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Cheap flights from Mississippi to Santo Domingo from $315

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to Santo Domingo departing on 7/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Mississippi to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:03 pm - 10:50 am
MEM
-
SDQ
14h 47m
1 stop
Multiple Airlines Logo
12:41 pm - 10:55 am
SDQ
-
MEM
23h 14m
2 stops
$500Multiple Airlines
Mon, Jun 15 - Mon, Jun 22
American Airlines Logo
6:18 am - 11:00 pm
JAN
-
SDQ
15h 42m
2 stops
American Airlines Logo
4:24 pm - 11:50 am
SDQ
-
JAN
20h 26m
2 stops
$545American Airlines
Fri, Aug 14 - Tue, Aug 18
Multiple Airlines Logo
11:51 am - 4:29 pm
MEM
-
SDQ
27h 38m
2 stops
Multiple Airlines Logo
2:07 pm - 7:45 am
SDQ
-
MEM
18h 38m
1 stop
$591Multiple Airlines
Tue, Jun 16 - Sat, Jun 20
Delta Logo
6:30 am - 1:23 pm
MEM
-
SDQ
5h 53m
1 stop
Delta Logo
2:41 pm - 8:36 pm
SDQ
-
MEM
6h 55m
1 stop
$600Delta
Wed, Jun 3 - Tue, Jun 30
American Airlines Logo
11:01 am - 10:55 pm
MEM
-
SDQ
10h 54m
2 stops
American Airlines Logo
10:29 am - 9:41 pm
SDQ
-
MEM
12h 12m
2 stops
$605American Airlines
Wed, Jun 3 - Tue, Jun 30
American Airlines Logo
5:36 pm - 9:24 am
MEM
-
SDQ
14h 48m
2 stops
American Airlines Logo
10:25 am - 5:19 pm
SDQ
-
MEM
7h 54m
1 stop
$610American Airlines
Sat, May 30 - Fri, Jun 5
American Airlines Logo
6:32 am - 6:39 pm
MEM
-
SDQ
11h 07m
2 stops
American Airlines Logo
1:35 pm - 10:47 pm
SDQ
-
MEM
10h 12m
1 stop
$615American Airlines
Mon, Sep 7 - Fri, Sep 11
American Airlines Logo
5:40 pm - 12:45 pm
MEM
-
SDQ
18h 05m
1 stop
American Airlines Logo
1:45 pm - 9:41 pm
SDQ
-
MEM
8h 56m
1 stop
$645American Airlines
Wed, Jun 3 - Tue, Jun 30
Delta Logo
5:45 am - 1:12 pm
JAN
-
SDQ
6h 27m
1 stop
Delta Logo
2:37 pm - 11:19 pm
SDQ
-
JAN
9h 42m
1 stop
$740Delta
Fri, Aug 14 - Tue, Aug 18
Delta Logo
5:45 am - 1:12 pm
JAN
-
SDQ
6h 27m
1 stop
Delta Logo
7:29 pm - 11:18 am
SDQ
-
JAN
16h 49m
2 stops
$866Delta
Fri, Aug 14 - Tue, Aug 18

American Airlines flights from Mississippi to Santo Domingo

Our best American Airlines deals on Mississippi to Santo Domingo flight tickets
American Airlines
Aug 14
JAN6:18 amJackson-Evers Intl
15h 42m
2 stops
SDQ11:00 pmSanto Domingo Las Americas
Aug 18
SDQ4:24 pmSanto Domingo Las Americas
20h 26m
2 stops
JAN11:50 amJackson-Evers Intl
$545
American Airlines
Jun 3
MEM11:01 amMemphis
10h 54m
2 stops
SDQ10:55 pmSanto Domingo Las Americas
Jun 30
SDQ10:29 amSanto Domingo Las Americas
12h 12m
2 stops
MEM9:41 pmMemphis
$605
American Airlines
May 30
MEM5:36 pmMemphis
14h 48m
2 stops
SDQ9:24 amSanto Domingo Las Americas
Jun 5
SDQ10:25 amSanto Domingo Las Americas
7h 54m
1 stop
MEM5:19 pmMemphis
$610

