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Cheap flights from Jacksonville to Santo Domingo from $156

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Jacksonville to Santo Domingo departing on 2/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Jacksonville to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:44 pm - 9:20 am
JAX
-
SDQ
13h 36m
1 stop
American Airlines Logo
4:00 pm - 11:59 pm
SDQ
-
JAX
7h 59m
1 stop
$333American Airlines
Thu, May 7 - Thu, May 14
Delta Logo
3:06 pm - 12:32 am
JAX
-
SDQ
8h 26m
1 stop
Delta Logo
3:42 pm - 10:58 pm
SDQ
-
JAX
8h 16m
1 stop
$334Delta
Wed, Feb 25 - Wed, Mar 4
American Airlines Logo
8:10 pm - 10:00 am
JAX
-
SDQ
12h 50m
1 stop
American Airlines Logo
5:07 pm - 11:59 pm
SDQ
-
JAX
7h 52m
1 stop
$335American Airlines
Mon, Feb 23 - Thu, Feb 26
American Airlines Logo
9:53 am - 10:52 pm
JAX
-
SDQ
12h 59m
2 stops
American Airlines Logo
2:25 pm - 9:03 am
SDQ
-
JAX
18h 38m
2 stops
$337American Airlines
Thu, May 7 - Thu, May 14
Delta Logo
6:30 am - 7:14 pm
JAX
-
SDQ
11h 44m
2 stops
Delta Logo
3:42 pm - 12:01 am
SDQ
-
JAX
9h 19m
1 stop
$338Delta
Wed, Feb 25 - Wed, Mar 4
American Airlines Logo
8:10 pm - 10:00 am
JAX
-
SDQ
12h 50m
1 stop
American Airlines Logo
5:07 pm - 8:51 am
SDQ
-
JAX
16h 44m
2 stops
$339American Airlines
Mon, Feb 23 - Thu, Feb 26
American Airlines Logo
8:19 pm - 1:18 pm
JAX
-
SDQ
16h 59m
2 stops
American Airlines Logo
4:00 pm - 11:59 pm
SDQ
-
JAX
7h 59m
1 stop
$342American Airlines
Sun, May 3 - Sun, May 17
American Airlines Logo
8:07 pm - 1:00 pm
JAX
-
SDQ
16h 53m
2 stops
American Airlines Logo
10:01 am - 9:03 am
SDQ
-
JAX
23h 02m
1 stop
$344American Airlines
Mon, Mar 9 - Mon, Mar 16
American Airlines Logo
9:43 am - 3:03 pm
JAX
-
SDQ
5h 20m
1 stop
American Airlines Logo
6:00 am - 9:59 pm
SDQ
-
JAX
15h 59m
2 stops
$347American Airlines
Tue, Mar 24 - Tue, Mar 31
American Airlines Logo
7:44 pm - 9:20 am
JAX
-
SDQ
13h 36m
1 stop
American Airlines Logo
5:55 pm - 11:59 pm
SDQ
-
JAX
6h 04m
1 stop
$353American Airlines
Thu, May 7 - Thu, May 14

American Airlines flights from Jacksonville to Santo Domingo

Our best American Airlines deals on Jacksonville to Santo Domingo flight tickets
American Airlines
May 7
JAX7:44 pmJacksonville
13h 36m
1 stop
SDQ9:20 amSanto Domingo Las Americas
May 14
SDQ4:00 pmSanto Domingo Las Americas
7h 59m
1 stop
JAX11:59 pmJacksonville
$333
American Airlines
Feb 23
JAX8:10 pmJacksonville
12h 50m
1 stop
SDQ10:00 amSanto Domingo Las Americas
Feb 26
SDQ5:07 pmSanto Domingo Las Americas
7h 52m
1 stop
JAX11:59 pmJacksonville
$335
American Airlines
May 7
JAX9:53 amJacksonville
12h 59m
2 stops
SDQ10:52 pmSanto Domingo Las Americas
May 14
SDQ2:25 pmSanto Domingo Las Americas
18h 38m
2 stops
JAX9:03 amJacksonville
$337

