Cheap flights from Medellín Jose Maria Cordova Intl Airport to Santiago from $221

1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Medellín Jose Maria Cordova Intl Airport to Santiago

Cheap round-trip flights

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JetSMART Logo
8:31 am - 5:05 amMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
18h 34m1 stop Lima J Chavez Intl
JetSMART Logo
12:32 pm - 4:46 pmSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
30h 14m1 stop Lima J Chavez Intl
$369JetSMART
Sat, Dec 26 - Thu, Feb 25
JetSMART Logo
8:31 am - 10:55 amMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
24h 24m1 stop Lima J Chavez Intl
JetSMART Logo
12:32 pm - 4:46 pmSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
30h 14m1 stop Lima J Chavez Intl
$369JetSMART
Tue, Dec 8 - Sun, Mar 7
JetSMART Logo
8:31 am - 5:05 amMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
18h 34m1 stop Lima J Chavez Intl
JetSMART Logo
6:07 am - 4:46 pmSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
12h 39m1 stop Lima J Chavez Intl
$369JetSMART
Sat, Dec 12 - Thu, Mar 4
Multiple Airlines Logo
5:01 pm - 1:13 amMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
6h 12mnonstop
Multiple Airlines Logo
4:36 pm - 9:20 pmSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
30h 44m1 stop Cali Alfonso B. Aragon Intl
$425Multiple Airlines
Sat, Jan 30 - Fri, Mar 12
Multiple Airlines Logo
5:00 am - 3:10 pmMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
32h 10m2 stops Cali Alfonso B. Aragon Intl Antofagasta Cerro Moreno
Multiple Airlines Logo
2:13 am - 6:28 amSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
6h 15mnonstop
$425Multiple Airlines
Fri, Feb 5 - Wed, Mar 17
Multiple Airlines Logo
7:30 am - 11:36 pmMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
14h 06m2 stops Cali Alfonso B. Aragon Intl Antofagasta Cerro Moreno
Multiple Airlines Logo
2:13 am - 6:28 amSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
6h 15mnonstop
$425Multiple Airlines
Wed, Feb 3 - Sun, Mar 14
LATAM Airlines Logo
6:10 pm - 4:20 amMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
9h 10m1 stop Lima J Chavez Intl
LATAM Airlines Logo
8:40 am - 4:25 pmSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
8h 45m1 stop Lima J Chavez Intl
$472LATAM Airlines
Wed, Apr 7 - Thu, Apr 15
LATAM Airlines Logo
10:55 am - 1:50 amMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
13h 55m2 stops Bogotá El Dorado Lima J Chavez Intl
LATAM Airlines Logo
6:40 am - 4:25 pmSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
10h 45m1 stop Lima J Chavez Intl
$478LATAM Airlines
Wed, Apr 7 - Thu, Apr 15
Avianca Logo
4:30 am - 3:10 pmMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
8h 40m1 stop Bogotá El Dorado
Avianca Logo
7:30 am - 4:50 pmSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
11h 20m1 stop Bogotá El Dorado
$652Avianca
Fri, Jan 29 - Thu, Mar 18
Avianca Logo
4:10 pm - 5:45 amMDE  Medellín Jose Maria Cordova Intl-SCL Santiago Arturo Merino Benitez
11h 35m1 stop Bogotá El Dorado
Avianca Logo
4:15 pm - 11:20 pmSCL  Santiago Arturo Merino Benitez-MDE Medellín Jose Maria Cordova Intl
9h 05m1 stop Bogotá El Dorado
$680Avianca
Tue, Nov 24 - Wed, Dec 2

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JetSMART flights from Medellín Jose Maria Cordova Intl Airport to Santiago

Our best JetSMART deals on Medellín Jose Maria Cordova Intl Airport to Santiago flight tickets
JetSMART
Dec 8
MDE8:31 amMedellín Jose Maria Cordova Intl
24h 24m
1 stop
SCL10:55 amSantiago Arturo Merino Benitez
Mar 7
SCL12:32 pmSantiago Arturo Merino Benitez
30h 14m
1 stop
MDE4:46 pmMedellín Jose Maria Cordova Intl
$369
JetSMART
Dec 8
MDE5:36 pmMedellín Jose Maria Cordova Intl
15h 19m
1 stop
SCL10:55 amSantiago Arturo Merino Benitez
Mar 6
SCL2:13 amSantiago Arturo Merino Benitez
6h 15m
MDE6:28 amMedellín Jose Maria Cordova Intl
$378
JetSMART
Dec 26
MDE5:01 pmMedellín Jose Maria Cordova Intl
6h 12m
SCL1:13 amSantiago Arturo Merino Benitez
Feb 24
SCL2:13 amSantiago Arturo Merino Benitez
6h 15m
MDE6:28 amMedellín Jose Maria Cordova Intl
$387

