Cheap flights from Panama City to Medellín from $203

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Cheap round-trip flights

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Avianca Logo
6:10 pm - 11:40 pmPTY  Panama City Tocumen Intl-MDE Medellín Jose Maria Cordova Intl
5h 30m1 stop Bogotá El Dorado
Avianca Logo
10:20 am - 3:15 pmMDE  Medellín Jose Maria Cordova Intl-PTY Panama City Tocumen Intl
4h 55m1 stop Bogotá El Dorado
$324Avianca
Wed, Jan 27 - Mon, Feb 8
Avianca Logo
6:10 pm - 10:55 pmPTY  Panama City Tocumen Intl-MDE Medellín Jose Maria Cordova Intl
4h 45m1 stop Bogotá El Dorado
Avianca Logo
10:45 am - 5:15 pmMDE  Medellín Jose Maria Cordova Intl-PTY Panama City Tocumen Intl
6h 30m1 stop Bogotá El Dorado
$324Avianca
Mon, Feb 15 - Wed, Feb 17
Avianca Logo
6:10 pm - 10:55 pmPTY  Panama City Tocumen Intl-MDE Medellín Jose Maria Cordova Intl
4h 45m1 stop Bogotá El Dorado
Avianca Logo
10:45 am - 5:15 pmMDE  Medellín Jose Maria Cordova Intl-PTY Panama City Tocumen Intl
6h 30m1 stop Bogotá El Dorado
$324Avianca
Wed, Feb 10 - Fri, Feb 12
Avianca Logo
4:10 pm - 9:30 pmPTY  Panama City Tocumen Intl-MDE Medellín Jose Maria Cordova Intl
5h 20m1 stop Bogotá El Dorado
Avianca Logo
7:40 am - 2:15 pmMDE  Medellín Jose Maria Cordova Intl-PTY Panama City Tocumen Intl
6h 35m1 stop Bogotá El Dorado
$324Avianca
Mon, Mar 22 - Sat, Apr 3
Copa Airlines Logo
9:32 am - 10:55 amPTY  Panama City Tocumen Intl-MDE Medellín Jose Maria Cordova Intl
1h 23mnonstop
Copa Airlines Logo
12:40 pm - 2:10 pmMDE  Medellín Jose Maria Cordova Intl-PTY Panama City Tocumen Intl
1h 30mnonstop
$353Copa Airlines
Mon, Jan 11 - Tue, Jan 12
Copa Airlines Logo
6:56 am - 8:15 amPTY  Panama City Tocumen Intl-MDE Medellín Jose Maria Cordova Intl
1h 19mnonstop
Copa Airlines Logo
6:25 am - 7:53 amMDE  Medellín Jose Maria Cordova Intl-PTY Panama City Tocumen Intl
1h 28mnonstop
$353Copa Airlines
Sat, Feb 13 - Sun, Feb 14
Copa Airlines Logo
12:57 pm - 2:15 pmPTY  Panama City Tocumen Intl-MDE Medellín Jose Maria Cordova Intl
1h 18mnonstop
Copa Airlines Logo
12:40 pm - 2:11 pmMDE  Medellín Jose Maria Cordova Intl-PTY Panama City Tocumen Intl
1h 31mnonstop
$353Copa Airlines
Thu, Dec 3 - Fri, Dec 4
Multiple Airlines Logo
4:10 pm - 8:44 amPTY  Panama City Tocumen Intl-MDE Medellín Jose Maria Cordova Intl
16h 34m2 stops Bogotá El Dorado Santa Marta Simon Bolivar
Multiple Airlines Logo
12:00 pm - 3:15 pmMDE  Medellín Jose Maria Cordova Intl-PTY Panama City Tocumen Intl
27h 15m2 stops Santa Marta Simon Bolivar Bogotá El Dorado
$447Multiple Airlines
Fri, Dec 4 - Sun, Dec 6
Multiple Airlines Logo
4:10 pm - 8:44 amPTY  Panama City Tocumen Intl-MDE Medellín Jose Maria Cordova Intl
16h 34m2 stops Bogotá El Dorado Santa Marta Simon Bolivar
Multiple Airlines Logo
2:30 pm - 3:15 pmMDE  Medellín Jose Maria Cordova Intl-PTY Panama City Tocumen Intl
24h 45m2 stops Santa Marta Simon Bolivar Bogotá El Dorado
$450Multiple Airlines
Fri, Dec 4 - Sun, Dec 6
Multiple Airlines Logo
10:05 am - 8:44 amPTY  Panama City Tocumen Intl-MDE Medellín Jose Maria Cordova Intl
22h 39m2 stops Bogotá El Dorado Santa Marta Simon Bolivar
Multiple Airlines Logo
6:05 pm - 3:15 pmMDE  Medellín Jose Maria Cordova Intl-PTY Panama City Tocumen Intl
21h 10m2 stops Santa Marta Simon Bolivar Bogotá El Dorado
$451Multiple Airlines
Fri, Dec 4 - Sat, Dec 5

