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Cheap flights from Ohio to Santa Cruz de la Sierra from $505

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Ohio to Santa Cruz de la Sierra departing on 12/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Ohio to Santa Cruz de la Sierra

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:07 pm - 5:00 pmCLE  Cleveland Hopkins Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
23h 53m1 stop Miami
Multiple Airlines Logo
11:35 pm - 12:26 amVVI  Santa Cruz de la Sierra Viru Viru Intl-CLE Cleveland Hopkins Intl
24h 51m1 stop Miami
$890Multiple Airlines
Sun, Aug 30 - Sun, Sep 6
Multiple Airlines Logo
5:15 pm - 5:00 pmCLE  Cleveland Hopkins Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
23h 45m2 stops Atlanta Hartsfield-Jackson Miami
Multiple Airlines Logo
11:35 pm - 12:26 amVVI  Santa Cruz de la Sierra Viru Viru Intl-CLE Cleveland Hopkins Intl
24h 51m1 stop Miami
$925Multiple Airlines
Sun, Aug 30 - Sun, Sep 6
United Airlines Logo
5:55 pm - 3:37 amCLE  Cleveland Hopkins Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
32h 42m2 stops Chicago O'Hare Intl Panama City Tocumen Intl
United Airlines Logo
11:49 am - 9:38 amVVI  Santa Cruz de la Sierra Viru Viru Intl-CLE Cleveland Hopkins Intl
22h 49m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl
$930United Airlines
Sun, Nov 15 - Sat, Nov 21
Copa Airlines Logo
5:45 am - 10:38 pmDTW  Detroit Metropolitan Wayne County-VVI Santa Cruz de la Sierra Viru Viru Intl
15h 53m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl
Copa Airlines Logo
11:49 am - 8:30 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-DTW Detroit Metropolitan Wayne County
33h 41m2 stops Panama City Tocumen Intl Chicago O'Hare Intl
$943Copa Airlines
Thu, Nov 5 - Tue, Nov 10
Multiple Airlines Logo
6:00 am - 10:40 pmDTW  Detroit Metropolitan Wayne County-VVI Santa Cruz de la Sierra Viru Viru Intl
40h 40m3 stops Atlanta Hartsfield-Jackson Fort Lauderdale Panama City Tocumen Intl
Multiple Airlines Logo
1:12 am - 7:24 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-DTW Detroit Metropolitan Wayne County
42h 12m3 stops Panama City Tocumen Intl Fort Lauderdale Raleigh-Durham
$964Multiple Airlines
Sun, Aug 23 - Wed, Aug 26
United Airlines Logo
7:00 am - 10:44 pmDTW  Detroit Metropolitan Wayne County-VVI Santa Cruz de la Sierra Viru Viru Intl
39h 44m2 stops Newark Panama City Tocumen Intl
United Airlines Logo
11:47 am - 10:00 amVVI  Santa Cruz de la Sierra Viru Viru Intl-DTW Detroit Metropolitan Wayne County
22h 13m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl
$988United Airlines
Sat, Oct 3 - Tue, Oct 6
United Airlines Logo
6:27 pm - 10:38 pmDTW  Detroit Metropolitan Wayne County-VVI Santa Cruz de la Sierra Viru Viru Intl
51h 11m2 stops Chicago O'Hare Intl Panama City Tocumen Intl
United Airlines Logo
11:49 am - 11:59 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-DTW Detroit Metropolitan Wayne County
37h 10m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl
$995United Airlines
Sun, Nov 15 - Sat, Nov 21
Copa Airlines Logo
7:54 pm - 10:40 pmCLE  Cleveland Hopkins Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
26h 46m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl
Copa Airlines Logo
1:12 am - 11:16 amVVI  Santa Cruz de la Sierra Viru Viru Intl-CLE Cleveland Hopkins Intl
34h 04m2 stops Panama City Tocumen Intl Chicago O'Hare Intl
$1,003Copa Airlines
Sun, Aug 30 - Sat, Sep 5
Copa Airlines Logo
10:55 am - 10:44 pmDTW  Detroit Metropolitan Wayne County-VVI Santa Cruz de la Sierra Viru Viru Intl
35h 49m2 stops Chicago O'Hare Intl Panama City Tocumen Intl
Copa Airlines Logo
1:12 am - 8:25 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-DTW Detroit Metropolitan Wayne County
19h 13m2 stops Panama City Tocumen Intl Chicago O'Hare Intl
$1,026Copa Airlines
Sat, Sep 5 - Fri, Sep 11
United Airlines Logo
10:20 am - 10:44 pmDTW  Detroit Metropolitan Wayne County-VVI Santa Cruz de la Sierra Viru Viru Intl
36h 24m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl
United Airlines Logo
11:47 am - 11:27 amVVI  Santa Cruz de la Sierra Viru Viru Intl-DTW Detroit Metropolitan Wayne County
47h 40m3 stops Panama City Tocumen Intl Houston George Bush Intcntl Chicago O'Hare Intl
$1,066United Airlines
Sat, Sep 5 - Sat, Sep 12

