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Cheap flights from Myrtle Beach to Panama City from $212

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Panama City departing on 4/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:22 pm - 2:20 pm
MYR
-
PTY
20h 58m
2 stops
American Airlines Logo
1:40 pm - 8:32 am
PTY
-
MYR
17h 52m
2 stops
$461American Airlines
Thu, Mar 19 - Thu, Mar 26
American Airlines Logo
5:19 pm - 12:40 pm
MYR
-
PTY
20h 21m
2 stops
American Airlines Logo
1:40 pm - 8:32 am
PTY
-
MYR
17h 52m
2 stops
$481American Airlines
Thu, Mar 19 - Thu, Mar 26
Multiple Airlines Logo
8:15 pm - 1:00 am
MYR
-
PTY
28h 45m
2 stops
Multiple Airlines Logo
12:03 pm - 8:13 am
PTY
-
MYR
20h 10m
1 stop
$558Multiple Airlines
Wed, Feb 11 - Tue, Feb 17
Multiple Airlines Logo
8:15 pm - 1:00 am
MYR
-
PTY
28h 45m
2 stops
Multiple Airlines Logo
12:03 pm - 8:13 am
PTY
-
MYR
20h 10m
1 stop
$559Multiple Airlines
Wed, Feb 11 - Mon, Feb 16
Delta Logo
2:21 pm - 1:50 pm
MYR
-
PTY
23h 29m
1 stop
Delta Logo
3:15 pm - 11:57 pm
PTY
-
MYR
8h 42m
1 stop
$565Delta
Fri, Feb 13 - Wed, Feb 18
Delta Logo
6:55 pm - 1:50 pm
MYR
-
PTY
18h 55m
1 stop
Delta Logo
3:15 pm - 9:45 am
PTY
-
MYR
18h 30m
1 stop
$572Delta
Fri, Feb 13 - Tue, Feb 17
Multiple Airlines Logo
8:15 pm - 1:00 am
MYR
-
PTY
28h 45m
2 stops
Multiple Airlines Logo
12:03 pm - 8:13 am
PTY
-
MYR
20h 10m
1 stop
$575Multiple Airlines
Wed, Feb 11 - Wed, Feb 18
American Airlines Logo
7:19 pm - 1:27 pm
MYR
-
PTY
18h 08m
2 stops
American Airlines Logo
2:40 pm - 10:44 am
PTY
-
MYR
20h 04m
2 stops
$591American Airlines
Tue, Feb 10 - Tue, Mar 3
Multiple Airlines Logo
9:09 am - 12:40 am
MYR
-
PTY
15h 31m
2 stops
Multiple Airlines Logo
12:03 pm - 8:13 am
PTY
-
MYR
20h 10m
1 stop
$595Multiple Airlines
Fri, Feb 13 - Tue, Feb 17
Multiple Airlines Logo
9:09 am - 12:40 am
MYR
-
PTY
15h 31m
2 stops
Multiple Airlines Logo
12:03 pm - 8:13 am
PTY
-
MYR
20h 10m
1 stop
$596Multiple Airlines
Fri, Feb 13 - Mon, Feb 16

American Airlines flights from Myrtle Beach to Panama City

Our best American Airlines deals on Myrtle Beach to Panama City flight tickets
American Airlines
Mar 19
MYR6:22 pmMyrtle Beach Intl
20h 58m
2 stops
PTY2:20 pmPanama City Tocumen Intl
Mar 26
PTY1:40 pmPanama City Tocumen Intl
17h 52m
2 stops
MYR8:32 amMyrtle Beach Intl
$461
American Airlines
Mar 19
MYR5:19 pmMyrtle Beach Intl
20h 21m
2 stops
PTY12:40 pmPanama City Tocumen Intl
Mar 26
PTY1:40 pmPanama City Tocumen Intl
17h 52m
2 stops
MYR8:32 amMyrtle Beach Intl
$481
American Airlines
Feb 10
MYR7:19 pmMyrtle Beach Intl
18h 08m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Mar 3
PTY2:40 pmPanama City Tocumen Intl
20h 04m
2 stops
MYR10:44 amMyrtle Beach Intl
$591

