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Cheap flights from Chicago O'Hare Intl Airport to Santiago from $253

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Santiago departing on 1/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago O'Hare Intl Airport to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
1:11 am - 7:30 amORD-SCL
27h 19m1 stop
Multiple Airlines Logo
9:10 am - 12:55 pmSCL-ORD
30h 45m1 stop
$689Multiple Airlines
Find Deal
Thu, Feb 26 - Sun, Mar 1
Air Canada Logo
10:35 am - 12:15 pmORD-SCL
22h 40m2 stops
Air Canada Logo
8:55 pm - 2:55 pmSCL-ORD
21h 00m2 stops
$691Air Canada
Find Deal
Mon, Feb 2 - Tue, Feb 17
Multiple Airlines Logo
7:35 am - 11:43 pmORD-SCL
13h 08m1 stop
Multiple Airlines Logo
10:15 pm - 8:18 amSCL-ORD
37h 03m2 stops
$692Multiple Airlines
Find Deal
Mon, Jan 12 - Mon, Jan 19
Multiple Airlines Logo
7:35 am - 11:43 pmORD-SCL
13h 08m1 stop
Multiple Airlines Logo
6:40 am - 11:46 pmSCL-ORD
44h 06m2 stops
$693Multiple Airlines
Find Deal
Mon, Jan 12 - Mon, Jan 19
LATAM Airlines Logo
2:50 pm - 7:40 amORD-SCL
13h 50m1 stop
LATAM Airlines Logo
12:20 am - 4:49 pmSCL-ORD
19h 29m2 stops
$694LATAM Airlines
Find Deal
Mon, Feb 2 - Mon, Feb 16
LATAM Airlines Logo
10:36 am - 6:55 amORD-SCL
17h 19m1 stop
LATAM Airlines Logo
11:30 pm - 1:29 pmSCL-ORD
16h 59m1 stop
$698LATAM Airlines
Find Deal
Fri, Feb 27 - Sun, Mar 1
Avianca Logo
10:20 pm - 3:20 pmORD-SCL
14h 00m1 stop
Avianca Logo
1:35 am - 8:20 pmSCL-ORD
21h 45m1 stop
$701Avianca
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Thu, Jan 15 - Tue, Jan 27
Multiple Airlines Logo
9:23 am - 2:40 pmORD-SCL
26h 17m2 stops
Multiple Airlines Logo
1:35 am - 12:18 amSCL-ORD
25h 43m3 stops
$702Multiple Airlines
Find Deal
Sun, Feb 8 - Sat, Feb 21
Multiple Airlines Logo
8:00 am - 10:39 amORD-SCL
23h 39m3 stops
Multiple Airlines Logo
12:40 am - 6:16 pmSCL-ORD
20h 36m2 stops
$703Multiple Airlines
Find Deal
Sat, Jan 24 - Fri, Feb 6
LATAM Airlines Logo
10:40 am - 7:00 amORD-SCL
18h 20m2 stops
LATAM Airlines Logo
10:55 pm - 5:10 pmSCL-ORD
19h 15m1 stop
$706LATAM Airlines
Find Deal
Thu, Mar 26 - Sun, Apr 5

Air Canada flights from Chicago O'Hare Intl Airport to Santiago

Our best Air Canada deals on Chicago O'Hare Intl Airport to Santiago flight tickets
Air Canada
Feb 2
ORD10:35 amChicago O'Hare Intl
22h 40m
2 stops
SCL12:15 pmSantiago Arturo Merino Benitez
Feb 17
SCL8:55 pmSantiago Arturo Merino Benitez
21h 00m
2 stops
ORD2:55 pmChicago O'Hare Intl
$691
Find similar
Air Canada
Mar 15
ORD2:00 pmChicago O'Hare Intl
19h 15m
1 stop
SCL11:15 amSantiago Arturo Merino Benitez
Mar 26
SCL7:55 pmSantiago Arturo Merino Benitez
19h 06m
1 stop
ORD1:01 pmChicago O'Hare Intl
$733
Find similar
Air Canada
Mar 15
ORD10:35 amChicago O'Hare Intl
46h 40m
2 stops
SCL11:15 amSantiago Arturo Merino Benitez
Mar 26
SCL7:55 pmSantiago Arturo Merino Benitez
21h 00m
2 stops
ORD2:55 pmChicago O'Hare Intl
$738
Find similar

LATAM Airlines flights from Chicago O'Hare Intl Airport to Santiago

Our best LATAM Airlines deals on Chicago O'Hare Intl Airport to Santiago flight tickets
LATAM Airlines
Feb 2
ORD2:50 pmChicago O'Hare Intl
13h 50m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Feb 16
SCL12:20 amSantiago Arturo Merino Benitez
19h 29m
2 stops
ORD4:49 pmChicago O'Hare Intl
$694
Find similar
LATAM Airlines
Feb 27
ORD10:36 amChicago O'Hare Intl
17h 19m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
Mar 1
SCL11:30 pmSantiago Arturo Merino Benitez
16h 59m
1 stop
ORD1:29 pmChicago O'Hare Intl
$698
Find similar
LATAM Airlines
Mar 26
ORD10:40 amChicago O'Hare Intl
18h 20m
2 stops
SCL7:00 amSantiago Arturo Merino Benitez
Apr 5
SCL10:55 pmSantiago Arturo Merino Benitez
19h 15m
1 stop
ORD5:10 pmChicago O'Hare Intl
$706
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 30, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Thu 2/26

