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Cheap flights from North Carolina to Santa Cruz de la Sierra from $256

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from North Carolina to Santa Cruz de la Sierra departing on 1/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from North Carolina to Santa Cruz de la Sierra

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:18 am - 3:44 am
RDU
-
VVI
20h 26m2 stops
United Airlines Logo
11:44 am - 2:06 pm
VVI
-
RDU
27h 22m3 stops
$582United Airlines
Mon, Feb 2 - Mon, Feb 9
United Airlines Logo
6:29 am - 3:38 am
RDU
-
VVI
20h 09m3 stops
United Airlines Logo
11:42 am - 2:04 pm
VVI
-
RDU
26h 22m3 stops
$637United Airlines
Sun, Mar 1 - Tue, Mar 10
United Airlines Logo
10:26 am - 10:50 pm
CLT
-
VVI
36h 24m2 stops
United Airlines Logo
11:42 am - 2:11 pm
VVI
-
CLT
26h 29m2 stops
$662United Airlines
Mon, Mar 9 - Mon, Mar 23
United Airlines Logo
6:33 am - 10:50 pm
CLT
-
VVI
39h 17m2 stops
United Airlines Logo
11:42 am - 2:11 pm
VVI
-
CLT
26h 29m2 stops
$672United Airlines
Sun, Mar 1 - Tue, Mar 10
Multiple Airlines Logo
6:01 pm - 2:35 am
CLT
-
VVI
31h 34m3 stops
Multiple Airlines Logo
3:40 am - 11:56 pm
VVI
-
CLT
20h 16m2 stops
$733Multiple Airlines
Sun, Mar 1 - Mon, Mar 9
Multiple Airlines Logo
6:00 am - 2:35 am
CLT
-
VVI
19h 35m2 stops
Multiple Airlines Logo
3:40 am - 6:48 pm
VVI
-
CLT
16h 08m2 stops
$762Multiple Airlines
Sun, Jan 18 - Sat, Jan 24
United Airlines Logo
6:45 am - 10:50 pm
CLT
-
VVI
39h 05m2 stops
United Airlines Logo
11:44 am - 9:37 pm
VVI
-
CLT
34h 53m2 stops
$772United Airlines
Mon, Feb 2 - Thu, Feb 5
Multiple Airlines Logo
6:01 pm - 2:35 am
CLT
-
VVI
31h 34m3 stops
Multiple Airlines Logo
3:40 am - 10:17 am
VVI
-
CLT
30h 37m3 stops
$777Multiple Airlines
Sun, Mar 1 - Mon, Mar 9
United Airlines Logo
6:23 am - 3:38 am
CLT
-
VVI
21h 15m2 stops
United Airlines Logo
11:42 am - 11:57 pm
VVI
-
CLT
36h 15m2 stops
$787United Airlines
Mon, Mar 16 - Thu, Mar 19
United Airlines Logo
6:23 am - 10:50 pm
CLT
-
VVI
16h 27m2 stops
United Airlines Logo
11:42 am - 9:39 am
VVI
-
CLT
21h 57m2 stops
$797United Airlines
Tue, Mar 10 - Sat, Mar 21

United Airlines flights from North Carolina to Santa Cruz de la Sierra

Our best United Airlines deals on North Carolina to Santa Cruz de la Sierra flight tickets
United Airlines
Feb 2
RDU6:18 amRaleigh-Durham
20h 26m
2 stops
VVI3:44 amSanta Cruz de la Sierra Viru Viru Intl
Feb 9
VVI11:44 amSanta Cruz de la Sierra Viru Viru Intl
27h 22m
3 stops
RDU2:06 pmRaleigh-Durham
$582
Find similar
United Airlines
Mar 1
RDU6:29 amRaleigh-Durham
20h 09m
3 stops
VVI3:38 amSanta Cruz de la Sierra Viru Viru Intl
Mar 10
VVI11:42 amSanta Cruz de la Sierra Viru Viru Intl
26h 22m
3 stops
RDU2:04 pmRaleigh-Durham
$637
Find similar
United Airlines
Mar 9
CLT10:26 amCharlotte Douglas
36h 24m
2 stops
VVI10:50 pmSanta Cruz de la Sierra Viru Viru Intl
Mar 23
VVI11:42 amSanta Cruz de la Sierra Viru Viru Intl
26h 29m
2 stops
CLT2:11 pmCharlotte Douglas
$662
Find similar

LATAM Airlines flights from North Carolina to Santa Cruz de la Sierra

Our best LATAM Airlines deals on North Carolina to Santa Cruz de la Sierra flight tickets
LATAM Airlines
Jan 14
CLT9:29 amCharlotte Douglas
42h 06m
2 stops
VVI4:35 amSanta Cruz de la Sierra Viru Viru Intl
Jan 21
VVI7:26 amSanta Cruz de la Sierra Viru Viru Intl
31h 13m
2 stops
CLT1:39 pmCharlotte Douglas
$945
Find similar
LATAM Airlines
Mar 11
CLT12:43 pmCharlotte Douglas
15h 52m
2 stops
VVI4:35 amSanta Cruz de la Sierra Viru Viru Intl
Mar 22
VVI10:43 amSanta Cruz de la Sierra Viru Viru Intl
24h 01m
2 stops
CLT10:44 amCharlotte Douglas
$3,075
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from North Carolina to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 21, 2025.
Use the filters below to find and compare flights from North Carolina to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RaleighSanta Cruz de la Sierra

