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Cheap flights from Louisville to Santiago de los Caballeros from $181

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Santiago de los Caballeros departing on 3/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Louisville to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:13 pm - 2:23 pm
SDF
-
STI
17h 10m
1 stop
Multiple Airlines Logo
2:46 am - 11:47 am
STI
-
SDF
9h 01m
1 stop
$409Multiple Airlines
Mon, Mar 30 - Mon, Apr 6
Spirit Airlines Logo
12:09 pm - 1:49 am
SDF
-
STI
13h 40m
2 stops
Spirit Airlines Logo
2:46 am - 11:47 am
STI
-
SDF
9h 01m
1 stop
$420Spirit Airlines
Wed, Mar 25 - Mon, Mar 30
Multiple Airlines Logo
9:13 pm - 1:49 am
SDF
-
STI
28h 36m
1 stop
Multiple Airlines Logo
3:28 pm - 11:14 am
STI
-
SDF
19h 46m
2 stops
$443Multiple Airlines
Mon, Mar 30 - Tue, Apr 7
Spirit Airlines Logo
3:33 pm - 1:49 am
SDF
-
STI
10h 16m
1 stop
Spirit Airlines Logo
2:46 am - 11:47 am
STI
-
SDF
9h 01m
1 stop
$453Spirit Airlines
Sun, Mar 29 - Mon, Apr 6
Multiple Airlines Logo
6:06 pm - 2:02 pm
SDF
-
STI
19h 56m
1 stop
Multiple Airlines Logo
3:07 pm - 6:58 pm
STI
-
SDF
27h 51m
1 stop
$482Multiple Airlines
Sat, May 2 - Sun, May 17
Spirit Airlines Logo
12:09 pm - 1:49 am
SDF
-
STI
13h 40m
2 stops
Spirit Airlines Logo
2:46 am - 11:14 am
STI
-
SDF
8h 28m
2 stops
$495Spirit Airlines
Mon, Mar 23 - Sun, Apr 5
Spirit Airlines Logo
12:09 pm - 1:49 am
SDF
-
STI
13h 40m
2 stops
Spirit Airlines Logo
3:28 pm - 11:14 am
STI
-
SDF
19h 46m
2 stops
$498Spirit Airlines
Wed, Mar 25 - Tue, Mar 31
Spirit Airlines Logo
12:09 pm - 1:49 am
SDF
-
STI
13h 40m
2 stops
Spirit Airlines Logo
2:46 am - 11:14 am
STI
-
SDF
32h 28m
3 stops
$534Spirit Airlines
Wed, Mar 25 - Mon, Mar 30
Spirit Airlines Logo
12:09 pm - 2:23 pm
SDF
-
STI
26h 14m
3 stops
Spirit Airlines Logo
3:28 pm - 11:14 am
STI
-
SDF
19h 46m
2 stops
$540Spirit Airlines
Mon, Mar 30 - Tue, Apr 7
Spirit Airlines Logo
3:33 pm - 1:49 am
SDF
-
STI
10h 16m
1 stop
Spirit Airlines Logo
3:28 pm - 11:14 am
STI
-
SDF
19h 46m
2 stops
$541Spirit Airlines
Sun, Mar 29 - Tue, Apr 7

American Airlines flights from Louisville to Santiago de los Caballeros

Our best American Airlines deals on Louisville to Santiago de los Caballeros flight tickets
American Airlines
Aug 11
SDF7:59 amLouisville Intl
12h 49m
2 stops
STI8:48 pmSantiago de los Caballeros
Aug 24
STI7:00 amSantiago de los Caballeros
16h 55m
2 stops
SDF11:55 pmLouisville Intl
$603
American Airlines
May 4
SDF4:25 pmLouisville Intl
19h 58m
2 stops
STI12:23 pmSantiago de los Caballeros
May 17
STI1:32 pmSantiago de los Caballeros
10h 27m
1 stop
SDF11:59 pmLouisville Intl
$608
American Airlines
Aug 11
SDF6:14 amLouisville Intl
6h 17m
1 stop
STI12:31 pmSantiago de los Caballeros
Aug 24
STI7:00 amSantiago de los Caballeros
17h 30m
1 stop
SDF12:30 amLouisville Intl
$612

Spirit Airlines flights from Louisville to Santiago de los Caballeros

Our best Spirit Airlines deals on Louisville to Santiago de los Caballeros flight tickets
Spirit Airlines
Mar 25
SDF12:09 pmLouisville Intl
13h 40m
2 stops
STI1:49 amSantiago de los Caballeros
Mar 30
STI2:46 amSantiago de los Caballeros
9h 01m
1 stop
SDF11:47 amLouisville Intl
$420
Spirit Airlines
Mar 29
SDF3:33 pmLouisville Intl
10h 16m
1 stop
STI1:49 amSantiago de los Caballeros
Apr 6
STI2:46 amSantiago de los Caballeros
9h 01m
1 stop
SDF11:47 amLouisville Intl
$453
Spirit Airlines
Mar 25
SDF12:09 pmLouisville Intl
13h 40m
2 stops
STI1:49 amSantiago de los Caballeros
Mar 31
STI3:28 pmSantiago de los Caballeros
19h 46m
2 stops
SDF11:14 amLouisville Intl
$498