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Avianca flights from Ohio to Santa Cruz de la Sierra

Our best Avianca deals on Ohio to Santa Cruz de la Sierra flight tickets
Avianca
Nov 16
CLE10:34 amCleveland Hopkins Intl
15h 01m
2 stops
VVI2:35 amSanta Cruz de la Sierra Viru Viru Intl
Nov 19
VVI3:40 amSanta Cruz de la Sierra Viru Viru Intl
17h 09m
2 stops
CLE7:49 pmCleveland Hopkins Intl
$1,351
Avianca
Oct 19
DTW6:00 amDetroit Metropolitan Wayne County
20h 30m
2 stops
VVI2:30 amSanta Cruz de la Sierra Viru Viru Intl
Oct 20
VVI3:35 amSanta Cruz de la Sierra Viru Viru Intl
30h 25m
2 stops
DTW10:00 amDetroit Metropolitan Wayne County
$1,381

United Airlines flights from Ohio to Santa Cruz de la Sierra

Our best United Airlines deals on Ohio to Santa Cruz de la Sierra flight tickets
United Airlines
Nov 15
CLE5:55 pmCleveland Hopkins Intl
32h 42m
2 stops
VVI3:37 amSanta Cruz de la Sierra Viru Viru Intl
Nov 21
VVI11:49 amSanta Cruz de la Sierra Viru Viru Intl
22h 49m
2 stops
CLE9:38 amCleveland Hopkins Intl
$930
United Airlines
Oct 3
DTW7:00 amDetroit Metropolitan Wayne County
39h 44m
2 stops
VVI10:44 pmSanta Cruz de la Sierra Viru Viru Intl
Oct 6
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
22h 13m
2 stops
DTW10:00 amDetroit Metropolitan Wayne County
$988
United Airlines
Nov 15
DTW6:27 pmDetroit Metropolitan Wayne County
51h 11m
2 stops
VVI10:38 pmSanta Cruz de la Sierra Viru Viru Intl
Nov 21
VVI11:49 amSanta Cruz de la Sierra Viru Viru Intl
37h 10m
2 stops
DTW11:59 pmDetroit Metropolitan Wayne County
$995

momondo Fare Finder

 
Customize your flight search to find flights from Ohio to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 9, 2026.
Use the filters below to find and compare flights from Ohio to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ClevelandSanta Cruz de la Sierra

CLE Cleveland Hopkins Intl - VVI Santa Cruz de la Sierra Viru Viru Intl

CLEVVI

Cleveland Hopkins Intl

Sun 8/30

5:07 pm-5:00 pm

1 stop23h 53m

Santa Cruz de la Sierra Viru Viru Intl

Sun 9/6

11:35 pm-12:26 am

1 stop24h 51m

$890
Quickest round-trip

ClevelandSanta Cruz de la Sierra

CLE Cleveland Hopkins Intl - VVI Santa Cruz de la Sierra Viru Viru Intl

CLEVVI

Cleveland Hopkins Intl

Sun 8/30

5:15 pm-5:00 pm

2 stops23h 45m

Santa Cruz de la Sierra Viru Viru Intl

Sun 9/6

11:35 pm-12:26 am

1 stop24h 51m

$925

ClevelandSanta Cruz de la Sierra

CLE Cleveland Hopkins Intl - VVI Santa Cruz de la Sierra Viru Viru Intl

CLEVVI

Cleveland Hopkins Intl

Sun 11/15

5:55 pm-3:37 am

2 stops32h 42m

Santa Cruz de la Sierra Viru Viru Intl

Sat 11/21

11:49 am-9:38 am

2 stops22h 49m

$930

DetroitSanta Cruz de la Sierra

DTW Detroit Metropolitan Wayne County - VVI Santa Cruz de la Sierra Viru Viru Intl

