights on this route.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Raleigh to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Raleigh to Panama City for you.

Can I find flights from Raleigh to Panama City with flexible booking policies on momondo?

All flight searches from Raleigh to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Raleigh to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Raleigh.

I’m not ready to book a flight from Raleigh to Panama City right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Raleigh to Panama City flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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1 adult
Thu 12/18
Thu 12/25

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