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Cheap flights from Jacksonville to Santo Domingo from $181

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Jacksonville to Santo Domingo departing on 5/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Jacksonville to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:18 pm - 10:39 am
JAX
-
SDQ
13h 21m
1 stop
Multiple Airlines Logo
9:38 am - 3:58 pm
SDQ
-
JAX
6h 20m
1 stop
$373Multiple Airlines
Fri, Apr 17 - Wed, Apr 22
Delta Logo
6:30 am - 1:12 pm
JAX
-
SDQ
6h 42m
1 stop
Delta Logo
2:37 pm - 9:48 pm
SDQ
-
JAX
7h 11m
1 stop
$385Delta
Fri, Apr 24 - Wed, Apr 29
American Airlines Logo
6:37 pm - 9:20 am
JAX
-
SDQ
14h 43m
2 stops
American Airlines Logo
2:25 pm - 9:03 am
SDQ
-
JAX
18h 38m
2 stops
$389American Airlines
Fri, Apr 24 - Wed, Apr 29
American Airlines Logo
11:00 am - 4:55 pm
JAX
-
SDQ
5h 55m
1 stop
American Airlines Logo
5:55 pm - 11:59 pm
SDQ
-
JAX
6h 04m
1 stop
$390American Airlines
Thu, May 7 - Sun, May 10
American Airlines Logo
7:44 pm - 10:52 pm
JAX
-
SDQ
27h 08m
1 stop
American Airlines Logo
5:55 pm - 11:59 pm
SDQ
-
JAX
6h 04m
1 stop
$392American Airlines
Wed, Apr 29 - Tue, May 5
American Airlines Logo
6:00 am - 4:55 pm
JAX
-
SDQ
10h 55m
2 stops
American Airlines Logo
4:00 pm - 9:03 am
SDQ
-
JAX
17h 03m
2 stops
$394American Airlines
Thu, May 7 - Sun, May 10
American Airlines Logo
6:00 am - 4:55 pm
JAX
-
SDQ
10h 55m
1 stop
American Airlines Logo
6:00 am - 11:59 pm
SDQ
-
JAX
17h 59m
1 stop
$397American Airlines
Thu, May 7 - Sun, May 10
American Airlines Logo
6:00 am - 4:55 pm
JAX
-
SDQ
10h 55m
1 stop
American Airlines Logo
4:00 pm - 11:59 pm
SDQ
-
JAX
7h 59m
1 stop
$433American Airlines
Thu, Apr 30 - Mon, May 4
American Airlines Logo
11:00 am - 10:52 pm
JAX
-
SDQ
11h 52m
1 stop
American Airlines Logo
2:25 pm - 9:15 pm
SDQ
-
JAX
6h 50m
1 stop
$435American Airlines
Thu, Apr 9 - Tue, Apr 14
American Airlines Logo
11:06 am - 8:30 pm
JAX
-
SDQ
9h 24m
2 stops
American Airlines Logo
7:25 pm - 9:09 am
SDQ
-
JAX
13h 44m
2 stops
$437American Airlines
Tue, Aug 25 - Mon, Aug 31

JetBlue flights from Jacksonville to Santo Domingo

Our best JetBlue deals on Jacksonville to Santo Domingo flight tickets
JetBlue
May 9
JAX6:20 pmJacksonville
7h 34m
1 stop
SDQ1:54 amSanto Domingo Las Americas
May 13
SDQ9:38 amSanto Domingo Las Americas
7h 57m
1 stop
JAX5:35 pmJacksonville
$463
JetBlue
May 9
JAX6:20 pmJacksonville
7h 34m
1 stop
SDQ1:54 amSanto Domingo Las Americas
May 16
SDQ5:01 amSanto Domingo Las Americas
12h 24m
1 stop
JAX5:25 pmJacksonville
$524
JetBlue
Jul 15
JAX7:12 amJacksonville
5h 12m
1 stop
SDQ12:24 pmSanto Domingo Las Americas
Jul 15
SDQ4:25 pmSanto Domingo Las Americas
27h 05m
1 stop
JAX7:30 pmJacksonville
$554