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Avianca flights from Panama City to Medellín Jose Maria Cordova Intl Airport

Our best Avianca deals on Panama City to Medellín Jose Maria Cordova Intl Airport flight tickets
Avianca
Nov 15
PTY10:05 amPanama City Tocumen Intl
6h 45m
1 stop
MDE4:50 pmMedellín Jose Maria Cordova Intl
Nov 17
MDE12:15 pmMedellín Jose Maria Cordova Intl
5h 00m
1 stop
PTY5:15 pmPanama City Tocumen Intl
$324
Avianca
Nov 20
PTY10:05 amPanama City Tocumen Intl
6h 45m
1 stop
MDE4:50 pmMedellín Jose Maria Cordova Intl
Nov 25
MDE10:20 amMedellín Jose Maria Cordova Intl
4h 55m
1 stop
PTY3:15 pmPanama City Tocumen Intl
$325
Avianca
Jan 3
PTY2:30 amPanama City Tocumen Intl
5h 30m
1 stop
MDE8:00 amMedellín Jose Maria Cordova Intl
Jan 10
MDE8:40 pmMedellín Jose Maria Cordova Intl
4h 40m
1 stop
PTY1:20 amPanama City Tocumen Intl
$326

Copa Airlines flights from Panama City to Medellín Jose Maria Cordova Intl Airport

Our best Copa Airlines deals on Panama City to Medellín Jose Maria Cordova Intl Airport flight tickets
Copa Airlines
Nov 21
PTY9:34 amPanama City Tocumen Intl
1h 21m
MDE10:55 amMedellín Jose Maria Cordova Intl
Nov 22
MDE9:15 amMedellín Jose Maria Cordova Intl
1h 30m
PTY10:45 amPanama City Tocumen Intl
$353
Copa Airlines
Nov 19
PTY6:57 amPanama City Tocumen Intl
1h 18m
MDE8:15 amMedellín Jose Maria Cordova Intl
Nov 23
MDE10:45 amMedellín Jose Maria Cordova Intl
1h 29m
PTY12:14 pmPanama City Tocumen Intl
$354
Copa Airlines
Dec 24
PTY6:53 amPanama City Tocumen Intl
1h 22m
MDE8:15 amMedellín Jose Maria Cordova Intl
Dec 27
MDE6:20 pmMedellín Jose Maria Cordova Intl
1h 34m
PTY7:54 pmPanama City Tocumen Intl
$365

momondo Fare Finder

 
Use the filters below to find and compare flights from Panama City to Medellín Jose Maria Cordova Intl Airport that are best for you.

