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Cheap flights from Medellín Jose Maria Cordova Intl Airport to Santiago from $170

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Medellín Jose Maria Cordova Intl Airport to Santiago departing on 12/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Medellín Jose Maria Cordova Intl Airport to Santiago

Cheap round-trip flights

JetSMART Logo
6:09 pm - 4:01 amMDE-SCL
8h 52m1 stop
JetSMART Logo
4:51 am - 5:20 pmSCL-MDE
13h 29m1 stop
$339JetSMART
Find Deal
mié., ago. 27 - mié., sep. 3
JetSMART Logo
2:00 pm - 4:17 amMDE-SCL
13h 17m1 stop
JetSMART Logo
3:33 pm - 11:42 pmSCL-MDE
10h 09m1 stop
$346JetSMART
Find Deal
lun., sep. 1 - lun., sep. 8
Logo
4:37 pm - 4:17 amMDE-SCL
10h 40m1 stop
Logo
9:40 pm - 5:55 pmSCL-MDE
21h 15m2 stops
$352
Find Deal
mié., ago. 27 - mié., sep. 3
Logo
4:37 pm - 4:17 amMDE-SCL
10h 40m1 stop
Logo
12:24 am - 8:17 amSCL-MDE
8h 53m1 stop
$357
Find Deal
mié., ago. 27 - mar., sep. 2
Avianca Logo
7:58 am - 10:30 pmMDE-SCL
13h 32m1 stop
Avianca Logo
6:10 am - 4:12 pmSCL-MDE
11h 02m1 stop
$379Avianca
Find Deal
dom., ago. 10 - vie., ago. 22
LATAM Airlines Logo
3:55 am - 3:00 pmMDE-SCL
9h 05m1 stop
LATAM Airlines Logo
11:40 am - 2:50 amSCL-MDE
17h 10m1 stop
$381LATAM Airlines
Find Deal
jue., sep. 11 - sáb., sep. 27
Copa Airlines Logo
6:40 am - 10:44 pmMDE-SCL
15h 04m1 stop
Copa Airlines Logo
12:24 am - 2:45 pmSCL-MDE
15h 21m1 stop
$385Copa Airlines
Find Deal
mié., ago. 13 - vie., ago. 29
Copa Airlines Logo
6:37 am - 8:20 pmMDE-SCL
11h 43m1 stop
Copa Airlines Logo
1:24 am - 8:17 amSCL-MDE
8h 53m1 stop
$386Copa Airlines
Find Deal
vie., sep. 12 - mié., sep. 24
Avianca Logo
6:57 pm - 5:15 amMDE-SCL
8h 18m1 stop
Avianca Logo
6:55 am - 1:19 pmSCL-MDE
8h 24m1 stop
$388Avianca
Find Deal
vie., oct. 17 - sáb., nov. 15
LATAM Airlines Logo
6:20 pm - 3:30 amMDE-SCL
8h 10m1 stop
LATAM Airlines Logo
8:10 am - 7:41 pmSCL-MDE
13h 31m2 stops
$400LATAM Airlines
Find Deal
mié., ago. 20 - vie., sep. 19

LATAM Airlines flights from Medellín Jose Maria Cordova Intl Airport to Santiago

Our best LATAM Airlines deals on Medellín Jose Maria Cordova Intl Airport to Santiago flight tickets
LATAM Airlines
Sep 11
MDE3:55 amMedellín Jose Maria Cordova Intl
9h 05m
1 stop
SCL3:00 pmSantiago Arturo Merino Benitez
Sep 27
SCL11:40 amSantiago Arturo Merino Benitez
17h 10m
1 stop
MDE2:50 amMedellín Jose Maria Cordova Intl
$381
Find similar
LATAM Airlines
Aug 20
MDE6:20 pmMedellín Jose Maria Cordova Intl
8h 10m
1 stop
SCL3:30 amSantiago Arturo Merino Benitez
Sep 19
SCL8:10 amSantiago Arturo Merino Benitez
13h 31m
2 stops
MDE7:41 pmMedellín Jose Maria Cordova Intl
$400
Find similar
LATAM Airlines
Oct 12
MDE3:55 amMedellín Jose Maria Cordova Intl
8h 30m
1 stop
SCL2:25 pmSantiago Arturo Merino Benitez
Nov 10
SCL4:35 amSantiago Arturo Merino Benitez
13h 40m
1 stop
MDE4:15 pmMedellín Jose Maria Cordova Intl
$401
Find similar

