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Cheap flights from Jacksonville to Santiago de los Caballeros from $150

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Jacksonville to Santiago de los Caballeros departing on 2/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Jacksonville to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
9:43 am - 8:29 pm
JAX
-
STI
10h 46m
1 stop
American Airlines Logo
7:00 am - 7:08 pm
STI
-
JAX
12h 08m
1 stop
$331American Airlines
Wed, Mar 18 - Wed, Mar 25
American Airlines Logo
6:09 pm - 1:31 pm
JAX
-
STI
18h 22m
2 stops
American Airlines Logo
2:31 pm - 8:51 am
STI
-
JAX
19h 20m
2 stops
$335American Airlines
Thu, Feb 26 - Wed, Mar 4
American Airlines Logo
8:10 pm - 9:30 pm
JAX
-
STI
24h 20m
1 stop
American Airlines Logo
2:31 pm - 8:51 am
STI
-
JAX
19h 20m
2 stops
$342American Airlines
Thu, Feb 26 - Thu, Mar 5
American Airlines Logo
8:10 pm - 9:30 pm
JAX
-
STI
24h 20m
1 stop
American Airlines Logo
8:00 am - 11:59 pm
STI
-
JAX
16h 59m
1 stop
$344American Airlines
Thu, Feb 26 - Thu, Mar 5
American Airlines Logo
6:00 am - 9:30 pm
JAX
-
STI
14h 30m
1 stop
American Airlines Logo
8:00 am - 11:59 pm
STI
-
JAX
16h 59m
1 stop
$394American Airlines
Wed, Feb 18 - Sun, Feb 22
American Airlines Logo
7:02 am - 9:30 pm
JAX
-
STI
13h 28m
2 stops
American Airlines Logo
8:00 am - 9:03 am
STI
-
JAX
26h 03m
1 stop
$398American Airlines
Wed, Feb 18 - Sun, Feb 22
American Airlines Logo
8:05 pm - 12:30 pm
JAX
-
STI
16h 25m
1 stop
American Airlines Logo
7:00 am - 9:03 am
STI
-
JAX
26h 03m
1 stop
$406American Airlines
Mon, Mar 16 - Fri, Mar 20
American Airlines Logo
6:00 am - 9:30 pm
JAX
-
STI
14h 30m
1 stop
American Airlines Logo
8:00 am - 10:38 pm
STI
-
JAX
15h 38m
1 stop
$408American Airlines
Fri, Feb 13 - Tue, Feb 17
American Airlines Logo
6:00 am - 9:30 pm
JAX
-
STI
14h 30m
1 stop
American Airlines Logo
2:31 pm - 10:01 am
STI
-
JAX
20h 30m
2 stops
$412American Airlines
Fri, Feb 13 - Tue, Feb 17
American Airlines Logo
6:00 am - 12:23 pm
JAX
-
STI
6h 23m
1 stop
American Airlines Logo
1:32 pm - 9:03 am
STI
-
JAX
19h 31m
2 stops
$449American Airlines
Fri, Apr 24 - Sat, May 2

JetBlue flights from Jacksonville to Santiago de los Caballeros

Our best JetBlue deals on Jacksonville to Santiago de los Caballeros flight tickets
JetBlue
Apr 30
JAX6:10 amJacksonville
18h 17m
1 stop
STI12:27 amSantiago de los Caballeros
May 7
STI4:22 pmSantiago de los Caballeros
23h 36m
1 stop
JAX3:58 pmJacksonville
$499
JetBlue
Apr 24
JAX6:10 amJacksonville
18h 17m
1 stop
STI12:27 amSantiago de los Caballeros
May 2
STI7:00 amSantiago de los Caballeros
14h 19m
1 stop
JAX9:19 pmJacksonville
$509
JetBlue
Mar 12
JAX6:42 pmJacksonville
7h 05m
1 stop
STI1:47 amSantiago de los Caballeros
Mar 19
STI9:13 amSantiago de los Caballeros
6h 31m
1 stop
JAX3:44 pmJacksonville
$514

American Airlines flights from Jacksonville to Santiago de los Caballeros

Our best American Airlines deals on Jacksonville to Santiago de los Caballeros flight tickets
American Airlines
Mar 18
JAX9:43 amJacksonville
10h 46m
1 stop
STI8:29 pmSantiago de los Caballeros
Mar 25
STI7:00 amSantiago de los Caballeros
12h 08m
1 stop
JAX7:08 pmJacksonville
$331
American Airlines
Feb 26
JAX6:09 pmJacksonville
18h 22m
2 stops
STI1:31 pmSantiago de los Caballeros
Mar 4
STI2:31 pmSantiago de los Caballeros
19h 20m
2 stops
JAX8:51 amJacksonville
$335
American Airlines
Feb 26
JAX8:10 pmJacksonville
24h 20m
1 stop
STI9:30 pmSantiago de los Caballeros
Mar 5
STI2:31 pmSantiago de los Caballeros
19h 20m
2 stops
JAX8:51 amJacksonville
$342

momondo Fare Finder

 
Customize your flight search to find flights from Jacksonville to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Jacksonville to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Wed 3/18

