What is the most punctual flight time for Panama City to Brussels flights?

Generally, flights departing at night tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

Which layover airport has the shortest travel time from Panama City to Brussels Bruxelles-National Airport?

Flights connecting via Amsterdam (AMS) have the shortest average one-way travel time: 12h 50m.

Which layover airport has the shortest connection time from Panama City to Brussels Bruxelles-National Airport?

Amsterdam (AMS) has the shortest average layover time for this route: 1h 40m.

Which layover airport offers the lowest fares from Panama City to Brussels Bruxelles-National Airport?

Flights via Madrid (MAD) offer the lowest average round-trip price of $734.

Which airport is the most popular layover for flights between Panama City and Brussels Bruxelles-National Airport?

Amsterdam (AMS) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

What day of the week experiences the fewest flight delays on this route?

Wednesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Wednesday has historically seen more delays on average compared to the rest of the week.

How often are flights from Panama City to Brussels delayed?

Historically, on average around 0% of flights between Panama City and Brussels have experienced a delay on any given week. The average delay length over the past 12 months has been 0 minutes.

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

Prices for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport refresh daily.

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

As of July 2026, there is 1 operator available to choose from for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport.

How old do you have to be to fly from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport.

What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

The required travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Brussels Bruxelles-National Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$849 Cheap Flights from Panama City to Brussels Bruxelles-National Airport in 2026

Find the cheapest flights from Panama City to Brussels

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

10:00 pm - 5:10 pm

PTY

BRU

37h 10m

1 stop

6:30 am - 5:10 pm

BRU

PTY

40h 40m

2 stops

$849Turkish Airlines

Fri, Nov 6 - Fri, Nov 13

10:20 pm - 9:25 pm

PTY

BRU

40h 05m

1 stop

6:30 am - 5:10 pm

BRU

PTY

40h 40m

2 stops

$849Turkish Airlines

Fri, Oct 16 - Sun, Oct 25

10:00 pm - 10:20 pm

PTY

BRU

18h 20m

1 stop

6:30 am - 8:05 pm

BRU

PTY

19h 35m

1 stop

$849Turkish Airlines

Wed, Dec 9 - Mon, Dec 14

10:20 pm - 9:55 am

PTY

BRU

28h 35m

1 stop

7:20 am - 6:30 pm

BRU

PTY

42h 10m

2 stops

$849Turkish Airlines

Mon, Sep 7 - Sun, Sep 13

10:00 pm - 2:15 pm

PTY

BRU

34h 15m

1 stop

6:30 am - 8:05 pm

BRU

PTY

19h 35m

1 stop

$849Turkish Airlines

Fri, Nov 6 - Fri, Nov 13

10:00 pm - 10:35 am

PTY

BRU

30h 35m

1 stop

11:35 am - 8:05 pm

BRU

PTY

38h 30m

1 stop

$849Turkish Airlines

Mon, Nov 16 - Sun, Nov 29

10:20 pm - 5:55 pm

PTY

BRU

36h 35m

1 stop

6:15 pm - 8:05 pm

BRU

PTY

31h 50m

1 stop

$880Turkish Airlines

Fri, Sep 25 - Thu, Dec 10

10:20 pm - 1:25 pm

PTY

BRU

32h 05m

1 stop

3:15 pm - 8:05 pm

BRU

PTY

34h 50m

1 stop

$880Turkish Airlines

Fri, Sep 25 - Thu, Dec 10

8:25 pm - 5:40 pm

PTY

BRU

14h 15m

1 stop

10:45 am - 7:45 pm

BRU

PTY

15h 00m

1 stop

$934Air Europa

Wed, Oct 21 - Sun, Oct 25

8:25 pm - 9:45 am

PTY

BRU

30h 20m

1 stop

10:45 am - 6:40 pm

BRU

PTY

14h 55m

1 stop

$943Air Europa

Sun, Oct 4 - Sun, Oct 11

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Air Europa flights from Panama City to Brussels Bruxelles-National Airport

Our best Air Europa deals on Panama City to Brussels Bruxelles-National Airport flight tickets