Avianca flights from Medellín Jose Maria Cordova Intl Airport to Santiago

Our best Avianca deals on Medellín Jose Maria Cordova Intl Airport to Santiago flight tickets
Avianca
Aug 10
MDE7:58 amMedellín Jose Maria Cordova Intl
13h 32m
1 stop
SCL10:30 pmSantiago Arturo Merino Benitez
Aug 22
SCL6:10 amSantiago Arturo Merino Benitez
11h 02m
1 stop
MDE4:12 pmMedellín Jose Maria Cordova Intl
$379
Find similar
Avianca
Oct 17
MDE6:57 pmMedellín Jose Maria Cordova Intl
8h 18m
1 stop
SCL5:15 amSantiago Arturo Merino Benitez
Nov 15
SCL6:55 amSantiago Arturo Merino Benitez
8h 24m
1 stop
MDE1:19 pmMedellín Jose Maria Cordova Intl
$388
Find similar
Avianca
Oct 13
MDE6:57 pmMedellín Jose Maria Cordova Intl
8h 18m
1 stop
SCL5:15 amSantiago Arturo Merino Benitez
Nov 14
SCL6:35 amSantiago Arturo Merino Benitez
8h 44m
1 stop
MDE1:19 pmMedellín Jose Maria Cordova Intl
$391
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Medellín Jose Maria Cordova Intl Airport to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated julio 31, 2025.
Use the filters below to find and compare flights from Medellín Jose Maria Cordova Intl Airport to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

mié. 8/27

6:09 pm-4:01 am

1 stop8h 52m

Santiago Arturo Merino Benitez

mié. 9/3

4:51 am-5:20 pm

1 stop13h 29m

$339

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

lun. 9/1

2:00 pm-4:17 am

1 stop13h 17m

Santiago Arturo Merino Benitez

lun. 9/8

3:33 pm-11:42 pm

1 stop10h 09m

$346

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

mié. 8/27

4:37 pm-4:17 am

1 stop10h 40m

Santiago Arturo Merino Benitez

mié. 9/3

9:40 pm-5:55 pm

2 stops21h 15m

$352

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

mié. 8/27

4:37 pm-4:17 am

1 stop10h 40m

Santiago Arturo Merino Benitez

mar. 9/2

12:24 am-8:17 am

1 stop8h 53m

$357

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

dom. 8/10

7:58 am-10:30 pm

1 stop13h 32m

Santiago Arturo Merino Benitez

vie. 8/22

6:10 am-4:12 pm

1 stop11h 02m

$379

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

jue. 9/11

3:55 am-3:00 pm

1 stop9h 05m

Santiago Arturo Merino Benitez

sáb. 9/27

11:40 am-2:50 am

1 stop17h 10m

$381

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

mié. 8/13

6:40 am-10:44 pm

1 stop15h 04m

Santiago Arturo Merino Benitez

vie. 8/29

12:24 am-2:45 pm

1 stop15h 21m

$385

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

vie. 9/12

6:37 am-8:20 pm

1 stop11h 43m

Santiago Arturo Merino Benitez

mié. 9/24

1:24 am-8:17 am

1 stop8h 53m

$386

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

vie. 10/17

6:57 pm-5:15 am

1 stop8h 18m

Santiago Arturo Merino Benitez

sáb. 11/15

6:55 am-1:19 pm

1 stop8h 24m

$388

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

mié. 8/20

6:20 pm-3:30 am

1 stop8h 10m

Santiago Arturo Merino Benitez

vie. 9/19

8:10 am-7:41 pm

2 stops13h 31m

$400

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Medellín Jose Maria Cordova Intl Airport to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Medellín Jose Maria Cordova Intl Airport and Santiago?

