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Cheap flights from Myrtle Beach to Panama City from $440

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Panama City departing on 3/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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American Airlines Logo
8:41 pm - 12:10 pmMYR-PTY
16h 29m2 stops
American Airlines Logo
1:50 pm - 9:52 amPTY-MYR
19h 02m2 stops
$440American Airlines
Find Deal
Thu, Mar 19 - Thu, Mar 26
American Airlines Logo
8:41 pm - 2:20 pmMYR-PTY
18h 39m2 stops
American Airlines Logo
1:50 pm - 9:52 amPTY-MYR
19h 02m2 stops
$472American Airlines
Find Deal
Thu, Mar 19 - Thu, Mar 26
American Airlines Logo
8:07 pm - 1:43 pmMYR-PTY
17h 36m2 stops
American Airlines Logo
2:50 pm - 10:42 amPTY-MYR
19h 52m2 stops
$480American Airlines
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Fri, Nov 28 - Fri, Dec 5
Delta Logo
6:00 am - 7:59 pmMYR-PTY
13h 59m1 stop
Delta Logo
3:46 pm - 11:43 pmPTY-MYR
7h 57m1 stop
$516Delta
Find Deal
Fri, Nov 28 - Fri, Dec 5
American Airlines Logo
8:41 pm - 2:20 pmMYR-PTY
18h 39m2 stops
American Airlines Logo
1:55 pm - 8:14 amPTY-MYR
17h 19m2 stops
$535American Airlines
Find Deal
Sat, Apr 4 - Wed, Apr 8
American Airlines Logo
8:41 pm - 2:20 pmMYR-PTY
18h 39m2 stops
American Airlines Logo
1:55 pm - 2:21 pmPTY-MYR
23h 26m2 stops
$624American Airlines
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Sun, Apr 5 - Fri, Apr 10
Multiple Airlines Logo
6:15 am - 10:30 amMYR-PTY
28h 15m3 stops
Multiple Airlines Logo
3:50 pm - 5:48 pmPTY-MYR
25h 58m2 stops
$646Multiple Airlines
Find Deal
Fri, Nov 28 - Fri, Dec 5
Multiple Airlines Logo
6:15 am - 10:30 amMYR-PTY
28h 15m3 stops
Multiple Airlines Logo
11:25 am - 5:48 pmPTY-MYR
30h 23m3 stops
$666Multiple Airlines
Find Deal
Fri, Nov 28 - Fri, Dec 5
Delta Logo
6:00 am - 12:55 pmMYR-PTY
7h 55m1 stop
Delta Logo
2:20 pm - 11:35 pmPTY-MYR
8h 15m1 stop
$798Delta
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Thu, Mar 19 - Thu, Mar 26
Delta Logo
6:00 am - 12:55 pmMYR-PTY
7h 55m1 stop
Delta Logo
2:20 pm - 11:35 pmPTY-MYR
8h 15m1 stop
$1,115Delta
Find Deal
Sat, Apr 4 - Wed, Apr 8

American Airlines flights from Myrtle Beach to Panama City

Our best American Airlines deals on Myrtle Beach to Panama City flight tickets
American Airlines
Mar 19
MYR8:41 pmMyrtle Beach Intl
16h 29m
2 stops
PTY12:10 pmPanama City Tocumen Intl
Mar 26
PTY1:50 pmPanama City Tocumen Intl
19h 02m
2 stops
MYR9:52 amMyrtle Beach Intl
$440
Find similar
American Airlines
Mar 19
MYR8:41 pmMyrtle Beach Intl
18h 39m
2 stops
PTY2:20 pmPanama City Tocumen Intl
Mar 26
PTY1:50 pmPanama City Tocumen Intl
19h 02m
2 stops
MYR9:52 amMyrtle Beach Intl
$472
Find similar
American Airlines
Nov 28
MYR8:07 pmMyrtle Beach Intl
17h 36m
2 stops
PTY1:43 pmPanama City Tocumen Intl
Dec 5
PTY2:50 pmPanama City Tocumen Intl
19h 52m
2 stops
MYR10:42 amMyrtle Beach Intl
$480
Find similar

