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Cheap flights from Panama City to Brussels from $856

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Brussels departing on 11/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Panama City to Brussels

Cheap round-trip flights

Enter your travel dates to find the best prices.
Turkish Airlines Logo
6:50 pm - 2:15 pm
PTY
-
BRU
37h 25m
1 stop
Turkish Airlines Logo
3:15 pm - 8:05 pm
BRU
-
PTY
34h 50m
1 stop
$856Turkish Airlines
Thu, Nov 5 - Thu, Nov 26
Turkish Airlines Logo
9:45 pm - 5:10 pm
PTY
-
BRU
37h 25m
1 stop
Turkish Airlines Logo
3:15 pm - 8:05 pm
BRU
-
PTY
34h 50m
1 stop
$898Turkish Airlines
Sat, Nov 7 - Sun, Nov 15
KLM Logo
6:50 pm - 2:40 pm
PTY
-
BRU
12h 50m
1 stop
KLM Logo
8:05 am - 7:45 pm
BRU
-
PTY
18h 40m
2 stops
$914KLM
Sun, Oct 4 - Sun, Oct 11
Turkish Airlines Logo
10:00 pm - 2:15 pm
PTY
-
BRU
34h 15m
1 stop
Turkish Airlines Logo
3:15 pm - 8:05 pm
BRU
-
PTY
34h 50m
1 stop
$919Turkish Airlines
Wed, Nov 18 - Sun, Nov 22
KLM Logo
9:55 pm - 10:15 pm
PTY
-
BRU
17h 20m
2 stops
KLM Logo
10:35 am - 7:45 pm
BRU
-
PTY
16h 10m
2 stops
$933KLM
Sun, Oct 4 - Sun, Oct 11
Turkish Airlines Logo
10:20 pm - 3:15 pm
PTY
-
BRU
33h 55m
1 stop
Turkish Airlines Logo
2:25 pm - 8:25 pm
BRU
-
PTY
37h 00m
1 stop
$949Turkish Airlines
Wed, Oct 7 - Sun, Oct 11
KLM Logo
6:50 pm - 2:40 pm
PTY
-
BRU
12h 50m
1 stop
KLM Logo
8:05 am - 7:45 pm
BRU
-
PTY
18h 40m
2 stops
$964KLM
Sun, Oct 4 - Sun, Oct 11
KLM Logo
6:50 pm - 2:40 pm
PTY
-
BRU
12h 50m
1 stop
KLM Logo
8:05 am - 7:45 pm
BRU
-
PTY
18h 40m
2 stops
$976KLM
Sun, Oct 4 - Sun, Oct 11
KLM Logo
9:55 pm - 10:15 pm
PTY
-
BRU
17h 20m
2 stops
KLM Logo
8:05 am - 7:45 pm
BRU
-
PTY
18h 40m
2 stops
$979KLM
Sun, Oct 4 - Sun, Oct 11
KLM Logo
6:50 pm - 2:40 pm
PTY
-
BRU
12h 50m
1 stop
KLM Logo
8:05 am - 7:45 pm
BRU
-
PTY
18h 40m
2 stops
$985KLM
Sun, Oct 4 - Sun, Oct 11

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United Airlines flights from Panama City to Brussels Bruxelles-National Airport

Our best United Airlines deals on Panama City to Brussels Bruxelles-National Airport flight tickets
United Airlines
Jul 20
PTY10:55 pmPanama City Tocumen Intl
25h 50m
1 stop
BRU7:45 amBrussels Bruxelles-National
Aug 2
BRU10:45 amBrussels Bruxelles-National
24h 19m
2 stops
PTY4:04 amPanama City Tocumen Intl
$1,073
United Airlines
Jul 20
PTY9:45 amPanama City Tocumen Intl
15h 00m
1 stop
BRU7:45 amBrussels Bruxelles-National
Aug 2
BRU11:10 amBrussels Bruxelles-National
23h 54m
1 stop
PTY4:04 amPanama City Tocumen Intl
$1,074
United Airlines
Jul 20
PTY9:45 amPanama City Tocumen Intl
15h 00m
1 stop
BRU7:45 amBrussels Bruxelles-National
Aug 3
BRU11:10 amBrussels Bruxelles-National
23h 54m
1 stop
PTY4:04 amPanama City Tocumen Intl
$1,078

Turkish Airlines flights from Panama City to Brussels Bruxelles-National Airport

Our best Turkish Airlines deals on Panama City to Brussels Bruxelles-National Airport flight tickets
Turkish Airlines
Nov 5
PTY6:50 pmPanama City Tocumen Intl
37h 25m
1 stop
BRU2:15 pmBrussels Bruxelles-National
Nov 26
BRU3:15 pmBrussels Bruxelles-National
34h 50m
1 stop
PTY8:05 pmPanama City Tocumen Intl
$856
Turkish Airlines
Nov 7
PTY9:45 pmPanama City Tocumen Intl
37h 25m
1 stop
BRU5:10 pmBrussels Bruxelles-National
Nov 15
BRU3:15 pmBrussels Bruxelles-National
34h 50m
1 stop
PTY8:05 pmPanama City Tocumen Intl
$898
Turkish Airlines
Nov 18
PTY10:00 pmPanama City Tocumen Intl
34h 15m
1 stop
BRU2:15 pmBrussels Bruxelles-National
Nov 22
BRU3:15 pmBrussels Bruxelles-National
34h 50m
1 stop
PTY8:05 pmPanama City Tocumen Intl
$919

