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Cheap flights from Chicago O'Hare Intl Airport to Santiago from $255

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Santiago departing on 3/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Chicago O'Hare Intl Airport to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
7:56 am - 12:34 am
ORD
-
SCL
14h 38m
1 stop
Copa Airlines Logo
4:17 am - 1:13 am
SCL
-
ORD
21h 56m
1 stop
$536Copa Airlines
Mon, Mar 30 - Wed, Apr 15
LATAM Airlines Logo
5:59 pm - 8:15 am
ORD
-
SCL
12h 16m
1 stop
LATAM Airlines Logo
7:15 am - 11:59 pm
SCL
-
ORD
17h 44m
2 stops
$573LATAM Airlines
Mon, Mar 30 - Wed, Apr 15
Delta Logo
1:57 pm - 8:15 am
ORD
-
SCL
16h 18m
2 stops
Delta Logo
7:45 am - 11:59 pm
SCL
-
ORD
17h 14m
2 stops
$578Delta
Mon, Mar 30 - Wed, Apr 15
LATAM Airlines Logo
6:00 am - 1:35 pm
ORD
-
SCL
30h 35m
2 stops
LATAM Airlines Logo
11:05 pm - 11:57 pm
SCL
-
ORD
25h 52m
2 stops
$597LATAM Airlines
Sat, Aug 1 - Sun, Aug 9
LATAM Airlines Logo
9:44 am - 6:00 am
ORD
-
SCL
19h 16m
2 stops
LATAM Airlines Logo
11:00 pm - 2:20 pm
SCL
-
ORD
16h 20m
2 stops
$602LATAM Airlines
Mon, Jun 1 - Mon, Jun 8
Copa Airlines Logo
8:02 am - 11:26 pm
ORD
-
SCL
14h 24m
1 stop
Copa Airlines Logo
12:01 am - 2:06 pm
SCL
-
ORD
15h 05m
1 stop
$605Copa Airlines
Mon, Jun 1 - Sun, Jun 7
Multiple Airlines Logo
7:17 am - 10:39 am
ORD
-
SCL
25h 22m
2 stops
Multiple Airlines Logo
11:24 am - 2:16 pm
SCL
-
ORD
28h 52m
3 stops
$611Multiple Airlines
Wed, Mar 18 - Wed, Mar 25
United Airlines Logo
6:20 pm - 7:50 am
ORD
-
SCL
35h 30m
1 stop
United Airlines Logo
9:45 pm - 11:59 pm
SCL
-
ORD
28h 14m
1 stop
$614United Airlines
Fri, Mar 13 - Sun, Mar 22
Multiple Airlines Logo
6:01 pm - 5:14 am
ORD
-
SCL
33h 13m
3 stops
Multiple Airlines Logo
11:24 am - 2:16 pm
SCL
-
ORD
28h 52m
3 stops
$616Multiple Airlines
Wed, Mar 18 - Wed, Mar 25
LATAM Airlines Logo
6:45 am - 7:40 am
ORD
-
SCL
21h 55m
1 stop
LATAM Airlines Logo
7:15 am - 4:50 pm
SCL
-
ORD
36h 35m
3 stops
$617LATAM Airlines
Mon, Feb 16 - Sun, Feb 22

United Airlines flights from Chicago O'Hare Intl Airport to Santiago

Our best United Airlines deals on Chicago O'Hare Intl Airport to Santiago flight tickets
United Airlines
Mar 20
ORD9:15 pmChicago O'Hare Intl
32h 35m
1 stop
SCL7:50 amSantiago Arturo Merino Benitez
Mar 27
SCL9:45 pmSantiago Arturo Merino Benitez
15h 25m
1 stop
ORD11:10 amChicago O'Hare Intl
$710
United Airlines
Feb 24
ORD9:15 pmChicago O'Hare Intl
32h 35m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Mar 5
SCL10:45 pmSantiago Arturo Merino Benitez
15h 25m
1 stop
ORD11:10 amChicago O'Hare Intl
$712
United Airlines
Feb 14
ORD7:35 amChicago O'Hare Intl
22h 15m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Feb 25
SCL10:45 pmSantiago Arturo Merino Benitez
14h 22m
1 stop
ORD10:07 amChicago O'Hare Intl
$760

