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Cheap flights from Jacksonville to Santiago de los Caballeros from $272

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Jacksonville to Santiago de los Caballeros departing on 12/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Jacksonville to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
12:12 pm - 12:59 amJAX-STI
11h 47m1 stop
Delta Logo
6:40 am - 10:26 pmSTI-JAX
16h 46m1 stop
$400Delta
Find Deal
Thu, Nov 13 - Wed, Nov 19
American Airlines Logo
6:00 am - 8:51 pmJAX-STI
13h 51m1 stop
American Airlines Logo
4:35 pm - 8:38 amSTI-JAX
17h 03m2 stops
$404American Airlines
Find Deal
Sun, Nov 16 - Thu, Nov 20
JetBlue Logo
10:24 am - 1:58 amJAX-STI
15h 34m1 stop
JetBlue Logo
7:11 am - 8:37 pmSTI-JAX
14h 26m1 stop
$461JetBlue
Find Deal
Sat, Nov 1 - Wed, Nov 5
Delta Logo
11:15 am - 11:27 pmJAX-STI
12h 12m1 stop
Delta Logo
6:00 am - 3:18 pmSTI-JAX
9h 18m1 stop
$465Delta
Find Deal
Mon, Mar 9 - Thu, Mar 12
Delta Logo
8:30 am - 11:27 pmJAX-STI
14h 57m2 stops
Delta Logo
6:00 am - 6:37 pmSTI-JAX
12h 37m1 stop
$469Delta
Find Deal
Mon, Mar 9 - Thu, Mar 12
JetBlue Logo
5:25 pm - 2:53 amJAX-STI
9h 28m1 stop
JetBlue Logo
4:41 am - 8:37 pmSTI-JAX
16h 56m1 stop
$476JetBlue
Find Deal
Fri, Oct 31 - Tue, Nov 4
American Airlines Logo
5:12 am - 8:03 pmJAX-STI
14h 51m2 stops
American Airlines Logo
7:00 am - 11:46 pmSTI-JAX
16h 46m2 stops
$480American Airlines
Find Deal
Mon, Mar 9 - Thu, Mar 12
American Airlines Logo
6:00 am - 3:33 pmJAX-STI
8h 33m1 stop
American Airlines Logo
4:35 pm - 12:14 amSTI-JAX
8h 39m1 stop
$481American Airlines
Find Deal
Thu, Nov 13 - Sun, Nov 23
Multiple Airlines Logo
8:34 am - 10:38 amJAX-STI
26h 04m2 stops
Multiple Airlines Logo
1:17 pm - 9:01 amSTI-JAX
20h 44m2 stops
$482Multiple Airlines
Find Deal
Fri, Oct 31 - Wed, Nov 5
American Airlines Logo
6:00 am - 12:13 pmJAX-STI
6h 13m1 stop
American Airlines Logo
6:20 am - 7:00 pmSTI-JAX
13h 40m1 stop
$494American Airlines
Find Deal
Wed, Oct 29 - Tue, Nov 25

Delta flights from Jacksonville to Santiago de los Caballeros

Our best Delta deals on Jacksonville to Santiago de los Caballeros flight tickets
Delta
Nov 13
JAX12:12 pmJacksonville
11h 47m
1 stop
STI12:59 amSantiago de los Caballeros
Nov 19
STI6:40 amSantiago de los Caballeros
16h 46m
1 stop
JAX10:26 pmJacksonville
$400
Find similar
Delta
Mar 9
JAX11:15 amJacksonville
12h 12m
1 stop
STI11:27 pmSantiago de los Caballeros
Mar 12
STI6:00 amSantiago de los Caballeros
9h 18m
1 stop
JAX3:18 pmJacksonville
$465
Find similar
Delta
Mar 9
JAX8:30 amJacksonville
14h 57m
2 stops
STI11:27 pmSantiago de los Caballeros
Mar 12
STI6:00 amSantiago de los Caballeros
12h 37m
1 stop
JAX6:37 pmJacksonville
$469
Find similar

American Airlines flights from Jacksonville to Santiago de los Caballeros

Our best American Airlines deals on Jacksonville to Santiago de los Caballeros flight tickets
American Airlines
Nov 16
JAX6:00 amJacksonville
13h 51m
1 stop
STI8:51 pmSantiago de los Caballeros
Nov 20
STI4:35 pmSantiago de los Caballeros
17h 03m
2 stops
JAX8:38 amJacksonville
$404
Find similar
American Airlines
Mar 9
JAX5:12 amJacksonville
14h 51m
2 stops
STI8:03 pmSantiago de los Caballeros
Mar 12
STI7:00 amSantiago de los Caballeros
16h 46m
2 stops
JAX11:46 pmJacksonville
$480
Find similar
American Airlines
Nov 13
JAX6:00 amJacksonville
8h 33m
1 stop
STI3:33 pmSantiago de los Caballeros
Nov 23
STI4:35 pmSantiago de los Caballeros
8h 39m
1 stop
JAX12:14 amJacksonville
$481
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Jacksonville to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Jacksonville to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Thu 11/13