Copa Airlines flights from Medellín Jose Maria Cordova Intl Airport to Santiago

Our best Copa Airlines deals on Medellín Jose Maria Cordova Intl Airport to Santiago flight tickets
Copa Airlines
Nov 13
MDE12:40 pmMedellín Jose Maria Cordova Intl
8h 56m
1 stop
SCL11:36 pmSantiago Arturo Merino Benitez
Nov 26
SCL3:48 amSantiago Arturo Merino Benitez
9h 07m
1 stop
MDE10:55 amMedellín Jose Maria Cordova Intl
$474
Copa Airlines
Nov 5
MDE6:25 amMedellín Jose Maria Cordova Intl
15h 11m
1 stop
SCL11:36 pmSantiago Arturo Merino Benitez
Nov 12
SCL5:07 amSantiago Arturo Merino Benitez
11h 38m
1 stop
MDE2:45 pmMedellín Jose Maria Cordova Intl
$491
Copa Airlines
Nov 3
MDE12:40 pmMedellín Jose Maria Cordova Intl
12h 58m
1 stop
SCL3:38 amSantiago Arturo Merino Benitez
Nov 13
SCL1:02 amSantiago Arturo Merino Benitez
9h 13m
1 stop
MDE8:15 amMedellín Jose Maria Cordova Intl
$502

momondo Fare Finder

 
Use the filters below to find and compare flights from Medellín Jose Maria Cordova Intl Airport to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MedellínSantiago

MDE Medellín Jose Maria Cordova Intl - SCL Santiago Arturo Merino Benitez

MDESCL

Medellín Jose Maria Cordova Intl

Sat 12/26

8:31 am-5:05 am

1 stop18h 34m

Santiago Arturo Merino Benitez

Thu 2/25

12:32 pm-4:46 pm

1 stop30h 14m

$369

MedellínSantiago

MDE Medellín Jose Maria Cordova Intl - SCL Santiago Arturo Merino Benitez

MDESCL

Medellín Jose Maria Cordova Intl

Tue 12/8

8:31 am-10:55 am

1 stop24h 24m

Santiago Arturo Merino Benitez

Sun 3/7

12:32 pm-4:46 pm

1 stop30h 14m

$369

MedellínSantiago

MDE Medellín Jose Maria Cordova Intl - SCL Santiago Arturo Merino Benitez

MDESCL

Medellín Jose Maria Cordova Intl

Sat 12/12

8:31 am-5:05 am

1 stop18h 34m

Santiago Arturo Merino Benitez

Thu 3/4

6:07 am-4:46 pm

1 stop12h 39m

$369

MedellínSantiago

MDE Medellín Jose Maria Cordova Intl - SCL Santiago Arturo Merino Benitez

MDESCL

Medellín Jose Maria Cordova Intl

Sat 1/30

5:01 pm-1:13 am

Nonstop6h 12m

Santiago Arturo Merino Benitez

Fri 3/12

4:36 pm-9:20 pm

1 stop30h 44m

$425

MedellínSantiago

MDE Medellín Jose Maria Cordova Intl - SCL Santiago Arturo Merino Benitez

MDESCL

Medellín Jose Maria Cordova Intl

Fri 2/5

5:00 am-3:10 pm

2 stops32h 10m

Santiago Arturo Merino Benitez

Wed 3/17

2:13 am-6:28 am

Nonstop6h 15m

$425

MedellínSantiago

MDE Medellín Jose Maria Cordova Intl - SCL Santiago Arturo Merino Benitez

MDESCL

Medellín Jose Maria Cordova Intl

Wed 2/3

7:30 am-11:36 pm

2 stops14h 06m

Santiago Arturo Merino Benitez

Sun 3/14

2:13 am-6:28 am

Nonstop6h 15m

$425
Quickest round-trip

MedellínSantiago

MDE Medellín Jose Maria Cordova Intl - SCL Santiago Arturo Merino Benitez

MDESCL

Medellín Jose Maria Cordova Intl

Wed 4/7

6:10 pm-4:20 am

1 stop9h 10m

Santiago Arturo Merino Benitez

Thu 4/15

8:40 am-4:25 pm

1 stop8h 45m

$472

MedellínSantiago

MDE Medellín Jose Maria Cordova Intl - SCL Santiago Arturo Merino Benitez

MDESCL

Medellín Jose Maria Cordova Intl

Wed 4/7

10:55 am-1:50 am

2 stops13h 55m

Santiago Arturo Merino Benitez

Thu 4/15

6:40 am-4:25 pm

1 stop10h 45m

$478

MedellínSantiago

MDE Medellín Jose Maria Cordova Intl - SCL Santiago Arturo Merino Benitez

MDESCL

Medellín Jose Maria Cordova Intl

Fri 1/29

4:30 am-3:10 pm

1 stop8h 40m

Santiago Arturo Merino Benitez

Thu 3/18

7:30 am-4:50 pm

1 stop11h 20m

$652

MedellínSantiago

MDE Medellín Jose Maria Cordova Intl - SCL Santiago Arturo Merino Benitez

MDESCL

Medellín Jose Maria Cordova Intl

Tue 11/24

4:10 pm-5:45 am

1 stop11h 35m

Santiago Arturo Merino Benitez

Wed 12/2

4:15 pm-11:20 pm

1 stop9h 05m

$680

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Medellín Jose Maria Cordova Intl Airport to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Medellín Jose Maria Cordova Intl Airport and Santiago?

