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Cheap flights from Panama City to Brussels from $477

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Brussels departing on 2/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama City to Brussels

Cheap round-trip flights

Enter your travel dates to find the best prices.
Turkish Airlines Logo
9:45 pm - 10:10 pm
PTY
-
BRU
18h 25m1 stop
Turkish Airlines Logo
6:20 pm - 5:05 pm
BRU
-
PTY
28h 45m2 stops
$741Turkish Airlines
Sat, Feb 14 - Thu, Feb 26
Turkish Airlines Logo
9:45 pm - 10:10 pm
PTY
-
BRU
18h 25m1 stop
Turkish Airlines Logo
6:20 pm - 5:05 pm
BRU
-
PTY
28h 45m2 stops
$771Turkish Airlines
Sat, Feb 14 - Thu, Feb 26
Turkish Airlines Logo
9:45 pm - 5:20 pm
PTY
-
BRU
37h 35m1 stop
Turkish Airlines Logo
7:50 am - 5:05 pm
BRU
-
PTY
39h 15m2 stops
$777Turkish Airlines
Mon, Mar 9 - Thu, Mar 12
Turkish Airlines Logo
6:45 pm - 2:15 pm
PTY
-
BRU
37h 30m1 stop
Turkish Airlines Logo
7:20 am - 8:25 pm
BRU
-
PTY
20h 05m1 stop
$802Turkish Airlines
Thu, Mar 19 - Wed, Apr 1
Turkish Airlines Logo
6:45 pm - 10:10 pm
PTY
-
BRU
21h 25m1 stop
Turkish Airlines Logo
11:10 am - 6:30 pm
BRU
-
PTY
38h 20m2 stops
$813Turkish Airlines
Thu, Mar 19 - Wed, Apr 1
Turkish Airlines Logo
10:20 pm - 9:25 pm
PTY
-
BRU
40h 05m1 stop
Turkish Airlines Logo
6:55 pm - 8:25 pm
BRU
-
PTY
32h 30m1 stop
$815Turkish Airlines
Wed, May 6 - Sun, May 10
Turkish Airlines Logo
6:45 pm - 10:10 pm
PTY
-
BRU
21h 25m1 stop
Turkish Airlines Logo
6:20 pm - 5:05 pm
BRU
-
PTY
28h 45m2 stops
$824Turkish Airlines
Sun, Feb 1 - Thu, Feb 5
Turkish Airlines Logo
10:20 pm - 9:25 pm
PTY
-
BRU
40h 05m1 stop
Turkish Airlines Logo
2:25 pm - 6:25 pm
BRU
-
PTY
35h 00m2 stops
$826Turkish Airlines
Mon, Apr 13 - Sat, Apr 25
Turkish Airlines Logo
9:45 pm - 10:10 pm
PTY
-
BRU
18h 25m1 stop
Turkish Airlines Logo
6:20 pm - 5:05 pm
BRU
-
PTY
28h 45m2 stops
$827Turkish Airlines
Sat, Feb 14 - Thu, Feb 26
Turkish Airlines Logo
9:45 pm - 2:15 pm
PTY
-
BRU
34h 30m1 stop
Turkish Airlines Logo
11:35 am - 5:05 pm
BRU
-
PTY
35h 30m2 stops
$845Turkish Airlines
Sat, Feb 14 - Thu, Feb 26

KLM flights from Panama City to Brussels Bruxelles-National Airport

Our best KLM deals on Panama City to Brussels Bruxelles-National Airport flight tickets
KLM
Feb 14
PTY6:45 pmPanama City Tocumen Intl
21h 35m
1 stop
BRU10:20 pmBrussels Bruxelles-National
Feb 26
BRU8:05 amBrussels Bruxelles-National
14h 25m
1 stop
PTY4:30 pmPanama City Tocumen Intl
$968
Find similar
KLM
Feb 14
PTY6:45 pmPanama City Tocumen Intl
21h 35m
1 stop
BRU10:20 pmBrussels Bruxelles-National
Feb 26
BRU2:45 pmBrussels Bruxelles-National
31h 45m
1 stop
PTY4:30 pmPanama City Tocumen Intl
$975
Find similar
KLM
Feb 1
PTY6:45 pmPanama City Tocumen Intl
21h 35m
1 stop
BRU10:20 pmBrussels Bruxelles-National
Feb 5
BRU2:45 pmBrussels Bruxelles-National
31h 45m
1 stop
PTY4:30 pmPanama City Tocumen Intl
$1,070
Find similar

Turkish Airlines flights from Panama City to Brussels Bruxelles-National Airport

Our best Turkish Airlines deals on Panama City to Brussels Bruxelles-National Airport flight tickets
Turkish Airlines
Feb 14
PTY9:45 pmPanama City Tocumen Intl
18h 25m
1 stop
BRU10:10 pmBrussels Bruxelles-National
Feb 26
BRU6:20 pmBrussels Bruxelles-National
28h 45m
2 stops
PTY5:05 pmPanama City Tocumen Intl
$741
Find similar
Turkish Airlines
Feb 14
PTY9:45 pmPanama City Tocumen Intl
18h 25m
1 stop
BRU10:10 pmBrussels Bruxelles-National
Feb 26
BRU6:20 pmBrussels Bruxelles-National
28h 45m
2 stops
PTY5:05 pmPanama City Tocumen Intl
$771
Find similar
Turkish Airlines
Mar 9
PTY9:45 pmPanama City Tocumen Intl
37h 35m
1 stop
BRU5:20 pmBrussels Bruxelles-National
Mar 12
BRU7:50 amBrussels Bruxelles-National
39h 15m
2 stops
PTY5:05 pmPanama City Tocumen Intl
$777
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Brussels Bruxelles-National Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 31, 2025.
Use the filters below to find and compare flights from Panama City to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 2/14

