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Cheap flights from Chicago O'Hare Intl Airport to Santiago from $285

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Santiago departing on 9/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago O'Hare Intl Airport to Santiago

Cheap round-trip flights

Logo
10:27 am - 11:20 amORD-SCL
22h 53m2 stops
Logo
11:00 am - 9:22 amSCL-ORD
24h 22m1 stop
$611
Find Deal
Fri, Sep 26 - Wed, Oct 8
Logo
10:27 am - 3:35 amORD-SCL
39h 08m2 stops
Logo
11:00 am - 9:18 amSCL-ORD
24h 18m1 stop
$622
Find Deal
Wed, Sep 10 - Mon, Sep 22
Logo
10:27 am - 3:35 amORD-SCL
39h 08m2 stops
Logo
11:00 am - 9:18 amSCL-ORD
24h 18m1 stop
$623
Find Deal
Mon, Sep 8 - Mon, Sep 22
Logo
10:27 am - 3:35 amORD-SCL
39h 08m2 stops
Logo
11:00 am - 9:22 amSCL-ORD
24h 22m1 stop
$628
Find Deal
Wed, Oct 1 - Wed, Oct 8
LATAM Airlines Logo
11:20 am - 5:45 amORD-SCL
16h 25m2 stops
LATAM Airlines Logo
1:10 pm - 12:24 pmSCL-ORD
25h 14m2 stops
$691LATAM Airlines
Find Deal
Sun, Sep 14 - Sat, Sep 20
Avianca Logo
11:20 pm - 3:20 pmORD-SCL
14h 00m1 stop
Avianca Logo
1:35 am - 8:20 pmSCL-ORD
21h 45m1 stop
$719Avianca
Find Deal
Fri, Oct 31 - Sun, Nov 9
Avianca Logo
2:35 pm - 2:25 pmORD-SCL
21h 50m1 stop
Avianca Logo
12:55 am - 1:15 pmSCL-ORD
14h 20m1 stop
$724Avianca
Find Deal
Tue, Sep 16 - Sun, Sep 21
Avianca Logo
2:35 pm - 5:15 amORD-SCL
12h 40m1 stop
Avianca Logo
12:55 am - 1:15 pmSCL-ORD
14h 20m1 stop
$730Avianca
Find Deal
Sun, Sep 14 - Sat, Sep 20
Avianca Logo
2:35 pm - 5:15 amORD-SCL
12h 40m1 stop
Avianca Logo
7:35 am - 9:20 pmSCL-ORD
15h 45m1 stop
$731Avianca
Find Deal
Tue, Oct 14 - Fri, Oct 31
LATAM Airlines Logo
10:40 am - 6:55 amORD-SCL
17h 15m1 stop
LATAM Airlines Logo
11:40 pm - 5:37 pmSCL-ORD
20h 57m1 stop
$744LATAM Airlines
Find Deal
Tue, Jan 27 - Tue, Feb 10

Avianca flights from Chicago O'Hare Intl Airport to Santiago

Our best Avianca deals on Chicago O'Hare Intl Airport to Santiago flight tickets
Avianca
Oct 31
ORD11:20 pmChicago O'Hare Intl
14h 00m
1 stop
SCL3:20 pmSantiago Arturo Merino Benitez
Nov 9
SCL1:35 amSantiago Arturo Merino Benitez
21h 45m
1 stop
ORD8:20 pmChicago O'Hare Intl
$719
Find similar
Avianca
Sep 1
ORD2:35 pmChicago O'Hare Intl
21h 50m
1 stop
SCL1:25 pmSantiago Arturo Merino Benitez
Sep 23
SCL12:55 amSantiago Arturo Merino Benitez
14h 20m
1 stop
ORD1:15 pmChicago O'Hare Intl
$724
Find similar
Avianca
Sep 14
ORD2:35 pmChicago O'Hare Intl
12h 40m
1 stop
SCL5:15 amSantiago Arturo Merino Benitez
Sep 20
SCL12:55 amSantiago Arturo Merino Benitez
14h 20m
1 stop
ORD1:15 pmChicago O'Hare Intl
$730
Find similar

Copa Airlines flights from Chicago O'Hare Intl Airport to Santiago

Our best Copa Airlines deals on Chicago O'Hare Intl Airport to Santiago flight tickets
Copa Airlines
Sep 1
ORD8:02 amChicago O'Hare Intl
17h 40m
1 stop
SCL2:42 amSantiago Arturo Merino Benitez
Sep 3
SCL2:26 amSantiago Arturo Merino Benitez
22h 55m
1 stop
ORD12:21 amChicago O'Hare Intl
$872
Find similar
Copa Airlines
Aug 31
ORD7:55 amChicago O'Hare Intl
17h 47m
1 stop
SCL2:42 amSantiago Arturo Merino Benitez
Sep 4
SCL2:26 amSantiago Arturo Merino Benitez
22h 55m
1 stop
ORD12:21 amChicago O'Hare Intl
$892
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Fri 9/26

