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Cheap flights from Myrtle Beach to Panama City from $271

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Panama City departing on 4/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
10:00 am - 7:31 pm
MYR
-
PTY
10h 31m
1 stop
United Airlines Logo
7:55 am - 9:59 am
PTY
-
MYR
25h 04m
2 stops
$531United Airlines
Thu, May 28 - Thu, Jun 4
United Airlines Logo
10:00 am - 7:31 pm
MYR
-
PTY
10h 31m
1 stop
United Airlines Logo
10:55 pm - 9:18 am
PTY
-
MYR
9h 23m
1 stop
$547United Airlines
Mon, Jun 1 - Fri, Jun 5
United Airlines Logo
10:34 am - 2:14 pm
MYR
-
PTY
28h 40m
2 stops
United Airlines Logo
10:55 pm - 9:18 am
PTY
-
MYR
9h 23m
1 stop
$551United Airlines
Mon, Jun 1 - Fri, Jun 5
United Airlines Logo
3:08 pm - 7:31 pm
MYR
-
PTY
29h 23m
2 stops
United Airlines Logo
7:55 am - 9:59 am
PTY
-
MYR
25h 04m
2 stops
$568United Airlines
Thu, May 28 - Thu, Jun 4
United Airlines Logo
3:08 pm - 4:12 pm
MYR
-
PTY
26h 04m
2 stops
United Airlines Logo
3:30 pm - 9:59 am
PTY
-
MYR
41h 29m
2 stops
$569United Airlines
Mon, Jun 1 - Fri, Jun 5
United Airlines Logo
5:55 pm - 4:04 am
MYR
-
PTY
11h 09m
1 stop
United Airlines Logo
3:30 pm - 10:18 am
PTY
-
MYR
17h 48m
2 stops
$571United Airlines
Tue, Apr 7 - Tue, Apr 14
United Airlines Logo
11:57 am - 7:31 pm
MYR
-
PTY
8h 34m
1 stop
United Airlines Logo
7:55 am - 2:17 pm
PTY
-
MYR
29h 22m
2 stops
$591United Airlines
Tue, Apr 14 - Fri, Apr 17
American Airlines Logo
4:52 pm - 12:46 pm
MYR
-
PTY
20h 54m
2 stops
American Airlines Logo
1:49 pm - 8:23 am
PTY
-
MYR
17h 34m
2 stops
$601American Airlines
Fri, Apr 17 - Tue, Apr 28
Multiple Airlines Logo
5:56 pm - 4:04 am
MYR
-
PTY
11h 08m
1 stop
Multiple Airlines Logo
10:55 pm - 11:14 am
PTY
-
MYR
11h 19m
1 stop
$609Multiple Airlines
Sat, Apr 18 - Mon, Apr 27
United Airlines Logo
5:55 pm - 4:04 am
MYR
-
PTY
11h 09m
1 stop
United Airlines Logo
10:00 am - 10:18 am
PTY
-
MYR
23h 18m
2 stops
$611United Airlines
Tue, Apr 14 - Fri, Apr 17

American Airlines flights from Myrtle Beach to Panama City

Our best American Airlines deals on Myrtle Beach to Panama City flight tickets
American Airlines
Apr 17
MYR4:52 pmMyrtle Beach Intl
20h 54m
2 stops
PTY12:46 pmPanama City Tocumen Intl
Apr 28
PTY1:49 pmPanama City Tocumen Intl
17h 34m
2 stops
MYR8:23 amMyrtle Beach Intl
$601
American Airlines
Mar 19
MYR6:00 amMyrtle Beach Intl
9h 20m
2 stops
PTY2:20 pmPanama City Tocumen Intl
Mar 26
PTY1:40 pmPanama City Tocumen Intl
17h 52m
2 stops
MYR8:32 amMyrtle Beach Intl
$795
American Airlines
Apr 3
MYR5:19 pmMyrtle Beach Intl
22h 42m
2 stops
PTY3:01 pmPanama City Tocumen Intl
Apr 13
PTY1:49 pmPanama City Tocumen Intl
21h 26m
2 stops
MYR12:15 pmMyrtle Beach Intl
$801