12:12 pm-12:59 am

1 stop11h 47m

Santiago de los Caballeros

Wed 11/19

6:40 am-10:26 pm

1 stop16h 46m

$400

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Sun 11/16

6:00 am-8:51 pm

1 stop13h 51m

Santiago de los Caballeros

Thu 11/20

4:35 pm-8:38 am

2 stops17h 03m

$404

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Sat 11/1

10:24 am-1:58 am

1 stop15h 34m

Santiago de los Caballeros

Wed 11/5

7:11 am-8:37 pm

1 stop14h 26m

$461

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Mon 3/9

11:15 am-11:27 pm

1 stop12h 12m

Santiago de los Caballeros

Thu 3/12

6:00 am-3:18 pm

1 stop9h 18m

$465

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Mon 3/9

8:30 am-11:27 pm

2 stops14h 57m

Santiago de los Caballeros

Thu 3/12

6:00 am-6:37 pm

1 stop12h 37m

$469

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Fri 10/31

5:25 pm-2:53 am

1 stop9h 28m

Santiago de los Caballeros

Tue 11/4

4:41 am-8:37 pm

1 stop16h 56m

$476

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Mon 3/9

5:12 am-8:03 pm

2 stops14h 51m

Santiago de los Caballeros

Thu 3/12

7:00 am-11:46 pm

2 stops16h 46m

$480

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Thu 11/13

6:00 am-3:33 pm

1 stop8h 33m

Santiago de los Caballeros

Sun 11/23

4:35 pm-12:14 am

1 stop8h 39m

$481

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Fri 10/31

8:34 am-10:38 am

2 stops26h 04m

Santiago de los Caballeros

Wed 11/5

1:17 pm-9:01 am

2 stops20h 44m

$482

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Wed 10/29

6:00 am-12:13 pm

1 stop6h 13m

Santiago de los Caballeros

Tue 11/25

6:20 am-7:00 pm

1 stop13h 40m

$494

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Jacksonville to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santiago de los Caballeros?

The cheapest day to depart from Jacksonville to Santiago de los Caballeros is on a Thursday when prices can be found for as low as $469. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Jacksonville to Santiago de los Caballeros for around $834.

What is the cheapest time of day to depart on your flight to Santiago de los Caballeros?

Our data shows that the cheapest Jacksonville to Santiago de los Caballeros flights are usually those with departure times in the morning. Our users have found flights to Santiago de los Caballeros in the morning for as low as $485. In the afternoon is when there is more demand to fly to Santiago de los Caballeros, so prices are often more expensive at around $644 per ticket.

When to book flights from Jacksonville to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Jacksonville to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Jacksonville to Santiago de los Caballeros (JAX to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Jacksonville to Santiago de los Caballeros

Direct flights

None
There are no direct flights from Jacksonville to Santiago de los Caballeros. There are no popular flight routes from Jacksonville to Santiago de los Caballeros.
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  • How far is Jacksonville to Santiago de los Caballeros by plane?

    There are 1016.3 mi between Jacksonville and Santiago de los Caballeros. By plane, this route typically takes 6h 13m.

  • When did momondo last update prices for flights from Jacksonville Airport to Santiago de los Caballeros Airport?

    Prices for flights from Jacksonville Airport to Santiago de los Caballeros Airport were last updated today.

  • How many operators does momondo search for flights from Jacksonville Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Jacksonville Airport to Santiago de los Caballeros Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Jacksonville Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents you'll need for your trip to Santiago de los Caballeros Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago de los Caballeros Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Jacksonville to Santiago de los Caballeros?

Best airlines flying from Jacksonville to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Jacksonville to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $437Free CancellationRating
7.2
11,043 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Jacksonville to Santiago de los Caballeros?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago de los Caballeros from Jacksonville.

Can I find flights from Jacksonville to Santiago de los Caballeros with flexible booking policies on momondo?

All flight searches from Jacksonville to Santiago de los Caballeros on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Jacksonville to Santiago de los Caballeros?

momondo helps you find the best flight between Jacksonville and Santiago de los Caballeros by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Jacksonville to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Price alerts on flights to Santiago de los Caballeros from Jacksonville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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