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Cheap flights from Chicago O'Hare Intl Airport to Santiago from $295

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Santiago departing on 11/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago O'Hare Intl Airport to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
12:17 pm - 10:15 pmORD-SCL
30h 58m2 stops
Multiple Airlines Logo
11:25 pm - 9:47 amSCL-ORD
13h 22m1 stop
$571Multiple Airlines
Find Deal
Mon, Nov 10 - Fri, Nov 14
Multiple Airlines Logo
11:08 am - 10:15 pmORD-SCL
33h 07m3 stops
Multiple Airlines Logo
4:25 pm - 4:15 pmSCL-ORD
26h 50m3 stops
$579Multiple Airlines
Find Deal
Wed, Oct 29 - Tue, Nov 4
Multiple Airlines Logo
12:17 pm - 10:15 pmORD-SCL
30h 58m2 stops
Multiple Airlines Logo
11:25 pm - 9:47 amSCL-ORD
13h 22m1 stop
$591Multiple Airlines
Find Deal
Mon, Nov 10 - Thu, Nov 13
Multiple Airlines Logo
12:17 pm - 10:15 pmORD-SCL
30h 58m2 stops
Multiple Airlines Logo
11:25 pm - 6:36 pmSCL-ORD
22h 11m1 stop
$593Multiple Airlines
Find Deal
Fri, Nov 7 - Sun, Dec 7
Multiple Airlines Logo
8:28 am - 10:15 pmORD-SCL
34h 47m3 stops
Multiple Airlines Logo
7:25 am - 8:20 pmSCL-ORD
15h 55m1 stop
$596Multiple Airlines
Find Deal
Tue, Nov 11 - Tue, Nov 18
Avianca Logo
10:20 pm - 3:20 pmORD-SCL
14h 00m1 stop
Avianca Logo
1:35 am - 8:20 pmSCL-ORD
21h 45m1 stop
$610Avianca
Find Deal
Tue, Nov 11 - Mon, Nov 17
Avianca Logo
11:20 pm - 3:20 pmORD-SCL
14h 00m1 stop
Avianca Logo
1:35 am - 8:20 pmSCL-ORD
21h 45m1 stop
$640Avianca
Find Deal
Wed, Oct 29 - Mon, Nov 3
Copa Airlines Logo
7:59 am - 5:58 amORD-SCL
19h 59m1 stop
Copa Airlines Logo
3:23 am - 12:05 amSCL-ORD
23h 42m1 stop
$672Copa Airlines
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Wed, Oct 29 - Mon, Nov 3
LATAM Airlines Logo
10:40 am - 6:55 amORD-SCL
17h 15m1 stop
LATAM Airlines Logo
10:35 am - 11:54 pmSCL-ORD
16h 19m2 stops
$674LATAM Airlines
Find Deal
Mon, Jan 12 - Mon, Jan 26
LATAM Airlines Logo
10:40 am - 6:55 amORD-SCL
17h 15m1 stop
LATAM Airlines Logo
8:15 am - 11:54 pmSCL-ORD
18h 39m2 stops
$684LATAM Airlines
Find Deal
Mon, Feb 2 - Tue, Feb 17

Avianca flights from Chicago O'Hare Intl Airport to Santiago

Our best Avianca deals on Chicago O'Hare Intl Airport to Santiago flight tickets
Avianca
Nov 11
ORD10:20 pmChicago O'Hare Intl
14h 00m
1 stop
SCL3:20 pmSantiago Arturo Merino Benitez
Nov 17
SCL1:35 amSantiago Arturo Merino Benitez
21h 45m
1 stop
ORD8:20 pmChicago O'Hare Intl
$610
Find similar
Avianca
Oct 29
ORD11:20 pmChicago O'Hare Intl
14h 00m
1 stop
SCL3:20 pmSantiago Arturo Merino Benitez
Nov 3
SCL1:35 amSantiago Arturo Merino Benitez
21h 45m
1 stop
ORD8:20 pmChicago O'Hare Intl
$640
Find similar
Avianca
Nov 11
ORD10:20 pmChicago O'Hare Intl
14h 00m
1 stop
SCL3:20 pmSantiago Arturo Merino Benitez
Nov 13
SCL7:25 amSantiago Arturo Merino Benitez
15h 55m
1 stop
ORD8:20 pmChicago O'Hare Intl
$647
Find similar

