Cheap flights from Columbus Airport to Santiago from $314

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbus Airport to Santiago departing on 4/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
7:00 am - 6:25 am
CMH
-
SCL
23h 25m
1 stop
LATAM Airlines Logo
10:55 pm - 5:32 pm
SCL
-
CMH
18h 37m
1 stop
$831LATAM Airlines
Wed, Aug 19 - Mon, Aug 31
LATAM Airlines Logo
5:45 pm - 1:25 pm
CMH
-
SCL
19h 40m
3 stops
LATAM Airlines Logo
10:55 pm - 5:32 pm
SCL
-
CMH
18h 37m
1 stop
$855LATAM Airlines
Wed, Aug 19 - Mon, Aug 31
LATAM Airlines Logo
12:05 pm - 6:25 am
CMH
-
SCL
18h 20m
1 stop
LATAM Airlines Logo
12:40 am - 6:49 pm
SCL
-
CMH
18h 09m
2 stops
$874LATAM Airlines
Wed, Aug 19 - Sun, Aug 30
LATAM Airlines Logo
5:45 pm - 1:25 pm
CMH
-
SCL
19h 40m
3 stops
LATAM Airlines Logo
12:40 am - 6:49 pm
SCL
-
CMH
18h 09m
2 stops
$893LATAM Airlines
Wed, Aug 19 - Sun, Aug 30
LATAM Airlines Logo
12:05 pm - 6:25 am
CMH
-
SCL
18h 20m
1 stop
LATAM Airlines Logo
4:10 am - 11:59 pm
SCL
-
CMH
19h 49m
2 stops
$917LATAM Airlines
Thu, Aug 20 - Sat, Sep 5
LATAM Airlines Logo
12:05 pm - 6:55 am
CMH
-
SCL
18h 50m
2 stops
LATAM Airlines Logo
4:10 am - 11:59 pm
SCL
-
CMH
19h 49m
2 stops
$941LATAM Airlines
Thu, Aug 20 - Sat, Sep 5
LATAM Airlines Logo
12:05 pm - 6:25 am
CMH
-
SCL
18h 20m
1 stop
LATAM Airlines Logo
10:55 pm - 5:32 pm
SCL
-
CMH
18h 37m
1 stop
$948LATAM Airlines
Thu, Aug 20 - Sat, Sep 5
LATAM Airlines Logo
12:44 pm - 6:25 am
CMH
-
SCL
17h 41m
1 stop
LATAM Airlines Logo
10:55 pm - 5:49 pm
SCL
-
CMH
18h 54m
1 stop
$1,004LATAM Airlines
Mon, Jun 1 - Mon, Jun 22
LATAM Airlines Logo
5:45 pm - 1:25 pm
CMH
-
SCL
19h 40m
3 stops
LATAM Airlines Logo
8:30 am - 10:30 am
SCL
-
CMH
26h 00m
3 stops
$1,011LATAM Airlines
Thu, Aug 20 - Sat, Sep 5
LATAM Airlines Logo
7:05 am - 6:50 am
CMH
-
SCL
23h 45m
1 stop
LATAM Airlines Logo
10:55 pm - 5:49 pm
SCL
-
CMH
18h 54m
1 stop
$1,031LATAM Airlines
Sun, Jun 14 - Sat, Jun 20

LATAM Airlines flights from Columbus Airport to Santiago

Our best LATAM Airlines deals on Columbus Airport to Santiago flight tickets
LATAM Airlines
Aug 19
CMH7:00 amColumbus
23h 25m
1 stop
SCL6:25 amSantiago Arturo Merino Benitez
Aug 31
SCL10:55 pmSantiago Arturo Merino Benitez
18h 37m
1 stop
CMH5:32 pmColumbus
$831
LATAM Airlines
Aug 19
CMH5:45 pmColumbus
19h 40m
3 stops
SCL1:25 pmSantiago Arturo Merino Benitez
Aug 31
SCL10:55 pmSantiago Arturo Merino Benitez
18h 37m
1 stop
CMH5:32 pmColumbus
$855
LATAM Airlines
Aug 19
CMH12:05 pmColumbus
18h 20m
1 stop
SCL6:25 amSantiago Arturo Merino Benitez
Aug 30
SCL12:40 amSantiago Arturo Merino Benitez
18h 09m
2 stops
CMH6:49 pmColumbus
$874

