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Cheap flights from Chicago O'Hare Intl Airport to Guayaquil from $160

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Guayaquil departing on 11/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Chicago O'Hare Intl Airport to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
3:20 pm - 12:01 amORD  Chicago O'Hare Intl-GYE Guayaquil Jose Joaquin de Olmedo
8h 41m1 stop Panama City Tocumen Intl
Copa Airlines Logo
2:33 pm - 12:57 amGYE  Guayaquil Jose Joaquin de Olmedo-ORD Chicago O'Hare Intl
10h 24m1 stop Panama City Tocumen Intl
$441Copa Airlines
Sat, Sep 5 - Sat, Oct 3
Copa Airlines Logo
3:20 pm - 12:01 amORD  Chicago O'Hare Intl-GYE Guayaquil Jose Joaquin de Olmedo
8h 41m1 stop Panama City Tocumen Intl
Copa Airlines Logo
4:13 am - 1:59 pmGYE  Guayaquil Jose Joaquin de Olmedo-ORD Chicago O'Hare Intl
9h 46m1 stop Panama City Tocumen Intl
$454Copa Airlines
Sat, Sep 5 - Sat, Sep 12
JetBlue Logo
6:00 am - 3:14 pmORD  Chicago O'Hare Intl-GYE Guayaquil Jose Joaquin de Olmedo
9h 14m1 stop Fort Lauderdale
JetBlue Logo
12:30 pm - 11:10 pmGYE  Guayaquil Jose Joaquin de Olmedo-ORD Chicago O'Hare Intl
10h 40m1 stop Fort Lauderdale
$474JetBlue
Sun, Sep 20 - Mon, Oct 5
American Airlines Logo
6:59 am - 11:22 pmORD  Chicago O'Hare Intl-GYE Guayaquil Jose Joaquin de Olmedo
15h 23m1 stop Miami
American Airlines Logo
7:15 am - 7:56 pmGYE  Guayaquil Jose Joaquin de Olmedo-ORD Chicago O'Hare Intl
13h 41m1 stop Miami
$481American Airlines
Thu, Jan 21 - Mon, Feb 1
American Airlines Logo
6:14 am - 10:39 pmORD  Chicago O'Hare Intl-GYE Guayaquil Jose Joaquin de Olmedo
16h 25m1 stop Miami
American Airlines Logo
2:29 pm - 7:47 amGYE  Guayaquil Jose Joaquin de Olmedo-ORD Chicago O'Hare Intl
17h 18m1 stop Miami
$481American Airlines
Mon, Oct 5 - Sat, Oct 17
Multiple Airlines Logo
6:20 am - 11:37 pmORD  Chicago O'Hare Intl-GYE Guayaquil Jose Joaquin de Olmedo
17h 17m2 stops Atlanta Hartsfield-Jackson Panama City Tocumen Intl
Multiple Airlines Logo
10:05 am - 9:20 pmGYE  Guayaquil Jose Joaquin de Olmedo-ORD Chicago O'Hare Intl
11h 15m1 stop Bogotá El Dorado
$487Multiple Airlines
Tue, Sep 22 - Thu, Oct 22
Multiple Airlines Logo
6:20 am - 11:21 amORD  Chicago O'Hare Intl-GYE Guayaquil Jose Joaquin de Olmedo
29h 01m2 stops Atlanta Hartsfield-Jackson Panama City Tocumen Intl
Multiple Airlines Logo
10:25 am - 8:20 pmGYE  Guayaquil Jose Joaquin de Olmedo-ORD Chicago O'Hare Intl
10h 55m1 stop Bogotá El Dorado
$490Multiple Airlines
Tue, Sep 15 - Sun, Nov 1
Avianca Logo
10:20 pm - 2:25 pmORD  Chicago O'Hare Intl-GYE Guayaquil Jose Joaquin de Olmedo
15h 05m1 stop Bogotá El Dorado
Avianca Logo
10:25 am - 8:20 pmGYE  Guayaquil Jose Joaquin de Olmedo-ORD Chicago O'Hare Intl
10h 55m1 stop Bogotá El Dorado
$548Avianca
Thu, Nov 19 - Wed, Dec 2
Avianca Logo
11:20 pm - 2:35 pmORD  Chicago O'Hare Intl-GYE Guayaquil Jose Joaquin de Olmedo
15h 15m1 stop Bogotá El Dorado
Avianca Logo
3:30 am - 9:20 pmGYE  Guayaquil Jose Joaquin de Olmedo-ORD Chicago O'Hare Intl
17h 50m1 stop Bogotá El Dorado
$548Avianca
Tue, Sep 8 - Mon, Sep 14
United Airlines Logo
7:30 am - 11:37 pmORD  Chicago O'Hare Intl-GYE Guayaquil Jose Joaquin de Olmedo
16h 07m2 stops Houston George Bush Intcntl Panama City Tocumen Intl
United Airlines Logo
12:22 pm - 7:55 amGYE  Guayaquil Jose Joaquin de Olmedo-ORD Chicago O'Hare Intl
19h 33m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
$650United Airlines
Wed, Sep 9 - Wed, Sep 16

