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Cheap flights from Panama City to Brussels from $669

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Brussels departing on 6/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama City to Brussels

Cheap round-trip flights

Enter your travel dates to find the best prices.
Turkish Airlines Logo
10:20 pm - 9:25 pm
PTY
-
BRU
40h 05m
1 stop
Turkish Airlines Logo
11:10 am - 8:25 pm
BRU
-
PTY
40h 15m
1 stop
$801Turkish Airlines
Mon, May 18 - Sun, May 24
Turkish Airlines Logo
10:20 pm - 5:50 pm
PTY
-
BRU
36h 30m
1 stop
Turkish Airlines Logo
2:25 pm - 8:25 pm
BRU
-
PTY
37h 00m
1 stop
$815Turkish Airlines
Wed, May 13 - Sun, May 17
Turkish Airlines Logo
10:20 pm - 1:25 pm
PTY
-
BRU
32h 05m
1 stop
Turkish Airlines Logo
4:15 pm - 6:30 pm
BRU
-
PTY
33h 15m
2 stops
$845Turkish Airlines
Mon, May 25 - Fri, May 29
Turkish Airlines Logo
10:20 pm - 1:25 pm
PTY
-
BRU
32h 05m
1 stop
Turkish Airlines Logo
4:15 pm - 6:30 pm
BRU
-
PTY
33h 15m
2 stops
$908Turkish Airlines
Mon, May 18 - Sun, May 24
Turkish Airlines Logo
10:20 pm - 3:15 pm
PTY
-
BRU
33h 55m
1 stop
Turkish Airlines Logo
2:25 pm - 6:30 pm
BRU
-
PTY
35h 05m
2 stops
$952Turkish Airlines
Wed, May 13 - Sun, May 17
United Airlines Logo
9:45 am - 7:45 am
PTY
-
BRU
15h 00m
1 stop
United Airlines Logo
11:10 am - 7:31 pm
BRU
-
PTY
15h 21m
1 stop
$1,057United Airlines
Mon, Aug 31 - Tue, Sep 8
Turkish Airlines Logo
10:20 pm - 10:10 am
PTY
-
BRU
28h 50m
1 stop
Turkish Airlines Logo
2:25 pm - 6:30 pm
BRU
-
PTY
35h 05m
2 stops
$1,103Turkish Airlines
Wed, May 13 - Sun, May 17
United Airlines Logo
10:00 am - 8:55 am
PTY
-
BRU
39h 55m
2 stops
United Airlines Logo
9:55 am - 7:31 pm
BRU
-
PTY
40h 36m
2 stops
$1,118United Airlines
Mon, May 18 - Sun, May 24
United Airlines Logo
10:00 am - 8:55 am
PTY
-
BRU
39h 55m
2 stops
United Airlines Logo
10:30 am - 7:31 pm
BRU
-
PTY
40h 01m
2 stops
$1,129United Airlines
Tue, Sep 1 - Mon, Sep 7
United Airlines Logo
9:45 am - 7:45 am
PTY
-
BRU
15h 00m
1 stop
United Airlines Logo
10:45 am - 7:31 pm
BRU
-
PTY
39h 46m
2 stops
$1,165United Airlines
Wed, Jul 22 - Wed, Jul 29

Lufthansa flights from Panama City to Brussels Bruxelles-National Airport

Our best Lufthansa deals on Panama City to Brussels Bruxelles-National Airport flight tickets
Lufthansa
Jul 15
PTY6:31 pmPanama City Tocumen Intl
19h 09m
2 stops
BRU8:40 pmBrussels Bruxelles-National
Jul 21
BRU7:30 pmBrussels Bruxelles-National
42h 20m
2 stops
PTY6:50 amPanama City Tocumen Intl
$1,781
Lufthansa
Jul 15
PTY6:31 pmPanama City Tocumen Intl
19h 09m
2 stops
BRU8:40 pmBrussels Bruxelles-National
Jul 21
BRU7:30 pmBrussels Bruxelles-National
42h 20m
2 stops
PTY6:50 amPanama City Tocumen Intl
$1,784

United Airlines flights from Panama City to Brussels Bruxelles-National Airport

Our best United Airlines deals on Panama City to Brussels Bruxelles-National Airport flight tickets
United Airlines
Aug 31
PTY10:00 amPanama City Tocumen Intl
38h 15m
2 stops
BRU7:15 amBrussels Bruxelles-National
Sep 8
BRU11:10 amBrussels Bruxelles-National
15h 21m
1 stop
PTY7:31 pmPanama City Tocumen Intl
$1,057
United Airlines
May 23
PTY10:00 amPanama City Tocumen Intl
20h 15m
2 stops
BRU1:15 pmBrussels Bruxelles-National
May 30
BRU12:00 pmBrussels Bruxelles-National
38h 31m
2 stops
PTY7:31 pmPanama City Tocumen Intl
$1,077
United Airlines
May 18
PTY10:00 amPanama City Tocumen Intl
39h 55m
2 stops
BRU8:55 amBrussels Bruxelles-National
May 24
BRU9:55 amBrussels Bruxelles-National
40h 36m
2 stops
PTY7:31 pmPanama City Tocumen Intl
$1,118

