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Cheap flights from Missouri to Santo Domingo from $163

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Santo Domingo departing on 1/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Missouri to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
4:27 pm - 11:20 amSTL-SDQ
16h 53m1 stop
Multiple Airlines Logo
4:40 pm - 10:37 pmSDQ-STL
31h 57m2 stops
$358Multiple Airlines
Find Deal
dom., ene. 4 - mar., ene. 13
Multiple Airlines Logo
7:31 pm - 3:23 pmMCI-SDQ
17h 52m1 stop
Multiple Airlines Logo
4:21 pm - 3:45 pmSDQ-MCI
25h 24m2 stops
$385Multiple Airlines
Find Deal
mié., dic. 3 - mié., dic. 10
Spirit Airlines Logo
3:47 pm - 3:32 amMCI-SDQ
9h 45m1 stop
Spirit Airlines Logo
4:40 pm - 3:33 pmSDQ-MCI
24h 53m2 stops
$420Spirit Airlines
Find Deal
lun., ene. 5 - mar., ene. 13
Spirit Airlines Logo
3:47 pm - 3:32 amMCI-SDQ
9h 45m1 stop
Spirit Airlines Logo
4:40 pm - 3:33 pmSDQ-MCI
24h 53m2 stops
$423Spirit Airlines
Find Deal
lun., ene. 5 - mar., ene. 13
American Airlines Logo
5:05 am - 3:58 pmMCI-SDQ
8h 53m1 stop
American Airlines Logo
6:23 pm - 12:25 amSDQ-MCI
8h 02m1 stop
$518American Airlines
Find Deal
mié., dic. 3 - mié., dic. 10
Frontier Logo
9:07 am - 9:42 amSTL-SDQ
22h 35m1 stop
Frontier Logo
4:12 pm - 10:37 pmSDQ-STL
32h 25m2 stops
$521Frontier
Find Deal
lun., dic. 22 - lun., ene. 12
American Airlines Logo
5:04 am - 2:05 pmMCI-SDQ
7h 01m1 stop
American Airlines Logo
3:06 pm - 12:25 amSDQ-MCI
11h 19m1 stop
$522American Airlines
Find Deal
lun., nov. 17 - mié., dic. 3
Delta Logo
9:59 am - 11:59 pmMCI-SDQ
12h 00m1 stop
Delta Logo
7:05 am - 7:19 pmSDQ-MCI
14h 14m1 stop
$526Delta
Find Deal
lun., feb. 23 - vie., feb. 27
Delta Logo
5:50 am - 2:21 pmMCI-SDQ
6h 31m1 stop
Delta Logo
7:31 am - 8:02 pmSDQ-MCI
14h 31m2 stops
$530Delta
Find Deal
vie., ene. 16 - lun., ene. 26
Frontier Logo
3:30 pm - 7:15 pmSTL-SDQ
25h 45m2 stops
Frontier Logo
11:00 am - 8:12 amSDQ-STL
23h 12m1 stop
$568Frontier
Find Deal
sáb., dic. 13 - jue., dic. 18

United Airlines flights from Missouri to Santo Domingo

Our best United Airlines deals on Missouri to Santo Domingo flight tickets
United Airlines
Jan 30
STL11:22 amLambert-St Louis
10h 24m
1 stop
SDQ11:46 pmSanto Domingo Las Americas
Feb 2
SDQ4:18 pmSanto Domingo Las Americas
9h 41m
1 stop
STL11:59 pmLambert-St Louis
$528
Find similar
United Airlines
Jan 30
STL9:57 amLambert-St Louis
11h 49m
2 stops
SDQ11:46 pmSanto Domingo Las Americas
Feb 2
SDQ4:18 pmSanto Domingo Las Americas
9h 41m
1 stop
STL11:59 pmLambert-St Louis
$532
Find similar
United Airlines
Dec 13
STL5:27 pmLambert-St Louis
19h 39m
3 stops
SDQ3:06 pmSanto Domingo Las Americas
Dec 17
SDQ4:18 pmSanto Domingo Las Americas
22h 09m
2 stops
STL12:27 pmLambert-St Louis
$817
Find similar

