What is the cheapest airline that flies from Panama City Tocumen Intl to Brussels Bruxelles-National?

Iberia, Air Europa, and KLM are the most popular carriers operating from Panama City Tocumen Intl to Brussels Bruxelles-National

What day of the week experiences the fewest flight delays on this route?

Wednesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Wednesday has historically seen more delays on average compared to the rest of the week.

Which layover airport has the shortest travel time from Panama City to Brussels Bruxelles-National Airport?

Flights connecting via Amsterdam (AMS) have the shortest average one-way travel time: 12h 50m.

How often are flights from Panama City to Brussels delayed?

Historically, on average around 0% of flights between Panama City and Brussels have experienced a delay on any given week. The average delay length over the past 12 months has been 0 minutes.

Which airport is the most popular layover for flights between Panama City and Brussels Bruxelles-National Airport?

Amsterdam (AMS) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest connection time from Panama City to Brussels Bruxelles-National Airport?

Amsterdam (AMS) has the shortest average layover time for this route: 1h 40m.

What is the most punctual flight time for Panama City to Brussels flights?

Generally, flights departing at night tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

Which layover airport offers the lowest fares from Panama City to Brussels Bruxelles-National Airport?

Flights via Madrid (MAD) offer the lowest average round-trip price of $734.

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

Prices for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport refresh daily.

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

As of August 2026, there is 1 operator available to choose from for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport.

How old do you have to be to fly from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport.

What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

The required travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Brussels Bruxelles-National Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$675 Cheap Flights from Panama City to Brussels Bruxelles-National Airport in 2026

Find the cheapest flights from Panama City to Brussels

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:50 pm - 2:40 pmPTY Panama City Tocumen Intl-BRU Brussels Bruxelles-National

