Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Louisville to the Cayman Islands from $271

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to the Cayman Islands departing on 2/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Louisville to the Cayman Islands

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 12:00 pm
SDF
-
GCM
7h 00m
1 stop
Delta Logo
1:19 pm - 12:20 am
GCM
-
SDF
10h 01m
1 stop
$419Delta
Thu, Apr 30 - Thu, May 7
Delta Logo
7:05 am - 11:47 am
SDF
-
GCM
5h 42m
1 stop
Delta Logo
2:30 pm - 11:57 pm
GCM
-
SDF
8h 27m
1 stop
$459Delta
Wed, Mar 11 - Sat, Mar 14
American Airlines Logo
11:02 am - 7:15 pm
SDF
-
GCM
9h 13m
2 stops
American Airlines Logo
5:16 pm - 10:04 am
GCM
-
SDF
15h 48m
1 stop
$464American Airlines
Wed, Mar 11 - Sat, Mar 14
Delta Logo
7:05 am - 12:00 pm
SDF
-
GCM
5h 55m
1 stop
Delta Logo
1:19 pm - 12:20 am
GCM
-
SDF
10h 01m
1 stop
$469Delta
Fri, May 1 - Sun, May 10
American Airlines Logo
7:52 pm - 1:10 pm
SDF
-
GCM
18h 18m
2 stops
American Airlines Logo
2:10 pm - 8:38 am
GCM
-
SDF
17h 28m
2 stops
$474American Airlines
Fri, May 1 - Sat, May 9
American Airlines Logo
7:00 am - 7:15 pm
SDF
-
GCM
13h 15m
2 stops
American Airlines Logo
7:45 am - 8:51 pm
GCM
-
SDF
12h 06m
2 stops
$508American Airlines
Wed, Mar 11 - Sat, Mar 14
Delta Logo
7:05 am - 12:00 pm
SDF
-
GCM
5h 55m
1 stop
Delta Logo
1:19 pm - 9:19 pm
GCM
-
SDF
7h 00m
1 stop
$512Delta
Sat, May 2 - Thu, May 7
American Airlines Logo
5:00 am - 11:28 am
SDF
-
GCM
7h 28m
1 stop
American Airlines Logo
2:45 pm - 11:19 pm
GCM
-
SDF
7h 34m
1 stop
$515American Airlines
Wed, Jun 3 - Tue, Jun 9
American Airlines Logo
6:01 am - 4:11 pm
SDF
-
GCM
11h 10m
2 stops
American Airlines Logo
12:33 pm - 10:27 pm
GCM
-
SDF
8h 54m
1 stop
$520American Airlines
Wed, Jun 3 - Tue, Jun 9
American Airlines Logo
8:08 pm - 11:28 am
SDF
-
GCM
16h 20m
1 stop
American Airlines Logo
12:51 pm - 11:07 pm
GCM
-
SDF
9h 16m
1 stop
$537American Airlines
Sat, May 30 - Sat, Jun 6

Delta flights from Louisville to Cayman Islands

Our best Delta deals on Louisville to Cayman Islands flight tickets
Delta
Apr 30
SDF6:00 amLouisville Intl
7h 00m
1 stop
GCM12:00 pmGeorge Town Owen Roberts Intl
May 7
GCM1:19 pmGeorge Town Owen Roberts Intl
10h 01m
1 stop
SDF12:20 amLouisville Intl
$419
Delta
Mar 11
SDF7:05 amLouisville Intl
5h 42m
1 stop
GCM11:47 amGeorge Town Owen Roberts Intl
Mar 14
GCM2:30 pmGeorge Town Owen Roberts Intl
8h 27m
1 stop
SDF11:57 pmLouisville Intl
$459
Delta
May 1
SDF7:05 amLouisville Intl
5h 55m
1 stop
GCM12:00 pmGeorge Town Owen Roberts Intl
May 10
GCM1:19 pmGeorge Town Owen Roberts Intl
10h 01m
1 stop
SDF12:20 amLouisville Intl
$469

American Airlines flights from Louisville to Cayman Islands

Our best American Airlines deals on Louisville to Cayman Islands flight tickets
American Airlines
Mar 11
SDF7:00 amLouisville Intl
13h 15m
2 stops
GCM7:15 pmGeorge Town Owen Roberts Intl
Mar 14
GCM2:44 pmGeorge Town Owen Roberts Intl
7h 36m
1 stop
SDF11:20 pmLouisville Intl
$464
American Airlines
May 1
SDF7:52 pmLouisville Intl
18h 18m
2 stops
GCM1:10 pmGeorge Town Owen Roberts Intl
May 9
GCM2:10 pmGeorge Town Owen Roberts Intl
17h 28m
2 stops
SDF8:38 amLouisville Intl
$474
American Airlines
Mar 11
SDF7:00 amLouisville Intl
13h 15m
2 stops
GCM7:15 pmGeorge Town Owen Roberts Intl
Mar 14
GCM7:45 amGeorge Town Owen Roberts Intl
12h 06m
2 stops
SDF8:51 pmLouisville Intl
$508

