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Cheap flights from Jacksonville to Santo Domingo from $172

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Jacksonville to Santo Domingo departing on 5/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Jacksonville to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
3:18 pm - 11:59 pm
JAX
-
SDQ
8h 41m
1 stop
JetBlue Logo
5:01 am - 2:18 pm
SDQ
-
JAX
9h 17m
1 stop
$368JetBlue
Thu, Jul 23 - Sat, Aug 1
American Airlines Logo
6:20 am - 10:55 pm
JAX
-
SDQ
16h 35m
2 stops
American Airlines Logo
7:35 pm - 9:27 am
SDQ
-
JAX
13h 52m
1 stop
$373American Airlines
Tue, Jun 2 - Thu, Jun 11
American Airlines Logo
5:50 pm - 12:45 pm
JAX
-
SDQ
18h 55m
1 stop
American Airlines Logo
7:35 pm - 9:27 am
SDQ
-
JAX
13h 52m
1 stop
$375American Airlines
Wed, Jun 3 - Tue, Jun 16
American Airlines Logo
4:35 pm - 12:45 pm
JAX
-
SDQ
20h 10m
1 stop
American Airlines Logo
7:35 pm - 12:54 pm
SDQ
-
JAX
17h 19m
2 stops
$380American Airlines
Tue, May 26 - Mon, Jun 1
Frontier Logo
3:59 pm - 11:06 am
JAX
-
SDQ
19h 07m
1 stop
Frontier Logo
12:18 pm - 12:19 pm
SDQ
-
JAX
24h 01m
1 stop
$381Frontier
Wed, Jul 1 - Sun, Jul 5
American Airlines Logo
5:50 pm - 12:45 pm
JAX
-
SDQ
18h 55m
1 stop
American Airlines Logo
1:45 pm - 11:09 am
SDQ
-
JAX
21h 24m
1 stop
$383American Airlines
Mon, Jun 8 - Mon, Jun 15
Frontier Logo
3:59 pm - 11:06 am
JAX
-
SDQ
19h 07m
1 stop
Frontier Logo
12:21 pm - 3:04 pm
SDQ
-
JAX
26h 43m
1 stop
$385Frontier
Wed, Jun 10 - Wed, Jun 17
Multiple Airlines Logo
11:20 am - 7:18 pm
JAX
-
SDQ
7h 58m
1 stop
Multiple Airlines Logo
12:41 pm - 12:02 pm
SDQ
-
JAX
23h 21m
1 stop
$395Multiple Airlines
Sun, Sep 6 - Wed, Sep 9
Frontier Logo
3:59 pm - 11:06 am
JAX
-
SDQ
19h 07m
1 stop
Frontier Logo
12:18 pm - 5:33 pm
SDQ
-
JAX
29h 15m
2 stops
$397Frontier
Wed, Jul 1 - Sun, Jul 5
Frontier Logo
1:17 pm - 11:06 am
JAX
-
SDQ
21h 49m
1 stop
Frontier Logo
12:21 pm - 12:22 pm
SDQ
-
JAX
24h 01m
1 stop
$405Frontier
Fri, Jun 12 - Sun, Jun 21

Frontier flights from Jacksonville to Santo Domingo

Our best Frontier deals on Jacksonville to Santo Domingo flight tickets
Frontier
Jul 1
JAX3:59 pmJacksonville
19h 07m
1 stop
SDQ11:06 amSanto Domingo Las Americas
Jul 5
SDQ12:18 pmSanto Domingo Las Americas
24h 01m
1 stop
JAX12:19 pmJacksonville
$381
Frontier
Jun 10
JAX3:59 pmJacksonville
19h 07m
1 stop
SDQ11:06 amSanto Domingo Las Americas
Jun 17
SDQ12:21 pmSanto Domingo Las Americas
26h 43m
1 stop
JAX3:04 pmJacksonville
$385
Frontier
Jul 1
JAX3:59 pmJacksonville
19h 07m
1 stop
SDQ11:06 amSanto Domingo Las Americas
Jul 5
SDQ12:18 pmSanto Domingo Las Americas
29h 15m
2 stops
JAX5:33 pmJacksonville
$397