Delta flights from Missouri to Santo Domingo

Our best Delta deals on Missouri to Santo Domingo flight tickets
Delta
Feb 23
MCI9:59 amKansas City
12h 00m
1 stop
SDQ11:59 pmSanto Domingo Las Americas
Feb 27
SDQ7:05 amSanto Domingo Las Americas
14h 14m
1 stop
MCI7:19 pmKansas City
$526
Find similar
Delta
Jan 16
MCI5:50 amKansas City
6h 31m
1 stop
SDQ2:21 pmSanto Domingo Las Americas
Jan 26
SDQ7:31 amSanto Domingo Las Americas
14h 31m
2 stops
MCI8:02 pmKansas City
$530
Find similar
Delta
Nov 10
STL6:00 amLambert-St Louis
6h 42m
1 stop
SDQ2:42 pmSanto Domingo Las Americas
Nov 12
SDQ3:57 pmSanto Domingo Las Americas
8h 01m
1 stop
STL9:58 pmLambert-St Louis
$568
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated noviembre 6, 2025.
Use the filters below to find and compare flights from Missouri to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

dom. 1/4

4:27 pm-11:20 am

1 stop16h 53m

Santo Domingo Las Americas

mar. 1/13

4:40 pm-10:37 pm

2 stops31h 57m

$358

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

mié. 12/3

7:31 pm-3:23 pm

1 stop17h 52m

Santo Domingo Las Americas

mié. 12/10

4:21 pm-3:45 pm

2 stops25h 24m

$385

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

lun. 1/5

3:47 pm-3:32 am

1 stop9h 45m

Santo Domingo Las Americas

mar. 1/13

4:40 pm-3:33 pm

2 stops24h 53m

$420

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

lun. 1/5

3:47 pm-3:32 am

1 stop9h 45m

Santo Domingo Las Americas

mar. 1/13

4:40 pm-3:33 pm

2 stops24h 53m

$423

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

mié. 12/3

5:05 am-3:58 pm

1 stop8h 53m

Santo Domingo Las Americas

mié. 12/10

6:23 pm-12:25 am

1 stop8h 02m

$518

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

lun. 12/22

9:07 am-9:42 am

1 stop22h 35m

Santo Domingo Las Americas

lun. 1/12

4:12 pm-10:37 pm

2 stops32h 25m

$521

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

lun. 11/17

5:04 am-2:05 pm

1 stop7h 01m

Santo Domingo Las Americas

mié. 12/3

3:06 pm-12:25 am

1 stop11h 19m

$522

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

lun. 2/23

9:59 am-11:59 pm

1 stop12h 00m

Santo Domingo Las Americas

vie. 2/27

7:05 am-7:19 pm

1 stop14h 14m

$526

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

vie. 1/16

5:50 am-2:21 pm

1 stop6h 31m

Santo Domingo Las Americas

lun. 1/26

7:31 am-8:02 pm

2 stops14h 31m

$530

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

sáb. 12/13

3:30 pm-7:15 pm

2 stops25h 45m

Santo Domingo Las Americas

jue. 12/18

11:00 am-8:12 am

1 stop23h 12m

$568

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Missouri to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in February, then you should wait until September to fly from Missouri, when ticket prices are also cheap, with an average price of $533.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Wednesday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $486. The most expensive day to fly to Santo Domingo is Friday, with ticket prices averaging around $765.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the afternoon when flights can be purchased for as low as $445. Try not to purchase tickets in the morning because they tend to be around $610. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Missouri to Santo Domingo flights?

You could potentially save up to 6% on your flight if you consider stops on a Missouri to Santo Domingo flight.

Cheap Missouri to Santo Domingo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Santo Domingo

Direct flights

None
There are no direct flights from Missouri to Santo Domingo. There are no popular flight routes from Missouri to Santo Domingo.
Search flight deals

  • When did momondo last update prices for flights from Missouri to Santo Domingo Las Americas Airport?

    Prices for flights from Missouri to Santo Domingo Las Americas Airport refresh daily.

  • How many operators does momondo search for flights from Missouri to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Missouri to Santo Domingo Las Americas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents required for your trip to Santo Domingo Las Americas Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santo Domingo Las Americas Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Santo Domingo

Compare and see reviews for airlines that fly from Missouri to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $262Free CancellationRating
7.9
8,004 reviews
Search Delta flights
FrontierPriceFrom $371Free CancellationRating
5.8
3,116 reviews
Search Frontier flights
American AirlinesPriceFrom $492Free CancellationRating
7.2
11,041 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Santo Domingo?

It is quick and easy to find Missouri to Santo Domingo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santo Domingo that suits you.

Can I find flights from Missouri to Santo Domingo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santo Domingo from Missouri which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Missouri to Santo Domingo?

Once all potential Missouri to Santo Domingo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Missouri to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from Missouri are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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sáb. 12/6
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