Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Panama City to Medellín from $150

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Medellín departing on 10/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Panama City to Medellín

Cheap round-trip flights

Avianca Logo
11:20 am - 12:30 pmPTY-MDE
1h 10mnonstop
Avianca Logo
5:49 pm - 12:10 amMDE-PTY
6h 21m1 stop
$240Avianca
Find Deal
Wed, Sep 17 - Sat, Sep 20
Avianca Logo
11:20 am - 12:30 pmPTY-MDE
1h 10mnonstop
Avianca Logo
4:56 am - 9:40 amMDE-PTY
4h 44m1 stop
$243Avianca
Find Deal
Sun, Nov 2 - Tue, Nov 4
Avianca Logo
11:20 am - 12:30 pmPTY-MDE
1h 10mnonstop
Avianca Logo
4:56 am - 9:40 amMDE-PTY
4h 44m1 stop
$244Avianca
Find Deal
Sun, Nov 2 - Tue, Nov 4
Copa Airlines Logo
6:54 am - 8:17 amPTY-MDE
1h 23mnonstop
Copa Airlines Logo
4:20 pm - 5:47 pmMDE-PTY
1h 27mnonstop
$260Copa Airlines
Find Deal
Sat, Aug 23 - Tue, Aug 26
Avianca Logo
3:19 am - 7:41 amPTY-MDE
4h 22m1 stop
Avianca Logo
6:00 pm - 7:15 pmMDE-PTY
1h 15mnonstop
$272Avianca
Find Deal
Wed, Oct 29 - Sun, Nov 2
Copa Airlines Logo
9:32 am - 10:56 amPTY-MDE
1h 24mnonstop
Copa Airlines Logo
9:17 am - 10:45 amMDE-PTY
1h 28mnonstop
$284Copa Airlines
Find Deal
Sat, Nov 15 - Sat, Nov 22
Logo
3:20 am - 11:50 amPTY-MDE
8h 30m1 stop
Logo
10:09 am - 4:30 pmMDE-PTY
6h 21m1 stop
$290
Find Deal
Sat, Aug 23 - Sun, Aug 31
Avianca Logo
11:20 am - 12:30 pmPTY-MDE
1h 10mnonstop
Avianca Logo
4:59 am - 12:35 pmMDE-PTY
7h 36m1 stop
$295Avianca
Find Deal
Tue, Aug 12 - Wed, Aug 13
Copa Airlines Logo
6:54 am - 8:17 amPTY-MDE
1h 23mnonstop
Copa Airlines Logo
6:21 pm - 7:47 pmMDE-PTY
1h 26mnonstop
$301Copa Airlines
Find Deal
Fri, Aug 15 - Sun, Aug 17
Copa Airlines Logo
7:32 am - 8:55 amPTY-MDE
1h 23mnonstop
Copa Airlines Logo
10:46 am - 12:15 pmMDE-PTY
1h 29mnonstop
$302Copa Airlines
Find Deal
Tue, Aug 12 - Fri, Aug 15

Copa Airlines flights from Panama City to Medellín Jose Maria Cordova Intl Airport

Our best Copa Airlines deals on Panama City to Medellín Jose Maria Cordova Intl Airport flight tickets
Copa Airlines
Aug 23
PTY6:54 amPanama City Tocumen Intl
1h 23m
MDE8:17 amMedellín Jose Maria Cordova Intl
Aug 26
MDE4:20 pmMedellín Jose Maria Cordova Intl
1h 27m
PTY5:47 pmPanama City Tocumen Intl
$260
Find similar
Copa Airlines
Nov 15
PTY9:32 amPanama City Tocumen Intl
1h 24m
MDE10:56 amMedellín Jose Maria Cordova Intl
Nov 22
MDE9:17 amMedellín Jose Maria Cordova Intl
1h 28m
PTY10:45 amPanama City Tocumen Intl
$284
Find similar
Copa Airlines
Aug 15
PTY6:54 amPanama City Tocumen Intl
1h 23m
MDE8:17 amMedellín Jose Maria Cordova Intl
Aug 17
MDE6:21 pmMedellín Jose Maria Cordova Intl
1h 26m
PTY7:47 pmPanama City Tocumen Intl
$301
Find similar

