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Cheap flights from Mississippi to Santo Domingo from $166

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to Santo Domingo departing on 1/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Mississippi to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:18 pm - 3:35 pmMEM-SDQ
17h 17m1 stop
Multiple Airlines Logo
4:40 pm - 10:19 amSDQ-MEM
19h 39m2 stops
$371Multiple Airlines
Find Deal
dom., ene. 25 - vie., feb. 6
Multiple Airlines Logo
10:40 am - 3:35 pmMEM-SDQ
26h 55m1 stop
Multiple Airlines Logo
4:40 pm - 10:19 amSDQ-MEM
19h 39m2 stops
$376Multiple Airlines
Find Deal
dom., ene. 11 - vie., ene. 16
Multiple Airlines Logo
10:40 am - 3:35 pmMEM-SDQ
26h 55m1 stop
Multiple Airlines Logo
4:40 pm - 9:50 amSDQ-MEM
19h 10m1 stop
$383Multiple Airlines
Find Deal
dom., ene. 11 - sáb., ene. 17
Multiple Airlines Logo
10:40 am - 3:35 pmMEM-SDQ
26h 55m1 stop
Multiple Airlines Logo
3:35 pm - 4:52 pmSDQ-MEM
27h 17m2 stops
$384Multiple Airlines
Find Deal
dom., ene. 11 - sáb., ene. 17
Spirit Airlines Logo
8:17 pm - 3:32 amMEM-SDQ
5h 15m1 stop
Spirit Airlines Logo
8:20 am - 7:22 pmSDQ-MEM
13h 02m1 stop
$399Spirit Airlines
Find Deal
jue., dic. 25 - lun., dic. 29
Spirit Airlines Logo
8:17 pm - 3:32 amMEM-SDQ
5h 15m1 stop
Spirit Airlines Logo
3:59 am - 7:22 pmSDQ-MEM
17h 23m2 stops
$400Spirit Airlines
Find Deal
jue., dic. 25 - dom., dic. 28
Delta Logo
6:59 pm - 5:35 pmBTR-SDQ
21h 36m2 stops
Delta Logo
7:00 pm - 3:10 pmSDQ-BTR
21h 10m2 stops
$510Delta
Find Deal
lun., mar. 9 - mié., mar. 18
Delta Logo
6:00 am - 1:15 pmBTR-SDQ
6h 15m1 stop
Delta Logo
2:40 pm - 10:03 pmSDQ-BTR
8h 23m1 stop
$518Delta
Find Deal
mar., mar. 10 - mar., mar. 17
American Airlines Logo
4:24 pm - 2:06 pmJAN-SDQ
19h 42m2 stops
American Airlines Logo
7:00 am - 4:55 pmSDQ-JAN
11h 55m2 stops
$632American Airlines
Find Deal
dom., feb. 22 - mié., feb. 25
American Airlines Logo
4:22 pm - 10:07 amJAN-SDQ
15h 45m2 stops
American Airlines Logo
6:57 pm - 12:05 pmSDQ-JAN
19h 08m2 stops
$1,362American Airlines
Find Deal
dom., dic. 21 - dom., ene. 4

American Airlines flights from Mississippi to Santo Domingo

Our best American Airlines deals on Mississippi to Santo Domingo flight tickets
American Airlines
Jan 25
MEM6:00 amMemphis
7h 45m
1 stop
SDQ3:45 pmSanto Domingo Las Americas
Feb 6
SDQ1:23 pmSanto Domingo Las Americas
12h 35m
1 stop
MEM11:58 pmMemphis
$468
Find similar
American Airlines
Jan 13
MEM3:58 pmMemphis
18h 23m
2 stops
SDQ12:21 pmSanto Domingo Las Americas
Jan 18
SDQ6:00 amSanto Domingo Las Americas
13h 49m
1 stop
MEM5:49 pmMemphis
$487
Find similar
American Airlines
May 17
MEM7:43 amMemphis
13h 07m
2 stops
SDQ9:50 pmSanto Domingo Las Americas
May 24
SDQ8:00 amSanto Domingo Las Americas
10h 04m
1 stop
MEM5:04 pmMemphis
$512
Find similar