Delta flights from Mississippi to Santo Domingo

Our best Delta deals on Mississippi to Santo Domingo flight tickets
Delta
Jun 3
MEM6:30 amMemphis
5h 53m
1 stop
SDQ1:23 pmSanto Domingo Las Americas
Jun 30
SDQ2:41 pmSanto Domingo Las Americas
6h 55m
1 stop
MEM8:36 pmMemphis
$600
Delta
Jun 17
MEM6:20 amMemphis
5h 56m
1 stop
SDQ1:16 pmSanto Domingo Las Americas
Jun 21
SDQ2:41 pmSanto Domingo Las Americas
9h 45m
1 stop
MEM11:26 pmMemphis
$681
Delta
Jun 17
MEM6:20 amMemphis
5h 56m
1 stop
SDQ1:16 pmSanto Domingo Las Americas
Jun 21
SDQ7:35 pmSanto Domingo Las Americas
18h 00m
2 stops
MEM12:35 pmMemphis
$686

momondo Fare Finder

 
Customize your flight search to find flights from Mississippi to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 3, 2026.
Use the filters below to find and compare flights from Mississippi to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

Mon 6/15

7:03 pm-10:50 am

1 stop14h 47m

Santo Domingo Las Americas

Mon 6/22

12:41 pm-10:55 am

2 stops23h 14m

$500

JacksonSanto Domingo

JAN - SDQ

JANSDQ

Jackson-Evers Intl

Fri 8/14

6:18 am-11:00 pm

2 stops15h 42m

Santo Domingo Las Americas

Tue 8/18

4:24 pm-11:50 am

2 stops20h 26m

$545

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

Tue 6/16

11:51 am-4:29 pm

2 stops27h 38m

Santo Domingo Las Americas

Sat 6/20

2:07 pm-7:45 am

1 stop18h 38m

$591
Quickest round-trip

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

Wed 6/3

6:30 am-1:23 pm

1 stop5h 53m

Santo Domingo Las Americas

Tue 6/30

2:41 pm-8:36 pm

1 stop6h 55m

$600

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

Wed 6/3

11:01 am-10:55 pm

2 stops10h 54m

Santo Domingo Las Americas

Tue 6/30

10:29 am-9:41 pm

2 stops12h 12m

$605

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

Sat 5/30

5:36 pm-9:24 am

2 stops14h 48m

Santo Domingo Las Americas

Fri 6/5

10:25 am-5:19 pm

1 stop7h 54m

$610

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

Mon 9/7

6:32 am-6:39 pm

2 stops11h 07m

Santo Domingo Las Americas

Fri 9/11

1:35 pm-10:47 pm

1 stop10h 12m

$615

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

Wed 6/3

5:40 pm-12:45 pm

1 stop18h 05m

Santo Domingo Las Americas

Tue 6/30

1:45 pm-9:41 pm

1 stop8h 56m

$645

JacksonSanto Domingo

JAN - SDQ

JANSDQ

Jackson-Evers Intl

Fri 8/14

5:45 am-1:12 pm

1 stop6h 27m

Santo Domingo Las Americas

Tue 8/18

2:37 pm-11:19 pm

1 stop9h 42m

$740

JacksonSanto Domingo

JAN - SDQ

JANSDQ

Jackson-Evers Intl

Fri 8/14

5:45 am-1:12 pm

1 stop6h 27m

Santo Domingo Las Americas

Tue 8/18

7:29 pm-11:18 am

2 stops16h 49m

$866

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Mississippi to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Mississippi to Santo Domingo flights?

You could potentially save up to 19% on your flight if you consider stops on a Mississippi to Santo Domingo flight.

Cheap Mississippi to Santo Domingo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Santo Domingo

Fastest flight time

5h 41m

Direct flights

None
The fastest flight from Mississippi to Santo Domingo takes 5h 41m
There are no direct flights from Mississippi to Santo Domingo. There are no popular flight routes from Mississippi to Santo Domingo.
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Frequently asked questions about flying from Mississippi to Santo Domingo

  • When did momondo last update prices for flights from Mississippi to Santo Domingo Las Americas Airport?

    Prices for flights from Mississippi to Santo Domingo Las Americas Airport are updated daily.

  • How many operators does momondo search for flights from Mississippi to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Mississippi to Santo Domingo Las Americas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mississippi to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents you'll need for your trip to Santo Domingo Las Americas Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santo Domingo Las Americas Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Santo Domingo?

Finding the right flight to Santo Domingo from Mississippi is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santo Domingo quick and easy, saving you time and money.

Can I find flights from Mississippi to Santo Domingo with flexible booking policies on momondo?

All flight searches from Mississippi to Santo Domingo on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Mississippi to Santo Domingo?

momondo helps you find the best flight between Mississippi and Santo Domingo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Mississippi to Santo Domingo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Mississippi to Santo Domingo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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