Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Missouri to Santo Domingo from $148

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Santo Domingo departing on 9/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Missouri to Santo Domingo

Cheap round-trip flights

Spirit Airlines Logo
12:13 pm - 5:50 pmMCI-SDQ
27h 37m1 stop
Spirit Airlines Logo
6:55 pm - 11:08 amSDQ-MCI
18h 13m1 stop
$349Spirit Airlines
Find Deal
Fri, Nov 7 - Thu, Nov 13
Spirit Airlines Logo
5:15 am - 12:15 pmMCI-SDQ
6h 00m1 stop
Spirit Airlines Logo
5:05 pm - 10:18 amSDQ-MCI
18h 13m1 stop
$355Spirit Airlines
Find Deal
Thu, Sep 4 - Thu, Sep 11
Logo
5:15 am - 2:36 amMCI-SDQ
20h 21m2 stops
Logo
5:05 pm - 10:18 amSDQ-MCI
18h 13m1 stop
$442
Find Deal
Sat, Sep 6 - Sun, Sep 7
Logo
11:44 am - 10:58 amMCI-SDQ
22h 14m2 stops
Logo
5:05 pm - 10:18 amSDQ-MCI
18h 13m1 stop
$445
Find Deal
Mon, Sep 1 - Sun, Sep 7
Frontier Logo
5:40 pm - 5:25 pmSTL-SDQ
22h 45m2 stops
Frontier Logo
11:50 am - 11:47 pmSDQ-STL
12h 57m1 stop
$446Frontier
Find Deal
Mon, Aug 11 - Sun, Aug 17
American Airlines Logo
5:02 pm - 11:35 amSTL-SDQ
16h 33m1 stop
American Airlines Logo
8:50 am - 9:48 pmSDQ-STL
14h 58m1 stop
$515American Airlines
Find Deal
Tue, Jan 6 - Tue, Jan 20
American Airlines Logo
6:45 pm - 11:50 amSTL-SDQ
15h 05m2 stops
American Airlines Logo
6:50 am - 4:07 pmSDQ-STL
11h 17m2 stops
$519American Airlines
Find Deal
Wed, Nov 26 - Wed, Dec 3
Delta Logo
6:00 am - 2:57 pmSTL-SDQ
6h 57m1 stop
Delta Logo
6:40 am - 4:40 pmSDQ-STL
12h 00m1 stop
$540Delta
Find Deal
Wed, Nov 26 - Wed, Dec 3
Delta Logo
6:00 am - 2:57 pmSTL-SDQ
6h 57m1 stop
Delta Logo
6:40 am - 4:40 pmSDQ-STL
12h 00m1 stop
$565Delta
Find Deal
Mon, Nov 10 - Wed, Nov 12
Frontier Logo
5:40 pm - 11:49 amSTL-SDQ
17h 09m2 stops
Frontier Logo
11:50 am - 9:11 amSDQ-STL
22h 21m2 stops
$647Frontier
Find Deal
Mon, Aug 11 - Sun, Aug 17

American Airlines flights from Missouri to Santo Domingo

Our best American Airlines deals on Missouri to Santo Domingo flight tickets
American Airlines
Jan 6
STL5:02 pmLambert-St Louis
16h 33m
1 stop
SDQ11:35 amSanto Domingo Las Americas
Jan 20
SDQ8:50 amSanto Domingo Las Americas
14h 58m
1 stop
STL9:48 pmLambert-St Louis
$515
Find similar
American Airlines
Nov 26
STL6:45 pmLambert-St Louis
15h 05m
2 stops
SDQ11:50 amSanto Domingo Las Americas
Dec 3
SDQ6:50 amSanto Domingo Las Americas
11h 17m
2 stops
STL4:07 pmLambert-St Louis
$519
Find similar
American Airlines
Aug 4
MCI5:08 amKansas City
9h 12m
1 stop
SDQ3:20 pmSanto Domingo Las Americas
Aug 6
SDQ7:20 pmSanto Domingo Las Americas
15h 57m
2 stops
MCI10:17 amKansas City
$527
Find similar

United Airlines flights from Missouri to Santo Domingo

Our best United Airlines deals on Missouri to Santo Domingo flight tickets
United Airlines
Nov 10
STL8:00 amLambert-St Louis
13h 46m
2 stops
SDQ11:46 pmSanto Domingo Las Americas
Nov 12
SDQ6:00 amSanto Domingo Las Americas
11h 49m
2 stops
STL3:49 pmLambert-St Louis
$679
Find similar
United Airlines
Sep 5
STL5:22 pmLambert-St Louis
7h 28m
1 stop
SDQ1:50 amSanto Domingo Las Americas
Sep 8
SDQ3:20 pmSanto Domingo Las Americas
9h 24m
1 stop
STL11:44 pmLambert-St Louis
$695
Find similar
United Airlines
Nov 10
STL11:49 amLambert-St Louis
9h 57m
1 stop
SDQ11:46 pmSanto Domingo Las Americas
Nov 12
SDQ2:53 pmSanto Domingo Las Americas
10h 51m
1 stop
STL11:44 pmLambert-St Louis
$925
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 1, 2025.
Use the filters below to find and compare flights from Missouri to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

