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Cheap flights from Jacksonville to Santo Domingo from $162

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Jacksonville to Santo Domingo departing on 1/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Jacksonville to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:27 pm - 3:28 pm
JAX
-
SDQ
20h 01m1 stop
Multiple Airlines Logo
3:32 pm - 4:23 pm
SDQ
-
JAX
25h 51m2 stops
$338Multiple Airlines
Fri, Jan 9 - Fri, Jan 23
JetBlue Logo
4:45 pm - 2:30 pm
JAX
-
SDQ
21h 45m1 stop
JetBlue Logo
9:38 am - 3:58 pm
SDQ
-
JAX
6h 20m1 stop
$378JetBlue
Sat, Apr 4 - Sat, Apr 18
JetBlue Logo
7:10 pm - 1:17 am
JAX
-
SDQ
29h 07m1 stop
JetBlue Logo
4:15 am - 6:15 pm
SDQ
-
JAX
15h 00m1 stop
$422JetBlue
Tue, Jan 20 - Thu, Jan 29
Multiple Airlines Logo
6:27 pm - 3:28 pm
JAX
-
SDQ
20h 01m1 stop
Multiple Airlines Logo
6:15 pm - 11:09 am
SDQ
-
JAX
17h 54m1 stop
$435Multiple Airlines
Fri, Jan 9 - Fri, Jan 23
JetBlue Logo
7:10 pm - 4:50 pm
JAX
-
SDQ
20h 40m2 stops
JetBlue Logo
4:15 am - 6:15 pm
SDQ
-
JAX
15h 00m1 stop
$445JetBlue
Tue, Jan 20 - Thu, Jan 29
JetBlue Logo
10:13 am - 7:49 pm
JAX
-
SDQ
8h 36m1 stop
JetBlue Logo
4:15 am - 6:15 pm
SDQ
-
JAX
15h 00m1 stop
$446JetBlue
Mon, Jan 26 - Tue, Jan 27
JetBlue Logo
7:10 pm - 12:56 am
JAX
-
SDQ
28h 46m1 stop
JetBlue Logo
1:23 pm - 6:15 pm
SDQ
-
JAX
29h 52m2 stops
$448JetBlue
Thu, Jan 22 - Thu, Jan 29
JetBlue Logo
7:35 pm - 8:05 am
JAX
-
SDQ
12h 30m2 stops
JetBlue Logo
9:38 am - 3:58 pm
SDQ
-
JAX
6h 20m1 stop
$449JetBlue
Sat, Apr 4 - Sat, Apr 18
United Airlines Logo
3:05 pm - 11:46 pm
JAX
-
SDQ
7h 41m1 stop
United Airlines Logo
2:53 pm - 10:52 pm
SDQ
-
JAX
8h 59m1 stop
$450United Airlines
Thu, Jan 22 - Mon, Jan 26
Frontier Logo
9:04 pm - 8:19 pm
JAX
-
SDQ
22h 15m2 stops
Frontier Logo
12:35 pm - 8:51 pm
SDQ
-
JAX
9h 16m1 stop
$452Frontier
Thu, Jan 22 - Sun, Jan 25

JetBlue flights from Jacksonville to Santo Domingo

Our best JetBlue deals on Jacksonville to Santo Domingo flight tickets
JetBlue
Apr 4
JAX4:45 pmJacksonville
21h 45m
1 stop
SDQ2:30 pmSanto Domingo Las Americas
Apr 18
SDQ9:38 amSanto Domingo Las Americas
6h 20m
1 stop
JAX3:58 pmJacksonville
$378
Find similar
JetBlue
Jan 20
JAX7:10 pmJacksonville
29h 07m
1 stop
SDQ1:17 amSanto Domingo Las Americas
Jan 29
SDQ4:15 amSanto Domingo Las Americas
15h 00m
1 stop
JAX6:15 pmJacksonville
$422
Find similar
JetBlue
Jan 20
JAX7:10 pmJacksonville
20h 40m
2 stops
SDQ4:50 pmSanto Domingo Las Americas
Jan 29
SDQ4:15 amSanto Domingo Las Americas
15h 00m
1 stop
JAX6:15 pmJacksonville
$445
Find similar

Frontier flights from Jacksonville to Santo Domingo

Our best Frontier deals on Jacksonville to Santo Domingo flight tickets
Frontier
Dec 29
JAX9:00 pmJacksonville
11h 26m
1 stop
SDQ9:26 amSanto Domingo Las Americas
Jan 1
SDQ12:25 pmSanto Domingo Las Americas
9h 55m
1 stop
JAX9:20 pmJacksonville
$413
Find similar
Frontier
Dec 24
JAX9:00 pmJacksonville
21h 27m
1 stop
SDQ7:27 pmSanto Domingo Las Americas
Jan 1
SDQ12:25 pmSanto Domingo Las Americas
9h 55m
1 stop
JAX9:20 pmJacksonville
$424
Find similar
Frontier
Jan 22
JAX9:04 pmJacksonville
22h 15m
2 stops
SDQ8:19 pmSanto Domingo Las Americas
Jan 25
SDQ12:35 pmSanto Domingo Las Americas
9h 16m
1 stop
JAX8:51 pmJacksonville
$452
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Jacksonville to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Jacksonville to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Fri 1/9