Delta flights from Jacksonville to Santo Domingo

Our best Delta deals on Jacksonville to Santo Domingo flight tickets
Delta
Feb 25
JAX3:06 pmJacksonville
8h 26m
1 stop
SDQ12:32 amSanto Domingo Las Americas
Mar 4
SDQ3:42 pmSanto Domingo Las Americas
8h 16m
1 stop
JAX10:58 pmJacksonville
$334
Delta
Feb 19
JAX5:30 amJacksonville
7h 47m
1 stop
SDQ2:17 pmSanto Domingo Las Americas
Feb 24
SDQ3:42 pmSanto Domingo Las Americas
9h 19m
1 stop
JAX12:01 amJacksonville
$335
Delta
Feb 25
JAX6:30 amJacksonville
11h 44m
2 stops
SDQ7:14 pmSanto Domingo Las Americas
Mar 4
SDQ3:42 pmSanto Domingo Las Americas
9h 19m
1 stop
JAX12:01 amJacksonville
$338

momondo Fare Finder

 
Customize your flight search to find flights from Jacksonville to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Jacksonville to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Thu 5/7

7:44 pm-9:20 am

1 stop13h 36m

Santo Domingo Las Americas

Thu 5/14

4:00 pm-11:59 pm

1 stop7h 59m

$333

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Wed 2/25

3:06 pm-12:32 am

1 stop8h 26m

Santo Domingo Las Americas

Wed 3/4

3:42 pm-10:58 pm

1 stop8h 16m

$334

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Mon 2/23

8:10 pm-10:00 am

1 stop12h 50m

Santo Domingo Las Americas

Thu 2/26

5:07 pm-11:59 pm

1 stop7h 52m

$335

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Thu 5/7

9:53 am-10:52 pm

2 stops12h 59m

Santo Domingo Las Americas

Thu 5/14

2:25 pm-9:03 am

2 stops18h 38m

$337

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Wed 2/25

6:30 am-7:14 pm

2 stops11h 44m

Santo Domingo Las Americas

Wed 3/4

3:42 pm-12:01 am

1 stop9h 19m

$338

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Mon 2/23

8:10 pm-10:00 am

1 stop12h 50m

Santo Domingo Las Americas

Thu 2/26

5:07 pm-8:51 am

2 stops16h 44m

$339

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Sun 5/3

8:19 pm-1:18 pm

2 stops16h 59m

Santo Domingo Las Americas

Sun 5/17

4:00 pm-11:59 pm

1 stop7h 59m

$342

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Mon 3/9

8:07 pm-1:00 pm

2 stops16h 53m

Santo Domingo Las Americas

Mon 3/16

10:01 am-9:03 am

1 stop23h 02m

$344

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Tue 3/24

9:43 am-3:03 pm

1 stop5h 20m

Santo Domingo Las Americas

Tue 3/31

6:00 am-9:59 pm

2 stops15h 59m

$347

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Thu 5/7

7:44 pm-9:20 am

1 stop13h 36m

Santo Domingo Las Americas

Thu 5/14

5:55 pm-11:59 pm

1 stop6h 04m

$353

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Jacksonville to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in June, then you should wait until October to fly from Jacksonville, when ticket prices are also cheap, with an average price of $472.

How have Jacksonville to Santo Domingo flight prices changed over time?

As of February 2026, prices for Jacksonville to Santo Domingo flights are approximately 24% more expensive when compared to flights at the same time last year.

When to book flights from Jacksonville to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Jacksonville to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Jacksonville to Santo Domingo (JAX to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Jacksonville to Santo Domingo

Fastest flight time

6h 40m

Direct flights

None
The fastest flight from Jacksonville to Santo Domingo takes 6h 40m
There are no direct flights from Jacksonville to Santo Domingo. There are no popular flight routes from Jacksonville to Santo Domingo.
Search flight deals

  • How far is Jacksonville to Santo Domingo Las Americas by plane?

    Jacksonville and Santo Domingo Las Americas are 1099.6 mi apart from one another. By plane, this route typically takes 6h 40m.

  • When did momondo last update prices for flights from Jacksonville Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Jacksonville Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from Jacksonville Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Jacksonville Airport to Santo Domingo Las Americas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Jacksonville Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents you'll need for your trip to Santo Domingo Las Americas Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santo Domingo Las Americas Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Jacksonville to Santo Domingo?

Best airlines flying from Jacksonville to Santo Domingo

Compare and see reviews for airlines that fly from Jacksonville to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $204Free CancellationRating
7.9
8,180 reviews
Search Delta flights
American AirlinesPriceFrom $432Free CancellationRating
7.2
11,271 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Jacksonville to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Jacksonville to Santo Domingo for you.

Can I find flights from Jacksonville to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from Jacksonville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Jacksonville to Santo Domingo?

momondo provides multiple filters to help you find the best flight to Santo Domingo from Jacksonville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Jacksonville to Santo Domingo right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Jacksonville to Santo Domingo now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santo Domingo and let you know when they change.

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