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Cheap flights from Panama City to Brussels from $758

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Brussels departing on 7/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama City to Brussels

Cheap round-trip flights

Enter your travel dates to find the best prices.
Turkish Airlines Logo
10:00 pm - 10:35 am
PTY
-
BRU
30h 35m
1 stop
Turkish Airlines Logo
11:35 am - 8:05 pm
BRU
-
PTY
38h 30m
1 stop
$919Turkish Airlines
Wed, Nov 18 - Sun, Nov 22
Air Europa Logo
9:30 pm - 5:45 pm
PTY
-
BRU
14h 15m
1 stop
Air Europa Logo
10:45 am - 7:45 pm
BRU
-
PTY
15h 00m
1 stop
$936Air Europa
Wed, Nov 18 - Sun, Nov 22
Air Europa Logo
9:30 pm - 5:45 pm
PTY
-
BRU
14h 15m
1 stop
Air Europa Logo
10:45 am - 7:45 pm
BRU
-
PTY
15h 00m
1 stop
$937Air Europa
Wed, Nov 18 - Sun, Nov 22
KLM Logo
6:50 pm - 7:35 am
PTY
-
BRU
29h 45m
1 stop
KLM Logo
3:10 pm - 4:50 pm
BRU
-
PTY
32h 40m
1 stop
$941KLM
Sun, Sep 13 - Sun, Sep 27
Turkish Airlines Logo
10:00 pm - 10:10 pm
PTY
-
BRU
18h 10m
1 stop
Turkish Airlines Logo
7:50 am - 5:10 pm
BRU
-
PTY
39h 20m
2 stops
$949Turkish Airlines
Wed, Nov 18 - Sun, Nov 22
KLM Logo
6:50 pm - 7:35 am
PTY
-
BRU
29h 45m
1 stop
KLM Logo
6:20 am - 4:50 pm
BRU
-
PTY
17h 30m
1 stop
$950KLM
Sun, Sep 13 - Mon, Sep 28
KLM Logo
6:50 pm - 7:35 am
PTY
-
BRU
29h 45m
1 stop
KLM Logo
3:10 pm - 4:50 pm
BRU
-
PTY
32h 40m
1 stop
$994KLM
Sun, Sep 13 - Sat, Sep 26
Multiple Airlines Logo
9:05 pm - 10:30 pm
PTY
-
BRU
18h 25m
1 stop
Multiple Airlines Logo
9:05 am - 7:35 pm
BRU
-
PTY
17h 30m
1 stop
$1,005Multiple Airlines
Mon, Sep 14 - Mon, Sep 28
KLM Logo
6:50 pm - 9:40 am
PTY
-
BRU
31h 50m
1 stop
KLM Logo
3:10 pm - 4:50 pm
BRU
-
PTY
32h 40m
1 stop
$1,036KLM
Sat, Sep 12 - Sun, Sep 27
KLM Logo
6:50 pm - 2:40 pm
PTY
-
BRU
12h 50m
1 stop
KLM Logo
8:05 am - 7:45 pm
BRU
-
PTY
18h 40m
2 stops
$1,041KLM
Sun, Sep 13 - Sun, Sep 27

Air Europa flights from Panama City to Brussels Bruxelles-National Airport

Our best Air Europa deals on Panama City to Brussels Bruxelles-National Airport flight tickets
Air Europa
Nov 18
PTY9:30 pmPanama City Tocumen Intl
14h 15m
1 stop
BRU5:45 pmBrussels Bruxelles-National
Nov 22
BRU10:45 amBrussels Bruxelles-National
15h 00m
1 stop
PTY7:45 pmPanama City Tocumen Intl
$936
Air Europa
Nov 18
PTY9:30 pmPanama City Tocumen Intl
14h 15m
1 stop
BRU5:45 pmBrussels Bruxelles-National
Nov 22
BRU10:45 amBrussels Bruxelles-National
15h 00m
1 stop
PTY7:45 pmPanama City Tocumen Intl
$937
Air Europa
Jun 23
PTY8:25 pmPanama City Tocumen Intl
14h 15m
1 stop
BRU5:40 pmBrussels Bruxelles-National
Jun 30
BRU10:45 amBrussels Bruxelles-National
14h 55m
1 stop
PTY6:40 pmPanama City Tocumen Intl
$1,213

Turkish Airlines flights from Panama City to Brussels Bruxelles-National Airport

Our best Turkish Airlines deals on Panama City to Brussels Bruxelles-National Airport flight tickets
Turkish Airlines
Nov 18
PTY10:00 pmPanama City Tocumen Intl
30h 35m
1 stop
BRU10:35 amBrussels Bruxelles-National
Nov 22
BRU11:35 amBrussels Bruxelles-National
38h 30m
1 stop
PTY8:05 pmPanama City Tocumen Intl
$919
Turkish Airlines
Nov 18
PTY10:00 pmPanama City Tocumen Intl
18h 10m
1 stop
BRU10:10 pmBrussels Bruxelles-National
Nov 22
BRU7:50 amBrussels Bruxelles-National
39h 20m
2 stops
PTY5:10 pmPanama City Tocumen Intl
$949
Turkish Airlines
Jul 20
PTY10:20 pmPanama City Tocumen Intl
32h 05m
1 stop
BRU1:25 pmBrussels Bruxelles-National
Aug 3
BRU7:20 amBrussels Bruxelles-National
20h 05m
1 stop
PTY8:25 pmPanama City Tocumen Intl
$1,148