Delta flights from Myrtle Beach to Panama City

Our best Delta deals on Myrtle Beach to Panama City flight tickets
Delta
Nov 28
MYR6:00 amMyrtle Beach Intl
13h 59m
1 stop
PTY7:59 pmPanama City Tocumen Intl
Dec 5
PTY3:46 pmPanama City Tocumen Intl
7h 57m
1 stop
MYR11:43 pmMyrtle Beach Intl
$516
Find similar
Delta
Mar 19
MYR6:00 amMyrtle Beach Intl
7h 55m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Mar 26
PTY2:20 pmPanama City Tocumen Intl
8h 15m
1 stop
MYR11:35 pmMyrtle Beach Intl
$798
Find similar
Delta
Apr 4
MYR6:00 amMyrtle Beach Intl
7h 55m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Apr 8
PTY2:20 pmPanama City Tocumen Intl
8h 15m
1 stop
MYR11:35 pmMyrtle Beach Intl
$1,115
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 14, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 3/19

8:41 pm-12:10 pm

2 stops16h 29m

Panama City Tocumen Intl

Thu 3/26

1:50 pm-9:52 am

2 stops19h 02m

$440

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 3/19

8:41 pm-2:20 pm

2 stops18h 39m

Panama City Tocumen Intl

Thu 3/26

1:50 pm-9:52 am

2 stops19h 02m

$472

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 11/28

8:07 pm-1:43 pm

2 stops17h 36m

Panama City Tocumen Intl

Fri 12/5

2:50 pm-10:42 am

2 stops19h 52m

$480

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 11/28

6:00 am-7:59 pm

1 stop13h 59m

Panama City Tocumen Intl

Fri 12/5

3:46 pm-11:43 pm

1 stop7h 57m

$516

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sat 4/4

8:41 pm-2:20 pm

2 stops18h 39m

Panama City Tocumen Intl

Wed 4/8

1:55 pm-8:14 am

2 stops17h 19m

$535

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sun 4/5

8:41 pm-2:20 pm

2 stops18h 39m

Panama City Tocumen Intl

Fri 4/10

1:55 pm-2:21 pm

2 stops23h 26m

$624

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 11/28

6:15 am-10:30 am

3 stops28h 15m

Panama City Tocumen Intl

Fri 12/5

3:50 pm-5:48 pm

2 stops25h 58m

$646

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 11/28

6:15 am-10:30 am

3 stops28h 15m

Panama City Tocumen Intl

Fri 12/5

11:25 am-5:48 pm

3 stops30h 23m

$666

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 3/19

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Thu 3/26

2:20 pm-11:35 pm

1 stop8h 15m

$798

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sat 4/4

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Wed 4/8

2:20 pm-11:35 pm

1 stop8h 15m

$1,115

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama City from

How to get the cheapest flight ticket from Myrtle Beach to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Wednesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $475. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $587. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

When to book flights from Myrtle Beach to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Panama City (MYR to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Panama City

Direct flights

None
There are no direct flights from Myrtle Beach to Panama City. There are no popular flight routes from Myrtle Beach to Panama City.
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  • How far is Myrtle Beach Intl to Panama City Tocumen Intl by plane?

    The distance between Myrtle Beach Intl and Panama City Tocumen Intl is about 1706.2 mi. Typically, this will take 7h 55m by plane in normal conditions.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Myrtle Beach Intl Airport to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Myrtle Beach to Panama City?

Best airlines flying from Myrtle Beach to Panama City

Compare and see reviews for airlines that fly from Myrtle Beach to Panama City with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $437Free CancellationRating
7.2
11,042 reviews
Search American Airlines flights

Traveling to a place near Panama City?

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San Blas

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We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Myrtle Beach to Panama City for you.

Can I find flights from Myrtle Beach to Panama City with flexible booking policies on momondo?

All flight searches from Myrtle Beach to Panama City on momondo can be filtered to show those which offer flexible booking policies.

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