Prices are currently typical for flights on this route.

Typical prices usually range from $337 to $445.
The lowest price recently found on this route was $369.

What is the cheapest month to fly to Santiago?

In general, April is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $377. If you don’t want to visit Santiago in April, then you should wait until November to fly from Medellín Jose Maria Cordova Intl Airport, when ticket prices are also cheap, with an average price of $389.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $360. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Thursday is $551.

What is the cheapest Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez flight route?

Fly from Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez for the best Medellín Jose Maria Cordova Intl - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

You are more likely to see cheaper flights to Santiago from Medellín Jose Maria Cordova Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $414 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Medellín Jose Maria Cordova Intl Airport for as low as $365 on momondo.

What cabin class options are available on Medellín Jose Maria Cordova Intl Airport to Santiago flights?

There is only 1 cabin class available to choose from on Medellín Jose Maria Cordova Intl Airport to Santiago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Medellín Jose Maria Cordova Intl Airport to Santiago flights?

You could potentially save up to 33% on your flight if you consider stops on a Medellín Jose Maria Cordova Intl Airport to Santiago flight.

How have Medellín Jose Maria Cordova Intl Airport to Santiago flight prices changed over time?

As of October 2026, prices for Medellín Jose Maria Cordova Intl Airport to Santiago flights are approximately 32% more expensive when compared to flights at the same time last year.

When to book flights from Medellín Jose Maria Cordova Intl Airport to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Medellín Jose Maria Cordova Intl Airport to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Medellín Jose Maria Cordova Intl Airport to Santiago (MDE to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medellín Jose Maria Cordova Intl Airport to Santiago

Best Price Found

$221

Fastest flight time

6h 12m

Direct flights

Every day

Airports in Santiago

1 airport
The best one-way flight to Santiago from Medellín Jose Maria Cordova Intl Airport in the past 72 hours is $221. The best round-trip flight deal from Medellín Jose Maria Cordova Intl Airport to Santiago found on momondo in the last 72 hours is $369.
The fastest flight from Medellín Jose Maria Cordova Intl Airport to Santiago takes 6h 12m
Direct flights go from Medellín Jose Maria Cordova Intl Airport to Santiago every day.
There is 1 airport in Santiago. From Medellín Jose Maria Cordova Intl Airport there are direct flights to Santiago Arturo Merino Benitez (SCL).

Frequently asked questions about flying from Medellín Jose Maria Cordova Intl Airport to Santiago

  • How far is Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez by plane?

    Medellín Jose Maria Cordova Intl and Santiago Arturo Merino Benitez are 2752.8 mi apart from one another. Typically, this will take 6h 12m by plane in normal conditions.

  • When did momondo last update prices for flights from Medellín Jose Maria Cordova Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Medellín Jose Maria Cordova Intl Airport to Santiago Arturo Merino Benitez Airport are updated daily.

  • How many operators does momondo search for flights from Medellín Jose Maria Cordova Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Medellín Jose Maria Cordova Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Medellín Jose Maria Cordova Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Medellín Jose Maria Cordova Intl Airport to Santiago?

  • What is the most popular airline from Medellín Jose Maria Cordova Intl Airport to Santiago?

Best airlines flying from Medellín Jose Maria Cordova Intl Airport to Santiago

Compare and see reviews for airlines that fly from Medellín Jose Maria Cordova Intl Airport to Santiago with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $303Free CancellationRating
7.4
1,970 reviews
Search LATAM Airlines flights
AviancaPriceFrom $310Free CancellationRating
6.5
2,549 reviews
Search Avianca flights
JetSMARTPriceFrom $311Free CancellationRating
6.9
350 reviews
Search JetSMART flights
  • JetSMART Flights From Medellín Jose Maria Cordova Intl Airport to Santiago

    JetSMART flies from Medellín Jose Maria Cordova Intl Airport to Santiago around 1 time per week, with 350 momondo users rating the airline 6.9/10. The cheapest JetSMART deal from Medellín Jose Maria Cordova Intl Airport to Santiago in the last 72 hours was $311 (round-trip), much lower than the average airfare cost of $393 for JetSMART flights on this route.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
San Fernando
Valle Nevado
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Medellín to Santiago?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Medellín to Santiago. momondo saves you time and could save you money on your trip.

Can I find flights from Medellín to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Medellín to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from Medellín to Santiago?

Once all potential Medellín to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Medellín to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Medellín to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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