12h 50m1 stop Amsterdam Schiphol

10:25 am - 7:45 pmBRU Brussels Bruxelles-National-PTY Panama City Tocumen Intl

16h 20m2 stops Amsterdam Schiphol Paris Charles de Gaulle

$938KLM

Fri, Oct 16 - Mon, Oct 19

9:55 pm - 10:15 pmPTY Panama City Tocumen Intl-BRU Brussels Bruxelles-National

17h 20m2 stops Paris Charles de Gaulle Amsterdam Schiphol

6:20 am - 4:50 pmBRU Brussels Bruxelles-National-PTY Panama City Tocumen Intl

17h 30m1 stop Amsterdam Schiphol

$944KLM

Sun, Oct 4 - Sun, Oct 11

8:25 pm - 9:45 amPTY Panama City Tocumen Intl-BRU Brussels Bruxelles-National

30h 20m1 stop Madrid Barajas

10:45 am - 6:40 pmBRU Brussels Bruxelles-National-PTY Panama City Tocumen Intl

14h 55m1 stop Madrid Barajas

$945Air Europa

Sun, Oct 4 - Sun, Oct 11

10:20 pm - 3:15 pmPTY Panama City Tocumen Intl-BRU Brussels Bruxelles-National

33h 55m1 stop Istanbul

3:15 pm - 8:05 pmBRU Brussels Bruxelles-National-PTY Panama City Tocumen Intl

34h 50m1 stop Istanbul

$945Turkish Airlines

Fri, Sep 25 - Thu, Dec 10

6:45 pm - 2:15 pmPTY Panama City Tocumen Intl-BRU Brussels Bruxelles-National

13h 30m1 stop Amsterdam Schiphol

10:45 am - 8:20 pmBRU Brussels Bruxelles-National-PTY Panama City Tocumen Intl

15h 35m2 stops Amsterdam Schiphol Paris Charles de Gaulle

$967KLM

Sat, Dec 5 - Wed, Dec 9

10:20 pm - 3:15 pmPTY Panama City Tocumen Intl-BRU Brussels Bruxelles-National

33h 55m1 stop Istanbul

11:35 am - 8:05 pmBRU Brussels Bruxelles-National-PTY Panama City Tocumen Intl

38h 30m1 stop Istanbul

$976Turkish Airlines

Fri, Sep 25 - Thu, Dec 10

10:00 pm - 10:20 pmPTY Panama City Tocumen Intl-BRU Brussels Bruxelles-National

18h 20m1 stop Istanbul

6:30 am - 8:05 pmBRU Brussels Bruxelles-National-PTY Panama City Tocumen Intl

19h 35m1 stop Istanbul

$988Turkish Airlines

Sat, Dec 5 - Wed, Dec 9

8:10 pm - 9:25 pmPTY Panama City Tocumen Intl-BRU Brussels Bruxelles-National

18h 15m1 stop Istanbul

2:25 pm - 8:25 pmBRU Brussels Bruxelles-National-PTY Panama City Tocumen Intl

37h 00m1 stop Istanbul

$1,001Turkish Airlines

Sun, Oct 4 - Sun, Oct 11

9:55 pm - 10:15 pmPTY Panama City Tocumen Intl-BRU Brussels Bruxelles-National

17h 20m2 stops Paris Charles de Gaulle Amsterdam Schiphol

6:20 am - 4:50 pmBRU Brussels Bruxelles-National-PTY Panama City Tocumen Intl

17h 30m1 stop Amsterdam Schiphol

$1,007KLM

Sun, Oct 4 - Sun, Oct 11

9:30 pm - 9:50 amPTY Panama City Tocumen Intl-BRU Brussels Bruxelles-National

30h 20m1 stop Madrid Barajas

6:55 pm - 7:45 pmBRU Brussels Bruxelles-National-PTY Panama City Tocumen Intl

30h 50m1 stop Madrid Barajas

$1,165Air Europa

Sun, Dec 6 - Thu, Dec 10

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

KLM flights from Panama City to Brussels Bruxelles-National Airport

Our best KLM deals on Panama City to Brussels Bruxelles-National Airport flight tickets

KLM

Oct 16

PTY6:50 pmPanama City Tocumen Intl

12h 50m

1 stop

BRU2:40 pmBrussels Bruxelles-National

Oct 19

BRU10:25 amBrussels Bruxelles-National

16h 20m

2 stops

PTY7:45 pmPanama City Tocumen Intl

$938

KLM

Oct 4

PTY9:55 pmPanama City Tocumen Intl

17h 20m

2 stops

BRU10:15 pmBrussels Bruxelles-National

Oct 11

BRU6:20 amBrussels Bruxelles-National

17h 30m

1 stop

PTY4:50 pmPanama City Tocumen Intl

$944

KLM

Dec 5

PTY6:45 pmPanama City Tocumen Intl

13h 30m

1 stop

BRU2:15 pmBrussels Bruxelles-National

Dec 9

BRU10:45 amBrussels Bruxelles-National

15h 35m

2 stops

PTY8:20 pmPanama City Tocumen Intl

$967

Turkish Airlines flights from Panama City to Brussels Bruxelles-National Airport

Our best Turkish Airlines deals on Panama City to Brussels Bruxelles-National Airport flight tickets

Turkish Airlines

Sep 25

PTY10:20 pmPanama City Tocumen Intl

33h 55m

1 stop

BRU3:15 pmBrussels Bruxelles-National

Dec 10

BRU3:15 pmBrussels Bruxelles-National

34h 50m

1 stop

PTY8:05 pmPanama City Tocumen Intl

$945

Turkish Airlines

Sep 25

PTY10:20 pmPanama City Tocumen Intl

33h 55m

1 stop

BRU3:15 pmBrussels Bruxelles-National

Dec 10

BRU11:35 amBrussels Bruxelles-National

38h 30m

1 stop

PTY8:05 pmPanama City Tocumen Intl

$976

Turkish Airlines

Dec 5

PTY10:00 pmPanama City Tocumen Intl

18h 20m

1 stop

BRU10:20 pmBrussels Bruxelles-National

Dec 9

BRU6:30 amBrussels Bruxelles-National

19h 35m

1 stop

PTY8:05 pmPanama City Tocumen Intl

$988

momondo Fare Finder

Use the filters below to find and compare flights from Panama City to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Fri 10/16