1:11 am-7:30 am

1 stop27h 19m

Santiago Arturo Merino Benitez

Sun 3/1

9:10 am-12:55 pm

1 stop30h 45m

$689

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 2/2

10:35 am-12:15 pm

2 stops22h 40m

Santiago Arturo Merino Benitez

Tue 2/17

8:55 pm-2:55 pm

2 stops21h 00m

$691

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 1/12

7:35 am-11:43 pm

1 stop13h 08m

Santiago Arturo Merino Benitez

Mon 1/19

10:15 pm-8:18 am

2 stops37h 03m

$692

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 1/12

7:35 am-11:43 pm

1 stop13h 08m

Santiago Arturo Merino Benitez

Mon 1/19

6:40 am-11:46 pm

2 stops44h 06m

$693

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 2/2

2:50 pm-7:40 am

1 stop13h 50m

Santiago Arturo Merino Benitez

Mon 2/16

12:20 am-4:49 pm

2 stops19h 29m

$694

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Fri 2/27

10:36 am-6:55 am

1 stop17h 19m

Santiago Arturo Merino Benitez

Sun 3/1

11:30 pm-1:29 pm

1 stop16h 59m

$698

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Thu 1/15

10:20 pm-3:20 pm

1 stop14h 00m

Santiago Arturo Merino Benitez

Tue 1/27

1:35 am-8:20 pm

1 stop21h 45m

$701

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 2/8

9:23 am-2:40 pm

2 stops26h 17m

Santiago Arturo Merino Benitez

Sat 2/21

1:35 am-12:18 am

3 stops25h 43m

$702

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sat 1/24

8:00 am-10:39 am

3 stops23h 39m

Santiago Arturo Merino Benitez

Fri 2/6

12:40 am-6:16 pm

2 stops20h 36m

$703

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Thu 3/26

10:40 am-7:00 am

2 stops18h 20m

Santiago Arturo Merino Benitez

Sun 4/5

10:55 pm-5:10 pm

1 stop19h 15m

$706

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, May is the cheapest month to fly from Chicago O'Hare Intl Airport to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $665. If you don’t want to visit Santiago in May, then you should wait until April to fly from Chicago O'Hare Intl Airport, when ticket prices are also cheap, with an average price of $722.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $847. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $992.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Chicago O'Hare Intl Airport to Santiago when you can find flight prices for as low as $843. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $942 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $854 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Chicago O'Hare Intl Airport for as low as $673 on momondo.

How have Chicago O'Hare Intl Airport to Santiago flight prices changed over time?

As of November 2025, prices for Chicago O'Hare Intl Airport to Santiago flights are approximately 34% cheaper when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Santiago (ORD to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Santiago

Fastest flight time

14h 00m

Direct flights

None
The fastest flight from Chicago O'Hare Intl Airport to Santiago takes 14h 00m
There are no direct flights from Chicago O'Hare Intl Airport to Santiago. There are no popular flight routes from Chicago O'Hare Intl Airport to Santiago.
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  • How far is Chicago O'Hare Intl to Santiago Arturo Merino Benitez by plane?

    Santiago Arturo Merino Benitez is 5321.5 mi away from Chicago O'Hare Intl. 12h 40m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago O'Hare Intl Airport to Santiago?

Best airlines flying from Chicago O'Hare Intl Airport to Santiago

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Santiago with momondo
Airline
Rating
Free Cancellation
Price
Air CanadaPriceFrom $484Free CancellationRating
7.1
10,484 reviews
Search Air Canada flights
AviancaPriceFrom $564Free CancellationRating
6.6
2,474 reviews
Search Avianca flights
United AirlinesPriceFrom $626Free CancellationRating
7.4
9,057 reviews
Search United Airlines flights
DeltaPriceFrom $626Free CancellationRating
7.9
8,011 reviews
Search Delta flights
American AirlinesPriceFrom $639Free CancellationRating
7.2
11,043 reviews
Search American Airlines flights
Copa AirlinesPriceFrom $641Free CancellationRating
7.6
1,566 reviews
Search Copa Airlines flights
LATAM AirlinesPriceFrom $684Free CancellationRating
7.5
1,889 reviews
Search LATAM Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Santiago with flexible booking policies on momondo?

All flight searches from Chicago to Santiago on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Chicago to Santiago?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santiago from Chicago.

I’m not ready to book a flight from Chicago to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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