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Cheap flights from Jacksonville to Santiago de los Caballeros from $443

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Jacksonville to Santiago de los Caballeros departing on 9/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Jacksonville to Santiago de los Caballeros

Cheap round-trip flights

American Airlines Logo
6:00 am - 12:27 pmJAX-STI
6h 27m1 stop
American Airlines Logo
1:29 pm - 6:52 pmSTI-JAX
5h 23m1 stop
$443American Airlines
Find Deal
vie., sep. 12 - mar., sep. 16
Delta Logo
7:05 am - 7:06 pmJAX-STI
12h 01m1 stop
Delta Logo
9:59 pm - 10:40 amSTI-JAX
13h 41m1 stop
$444Delta
Find Deal
mar., oct. 14 - mié., dic. 10
Delta Logo
7:51 pm - 12:40 pmJAX-STI
16h 49m2 stops
Delta Logo
8:40 pm - 10:43 amSTI-JAX
14h 03m1 stop
$447Delta
Find Deal
vie., sep. 12 - mar., sep. 16
Delta Logo
7:10 pm - 12:03 pmJAX-STI
16h 53m2 stops
Delta Logo
6:45 am - 3:34 pmSTI-JAX
9h 49m1 stop
$449Delta
Find Deal
mar., oct. 14 - mié., dic. 10
JetBlue Logo
6:35 am - 9:27 pmJAX-STI
14h 52m1 stop
JetBlue Logo
3:20 am - 4:17 pmSTI-JAX
12h 57m1 stop
$452JetBlue
Find Deal
vie., sep. 12 - lun., sep. 15
JetBlue Logo
5:12 pm - 9:27 pmJAX-STI
28h 15m1 stop
JetBlue Logo
3:20 am - 4:17 pmSTI-JAX
12h 57m1 stop
$461JetBlue
Find Deal
vie., sep. 12 - lun., sep. 15
JetBlue Logo
6:35 am - 2:13 pmJAX-STI
7h 38m1 stop
JetBlue Logo
9:55 am - 11:05 pmSTI-JAX
13h 10m1 stop
$526JetBlue
Find Deal
lun., oct. 6 - vie., oct. 10
JetBlue Logo
5:13 pm - 2:21 amJAX-STI
9h 08m1 stop
JetBlue Logo
3:20 am - 4:17 pmSTI-JAX
12h 57m1 stop
$552JetBlue
Find Deal
sáb., sep. 27 - vie., oct. 10
American Airlines Logo
7:00 am - 12:31 pmJAX-STI
5h 31m1 stop
American Airlines Logo
1:31 pm - 11:49 pmSTI-JAX
10h 18m1 stop
$664American Airlines
Find Deal
vie., ago. 29 - dom., ago. 31
American Airlines Logo
6:30 am - 8:48 pmJAX-STI
14h 18m2 stops
American Airlines Logo
1:31 pm - 11:49 pmSTI-JAX
10h 18m1 stop
$668American Airlines
Find Deal
vie., ago. 29 - dom., ago. 31

JetBlue flights from Jacksonville to Santiago de los Caballeros

Our best JetBlue deals on Jacksonville to Santiago de los Caballeros flight tickets
JetBlue
Sep 12
JAX6:35 amJacksonville
14h 52m
1 stop
STI9:27 pmSantiago de los Caballeros
Sep 15
STI3:20 amSantiago de los Caballeros
12h 57m
1 stop
JAX4:17 pmJacksonville
$452
Find similar
JetBlue
Sep 12
JAX5:12 pmJacksonville
28h 15m
1 stop
STI9:27 pmSantiago de los Caballeros
Sep 15
STI3:20 amSantiago de los Caballeros
12h 57m
1 stop
JAX4:17 pmJacksonville
$461
Find similar
JetBlue
Oct 6
JAX6:35 amJacksonville
7h 38m
1 stop
STI2:13 pmSantiago de los Caballeros
Oct 10
STI9:55 amSantiago de los Caballeros
13h 10m
1 stop
JAX11:05 pmJacksonville
$526
Find similar

Delta flights from Jacksonville to Santiago de los Caballeros

Our best Delta deals on Jacksonville to Santiago de los Caballeros flight tickets
Delta
Oct 14
JAX7:05 amJacksonville
12h 01m
1 stop
STI7:06 pmSantiago de los Caballeros
Dec 10
STI9:59 pmSantiago de los Caballeros
13h 41m
1 stop
JAX10:40 amJacksonville
$444
Find similar
Delta
Sep 12
JAX7:51 pmJacksonville
16h 49m
2 stops
STI12:40 pmSantiago de los Caballeros
Sep 16
STI8:40 pmSantiago de los Caballeros
14h 03m
1 stop
JAX10:43 amJacksonville
$447
Find similar
Delta
Oct 14
JAX7:10 pmJacksonville
16h 53m
2 stops
STI12:03 pmSantiago de los Caballeros
Dec 10
STI6:45 amSantiago de los Caballeros
9h 49m
1 stop
JAX3:34 pmJacksonville
$449
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Jacksonville to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated agosto 19, 2025.
Use the filters below to find and compare flights from Jacksonville to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

