Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Missouri to Santo Domingo from $243

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Santo Domingo departing on 10/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Missouri to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:00 am - 6:34 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
12h 34m1 stop Miami
American Airlines Logo
2:15 pm - 11:59 pmSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
10h 44m1 stop Miami
$600American Airlines
Thu, Sep 10 - Thu, Sep 17
American Airlines Logo
5:00 am - 1:11 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
7h 11m1 stop Miami
American Airlines Logo
10:21 am - 12:27 amSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
15h 06m2 stops Miami Chicago O'Hare Intl
$605American Airlines
Thu, Sep 10 - Thu, Sep 17
American Airlines Logo
5:13 pm - 9:21 amSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
15h 08m2 stops Washington, D.C. Reagan-National Miami
American Airlines Logo
10:21 am - 9:17 pmSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
11h 56m2 stops Miami New York LaGuardia
$605American Airlines
Thu, Sep 10 - Thu, Sep 17
American Airlines Logo
5:00 am - 3:17 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
9h 17m1 stop Miami
American Airlines Logo
10:21 am - 10:42 pmSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
13h 21m2 stops Miami Charlotte Douglas
$605American Airlines
Thu, Sep 10 - Thu, Sep 17
Delta Logo
5:44 am - 1:27 pmMCI  Kansas City-SDQ Santo Domingo Las Americas
6h 43m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:57 pm - 11:56 pmSDQ  Santo Domingo Las Americas-MCI Kansas City
9h 59m1 stop Atlanta Hartsfield-Jackson
$620Delta
Mon, Sep 28 - Tue, Oct 6
Delta Logo
6:59 pm - 1:25 pmMCI  Kansas City-SDQ Santo Domingo Las Americas
16h 26m1 stop New York LaGuardia
Delta Logo
6:45 am - 10:25 pmSDQ  Santo Domingo Las Americas-MCI Kansas City
17h 40m1 stop New York John F Kennedy Intl
$620Delta
Mon, Dec 7 - Fri, Dec 18
Delta Logo
11:51 am - 1:35 amMCI  Kansas City-SDQ Santo Domingo Las Americas
11h 44m1 stop New York John F Kennedy Intl
Delta Logo
6:45 am - 10:25 pmSDQ  Santo Domingo Las Americas-MCI Kansas City
17h 40m1 stop New York John F Kennedy Intl
$620Delta
Tue, Dec 8 - Fri, Dec 18
Copa Airlines Logo
9:59 am - 2:25 amMCI  Kansas City-SDQ Santo Domingo Las Americas
15h 26m2 stops Chicago O'Hare Intl Panama City Tocumen Intl
Copa Airlines Logo
2:25 pm - 8:58 amSDQ  Santo Domingo Las Americas-MCI Kansas City
19h 33m2 stops Panama City Tocumen Intl Chicago O'Hare Intl
$643Copa Airlines
Sat, Oct 24 - Mon, Oct 26
United Airlines Logo
6:00 am - 10:46 pmMCI  Kansas City-SDQ Santo Domingo Las Americas
15h 46m1 stop Newark
United Airlines Logo
3:20 pm - 11:44 pmSDQ  Santo Domingo Las Americas-MCI Kansas City
9h 24m1 stop Newark
$665United Airlines
Thu, Sep 10 - Thu, Sep 24
United Airlines Logo
7:32 am - 10:46 pmMCI  Kansas City-SDQ Santo Domingo Las Americas
14h 14m2 stops Chicago O'Hare Intl Newark
United Airlines Logo
1:10 pm - 11:44 pmSDQ  Santo Domingo Las Americas-MCI Kansas City
11h 34m1 stop Newark
$670United Airlines
Thu, Sep 10 - Thu, Sep 24

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Delta flights from Missouri to Santo Domingo

Our best Delta deals on Missouri to Santo Domingo flight tickets
Delta
Sep 28
MCI5:44 amKansas City
6h 43m
1 stop
SDQ1:27 pmSanto Domingo Las Americas
Oct 6
SDQ2:57 pmSanto Domingo Las Americas
9h 59m
1 stop
MCI11:56 pmKansas City
$620
Delta
Dec 7
MCI2:30 pmKansas City
20h 55m
2 stops
SDQ1:25 pmSanto Domingo Las Americas
Dec 18
SDQ3:00 pmSanto Domingo Las Americas
20h 35m
2 stops
MCI9:35 amKansas City
$625
Delta
Dec 7
MCI6:59 pmKansas City
16h 26m
1 stop
SDQ1:25 pmSanto Domingo Las Americas
Dec 19
SDQ1:57 pmSanto Domingo Las Americas
12h 01m
1 stop
MCI11:58 pmKansas City
$640

United Airlines flights from Missouri to Santo Domingo

Our best United Airlines deals on Missouri to Santo Domingo flight tickets
United Airlines
Sep 10
MCI7:32 amKansas City
14h 14m
2 stops
SDQ10:46 pmSanto Domingo Las Americas
Sep 24
SDQ1:10 pmSanto Domingo Las Americas
11h 34m
1 stop
MCI11:44 pmKansas City
$670
United Airlines
Sep 12
MCI6:00 amKansas City
15h 46m
1 stop
SDQ10:46 pmSanto Domingo Las Americas
Sep 19
SDQ3:20 pmSanto Domingo Las Americas
9h 39m
1 stop
MCI11:59 pmKansas City
$693
United Airlines
Sep 29
STL12:20 pmLambert-St Louis
9h 26m
1 stop
SDQ10:46 pmSanto Domingo Las Americas
Oct 6
SDQ6:00 amSanto Domingo Las Americas
16h 09m
1 stop
STL9:09 pmLambert-St Louis
$740