9:43 am-8:29 pm

1 stop10h 46m

Santiago de los Caballeros

Wed 3/25

7:00 am-7:08 pm

1 stop12h 08m

$331

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Thu 2/26

6:09 pm-1:31 pm

2 stops18h 22m

Santiago de los Caballeros

Wed 3/4

2:31 pm-8:51 am

2 stops19h 20m

$335

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Thu 2/26

8:10 pm-9:30 pm

1 stop24h 20m

Santiago de los Caballeros

Thu 3/5

2:31 pm-8:51 am

2 stops19h 20m

$342

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Thu 2/26

8:10 pm-9:30 pm

1 stop24h 20m

Santiago de los Caballeros

Thu 3/5

8:00 am-11:59 pm

1 stop16h 59m

$344

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Wed 2/18

6:00 am-9:30 pm

1 stop14h 30m

Santiago de los Caballeros

Sun 2/22

8:00 am-11:59 pm

1 stop16h 59m

$394

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Wed 2/18

7:02 am-9:30 pm

2 stops13h 28m

Santiago de los Caballeros

Sun 2/22

8:00 am-9:03 am

1 stop26h 03m

$398

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Mon 3/16

8:05 pm-12:30 pm

1 stop16h 25m

Santiago de los Caballeros

Fri 3/20

7:00 am-9:03 am

1 stop26h 03m

$406

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Fri 2/13

6:00 am-9:30 pm

1 stop14h 30m

Santiago de los Caballeros

Tue 2/17

8:00 am-10:38 pm

1 stop15h 38m

$408

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Fri 2/13

6:00 am-9:30 pm

1 stop14h 30m

Santiago de los Caballeros

Tue 2/17

2:31 pm-10:01 am

2 stops20h 30m

$412

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

Fri 4/24

6:00 am-12:23 pm

1 stop6h 23m

Santiago de los Caballeros

Sat 5/2

1:32 pm-9:03 am

2 stops19h 31m

$449

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Jacksonville to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Jacksonville to Santiago de los Caballeros?

American Airlines and Delta are the most popular carriers operating from Jacksonville to Santiago de los Caballeros

What airlines fly to Santiago de los Caballeros?

American Airlines, Delta and Frontier are the top three most popular airlines that fly to Santiago de los Caballeros from Jacksonville according to our data. American Airlines is the first choice among our users, with 85% of people opting to fly with this airline when traveling to Santiago de los Caballeros. Keep in mind that there are 3 different airlines that fly to Santiago de los Caballeros on a routine basis, so you have a few additional options to choose from.

When to book flights from Jacksonville to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Jacksonville to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Jacksonville to Santiago de los Caballeros (JAX to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Jacksonville to Santiago de los Caballeros

Fastest flight time

7h 05m

Direct flights

None
The fastest flight from Jacksonville to Santiago de los Caballeros takes 7h 05m
There are no direct flights from Jacksonville to Santiago de los Caballeros. There are no popular flight routes from Jacksonville to Santiago de los Caballeros.
Search flight deals

  • How far is Jacksonville to Santiago de los Caballeros by plane?

    There are 1016.3 mi between Jacksonville and Santiago de los Caballeros. By plane, this route typically takes 7h 05m.

  • When did momondo last update prices for flights from Jacksonville Airport to Santiago de los Caballeros Airport?

    Prices for flights from Jacksonville Airport to Santiago de los Caballeros Airport were last updated today.

  • How many operators does momondo search for flights from Jacksonville Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Jacksonville Airport to Santiago de los Caballeros Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Jacksonville Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents you'll need for your trip to Santiago de los Caballeros Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago de los Caballeros Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Jacksonville to Santiago de los Caballeros?

Best airlines flying from Jacksonville to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Jacksonville to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $399Free CancellationRating
7.2
11,201 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Jacksonville to Santiago de los Caballeros?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago de los Caballeros from Jacksonville.

Can I find flights from Jacksonville to Santiago de los Caballeros with flexible booking policies on momondo?

All flight searches from Jacksonville to Santiago de los Caballeros on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Jacksonville to Santiago de los Caballeros?

momondo helps you find the best flight between Jacksonville and Santiago de los Caballeros by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Jacksonville to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Price alerts on flights to Santiago de los Caballeros from Jacksonville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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