Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Iowa to Panama City from $268

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to Panama City departing on 1/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Iowa to Panama City

Cheap round-trip flights

United Airlines Logo
6:50 pm - 7:38 pmDSM-PTY
23h 48m2 stops
United Airlines Logo
8:55 am - 10:20 pmPTY-DSM
14h 25m1 stop
$454United Airlines
Find Deal
jue., nov. 6 - jue., nov. 13
United Airlines Logo
6:50 pm - 7:38 pmDSM-PTY
23h 48m2 stops
United Airlines Logo
8:55 am - 10:20 pmPTY-DSM
14h 25m1 stop
$457United Airlines
Find Deal
jue., nov. 6 - jue., nov. 13
Delta Logo
5:47 am - 12:56 pmDSM-PTY
7h 09m1 stop
Delta Logo
2:21 pm - 10:30 pmPTY-DSM
8h 09m1 stop
$461Delta
Find Deal
dom., oct. 12 - mié., oct. 22
Delta Logo
5:47 am - 12:56 pmDSM-PTY
7h 09m1 stop
Delta Logo
2:21 pm - 9:20 amPTY-DSM
18h 59m2 stops
$466Delta
Find Deal
dom., oct. 12 - mié., oct. 22
American Airlines Logo
5:04 pm - 1:49 pmDSM-PTY
19h 45m2 stops
American Airlines Logo
2:49 pm - 3:33 pmPTY-DSM
25h 44m2 stops
$467American Airlines
Find Deal
vie., nov. 7 - vie., nov. 14
American Airlines Logo
5:04 pm - 1:49 pmDSM-PTY
19h 45m2 stops
American Airlines Logo
2:49 pm - 1:31 pmPTY-DSM
23h 42m2 stops
$468American Airlines
Find Deal
vie., nov. 7 - vie., nov. 14
Delta Logo
5:15 pm - 12:56 pmDSM-PTY
19h 41m1 stop
Delta Logo
2:21 pm - 10:30 pmPTY-DSM
8h 09m1 stop
$470Delta
Find Deal
sáb., oct. 11 - mar., oct. 21
United Airlines Logo
3:05 pm - 6:37 pmDSM-PTY
27h 32m1 stop
United Airlines Logo
3:30 pm - 10:32 amPTY-DSM
19h 02m2 stops
$475United Airlines
Find Deal
sáb., oct. 11 - lun., oct. 20
Multiple Airlines Logo
10:41 am - 8:19 pmDSM-PTY
9h 38m1 stop
Multiple Airlines Logo
12:03 pm - 9:51 amPTY-DSM
21h 48m1 stop
$519Multiple Airlines
Find Deal
dom., oct. 12 - sáb., oct. 18
Multiple Airlines Logo
10:41 am - 8:19 pmDSM-PTY
9h 38m1 stop
Multiple Airlines Logo
12:03 pm - 9:51 amPTY-DSM
21h 48m1 stop
$525Multiple Airlines
Find Deal
dom., oct. 12 - sáb., oct. 18

United Airlines flights from Iowa to Panama City

Our best United Airlines deals on Iowa to Panama City flight tickets
United Airlines
Nov 6
DSM6:50 pmDes Moines
23h 48m
2 stops
PTY7:38 pmPanama City Tocumen Intl
Nov 13
PTY8:55 amPanama City Tocumen Intl
14h 25m
1 stop
DSM10:20 pmDes Moines
$454
Find similar
United Airlines
Nov 6
DSM6:50 pmDes Moines
23h 48m
2 stops
PTY7:38 pmPanama City Tocumen Intl
Nov 13
PTY8:55 amPanama City Tocumen Intl
14h 25m
1 stop
DSM10:20 pmDes Moines
$457
Find similar
United Airlines
Oct 11
DSM3:05 pmDes Moines
27h 32m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Oct 20
PTY3:30 pmPanama City Tocumen Intl
19h 02m
2 stops
DSM10:32 amDes Moines
$475
Find similar