vie. 9/12

6:00 am-12:27 pm

1 stop6h 27m

Santiago de los Caballeros

mar. 9/16

1:29 pm-6:52 pm

1 stop5h 23m

$443

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

mar. 10/14

7:05 am-7:06 pm

1 stop12h 01m

Santiago de los Caballeros

mié. 12/10

9:59 pm-10:40 am

1 stop13h 41m

$444

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

vie. 9/12

7:51 pm-12:40 pm

2 stops16h 49m

Santiago de los Caballeros

mar. 9/16

8:40 pm-10:43 am

1 stop14h 03m

$447

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

mar. 10/14

7:10 pm-12:03 pm

2 stops16h 53m

Santiago de los Caballeros

mié. 12/10

6:45 am-3:34 pm

1 stop9h 49m

$449

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

vie. 9/12

6:35 am-9:27 pm

1 stop14h 52m

Santiago de los Caballeros

lun. 9/15

3:20 am-4:17 pm

1 stop12h 57m

$452

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

vie. 9/12

5:12 pm-9:27 pm

1 stop28h 15m

Santiago de los Caballeros

lun. 9/15

3:20 am-4:17 pm

1 stop12h 57m

$461

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

lun. 10/6

6:35 am-2:13 pm

1 stop7h 38m

Santiago de los Caballeros

vie. 10/10

9:55 am-11:05 pm

1 stop13h 10m

$526

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

sáb. 9/27

5:13 pm-2:21 am

1 stop9h 08m

Santiago de los Caballeros

vie. 10/10

3:20 am-4:17 pm

1 stop12h 57m

$552

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

vie. 8/29

7:00 am-12:31 pm

1 stop5h 31m

Santiago de los Caballeros

dom. 8/31

1:31 pm-11:49 pm

1 stop10h 18m

$664

JacksonvilleSantiago de los Caballeros

JAX - STI

JAXSTI

Jacksonville

vie. 8/29

6:30 am-8:48 pm

2 stops14h 18m

Santiago de los Caballeros

dom. 8/31

1:31 pm-11:49 pm

1 stop10h 18m

$668

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Jacksonville to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santiago de los Caballeros?

The cheapest day to depart from Jacksonville to Santiago de los Caballeros is on a Thursday when prices can be found for as low as $469. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Jacksonville to Santiago de los Caballeros for around $834.

What is the cheapest time of day to depart on your flight to Santiago de los Caballeros?

Our data shows that the cheapest Jacksonville to Santiago de los Caballeros flights are usually those with departure times in the morning. Our users have found flights to Santiago de los Caballeros in the morning for as low as $485. In the afternoon is when there is more demand to fly to Santiago de los Caballeros, so prices are often more expensive at around $644 per ticket.

When to book flights from Jacksonville to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Jacksonville to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Jacksonville to Santiago de los Caballeros (JAX to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Jacksonville to Santiago de los Caballeros

Best Price Found

$443

Fastest flight time

5h 31m

Direct flights

None

Airports in Santiago de los Caballeros

1 airport
The best flight deal from Jacksonville to Santiago de los Caballeros found on momondo in the last 72 hours is $443
The fastest flight from Jacksonville to Santiago de los Caballeros takes 5h 31m
There are no direct flights from Jacksonville to Santiago de los Caballeros. Popular non-direct route for this connection is Jacksonville Airport - Santiago de los Caballeros Airport.
There is 1 airport near Santiago de los Caballeros: Santiago de los Caballeros (STI)
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  • How far is Jacksonville to Santiago de los Caballeros by plane?

    There are 1016.3 mi between Jacksonville and Santiago de los Caballeros. By plane, this route typically takes 5h 31m.

  • When did momondo last update prices for flights from Jacksonville Airport to Santiago de los Caballeros Airport?

    Prices for flights from Jacksonville Airport to Santiago de los Caballeros Airport were last updated today.

  • How many operators does momondo search for flights from Jacksonville Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Jacksonville Airport to Santiago de los Caballeros Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Jacksonville Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents you'll need for your trip to Santiago de los Caballeros Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago de los Caballeros Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Jacksonville to Santiago de los Caballeros?

Best airlines flying from Jacksonville to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Jacksonville to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $411Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Jacksonville to Santiago de los Caballeros?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago de los Caballeros from Jacksonville.

Can I find flights from Jacksonville to Santiago de los Caballeros with flexible booking policies on momondo?

All flight searches from Jacksonville to Santiago de los Caballeros on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Jacksonville to Santiago de los Caballeros?

momondo helps you find the best flight between Jacksonville and Santiago de los Caballeros by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Jacksonville to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Price alerts on flights to Santiago de los Caballeros from Jacksonville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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