RDU - VVI

RDUVVI

Raleigh-Durham

Mon 2/2

6:18 am-3:44 am

2 stops20h 26m

Santa Cruz de la Sierra Viru Viru Intl

Mon 2/9

11:44 am-2:06 pm

3 stops27h 22m

$582

RaleighSanta Cruz de la Sierra

RDU - VVI

RDUVVI

Raleigh-Durham

Sun 3/1

6:29 am-3:38 am

3 stops20h 09m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/10

11:42 am-2:04 pm

3 stops26h 22m

$637

CharlotteSanta Cruz de la Sierra

CLT - VVI

CLTVVI

Charlotte Douglas

Mon 3/9

10:26 am-10:50 pm

2 stops36h 24m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/23

11:42 am-2:11 pm

2 stops26h 29m

$662

CharlotteSanta Cruz de la Sierra

CLT - VVI

CLTVVI

Charlotte Douglas

Sun 3/1

6:33 am-10:50 pm

2 stops39h 17m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/10

11:42 am-2:11 pm

2 stops26h 29m

$672

CharlotteSanta Cruz de la Sierra

CLT - VVI

CLTVVI

Charlotte Douglas

Sun 3/1

6:01 pm-2:35 am

3 stops31h 34m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/9

3:40 am-11:56 pm

2 stops20h 16m

$733

CharlotteSanta Cruz de la Sierra

CLT - VVI

CLTVVI

Charlotte Douglas

Sun 1/18

6:00 am-2:35 am

2 stops19h 35m

Santa Cruz de la Sierra Viru Viru Intl

Sat 1/24

3:40 am-6:48 pm

2 stops16h 08m

$762

CharlotteSanta Cruz de la Sierra

CLT - VVI

CLTVVI

Charlotte Douglas

Mon 2/2

6:45 am-10:50 pm

2 stops39h 05m

Santa Cruz de la Sierra Viru Viru Intl

Thu 2/5

11:44 am-9:37 pm

2 stops34h 53m

$772

CharlotteSanta Cruz de la Sierra

CLT - VVI

CLTVVI

Charlotte Douglas

Sun 3/1

6:01 pm-2:35 am

3 stops31h 34m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/9

3:40 am-10:17 am

3 stops30h 37m

$777

CharlotteSanta Cruz de la Sierra

CLT - VVI

CLTVVI

Charlotte Douglas

Mon 3/16

6:23 am-3:38 am

2 stops21h 15m

Santa Cruz de la Sierra Viru Viru Intl

Thu 3/19

11:42 am-11:57 pm

2 stops36h 15m

$787

CharlotteSanta Cruz de la Sierra

CLT - VVI

CLTVVI

Charlotte Douglas

Tue 3/10

6:23 am-10:50 pm

2 stops16h 27m

Santa Cruz de la Sierra Viru Viru Intl

Sat 3/21

11:42 am-9:39 am

2 stops21h 57m

$797

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Santa Cruz de la Sierra from

How to get the cheapest flight ticket from North Carolina to Santa Cruz de la Sierra

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santa Cruz de la Sierra?

The cheapest day to depart on your flight to Santa Cruz de la Sierra is on a Wednesday when prices can be found for as low as $462. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santa Cruz de la Sierra on Saturday is $773.

What is the cheapest time of day to depart on your flight to Santa Cruz de la Sierra?

In the afternoon is the cheapest time of day to fly from North Carolina to Santa Cruz de la Sierra when you can find flight prices for as low as $517. Flying to Santa Cruz de la Sierra in the afternoon is an ideal time because this is during off-peak travel hours. Flights in the morning are often more expensive with an average ticket price of $691.

Cheap North Carolina to Santa Cruz de la Sierra flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from North Carolina to Santa Cruz de la Sierra

Fastest flight time

16h 49m

Direct flights

None
The fastest flight from North Carolina to Santa Cruz de la Sierra takes 16h 49m
There are no direct flights from North Carolina to Santa Cruz de la Sierra. There are no popular flight routes from North Carolina to Santa Cruz de la Sierra.
Search flight deals

  • When did momondo last update prices for flights from North Carolina to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from North Carolina to Santa Cruz de la Sierra Viru Viru Intl Airport were last updated today.

  • How many operators does momondo search for flights from North Carolina to Santa Cruz de la Sierra Viru Viru Intl Airport?

  • How old do you have to be to fly from North Carolina to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from North Carolina to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The travel and health documents you'll need for your trip to Santa Cruz de la Sierra Viru Viru Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santa Cruz de la Sierra Viru Viru Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from North Carolina to Santa Cruz de la Sierra

Compare and see reviews for airlines that fly from North Carolina to Santa Cruz de la Sierra with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $411Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from North Carolina to Santa Cruz de la Sierra?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from North Carolina to Santa Cruz de la Sierra for you.

Can I find flights from North Carolina to Santa Cruz de la Sierra with flexible booking policies on momondo?

All flight searches from North Carolina to Santa Cruz de la Sierra on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from North Carolina to Santa Cruz de la Sierra?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santa Cruz de la Sierra from North Carolina.

I’m not ready to book a flight from North Carolina to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santa Cruz de la Sierra from North Carolina. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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