Copa Airlines flights from Myrtle Beach to Panama City

Our best Copa Airlines deals on Myrtle Beach to Panama City flight tickets
Copa Airlines
Mar 31
MYR5:55 pmMyrtle Beach Intl
11h 09m
1 stop
PTY4:04 amPanama City Tocumen Intl
Apr 12
PTY3:30 pmPanama City Tocumen Intl
17h 48m
2 stops
MYR10:18 amMyrtle Beach Intl
$790
Copa Airlines
Apr 1
MYR11:57 amMyrtle Beach Intl
17h 07m
1 stop
PTY4:04 amPanama City Tocumen Intl
Apr 10
PTY3:30 pmPanama City Tocumen Intl
17h 48m
2 stops
MYR10:18 amMyrtle Beach Intl
$831

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 15, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 5/28

10:00 am-7:31 pm

1 stop10h 31m

Panama City Tocumen Intl

Thu 6/4

7:55 am-9:59 am

2 stops25h 04m

$531
Quickest round-trip

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 6/1

10:00 am-7:31 pm

1 stop10h 31m

Panama City Tocumen Intl

Fri 6/5

10:55 pm-9:18 am

1 stop9h 23m

$547

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 6/1

10:34 am-2:14 pm

2 stops28h 40m

Panama City Tocumen Intl

Fri 6/5

10:55 pm-9:18 am

1 stop9h 23m

$551

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 5/28

3:08 pm-7:31 pm

2 stops29h 23m

Panama City Tocumen Intl

Thu 6/4

7:55 am-9:59 am

2 stops25h 04m

$568

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 6/1

3:08 pm-4:12 pm

2 stops26h 04m

Panama City Tocumen Intl

Fri 6/5

3:30 pm-9:59 am

2 stops41h 29m

$569

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Tue 4/7

5:55 pm-4:04 am

1 stop11h 09m

Panama City Tocumen Intl

Tue 4/14

3:30 pm-10:18 am

2 stops17h 48m

$571

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Tue 4/14

11:57 am-7:31 pm

1 stop8h 34m

Panama City Tocumen Intl

Fri 4/17

7:55 am-2:17 pm

2 stops29h 22m

$591

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 4/17

4:52 pm-12:46 pm

2 stops20h 54m

Panama City Tocumen Intl

Tue 4/28

1:49 pm-8:23 am

2 stops17h 34m

$601

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sat 4/18

5:56 pm-4:04 am

1 stop11h 08m

Panama City Tocumen Intl

Mon 4/27

10:55 pm-11:14 am

1 stop11h 19m

$609

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Tue 4/14

5:55 pm-4:04 am

1 stop11h 09m

Panama City Tocumen Intl

Fri 4/17

10:00 am-10:18 am

2 stops23h 18m

$611

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Myrtle Beach to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Myrtle Beach Intl to Panama City Tocumen Intl?

American Airlines, GOL, and Delta are the most popular carriers operating from Myrtle Beach Intl to Panama City Tocumen Intl

What airlines fly to Panama City?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Panama City from Myrtle Beach according to our data. American Airlines is the first choice among our users, with 60% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 3 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

When to book flights from Myrtle Beach to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Panama City (MYR to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Panama City

Fastest flight time

8h 03m

Direct flights

None
The fastest flight from Myrtle Beach to Panama City takes 8h 03m
There are no direct flights from Myrtle Beach to Panama City. There are no popular flight routes from Myrtle Beach to Panama City.
Search flight deals

  • How far is Myrtle Beach Intl to Panama City Tocumen Intl by plane?

    The distance between Myrtle Beach Intl and Panama City Tocumen Intl is about 1706.2 mi. Typically, this will take 8h 03m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Myrtle Beach Intl Airport to Panama City Tocumen Intl Airport refresh daily.

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Panama City for you.

Can I find flights from Myrtle Beach to Panama City with flexible booking policies on momondo?

All flight searches from Myrtle Beach to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Myrtle Beach to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Myrtle Beach to Panama City.

I’m not ready to book a flight from Myrtle Beach to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Myrtle Beach and alert you when they change.

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