American Airlines flights from Iowa to Panama City

Our best American Airlines deals on Iowa to Panama City flight tickets
American Airlines
Nov 7
DSM5:04 pmDes Moines
19h 45m
2 stops
PTY1:49 pmPanama City Tocumen Intl
Nov 14
PTY2:49 pmPanama City Tocumen Intl
25h 44m
2 stops
DSM3:33 pmDes Moines
$467
Find similar
American Airlines
Nov 7
DSM5:04 pmDes Moines
19h 45m
2 stops
PTY1:49 pmPanama City Tocumen Intl
Nov 14
PTY2:49 pmPanama City Tocumen Intl
23h 42m
2 stops
DSM1:31 pmDes Moines
$468
Find similar
American Airlines
Jan 1
DSM6:00 amDes Moines
30h 53m
1 stop
PTY1:53 pmPanama City Tocumen Intl
Apr 1
PTY1:50 pmPanama City Tocumen Intl
8h 35m
1 stop
DSM10:25 pmDes Moines
$509
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated septiembre 23, 2025.
Use the filters below to find and compare flights from Iowa to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

jue. 11/6

6:50 pm-7:38 pm

2 stops23h 48m

Panama City Tocumen Intl

jue. 11/13

8:55 am-10:20 pm

1 stop14h 25m

$454

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

jue. 11/6

6:50 pm-7:38 pm

2 stops23h 48m

Panama City Tocumen Intl

jue. 11/13

8:55 am-10:20 pm

1 stop14h 25m

$457

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

dom. 10/12

5:47 am-12:56 pm

1 stop7h 09m

Panama City Tocumen Intl

mié. 10/22

2:21 pm-10:30 pm

1 stop8h 09m

$461

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

dom. 10/12

5:47 am-12:56 pm

1 stop7h 09m

Panama City Tocumen Intl

mié. 10/22

2:21 pm-9:20 am

2 stops18h 59m

$466

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

vie. 11/7

5:04 pm-1:49 pm

2 stops19h 45m

Panama City Tocumen Intl

vie. 11/14

2:49 pm-3:33 pm

2 stops25h 44m

$467

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

vie. 11/7

5:04 pm-1:49 pm

2 stops19h 45m

Panama City Tocumen Intl

vie. 11/14

2:49 pm-1:31 pm

2 stops23h 42m

$468

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

sáb. 10/11

5:15 pm-12:56 pm

1 stop19h 41m

Panama City Tocumen Intl

mar. 10/21

2:21 pm-10:30 pm

1 stop8h 09m

$470

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

sáb. 10/11

3:05 pm-6:37 pm

1 stop27h 32m

Panama City Tocumen Intl

lun. 10/20

3:30 pm-10:32 am

2 stops19h 02m

$475

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

dom. 10/12

10:41 am-8:19 pm

1 stop9h 38m

Panama City Tocumen Intl

sáb. 10/18

12:03 pm-9:51 am

1 stop21h 48m

$519

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

dom. 10/12

10:41 am-8:19 pm

1 stop9h 38m

Panama City Tocumen Intl

sáb. 10/18

12:03 pm-9:51 am

1 stop21h 48m

$525

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

See travel insights to Panama City from

How to get the cheapest flight ticket from Iowa to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, December is the cheapest month to fly from Iowa to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $414. If you’re not able to fly to Panama City in December, then September is your next best option. Flight prices from Iowa to Panama City during September average around $441.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Sunday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $412. If your travel schedule is flexible, try to avoid departing on a Tuesday because tickets tend to average around $578. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the afternoon. Flights from Iowa to Panama City during this time can be as low as $439. Try not to purchase tickets in the morning because they tend to be around $539. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Iowa to Panama City flights?

You could potentially save up to 27% on your flight if you consider stops on a Iowa to Panama City flight.

Cheap Iowa to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Panama City

Direct flights

None
There are no direct flights from Iowa to Panama City. There are no popular flight routes from Iowa to Panama City.
Search flight deals

  • When did momondo last update prices for flights from Iowa to Panama City Tocumen Intl Airport?

    Prices for flights from Iowa to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from Iowa to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Iowa to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Iowa to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Iowa to Panama City

Compare and see reviews for airlines that fly from Iowa to Panama City with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $414Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights
DeltaPriceFrom $441Free CancellationRating
7.9
7,974 reviews
Search Delta flights
American AirlinesPriceFrom $445Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Panama City?

Finding the right flight to Panama City from Iowa is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Iowa to Panama City with flexible booking policies on momondo?

Flights from Iowa to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Iowa to Panama City?

Once all potential Iowa to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Iowa to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Iowa are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
jue. 10/23
jue. 10/30
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Panama