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Cheap flights from Panama City to Brussels from $647

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Brussels departing on 7/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama City to Brussels

Cheap round-trip flights

Enter your travel dates to find the best prices.
Turkish Airlines Logo
9:45 pm - 5:20 pm
PTY
-
BRU
37h 35m
1 stop
Turkish Airlines Logo
3:15 pm - 5:05 pm
BRU
-
PTY
31h 50m
2 stops
$740Turkish Airlines
Sat, Feb 14 - Thu, Feb 26
Turkish Airlines Logo
9:45 pm - 10:10 pm
PTY
-
BRU
18h 25m
1 stop
Turkish Airlines Logo
6:20 pm - 5:05 pm
BRU
-
PTY
28h 45m
2 stops
$770Turkish Airlines
Sat, Feb 14 - Thu, Feb 26
Turkish Airlines Logo
9:45 pm - 5:20 pm
PTY
-
BRU
37h 35m
1 stop
Turkish Airlines Logo
6:20 pm - 5:05 pm
BRU
-
PTY
28h 45m
2 stops
$771Turkish Airlines
Sat, Feb 14 - Thu, Feb 26
Turkish Airlines Logo
10:20 pm - 9:25 pm
PTY
-
BRU
40h 05m
1 stop
Turkish Airlines Logo
2:25 pm - 8:25 pm
BRU
-
PTY
37h 00m
1 stop
$784Turkish Airlines
Sat, Apr 11 - Tue, May 5
Turkish Airlines Logo
10:20 pm - 9:25 pm
PTY
-
BRU
40h 05m
1 stop
Turkish Airlines Logo
7:20 am - 8:25 pm
BRU
-
PTY
20h 05m
1 stop
$795Turkish Airlines
Sat, Apr 11 - Mon, May 4
Turkish Airlines Logo
9:45 pm - 2:15 pm
PTY
-
BRU
34h 30m
1 stop
Turkish Airlines Logo
6:20 pm - 5:05 pm
BRU
-
PTY
28h 45m
2 stops
$796Turkish Airlines
Mon, Mar 2 - Mon, Mar 23
Turkish Airlines Logo
8:05 pm - 9:25 pm
PTY
-
BRU
18h 20m
1 stop
Turkish Airlines Logo
7:20 am - 8:25 pm
BRU
-
PTY
20h 05m
1 stop
$806Turkish Airlines
Sun, Apr 12 - Wed, Apr 29
Turkish Airlines Logo
9:45 pm - 10:35 am
PTY
-
BRU
30h 50m
1 stop
Turkish Airlines Logo
6:20 pm - 5:05 pm
BRU
-
PTY
28h 45m
2 stops
$807Turkish Airlines
Mon, Mar 2 - Sat, Mar 21
Turkish Airlines Logo
10:20 pm - 5:55 pm
PTY
-
BRU
36h 35m
1 stop
Turkish Airlines Logo
7:20 am - 8:25 pm
BRU
-
PTY
20h 05m
1 stop
$814Turkish Airlines
Mon, Apr 13 - Sat, Apr 25
Turkish Airlines Logo
9:45 pm - 2:15 pm
PTY
-
BRU
34h 30m
1 stop
Turkish Airlines Logo
4:15 pm - 8:25 pm
BRU
-
PTY
35h 10m
1 stop
$815Turkish Airlines
Mon, Mar 2 - Sun, Mar 29

Turkish Airlines flights from Panama City to Brussels Bruxelles-National Airport

Our best Turkish Airlines deals on Panama City to Brussels Bruxelles-National Airport flight tickets
Turkish Airlines
Feb 14
PTY9:45 pmPanama City Tocumen Intl
37h 35m
1 stop
BRU5:20 pmBrussels Bruxelles-National
Feb 26
BRU3:15 pmBrussels Bruxelles-National
31h 50m
2 stops
PTY5:05 pmPanama City Tocumen Intl
$740
Turkish Airlines
Feb 14
PTY9:45 pmPanama City Tocumen Intl
18h 25m
1 stop
BRU10:10 pmBrussels Bruxelles-National
Feb 26
BRU6:20 pmBrussels Bruxelles-National
28h 45m
2 stops
PTY5:05 pmPanama City Tocumen Intl
$770
Turkish Airlines
Feb 14
PTY9:45 pmPanama City Tocumen Intl
37h 35m
1 stop
BRU5:20 pmBrussels Bruxelles-National
Feb 26
BRU6:20 pmBrussels Bruxelles-National
28h 45m
2 stops
PTY5:05 pmPanama City Tocumen Intl
$771

Air Europa flights from Panama City to Brussels Bruxelles-National Airport

Our best Air Europa deals on Panama City to Brussels Bruxelles-National Airport flight tickets
Air Europa
Apr 12
PTY8:25 pmPanama City Tocumen Intl
30h 20m
1 stop
BRU9:45 amBrussels Bruxelles-National
Apr 30
BRU10:45 amBrussels Bruxelles-National
14h 55m
1 stop
PTY6:40 pmPanama City Tocumen Intl
$836
Air Europa
Apr 10
PTY8:25 pmPanama City Tocumen Intl
30h 20m
1 stop
BRU9:45 amBrussels Bruxelles-National
May 4
BRU10:45 amBrussels Bruxelles-National
14h 55m
1 stop
PTY6:40 pmPanama City Tocumen Intl
$874
Air Europa
Apr 10
PTY8:25 pmPanama City Tocumen Intl
30h 20m
1 stop
BRU9:45 amBrussels Bruxelles-National
May 3
BRU6:55 pmBrussels Bruxelles-National
30h 45m
1 stop
PTY6:40 pmPanama City Tocumen Intl
$884

