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Cheap flights from Mississippi to Santo Domingo from $204

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to Santo Domingo departing on 5/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Mississippi to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
11:14 am - 1:38 am
MEM
-
SDQ
13h 24m
2 stops
Spirit Airlines Logo
2:52 am - 10:15 am
SDQ
-
MEM
8h 23m
2 stops
$396Spirit Airlines
Tue, Mar 17 - Mon, Mar 23
Multiple Airlines Logo
6:42 pm - 4:29 pm
MEM
-
SDQ
20h 47m
2 stops
Multiple Airlines Logo
2:35 pm - 5:49 pm
SDQ
-
MEM
28h 14m
1 stop
$428Multiple Airlines
Thu, Apr 16 - Thu, Apr 23
Multiple Airlines Logo
4:30 pm - 1:38 am
MEM
-
SDQ
8h 08m
1 stop
Multiple Airlines Logo
2:35 pm - 5:49 pm
SDQ
-
MEM
28h 14m
1 stop
$447Multiple Airlines
Fri, Apr 10 - Sun, Apr 26
Multiple Airlines Logo
6:39 pm - 1:29 pm
MEM
-
SDQ
17h 50m
1 stop
Multiple Airlines Logo
3:44 pm - 7:45 pm
SDQ
-
MEM
29h 01m
2 stops
$462Multiple Airlines
Fri, Apr 17 - Wed, Apr 22
American Airlines Logo
6:39 pm - 1:18 pm
JAN
-
SDQ
17h 39m
2 stops
American Airlines Logo
5:55 pm - 11:03 am
SDQ
-
JAN
18h 08m
2 stops
$533American Airlines
Thu, Apr 16 - Thu, Apr 23
Delta Logo
5:36 am - 1:12 pm
JAN
-
SDQ
6h 36m
1 stop
Delta Logo
2:37 pm - 8:16 pm
SDQ
-
JAN
6h 39m
1 stop
$564Delta
Thu, Apr 16 - Thu, Apr 23
United Airlines Logo
5:00 am - 10:46 pm
BTR
-
SDQ
16h 46m
2 stops
United Airlines Logo
6:00 am - 10:45 pm
SDQ
-
BTR
17h 45m
2 stops
$683United Airlines
Thu, Apr 16 - Thu, Apr 23
United Airlines Logo
5:00 am - 10:46 pm
BTR
-
SDQ
16h 46m
2 stops
United Airlines Logo
6:00 am - 9:10 pm
SDQ
-
BTR
16h 10m
2 stops
$868United Airlines
Tue, Apr 14 - Tue, Apr 21
American Airlines Logo
6:42 pm - 1:10 pm
JAN
-
SDQ
17h 28m
2 stops
American Airlines Logo
5:50 pm - 11:57 am
SDQ
-
JAN
19h 07m
2 stops
$918American Airlines
Thu, Mar 12 - Sun, Mar 15
Delta Logo
5:36 am - 1:12 pm
JAN
-
SDQ
6h 36m
1 stop
Delta Logo
6:05 am - 4:15 pm
SDQ
-
JAN
11h 10m
2 stops
$978Delta
Thu, Apr 16 - Thu, Apr 23

Spirit Airlines flights from Mississippi to Santo Domingo

Our best Spirit Airlines deals on Mississippi to Santo Domingo flight tickets
Spirit Airlines
Mar 17
MEM11:14 amMemphis
13h 24m
2 stops
SDQ1:38 amSanto Domingo Las Americas
Mar 23
SDQ2:52 amSanto Domingo Las Americas
8h 23m
2 stops
MEM10:15 amMemphis
$396
Spirit Airlines
Apr 1
MEM11:14 amMemphis
13h 24m
2 stops
SDQ1:38 amSanto Domingo Las Americas
Apr 7
SDQ2:52 amSanto Domingo Las Americas
8h 23m
2 stops
MEM10:15 amMemphis
$419
Spirit Airlines
Apr 1
MEM11:14 amMemphis
37h 24m
3 stops
SDQ1:38 amSanto Domingo Las Americas
Apr 7
SDQ2:52 amSanto Domingo Las Americas
32h 23m
3 stops
MEM10:15 amMemphis
$540

