Cheap flights from Columbus Airport to Santiago from $375

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbus Airport to Santiago departing on 3/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
12:36 pm - 6:50 am
CMH
-
SCL
18h 14m
1 stop
LATAM Airlines Logo
10:55 pm - 5:39 pm
SCL
-
CMH
18h 44m
1 stop
$804LATAM Airlines
Wed, May 13 - Wed, May 20
Air Canada Logo
9:30 am - 11:15 am
CMH
-
SCL
24h 45m
1 stop
Air Canada Logo
7:55 pm - 8:56 pm
SCL
-
CMH
26h 01m
1 stop
$814Air Canada
Wed, Mar 11 - Wed, Mar 18
Air Canada Logo
9:30 am - 11:15 am
CMH
-
SCL
24h 45m
1 stop
Air Canada Logo
7:55 pm - 8:56 pm
SCL
-
CMH
26h 01m
1 stop
$819Air Canada
Tue, Mar 10 - Wed, Mar 18
LATAM Airlines Logo
12:36 pm - 6:50 am
CMH
-
SCL
18h 14m
1 stop
LATAM Airlines Logo
5:40 am - 12:15 am
SCL
-
CMH
18h 35m
2 stops
$821LATAM Airlines
Wed, May 13 - Wed, May 20
LATAM Airlines Logo
6:24 pm - 8:15 am
CMH
-
SCL
12h 51m
1 stop
LATAM Airlines Logo
10:55 pm - 5:26 pm
SCL
-
CMH
18h 31m
1 stop
$839LATAM Airlines
Wed, Apr 1 - Wed, Apr 8
LATAM Airlines Logo
6:24 pm - 2:05 pm
CMH
-
SCL
18h 41m
2 stops
LATAM Airlines Logo
5:15 am - 12:24 am
SCL
-
CMH
20h 09m
2 stops
$840LATAM Airlines
Wed, Mar 18 - Wed, Mar 25
LATAM Airlines Logo
2:59 pm - 6:55 am
CMH
-
SCL
15h 56m
2 stops
LATAM Airlines Logo
4:10 am - 12:15 am
SCL
-
CMH
20h 05m
2 stops
$844LATAM Airlines
Wed, May 13 - Wed, May 20
LATAM Airlines Logo
1:00 pm - 7:40 am
CMH
-
SCL
17h 40m
1 stop
LATAM Airlines Logo
8:50 am - 12:24 am
SCL
-
CMH
16h 34m
2 stops
$858LATAM Airlines
Tue, Mar 17 - Thu, Mar 26
LATAM Airlines Logo
1:00 pm - 1:40 pm
CMH
-
SCL
23h 40m
3 stops
LATAM Airlines Logo
7:15 am - 12:24 am
SCL
-
CMH
17h 09m
2 stops
$863LATAM Airlines
Mon, Mar 30 - Mon, Apr 6
Delta Logo
6:00 pm - 5:55 am
CMH
-
SCL
34h 55m
1 stop
Delta Logo
8:50 am - 12:24 am
SCL
-
CMH
16h 34m
2 stops
$866Delta
Sun, Mar 15 - Thu, Mar 26

LATAM Airlines flights from Columbus Airport to Santiago

Our best LATAM Airlines deals on Columbus Airport to Santiago flight tickets
LATAM Airlines
May 13
CMH12:36 pmColumbus
18h 14m
1 stop
SCL6:50 amSantiago Arturo Merino Benitez
May 20
SCL10:55 pmSantiago Arturo Merino Benitez
18h 44m
1 stop
CMH5:39 pmColumbus
$804
LATAM Airlines
May 13
CMH12:36 pmColumbus
18h 14m
1 stop
SCL6:50 amSantiago Arturo Merino Benitez
May 20
SCL5:40 amSantiago Arturo Merino Benitez
18h 35m
2 stops
CMH12:15 amColumbus
$821
LATAM Airlines
Apr 1
CMH6:24 pmColumbus
12h 51m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
Apr 8
SCL10:55 pmSantiago Arturo Merino Benitez
18h 31m
1 stop
CMH5:26 pmColumbus
$839