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Brussels Bruxelles-National Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Panama City to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 2/14

9:45 pm-5:20 pm

1 stop37h 35m

Brussels Bruxelles-National

Thu 2/26

3:15 pm-5:05 pm

2 stops31h 50m

$740

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 2/14

9:45 pm-10:10 pm

1 stop18h 25m

Brussels Bruxelles-National

Thu 2/26

6:20 pm-5:05 pm

2 stops28h 45m

$770

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 2/14

9:45 pm-5:20 pm

1 stop37h 35m

Brussels Bruxelles-National

Thu 2/26

6:20 pm-5:05 pm

2 stops28h 45m

$771

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 4/11

10:20 pm-9:25 pm

1 stop40h 05m

Brussels Bruxelles-National

Tue 5/5

2:25 pm-8:25 pm

1 stop37h 00m

$784

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 4/11

10:20 pm-9:25 pm

1 stop40h 05m

Brussels Bruxelles-National

Mon 5/4

7:20 am-8:25 pm

1 stop20h 05m

$795

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 3/2

9:45 pm-2:15 pm

1 stop34h 30m

Brussels Bruxelles-National

Mon 3/23

6:20 pm-5:05 pm

2 stops28h 45m

$796

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 4/12

8:05 pm-9:25 pm

1 stop18h 20m

Brussels Bruxelles-National

Wed 4/29

7:20 am-8:25 pm

1 stop20h 05m

$806

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 3/2

9:45 pm-10:35 am

1 stop30h 50m

Brussels Bruxelles-National

Sat 3/21

6:20 pm-5:05 pm

2 stops28h 45m

$807

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 4/13

10:20 pm-5:55 pm

1 stop36h 35m

Brussels Bruxelles-National

Sat 4/25

7:20 am-8:25 pm

1 stop20h 05m

$814

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 3/2

9:45 pm-2:15 pm

1 stop34h 30m

Brussels Bruxelles-National

Sun 3/29

4:15 pm-8:25 pm

1 stop35h 10m

$815

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Brussels from

How to get the cheapest flight ticket from Panama City to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Brussels Bruxelles-National Airport?

The cheapest month to fly to Brussels Bruxelles-National Airport from Panama City is in February. Flight prices, which tend to average around $808, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of February, then book flights to Brussels Bruxelles-National Airport from Panama City during September instead. Flights to Brussels Bruxelles-National Airport in September, while not as cheap as those in February, still average around $811.

How far in advance should I book a flight to Brussels Bruxelles-National Airport?

You are more likely to see cheaper flights to Brussels Bruxelles-National Airport from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Brussels Bruxelles-National Airport for around $894 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Brussels Bruxelles-National Airport from Panama City for as low as $782 on momondo.

How have Panama City to Brussels Bruxelles-National Airport flight prices changed over time?

As of January 2026, prices for Panama City to Brussels Bruxelles-National Airport flights are approximately 99% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Brussels Bruxelles-National Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Brussels Bruxelles-National Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Brussels Bruxelles-National Airport (PTY to BRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Brussels Bruxelles-National Airport

Fastest flight time

14h 15m

Direct flights

None
The fastest flight from Panama City to Brussels Bruxelles-National Airport takes 14h 15m
There are no direct flights from Panama City to Brussels Bruxelles-National Airport. There are no popular flight routes from Panama City to Brussels Bruxelles-National Airport.
Search flight deals

  • How far is Panama City Tocumen Intl to Brussels Bruxelles-National by plane?

    The distance between Panama City Tocumen Intl and Brussels Bruxelles-National is about 5473.2 mi. 14h 15m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport.

  • What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

    The required travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Brussels Bruxelles-National Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Brussels Bruxelles-National Airport?

Best airlines flying from Panama City to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from Panama City to Brussels Bruxelles-National Airport with momondo
Airline
Rating
Free Cancellation
Price
Air FrancePriceFrom $785Free CancellationRating
7.4
1,528 reviews
Search Air France flights
Air EuropaPriceFrom $797Free CancellationRating
6.9
587 reviews
Search Air Europa flights

Traveling to a place near Brussels?

Book flights to Brussels if you plan to visit one of these locations
Ghent
Bruges
Leuven
Charleroi
Zaventem
Hasselt
Spa
Namur
Dinant
Genk
Mons
Waterloo
Durbuy
Aalst
Knokke-Heist
Mechelen
Francorchamps
Tournai
Oostkamp
Halle

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Brussels?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Brussels. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Brussels with flexible booking policies on momondo?

Yes. All flights to Brussels from Panama City on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama City to Brussels?

Once you have performed a search for Panama City to Brussels flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Brussels right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Brussels flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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