American Airlines flights from Jacksonville to Santo Domingo

Our best American Airlines deals on Jacksonville to Santo Domingo flight tickets
American Airlines
May 18
JAX6:00 amJacksonville
8h 59m
1 stop
SDQ2:59 pmSanto Domingo Las Americas
Jun 12
SDQ7:35 pmSanto Domingo Las Americas
15h 33m
1 stop
JAX11:08 amJacksonville
$368
American Airlines
May 18
JAX6:00 amJacksonville
16h 55m
2 stops
SDQ10:55 pmSanto Domingo Las Americas
Jun 12
SDQ7:35 pmSanto Domingo Las Americas
15h 33m
1 stop
JAX11:08 amJacksonville
$373
American Airlines
Jun 3
JAX5:50 pmJacksonville
18h 55m
1 stop
SDQ12:45 pmSanto Domingo Las Americas
Jun 16
SDQ7:35 pmSanto Domingo Las Americas
13h 52m
1 stop
JAX9:27 amJacksonville
$375

momondo Fare Finder

 
Customize your flight search to find flights from Jacksonville to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from Jacksonville to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Thu 7/23

3:18 pm-11:59 pm

1 stop8h 41m

Santo Domingo Las Americas

Sat 8/1

5:01 am-2:18 pm

1 stop9h 17m

$368

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Tue 6/2

6:20 am-10:55 pm

2 stops16h 35m

Santo Domingo Las Americas

Thu 6/11

7:35 pm-9:27 am

1 stop13h 52m

$373

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Wed 6/3

5:50 pm-12:45 pm

1 stop18h 55m

Santo Domingo Las Americas

Tue 6/16

7:35 pm-9:27 am

1 stop13h 52m

$375

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Tue 5/26

4:35 pm-12:45 pm

1 stop20h 10m

Santo Domingo Las Americas

Mon 6/1

7:35 pm-12:54 pm

2 stops17h 19m

$380

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Wed 7/1

3:59 pm-11:06 am

1 stop19h 07m

Santo Domingo Las Americas

Sun 7/5

12:18 pm-12:19 pm

1 stop24h 01m

$381

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Mon 6/8

5:50 pm-12:45 pm

1 stop18h 55m

Santo Domingo Las Americas

Mon 6/15

1:45 pm-11:09 am

1 stop21h 24m

$383

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Wed 6/10

3:59 pm-11:06 am

1 stop19h 07m

Santo Domingo Las Americas

Wed 6/17

12:21 pm-3:04 pm

1 stop26h 43m

$385

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Sun 9/6

11:20 am-7:18 pm

1 stop7h 58m

Santo Domingo Las Americas

Wed 9/9

12:41 pm-12:02 pm

1 stop23h 21m

$395

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Wed 7/1

3:59 pm-11:06 am

1 stop19h 07m

Santo Domingo Las Americas

Sun 7/5

12:18 pm-5:33 pm

2 stops29h 15m

$397

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Fri 6/12

1:17 pm-11:06 am

1 stop21h 49m

Santo Domingo Las Americas

Sun 6/21

12:21 pm-12:22 pm

1 stop24h 01m

$405

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Jacksonville to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Jacksonville and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in June, then you should wait until October to fly from Jacksonville, when ticket prices are also cheap, with an average price of $368.

How have Jacksonville to Santo Domingo flight prices changed over time?

As of May 2026, prices for Jacksonville to Santo Domingo flights are approximately 7% more expensive when compared to flights at the same time last year.

When to book flights from Jacksonville to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Jacksonville to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Jacksonville to Santo Domingo (JAX to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Jacksonville to Santo Domingo

Fastest flight time

5h 12m

Direct flights

None
The fastest flight from Jacksonville to Santo Domingo takes 5h 12m
There are no direct flights from Jacksonville to Santo Domingo. There are no popular flight routes from Jacksonville to Santo Domingo.
Search flight deals

Frequently asked questions about flying from Jacksonville to Santo Domingo

  • How far is Jacksonville to Santo Domingo Las Americas by plane?

    Jacksonville and Santo Domingo Las Americas are 1099.6 mi apart from one another. By plane, this route typically takes 5h 12m.

  • When did momondo last update prices for flights from Jacksonville Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Jacksonville Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from Jacksonville Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Jacksonville Airport to Santo Domingo Las Americas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Jacksonville Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents you'll need for your trip to Santo Domingo Las Americas Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santo Domingo Las Americas Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Jacksonville to Santo Domingo?

Best airlines flying from Jacksonville to Santo Domingo

Compare and see reviews for airlines that fly from Jacksonville to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $154Free CancellationRating
7.9
8,450 reviews
Search Delta flights
JetBluePriceFrom $368Free CancellationRating
7.1
2,973 reviews
Search JetBlue flights
American AirlinesPriceFrom $372Free CancellationRating
7.1
11,662 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Jacksonville to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Jacksonville to Santo Domingo for you.

Can I find flights from Jacksonville to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from Jacksonville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Jacksonville to Santo Domingo?

momondo provides multiple filters to help you find the best flight to Santo Domingo from Jacksonville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Jacksonville to Santo Domingo right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Jacksonville to Santo Domingo now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santo Domingo and let you know when they change.

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