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Cheap flights from Iowa to Panama City from $269

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to Panama City departing on 4/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Iowa to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
8:04 am - 6:37 pm
DSM
-
PTY
10h 33m
2 stops
United Airlines Logo
7:55 am - 10:43 pm
PTY
-
DSM
14h 48m
1 stop
$504United Airlines
Tue, Apr 7 - Tue, Apr 14
United Airlines Logo
7:52 am - 5:07 pm
DSM
-
PTY
8h 15m
1 stop
United Airlines Logo
7:55 am - 10:44 pm
PTY
-
DSM
14h 49m
1 stop
$513United Airlines
Wed, Mar 4 - Tue, Mar 17
United Airlines Logo
8:00 am - 4:10 am
DSM
-
PTY
20h 10m
2 stops
United Airlines Logo
7:55 am - 10:44 pm
PTY
-
DSM
14h 49m
1 stop
$517United Airlines
Sun, Mar 8 - Tue, Mar 17
United Airlines Logo
7:15 am - 6:38 pm
DSM
-
PTY
11h 23m
1 stop
United Airlines Logo
3:41 pm - 2:18 pm
PTY
-
DSM
22h 37m
1 stop
$522United Airlines
Fri, Mar 20 - Thu, Mar 26
Copa Airlines Logo
8:00 am - 6:37 pm
DSM
-
PTY
10h 37m
1 stop
Copa Airlines Logo
3:20 pm - 2:20 pm
PTY
-
DSM
23h 00m
1 stop
$524Copa Airlines
Fri, Aug 14 - Thu, Aug 20
United Airlines Logo
2:59 pm - 1:45 pm
DSM
-
PTY
22h 46m
1 stop
United Airlines Logo
10:55 pm - 2:25 pm
PTY
-
DSM
15h 30m
2 stops
$527United Airlines
Sat, Mar 21 - Wed, Apr 1
American Airlines Logo
7:05 pm - 12:46 pm
DSM
-
PTY
17h 41m
2 stops
American Airlines Logo
1:49 pm - 11:26 am
PTY
-
DSM
21h 37m
2 stops
$536American Airlines
Wed, Apr 8 - Wed, Apr 15
LATAM Airlines Logo
5:45 am - 1:07 pm
CID
-
PTY
7h 22m
1 stop
LATAM Airlines Logo
2:20 pm - 10:19 pm
PTY
-
CID
31h 59m
2 stops
$745LATAM Airlines
Thu, Jul 30 - Tue, Aug 4
American Airlines Logo
6:40 pm - 12:40 pm
CID
-
PTY
18h 00m
2 stops
American Airlines Logo
1:40 pm - 9:13 am
PTY
-
CID
19h 33m
2 stops
$911American Airlines
Sun, Mar 15 - Fri, Mar 20
Multiple Airlines Logo
6:59 pm - 8:19 pm
CID
-
PTY
24h 20m
1 stop
Multiple Airlines Logo
12:33 pm - 1:38 pm
PTY
-
CID
25h 05m
2 stops
$1,024Multiple Airlines
Fri, Mar 6 - Sat, Mar 14

Copa Airlines flights from Iowa to Panama City

Our best Copa Airlines deals on Iowa to Panama City flight tickets
Copa Airlines
Aug 14
DSM8:00 amDes Moines
10h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Aug 20
PTY3:20 pmPanama City Tocumen Intl
23h 00m
1 stop
DSM2:20 pmDes Moines
$524
Copa Airlines
Mar 8
DSM7:00 amDes Moines
30h 45m
1 stop
PTY1:45 pmPanama City Tocumen Intl
Apr 1
PTY10:00 amPanama City Tocumen Intl
12h 43m
1 stop
DSM10:43 pmDes Moines
$556
Copa Airlines
Mar 12
OMA9:08 amOmaha Eppley Airfield
28h 37m
2 stops
PTY1:45 pmPanama City Tocumen Intl
Mar 16
PTY3:41 pmPanama City Tocumen Intl
27h 13m
1 stop
OMA6:54 pmOmaha Eppley Airfield
$691