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Route

Depart

Return

Price

Cheapest round-trip

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Wed 1/27

6:10 pm-11:40 pm

1 stop5h 30m

Medellín Jose Maria Cordova Intl

Mon 2/8

10:20 am-3:15 pm

1 stop4h 55m

$324

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Mon 2/15

6:10 pm-10:55 pm

1 stop4h 45m

Medellín Jose Maria Cordova Intl

Wed 2/17

10:45 am-5:15 pm

1 stop6h 30m

$324

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Wed 2/10

6:10 pm-10:55 pm

1 stop4h 45m

Medellín Jose Maria Cordova Intl

Fri 2/12

10:45 am-5:15 pm

1 stop6h 30m

$324

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Mon 3/22

4:10 pm-9:30 pm

1 stop5h 20m

Medellín Jose Maria Cordova Intl

Sat 4/3

7:40 am-2:15 pm

1 stop6h 35m

$324

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Mon 1/11

9:32 am-10:55 am

Nonstop1h 23m

Medellín Jose Maria Cordova Intl

Tue 1/12

12:40 pm-2:10 pm

Nonstop1h 30m

$353
Quickest round-trip

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Sat 2/13

6:56 am-8:15 am

Nonstop1h 19m

Medellín Jose Maria Cordova Intl

Sun 2/14

6:25 am-7:53 am

Nonstop1h 28m

$353

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Thu 12/3

12:57 pm-2:15 pm

Nonstop1h 18m

Medellín Jose Maria Cordova Intl

Fri 12/4

12:40 pm-2:11 pm

Nonstop1h 31m

$353

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Fri 12/4

4:10 pm-8:44 am

2 stops16h 34m

Medellín Jose Maria Cordova Intl

Sun 12/6

12:00 pm-3:15 pm

2 stops27h 15m

$447

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Fri 12/4

4:10 pm-8:44 am

2 stops16h 34m

Medellín Jose Maria Cordova Intl

Sun 12/6

2:30 pm-3:15 pm

2 stops24h 45m

$450

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Fri 12/4

10:05 am-8:44 am

2 stops22h 39m

Medellín Jose Maria Cordova Intl

Sat 12/5

6:05 pm-3:15 pm

2 stops21h 10m

$451

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Medellín from

How to get the cheapest flight ticket from Panama City to Medellín Jose Maria Cordova Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Medellín Jose Maria Cordova Intl Airport?

Prices are currently high for flights on this route.

Typical prices usually range from $152 to $278.
The lowest price recently found on this route was $324.

What is the cheapest month to fly to Medellín Jose Maria Cordova Intl Airport?

In general, March is the cheapest month to fly from Panama City to Medellín Jose Maria Cordova Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $166. If you aren’t able to travel during the month of March, then book flights to Medellín Jose Maria Cordova Intl Airport from Panama City during May instead. Flights to Medellín Jose Maria Cordova Intl Airport in May, while not as cheap as those in March, still average around $179.

What is the cheapest day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

The cheapest day to depart from Panama City to Medellín Jose Maria Cordova Intl Airport is on a Tuesday. Travelers who choose to depart for Medellín Jose Maria Cordova Intl Airport on a Tuesday will often find tickets for as low as $276. On the other hand, Sunday is the most expensive day to depart from Panama City because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $313.

What is the cheapest time of day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

Our data shows that the cheapest Panama City to Medellín Jose Maria Cordova Intl Airport flights are usually those with departure times in the morning. Our users have found flights to Medellín Jose Maria Cordova Intl Airport in the morning for as low as $283. In contrast, the most expensive time of day to depart to Medellín Jose Maria Cordova Intl Airport is in the afternoon when prices are around $320.

What is the cheapest Panama City Tocumen Intl to Medellín Jose Maria Cordova Intl flight route?

Fly from Panama City Tocumen Intl to Medellín Jose Maria Cordova Intl for the best Panama City Tocumen Intl - Medellín Jose Maria Cordova Intl flight prices

How far in advance should I book a flight from Panama City to Medellín Jose Maria Cordova Intl Airport?