9:45 pm-10:10 pm

1 stop18h 25m

Brussels Bruxelles-National

Thu 2/26

6:20 pm-5:05 pm

2 stops28h 45m

$741

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 2/14

9:45 pm-10:10 pm

1 stop18h 25m

Brussels Bruxelles-National

Thu 2/26

6:20 pm-5:05 pm

2 stops28h 45m

$771

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 3/9

9:45 pm-5:20 pm

1 stop37h 35m

Brussels Bruxelles-National

Thu 3/12

7:50 am-5:05 pm

2 stops39h 15m

$777

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Thu 3/19

6:45 pm-2:15 pm

1 stop37h 30m

Brussels Bruxelles-National

Wed 4/1

7:20 am-8:25 pm

1 stop20h 05m

$802

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Thu 3/19

6:45 pm-10:10 pm

1 stop21h 25m

Brussels Bruxelles-National

Wed 4/1

11:10 am-6:30 pm

2 stops38h 20m

$813

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Wed 5/6

10:20 pm-9:25 pm

1 stop40h 05m

Brussels Bruxelles-National

Sun 5/10

6:55 pm-8:25 pm

1 stop32h 30m

$815

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 2/1

6:45 pm-10:10 pm

1 stop21h 25m

Brussels Bruxelles-National

Thu 2/5

6:20 pm-5:05 pm

2 stops28h 45m

$824

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 4/13

10:20 pm-9:25 pm

1 stop40h 05m

Brussels Bruxelles-National

Sat 4/25

2:25 pm-6:25 pm

2 stops35h 00m

$826

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 2/14

9:45 pm-10:10 pm

1 stop18h 25m

Brussels Bruxelles-National

Thu 2/26

6:20 pm-5:05 pm

2 stops28h 45m

$827

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 2/14

9:45 pm-2:15 pm

1 stop34h 30m

Brussels Bruxelles-National

Thu 2/26

11:35 am-5:05 pm

2 stops35h 30m

$845

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Brussels from

How to get the cheapest flight ticket from Panama City to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Brussels Bruxelles-National Airport?

What is the cheapest month to fly to Brussels Bruxelles-National Airport?

The cheapest month to fly to Brussels Bruxelles-National Airport from Panama City is in January. Flight prices, which tend to average around $742, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to Brussels Bruxelles-National Airport from Panama City during March instead. Flights to Brussels Bruxelles-National Airport in March, while not as cheap as those in January, still average around $749.

How far in advance should I book a flight to Brussels Bruxelles-National Airport?

You are more likely to see cheaper flights to Brussels Bruxelles-National Airport from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Brussels Bruxelles-National Airport for around $868 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Brussels Bruxelles-National Airport from Panama City for as low as $773 on momondo.

How have Panama City to Brussels Bruxelles-National Airport flight prices changed over time?

As of December 2025, prices for Panama City to Brussels Bruxelles-National Airport flights are approximately 5% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Brussels Bruxelles-National Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Brussels Bruxelles-National Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Brussels Bruxelles-National Airport (PTY to BRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Brussels Bruxelles-National Airport

Fastest flight time

14h 15m

Direct flights

None
The fastest flight from Panama City to Brussels Bruxelles-National Airport takes 14h 15m
There are no direct flights from Panama City to Brussels Bruxelles-National Airport. There are no popular flight routes from Panama City to Brussels Bruxelles-National Airport.
Search flight deals

  • How far is Panama City Tocumen Intl to Brussels Bruxelles-National by plane?

    The distance between Panama City Tocumen Intl and Brussels Bruxelles-National is about 5473.2 mi. 14h 15m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport.

  • What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

    The required travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Brussels Bruxelles-National Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Brussels Bruxelles-National Airport?

Best airlines flying from Panama City to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from Panama City to Brussels Bruxelles-National Airport with momondo
Airline
Rating
Free Cancellation
Price
Air FrancePriceFrom $785Free CancellationRating
7.4
1,514 reviews
Search Air France flights
Air EuropaPriceFrom $797Free CancellationRating
7.0
575 reviews
Search Air Europa flights

Traveling to a place near Brussels?

Book flights to Brussels if you plan to visit one of these locations
Ghent
Bruges
Leuven
Charleroi
Hasselt
Spa
Zaventem
Namur
Dinant
Genk
Mons
Durbuy
Waterloo
Aalst
Mechelen
Francorchamps
Knokke-Heist
Tournai
Oostkamp
Halle

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Brussels?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Brussels. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Brussels with flexible booking policies on momondo?

Yes. All flights to Brussels from Panama City on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama City to Brussels?

Once you have performed a search for Panama City to Brussels flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Brussels right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Brussels flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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