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Brussels Bruxelles-National Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from Panama City to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Thu 11/5

6:50 pm-2:15 pm

1 stop37h 25m

Brussels Bruxelles-National

Thu 11/26

3:15 pm-8:05 pm

1 stop34h 50m

$856

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 11/7

9:45 pm-5:10 pm

1 stop37h 25m

Brussels Bruxelles-National

Sun 11/15

3:15 pm-8:05 pm

1 stop34h 50m

$898
Quickest round-trip

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 10/4

6:50 pm-2:40 pm

1 stop12h 50m

Brussels Bruxelles-National

Sun 10/11

8:05 am-7:45 pm

2 stops18h 40m

$914

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Wed 11/18

10:00 pm-2:15 pm

1 stop34h 15m

Brussels Bruxelles-National

Sun 11/22

3:15 pm-8:05 pm

1 stop34h 50m

$919

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 10/4

9:55 pm-10:15 pm

2 stops17h 20m

Brussels Bruxelles-National

Sun 10/11

10:35 am-7:45 pm

2 stops16h 10m

$933

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Wed 10/7

10:20 pm-3:15 pm

1 stop33h 55m

Brussels Bruxelles-National

Sun 10/11

2:25 pm-8:25 pm

1 stop37h 00m

$949

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 10/4

6:50 pm-2:40 pm

1 stop12h 50m

Brussels Bruxelles-National

Sun 10/11

8:05 am-7:45 pm

2 stops18h 40m

$964

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 10/4

6:50 pm-2:40 pm

1 stop12h 50m

Brussels Bruxelles-National

Sun 10/11

8:05 am-7:45 pm

2 stops18h 40m

$976

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 10/4

9:55 pm-10:15 pm

2 stops17h 20m

Brussels Bruxelles-National

Sun 10/11

8:05 am-7:45 pm

2 stops18h 40m

$979

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 10/4

6:50 pm-2:40 pm

1 stop12h 50m

Brussels Bruxelles-National

Sun 10/11

8:05 am-7:45 pm

2 stops18h 40m

$985

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Brussels from

How to get the cheapest flight ticket from Panama City to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Brussels Bruxelles-National Airport?

What is the cheapest month to fly to Brussels Bruxelles-National Airport?

The cheapest month to fly to Brussels Bruxelles-National Airport from Panama City is in September. Flight prices, which tend to average around $807, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to Brussels Bruxelles-National Airport from Panama City during February instead. Flights to Brussels Bruxelles-National Airport in February, while not as cheap as those in September, still average around $809.

How far in advance should I book a flight from Panama City to Brussels Bruxelles-National Airport?

You are more likely to see cheaper flights to Brussels Bruxelles-National Airport from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Brussels Bruxelles-National Airport for around $972 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Brussels Bruxelles-National Airport from Panama City for as low as $746 on momondo.

How have Panama City to Brussels Bruxelles-National Airport flight prices changed over time?

As of June 2026, prices for Panama City to Brussels Bruxelles-National Airport flights are approximately 8% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Brussels Bruxelles-National Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Brussels Bruxelles-National Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Brussels Bruxelles-National Airport (PTY to BRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Brussels Bruxelles-National Airport

Fastest flight time

40h 05m

Direct flights

None
The fastest flight from Panama City to Brussels Bruxelles-National Airport takes 40h 05m
There are no direct flights from Panama City to Brussels Bruxelles-National Airport. There are no popular flight routes from Panama City to Brussels Bruxelles-National Airport.
Search flight deals

Frequently asked questions about flying from Panama City to Brussels Bruxelles-National Airport

  • How far is Panama City Tocumen Intl to Brussels Bruxelles-National by plane?

    The distance between Panama City Tocumen Intl and Brussels Bruxelles-National is about 5473.2 mi. 40h 05m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport.

  • What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

    The required travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Brussels Bruxelles-National Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Brussels Bruxelles-National Airport?

Best airlines flying from Panama City to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from Panama City to Brussels Bruxelles-National Airport with momondo
Airline
Rating
Free Cancellation
Price
Air EuropaPriceFrom $808Free CancellationRating
7.0
618 reviews
Search Air Europa flights

Traveling to a place near Brussels?

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Bruges
Ghent
Leuven
Charleroi
Zaventem
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Hasselt
Durbuy
Dinant
Genk
Namur
Waterloo
Aalst
Mechelen
Knokke-Heist
Francorchamps
Spa
Tournai
Oostkamp
Halle

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Brussels?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Brussels. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Brussels with flexible booking policies on momondo?

Yes. All flights to Brussels from Panama City on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama City to Brussels?

Once you have performed a search for Panama City to Brussels flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Brussels right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Brussels flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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