LATAM Airlines flights from Chicago O'Hare Intl Airport to Santiago

Our best LATAM Airlines deals on Chicago O'Hare Intl Airport to Santiago flight tickets
LATAM Airlines
Mar 4
ORD10:36 amChicago O'Hare Intl
17h 19m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
Mar 31
SCL11:55 pmSantiago Arturo Merino Benitez
19h 15m
1 stop
ORD5:10 pmChicago O'Hare Intl
$562
LATAM Airlines
Mar 30
ORD5:59 pmChicago O'Hare Intl
12h 16m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
Apr 15
SCL7:15 amSantiago Arturo Merino Benitez
17h 44m
2 stops
ORD11:59 pmChicago O'Hare Intl
$573
LATAM Airlines
Mar 4
ORD2:46 pmChicago O'Hare Intl
20h 44m
2 stops
SCL2:30 pmSantiago Arturo Merino Benitez
Mar 31
SCL11:55 pmSantiago Arturo Merino Benitez
19h 15m
1 stop
ORD5:10 pmChicago O'Hare Intl
$575

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 3/30

7:56 am-12:34 am

1 stop14h 38m

Santiago Arturo Merino Benitez

Wed 4/15

4:17 am-1:13 am

1 stop21h 56m

$536

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 3/30

5:59 pm-8:15 am

1 stop12h 16m

Santiago Arturo Merino Benitez

Wed 4/15

7:15 am-11:59 pm

2 stops17h 44m

$573

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 3/30

1:57 pm-8:15 am

2 stops16h 18m

Santiago Arturo Merino Benitez

Wed 4/15

7:45 am-11:59 pm

2 stops17h 14m

$578

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sat 8/1

6:00 am-1:35 pm

2 stops30h 35m

Santiago Arturo Merino Benitez

Sun 8/9

11:05 pm-11:57 pm

2 stops25h 52m

$597

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 6/1

9:44 am-6:00 am

2 stops19h 16m

Santiago Arturo Merino Benitez

Mon 6/8

11:00 pm-2:20 pm

2 stops16h 20m

$602

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 6/1

8:02 am-11:26 pm

1 stop14h 24m

Santiago Arturo Merino Benitez

Sun 6/7

12:01 am-2:06 pm

1 stop15h 05m

$605

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Wed 3/18

7:17 am-10:39 am

2 stops25h 22m

Santiago Arturo Merino Benitez

Wed 3/25

11:24 am-2:16 pm

3 stops28h 52m

$611

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Fri 3/13

6:20 pm-7:50 am

1 stop35h 30m

Santiago Arturo Merino Benitez

Sun 3/22

9:45 pm-11:59 pm

1 stop28h 14m

$614

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Wed 3/18

6:01 pm-5:14 am

3 stops33h 13m

Santiago Arturo Merino Benitez

Wed 3/25

11:24 am-2:16 pm

3 stops28h 52m

$616

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 2/16

6:45 am-7:40 am

1 stop21h 55m

Santiago Arturo Merino Benitez

Sun 2/22

7:15 am-4:50 pm

3 stops36h 35m

$617

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, April is the cheapest month to fly from Chicago O'Hare Intl Airport to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $676. If you don’t want to visit Santiago in April, then you should wait until June to fly from Chicago O'Hare Intl Airport, when ticket prices are also cheap, with an average price of $709.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $821 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Chicago O'Hare Intl Airport for as low as $673 on momondo.

How have Chicago O'Hare Intl Airport to Santiago flight prices changed over time?

As of February 2026, prices for Chicago O'Hare Intl Airport to Santiago flights are approximately 1% cheaper when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Santiago (ORD to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Santiago

Fastest flight time

13h 00m

Direct flights

None
The fastest flight from Chicago O'Hare Intl Airport to Santiago takes 13h 00m
There are no direct flights from Chicago O'Hare Intl Airport to Santiago. There are no popular flight routes from Chicago O'Hare Intl Airport to Santiago.
Search flight deals

  • How far is Chicago O'Hare Intl to Santiago Arturo Merino Benitez by plane?

    Santiago Arturo Merino Benitez is 5321.5 mi away from Chicago O'Hare Intl. 13h 00m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago O'Hare Intl Airport to Santiago?

Best airlines flying from Chicago O'Hare Intl Airport to Santiago

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Santiago with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $468Free CancellationRating
7.5
1,918 reviews
Search LATAM Airlines flights
Air CanadaPriceFrom $484Free CancellationRating
7.1
10,684 reviews
Search Air Canada flights
Copa AirlinesPriceFrom $537Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights
AviancaPriceFrom $564Free CancellationRating
6.5
2,498 reviews
Search Avianca flights
DeltaPriceFrom $583Free CancellationRating
7.9
8,139 reviews
Search Delta flights
American AirlinesPriceFrom $597Free CancellationRating
7.2
11,218 reviews
Search American Airlines flights
United AirlinesPriceFrom $713Free CancellationRating
7.4
9,236 reviews
Search United Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Santiago with flexible booking policies on momondo?

All flight searches from Chicago to Santiago on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Chicago to Santiago?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santiago from Chicago.

I’m not ready to book a flight from Chicago to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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