Air Canada flights from Columbus Airport to Santiago

Our best Air Canada deals on Columbus Airport to Santiago flight tickets
Air Canada
Mar 11
CMH9:30 amColumbus
24h 45m
1 stop
SCL11:15 amSantiago Arturo Merino Benitez
Mar 18
SCL7:55 pmSantiago Arturo Merino Benitez
26h 01m
1 stop
CMH8:56 pmColumbus
$814
Air Canada
Mar 10
CMH9:30 amColumbus
24h 45m
1 stop
SCL11:15 amSantiago Arturo Merino Benitez
Mar 18
SCL7:55 pmSantiago Arturo Merino Benitez
26h 01m
1 stop
CMH8:56 pmColumbus
$819

momondo Fare Finder

 
Customize your flight search to find flights from Columbus Airport to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 15, 2026.
Use the filters below to find and compare flights from Columbus Airport to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Wed 5/13

12:36 pm-6:50 am

1 stop18h 14m

Santiago Arturo Merino Benitez

Wed 5/20

10:55 pm-5:39 pm

1 stop18h 44m

$804

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Wed 3/11

9:30 am-11:15 am

1 stop24h 45m

Santiago Arturo Merino Benitez

Wed 3/18

7:55 pm-8:56 pm

1 stop26h 01m

$814

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Tue 3/10

9:30 am-11:15 am

1 stop24h 45m

Santiago Arturo Merino Benitez

Wed 3/18

7:55 pm-8:56 pm

1 stop26h 01m

$819

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Wed 5/13

12:36 pm-6:50 am

1 stop18h 14m

Santiago Arturo Merino Benitez

Wed 5/20

5:40 am-12:15 am

2 stops18h 35m

$821

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Wed 4/1

6:24 pm-8:15 am

1 stop12h 51m

Santiago Arturo Merino Benitez

Wed 4/8

10:55 pm-5:26 pm

1 stop18h 31m

$839

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Wed 3/18

6:24 pm-2:05 pm

2 stops18h 41m

Santiago Arturo Merino Benitez

Wed 3/25

5:15 am-12:24 am

2 stops20h 09m

$840

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Wed 5/13

2:59 pm-6:55 am

2 stops15h 56m

Santiago Arturo Merino Benitez

Wed 5/20

4:10 am-12:15 am

2 stops20h 05m

$844

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Tue 3/17

1:00 pm-7:40 am

1 stop17h 40m

Santiago Arturo Merino Benitez

Thu 3/26

8:50 am-12:24 am

2 stops16h 34m

$858

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Mon 3/30

1:00 pm-1:40 pm

3 stops23h 40m

Santiago Arturo Merino Benitez

Mon 4/6

7:15 am-12:24 am

2 stops17h 09m

$863

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Sun 3/15

6:00 pm-5:55 am

1 stop34h 55m

Santiago Arturo Merino Benitez

Thu 3/26

8:50 am-12:24 am

2 stops16h 34m

$866

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Columbus Airport to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Columbus Airport and Santiago?

When to book flights from Columbus Airport to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Columbus Airport to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbus Airport to Santiago (CMH to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus Airport to Santiago

Fastest flight time

14h 26m

Direct flights

None
The fastest flight from Columbus Airport to Santiago takes 14h 26m
There are no direct flights from Columbus Airport to Santiago. There are no popular flight routes from Columbus Airport to Santiago.
  • How far is Columbus to Santiago Arturo Merino Benitez by plane?

    Columbus and Santiago Arturo Merino Benitez are 5130.9 mi apart from one another. In terms of flight time, this usually takes a little over 14h 26m.

  • When did momondo last update prices for flights from Columbus Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Columbus Airport to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Columbus Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Columbus Airport to Santiago Arturo Merino Benitez Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbus Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Columbus Airport to Santiago?

Best airlines flying from Columbus Airport to Santiago

Compare and see reviews for airlines that fly from Columbus Airport to Santiago with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $748Free CancellationRating
7.5
1,919 reviews
Search LATAM Airlines flights
DeltaPriceFrom $768Free CancellationRating
7.9
8,204 reviews
Search Delta flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

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Why should I use momondo to find a flight deal from Columbus to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Columbus to Santiago for you.

Can I find flights from Columbus to Santiago with flexible booking policies on momondo?

Flights from Columbus to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Columbus to Santiago?

Once all potential Columbus to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Columbus to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from Columbus. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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1 adult
Tue 3/17
Tue 3/24

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