You are more likely to see cheaper flights to Medellín Jose Maria Cordova Intl Airport from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Medellín Jose Maria Cordova Intl Airport for around $212 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Medellín Jose Maria Cordova Intl Airport from Panama City for as low as $177 on momondo.

What cabin class options are available on Panama City to Medellín Jose Maria Cordova Intl Airport flights?

There are 2 cabin classes available to choose from on Panama City to Medellín Jose Maria Cordova Intl Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Medellín Jose Maria Cordova Intl Airport flights?

You could potentially save up to 2% on your flight if you consider stops on a Panama City to Medellín Jose Maria Cordova Intl Airport flight.

How have Panama City to Medellín Jose Maria Cordova Intl Airport flight prices changed over time?

As of November 2026, prices for Panama City to Medellín Jose Maria Cordova Intl Airport flights are approximately 2% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Medellín Jose Maria Cordova Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Medellín Jose Maria Cordova Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Medellín Jose Maria Cordova Intl Airport (PTY to MDE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Medellín Jose Maria Cordova Intl Airport

Best Price Found

$203

Fastest flight time

1h 17m

Direct flights

Every day
The best one-way flight to Medellín Jose Maria Cordova Intl Airport from Panama City in the past 72 hours is $203. The best round-trip flight deal from Panama City to Medellín Jose Maria Cordova Intl Airport found on momondo in the last 72 hours is $324.
The fastest flight from Panama City to Medellín Jose Maria Cordova Intl Airport takes 1h 17m
Direct flights go from Panama City to Medellín Jose Maria Cordova Intl Airport every day.

Frequently asked questions about flying from Panama City to Medellín Jose Maria Cordova Intl Airport

  • How far is Panama City Tocumen Intl to Medellín Jose Maria Cordova Intl by plane?

    Medellín Jose Maria Cordova Intl is 341.6 mi away from Panama City Tocumen Intl. Flights usually cover this in 1h 17m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Medellín Jose Maria Cordova Intl Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Medellín Jose Maria Cordova Intl Airport were last updated today.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Medellín Jose Maria Cordova Intl Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Medellín Jose Maria Cordova Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Medellín Jose Maria Cordova Intl Airport.

  • What documentation or ID do you need to fly to Medellín Jose Maria Cordova Intl Airport?

    The necessary travel and health documents for your Medellín Jose Maria Cordova Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama City to Medellín Jose Maria Cordova Intl Airport?

  • What is the most popular airline from Panama City to Medellín Jose Maria Cordova Intl Airport?

Best airlines flying from Panama City to Medellín Jose Maria Cordova Intl Airport

Compare and see reviews for airlines that fly from Panama City to Medellín Jose Maria Cordova Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
WingoPriceFrom $72Free CancellationRating
0.0
0 reviews
Search Wingo flights
Copa AirlinesPriceFrom $140Free CancellationRating
7.6
1,554 reviews
Search Copa Airlines flights
AviancaPriceFrom $151Free CancellationRating
6.5
2,549 reviews
Search Avianca flights
  • Copa Airlines Flights From Panama City to Medellín Jose Maria Cordova Intl Airport

    Copa Airlines operates around 40 flights from Panama City to Medellín Jose Maria Cordova Intl Airport every week. The average price of these flights found in the last 72 hours has been $285, but momondo users have found Copa Airlines deals from Panama City to Medellín Jose Maria Cordova Intl Airport from as low as $140 round-trip. Copa Airlines has been scored 7.6/10 in 1,554 reviews.

Traveling to a place near Medellín?

Book flights to Medellín if you plan to visit one of these locations
Guatapé
Rionegro

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Medellín?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Medellín. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Medellín with flexible booking policies on momondo?

Flights from Panama City to Medellín with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to Medellín?

Once all potential Panama City to Medellín flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama City to Medellín right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Medellín flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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1 adult
Sat 12/12
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