United Airlines flights from Iowa to Panama City

Our best United Airlines deals on Iowa to Panama City flight tickets
United Airlines
Apr 7
DSM8:04 amDes Moines
10h 33m
2 stops
PTY6:37 pmPanama City Tocumen Intl
Apr 14
PTY7:55 amPanama City Tocumen Intl
14h 48m
1 stop
DSM10:43 pmDes Moines
$504
United Airlines
Mar 4
DSM7:52 amDes Moines
8h 15m
1 stop
PTY5:07 pmPanama City Tocumen Intl
Mar 17
PTY7:55 amPanama City Tocumen Intl
14h 49m
1 stop
DSM10:44 pmDes Moines
$513
United Airlines
Mar 8
DSM8:00 amDes Moines
20h 10m
2 stops
PTY4:10 amPanama City Tocumen Intl
Mar 17
PTY7:55 amPanama City Tocumen Intl
14h 49m
1 stop
DSM10:44 pmDes Moines
$517

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 22, 2026.
Use the filters below to find and compare flights from Iowa to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Tue 4/7

8:04 am-6:37 pm

2 stops10h 33m

Panama City Tocumen Intl

Tue 4/14

7:55 am-10:43 pm

1 stop14h 48m

$504

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Wed 3/4

7:52 am-5:07 pm

1 stop8h 15m

Panama City Tocumen Intl

Tue 3/17

7:55 am-10:44 pm

1 stop14h 49m

$513

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 3/8

8:00 am-4:10 am

2 stops20h 10m

Panama City Tocumen Intl

Tue 3/17

7:55 am-10:44 pm

1 stop14h 49m

$517

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Fri 3/20

7:15 am-6:38 pm

1 stop11h 23m

Panama City Tocumen Intl

Thu 3/26

3:41 pm-2:18 pm

1 stop22h 37m

$522

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Fri 8/14

8:00 am-6:37 pm

1 stop10h 37m

Panama City Tocumen Intl

Thu 8/20

3:20 pm-2:20 pm

1 stop23h 00m

$524

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 3/21

2:59 pm-1:45 pm

1 stop22h 46m

Panama City Tocumen Intl

Wed 4/1

10:55 pm-2:25 pm

2 stops15h 30m

$527

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Wed 4/8

7:05 pm-12:46 pm

2 stops17h 41m

Panama City Tocumen Intl

Wed 4/15

1:49 pm-11:26 am

2 stops21h 37m

$536

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Thu 7/30

5:45 am-1:07 pm

1 stop7h 22m

Panama City Tocumen Intl

Tue 8/4

2:20 pm-10:19 pm

2 stops31h 59m

$745

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Sun 3/15

6:40 pm-12:40 pm

2 stops18h 00m

Panama City Tocumen Intl

Fri 3/20

1:40 pm-9:13 am

2 stops19h 33m

$911

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Fri 3/6

6:59 pm-8:19 pm

1 stop24h 20m

Panama City Tocumen Intl

Sat 3/14

12:33 pm-1:38 pm

2 stops25h 05m

$1,024

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Iowa to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from Iowa to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $441. If you’re not able to fly to Panama City in September, then July is your next best option. Flight prices from Iowa to Panama City during July average around $455.

Can stopping save me money on Iowa to Panama City flights?

You could potentially save up to 13% on your flight if you consider stops on a Iowa to Panama City flight.

Cheap Iowa to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Panama City

Fastest flight time

7h 52m

Direct flights

None
The fastest flight from Iowa to Panama City takes 7h 52m
There are no direct flights from Iowa to Panama City. There are no popular flight routes from Iowa to Panama City.
Search flight deals

  • When did momondo last update prices for flights from Iowa to Panama City Tocumen Intl Airport?

    Prices for flights from Iowa to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from Iowa to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Iowa to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Iowa to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Iowa to Panama City

Compare and see reviews for airlines that fly from Iowa to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $364Free CancellationRating
7.9
8,241 reviews
Search Delta flights
United AirlinesPriceFrom $441Free CancellationRating
7.4
9,341 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Panama City?

Finding the right flight to Panama City from Iowa is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Iowa to Panama City with flexible booking policies on momondo?

Flights from Iowa to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Iowa to Panama City?

Once all potential Iowa to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Iowa to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Iowa are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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