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 16, 2026.
Use the filters below to find and compare flights from Missouri to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisSanto Domingo

STL Lambert-St Louis - SDQ Santo Domingo Las Americas

STLSDQ

Lambert-St Louis

Thu 9/10

5:00 am-6:34 pm

1 stop12h 34m

Santo Domingo Las Americas

Thu 9/17

2:15 pm-11:59 pm

1 stop10h 44m

$600

St. LouisSanto Domingo

STL Lambert-St Louis - SDQ Santo Domingo Las Americas

STLSDQ

Lambert-St Louis

Thu 9/10

5:00 am-1:11 pm

1 stop7h 11m

Santo Domingo Las Americas

Thu 9/17

10:21 am-12:27 am

2 stops15h 06m

$605

St. LouisSanto Domingo

STL Lambert-St Louis - SDQ Santo Domingo Las Americas

STLSDQ

Lambert-St Louis

Thu 9/10

5:13 pm-9:21 am

2 stops15h 08m

Santo Domingo Las Americas

Thu 9/17

10:21 am-9:17 pm

2 stops11h 56m

$605

St. LouisSanto Domingo

STL Lambert-St Louis - SDQ Santo Domingo Las Americas

STLSDQ

Lambert-St Louis

Thu 9/10

5:00 am-3:17 pm

1 stop9h 17m

Santo Domingo Las Americas

Thu 9/17

10:21 am-10:42 pm

2 stops13h 21m

$605
Quickest round-trip

Kansas CitySanto Domingo

MCI Kansas City - SDQ Santo Domingo Las Americas

MCISDQ

Kansas City

Mon 9/28

5:44 am-1:27 pm

1 stop6h 43m

Santo Domingo Las Americas

Tue 10/6

2:57 pm-11:56 pm

1 stop9h 59m

$620

Kansas CitySanto Domingo

MCI Kansas City - SDQ Santo Domingo Las Americas

MCISDQ

Kansas City

Mon 12/7

6:59 pm-1:25 pm

1 stop16h 26m

Santo Domingo Las Americas

Fri 12/18

6:45 am-10:25 pm

1 stop17h 40m

$620

Kansas CitySanto Domingo

MCI Kansas City - SDQ Santo Domingo Las Americas

MCISDQ

Kansas City

Tue 12/8

11:51 am-1:35 am

1 stop11h 44m

Santo Domingo Las Americas

Fri 12/18

6:45 am-10:25 pm

1 stop17h 40m

$620

Kansas CitySanto Domingo

MCI Kansas City - SDQ Santo Domingo Las Americas

MCISDQ

Kansas City

Sat 10/24

9:59 am-2:25 am

2 stops15h 26m

Santo Domingo Las Americas

Mon 10/26

2:25 pm-8:58 am

2 stops19h 33m

$643

Kansas CitySanto Domingo

MCI Kansas City - SDQ Santo Domingo Las Americas

MCISDQ

Kansas City

Thu 9/10

6:00 am-10:46 pm

1 stop15h 46m

Santo Domingo Las Americas

Thu 9/24

3:20 pm-11:44 pm

1 stop9h 24m

$665

Kansas CitySanto Domingo

MCI Kansas City - SDQ Santo Domingo Las Americas

MCISDQ

Kansas City

Thu 9/10

7:32 am-10:46 pm

2 stops14h 14m

Santo Domingo Las Americas

Thu 9/24

1:10 pm-11:44 pm

1 stop11h 34m

$670

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Missouri to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in September, then you should wait until February to fly from Missouri, when ticket prices are also cheap, with an average price of $592.

Can stopping save me money on Missouri to Santo Domingo flights?

You could potentially save up to 28% on your flight if you consider stops on a Missouri to Santo Domingo flight.

Cheap Missouri to Santo Domingo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Santo Domingo

Fastest flight time

6h 32m

Direct flights

None
The fastest flight from Missouri to Santo Domingo takes 6h 32m
There are no direct flights from Missouri to Santo Domingo. There are no popular flight routes from Missouri to Santo Domingo.
Search flight deals

Frequently asked questions about flying from Missouri to Santo Domingo

  • When did momondo last update prices for flights from Missouri to Santo Domingo Las Americas Airport?

    Prices for flights from Missouri to Santo Domingo Las Americas Airport refresh daily.

  • How many operators does momondo search for flights from Missouri to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Missouri to Santo Domingo Las Americas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents required for your trip to Santo Domingo Las Americas Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santo Domingo Las Americas Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Santo Domingo

Compare and see reviews for airlines that fly from Missouri to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $267Free CancellationRating
7.8
8,502 reviews
Search Delta flights
American AirlinesPriceFrom $521Free CancellationRating
7.1
11,950 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Santo Domingo?

It is quick and easy to find Missouri to Santo Domingo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santo Domingo that suits you.

Can I find flights from Missouri to Santo Domingo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santo Domingo from Missouri which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Missouri to Santo Domingo?

Once all potential Missouri to Santo Domingo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Missouri to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from Missouri are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Santo Domingo trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 9/15
Tue 9/22
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the Dominican Republic