Air Europa

Oct 21

PTY8:25 pmPanama City Tocumen Intl

14h 15m

1 stop

BRU5:40 pmBrussels Bruxelles-National

Oct 25

BRU10:45 amBrussels Bruxelles-National

15h 00m

1 stop

PTY7:45 pmPanama City Tocumen Intl

$934

Air Europa

Oct 4

PTY8:25 pmPanama City Tocumen Intl

14h 15m

1 stop

BRU5:40 pmBrussels Bruxelles-National

Oct 11

BRU6:55 pmBrussels Bruxelles-National

30h 45m

1 stop

PTY6:40 pmPanama City Tocumen Intl

$978

Air Europa

Sep 8

PTY8:25 pmPanama City Tocumen Intl

14h 15m

1 stop

BRU5:40 pmBrussels Bruxelles-National

Sep 21

BRU10:45 amBrussels Bruxelles-National

14h 55m

1 stop

PTY6:40 pmPanama City Tocumen Intl

$1,052

KLM flights from Panama City to Brussels Bruxelles-National Airport

Our best KLM deals on Panama City to Brussels Bruxelles-National Airport flight tickets

KLM

Oct 4

PTY6:50 pmPanama City Tocumen Intl

12h 50m

1 stop

BRU2:40 pmBrussels Bruxelles-National

Oct 11

BRU10:35 amBrussels Bruxelles-National

16h 10m

2 stops

PTY7:45 pmPanama City Tocumen Intl

$1,028

KLM

Oct 4

PTY9:55 pmPanama City Tocumen Intl

17h 20m

2 stops

BRU10:15 pmBrussels Bruxelles-National

Oct 11

BRU10:35 amBrussels Bruxelles-National

16h 10m

2 stops

PTY7:45 pmPanama City Tocumen Intl

$1,049

KLM

Oct 4

PTY6:50 pmPanama City Tocumen Intl

12h 50m

1 stop

BRU2:40 pmBrussels Bruxelles-National

Oct 11

BRU10:35 amBrussels Bruxelles-National

16h 10m

2 stops

PTY7:45 pmPanama City Tocumen Intl

$1,051

momondo Fare Finder

Use the filters below to find and compare flights from Panama City to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Fri 11/6

10:00 pm-5:10 pm

1 stop37h 10m

Brussels Bruxelles-National

Fri 11/13

6:30 am-5:10 pm

2 stops40h 40m

$849

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Fri 10/16

10:20 pm-9:25 pm

1 stop40h 05m

Brussels Bruxelles-National

Sun 10/25

6:30 am-5:10 pm

2 stops40h 40m

$849

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Wed 12/9

10:00 pm-10:20 pm

1 stop18h 20m

Brussels Bruxelles-National

Mon 12/14

6:30 am-8:05 pm

1 stop19h 35m

$849

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 9/7

10:20 pm-9:55 am

1 stop28h 35m

Brussels Bruxelles-National

Sun 9/13

7:20 am-6:30 pm

2 stops42h 10m

$849

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Fri 11/6

10:00 pm-2:15 pm

1 stop34h 15m

Brussels Bruxelles-National

Fri 11/13

6:30 am-8:05 pm

1 stop19h 35m

$849

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 11/16

10:00 pm-10:35 am

1 stop30h 35m

Brussels Bruxelles-National

Sun 11/29

11:35 am-8:05 pm

1 stop38h 30m

$849

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Fri 9/25

10:20 pm-5:55 pm

1 stop36h 35m

Brussels Bruxelles-National

Thu 12/10

6:15 pm-8:05 pm

1 stop31h 50m

$880

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Fri 9/25

10:20 pm-1:25 pm

1 stop32h 05m

Brussels Bruxelles-National

Thu 12/10

3:15 pm-8:05 pm

1 stop34h 50m

$880

Quickest round-trip

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Wed 10/21

8:25 pm-5:40 pm

1 stop14h 15m

Brussels Bruxelles-National

Sun 10/25

10:45 am-7:45 pm

1 stop15h 00m

$934

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 10/4

8:25 pm-9:45 am

1 stop30h 20m

Brussels Bruxelles-National

Sun 10/11

10:45 am-6:40 pm

1 stop14h 55m

$943

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Panama City to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Delays

Layovers

What is the typical price of a round-trip flight between Panama City and Brussels Bruxelles-National Airport?

Prices are currently low for flights on this route.

Typical prices usually range from $1,072 to $1,098.
The lowest price recently found on this route was $849.

What is the cheapest month to fly to Brussels Bruxelles-National Airport?

The cheapest month to fly to Brussels Bruxelles-National Airport from Panama City is in February. Flight prices, which tend to average around $809, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of February, then book flights to Brussels Bruxelles-National Airport from Panama City during March instead. Flights to Brussels Bruxelles-National Airport in March, while not as cheap as those in February, still average around $836.

How far in advance should I book a flight from Panama City to Brussels Bruxelles-National Airport?

