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Cheap flights from Louisville to the Cayman Islands from $432

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to the Cayman Islands departing on 2/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Louisville to the Cayman Islands

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 12:40 pmSDF  Louisville Intl-GCM George Town Owen Roberts Intl
6h 40m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:05 pm - 12:02 amGCM  George Town Owen Roberts Intl-SDF Louisville Intl
9h 57m1 stop Atlanta Hartsfield-Jackson
$432Delta
Tue, Feb 9 - Sat, Feb 13
American Airlines Logo
7:11 am - 2:30 pmSDF  Louisville Intl-GCM George Town Owen Roberts Intl
7h 19m1 stop Dallas/Fort Worth
American Airlines Logo
3:45 pm - 11:56 pmGCM  George Town Owen Roberts Intl-SDF Louisville Intl
8h 11m1 stop Miami
$453American Airlines
Sat, Nov 14 - Sat, Nov 21
American Airlines Logo
6:18 am - 11:27 amSDF  Louisville Intl-GCM George Town Owen Roberts Intl
6h 09m1 stop Charlotte Douglas
American Airlines Logo
8:00 am - 11:39 pmGCM  George Town Owen Roberts Intl-SDF Louisville Intl
14h 39m1 stop Miami
$453American Airlines
Fri, Oct 2 - Fri, Oct 9
American Airlines Logo
7:30 am - 7:58 pmSDF  Louisville Intl-GCM George Town Owen Roberts Intl
12h 28m2 stops Philadelphia Miami
American Airlines Logo
8:15 am - 11:56 pmGCM  George Town Owen Roberts Intl-SDF Louisville Intl
15h 41m1 stop Miami
$458American Airlines
Sat, Nov 14 - Sat, Nov 21
American Airlines Logo
7:30 am - 7:58 pmSDF  Louisville Intl-GCM George Town Owen Roberts Intl
12h 28m2 stops Philadelphia Miami
American Airlines Logo
8:15 am - 5:26 pmGCM  George Town Owen Roberts Intl-SDF Louisville Intl
9h 11m2 stops Miami Charlotte Douglas
$458American Airlines
Sat, Nov 14 - Sat, Nov 21
United Airlines Logo
7:05 am - 4:30 pmSDF  Louisville Intl-GCM George Town Owen Roberts Intl
9h 25m1 stop Houston George Bush Intcntl
United Airlines Logo
5:45 pm - 8:55 pmGCM  George Town Owen Roberts Intl-SDF Louisville Intl
27h 10m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
$613United Airlines
Sun, Dec 13 - Wed, Dec 16
United Airlines Logo
7:05 am - 4:30 pmSDF  Louisville Intl-GCM George Town Owen Roberts Intl
9h 25m1 stop Houston George Bush Intcntl
United Airlines Logo
5:45 pm - 9:48 pmGCM  George Town Owen Roberts Intl-SDF Louisville Intl
28h 03m1 stop Houston George Bush Intcntl
$622United Airlines
Sun, Dec 13 - Wed, Dec 16
United Airlines Logo
7:05 am - 4:30 pmSDF  Louisville Intl-GCM George Town Owen Roberts Intl
9h 25m1 stop Houston George Bush Intcntl
United Airlines Logo
5:45 pm - 8:55 pmGCM  George Town Owen Roberts Intl-SDF Louisville Intl
27h 10m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
$633United Airlines
Sun, Dec 13 - Wed, Dec 16
Delta Logo
6:36 am - 2:15 pmSDF  Louisville Intl-GCM George Town Owen Roberts Intl
7h 39m1 stop Minneapolis St Paul
Delta Logo
3:50 pm - 12:02 amGCM  George Town Owen Roberts Intl-SDF Louisville Intl
8h 12m1 stop Atlanta Hartsfield-Jackson
$2,140Delta
Sat, Dec 26 - Sat, Jan 2
Delta Logo
6:36 am - 2:15 pmSDF  Louisville Intl-GCM George Town Owen Roberts Intl
7h 39m1 stop Minneapolis St Paul
Delta Logo
1:00 pm - 12:02 amGCM  George Town Owen Roberts Intl-SDF Louisville Intl
11h 02m2 stops Detroit Metropolitan Wayne County Atlanta Hartsfield-Jackson
$2,732Delta
Sat, Dec 26 - Sat, Jan 2

