Cheap flights from Madrid to Istanbul from $105

In general, February is the cheapest month to fly from Madrid to Istanbul Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $225. If you don’t want to visit Istanbul Airport in February, then you should wait until January to fly from Madrid, when ticket prices are also cheap, with an average price of $266.

Our data shows that Thursday is the least expensive day to fly to Istanbul Airport. Tickets to fly out on this day can be as low as $423. On the other hand, Sunday is the most expensive day to depart from Madrid because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $710.

At noon is the cheapest time of day to fly from Madrid to Istanbul Airport when you can find flight prices for as low as $423. Flying to Istanbul Airport at noon is an ideal time because this is during off-peak travel hours. Flights in the afternoon are often more expensive with an average ticket price of $603.

Fly from Madrid Barajas to Istanbul for the best Madrid Barajas - Istanbul flight prices

You are more likely to see cheaper flights to Istanbul Airport from Madrid when booking weeks ahead of your departure date. In general, you can expect to find flights to Istanbul Airport for around $320 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Istanbul Airport from Madrid for as low as $287 on momondo.

There are 3 cabin classes available to choose from on Madrid to Istanbul Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 47% on your flight if you consider stops on a Madrid to Istanbul Airport flight.

As of September 2026, prices for Madrid to Istanbul Airport flights are approximately 10% cheaper when compared to flights at the same time last year.

Air Serbia, KLM, and TAROM are the most popular carriers operating from Madrid Barajas to Istanbul

Pegasus Airlines, Turkish Airlines and Air Europa are the top three most popular airlines that fly to Istanbul Airport from Madrid according to our data. Pegasus Airlines is the first choice among our users, with 40% of people opting to fly with this airline when traveling to Istanbul Airport. Keep in mind that there are 4 different airlines that fly to Istanbul Airport on a routine basis, so you have a few additional options to choose from.

Historically, on average around 18% of flights between Madrid and Istanbul have experienced a delay on any given week. The average delay length over the past 12 months has been 134 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Wednesday has historically seen more delays on average compared to the rest of the week.

According to our data, Turkish Airlines have had the least number of delays on this route over the last 12 months; with about 13% of their flights experiencing any sort of delay.

Munich (MUC) was the most common stop: 75% of momondo users choosing 1-stop flights on this route connected there.

Flights via Bucharest (OTP) offer the lowest average round-trip price of $208.

Flights connecting via Bucharest (OTP) have the shortest average one-way travel time: 8h 20m.

Munich (MUC) has the shortest average layover time for this route: 4h 08m.

13 flights are operational daily from Madrid to Istanbul Airport as of September 2026. The most popular departure time for this route is 7:00AM, with 39% of flights per day taking off at noon.

As of September 2026, there are 94 flights per week flying from Madrid to Istanbul Airport. The most common day of the week flights depart is Wed, with 22% of flights taking off on this day.