Avianca flights from Panama City to Medellín Jose Maria Cordova Intl Airport

Our best Avianca deals on Panama City to Medellín Jose Maria Cordova Intl Airport flight tickets
Avianca
Sep 17
PTY11:20 amPanama City Tocumen Intl
1h 10m
MDE12:30 pmMedellín Jose Maria Cordova Intl
Sep 20
MDE5:49 pmMedellín Jose Maria Cordova Intl
6h 21m
1 stop
PTY12:10 amPanama City Tocumen Intl
$240
Find similar
Avianca
Nov 2
PTY11:20 amPanama City Tocumen Intl
1h 10m
MDE12:30 pmMedellín Jose Maria Cordova Intl
Nov 4
MDE4:56 amMedellín Jose Maria Cordova Intl
4h 44m
1 stop
PTY9:40 amPanama City Tocumen Intl
$243
Find similar
Avianca
Nov 2
PTY11:20 amPanama City Tocumen Intl
1h 10m
MDE12:30 pmMedellín Jose Maria Cordova Intl
Nov 4
MDE4:56 amMedellín Jose Maria Cordova Intl
4h 44m
1 stop
PTY9:40 amPanama City Tocumen Intl
$244
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Medellín Jose Maria Cordova Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Panama City to Medellín Jose Maria Cordova Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Wed 9/17

11:20 am-12:30 pm

Nonstop1h 10m

Medellín Jose Maria Cordova Intl

Sat 9/20

5:49 pm-12:10 am

1 stop6h 21m

$240

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Sun 11/2

11:20 am-12:30 pm

Nonstop1h 10m

Medellín Jose Maria Cordova Intl

Tue 11/4

4:56 am-9:40 am

1 stop4h 44m

$243

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Sun 11/2

11:20 am-12:30 pm

Nonstop1h 10m

Medellín Jose Maria Cordova Intl

Tue 11/4

4:56 am-9:40 am

1 stop4h 44m

$244

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Sat 8/23

6:54 am-8:17 am

Nonstop1h 23m

Medellín Jose Maria Cordova Intl

Tue 8/26

4:20 pm-5:47 pm

Nonstop1h 27m

$260

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Wed 10/29

3:19 am-7:41 am

1 stop4h 22m

Medellín Jose Maria Cordova Intl

Sun 11/2

6:00 pm-7:15 pm

Nonstop1h 15m

$272

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Sat 11/15

9:32 am-10:56 am

Nonstop1h 24m

Medellín Jose Maria Cordova Intl

Sat 11/22

9:17 am-10:45 am

Nonstop1h 28m

$284

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Sat 8/23

3:20 am-11:50 am

1 stop8h 30m

Medellín Jose Maria Cordova Intl

Sun 8/31

10:09 am-4:30 pm

1 stop6h 21m

$290

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Tue 8/12

11:20 am-12:30 pm

Nonstop1h 10m

Medellín Jose Maria Cordova Intl

Wed 8/13

4:59 am-12:35 pm

1 stop7h 36m

$295

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Fri 8/15

6:54 am-8:17 am

Nonstop1h 23m

Medellín Jose Maria Cordova Intl

Sun 8/17

6:21 pm-7:47 pm

Nonstop1h 26m

$301

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Tue 8/12

7:32 am-8:55 am

Nonstop1h 23m

Medellín Jose Maria Cordova Intl

Fri 8/15

10:46 am-12:15 pm

Nonstop1h 29m

$302

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Medellín from

How to get the cheapest flight ticket from Panama City to Medellín Jose Maria Cordova Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Medellín Jose Maria Cordova Intl Airport?

In general, May is the cheapest month to fly from Panama City to Medellín Jose Maria Cordova Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $151. If you aren’t able to travel during the month of May, then book flights to Medellín Jose Maria Cordova Intl Airport from Panama City during April instead. Flights to Medellín Jose Maria Cordova Intl Airport in April, while not as cheap as those in May, still average around $167.

What is the cheapest day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

The cheapest day to depart from Panama City to Medellín Jose Maria Cordova Intl Airport is on a Tuesday. Travelers who choose to depart for Medellín Jose Maria Cordova Intl Airport on a Tuesday will often find tickets for as low as $249. On the other hand, Sunday is the most expensive day to depart from Panama City because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $260.

What is the cheapest time of day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

Our data shows that the cheapest Panama City to Medellín Jose Maria Cordova Intl Airport flights are usually those with departure times in the evening. Our users have found flights to Medellín Jose Maria Cordova Intl Airport in the evening for as low as $210. In contrast, the most expensive time of day to depart to Medellín Jose Maria Cordova Intl Airport is in the afternoon when prices are around $273.

What is the cheapest Panama City Tocumen Intl to Medellín Jose Maria Cordova Intl flight route?