What is the cheapest month to fly to Santiago?

In general, October is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $333. If you don’t want to visit Santiago in October, then you should wait until November to fly from Medellín Jose Maria Cordova Intl Airport, when ticket prices are also cheap, with an average price of $344.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Tuesday when prices can be found for as low as $297. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Sunday is $495.

What is the cheapest time of day to depart on your flight to Santiago?

In the afternoon is the cheapest time of day to fly from Medellín Jose Maria Cordova Intl Airport to Santiago when you can find flight prices for as low as $449. Flying to Santiago in the afternoon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Santiago, so prices are often more expensive at around $518 per ticket.

What is the cheapest Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez flight route?

Fly from Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez for the best Medellín Jose Maria Cordova Intl - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Medellín Jose Maria Cordova Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $369 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Medellín Jose Maria Cordova Intl Airport for as low as $317 on momondo.

What cabin class options are available on Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez flights?

There are 1 cabin classes available to choose from on Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Medellín Jose Maria Cordova Intl Airport to Santiago flight prices changed over time?

As of July 2025, prices for Medellín Jose Maria Cordova Intl Airport to Santiago flights are approximately 11% cheaper when compared to flights at the same time last year.

When to book flights from Medellín Jose Maria Cordova Intl Airport to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Medellín Jose Maria Cordova Intl Airport to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Medellín Jose Maria Cordova Intl Airport to Santiago (MDE to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medellín Jose Maria Cordova Intl Airport to Santiago

Best Price Found

$170

Fastest flight time

6h 08m

Direct flights

Thu

Airports in Santiago

1 airport
The best one-way flight to Santiago from Medellín Jose Maria Cordova Intl Airport in the past 72 hours is $170. The best round-trip flight deal from Medellín Jose Maria Cordova Intl Airport to Santiago found on momondo in the last 72 hours is $339.
The fastest flight from Medellín Jose Maria Cordova Intl Airport to Santiago takes 6h 08m
Direct flights go from Medellín Jose Maria Cordova Intl Airport to Santiago on Thursday. The only airline offering direct flights is JetSMART.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)
Search flight deals

  • How far is Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez by plane?

    Medellín Jose Maria Cordova Intl and Santiago Arturo Merino Benitez are 2752.8 mi apart from one another. Typically, this will take 8h 10m by plane in normal conditions.

  • When did momondo last update prices for flights from Medellín Jose Maria Cordova Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Medellín Jose Maria Cordova Intl Airport to Santiago Arturo Merino Benitez Airport are updated daily.

  • How many operators does momondo search for flights from Medellín Jose Maria Cordova Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Medellín Jose Maria Cordova Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Medellín Jose Maria Cordova Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Medellín Jose Maria Cordova Intl Airport to Santiago?

  • What is the most popular airline from Medellín Jose Maria Cordova Intl Airport to Santiago?

Best airlines flying from Medellín Jose Maria Cordova Intl Airport to Santiago

Compare and see reviews for airlines that fly from Medellín Jose Maria Cordova Intl Airport to Santiago with momondo
Airline
Rating
Free Cancellation
Price
JetSMARTPriceFrom $177Free CancellationRating
6.5
211 reviews
Search JetSMART flights
LATAM AirlinesPriceFrom $256Free CancellationRating
7.5
1,822 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $303Free CancellationRating
7.5
1,493 reviews
Search Copa Airlines flights
AviancaPriceFrom $354Free CancellationRating
6.7
2,388 reviews
Search Avianca flights

Traveling to a place near Santiago?

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