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Cheap flights from Columbus Airport to Panama City from $278

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbus Airport to Panama City departing on 3/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbus Airport to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
9:49 am - 7:31 pm
CMH
-
PTY
10h 42m
1 stop
United Airlines Logo
10:55 pm - 10:51 am
PTY
-
CMH
10h 56m
1 stop
$465United Airlines
Wed, Apr 15 - Mon, Apr 20
United Airlines Logo
9:00 am - 6:37 pm
CMH
-
PTY
10h 37m
2 stops
United Airlines Logo
3:30 pm - 9:59 am
PTY
-
CMH
17h 29m
2 stops
$469United Airlines
Thu, Aug 20 - Wed, Aug 26
United Airlines Logo
5:01 pm - 4:12 pm
CMH
-
PTY
24h 11m
1 stop
United Airlines Logo
10:55 pm - 1:17 pm
PTY
-
CMH
13h 22m
2 stops
$479United Airlines
Mon, Jun 1 - Tue, Jun 30
United Airlines Logo
11:38 am - 7:31 pm
CMH
-
PTY
8h 53m
1 stop
United Airlines Logo
9:45 am - 9:58 pm
PTY
-
CMH
11h 13m
1 stop
$482United Airlines
Fri, May 8 - Mon, May 11
United Airlines Logo
6:30 am - 6:37 pm
CMH
-
PTY
13h 07m
1 stop
United Airlines Logo
10:00 am - 11:59 pm
PTY
-
CMH
12h 59m
1 stop
$483United Airlines
Wed, Jul 8 - Wed, Jul 15
Copa Airlines Logo
5:38 pm - 4:04 am
CMH
-
PTY
11h 26m
1 stop
Copa Airlines Logo
10:00 am - 10:03 pm
PTY
-
CMH
11h 03m
1 stop
$484Copa Airlines
Tue, Apr 21 - Sun, Apr 26
United Airlines Logo
11:38 am - 7:31 pm
CMH
-
PTY
8h 53m
1 stop
United Airlines Logo
10:00 am - 10:03 pm
PTY
-
CMH
11h 03m
1 stop
$485United Airlines
Wed, Apr 15 - Mon, Apr 20
United Airlines Logo
9:01 am - 6:37 pm
CMH
-
PTY
10h 36m
2 stops
United Airlines Logo
10:55 pm - 3:20 pm
PTY
-
CMH
15h 25m
2 stops
$486United Airlines
Tue, Apr 28 - Fri, May 1
Copa Airlines Logo
5:30 am - 4:12 pm
CMH
-
PTY
11h 42m
2 stops
Copa Airlines Logo
7:55 am - 10:03 pm
PTY
-
CMH
13h 08m
1 stop
$488Copa Airlines
Tue, Apr 21 - Sun, Apr 26
United Airlines Logo
11:38 am - 7:31 pm
CMH
-
PTY
8h 53m
1 stop
United Airlines Logo
3:30 pm - 1:12 pm
PTY
-
CMH
20h 42m
2 stops
$489United Airlines
Wed, Apr 15 - Mon, Apr 20

Copa Airlines flights from Columbus Airport to Panama City

Our best Copa Airlines deals on Columbus Airport to Panama City flight tickets
Copa Airlines
Apr 21
CMH5:38 pmColumbus
11h 26m
1 stop
PTY4:04 amPanama City Tocumen Intl
Apr 26
PTY10:00 amPanama City Tocumen Intl
11h 03m
1 stop
CMH10:03 pmColumbus
$484
Copa Airlines
Apr 21
CMH5:30 amColumbus
11h 42m
2 stops
PTY4:12 pmPanama City Tocumen Intl
Apr 26
PTY7:55 amPanama City Tocumen Intl
13h 08m
1 stop
CMH10:03 pmColumbus
$488
Copa Airlines
May 23
CMH6:35 amColumbus
13h 56m
1 stop
PTY7:31 pmPanama City Tocumen Intl
May 30
PTY3:30 pmPanama City Tocumen Intl
18h 32m
1 stop
CMH11:02 amColumbus
$501

