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Cheap flights from Myrtle Beach to Panama City from $480

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Panama City departing on 3/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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American Airlines Logo
6:35 pm - 2:22 pm
MYR
-
PTY
20h 47m2 stops
American Airlines Logo
1:44 pm - 10:01 am
PTY
-
MYR
19h 17m2 stops
$480American Airlines
Thu, Mar 19 - Thu, Mar 26
American Airlines Logo
7:19 pm - 1:27 pm
MYR
-
PTY
18h 08m2 stops
American Airlines Logo
2:27 pm - 11:35 am
PTY
-
MYR
21h 08m2 stops
$505American Airlines
Sun, Jan 25 - Sun, Feb 1
American Airlines Logo
5:44 pm - 3:31 pm
MYR
-
PTY
21h 47m2 stops
American Airlines Logo
2:27 pm - 10:18 am
PTY
-
MYR
19h 51m2 stops
$540American Airlines
Tue, Jan 6 - Mon, Jan 12
American Airlines Logo
6:17 pm - 12:25 pm
MYR
-
PTY
19h 08m2 stops
American Airlines Logo
1:50 pm - 1:56 pm
PTY
-
MYR
23h 06m2 stops
$580American Airlines
Sat, Jun 6 - Thu, Jun 11
American Airlines Logo
2:53 pm - 1:53 pm
MYR
-
PTY
23h 00m2 stops
American Airlines Logo
2:53 pm - 9:20 am
PTY
-
MYR
18h 27m2 stops
$590American Airlines
Wed, Dec 24 - Tue, Dec 30
Multiple Airlines Logo
8:15 pm - 8:19 pm
MYR
-
PTY
24h 04m1 stop
Multiple Airlines Logo
2:55 am - 7:20 pm
PTY
-
MYR
16h 25m2 stops
$693Multiple Airlines
Sun, Jan 25 - Sat, Jan 31
Multiple Airlines Logo
10:00 am - 2:00 pm
MYR
-
PTY
28h 00m3 stops
Multiple Airlines Logo
2:55 pm - 7:20 pm
PTY
-
MYR
28h 25m2 stops
$721Multiple Airlines
Sun, Jan 25 - Sun, Feb 1
Multiple Airlines Logo
9:54 am - 6:55 pm
MYR
-
PTY
33h 01m3 stops
Multiple Airlines Logo
7:50 pm - 9:04 pm
PTY
-
MYR
25h 14m3 stops
$743Multiple Airlines
Tue, Jan 6 - Mon, Jan 12
Multiple Airlines Logo
10:00 am - 2:00 pm
MYR
-
PTY
28h 00m3 stops
Multiple Airlines Logo
2:55 am - 9:03 am
PTY
-
MYR
30h 08m3 stops
$802Multiple Airlines
Sun, Jan 25 - Sat, Jan 31
Multiple Airlines Logo
9:54 am - 2:00 pm
MYR
-
PTY
28h 06m3 stops
Multiple Airlines Logo
3:50 pm - 10:11 pm
PTY
-
MYR
30h 21m3 stops
$815Multiple Airlines
Wed, Dec 31 - Tue, Jan 6

American Airlines flights from Myrtle Beach to Panama City

Our best American Airlines deals on Myrtle Beach to Panama City flight tickets
American Airlines
Mar 19
MYR6:35 pmMyrtle Beach Intl
20h 47m
2 stops
PTY2:22 pmPanama City Tocumen Intl
Mar 26
PTY1:44 pmPanama City Tocumen Intl
19h 17m
2 stops
MYR10:01 amMyrtle Beach Intl
$480
Find similar
American Airlines
Jan 25
MYR7:19 pmMyrtle Beach Intl
18h 08m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Feb 1
PTY2:27 pmPanama City Tocumen Intl
21h 08m
2 stops
MYR11:35 amMyrtle Beach Intl
$505
Find similar
American Airlines
Jan 6
MYR5:44 pmMyrtle Beach Intl
21h 47m
2 stops
PTY3:31 pmPanama City Tocumen Intl
Jan 12
PTY2:27 pmPanama City Tocumen Intl
19h 51m
2 stops
MYR10:18 amMyrtle Beach Intl
$540
Find similar