6:27 pm-3:28 pm

1 stop20h 01m

Santo Domingo Las Americas

Fri 1/23

3:32 pm-4:23 pm

2 stops25h 51m

$338

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Sat 4/4

4:45 pm-2:30 pm

1 stop21h 45m

Santo Domingo Las Americas

Sat 4/18

9:38 am-3:58 pm

1 stop6h 20m

$378

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Tue 1/20

7:10 pm-1:17 am

1 stop29h 07m

Santo Domingo Las Americas

Thu 1/29

4:15 am-6:15 pm

1 stop15h 00m

$422

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Fri 1/9

6:27 pm-3:28 pm

1 stop20h 01m

Santo Domingo Las Americas

Fri 1/23

6:15 pm-11:09 am

1 stop17h 54m

$435

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Tue 1/20

7:10 pm-4:50 pm

2 stops20h 40m

Santo Domingo Las Americas

Thu 1/29

4:15 am-6:15 pm

1 stop15h 00m

$445

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Mon 1/26

10:13 am-7:49 pm

1 stop8h 36m

Santo Domingo Las Americas

Tue 1/27

4:15 am-6:15 pm

1 stop15h 00m

$446

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Thu 1/22

7:10 pm-12:56 am

1 stop28h 46m

Santo Domingo Las Americas

Thu 1/29

1:23 pm-6:15 pm

2 stops29h 52m

$448

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Sat 4/4

7:35 pm-8:05 am

2 stops12h 30m

Santo Domingo Las Americas

Sat 4/18

9:38 am-3:58 pm

1 stop6h 20m

$449

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Thu 1/22

3:05 pm-11:46 pm

1 stop7h 41m

Santo Domingo Las Americas

Mon 1/26

2:53 pm-10:52 pm

1 stop8h 59m

$450

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Thu 1/22

9:04 pm-8:19 pm

2 stops22h 15m

Santo Domingo Las Americas

Sun 1/25

12:35 pm-8:51 pm

1 stop9h 16m

$452

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Jacksonville to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in June, then you should wait until October to fly from Jacksonville, when ticket prices are also cheap, with an average price of $472.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Sunday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $420. The most expensive day to fly to Santo Domingo is Friday, with ticket prices averaging around $538.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the evening when flights can be purchased for as low as $411. Try not to purchase tickets in the afternoon because they tend to be around $555. Of course, these prices can vary depending on the time of year and what airport you fly to.

How have Jacksonville to Santo Domingo flight prices changed over time?

As of December 2025, prices for Jacksonville to Santo Domingo flights are approximately 35% more expensive when compared to flights at the same time last year.

When to book flights from Jacksonville to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Jacksonville to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Jacksonville to Santo Domingo (JAX to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Jacksonville to Santo Domingo

Fastest flight time

5h 27m

Direct flights

None
The fastest flight from Jacksonville to Santo Domingo takes 5h 27m
There are no direct flights from Jacksonville to Santo Domingo. There are no popular flight routes from Jacksonville to Santo Domingo.
Search flight deals

  • How far is Jacksonville to Santo Domingo Las Americas by plane?

    Jacksonville and Santo Domingo Las Americas are 1099.6 mi apart from one another. By plane, this route typically takes 5h 27m.

  • When did momondo last update prices for flights from Jacksonville Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Jacksonville Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from Jacksonville Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Jacksonville Airport to Santo Domingo Las Americas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Jacksonville Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents you'll need for your trip to Santo Domingo Las Americas Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santo Domingo Las Americas Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Jacksonville to Santo Domingo?

Best airlines flying from Jacksonville to Santo Domingo

Compare and see reviews for airlines that fly from Jacksonville to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $114Free CancellationRating
5.8
3,073 reviews
Search Frontier flights
DeltaPriceFrom $204Free CancellationRating
7.9
8,015 reviews
Search Delta flights
American AirlinesPriceFrom $442Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Jacksonville to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Jacksonville to Santo Domingo for you.

Can I find flights from Jacksonville to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from Jacksonville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Jacksonville to Santo Domingo?

momondo provides multiple filters to help you find the best flight to Santo Domingo from Jacksonville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Jacksonville to Santo Domingo right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Jacksonville to Santo Domingo now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santo Domingo and let you know when they change.

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