American Airlines flights from Columbus Airport to Santiago

Our best American Airlines deals on Columbus Airport to Santiago flight tickets
American Airlines
Jun 1
CMH11:10 amColumbus
19h 55m
2 stops
SCL7:05 amSantiago Arturo Merino Benitez
Jun 22
SCL9:00 pmSantiago Arturo Merino Benitez
18h 30m
2 stops
CMH3:30 pmColumbus
$1,086
American Airlines
May 14
CMH11:42 amColumbus
19h 23m
2 stops
SCL7:05 amSantiago Arturo Merino Benitez
May 21
SCL9:00 pmSantiago Arturo Merino Benitez
16h 29m
1 stop
CMH1:29 pmColumbus
$1,158

momondo Fare Finder

 
Customize your flight search to find flights from Columbus Airport to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 2, 2026.
Use the filters below to find and compare flights from Columbus Airport to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Wed 8/19

7:00 am-6:25 am

1 stop23h 25m

Santiago Arturo Merino Benitez

Mon 8/31

10:55 pm-5:32 pm

1 stop18h 37m

$831

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Wed 8/19

5:45 pm-1:25 pm

3 stops19h 40m

Santiago Arturo Merino Benitez

Mon 8/31

10:55 pm-5:32 pm

1 stop18h 37m

$855
Quickest round-trip

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Wed 8/19

12:05 pm-6:25 am

1 stop18h 20m

Santiago Arturo Merino Benitez

Sun 8/30

12:40 am-6:49 pm

2 stops18h 09m

$874

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Wed 8/19

5:45 pm-1:25 pm

3 stops19h 40m

Santiago Arturo Merino Benitez

Sun 8/30

12:40 am-6:49 pm

2 stops18h 09m

$893

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Thu 8/20

12:05 pm-6:25 am

1 stop18h 20m

Santiago Arturo Merino Benitez

Sat 9/5

4:10 am-11:59 pm

2 stops19h 49m

$917

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Thu 8/20

12:05 pm-6:55 am

2 stops18h 50m

Santiago Arturo Merino Benitez

Sat 9/5

4:10 am-11:59 pm

2 stops19h 49m

$941

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Thu 8/20

12:05 pm-6:25 am

1 stop18h 20m

Santiago Arturo Merino Benitez

Sat 9/5

10:55 pm-5:32 pm

1 stop18h 37m

$948

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Mon 6/1

12:44 pm-6:25 am

1 stop17h 41m

Santiago Arturo Merino Benitez

Mon 6/22

10:55 pm-5:49 pm

1 stop18h 54m

$1,004

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Thu 8/20

5:45 pm-1:25 pm

3 stops19h 40m

Santiago Arturo Merino Benitez

Sat 9/5

8:30 am-10:30 am

3 stops26h 00m

$1,011

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Sun 6/14

7:05 am-6:50 am

1 stop23h 45m

Santiago Arturo Merino Benitez

Sat 6/20

10:55 pm-5:49 pm

1 stop18h 54m

$1,031

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Columbus Airport to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Columbus Airport and Santiago?

When to book flights from Columbus Airport to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Columbus Airport to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbus Airport to Santiago (CMH to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus Airport to Santiago

Fastest flight time

15h 25m

Direct flights

None
The fastest flight from Columbus Airport to Santiago takes 15h 25m
There are no direct flights from Columbus Airport to Santiago. There are no popular flight routes from Columbus Airport to Santiago.

Frequently asked questions about flying from Columbus Airport to Santiago

  • How far is Columbus to Santiago Arturo Merino Benitez by plane?

    Columbus and Santiago Arturo Merino Benitez are 5130.9 mi apart from one another. In terms of flight time, this usually takes a little over 15h 25m.

  • When did momondo last update prices for flights from Columbus Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Columbus Airport to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Columbus Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Columbus Airport to Santiago Arturo Merino Benitez Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbus Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Columbus Airport to Santiago?

Best airlines flying from Columbus Airport to Santiago

Compare and see reviews for airlines that fly from Columbus Airport to Santiago with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $764Free CancellationRating
7.9
8,371 reviews
Search Delta flights
LATAM AirlinesPriceFrom $787Free CancellationRating
7.4
1,907 reviews
Search LATAM Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Columbus to Santiago for you.

Can I find flights from Columbus to Santiago with flexible booking policies on momondo?

Flights from Columbus to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Columbus to Santiago?

Once all potential Columbus to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Columbus to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from Columbus. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Sat 5/2
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