LATAM Airlines flights from Chicago O'Hare Intl Airport to Santiago

Our best LATAM Airlines deals on Chicago O'Hare Intl Airport to Santiago flight tickets
LATAM Airlines
Jan 12
ORD10:40 amChicago O'Hare Intl
17h 15m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
Jan 26
SCL10:35 amSantiago Arturo Merino Benitez
16h 19m
2 stops
ORD11:54 pmChicago O'Hare Intl
$674
Find similar
LATAM Airlines
Feb 2
ORD10:40 amChicago O'Hare Intl
17h 15m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
Feb 17
SCL8:15 amSantiago Arturo Merino Benitez
18h 39m
2 stops
ORD11:54 pmChicago O'Hare Intl
$684
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 14, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 11/10

12:17 pm-10:15 pm

2 stops30h 58m

Santiago Arturo Merino Benitez

Fri 11/14

11:25 pm-9:47 am

1 stop13h 22m

$571

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Wed 10/29

11:08 am-10:15 pm

3 stops33h 07m

Santiago Arturo Merino Benitez

Tue 11/4

4:25 pm-4:15 pm

3 stops26h 50m

$579

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 11/10

12:17 pm-10:15 pm

2 stops30h 58m

Santiago Arturo Merino Benitez

Thu 11/13

11:25 pm-9:47 am

1 stop13h 22m

$591

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Fri 11/7

12:17 pm-10:15 pm

2 stops30h 58m

Santiago Arturo Merino Benitez

Sun 12/7

11:25 pm-6:36 pm

1 stop22h 11m

$593

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Tue 11/11

8:28 am-10:15 pm

3 stops34h 47m

Santiago Arturo Merino Benitez

Tue 11/18

7:25 am-8:20 pm

1 stop15h 55m

$596

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Tue 11/11

10:20 pm-3:20 pm

1 stop14h 00m

Santiago Arturo Merino Benitez

Mon 11/17

1:35 am-8:20 pm

1 stop21h 45m

$610

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Wed 10/29

11:20 pm-3:20 pm

1 stop14h 00m

Santiago Arturo Merino Benitez

Mon 11/3

1:35 am-8:20 pm

1 stop21h 45m

$640

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Wed 10/29

7:59 am-5:58 am

1 stop19h 59m

Santiago Arturo Merino Benitez

Mon 11/3

3:23 am-12:05 am

1 stop23h 42m

$672

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 1/12

10:40 am-6:55 am

1 stop17h 15m

Santiago Arturo Merino Benitez

Mon 1/26

10:35 am-11:54 pm

2 stops16h 19m

$674

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 2/2

10:40 am-6:55 am

1 stop17h 15m

Santiago Arturo Merino Benitez

Tue 2/17

8:15 am-11:54 pm

2 stops18h 39m

$684

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago O'Hare Intl Airport and Santiago?

What is the cheapest month to fly to Santiago?

In general, April is the cheapest month to fly from Chicago O'Hare Intl Airport to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $690. If you don’t want to visit Santiago in April, then you should wait until May to fly from Chicago O'Hare Intl Airport, when ticket prices are also cheap, with an average price of $758.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $847. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $992.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Chicago O'Hare Intl Airport to Santiago when you can find flight prices for as low as $843. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $942 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $871 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Chicago O'Hare Intl Airport for as low as $673 on momondo.

How have Chicago O'Hare Intl Airport to Santiago flight prices changed over time?

As of October 2025, prices for Chicago O'Hare Intl Airport to Santiago flights are approximately 24% cheaper when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Santiago (ORD to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Santiago

Direct flights

None
There are no direct flights from Chicago O'Hare Intl Airport to Santiago. There are no popular flight routes from Chicago O'Hare Intl Airport to Santiago.
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  • How far is Chicago O'Hare Intl to Santiago Arturo Merino Benitez by plane?

    Santiago Arturo Merino Benitez is 5321.5 mi away from Chicago O'Hare Intl. 12h 55m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago O'Hare Intl Airport to Santiago?

Best airlines flying from Chicago O'Hare Intl Airport to Santiago

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Santiago with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $511Free CancellationRating
7.6
1,547 reviews
Search Copa Airlines flights
AviancaPriceFrom $564Free CancellationRating
6.6
2,451 reviews
Search Avianca flights
LATAM AirlinesPriceFrom $694Free CancellationRating
7.5
1,865 reviews
Search LATAM Airlines flights
DeltaPriceFrom $699Free CancellationRating
7.9
7,972 reviews
Search Delta flights
American AirlinesPriceFrom $703Free CancellationRating
7.2
11,039 reviews
Search American Airlines flights
Air CanadaPriceFrom $707Free CancellationRating
7.1
10,294 reviews
Search Air Canada flights
United AirlinesPriceFrom $748Free CancellationRating
7.4
8,975 reviews
Search United Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Santiago with flexible booking policies on momondo?

All flight searches from Chicago to Santiago on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Chicago to Santiago?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santiago from Chicago.

I’m not ready to book a flight from Chicago to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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