Fri 11/7

12:13 pm-5:50 pm

1 stop27h 37m

Santo Domingo Las Americas

Thu 11/13

6:55 pm-11:08 am

1 stop18h 13m

$349

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

Thu 9/4

5:15 am-12:15 pm

1 stop6h 00m

Santo Domingo Las Americas

Thu 9/11

5:05 pm-10:18 am

1 stop18h 13m

$355

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

Sat 9/6

5:15 am-2:36 am

2 stops20h 21m

Santo Domingo Las Americas

Sun 9/7

5:05 pm-10:18 am

1 stop18h 13m

$442

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

Mon 9/1

11:44 am-10:58 am

2 stops22h 14m

Santo Domingo Las Americas

Sun 9/7

5:05 pm-10:18 am

1 stop18h 13m

$445

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Mon 8/11

5:40 pm-5:25 pm

2 stops22h 45m

Santo Domingo Las Americas

Sun 8/17

11:50 am-11:47 pm

1 stop12h 57m

$446

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Tue 1/6

5:02 pm-11:35 am

1 stop16h 33m

Santo Domingo Las Americas

Tue 1/20

8:50 am-9:48 pm

1 stop14h 58m

$515

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Wed 11/26

6:45 pm-11:50 am

2 stops15h 05m

Santo Domingo Las Americas

Wed 12/3

6:50 am-4:07 pm

2 stops11h 17m

$519

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Wed 11/26

6:00 am-2:57 pm

1 stop6h 57m

Santo Domingo Las Americas

Wed 12/3

6:40 am-4:40 pm

1 stop12h 00m

$540

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Mon 11/10

6:00 am-2:57 pm

1 stop6h 57m

Santo Domingo Las Americas

Wed 11/12

6:40 am-4:40 pm

1 stop12h 00m

$565

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Mon 8/11

5:40 pm-11:49 am

2 stops17h 09m

Santo Domingo Las Americas

Sun 8/17

11:50 am-9:11 am

2 stops22h 21m

$647

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Missouri to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in September, then you should wait until March to fly from Missouri, when ticket prices are also cheap, with an average price of $534.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Wednesday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $486. The most expensive day to fly to Santo Domingo is Friday, with ticket prices averaging around $765.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the afternoon when flights can be purchased for as low as $445. Try not to purchase tickets in the morning because they tend to be around $610. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Missouri to Santo Domingo flights?

You could potentially save up to 6% on your flight if you consider stops on a Missouri to Santo Domingo flight.

Cheap Missouri to Santo Domingo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Santo Domingo

Best Price Found

$148

Fastest flight time

6h 00m

Direct flights

None

Airports in Santo Domingo

1 airport
The best one-way flight to Santo Domingo from Missouri in the past 72 hours is $148. The best round-trip flight deal from Missouri to Santo Domingo found on momondo in the last 72 hours is $349.
The fastest flight from Missouri to Santo Domingo takes 6h 00m
There are no direct flights from Missouri to Santo Domingo. Popular non-direct routes for this connection are Kansas City Airport - Santo Domingo Las Americas Airport and Lambert-St Louis Airport - Santo Domingo Las Americas Airport.
There is 1 airport near Santo Domingo: Santo Domingo Las Americas (SDQ)
Search flight deals

  • When did momondo last update prices for flights from Missouri to Santo Domingo Las Americas Airport?

    Prices for flights from Missouri to Santo Domingo Las Americas Airport refresh daily.

  • How many operators does momondo search for flights from Missouri to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Missouri to Santo Domingo Las Americas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents required for your trip to Santo Domingo Las Americas Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santo Domingo Las Americas Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Santo Domingo

Compare and see reviews for airlines that fly from Missouri to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $262Free CancellationRating
8.0
7,983 reviews
Search Delta flights
FrontierPriceFrom $371Free CancellationRating
5.8
3,241 reviews
Search Frontier flights
American AirlinesPriceFrom $453Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Santo Domingo?

It is quick and easy to find Missouri to Santo Domingo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santo Domingo that suits you.

Can I find flights from Missouri to Santo Domingo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santo Domingo from Missouri which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Missouri to Santo Domingo?

Once all potential Missouri to Santo Domingo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Missouri to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from Missouri are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Santo Domingo trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 8/6
Wed 8/13
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the Dominican Republic