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Cheap flights from Columbus Airport to Santiago from $420

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbus Airport to Santiago departing on 1/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbus Airport to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
12:57 pm - 6:55 amCMH-SCL
15h 58m1 stop
LATAM Airlines Logo
11:30 pm - 12:10 pmSCL-CMH
14h 40m1 stop
$699LATAM Airlines
Find Deal
mar., ene. 20 - mar., feb. 3
LATAM Airlines Logo
12:57 pm - 6:55 amCMH-SCL
15h 58m1 stop
LATAM Airlines Logo
11:30 pm - 12:01 pmSCL-CMH
14h 31m1 stop
$721LATAM Airlines
Find Deal
lun., feb. 2 - mar., feb. 24
LATAM Airlines Logo
12:57 pm - 6:55 amCMH-SCL
15h 58m1 stop
LATAM Airlines Logo
6:30 pm - 11:46 amSCL-CMH
19h 16m2 stops
$732LATAM Airlines
Find Deal
lun., feb. 2 - mar., feb. 24
Multiple Airlines Logo
10:40 am - 10:39 amCMH-SCL
21h 59m2 stops
Multiple Airlines Logo
11:24 am - 9:40 amSCL-CMH
24h 16m2 stops
$734Multiple Airlines
Find Deal
lun., feb. 2 - mar., feb. 24
LATAM Airlines Logo
5:00 pm - 2:30 pmCMH-SCL
19h 30m3 stops
LATAM Airlines Logo
11:30 pm - 12:10 pmSCL-CMH
14h 40m1 stop
$737LATAM Airlines
Find Deal
mar., ene. 20 - mar., feb. 3
Multiple Airlines Logo
5:33 am - 10:39 amCMH-SCL
27h 06m3 stops
Multiple Airlines Logo
11:24 am - 9:40 amSCL-CMH
24h 16m2 stops
$742Multiple Airlines
Find Deal
lun., feb. 2 - mar., feb. 24
LATAM Airlines Logo
11:02 am - 11:05 amCMH-SCL
22h 03m3 stops
LATAM Airlines Logo
12:20 am - 8:24 pmSCL-CMH
22h 04m2 stops
$764LATAM Airlines
Find Deal
lun., feb. 2 - lun., feb. 23
Multiple Airlines Logo
10:31 am - 10:39 amCMH-SCL
22h 08m3 stops
Multiple Airlines Logo
4:25 pm - 11:58 pmSCL-CMH
33h 33m3 stops
$765Multiple Airlines
Find Deal
sáb., ene. 17 - mar., ene. 27
LATAM Airlines Logo
12:57 pm - 6:55 amCMH-SCL
15h 58m1 stop
LATAM Airlines Logo
6:30 pm - 11:44 amSCL-CMH
19h 14m2 stops
$768LATAM Airlines
Find Deal
sáb., ene. 17 - mar., ene. 27
LATAM Airlines Logo
5:00 pm - 2:30 pmCMH-SCL
19h 30m3 stops
LATAM Airlines Logo
8:50 pm - 12:10 pmSCL-CMH
17h 20m2 stops
$769LATAM Airlines
Find Deal
mar., ene. 20 - mar., feb. 3

Delta flights from Columbus Airport to Santiago

Our best Delta deals on Columbus Airport to Santiago flight tickets
Delta
Dec 6
CMH12:26 pmColumbus
16h 09m
2 stops
SCL6:35 amSantiago Arturo Merino Benitez
Dec 10
SCL11:10 pmSantiago Arturo Merino Benitez
18h 33m
1 stop
CMH3:43 pmColumbus
$804
Find similar
Delta
Mar 17
CMH1:00 pmColumbus
15h 50m
2 stops
SCL5:50 amSantiago Arturo Merino Benitez
Mar 19
SCL10:30 pmSantiago Arturo Merino Benitez
14h 14m
1 stop
CMH11:44 amColumbus
$1,094
Find similar