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from Louisville to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleSantiago de los Caballeros

SDF - STI

SDFSTI

Louisville Intl

Mon 3/30

9:13 pm-2:23 pm

1 stop17h 10m

Santiago de los Caballeros

Mon 4/6

2:46 am-11:47 am

1 stop9h 01m

$409

LouisvilleSantiago de los Caballeros

SDF - STI

SDFSTI

Louisville Intl

Wed 3/25

12:09 pm-1:49 am

2 stops13h 40m

Santiago de los Caballeros

Mon 3/30

2:46 am-11:47 am

1 stop9h 01m

$420

LouisvilleSantiago de los Caballeros

SDF - STI

SDFSTI

Louisville Intl

Mon 3/30

9:13 pm-1:49 am

1 stop28h 36m

Santiago de los Caballeros

Tue 4/7

3:28 pm-11:14 am

2 stops19h 46m

$443
Quickest round-trip

LouisvilleSantiago de los Caballeros

SDF - STI

SDFSTI

Louisville Intl

Sun 3/29

3:33 pm-1:49 am

1 stop10h 16m

Santiago de los Caballeros

Mon 4/6

2:46 am-11:47 am

1 stop9h 01m

$453

LouisvilleSantiago de los Caballeros

SDF - STI

SDFSTI

Louisville Intl

Sat 5/2

6:06 pm-2:02 pm

1 stop19h 56m

Santiago de los Caballeros

Sun 5/17

3:07 pm-6:58 pm

1 stop27h 51m

$482

LouisvilleSantiago de los Caballeros

SDF - STI

SDFSTI

Louisville Intl

Mon 3/23

12:09 pm-1:49 am

2 stops13h 40m

Santiago de los Caballeros

Sun 4/5

2:46 am-11:14 am

2 stops8h 28m

$495

LouisvilleSantiago de los Caballeros

SDF - STI

SDFSTI

Louisville Intl

Wed 3/25

12:09 pm-1:49 am

2 stops13h 40m

Santiago de los Caballeros

Tue 3/31

3:28 pm-11:14 am

2 stops19h 46m

$498

LouisvilleSantiago de los Caballeros

SDF - STI

SDFSTI

Louisville Intl

Wed 3/25

12:09 pm-1:49 am

2 stops13h 40m

Santiago de los Caballeros

Mon 3/30

2:46 am-11:14 am

3 stops32h 28m

$534

LouisvilleSantiago de los Caballeros

SDF - STI

SDFSTI

Louisville Intl

Mon 3/30

12:09 pm-2:23 pm

3 stops26h 14m

Santiago de los Caballeros

Tue 4/7

3:28 pm-11:14 am

2 stops19h 46m

$540

LouisvilleSantiago de los Caballeros

SDF - STI

SDFSTI

Louisville Intl

Sun 3/29

3:33 pm-1:49 am

1 stop10h 16m

Santiago de los Caballeros

Tue 4/7

3:28 pm-11:14 am

2 stops19h 46m

$541

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Louisville to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Louisville to Santiago de los Caballeros flights?

You could potentially save up to 11% on your flight if you consider stops on a Louisville to Santiago de los Caballeros flight.

When to book flights from Louisville to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Santiago de los Caballeros (SDF to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Santiago de los Caballeros

Fastest flight time

8h 55m

Direct flights

None
The fastest flight from Louisville to Santiago de los Caballeros takes 8h 55m
There are no direct flights from Louisville to Santiago de los Caballeros. There are no popular flight routes from Louisville to Santiago de los Caballeros.
Search flight deals

  • How far is Louisville Intl to Santiago de los Caballeros by plane?

    A flight from Louisville Intl to Santiago de los Caballeros will travel around 1580.6 mi. Flights usually cover this in 8h 55m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Louisville Intl Airport to Santiago de los Caballeros Airport?

    Prices for flights from Louisville Intl Airport to Santiago de los Caballeros Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents you'll need for your trip to Santiago de los Caballeros Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago de los Caballeros Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Louisville to Santiago de los Caballeros?

Best airlines flying from Louisville to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Louisville to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $514Free CancellationRating
7.1
11,419 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Santiago de los Caballeros?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago de los Caballeros from Louisville.

Can I find flights from Louisville to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago de los Caballeros from Louisville with this policy.

How can momondo help me find flights from Louisville to Santiago de los Caballeros?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Louisville to Santiago de los Caballeros.

I’m not ready to book a flight from Louisville to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Louisville to Santiago de los Caballeros flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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