Delta flights from Mississippi to Santo Domingo

Our best Delta deals on Mississippi to Santo Domingo flight tickets
Delta
Apr 14
MEM6:20 amMemphis
5h 52m
1 stop
SDQ1:12 pmSanto Domingo Las Americas
Apr 21
SDQ2:37 pmSanto Domingo Las Americas
9h 49m
1 stop
MEM11:26 pmMemphis
$519
Delta
Apr 16
JAN5:36 amJackson-Evers Intl
6h 36m
1 stop
SDQ1:12 pmSanto Domingo Las Americas
Apr 23
SDQ2:37 pmSanto Domingo Las Americas
6h 39m
1 stop
JAN8:16 pmJackson-Evers Intl
$564
Delta
Mar 18
MEM6:00 amMemphis
6h 10m
1 stop
SDQ1:10 pmSanto Domingo Las Americas
Mar 24
SDQ6:57 amSanto Domingo Las Americas
11h 00m
2 stops
MEM4:57 pmMemphis
$653

momondo Fare Finder

 
Customize your flight search to find flights from Mississippi to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 3, 2026.
Use the filters below to find and compare flights from Mississippi to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

Tue 3/17

11:14 am-1:38 am

2 stops13h 24m

Santo Domingo Las Americas

Mon 3/23

2:52 am-10:15 am

2 stops8h 23m

$396

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

Thu 4/16

6:42 pm-4:29 pm

2 stops20h 47m

Santo Domingo Las Americas

Thu 4/23

2:35 pm-5:49 pm

1 stop28h 14m

$428

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

Fri 4/10

4:30 pm-1:38 am

1 stop8h 08m

Santo Domingo Las Americas

Sun 4/26

2:35 pm-5:49 pm

1 stop28h 14m

$447

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

Fri 4/17

6:39 pm-1:29 pm

1 stop17h 50m

Santo Domingo Las Americas

Wed 4/22

3:44 pm-7:45 pm

2 stops29h 01m

$462

JacksonSanto Domingo

JAN - SDQ

JANSDQ

Jackson-Evers Intl

Thu 4/16

6:39 pm-1:18 pm

2 stops17h 39m

Santo Domingo Las Americas

Thu 4/23

5:55 pm-11:03 am

2 stops18h 08m

$533

JacksonSanto Domingo

JAN - SDQ

JANSDQ

Jackson-Evers Intl

Thu 4/16

5:36 am-1:12 pm

1 stop6h 36m

Santo Domingo Las Americas

Thu 4/23

2:37 pm-8:16 pm

1 stop6h 39m

$564

Baton RougeSanto Domingo

BTR - SDQ

BTRSDQ

Baton Rouge Ryan

Thu 4/16

5:00 am-10:46 pm

2 stops16h 46m

Santo Domingo Las Americas

Thu 4/23

6:00 am-10:45 pm

2 stops17h 45m

$683

Baton RougeSanto Domingo

BTR - SDQ

BTRSDQ

Baton Rouge Ryan

Tue 4/14

5:00 am-10:46 pm

2 stops16h 46m

Santo Domingo Las Americas

Tue 4/21

6:00 am-9:10 pm

2 stops16h 10m

$868

JacksonSanto Domingo

JAN - SDQ

JANSDQ

Jackson-Evers Intl

Thu 3/12

6:42 pm-1:10 pm

2 stops17h 28m

Santo Domingo Las Americas

Sun 3/15

5:50 pm-11:57 am

2 stops19h 07m

$918

JacksonSanto Domingo

JAN - SDQ

JANSDQ

Jackson-Evers Intl

Thu 4/16

5:36 am-1:12 pm

1 stop6h 36m

Santo Domingo Las Americas

Thu 4/23

6:05 am-4:15 pm

2 stops11h 10m

$978

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Mississippi to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Mississippi to Santo Domingo flights?

You could potentially save up to 19% on your flight if you consider stops on a Mississippi to Santo Domingo flight.

Cheap Mississippi to Santo Domingo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Santo Domingo

Fastest flight time

5h 54m

Direct flights

None
The fastest flight from Mississippi to Santo Domingo takes 5h 54m
There are no direct flights from Mississippi to Santo Domingo. There are no popular flight routes from Mississippi to Santo Domingo.
Search flight deals

  • When did momondo last update prices for flights from Mississippi to Santo Domingo Las Americas Airport?

    Prices for flights from Mississippi to Santo Domingo Las Americas Airport are updated daily.

  • How many operators does momondo search for flights from Mississippi to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Mississippi to Santo Domingo Las Americas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mississippi to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents you'll need for your trip to Santo Domingo Las Americas Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santo Domingo Las Americas Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Santo Domingo?

Finding the right flight to Santo Domingo from Mississippi is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santo Domingo quick and easy, saving you time and money.

Can I find flights from Mississippi to Santo Domingo with flexible booking policies on momondo?

All flight searches from Mississippi to Santo Domingo on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Mississippi to Santo Domingo?

momondo helps you find the best flight between Mississippi and Santo Domingo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Mississippi to Santo Domingo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Mississippi to Santo Domingo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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