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 14, 2026.
Use the filters below to find and compare flights from Louisville to the Cayman Islands that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Thu 4/30

6:00 am-12:00 pm

1 stop7h 00m

George Town Owen Roberts Intl

Thu 5/7

1:19 pm-12:20 am

1 stop10h 01m

$419

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Wed 3/11

7:05 am-11:47 am

1 stop5h 42m

George Town Owen Roberts Intl

Sat 3/14

2:30 pm-11:57 pm

1 stop8h 27m

$459

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Wed 3/11

11:02 am-7:15 pm

2 stops9h 13m

George Town Owen Roberts Intl

Sat 3/14

5:16 pm-10:04 am

1 stop15h 48m

$464

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Fri 5/1

7:05 am-12:00 pm

1 stop5h 55m

George Town Owen Roberts Intl

Sun 5/10

1:19 pm-12:20 am

1 stop10h 01m

$469

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Fri 5/1

7:52 pm-1:10 pm

2 stops18h 18m

George Town Owen Roberts Intl

Sat 5/9

2:10 pm-8:38 am

2 stops17h 28m

$474

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Wed 3/11

7:00 am-7:15 pm

2 stops13h 15m

George Town Owen Roberts Intl

Sat 3/14

7:45 am-8:51 pm

2 stops12h 06m

$508

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Sat 5/2

7:05 am-12:00 pm

1 stop5h 55m

George Town Owen Roberts Intl

Thu 5/7

1:19 pm-9:19 pm

1 stop7h 00m

$512

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Wed 6/3

5:00 am-11:28 am

1 stop7h 28m

George Town Owen Roberts Intl

Tue 6/9

2:45 pm-11:19 pm

1 stop7h 34m

$515

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Wed 6/3

6:01 am-4:11 pm

2 stops11h 10m

George Town Owen Roberts Intl

Tue 6/9

12:33 pm-10:27 pm

1 stop8h 54m

$520

LouisvilleGeorge Town

SDF - GCM

SDFGCM

Louisville Intl

Sat 5/30

8:08 pm-11:28 am

1 stop16h 20m

George Town Owen Roberts Intl

Sat 6/6

12:51 pm-11:07 pm

1 stop9h 16m

$537

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

See travel insights to the Cayman Islands from

How to get the cheapest flight ticket from Louisville to Cayman Islands

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Cayman Islands?

If you aren’t able to travel to Cayman Islands during the month of September, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $459.

Cheap Louisville to Cayman Islands flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Cayman Islands

Fastest flight time

5h 25m

Direct flights

None
The fastest flight from Louisville to Cayman Islands takes 5h 25m
There are no direct flights from Louisville to Cayman Islands. There are no popular flight routes from Louisville to Cayman Islands.
Search flight deals

  • When did momondo last update prices for flights from Louisville Intl Airport to Cayman Islands?

    Prices for flights from Louisville Intl Airport to Cayman Islands refresh daily.

  • How many operators does momondo search for flights from Louisville Intl Airport to Cayman Islands?

  • How old do you have to be to fly from Louisville Intl Airport to Cayman Islands?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Cayman Islands.

  • What documentation or ID do you need to fly to Cayman Islands?

    The necessary travel and health documents for your Cayman Islands trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Louisville to Cayman Islands

Compare and see reviews for airlines that fly from Louisville to Cayman Islands with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $190Free CancellationRating
7.9
8,203 reviews
Search Delta flights
American AirlinesPriceFrom $367Free CancellationRating
7.2
11,288 reviews
Search American Airlines flights
United AirlinesPriceFrom $406Free CancellationRating
7.4
9,289 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Cayman Islands?

It is quick and easy to find Louisville to Cayman Islands flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Cayman Islands that suits you.

Can I find flights from Louisville to Cayman Islands with flexible booking policies on momondo?

All flight searches from Louisville to Cayman Islands on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Louisville to Cayman Islands?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Louisville to Cayman Islands.

I’m not ready to book a flight from Louisville to Cayman Islands right now. Can momondo alert me if prices change?

Price alerts on flights to Cayman Islands from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Cayman Islands trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Mon 3/16
Mon 3/23
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the Cayman Islands

Popular cities in the Cayman Islands

Popular flights according to clicks in the last 7 days on momondo
Flights to George Townfrom $222
Flights to Cayman Bracfrom $326
Flights to Little Caymanfrom $319