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Brussels Bruxelles-National Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 31, 2026.
Use the filters below to find and compare flights from Panama City to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Wed 11/18

10:00 pm-10:35 am

1 stop30h 35m

Brussels Bruxelles-National

Sun 11/22

11:35 am-8:05 pm

1 stop38h 30m

$919
Quickest round-trip

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Wed 11/18

9:30 pm-5:45 pm

1 stop14h 15m

Brussels Bruxelles-National

Sun 11/22

10:45 am-7:45 pm

1 stop15h 00m

$936

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Wed 11/18

9:30 pm-5:45 pm

1 stop14h 15m

Brussels Bruxelles-National

Sun 11/22

10:45 am-7:45 pm

1 stop15h 00m

$937

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 9/13

6:50 pm-7:35 am

1 stop29h 45m

Brussels Bruxelles-National

Sun 9/27

3:10 pm-4:50 pm

1 stop32h 40m

$941

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Wed 11/18

10:00 pm-10:10 pm

1 stop18h 10m

Brussels Bruxelles-National

Sun 11/22

7:50 am-5:10 pm

2 stops39h 20m

$949

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 9/13

6:50 pm-7:35 am

1 stop29h 45m

Brussels Bruxelles-National

Mon 9/28

6:20 am-4:50 pm

1 stop17h 30m

$950

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 9/13

6:50 pm-7:35 am

1 stop29h 45m

Brussels Bruxelles-National

Sat 9/26

3:10 pm-4:50 pm

1 stop32h 40m

$994

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 9/14

9:05 pm-10:30 pm

1 stop18h 25m

Brussels Bruxelles-National

Mon 9/28

9:05 am-7:35 pm

1 stop17h 30m

$1,005

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 9/12

6:50 pm-9:40 am

1 stop31h 50m

Brussels Bruxelles-National

Sun 9/27

3:10 pm-4:50 pm

1 stop32h 40m

$1,036

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 9/13

6:50 pm-2:40 pm

1 stop12h 50m

Brussels Bruxelles-National

Sun 9/27

8:05 am-7:45 pm

2 stops18h 40m

$1,041

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 11 resultsSorted by cheapest first
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See travel insights to Brussels from

How to get the cheapest flight ticket from Panama City to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Brussels Bruxelles-National Airport?

What is the cheapest month to fly to Brussels Bruxelles-National Airport?

The cheapest month to fly to Brussels Bruxelles-National Airport from Panama City is in February. Flight prices, which tend to average around $809, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of February, then book flights to Brussels Bruxelles-National Airport from Panama City during September instead. Flights to Brussels Bruxelles-National Airport in September, while not as cheap as those in February, still average around $834.

How far in advance should I book a flight from Panama City to Brussels Bruxelles-National Airport?

You are more likely to see cheaper flights to Brussels Bruxelles-National Airport from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Brussels Bruxelles-National Airport for around $970 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Brussels Bruxelles-National Airport from Panama City for as low as $710 on momondo.

How have Panama City to Brussels Bruxelles-National Airport flight prices changed over time?

As of May 2026, prices for Panama City to Brussels Bruxelles-National Airport flights are approximately 33% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Brussels Bruxelles-National Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Brussels Bruxelles-National Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Brussels Bruxelles-National Airport (PTY to BRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Brussels Bruxelles-National Airport

Fastest flight time

40h 05m

Direct flights

None
The fastest flight from Panama City to Brussels Bruxelles-National Airport takes 40h 05m
There are no direct flights from Panama City to Brussels Bruxelles-National Airport. There are no popular flight routes from Panama City to Brussels Bruxelles-National Airport.
Search flight deals

Frequently asked questions about flying from Panama City to Brussels Bruxelles-National Airport

  • How far is Panama City Tocumen Intl to Brussels Bruxelles-National by plane?

    The distance between Panama City Tocumen Intl and Brussels Bruxelles-National is about 5473.2 mi. 40h 05m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport.

  • What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

    The required travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Brussels Bruxelles-National Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Brussels Bruxelles-National Airport?

Best airlines flying from Panama City to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from Panama City to Brussels Bruxelles-National Airport with momondo
Airline
Rating
Free Cancellation
Price
Air FrancePriceFrom $789Free CancellationRating
7.4
1,596 reviews
Search Air France flights
Air EuropaPriceFrom $797Free CancellationRating
7.0
614 reviews
Search Air Europa flights

Traveling to a place near Brussels?

Book flights to Brussels if you plan to visit one of these locations
Bruges
Ghent
Leuven
Charleroi
Zaventem
Mons
Hasselt
Durbuy
Genk
Dinant
Namur
Waterloo
Aalst
Mechelen
Knokke-Heist
Spa
Francorchamps
Tournai
Oostkamp
Halle

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Brussels?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Brussels. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Brussels with flexible booking policies on momondo?

Yes. All flights to Brussels from Panama City on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama City to Brussels?

Once you have performed a search for Panama City to Brussels flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Brussels right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Brussels flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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