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Brussels Bruxelles-National Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 8, 2026.
Use the filters below to find and compare flights from Panama City to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 5/18

10:20 pm-9:25 pm

1 stop40h 05m

Brussels Bruxelles-National

Sun 5/24

11:10 am-8:25 pm

1 stop40h 15m

$801

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Wed 5/13

10:20 pm-5:50 pm

1 stop36h 30m

Brussels Bruxelles-National

Sun 5/17

2:25 pm-8:25 pm

1 stop37h 00m

$815

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 5/25

10:20 pm-1:25 pm

1 stop32h 05m

Brussels Bruxelles-National

Fri 5/29

4:15 pm-6:30 pm

2 stops33h 15m

$845

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 5/18

10:20 pm-1:25 pm

1 stop32h 05m

Brussels Bruxelles-National

Sun 5/24

4:15 pm-6:30 pm

2 stops33h 15m

$908

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Wed 5/13

10:20 pm-3:15 pm

1 stop33h 55m

Brussels Bruxelles-National

Sun 5/17

2:25 pm-6:30 pm

2 stops35h 05m

$952
Quickest round-trip

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 8/31

9:45 am-7:45 am

1 stop15h 00m

Brussels Bruxelles-National

Tue 9/8

11:10 am-7:31 pm

1 stop15h 21m

$1,057

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Wed 5/13

10:20 pm-10:10 am

1 stop28h 50m

Brussels Bruxelles-National

Sun 5/17

2:25 pm-6:30 pm

2 stops35h 05m

$1,103

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 5/18

10:00 am-8:55 am

2 stops39h 55m

Brussels Bruxelles-National

Sun 5/24

9:55 am-7:31 pm

2 stops40h 36m

$1,118

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Tue 9/1

10:00 am-8:55 am

2 stops39h 55m

Brussels Bruxelles-National

Mon 9/7

10:30 am-7:31 pm

2 stops40h 01m

$1,129

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Wed 7/22

9:45 am-7:45 am

1 stop15h 00m

Brussels Bruxelles-National

Wed 7/29

10:45 am-7:31 pm

2 stops39h 46m

$1,165

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Brussels from

How to get the cheapest flight ticket from Panama City to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Brussels Bruxelles-National Airport?

What is the cheapest month to fly to Brussels Bruxelles-National Airport?

The cheapest month to fly to Brussels Bruxelles-National Airport from Panama City is in February. Flight prices, which tend to average around $809, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of February, then book flights to Brussels Bruxelles-National Airport from Panama City during October instead. Flights to Brussels Bruxelles-National Airport in October, while not as cheap as those in February, still average around $814.

How far in advance should I book a flight to Brussels Bruxelles-National Airport?

You are more likely to see cheaper flights to Brussels Bruxelles-National Airport from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Brussels Bruxelles-National Airport for around $936 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Brussels Bruxelles-National Airport from Panama City for as low as $710 on momondo.

How have Panama City to Brussels Bruxelles-National Airport flight prices changed over time?

As of April 2026, prices for Panama City to Brussels Bruxelles-National Airport flights are approximately 6% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Brussels Bruxelles-National Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Brussels Bruxelles-National Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Brussels Bruxelles-National Airport (PTY to BRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Brussels Bruxelles-National Airport

Fastest flight time

19h 55m

Direct flights

None
The fastest flight from Panama City to Brussels Bruxelles-National Airport takes 19h 55m
There are no direct flights from Panama City to Brussels Bruxelles-National Airport. There are no popular flight routes from Panama City to Brussels Bruxelles-National Airport.
Search flight deals

Frequently asked questions about flying from Panama City to Brussels Bruxelles-National Airport

  • How far is Panama City Tocumen Intl to Brussels Bruxelles-National by plane?

    The distance between Panama City Tocumen Intl and Brussels Bruxelles-National is about 5473.2 mi. 19h 55m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport.

  • What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

    The required travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Brussels Bruxelles-National Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Brussels Bruxelles-National Airport?

Best airlines flying from Panama City to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from Panama City to Brussels Bruxelles-National Airport with momondo
Airline
Rating
Free Cancellation
Price
Air FrancePriceFrom $785Free CancellationRating
7.4
1,564 reviews
Search Air France flights
Air EuropaPriceFrom $808Free CancellationRating
6.9
597 reviews
Search Air Europa flights

Traveling to a place near Brussels?

Book flights to Brussels if you plan to visit one of these locations
Ghent
Bruges
Leuven
Charleroi
Zaventem
Hasselt
Namur
Genk
Waterloo
Dinant
Durbuy
Mons
Aalst
Mechelen
Knokke-Heist
Spa
Francorchamps
Tournai
Oostkamp
Halle

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Brussels?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Brussels. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Brussels with flexible booking policies on momondo?

Yes. All flights to Brussels from Panama City on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama City to Brussels?

Once you have performed a search for Panama City to Brussels flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Brussels right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Brussels flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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