10:27 am-11:20 am

2 stops22h 53m

Santiago Arturo Merino Benitez

Wed 10/8

11:00 am-9:22 am

1 stop24h 22m

$611

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Wed 9/10

10:27 am-3:35 am

2 stops39h 08m

Santiago Arturo Merino Benitez

Mon 9/22

11:00 am-9:18 am

1 stop24h 18m

$622

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 9/8

10:27 am-3:35 am

2 stops39h 08m

Santiago Arturo Merino Benitez

Mon 9/22

11:00 am-9:18 am

1 stop24h 18m

$623

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Wed 10/1

10:27 am-3:35 am

2 stops39h 08m

Santiago Arturo Merino Benitez

Wed 10/8

11:00 am-9:22 am

1 stop24h 22m

$628

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 9/14

11:20 am-5:45 am

2 stops16h 25m

Santiago Arturo Merino Benitez

Sat 9/20

1:10 pm-12:24 pm

2 stops25h 14m

$691

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Fri 10/31

11:20 pm-3:20 pm

1 stop14h 00m

Santiago Arturo Merino Benitez

Sun 11/9

1:35 am-8:20 pm

1 stop21h 45m

$719

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Tue 9/16

2:35 pm-2:25 pm

1 stop21h 50m

Santiago Arturo Merino Benitez

Sun 9/21

12:55 am-1:15 pm

1 stop14h 20m

$724

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 9/14

2:35 pm-5:15 am

1 stop12h 40m

Santiago Arturo Merino Benitez

Sat 9/20

12:55 am-1:15 pm

1 stop14h 20m

$730

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Tue 10/14

2:35 pm-5:15 am

1 stop12h 40m

Santiago Arturo Merino Benitez

Fri 10/31

7:35 am-9:20 pm

1 stop15h 45m

$731

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Tue 1/27

10:40 am-6:55 am

1 stop17h 15m

Santiago Arturo Merino Benitez

Tue 2/10

11:40 pm-5:37 pm

1 stop20h 57m

$744

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, May is the cheapest month to fly from Chicago O'Hare Intl Airport to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $665. If you don’t want to visit Santiago in May, then you should wait until April to fly from Chicago O'Hare Intl Airport, when ticket prices are also cheap, with an average price of $690.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $847. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $992.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Chicago O'Hare Intl Airport to Santiago when you can find flight prices for as low as $843. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $942 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $855 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Chicago O'Hare Intl Airport for as low as $716 on momondo.

How have Chicago O'Hare Intl Airport to Santiago flight prices changed over time?

As of August 2025, prices for Chicago O'Hare Intl Airport to Santiago flights are approximately 32% cheaper when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Santiago (ORD to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Santiago

Best Price Found

$285

Fastest flight time

12h 40m

Direct flights

None

Airports in Santiago

1 airport
The best one-way flight to Santiago from Chicago O'Hare Intl Airport in the past 72 hours is $285. The best round-trip flight deal from Chicago O'Hare Intl Airport to Santiago found on momondo in the last 72 hours is $611.
The fastest flight from Chicago O'Hare Intl Airport to Santiago takes 12h 40m
There are no direct flights from Chicago O'Hare Intl Airport to Santiago. Popular non-direct route for this connection is Chicago O'Hare Intl Airport - Santiago Arturo Merino Benitez Airport.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)
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  • How far is Chicago O'Hare Intl to Santiago Arturo Merino Benitez by plane?

    Santiago Arturo Merino Benitez is 5321.5 mi away from Chicago O'Hare Intl. 12h 40m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago O'Hare Intl Airport to Santiago?

Best airlines flying from Chicago O'Hare Intl Airport to Santiago

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Santiago with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $511Free CancellationRating
7.5
1,510 reviews
Search Copa Airlines flights
AviancaPriceFrom $539Free CancellationRating
6.7
2,407 reviews
Search Avianca flights
LATAM AirlinesPriceFrom $694Free CancellationRating
7.5
1,844 reviews
Search LATAM Airlines flights
DeltaPriceFrom $698Free CancellationRating
8.0
7,981 reviews
Search Delta flights
Air CanadaPriceFrom $707Free CancellationRating
7.1
9,992 reviews
Search Air Canada flights
American AirlinesPriceFrom $750Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $782Free CancellationRating
7.4
8,925 reviews
Search United Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Santiago with flexible booking policies on momondo?

All flight searches from Chicago to Santiago on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Chicago to Santiago?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santiago from Chicago.

I’m not ready to book a flight from Chicago to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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