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American Airlines flights from Louisville to Cayman Islands

Our best American Airlines deals on Louisville to Cayman Islands flight tickets
American Airlines
Oct 2
SDF6:18 amLouisville Intl
6h 09m
1 stop
GCM11:27 amGeorge Town Owen Roberts Intl
Oct 9
GCM8:00 amGeorge Town Owen Roberts Intl
14h 39m
1 stop
SDF11:39 pmLouisville Intl
$453
American Airlines
Oct 2
SDF4:48 pmLouisville Intl
19h 39m
2 stops
GCM11:27 amGeorge Town Owen Roberts Intl
Oct 9
GCM8:00 amGeorge Town Owen Roberts Intl
15h 08m
2 stops
SDF12:08 amLouisville Intl
$458
American Airlines
Sep 26
SDF2:53 pmLouisville Intl
21h 37m
1 stop
GCM11:30 amGeorge Town Owen Roberts Intl
Oct 3
GCM12:36 pmGeorge Town Owen Roberts Intl
20h 07m
2 stops
SDF9:43 amLouisville Intl
$465

United Airlines flights from Louisville to Cayman Islands

Our best United Airlines deals on Louisville to Cayman Islands flight tickets
United Airlines
Dec 13
SDF7:05 amLouisville Intl
9h 25m
1 stop
GCM4:30 pmGeorge Town Owen Roberts Intl
Dec 16
GCM5:45 pmGeorge Town Owen Roberts Intl
27h 10m
2 stops
SDF8:55 pmLouisville Intl
$613
United Airlines
Dec 13
SDF7:05 amLouisville Intl
9h 25m
1 stop
GCM4:30 pmGeorge Town Owen Roberts Intl
Dec 16
GCM5:45 pmGeorge Town Owen Roberts Intl
28h 03m
1 stop
SDF9:48 pmLouisville Intl
$622
United Airlines
Dec 13
SDF7:05 amLouisville Intl
9h 25m
1 stop
GCM4:30 pmGeorge Town Owen Roberts Intl
Dec 16
GCM5:45 pmGeorge Town Owen Roberts Intl
27h 10m
2 stops
SDF8:55 pmLouisville Intl
$633

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 13, 2026.
Use the filters below to find and compare flights from Louisville to the Cayman Islands that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleGeorge Town