6:50 pm-2:40 pm

1 stop12h 50m

Brussels Bruxelles-National

Mon 10/19

10:25 am-7:45 pm

2 stops16h 20m

$938

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Sun 10/4

9:55 pm-10:15 pm

2 stops17h 20m

Brussels Bruxelles-National

Sun 10/11

6:20 am-4:50 pm

1 stop17h 30m

$944

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Sun 10/4

8:25 pm-9:45 am

1 stop30h 20m

Brussels Bruxelles-National

Sun 10/11

10:45 am-6:40 pm

1 stop14h 55m

$945

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Fri 9/25

10:20 pm-3:15 pm

1 stop33h 55m

Brussels Bruxelles-National

Thu 12/10

3:15 pm-8:05 pm

1 stop34h 50m

$945

Quickest round-trip

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Sat 12/5

6:45 pm-2:15 pm

1 stop13h 30m

Brussels Bruxelles-National

Wed 12/9

10:45 am-8:20 pm

2 stops15h 35m

$967

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Fri 9/25

10:20 pm-3:15 pm

1 stop33h 55m

Brussels Bruxelles-National

Thu 12/10

11:35 am-8:05 pm

1 stop38h 30m

$976

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Sat 12/5

10:00 pm-10:20 pm

1 stop18h 20m

Brussels Bruxelles-National

Wed 12/9

6:30 am-8:05 pm

1 stop19h 35m

$988

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Sun 10/4

8:10 pm-9:25 pm

1 stop18h 15m

Brussels Bruxelles-National

Sun 10/11

2:25 pm-8:25 pm

1 stop37h 00m

$1,001

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Sun 10/4

9:55 pm-10:15 pm

2 stops17h 20m

Brussels Bruxelles-National

Sun 10/11

6:20 am-4:50 pm

1 stop17h 30m

$1,007

Panama CityBrussels

PTY Panama City Tocumen Intl - BRU Brussels Bruxelles-National

PTYBRU

Panama City Tocumen Intl

Sun 12/6

9:30 pm-9:50 am

1 stop30h 20m

Brussels Bruxelles-National

Thu 12/10

6:55 pm-7:45 pm

1 stop30h 50m

$1,165

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama City to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Delays

Layovers

What is the typical price of a round-trip flight between Panama City and Brussels Bruxelles-National Airport?

Prices are currently low for flights on this route.

Typical prices usually range from $1,007 to $1,152.
The lowest price recently found on this route was $938.

What is the cheapest month to fly to Brussels Bruxelles-National Airport?

The cheapest month to fly to Brussels Bruxelles-National Airport from Panama City is in March. Flight prices, which tend to average around $804, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of March, then book flights to Brussels Bruxelles-National Airport from Panama City during February instead. Flights to Brussels Bruxelles-National Airport in February, while not as cheap as those in March, still average around $809.

How far in advance should I book a flight from Panama City to Brussels Bruxelles-National Airport?

You are more likely to see cheaper flights to Brussels Bruxelles-National Airport from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Brussels Bruxelles-National Airport for around $995 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Brussels Bruxelles-National Airport from Panama City for as low as $811 on momondo.

How have Panama City to Brussels Bruxelles-National Airport flight prices changed over time?

When to book flights from Panama City to Brussels Bruxelles-National Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Brussels Bruxelles-National Airport according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Panama City to Brussels Bruxelles-National Airport (PTY to BRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Brussels Bruxelles-National Airport

Best Price Found	$675
Fastest flight time	41h 45m
Direct flights	None

The best one-way flight to Brussels Bruxelles-National Airport from Panama City in the past 72 hours is $675. The best round-trip flight deal from Panama City to Brussels Bruxelles-National Airport found on momondo in the last 72 hours is $938.

The fastest flight from Panama City to Brussels Bruxelles-National Airport takes 41h 45m

There are no direct flights from Panama City to Brussels Bruxelles-National Airport. There are no popular flight routes from Panama City to Brussels Bruxelles-National Airport.