American Airlines flights from Jacksonville to Santo Domingo

Our best American Airlines deals on Jacksonville to Santo Domingo flight tickets
American Airlines
Apr 24
JAX6:37 pmJacksonville
14h 43m
2 stops
SDQ9:20 amSanto Domingo Las Americas
Apr 29
SDQ2:25 pmSanto Domingo Las Americas
18h 38m
2 stops
JAX9:03 amJacksonville
$389
American Airlines
May 7
JAX11:00 amJacksonville
5h 55m
1 stop
SDQ4:55 pmSanto Domingo Las Americas
May 10
SDQ5:55 pmSanto Domingo Las Americas
6h 04m
1 stop
JAX11:59 pmJacksonville
$390
American Airlines
Apr 29
JAX7:44 pmJacksonville
27h 08m
1 stop
SDQ10:52 pmSanto Domingo Las Americas
May 5
SDQ5:55 pmSanto Domingo Las Americas
6h 04m
1 stop
JAX11:59 pmJacksonville
$392

momondo Fare Finder

 
Customize your flight search to find flights from Jacksonville to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 30, 2026.
Use the filters below to find and compare flights from Jacksonville to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Fri 4/17

9:18 pm-10:39 am

1 stop13h 21m

Santo Domingo Las Americas

Wed 4/22

9:38 am-3:58 pm

1 stop6h 20m

$373

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Fri 4/24

6:30 am-1:12 pm

1 stop6h 42m

Santo Domingo Las Americas

Wed 4/29

2:37 pm-9:48 pm

1 stop7h 11m

$385

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Fri 4/24

6:37 pm-9:20 am

2 stops14h 43m

Santo Domingo Las Americas

Wed 4/29

2:25 pm-9:03 am

2 stops18h 38m

$389
Quickest round-trip

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Thu 5/7

11:00 am-4:55 pm

1 stop5h 55m

Santo Domingo Las Americas

Sun 5/10

5:55 pm-11:59 pm

1 stop6h 04m

$390

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Wed 4/29

7:44 pm-10:52 pm

1 stop27h 08m

Santo Domingo Las Americas

Tue 5/5

5:55 pm-11:59 pm

1 stop6h 04m

$392

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Thu 5/7

6:00 am-4:55 pm

2 stops10h 55m

Santo Domingo Las Americas

Sun 5/10

4:00 pm-9:03 am

2 stops17h 03m

$394

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Thu 5/7

6:00 am-4:55 pm

1 stop10h 55m

Santo Domingo Las Americas

Sun 5/10

6:00 am-11:59 pm

1 stop17h 59m

$397

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Thu 4/30

6:00 am-4:55 pm

1 stop10h 55m

Santo Domingo Las Americas

Mon 5/4

4:00 pm-11:59 pm

1 stop7h 59m

$433

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Thu 4/9

11:00 am-10:52 pm

1 stop11h 52m

Santo Domingo Las Americas

Tue 4/14

2:25 pm-9:15 pm

1 stop6h 50m

$435

JacksonvilleSanto Domingo

JAX - SDQ

JAXSDQ

Jacksonville

Tue 8/25

11:06 am-8:30 pm

2 stops9h 24m

Santo Domingo Las Americas

Mon 8/31

7:25 pm-9:09 am

2 stops13h 44m

$437

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Jacksonville to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Jacksonville and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in June, then you should wait until February to fly from Jacksonville, when ticket prices are also cheap, with an average price of $460.

How have Jacksonville to Santo Domingo flight prices changed over time?

As of March 2026, prices for Jacksonville to Santo Domingo flights are approximately 50% more expensive when compared to flights at the same time last year.

When to book flights from Jacksonville to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Jacksonville to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Jacksonville to Santo Domingo (JAX to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Jacksonville to Santo Domingo

Fastest flight time

5h 35m

Direct flights

None
The fastest flight from Jacksonville to Santo Domingo takes 5h 35m
There are no direct flights from Jacksonville to Santo Domingo. There are no popular flight routes from Jacksonville to Santo Domingo.
Search flight deals

  • How far is Jacksonville to Santo Domingo Las Americas by plane?

    Jacksonville and Santo Domingo Las Americas are 1099.6 mi apart from one another. By plane, this route typically takes 5h 35m.

  • When did momondo last update prices for flights from Jacksonville Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Jacksonville Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from Jacksonville Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Jacksonville Airport to Santo Domingo Las Americas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Jacksonville Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents you'll need for your trip to Santo Domingo Las Americas Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santo Domingo Las Americas Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Jacksonville to Santo Domingo?

Best airlines flying from Jacksonville to Santo Domingo

Compare and see reviews for airlines that fly from Jacksonville to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $154Free CancellationRating
7.9
8,358 reviews
Search Delta flights
American AirlinesPriceFrom $424Free CancellationRating
7.1
11,530 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Jacksonville to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Jacksonville to Santo Domingo for you.

Can I find flights from Jacksonville to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from Jacksonville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Jacksonville to Santo Domingo?

momondo provides multiple filters to help you find the best flight to Santo Domingo from Jacksonville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Jacksonville to Santo Domingo right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Jacksonville to Santo Domingo now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santo Domingo and let you know when they change.

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