SDF Louisville Intl - GCM George Town Owen Roberts Intl

SDFGCM

Louisville Intl

Tue 2/9

6:00 am-12:40 pm

1 stop6h 40m

George Town Owen Roberts Intl

Sat 2/13

2:05 pm-12:02 am

1 stop9h 57m

$432
Quickest round-trip

LouisvilleGeorge Town

SDF Louisville Intl - GCM George Town Owen Roberts Intl

SDFGCM

Louisville Intl

Sat 11/14

7:11 am-2:30 pm

1 stop7h 19m

George Town Owen Roberts Intl

Sat 11/21

3:45 pm-11:56 pm

1 stop8h 11m

$453

LouisvilleGeorge Town

SDF Louisville Intl - GCM George Town Owen Roberts Intl

SDFGCM

Louisville Intl

Fri 10/2

6:18 am-11:27 am

1 stop6h 09m

George Town Owen Roberts Intl

Fri 10/9

8:00 am-11:39 pm

1 stop14h 39m

$453

LouisvilleGeorge Town

SDF Louisville Intl - GCM George Town Owen Roberts Intl

SDFGCM

Louisville Intl

Sat 11/14

7:30 am-7:58 pm

2 stops12h 28m

George Town Owen Roberts Intl

Sat 11/21

8:15 am-11:56 pm

1 stop15h 41m

$458

LouisvilleGeorge Town

SDF Louisville Intl - GCM George Town Owen Roberts Intl

SDFGCM

Louisville Intl

Sat 11/14

7:30 am-7:58 pm

2 stops12h 28m

George Town Owen Roberts Intl

Sat 11/21

8:15 am-5:26 pm

2 stops9h 11m

$458

LouisvilleGeorge Town

SDF Louisville Intl - GCM George Town Owen Roberts Intl

SDFGCM

Louisville Intl

Sun 12/13

7:05 am-4:30 pm

1 stop9h 25m

George Town Owen Roberts Intl

Wed 12/16

5:45 pm-8:55 pm

2 stops27h 10m

$613

LouisvilleGeorge Town

SDF Louisville Intl - GCM George Town Owen Roberts Intl

SDFGCM

Louisville Intl

Sun 12/13

7:05 am-4:30 pm

1 stop9h 25m

George Town Owen Roberts Intl

Wed 12/16

5:45 pm-9:48 pm

1 stop28h 03m

$622

LouisvilleGeorge Town

SDF Louisville Intl - GCM George Town Owen Roberts Intl

SDFGCM

Louisville Intl

Sun 12/13

7:05 am-4:30 pm

1 stop9h 25m

George Town Owen Roberts Intl

Wed 12/16

5:45 pm-8:55 pm

2 stops27h 10m

$633

LouisvilleGeorge Town

SDF Louisville Intl - GCM George Town Owen Roberts Intl

SDFGCM

Louisville Intl

Sat 12/26

6:36 am-2:15 pm

1 stop7h 39m

George Town Owen Roberts Intl

Sat 1/2

3:50 pm-12:02 am

1 stop8h 12m

$2,140

LouisvilleGeorge Town

SDF Louisville Intl - GCM George Town Owen Roberts Intl

SDFGCM

Louisville Intl

Sat 12/26

6:36 am-2:15 pm

1 stop7h 39m

George Town Owen Roberts Intl

Sat 1/2

1:00 pm-12:02 am

2 stops11h 02m

$2,732

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to the Cayman Islands from

How to get the cheapest flight ticket from Louisville to Cayman Islands

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Cayman Islands?

If you aren’t able to travel to Cayman Islands during the month of November, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $459.

Cheap Louisville to Cayman Islands flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Cayman Islands

Fastest flight time

5h 25m

Direct flights

None
The fastest flight from Louisville to Cayman Islands takes 5h 25m
There are no direct flights from Louisville to Cayman Islands. There are no popular flight routes from Louisville to Cayman Islands.
Search flight deals

Frequently asked questions about flying from Louisville to the Cayman Islands

  • When did momondo last update prices for flights from Louisville Intl Airport to Cayman Islands?

    Prices for flights from Louisville Intl Airport to Cayman Islands refresh daily.

  • How many operators does momondo search for flights from Louisville Intl Airport to Cayman Islands?

  • How old do you have to be to fly from Louisville Intl Airport to Cayman Islands?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Cayman Islands.

  • What documentation or ID do you need to fly to Cayman Islands?

    The necessary travel and health documents for your Cayman Islands trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Louisville to Cayman Islands

Compare and see reviews for airlines that fly from Louisville to Cayman Islands with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $409Free CancellationRating
7.8
8,502 reviews
Search Delta flights
American AirlinesPriceFrom $508Free CancellationRating
7.1
11,923 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Cayman Islands?

It is quick and easy to find Louisville to Cayman Islands flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Cayman Islands that suits you.

Can I find flights from Louisville to Cayman Islands with flexible booking policies on momondo?

All flight searches from Louisville to Cayman Islands on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Louisville to Cayman Islands?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Louisville to Cayman Islands.

I’m not ready to book a flight from Louisville to Cayman Islands right now. Can momondo alert me if prices change?

Price alerts on flights to Cayman Islands from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Find better results for your trip to the Cayman Islands

Popular cities in the Cayman Islands

Popular flights according to clicks in the last 7 days on momondo
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Flights to Little Caymanfrom $366