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Cheap flights from Ohio to Santa Cruz de la Sierra from $393

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Ohio to Santa Cruz de la Sierra departing on 12/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Ohio to Santa Cruz de la Sierra

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:10 am - 2:35 amDTW-VVI
18h 25m2 stops
Multiple Airlines Logo
3:40 am - 5:53 pmVVI-DTW
15h 13m2 stops
$713Multiple Airlines
Find Deal
Wed, Dec 3 - Fri, Dec 5
United Airlines Logo
6:30 am - 10:50 pmCVG-VVI
16h 20m2 stops
United Airlines Logo
11:44 am - 11:39 pmVVI-CVG
35h 55m2 stops
$752United Airlines
Find Deal
Sun, Apr 5 - Tue, Apr 7
United Airlines Logo
6:15 am - 3:44 amCLE-VVI
21h 29m2 stops
United Airlines Logo
11:44 am - 6:36 pmVVI-CLE
30h 52m2 stops
$772United Airlines
Find Deal
Sun, Apr 5 - Tue, Apr 7
United Airlines Logo
9:00 am - 10:50 pmDAY-VVI
37h 50m2 stops
United Airlines Logo
11:42 am - 1:24 pmVVI-DAY
25h 42m2 stops
$828United Airlines
Find Deal
Fri, Mar 20 - Tue, Mar 24
Multiple Airlines Logo
7:10 am - 2:35 amDTW-VVI
18h 25m2 stops
Multiple Airlines Logo
3:40 am - 8:23 pmVVI-DTW
17h 43m3 stops
$840Multiple Airlines
Find Deal
Wed, Dec 3 - Fri, Dec 5
Multiple Airlines Logo
6:00 am - 2:35 amCLE-VVI
19h 35m2 stops
Multiple Airlines Logo
11:35 pm - 11:56 pmVVI-CLE
25h 21m1 stop
$900Multiple Airlines
Find Deal
Wed, Nov 19 - Wed, Dec 3
Multiple Airlines Logo
6:38 pm - 2:35 amDTW-VVI
30h 57m3 stops
Multiple Airlines Logo
3:40 am - 8:23 pmVVI-DTW
17h 43m3 stops
$931Multiple Airlines
Find Deal
Wed, Dec 3 - Fri, Dec 5
Copa Airlines Logo
7:55 pm - 10:46 pmCLE-VVI
25h 51m2 stops
Copa Airlines Logo
1:09 am - 8:36 pmVVI-CLE
20h 27m2 stops
$1,001Copa Airlines
Find Deal
Fri, Dec 5 - Sun, Dec 14
Copa Airlines Logo
10:55 am - 3:36 amCLE-VVI
15h 41m2 stops
Copa Airlines Logo
11:40 am - 9:46 amVVI-CLE
23h 06m2 stops
$1,070Copa Airlines
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Fri, Dec 5 - Mon, Dec 15
LATAM Airlines Logo
7:00 am - 4:35 amCLE-VVI
21h 35m2 stops
LATAM Airlines Logo
8:27 am - 5:13 pmVVI-CLE
32h 46m2 stops
$1,279LATAM Airlines
Find Deal
Sun, Apr 5 - Wed, Apr 8

Copa Airlines flights from Ohio to Santa Cruz de la Sierra

Our best Copa Airlines deals on Ohio to Santa Cruz de la Sierra flight tickets
Copa Airlines
Nov 8
CLE7:50 pmCleveland Hopkins Intl
25h 56m
2 stops
VVI10:46 pmSanta Cruz de la Sierra Viru Viru Intl
Nov 10
VVI11:40 amSanta Cruz de la Sierra Viru Viru Intl
22h 55m
2 stops
CLE9:35 amCleveland Hopkins Intl
$932
Find similar
Copa Airlines
Dec 5
CLE7:55 pmCleveland Hopkins Intl
25h 51m
2 stops
VVI10:46 pmSanta Cruz de la Sierra Viru Viru Intl
Dec 14
VVI1:09 amSanta Cruz de la Sierra Viru Viru Intl
20h 27m
2 stops
CLE8:36 pmCleveland Hopkins Intl
$1,001
Find similar
Copa Airlines
Dec 5
CLE10:55 amCleveland Hopkins Intl
15h 41m
2 stops
VVI3:36 amSanta Cruz de la Sierra Viru Viru Intl
Dec 15
VVI11:40 amSanta Cruz de la Sierra Viru Viru Intl
23h 06m
2 stops
CLE9:46 amCleveland Hopkins Intl
$1,070
Find similar