Delta flights from Mississippi to Santo Domingo

Our best Delta deals on Mississippi to Santo Domingo flight tickets
Delta
Jan 25
MEM11:57 amMemphis
10h 33m
2 stops
SDQ12:30 amSanto Domingo Las Americas
Feb 6
SDQ7:31 amSanto Domingo Las Americas
13h 57m
2 stops
MEM7:28 pmMemphis
$472
Find similar
Delta
Mar 9
BTR6:59 pmBaton Rouge Ryan
21h 36m
2 stops
SDQ5:35 pmSanto Domingo Las Americas
Mar 18
SDQ7:00 pmSanto Domingo Las Americas
21h 10m
2 stops
BTR3:10 pmBaton Rouge Ryan
$510
Find similar
Delta
Mar 10
BTR6:00 amBaton Rouge Ryan
6h 15m
1 stop
SDQ1:15 pmSanto Domingo Las Americas
Mar 17
SDQ2:40 pmSanto Domingo Las Americas
8h 23m
1 stop
BTR10:03 pmBaton Rouge Ryan
$518
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Mississippi to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated noviembre 26, 2025.
Use the filters below to find and compare flights from Mississippi to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

dom. 1/25

8:18 pm-3:35 pm

1 stop17h 17m

Santo Domingo Las Americas

vie. 2/6

4:40 pm-10:19 am

2 stops19h 39m

$371

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

dom. 1/11

10:40 am-3:35 pm

1 stop26h 55m

Santo Domingo Las Americas

vie. 1/16

4:40 pm-10:19 am

2 stops19h 39m

$376

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

dom. 1/11

10:40 am-3:35 pm

1 stop26h 55m

Santo Domingo Las Americas

sáb. 1/17

4:40 pm-9:50 am

1 stop19h 10m

$383

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

dom. 1/11

10:40 am-3:35 pm

1 stop26h 55m

Santo Domingo Las Americas

sáb. 1/17

3:35 pm-4:52 pm

2 stops27h 17m

$384

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

jue. 12/25

8:17 pm-3:32 am

1 stop5h 15m

Santo Domingo Las Americas

lun. 12/29

8:20 am-7:22 pm

1 stop13h 02m

$399

MemphisSanto Domingo

MEM - SDQ

MEMSDQ

Memphis

jue. 12/25

8:17 pm-3:32 am

1 stop5h 15m

Santo Domingo Las Americas

dom. 12/28

3:59 am-7:22 pm

2 stops17h 23m

$400

Baton RougeSanto Domingo

BTR - SDQ

BTRSDQ

Baton Rouge Ryan

lun. 3/9

6:59 pm-5:35 pm

2 stops21h 36m

Santo Domingo Las Americas

mié. 3/18

7:00 pm-3:10 pm

2 stops21h 10m

$510

Baton RougeSanto Domingo

BTR - SDQ

BTRSDQ

Baton Rouge Ryan

mar. 3/10

6:00 am-1:15 pm

1 stop6h 15m

Santo Domingo Las Americas

mar. 3/17

2:40 pm-10:03 pm

1 stop8h 23m

$518

JacksonSanto Domingo

JAN - SDQ

JANSDQ

Jackson-Evers Intl

dom. 2/22

4:24 pm-2:06 pm

2 stops19h 42m

Santo Domingo Las Americas

mié. 2/25

7:00 am-4:55 pm

2 stops11h 55m

$632

JacksonSanto Domingo

JAN - SDQ

JANSDQ

Jackson-Evers Intl

dom. 12/21

4:22 pm-10:07 am

2 stops15h 45m

Santo Domingo Las Americas

dom. 1/4

6:57 pm-12:05 pm

2 stops19h 08m

$1,362

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Mississippi to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Saturday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $454. The most expensive day to fly to Santo Domingo is Thursday, with ticket prices averaging around $1,172.

Can stopping save me money on Mississippi to Santo Domingo flights?

You could potentially save up to 2% on your flight if you consider stops on a Mississippi to Santo Domingo flight.

Cheap Mississippi to Santo Domingo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Santo Domingo

Fastest flight time

5h 15m

Direct flights

None
The fastest flight from Mississippi to Santo Domingo takes 5h 15m
There are no direct flights from Mississippi to Santo Domingo. There are no popular flight routes from Mississippi to Santo Domingo.
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  • When did momondo last update prices for flights from Mississippi to Santo Domingo Las Americas Airport?

    Prices for flights from Mississippi to Santo Domingo Las Americas Airport are updated daily.

  • How many operators does momondo search for flights from Mississippi to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Mississippi to Santo Domingo Las Americas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mississippi to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents you'll need for your trip to Santo Domingo Las Americas Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santo Domingo Las Americas Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Santo Domingo?

Finding the right flight to Santo Domingo from Mississippi is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santo Domingo quick and easy, saving you time and money.

Can I find flights from Mississippi to Santo Domingo with flexible booking policies on momondo?

All flight searches from Mississippi to Santo Domingo on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Mississippi to Santo Domingo?

momondo helps you find the best flight between Mississippi and Santo Domingo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Mississippi to Santo Domingo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Mississippi to Santo Domingo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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