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American Airlines flights from Chicago O'Hare Intl Airport to Guayaquil

Our best American Airlines deals on Chicago O'Hare Intl Airport to Guayaquil flight tickets
American Airlines
Oct 5
ORD6:14 amChicago O'Hare Intl
16h 25m
1 stop
GYE10:39 pmGuayaquil Jose Joaquin de Olmedo
Oct 17
GYE2:29 pmGuayaquil Jose Joaquin de Olmedo
17h 18m
1 stop
ORD7:47 amChicago O'Hare Intl
$481
American Airlines
Oct 17
ORD10:08 amChicago O'Hare Intl
12h 31m
2 stops
GYE10:39 pmGuayaquil Jose Joaquin de Olmedo
Oct 24
GYE2:29 pmGuayaquil Jose Joaquin de Olmedo
19h 01m
1 stop
ORD9:30 amChicago O'Hare Intl
$485
American Airlines
Sep 24
ORD7:47 amChicago O'Hare Intl
14h 23m
2 stops
GYE10:10 pmGuayaquil Jose Joaquin de Olmedo
Oct 4
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
18h 33m
1 stop
ORD12:33 amChicago O'Hare Intl
$593

Avianca flights from Chicago O'Hare Intl Airport to Guayaquil

Our best Avianca deals on Chicago O'Hare Intl Airport to Guayaquil flight tickets
Avianca
Nov 1
ORD10:20 pmChicago O'Hare Intl
9h 55m
1 stop
GYE9:15 amGuayaquil Jose Joaquin de Olmedo
Nov 8
GYE9:05 amGuayaquil Jose Joaquin de Olmedo
12h 15m
1 stop
ORD8:20 pmChicago O'Hare Intl
$548
Avianca
Oct 17
ORD11:20 pmChicago O'Hare Intl
9h 35m
1 stop
GYE8:55 amGuayaquil Jose Joaquin de Olmedo
Oct 23
GYE3:30 amGuayaquil Jose Joaquin de Olmedo
17h 50m
1 stop
ORD9:20 pmChicago O'Hare Intl
$560
Avianca
Nov 14
ORD10:20 pmChicago O'Hare Intl
18h 25m
1 stop
GYE5:45 pmGuayaquil Jose Joaquin de Olmedo
Nov 29
GYE6:55 pmGuayaquil Jose Joaquin de Olmedo
26h 25m
1 stop
ORD8:20 pmChicago O'Hare Intl
$566

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 14, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoGuayaquil

ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo

ORDGYE

Chicago O'Hare Intl

Sat 9/5

3:20 pm-12:01 am

1 stop8h 41m

Guayaquil Jose Joaquin de Olmedo

Sat 10/3

2:33 pm-12:57 am

1 stop10h 24m

$441
Quickest round-trip

ChicagoGuayaquil

ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo

ORDGYE

Chicago O'Hare Intl

Sat 9/5

3:20 pm-12:01 am

1 stop8h 41m

Guayaquil Jose Joaquin de Olmedo

Sat 9/12

4:13 am-1:59 pm

1 stop9h 46m

$454

ChicagoGuayaquil

ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo

ORDGYE

Chicago O'Hare Intl

Sun 9/20

6:00 am-3:14 pm

1 stop9h 14m

Guayaquil Jose Joaquin de Olmedo

Mon 10/5

12:30 pm-11:10 pm

1 stop10h 40m

$474

ChicagoGuayaquil

ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo

ORDGYE

Chicago O'Hare Intl

Thu 1/21

6:59 am-11:22 pm

1 stop15h 23m

Guayaquil Jose Joaquin de Olmedo

Mon 2/1

7:15 am-7:56 pm

1 stop13h 41m

$481

ChicagoGuayaquil

ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo

ORDGYE

Chicago O'Hare Intl

Mon 10/5

6:14 am-10:39 pm

1 stop16h 25m

Guayaquil Jose Joaquin de Olmedo

Sat 10/17

2:29 pm-7:47 am

1 stop17h 18m

$481

ChicagoGuayaquil

ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo

ORDGYE

Chicago O'Hare Intl

Tue 9/22

6:20 am-11:37 pm

2 stops17h 17m

Guayaquil Jose Joaquin de Olmedo

Thu 10/22

10:05 am-9:20 pm

1 stop11h 15m

$487

ChicagoGuayaquil

ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo

ORDGYE

Chicago O'Hare Intl

Tue 9/15

6:20 am-11:21 am

2 stops29h 01m

Guayaquil Jose Joaquin de Olmedo

Sun 11/1

10:25 am-8:20 pm

1 stop10h 55m

$490

ChicagoGuayaquil

ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo

ORDGYE

Chicago O'Hare Intl

Thu 11/19

10:20 pm-2:25 pm

1 stop15h 05m

Guayaquil Jose Joaquin de Olmedo

Wed 12/2

10:25 am-8:20 pm

1 stop10h 55m

$548

ChicagoGuayaquil

ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo

ORDGYE

Chicago O'Hare Intl

Tue 9/8

11:20 pm-2:35 pm

1 stop15h 15m

Guayaquil Jose Joaquin de Olmedo

Mon 9/14

3:30 am-9:20 pm

1 stop17h 50m

$548

ChicagoGuayaquil

ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo

ORDGYE

Chicago O'Hare Intl

Wed 9/9

7:30 am-11:37 pm

2 stops16h 07m

Guayaquil Jose Joaquin de Olmedo

Wed 9/16

12:22 pm-7:55 am

2 stops19h 33m

$650

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago O'Hare Intl Airport and Guayaquil?

Prices are currently low for flights on this route.

Typical prices usually range from $467 to $712.
The lowest price recently found on this route was $441.

What is the cheapest month to fly to Guayaquil?

The month of May is another great option to travel to Guayaquil, with average flight prices from Chicago O'Hare Intl Airport averaging around $417.

How far in advance should I book a flight from Chicago O'Hare Intl Airport to Guayaquil?

You are more likely to see cheaper flights to Guayaquil from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Guayaquil for around $506 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Guayaquil from Chicago O'Hare Intl Airport for as low as $484 on momondo.

How have Chicago O'Hare Intl Airport to Guayaquil flight prices changed over time?

As of August 2026, prices for Chicago O'Hare Intl Airport to Guayaquil flights are approximately 14% more expensive when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Guayaquil (ORD to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Guayaquil

Fastest flight time

8h 22m

Direct flights

None
The fastest flight from Chicago O'Hare Intl Airport to Guayaquil takes 8h 22m
There are no direct flights from Chicago O'Hare Intl Airport to Guayaquil. There are no popular flight routes from Chicago O'Hare Intl Airport to Guayaquil.
Search flight deals

Frequently asked questions about flying from Chicago O'Hare Intl Airport to Guayaquil

  • How far is Chicago O'Hare Intl to Guayaquil Jose Joaquin de Olmedo by plane?

    The straight-line distance from Chicago O'Hare Intl to Guayaquil Jose Joaquin de Olmedo is 3090.9 mi. Typically, this will take 8h 22m by plane in normal conditions.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Guayaquil Jose Joaquin de Olmedo Airport were last updated today.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The necessary travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Chicago O'Hare Intl Airport to Guayaquil?

Best airlines flying from Chicago O'Hare Intl Airport to Guayaquil

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $309Free CancellationRating
7.4
10,108 reviews
Search United Airlines flights
AviancaPriceFrom $352Free CancellationRating
6.5
2,536 reviews
Search Avianca flights
JetBluePriceFrom $359Free CancellationRating
7.1
3,036 reviews
Search JetBlue flights
Copa AirlinesPriceFrom $369Free CancellationRating
7.6
1,560 reviews
Search Copa Airlines flights
American AirlinesPriceFrom $387Free CancellationRating
7.1
11,929 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Guayaquil?

Finding the right flight to Guayaquil from Chicago is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Guayaquil quick and easy, saving you time and money.

Can I find flights from Chicago to Guayaquil with flexible booking policies on momondo?

momondo does allow users to show only those flights to Guayaquil from Chicago which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Chicago to Guayaquil?

momondo provides multiple filters to help you find the best flight to Guayaquil from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Guayaquil right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Chicago to Guayaquil flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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