United Airlines flights from Ohio to Santa Cruz de la Sierra

Our best United Airlines deals on Ohio to Santa Cruz de la Sierra flight tickets
United Airlines
Apr 5
CVG6:30 amCincinnati Cinci./N. Kentucky
16h 20m
2 stops
VVI10:50 pmSanta Cruz de la Sierra Viru Viru Intl
Apr 7
VVI11:44 amSanta Cruz de la Sierra Viru Viru Intl
35h 55m
2 stops
CVG11:39 pmCincinnati Cinci./N. Kentucky
$752
Find similar
United Airlines
Apr 5
CLE6:15 amCleveland Hopkins Intl
21h 29m
2 stops
VVI3:44 amSanta Cruz de la Sierra Viru Viru Intl
Apr 7
VVI11:44 amSanta Cruz de la Sierra Viru Viru Intl
30h 52m
2 stops
CLE6:36 pmCleveland Hopkins Intl
$772
Find similar
United Airlines
Mar 20
DAY9:00 amDayton
37h 50m
2 stops
VVI10:50 pmSanta Cruz de la Sierra Viru Viru Intl
Mar 24
VVI11:42 amSanta Cruz de la Sierra Viru Viru Intl
25h 42m
2 stops
DAY1:24 pmDayton
$828
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Ohio to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Ohio to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Wed 12/3

7:10 am-2:35 am

2 stops18h 25m

Santa Cruz de la Sierra Viru Viru Intl

Fri 12/5

3:40 am-5:53 pm

2 stops15h 13m

$713

CincinnatiSanta Cruz de la Sierra

CVG - VVI

CVGVVI

Cincinnati Cinci./N. Kentucky

Sun 4/5

6:30 am-10:50 pm

2 stops16h 20m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/7

11:44 am-11:39 pm

2 stops35h 55m

$752

ClevelandSanta Cruz de la Sierra

CLE - VVI

CLEVVI

Cleveland Hopkins Intl

Sun 4/5

6:15 am-3:44 am

2 stops21h 29m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/7

11:44 am-6:36 pm

2 stops30h 52m

$772

DaytonSanta Cruz de la Sierra

DAY - VVI

DAYVVI

Dayton

Fri 3/20

9:00 am-10:50 pm

2 stops37h 50m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/24

11:42 am-1:24 pm

2 stops25h 42m

$828

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Wed 12/3

7:10 am-2:35 am

2 stops18h 25m

Santa Cruz de la Sierra Viru Viru Intl

Fri 12/5

3:40 am-8:23 pm

3 stops17h 43m

$840

ClevelandSanta Cruz de la Sierra

CLE - VVI

CLEVVI

Cleveland Hopkins Intl

Wed 11/19

6:00 am-2:35 am

2 stops19h 35m

Santa Cruz de la Sierra Viru Viru Intl

Wed 12/3

11:35 pm-11:56 pm

1 stop25h 21m

$900

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Wed 12/3

6:38 pm-2:35 am

3 stops30h 57m

Santa Cruz de la Sierra Viru Viru Intl

Fri 12/5

3:40 am-8:23 pm

3 stops17h 43m

$931

ClevelandSanta Cruz de la Sierra

CLE - VVI

CLEVVI

Cleveland Hopkins Intl

Fri 12/5

7:55 pm-10:46 pm

2 stops25h 51m

Santa Cruz de la Sierra Viru Viru Intl

Sun 12/14

1:09 am-8:36 pm

2 stops20h 27m

$1,001

ClevelandSanta Cruz de la Sierra

CLE - VVI

CLEVVI

Cleveland Hopkins Intl

Fri 12/5

10:55 am-3:36 am

2 stops15h 41m

Santa Cruz de la Sierra Viru Viru Intl

Mon 12/15

11:40 am-9:46 am

2 stops23h 06m

$1,070

ClevelandSanta Cruz de la Sierra

CLE - VVI

CLEVVI

Cleveland Hopkins Intl

Sun 4/5

7:00 am-4:35 am

2 stops21h 35m

Santa Cruz de la Sierra Viru Viru Intl

Wed 4/8

8:27 am-5:13 pm

2 stops32h 46m

$1,279

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Ohio to Santa Cruz de la Sierra

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

How long does it take to fly to Santa Cruz de la Sierra?

If you’re flying from a popular airport in Ohio, such as Cincinnati or Cleveland, and flying into Santa Cruz de la Sierra, then you can expect flight times to average 15h 54m and 19h 35m, respectively.

Cheap Ohio to Santa Cruz de la Sierra flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Ohio to Santa Cruz de la Sierra

Direct flights

None
There are no direct flights from Ohio to Santa Cruz de la Sierra. There are no popular flight routes from Ohio to Santa Cruz de la Sierra.
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  • When did momondo last update prices for flights from Ohio to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from Ohio to Santa Cruz de la Sierra Viru Viru Intl Airport were last updated today.

  • How old do you have to be to fly from Ohio to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Ohio to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The required travel and health documents for your Santa Cruz de la Sierra Viru Viru Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Cruz de la Sierra Viru Viru Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Ohio to Santa Cruz de la Sierra?

It is quick and easy to find Ohio to Santa Cruz de la Sierra flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santa Cruz de la Sierra that suits you.

Can I find flights from Ohio to Santa Cruz de la Sierra with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Ohio to Santa Cruz de la Sierra flights to just show those with flexible booking policies.

How can momondo help me find flights from Ohio to Santa Cruz de la Sierra?

Once you have performed a search for Ohio to Santa Cruz de la Sierra flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Ohio to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

Price alerts on flights to Santa Cruz de la Sierra from Ohio are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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