Fly from Panama City Tocumen Intl to Medellín Jose Maria Cordova Intl for the best Panama City Tocumen Intl - Medellín Jose Maria Cordova Intl flight prices

How far in advance should I book a flight to Medellín Jose Maria Cordova Intl Airport?

You are more likely to see cheaper flights to Medellín Jose Maria Cordova Intl Airport from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Medellín Jose Maria Cordova Intl Airport for around $182 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Medellín Jose Maria Cordova Intl Airport from Panama City for as low as $176 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Medellín Jose Maria Cordova Intl flights?

There are 2 cabin classes available to choose from on Panama City Tocumen Intl to Medellín Jose Maria Cordova Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Panama City to Medellín Jose Maria Cordova Intl Airport flight prices changed over time?

As of July 2025, prices for Panama City to Medellín Jose Maria Cordova Intl Airport flights are approximately 10% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Medellín Jose Maria Cordova Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Medellín Jose Maria Cordova Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Medellín Jose Maria Cordova Intl Airport (PTY to MDE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Medellín Jose Maria Cordova Intl Airport

Best Price Found

$150

Fastest flight time

1h 10m

Direct flights

Every day
The best one-way flight to Medellín Jose Maria Cordova Intl Airport from Panama City in the past 72 hours is $150. The best round-trip flight deal from Panama City to Medellín Jose Maria Cordova Intl Airport found on momondo in the last 72 hours is $240.
The fastest flight from Panama City to Medellín Jose Maria Cordova Intl Airport takes 1h 10m
Direct flights go from Panama City to Medellín Jose Maria Cordova Intl Airport every day.
Search flight deals

  • How far is Panama City Tocumen Intl to Medellín Jose Maria Cordova Intl by plane?

    Medellín Jose Maria Cordova Intl is 341.6 mi away from Panama City Tocumen Intl. Flights usually cover this in 1h 10m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Medellín Jose Maria Cordova Intl Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Medellín Jose Maria Cordova Intl Airport were last updated today.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Medellín Jose Maria Cordova Intl Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Medellín Jose Maria Cordova Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Medellín Jose Maria Cordova Intl Airport.

  • What documentation or ID do you need to fly to Medellín Jose Maria Cordova Intl Airport?

    The necessary travel and health documents for your Medellín Jose Maria Cordova Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama City to Medellín Jose Maria Cordova Intl Airport?

  • What is the most popular airline from Panama City to Medellín Jose Maria Cordova Intl Airport?

Best airlines flying from Panama City to Medellín Jose Maria Cordova Intl Airport

Compare and see reviews for airlines that fly from Panama City to Medellín Jose Maria Cordova Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $119Free CancellationRating
7.5
1,493 reviews
Search Copa Airlines flights
WingoPriceFrom $130Free CancellationRating
7.3
134 reviews
Search Wingo flights
AviancaPriceFrom $173Free CancellationRating
6.7
2,386 reviews
Search Avianca flights

  • Copa Airlines Flights From Panama City to Medellín Jose Maria Cordova Intl Airport

    Copa Airlines operates around 39 flights from Panama City to Medellín Jose Maria Cordova Intl Airport every week. The average price of these flights found in the last 72 hours has been $253, but momondo users have found Copa Airlines deals from Panama City to Medellín Jose Maria Cordova Intl Airport from as low as $119 round-trip. Copa Airlines has been scored 7.5/10 in 1,493 reviews.

  • Avianca Flights From Panama City to Medellín Jose Maria Cordova Intl Airport

    The best Avianca deal for Panama City to Medellín Jose Maria Cordova Intl Airport flight tickets found on momondo in the last 72 hours was $173, round-trip. It should be noted that an average Avianca flight deal for this route in this time was higher, at $214 round-trip. Avianca operates 5 flights out of Panama City into Medellín Jose Maria Cordova Intl Airport in an average week, so prices vary by time and availability. 2,387 Avianca reviews by users on momondo have scored the airline at 6.7/10.

Traveling to a place near Medellín?

Book flights to Medellín if you plan to visit one of these locations
Guatapé
Rionegro

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Medellín?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Medellín. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Medellín with flexible booking policies on momondo?

Flights from Panama City to Medellín with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to Medellín?

Once all potential Panama City to Medellín flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama City to Medellín right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Medellín flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Medellín Jose Maria Cordova Intl Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sun 8/3
Sun 8/10
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Medellín

Popular cities in Colombia

Popular flights according to clicks in the last 7 days on momondo
Flights to Medellín Enrique Olaya Airportfrom $295