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Cheap flights from Chicago O'Hare Intl Airport to Santiago from $298

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Santiago departing on 4/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Chicago O'Hare Intl Airport to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
8:02 am - 3:00 am
ORD
-
SCL
17h 58m
1 stop
Copa Airlines Logo
4:41 am - 1:15 am
SCL
-
ORD
21h 34m
1 stop
$550Copa Airlines
Sun, May 3 - Sat, May 9
Copa Airlines Logo
3:21 pm - 7:23 pm
ORD
-
SCL
27h 02m
1 stop
Copa Airlines Logo
11:17 am - 1:15 am
SCL
-
ORD
14h 58m
1 stop
$571Copa Airlines
Fri, May 1 - Sat, May 9
Copa Airlines Logo
3:05 pm - 5:10 am
ORD
-
SCL
13h 05m
1 stop
Copa Airlines Logo
2:22 am - 1:15 am
SCL
-
ORD
23h 53m
1 stop
$598Copa Airlines
Thu, Apr 30 - Tue, May 5
Copa Airlines Logo
3:21 pm - 3:00 am
ORD
-
SCL
34h 39m
1 stop
Copa Airlines Logo
4:09 am - 1:15 am
SCL
-
ORD
22h 06m
1 stop
$622Copa Airlines
Sat, May 16 - Sun, May 24
Multiple Airlines Logo
3:57 pm - 1:30 pm
ORD
-
SCL
44h 33m
2 stops
Multiple Airlines Logo
4:09 am - 2:06 pm
SCL
-
ORD
34h 57m
1 stop
$657Multiple Airlines
Sun, Apr 26 - Sun, May 3
Multiple Airlines Logo
7:50 am - 1:30 pm
ORD
-
SCL
28h 40m
2 stops
Multiple Airlines Logo
4:09 am - 2:06 pm
SCL
-
ORD
34h 57m
1 stop
$658Multiple Airlines
Mon, Apr 27 - Sun, May 3
Multiple Airlines Logo
7:50 am - 11:05 am
ORD
-
SCL
26h 15m
3 stops
Multiple Airlines Logo
6:40 am - 9:20 pm
SCL
-
ORD
15h 40m
1 stop
$659Multiple Airlines
Thu, Apr 16 - Sat, Apr 25
Multiple Airlines Logo
7:50 am - 1:30 pm
ORD
-
SCL
28h 40m
2 stops
Multiple Airlines Logo
6:40 am - 9:20 pm
SCL
-
ORD
15h 40m
1 stop
$661Multiple Airlines
Thu, Apr 30 - Sun, May 10
Multiple Airlines Logo
7:50 am - 3:55 am
ORD
-
SCL
19h 05m
2 stops
Multiple Airlines Logo
6:40 am - 9:20 pm
SCL
-
ORD
15h 40m
1 stop
$664Multiple Airlines
Sun, Apr 26 - Sat, May 9
Multiple Airlines Logo
3:57 pm - 1:30 pm
ORD
-
SCL
44h 33m
2 stops
Multiple Airlines Logo
10:55 pm - 5:41 pm
SCL
-
ORD
19h 46m
1 stop
$665Multiple Airlines
Sun, Apr 26 - Mon, May 4

Copa Airlines flights from Chicago O'Hare Intl Airport to Santiago

Our best Copa Airlines deals on Chicago O'Hare Intl Airport to Santiago flight tickets
Copa Airlines
May 3
ORD8:02 amChicago O'Hare Intl
17h 58m
1 stop
SCL3:00 amSantiago Arturo Merino Benitez
May 9
SCL4:41 amSantiago Arturo Merino Benitez
21h 34m
1 stop
ORD1:15 amChicago O'Hare Intl
$550
Copa Airlines
May 1
ORD3:21 pmChicago O'Hare Intl
27h 02m
1 stop
SCL7:23 pmSantiago Arturo Merino Benitez
May 9
SCL11:17 amSantiago Arturo Merino Benitez
14h 58m
1 stop
ORD1:15 amChicago O'Hare Intl
$571
Copa Airlines
Apr 30
ORD8:06 amChicago O'Hare Intl
13h 37m
1 stop
SCL10:43 pmSantiago Arturo Merino Benitez
May 10
SCL4:09 amSantiago Arturo Merino Benitez
22h 06m
1 stop
ORD1:15 amChicago O'Hare Intl
$598