Search flight deals

Frequently asked questions about flying from Panama City to Brussels Bruxelles-National Airport

How far is Panama City Tocumen Intl to Brussels Bruxelles-National by plane?
The distance between Panama City Tocumen Intl and Brussels Bruxelles-National is about 5473.2 mi. 41h 45m is a normal flight duration for this route.
When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?
Prices for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport refresh daily.
How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?
As of August 2026, there is 1 operator available to choose from for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport.
How old do you have to be to fly from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport.
What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?
The required travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Brussels Bruxelles-National Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Panama City to Brussels Bruxelles-National Airport?
Based on momondo bookings for flights between Panama City and Brussels Bruxelles-National Airport, the leading airline is Air Europa, making up 100% of the total bookings.

Best airlines flying from Panama City to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from Panama City to Brussels Bruxelles-National Airport with momondo

Airline	Rating	Free Cancellation	Price
Air Europa	PriceFrom $797	Free Cancellation	Rating 7.0 636 reviews		Search Air Europa flights

Bruges

Ghent

Leuven

Dinant

Zaventem

Durbuy

Mons

Charleroi

Genk

Aalst

Waterloo

Mechelen

Namur

Spa

Hasselt

Francorchamps

Knokke-Heist

Halle

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Brussels?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Brussels. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Brussels with flexible booking policies on momondo?

Yes. All flights to Brussels from Panama City on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama City to Brussels?

Once you have performed a search for Panama City to Brussels flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Brussels right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Brussels flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Brussels Bruxelles-National Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Thu 9/24

Thu 10/1

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Brussels

Popular cities

Other flights from Panama City

Other flights to Brussels

Airlines

Cabin classes

Complete your trip

Feeling lucky

Popular cities in Belgium

Flights to Charleroi Brussels Airportfrom $584

Cheap flights from Panama City to Brussels from $675

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Brussels departing on 11/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Find the cheapest flights from Panama City to Brussels

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

KLM flights from Panama City to Brussels Bruxelles-National Airport

Our best KLM deals on Panama City to Brussels Bruxelles-National Airport flight tickets

Turkish Airlines flights from Panama City to Brussels Bruxelles-National Airport

Our best Turkish Airlines deals on Panama City to Brussels Bruxelles-National Airport flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Panama City to Brussels Bruxelles-National Airport that are best for you.

See travel insights to Brussels from

How to get the cheapest flight ticket from Panama City to Brussels Bruxelles-National Airport

What is the typical price of a round-trip flight between Panama City and Brussels Bruxelles-National Airport?

What is the cheapest month to fly to Brussels Bruxelles-National Airport?

How far in advance should I book a flight from Panama City to Brussels Bruxelles-National Airport?

How have Panama City to Brussels Bruxelles-National Airport flight prices changed over time?

What is the cheapest airline that flies from Panama City Tocumen Intl to Brussels Bruxelles-National?

How often are flights from Panama City to Brussels delayed?

What is the most punctual flight time for Panama City to Brussels flights?

What day of the week experiences the fewest flight delays on this route?

Which airport is the most popular layover for flights between Panama City and Brussels Bruxelles-National Airport?

Which layover airport offers the lowest fares from Panama City to Brussels Bruxelles-National Airport?

Which layover airport has the shortest travel time from Panama City to Brussels Bruxelles-National Airport?

Which layover airport has the shortest connection time from Panama City to Brussels Bruxelles-National Airport?

When to book flights from Panama City to Brussels Bruxelles-National Airport

Cheap Panama City to Brussels Bruxelles-National Airport (PTY to BRU) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Panama City to Brussels Bruxelles-National Airport

Best airlines flying from Panama City to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from Panama City to Brussels Bruxelles-National Airport with momondo

Traveling to a place near Brussels?

Why use momondo?

An easier way to manage your Brussels Bruxelles-National Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Brussels

Popular cities in Belgium

Popular flights according to clicks in the last 7 days on momondo

Panama City flight routes

According to popular flight searches on momondo this year

Brussels Bruxelles-National Airport flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to Brussels

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Brussels

List of cabin classes available on flights landing in Brussels. Availability may vary depending on flight origin and airline.

Complete your trip to Brussels

Explore popular destinations other users love

According to popular flight searches on momondo this year