Delta flights from Myrtle Beach to Panama City

Our best Delta deals on Myrtle Beach to Panama City flight tickets
Delta
Feb 13
MYR2:21 pmMyrtle Beach Intl
23h 29m
1 stop
PTY1:50 pmPanama City Tocumen Intl
Feb 18
PTY3:15 pmPanama City Tocumen Intl
8h 42m
1 stop
MYR11:57 pmMyrtle Beach Intl
$565
Delta
Feb 13
MYR6:55 pmMyrtle Beach Intl
18h 55m
1 stop
PTY1:50 pmPanama City Tocumen Intl
Feb 17
PTY3:15 pmPanama City Tocumen Intl
18h 30m
1 stop
MYR9:45 amMyrtle Beach Intl
$572
Delta
Feb 12
MYR2:21 pmMyrtle Beach Intl
23h 29m
1 stop
PTY1:50 pmPanama City Tocumen Intl
Feb 18
PTY3:15 pmPanama City Tocumen Intl
8h 42m
1 stop
MYR11:57 pmMyrtle Beach Intl
$663

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 3/19

6:22 pm-2:20 pm

2 stops20h 58m

Panama City Tocumen Intl

Thu 3/26

1:40 pm-8:32 am

2 stops17h 52m

$461

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 3/19

5:19 pm-12:40 pm

2 stops20h 21m

Panama City Tocumen Intl

Thu 3/26

1:40 pm-8:32 am

2 stops17h 52m

$481

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Wed 2/11

8:15 pm-1:00 am

2 stops28h 45m

Panama City Tocumen Intl

Tue 2/17

12:03 pm-8:13 am

1 stop20h 10m

$558

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Wed 2/11

8:15 pm-1:00 am

2 stops28h 45m

Panama City Tocumen Intl

Mon 2/16

12:03 pm-8:13 am

1 stop20h 10m

$559

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 2/13

2:21 pm-1:50 pm

1 stop23h 29m

Panama City Tocumen Intl

Wed 2/18

3:15 pm-11:57 pm

1 stop8h 42m

$565

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 2/13

6:55 pm-1:50 pm

1 stop18h 55m

Panama City Tocumen Intl

Tue 2/17

3:15 pm-9:45 am

1 stop18h 30m

$572

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Wed 2/11

8:15 pm-1:00 am

2 stops28h 45m

Panama City Tocumen Intl

Wed 2/18

12:03 pm-8:13 am

1 stop20h 10m

$575

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Tue 2/10

7:19 pm-1:27 pm

2 stops18h 08m

Panama City Tocumen Intl

Tue 3/3

2:40 pm-10:44 am

2 stops20h 04m

$591

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 2/13

9:09 am-12:40 am

2 stops15h 31m

Panama City Tocumen Intl

Tue 2/17

12:03 pm-8:13 am

1 stop20h 10m

$595

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 2/13

9:09 am-12:40 am

2 stops15h 31m

Panama City Tocumen Intl

Mon 2/16

12:03 pm-8:13 am

1 stop20h 10m

$596

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Myrtle Beach to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Myrtle Beach Intl to Panama City Tocumen Intl?

American Airlines, United Airlines, and GOL are the most popular carriers operating from Myrtle Beach Intl to Panama City Tocumen Intl

What airlines fly to Panama City?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Panama City from Myrtle Beach according to our data. American Airlines is the first choice among our users, with 63% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 3 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

When to book flights from Myrtle Beach to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Panama City (MYR to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Panama City

Fastest flight time

7h 50m

Direct flights

None
The fastest flight from Myrtle Beach to Panama City takes 7h 50m
There are no direct flights from Myrtle Beach to Panama City. There are no popular flight routes from Myrtle Beach to Panama City.
Search flight deals

  • How far is Myrtle Beach Intl to Panama City Tocumen Intl by plane?

    The distance between Myrtle Beach Intl and Panama City Tocumen Intl is about 1706.2 mi. Typically, this will take 7h 50m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Myrtle Beach Intl Airport to Panama City Tocumen Intl Airport refresh daily.

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Panama City for you.

Can I find flights from Myrtle Beach to Panama City with flexible booking policies on momondo?

All flight searches from Myrtle Beach to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Myrtle Beach to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Myrtle Beach to Panama City.

I’m not ready to book a flight from Myrtle Beach to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Myrtle Beach and alert you when they change.

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