You are more likely to see cheaper flights to Brussels Bruxelles-National Airport from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Brussels Bruxelles-National Airport for around $983 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Brussels Bruxelles-National Airport from Panama City for as low as $811 on momondo.

How have Panama City to Brussels Bruxelles-National Airport flight prices changed over time?

When to book flights from Panama City to Brussels Bruxelles-National Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Brussels Bruxelles-National Airport according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Panama City to Brussels Bruxelles-National Airport (PTY to BRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Brussels Bruxelles-National Airport

Fastest flight time	41h 45m
Direct flights	None

The fastest flight from Panama City to Brussels Bruxelles-National Airport takes 41h 45m

There are no direct flights from Panama City to Brussels Bruxelles-National Airport. There are no popular flight routes from Panama City to Brussels Bruxelles-National Airport.

Search flight deals

Frequently asked questions about flying from Panama City to Brussels Bruxelles-National Airport

How far is Panama City Tocumen Intl to Brussels Bruxelles-National by plane?
The distance between Panama City Tocumen Intl and Brussels Bruxelles-National is about 5473.2 mi. 41h 45m is a normal flight duration for this route.
When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?
Prices for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport refresh daily.
How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?
As of July 2026, there is 1 operator available to choose from for flights from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport.
How old do you have to be to fly from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Brussels Bruxelles-National Airport.
What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?
The required travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Brussels Bruxelles-National Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Panama City to Brussels Bruxelles-National Airport?
Based on momondo bookings for flights between Panama City and Brussels Bruxelles-National Airport, the leading airline is Air Europa, making up 100% of the total bookings.

Best airlines flying from Panama City to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from Panama City to Brussels Bruxelles-National Airport with momondo

Airline	Rating	Free Cancellation	Price
Air Europa	PriceFrom $797	Free Cancellation	Rating 7.0 629 reviews		Search Air Europa flights

Bruges

Ghent

Leuven

Dinant

Mons

Zaventem

Durbuy

Hasselt

Charleroi

Genk

Waterloo

Aalst

Namur

Knokke-Heist

Spa

Mechelen

Francorchamps

Tournai

Oostkamp

Halle

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Brussels?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Brussels. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Brussels with flexible booking policies on momondo?

Yes. All flights to Brussels from Panama City on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama City to Brussels?

Once you have performed a search for Panama City to Brussels flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Brussels right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Brussels flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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Flights to Charleroi Brussels Airportfrom $600

Cheap flights from Panama City to Brussels from $849

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Brussels departing on 11/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Air Europa flights from Panama City to Brussels Bruxelles-National Airport

Our best Air Europa deals on Panama City to Brussels Bruxelles-National Airport flight tickets

KLM flights from Panama City to Brussels Bruxelles-National Airport

Our best KLM deals on Panama City to Brussels Bruxelles-National Airport flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Panama City to Brussels Bruxelles-National Airport that are best for you.

See travel insights to Brussels from

How to get the cheapest flight ticket from Panama City to Brussels Bruxelles-National Airport

What is the typical price of a round-trip flight between Panama City and Brussels Bruxelles-National Airport?

What is the cheapest month to fly to Brussels Bruxelles-National Airport?

How far in advance should I book a flight from Panama City to Brussels Bruxelles-National Airport?

How have Panama City to Brussels Bruxelles-National Airport flight prices changed over time?

How often are flights from Panama City to Brussels delayed?

What is the most punctual flight time for Panama City to Brussels flights?

What day of the week experiences the fewest flight delays on this route?

Which airport is the most popular layover for flights between Panama City and Brussels Bruxelles-National Airport?

Which layover airport offers the lowest fares from Panama City to Brussels Bruxelles-National Airport?

Which layover airport has the shortest travel time from Panama City to Brussels Bruxelles-National Airport?

Which layover airport has the shortest connection time from Panama City to Brussels Bruxelles-National Airport?

When to book flights from Panama City to Brussels Bruxelles-National Airport

Cheap Panama City to Brussels Bruxelles-National Airport (PTY to BRU) flight deals and tips

Fastest flight time

Direct flights

Frequently asked questions about flying from Panama City to Brussels Bruxelles-National Airport

Best airlines flying from Panama City to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from Panama City to Brussels Bruxelles-National Airport with momondo

Traveling to a place near Brussels?

Why use momondo?

An easier way to manage your Brussels Bruxelles-National Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Brussels

Popular cities in Belgium

Popular flights according to clicks in the last 7 days on momondo

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According to popular flight searches on momondo this year

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List of cabin classes available on flights landing in Brussels. Availability may vary depending on flight origin and airline.

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