Copa Airlines flights from Columbus Airport to Santiago

Our best Copa Airlines deals on Columbus Airport to Santiago flight tickets
Copa Airlines
May 13
CMH9:10 amColumbus
19h 50m
2 stops
SCL5:00 amSantiago Arturo Merino Benitez
May 19
SCL12:16 amSantiago Arturo Merino Benitez
21h 55m
2 stops
CMH10:11 pmColumbus
$953
Find similar
Copa Airlines
May 13
CMH9:10 amColumbus
19h 50m
2 stops
SCL5:00 amSantiago Arturo Merino Benitez
May 19
SCL12:46 amSantiago Arturo Merino Benitez
19h 59m
2 stops
CMH8:45 pmColumbus
$1,087
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Columbus Airport to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated noviembre 19, 2025.
Use the filters below to find and compare flights from Columbus Airport to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

mar. 1/20

12:57 pm-6:55 am

1 stop15h 58m

Santiago Arturo Merino Benitez

mar. 2/3

11:30 pm-12:10 pm

1 stop14h 40m

$699

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

lun. 2/2

12:57 pm-6:55 am

1 stop15h 58m

Santiago Arturo Merino Benitez

mar. 2/24

11:30 pm-12:01 pm

1 stop14h 31m

$721

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

lun. 2/2

12:57 pm-6:55 am

1 stop15h 58m

Santiago Arturo Merino Benitez

mar. 2/24

6:30 pm-11:46 am

2 stops19h 16m

$732

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

lun. 2/2

10:40 am-10:39 am

2 stops21h 59m

Santiago Arturo Merino Benitez

mar. 2/24

11:24 am-9:40 am

2 stops24h 16m

$734

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

mar. 1/20

5:00 pm-2:30 pm

3 stops19h 30m

Santiago Arturo Merino Benitez

mar. 2/3

11:30 pm-12:10 pm

1 stop14h 40m

$737

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

lun. 2/2

5:33 am-10:39 am

3 stops27h 06m

Santiago Arturo Merino Benitez

mar. 2/24

11:24 am-9:40 am

2 stops24h 16m

$742

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

lun. 2/2

11:02 am-11:05 am

3 stops22h 03m

Santiago Arturo Merino Benitez

lun. 2/23

12:20 am-8:24 pm

2 stops22h 04m

$764

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

sáb. 1/17

10:31 am-10:39 am

3 stops22h 08m

Santiago Arturo Merino Benitez

mar. 1/27

4:25 pm-11:58 pm

3 stops33h 33m

$765

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

sáb. 1/17

12:57 pm-6:55 am

1 stop15h 58m

Santiago Arturo Merino Benitez

mar. 1/27

6:30 pm-11:44 am

2 stops19h 14m

$768

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

mar. 1/20

5:00 pm-2:30 pm

3 stops19h 30m

Santiago Arturo Merino Benitez

mar. 2/3

8:50 pm-12:10 pm

2 stops17h 20m

$769

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Columbus Airport to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, April is the cheapest month to fly from Columbus Airport to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $848. If you don’t want to visit Santiago in April, then you should wait until November to fly from Columbus Airport, when ticket prices are also cheap, with an average price of $896.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Tuesday when prices can be found for as low as $788. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Sunday is $1,302.

What is the cheapest time of day to depart on your flight to Santiago?

In the afternoon is the cheapest time of day to fly from Columbus Airport to Santiago when you can find flight prices for as low as $952. Flying to Santiago in the afternoon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,141 per ticket.

When to book flights from Columbus Airport to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Columbus Airport to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbus Airport to Santiago (CMH to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus Airport to Santiago

Direct flights

None
There are no direct flights from Columbus Airport to Santiago. There are no popular flight routes from Columbus Airport to Santiago.
Search flight deals

  • How far is Columbus to Santiago Arturo Merino Benitez by plane?

    Columbus and Santiago Arturo Merino Benitez are 5130.9 mi apart from one another. In terms of flight time, this usually takes a little over 12h 40m.

  • When did momondo last update prices for flights from Columbus Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Columbus Airport to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Columbus Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Columbus Airport to Santiago Arturo Merino Benitez Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbus Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Columbus Airport to Santiago?

Best airlines flying from Columbus Airport to Santiago

Compare and see reviews for airlines that fly from Columbus Airport to Santiago with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $732Free CancellationRating
7.5
1,879 reviews
Search LATAM Airlines flights
DeltaPriceFrom $732Free CancellationRating
7.9
8,002 reviews
Search Delta flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Columbus to Santiago for you.

Can I find flights from Columbus to Santiago with flexible booking policies on momondo?

Flights from Columbus to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Columbus to Santiago?

Once all potential Columbus to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Columbus to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from Columbus. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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