American Airlines flights from Columbus Airport to Panama City

Our best American Airlines deals on Columbus Airport to Panama City flight tickets
American Airlines
Apr 1
CMH7:00 amColumbus
9h 01m
1 stop
PTY3:01 pmPanama City Tocumen Intl
Apr 8
PTY1:49 pmPanama City Tocumen Intl
19h 53m
2 stops
CMH10:42 amColumbus
$532
American Airlines
May 2
CMH3:51 pmColumbus
21h 55m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 9
PTY1:49 pmPanama City Tocumen Intl
20h 23m
2 stops
CMH11:12 amColumbus
$575
American Airlines
Apr 29
CMH7:35 pmColumbus
18h 11m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 2
PTY1:49 pmPanama City Tocumen Intl
18h 31m
2 stops
CMH9:20 amColumbus
$596

momondo Fare Finder

 
Customize your flight search to find flights from Columbus Airport to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 2, 2026.
Use the filters below to find and compare flights from Columbus Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 4/15

9:49 am-7:31 pm

1 stop10h 42m

Panama City Tocumen Intl

Mon 4/20

10:55 pm-10:51 am

1 stop10h 56m

$465

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 8/20

9:00 am-6:37 pm

2 stops10h 37m

Panama City Tocumen Intl

Wed 8/26

3:30 pm-9:59 am

2 stops17h 29m

$469

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 6/1

5:01 pm-4:12 pm

1 stop24h 11m

Panama City Tocumen Intl

Tue 6/30

10:55 pm-1:17 pm

2 stops13h 22m

$479

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Fri 5/8

11:38 am-7:31 pm

1 stop8h 53m

Panama City Tocumen Intl

Mon 5/11

9:45 am-9:58 pm

1 stop11h 13m

$482

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 7/8

6:30 am-6:37 pm

1 stop13h 07m

Panama City Tocumen Intl

Wed 7/15

10:00 am-11:59 pm

1 stop12h 59m

$483

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 4/21

5:38 pm-4:04 am

1 stop11h 26m

Panama City Tocumen Intl

Sun 4/26

10:00 am-10:03 pm

1 stop11h 03m

$484

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 4/15

11:38 am-7:31 pm

1 stop8h 53m

Panama City Tocumen Intl

Mon 4/20

10:00 am-10:03 pm

1 stop11h 03m

$485

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 4/28

9:01 am-6:37 pm

2 stops10h 36m

Panama City Tocumen Intl

Fri 5/1

10:55 pm-3:20 pm

2 stops15h 25m

$486

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 4/21

5:30 am-4:12 pm

2 stops11h 42m

Panama City Tocumen Intl

Sun 4/26

7:55 am-10:03 pm

1 stop13h 08m

$488

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 4/15

11:38 am-7:31 pm

1 stop8h 53m

Panama City Tocumen Intl

Mon 4/20

3:30 pm-1:12 pm

2 stops20h 42m

$489

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Columbus Airport to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Columbus Airport and Panama City?

What is the cheapest month to fly to Panama City?

In general, May is the cheapest month to fly from Columbus Airport to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $478. If you’re not able to fly to Panama City in May, then October is your next best option. Flight prices from Columbus Airport to Panama City during October average around $480.

Can stopping save me money on Columbus Airport to Panama City flights?

You could potentially save up to 35% on your flight if you consider stops on a Columbus Airport to Panama City flight.

When to book flights from Columbus Airport to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Columbus Airport to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbus Airport to Panama City (CMH to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus Airport to Panama City

Fastest flight time

7h 57m

Direct flights

None
The fastest flight from Columbus Airport to Panama City takes 7h 57m
There are no direct flights from Columbus Airport to Panama City. There are no popular flight routes from Columbus Airport to Panama City.
Search flight deals

  • How far is Columbus to Panama City Tocumen Intl by plane?

    There are 2151.5 mi between Columbus and Panama City Tocumen Intl. A reasonable flight in good conditions will take 7h 57m.

  • When did momondo last update prices for flights from Columbus Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Columbus Airport to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from Columbus Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Columbus Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbus Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Columbus Airport to Panama City?

Best airlines flying from Columbus Airport to Panama City

Compare and see reviews for airlines that fly from Columbus Airport to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $263Free CancellationRating
7.9
8,242 reviews
Search Delta flights
American AirlinesPriceFrom $413Free CancellationRating
7.1
11,375 reviews
Search American Airlines flights
United AirlinesPriceFrom $413Free CancellationRating
7.4
9,377 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to Panama City?

Finding the right flight to Panama City from Columbus is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Columbus to Panama City with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama City from Columbus with this policy.

How can momondo help me find flights from Columbus to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Columbus to Panama City.

I’m not ready to book a flight from Columbus to Panama City right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Columbus to Panama City flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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