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Cheap flights from New Orleans to Santo Domingo from $122

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from New Orleans to Santo Domingo departing on 2/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from New Orleans to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:00 am - 10:58 pm
MSY
-
SDQ
14h 58m2 stops
American Airlines Logo
5:55 am - 4:34 pm
SDQ
-
MSY
11h 39m1 stop
$395American Airlines
Tue, Mar 31 - Tue, Apr 14
American Airlines Logo
6:48 pm - 10:50 am
MSY
-
SDQ
15h 02m1 stop
American Airlines Logo
5:00 pm - 10:04 pm
SDQ
-
MSY
6h 04m1 stop
$396American Airlines
Mon, Jun 1 - Sat, Jul 25
Spirit Airlines Logo
6:40 am - 3:23 pm
MSY
-
SDQ
6h 43m1 stop
Spirit Airlines Logo
3:32 pm - 8:21 am
SDQ
-
MSY
18h 49m1 stop
$401Spirit Airlines
Thu, Jan 1 - Sun, Jan 11
Spirit Airlines Logo
6:40 am - 3:32 am
MSY
-
SDQ
18h 52m2 stops
Spirit Airlines Logo
3:32 pm - 9:29 pm
SDQ
-
MSY
7h 57m1 stop
$410Spirit Airlines
Tue, Jan 6 - Tue, Jan 13
Spirit Airlines Logo
3:10 pm - 2:54 am
MSY
-
SDQ
9h 44m1 stop
Spirit Airlines Logo
3:32 pm - 9:29 pm
SDQ
-
MSY
7h 57m1 stop
$411Spirit Airlines
Sun, Jan 4 - Mon, Jan 12
Spirit Airlines Logo
5:05 am - 2:54 am
MSY
-
SDQ
19h 49m2 stops
Spirit Airlines Logo
3:32 pm - 9:29 pm
SDQ
-
MSY
7h 57m1 stop
$416Spirit Airlines
Tue, Jan 6 - Tue, Jan 13
Spirit Airlines Logo
8:36 pm - 2:20 pm
MSY
-
SDQ
15h 44m2 stops
Spirit Airlines Logo
3:32 pm - 8:55 pm
SDQ
-
MSY
7h 23m1 stop
$419Spirit Airlines
Thu, Feb 12 - Mon, Feb 16
Frontier Logo
6:10 am - 11:56 am
MSY
-
SDQ
51h 46m2 stops
Frontier Logo
11:56 am - 12:31 pm
SDQ
-
MSY
26h 35m2 stops
$427Frontier
Sun, Feb 22 - Sat, Mar 7
United Airlines Logo
12:00 pm - 11:46 pm
MSY
-
SDQ
9h 46m1 stop
United Airlines Logo
2:53 pm - 8:56 am
SDQ
-
MSY
20h 03m2 stops
$438United Airlines
Fri, Jan 30 - Fri, Feb 6
Multiple Airlines Logo
6:15 am - 2:20 pm
MSY
-
SDQ
6h 05m1 stop
Multiple Airlines Logo
12:15 pm - 7:21 am
SDQ
-
MSY
45h 06m2 stops
$441Multiple Airlines
Sun, Feb 22 - Sat, Mar 7

Spirit Airlines flights from New Orleans to Santo Domingo

Our best Spirit Airlines deals on New Orleans to Santo Domingo flight tickets
Spirit Airlines
Dec 25
MSY3:10 pmNew Orleans Louis Armstrong
9h 44m
1 stop
SDQ2:54 amSanto Domingo Las Americas
Jan 17
SDQ3:32 pmSanto Domingo Las Americas
7h 57m
1 stop
MSY9:29 pmNew Orleans Louis Armstrong
$399
Find similar
Spirit Airlines
Jan 1
MSY6:40 amNew Orleans Louis Armstrong
6h 43m
1 stop
SDQ3:23 pmSanto Domingo Las Americas
Jan 11
SDQ3:32 pmSanto Domingo Las Americas
18h 49m
1 stop
MSY8:21 amNew Orleans Louis Armstrong
$401
Find similar
Spirit Airlines
Dec 25
MSY3:10 pmNew Orleans Louis Armstrong
9h 44m
1 stop
SDQ2:54 amSanto Domingo Las Americas
Jan 17
SDQ3:32 pmSanto Domingo Las Americas
7h 57m
1 stop
MSY9:29 pmNew Orleans Louis Armstrong
$408
Find similar

JetBlue flights from New Orleans to Santo Domingo

Our best JetBlue deals on New Orleans to Santo Domingo flight tickets
JetBlue
Dec 22
MSY7:00 amNew Orleans Louis Armstrong
5h 18m
1 stop
SDQ2:18 pmSanto Domingo Las Americas
Jan 17
SDQ3:30 pmSanto Domingo Las Americas
8h 00m
1 stop
MSY9:30 pmNew Orleans Louis Armstrong
$445
Find similar
JetBlue
Mar 20
MSY6:32 pmNew Orleans Louis Armstrong
28h 44m
1 stop
SDQ12:16 amSanto Domingo Las Americas
Mar 26
SDQ2:38 pmSanto Domingo Las Americas
8h 06m
1 stop
MSY9:44 pmNew Orleans Louis Armstrong
$489
Find similar
JetBlue
Dec 23
MSY7:00 amNew Orleans Louis Armstrong
5h 18m
1 stop
SDQ2:18 pmSanto Domingo Las Americas
Jan 17
SDQ3:30 pmSanto Domingo Las Americas
8h 00m
1 stop
MSY9:30 pmNew Orleans Louis Armstrong
$525
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from New Orleans to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 17, 2025.
Use the filters below to find and compare flights from New Orleans to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