Avianca flights from Chicago O'Hare Intl Airport to Santiago

Our best Avianca deals on Chicago O'Hare Intl Airport to Santiago flight tickets
Avianca
Apr 13
ORD11:20 pmChicago O'Hare Intl
13h 55m
1 stop
SCL2:15 pmSantiago Arturo Merino Benitez
Apr 20
SCL6:40 amSantiago Arturo Merino Benitez
15h 40m
1 stop
ORD9:20 pmChicago O'Hare Intl
$706
Avianca
May 14
ORD11:20 pmChicago O'Hare Intl
23h 00m
1 stop
SCL11:20 pmSantiago Arturo Merino Benitez
May 21
SCL6:40 amSantiago Arturo Merino Benitez
15h 40m
1 stop
ORD9:20 pmChicago O'Hare Intl
$726
Avianca
May 1
ORD11:20 pmChicago O'Hare Intl
23h 00m
1 stop
SCL11:20 pmSantiago Arturo Merino Benitez
May 9
SCL6:40 amSantiago Arturo Merino Benitez
15h 40m
1 stop
ORD9:20 pmChicago O'Hare Intl
$729

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 3, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 5/3

8:02 am-3:00 am

1 stop17h 58m

Santiago Arturo Merino Benitez

Sat 5/9

4:41 am-1:15 am

1 stop21h 34m

$550

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Fri 5/1

3:21 pm-7:23 pm

1 stop27h 02m

Santiago Arturo Merino Benitez

Sat 5/9

11:17 am-1:15 am

1 stop14h 58m

$571

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Thu 4/30

3:05 pm-5:10 am

1 stop13h 05m

Santiago Arturo Merino Benitez

Tue 5/5

2:22 am-1:15 am

1 stop23h 53m

$598

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sat 5/16

3:21 pm-3:00 am

1 stop34h 39m

Santiago Arturo Merino Benitez

Sun 5/24

4:09 am-1:15 am

1 stop22h 06m

$622

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 4/26

3:57 pm-1:30 pm

2 stops44h 33m

Santiago Arturo Merino Benitez

Sun 5/3

4:09 am-2:06 pm

1 stop34h 57m

$657

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 4/27

7:50 am-1:30 pm

2 stops28h 40m

Santiago Arturo Merino Benitez

Sun 5/3

4:09 am-2:06 pm

1 stop34h 57m

$658

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Thu 4/16

7:50 am-11:05 am

3 stops26h 15m

Santiago Arturo Merino Benitez

Sat 4/25

6:40 am-9:20 pm

1 stop15h 40m

$659

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Thu 4/30

7:50 am-1:30 pm

2 stops28h 40m

Santiago Arturo Merino Benitez

Sun 5/10

6:40 am-9:20 pm

1 stop15h 40m

$661
Quickest round-trip

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 4/26

7:50 am-3:55 am

2 stops19h 05m

Santiago Arturo Merino Benitez

Sat 5/9

6:40 am-9:20 pm

1 stop15h 40m

$664

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 4/26

3:57 pm-1:30 pm

2 stops44h 33m

Santiago Arturo Merino Benitez

Mon 5/4

10:55 pm-5:41 pm

1 stop19h 46m

$665

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago O'Hare Intl Airport and Santiago?

What is the cheapest month to fly to Santiago?

In general, June is the cheapest month to fly from Chicago O'Hare Intl Airport to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $667. If you don’t want to visit Santiago in June, then you should wait until April to fly from Chicago O'Hare Intl Airport, when ticket prices are also cheap, with an average price of $673.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $801 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Chicago O'Hare Intl Airport for as low as $625 on momondo.

How have Chicago O'Hare Intl Airport to Santiago flight prices changed over time?

As of April 2026, prices for Chicago O'Hare Intl Airport to Santiago flights are approximately 42% cheaper when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Santiago (ORD to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Santiago

Fastest flight time

13h 38m

Direct flights

None
The fastest flight from Chicago O'Hare Intl Airport to Santiago takes 13h 38m
There are no direct flights from Chicago O'Hare Intl Airport to Santiago. There are no popular flight routes from Chicago O'Hare Intl Airport to Santiago.
Search flight deals

Frequently asked questions about flying from Chicago O'Hare Intl Airport to Santiago

  • How far is Chicago O'Hare Intl to Santiago Arturo Merino Benitez by plane?

    Santiago Arturo Merino Benitez is 5321.5 mi away from Chicago O'Hare Intl. 13h 38m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago O'Hare Intl Airport to Santiago?

Best airlines flying from Chicago O'Hare Intl Airport to Santiago

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Santiago with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $513Free CancellationRating
7.5
1,578 reviews
Search Copa Airlines flights
AviancaPriceFrom $539Free CancellationRating
6.5
2,505 reviews
Search Avianca flights
LATAM AirlinesPriceFrom $540Free CancellationRating
7.4
1,907 reviews
Search LATAM Airlines flights
DeltaPriceFrom $568Free CancellationRating
7.9
8,373 reviews
Search Delta flights
American AirlinesPriceFrom $597Free CancellationRating
7.1
11,553 reviews
Search American Airlines flights
United AirlinesPriceFrom $626Free CancellationRating
7.4
9,538 reviews
Search United Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Santiago with flexible booking policies on momondo?

All flight searches from Chicago to Santiago on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Chicago to Santiago?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santiago from Chicago.

I’m not ready to book a flight from Chicago to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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