Delta flights from Myrtle Beach to Panama City

Our best Delta deals on Myrtle Beach to Panama City flight tickets
Delta
Mar 19
MYR6:00 amMyrtle Beach Intl
7h 55m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Mar 26
PTY2:20 pmPanama City Tocumen Intl
8h 39m
1 stop
MYR11:59 pmMyrtle Beach Intl
$868
Find similar
Delta
Dec 24
MYR6:00 amMyrtle Beach Intl
14h 00m
1 stop
PTY8:00 pmPanama City Tocumen Intl
Dec 30
PTY8:00 amPanama City Tocumen Intl
14h 50m
1 stop
MYR10:50 pmMyrtle Beach Intl
$870
Find similar
Delta
Dec 30
MYR6:00 amMyrtle Beach Intl
14h 00m
1 stop
PTY8:00 pmPanama City Tocumen Intl
Jan 2
PTY8:00 amPanama City Tocumen Intl
10h 14m
1 stop
MYR6:14 pmMyrtle Beach Intl
$939
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 3/19

6:35 pm-2:22 pm

2 stops20h 47m

Panama City Tocumen Intl

Thu 3/26

1:44 pm-10:01 am

2 stops19h 17m

$480

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sun 1/25

7:19 pm-1:27 pm

2 stops18h 08m

Panama City Tocumen Intl

Sun 2/1

2:27 pm-11:35 am

2 stops21h 08m

$505

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Tue 1/6

5:44 pm-3:31 pm

2 stops21h 47m

Panama City Tocumen Intl

Mon 1/12

2:27 pm-10:18 am

2 stops19h 51m

$540

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sat 6/6

6:17 pm-12:25 pm

2 stops19h 08m

Panama City Tocumen Intl

Thu 6/11

1:50 pm-1:56 pm

2 stops23h 06m

$580

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Wed 12/24

2:53 pm-1:53 pm

2 stops23h 00m

Panama City Tocumen Intl

Tue 12/30

2:53 pm-9:20 am

2 stops18h 27m

$590

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sun 1/25

8:15 pm-8:19 pm

1 stop24h 04m

Panama City Tocumen Intl

Sat 1/31

2:55 am-7:20 pm

2 stops16h 25m

$693

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sun 1/25

10:00 am-2:00 pm

3 stops28h 00m

Panama City Tocumen Intl

Sun 2/1

2:55 pm-7:20 pm

2 stops28h 25m

$721

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Tue 1/6

9:54 am-6:55 pm

3 stops33h 01m

Panama City Tocumen Intl

Mon 1/12

7:50 pm-9:04 pm

3 stops25h 14m

$743

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sun 1/25

10:00 am-2:00 pm

3 stops28h 00m

Panama City Tocumen Intl

Sat 1/31

2:55 am-9:03 am

3 stops30h 08m

$802

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Wed 12/31

9:54 am-2:00 pm

3 stops28h 06m

Panama City Tocumen Intl

Tue 1/6

3:50 pm-10:11 pm

3 stops30h 21m

$815

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama City from

How to get the cheapest flight ticket from Myrtle Beach to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Wednesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $475. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $587. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

When to book flights from Myrtle Beach to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Panama City (MYR to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Panama City

Fastest flight time

7h 55m

Direct flights

None
The fastest flight from Myrtle Beach to Panama City takes 7h 55m
There are no direct flights from Myrtle Beach to Panama City. There are no popular flight routes from Myrtle Beach to Panama City.
Search flight deals

  • How far is Myrtle Beach Intl to Panama City Tocumen Intl by plane?

    The distance between Myrtle Beach Intl and Panama City Tocumen Intl is about 1706.2 mi. Typically, this will take 7h 55m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Myrtle Beach Intl Airport to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Myrtle Beach to Panama City?

Best airlines flying from Myrtle Beach to Panama City

Compare and see reviews for airlines that fly from Myrtle Beach to Panama City with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $437Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights

Traveling to a place near Panama City?

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