New OrleansSanto Domingo

MSY - SDQ

MSYSDQ

New Orleans Louis Armstrong

Tue 3/31

7:00 am-10:58 pm

2 stops14h 58m

Santo Domingo Las Americas

Tue 4/14

5:55 am-4:34 pm

1 stop11h 39m

$395

New OrleansSanto Domingo

MSY - SDQ

MSYSDQ

New Orleans Louis Armstrong

Mon 6/1

6:48 pm-10:50 am

1 stop15h 02m

Santo Domingo Las Americas

Sat 7/25

5:00 pm-10:04 pm

1 stop6h 04m

$396

New OrleansSanto Domingo

MSY - SDQ

MSYSDQ

New Orleans Louis Armstrong

Thu 1/1

6:40 am-3:23 pm

1 stop6h 43m

Santo Domingo Las Americas

Sun 1/11

3:32 pm-8:21 am

1 stop18h 49m

$401

New OrleansSanto Domingo

MSY - SDQ

MSYSDQ

New Orleans Louis Armstrong

Tue 1/6

6:40 am-3:32 am

2 stops18h 52m

Santo Domingo Las Americas

Tue 1/13

3:32 pm-9:29 pm

1 stop7h 57m

$410

New OrleansSanto Domingo

MSY - SDQ

MSYSDQ

New Orleans Louis Armstrong

Sun 1/4

3:10 pm-2:54 am

1 stop9h 44m

Santo Domingo Las Americas

Mon 1/12

3:32 pm-9:29 pm

1 stop7h 57m

$411

New OrleansSanto Domingo

MSY - SDQ

MSYSDQ

New Orleans Louis Armstrong

Tue 1/6

5:05 am-2:54 am

2 stops19h 49m

Santo Domingo Las Americas

Tue 1/13

3:32 pm-9:29 pm

1 stop7h 57m

$416

New OrleansSanto Domingo

MSY - SDQ

MSYSDQ

New Orleans Louis Armstrong

Thu 2/12

8:36 pm-2:20 pm

2 stops15h 44m

Santo Domingo Las Americas

Mon 2/16

3:32 pm-8:55 pm

1 stop7h 23m

$419

New OrleansSanto Domingo

MSY - SDQ

MSYSDQ

New Orleans Louis Armstrong

Sun 2/22

6:10 am-11:56 am

2 stops51h 46m

Santo Domingo Las Americas

Sat 3/7

11:56 am-12:31 pm

2 stops26h 35m

$427

New OrleansSanto Domingo

MSY - SDQ

MSYSDQ

New Orleans Louis Armstrong

Fri 1/30

12:00 pm-11:46 pm

1 stop9h 46m

Santo Domingo Las Americas

Fri 2/6

2:53 pm-8:56 am

2 stops20h 03m

$438

New OrleansSanto Domingo

MSY - SDQ

MSYSDQ

New Orleans Louis Armstrong

Sun 2/22

6:15 am-2:20 pm

1 stop6h 05m

Santo Domingo Las Americas

Sat 3/7

12:15 pm-7:21 am

2 stops45h 06m

$441

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from New Orleans to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in October, then you should wait until January to fly from New Orleans, when ticket prices are also cheap, with an average price of $393.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Wednesday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $502. The most expensive day to fly to Santo Domingo is Monday, with ticket prices averaging around $661.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the afternoon when flights can be purchased for as low as $351. Try not to purchase tickets in the morning because they tend to be around $630. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from New Orleans when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $522 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from New Orleans for as low as $363 on momondo.

How have New Orleans to Santo Domingo flight prices changed over time?

As of December 2025, prices for New Orleans to Santo Domingo flights are approximately 32% more expensive when compared to flights at the same time last year.

When to book flights from New Orleans to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from New Orleans to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap New Orleans to Santo Domingo (MSY to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from New Orleans to Santo Domingo

Fastest flight time

5h 14m

Direct flights

None
The fastest flight from New Orleans to Santo Domingo takes 5h 14m
There are no direct flights from New Orleans to Santo Domingo. There are no popular flight routes from New Orleans to Santo Domingo.
Search flight deals

  • How far is New Orleans Louis Armstrong to Santo Domingo Las Americas by plane?

    There are 1491.2 mi between New Orleans Louis Armstrong and Santo Domingo Las Americas. A reasonable flight in good conditions will take 5h 14m.

  • When did momondo last update prices for flights from New Orleans Louis Armstrong Airport to Santo Domingo Las Americas Airport?

    Prices for flights from New Orleans Louis Armstrong Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from New Orleans Louis Armstrong Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from New Orleans Louis Armstrong Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from New Orleans Louis Armstrong Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from New Orleans to Santo Domingo?

Best airlines flying from New Orleans to Santo Domingo

Compare and see reviews for airlines that fly from New Orleans to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $270Free CancellationRating
6.3
8,189 reviews
Search Spirit Airlines flights
JetBluePriceFrom $357Free CancellationRating
7.2
2,895 reviews
Search JetBlue flights
American AirlinesPriceFrom $384Free CancellationRating
7.2
11,053 reviews
Search American Airlines flights
DeltaPriceFrom $420Free CancellationRating
7.9
8,006 reviews
Search Delta flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from New Orleans to Santo Domingo?

Finding the right flight to Santo Domingo from New Orleans is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santo Domingo quick and easy, saving you time and money.

Can I find flights from New Orleans to Santo Domingo with flexible booking policies on momondo?

Flights from New Orleans to Santo Domingo with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from New Orleans to Santo Domingo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santo Domingo from New Orleans.

I’m not ready to book a flight from New Orleans to Santo Domingo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santo Domingo from New Orleans. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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