DTWVVI

Detroit Metropolitan Wayne County

Thu 11/5

5:45 am-10:38 pm

2 stops15h 53m

Santa Cruz de la Sierra Viru Viru Intl

Tue 11/10

11:49 am-8:30 pm

2 stops33h 41m

$943

DetroitSanta Cruz de la Sierra

DTW Detroit Metropolitan Wayne County - VVI Santa Cruz de la Sierra Viru Viru Intl

DTWVVI

Detroit Metropolitan Wayne County

Sun 8/23

6:00 am-10:40 pm

3 stops40h 40m

Santa Cruz de la Sierra Viru Viru Intl

Wed 8/26

1:12 am-7:24 pm

3 stops42h 12m

$964

DetroitSanta Cruz de la Sierra

DTW Detroit Metropolitan Wayne County - VVI Santa Cruz de la Sierra Viru Viru Intl

DTWVVI

Detroit Metropolitan Wayne County

Sat 10/3

7:00 am-10:44 pm

2 stops39h 44m

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/6

11:47 am-10:00 am

2 stops22h 13m

$988

DetroitSanta Cruz de la Sierra

DTW Detroit Metropolitan Wayne County - VVI Santa Cruz de la Sierra Viru Viru Intl

DTWVVI

Detroit Metropolitan Wayne County

Sun 11/15

6:27 pm-10:38 pm

2 stops51h 11m

Santa Cruz de la Sierra Viru Viru Intl

Sat 11/21

11:49 am-11:59 pm

2 stops37h 10m

$995

ClevelandSanta Cruz de la Sierra

CLE Cleveland Hopkins Intl - VVI Santa Cruz de la Sierra Viru Viru Intl

CLEVVI

Cleveland Hopkins Intl

Sun 8/30

7:54 pm-10:40 pm

2 stops26h 46m

Santa Cruz de la Sierra Viru Viru Intl

Sat 9/5

1:12 am-11:16 am

2 stops34h 04m

$1,003

DetroitSanta Cruz de la Sierra

DTW Detroit Metropolitan Wayne County - VVI Santa Cruz de la Sierra Viru Viru Intl

DTWVVI

Detroit Metropolitan Wayne County

Sat 9/5

10:55 am-10:44 pm

2 stops35h 49m

Santa Cruz de la Sierra Viru Viru Intl

Fri 9/11

1:12 am-8:25 pm

2 stops19h 13m

$1,026

DetroitSanta Cruz de la Sierra

DTW Detroit Metropolitan Wayne County - VVI Santa Cruz de la Sierra Viru Viru Intl

DTWVVI

Detroit Metropolitan Wayne County

Sat 9/5

10:20 am-10:44 pm

2 stops36h 24m

Santa Cruz de la Sierra Viru Viru Intl

Sat 9/12

11:47 am-11:27 am

3 stops47h 40m

$1,066

Flights are sorted by cheapest round-trip flights first.

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How to get the cheapest flight ticket from Ohio to Santa Cruz de la Sierra

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Ohio to Santa Cruz de la Sierra Viru Viru Intl?

United Airlines is the most popular carrier operating from Ohio to Santa Cruz de la Sierra Viru Viru Intl

Cheap Ohio to Santa Cruz de la Sierra flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Ohio to Santa Cruz de la Sierra

Fastest flight time

15h 53m

Direct flights

None
The fastest flight from Ohio to Santa Cruz de la Sierra takes 15h 53m
There are no direct flights from Ohio to Santa Cruz de la Sierra. There are no popular flight routes from Ohio to Santa Cruz de la Sierra.
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Frequently asked questions about flying from Ohio to Santa Cruz de la Sierra

  • When did momondo last update prices for flights from Ohio to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from Ohio to Santa Cruz de la Sierra Viru Viru Intl Airport were last updated today.

  • How old do you have to be to fly from Ohio to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Ohio to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The required travel and health documents for your Santa Cruz de la Sierra Viru Viru Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Cruz de la Sierra Viru Viru Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Ohio to Santa Cruz de la Sierra?

It is quick and easy to find Ohio to Santa Cruz de la Sierra flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santa Cruz de la Sierra that suits you.

Can I find flights from Ohio to Santa Cruz de la Sierra with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Ohio to Santa Cruz de la Sierra flights to just show those with flexible booking policies.

How can momondo help me find flights from Ohio to Santa Cruz de la Sierra?

Once you have performed a search for Ohio to Santa Cruz de la Sierra flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Ohio to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

Price alerts on flights to Santa Cruz de la Sierra from Ohio are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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