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Cheap flights from Iowa to Panama City from $198

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to Panama City departing on 9/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Iowa to Panama City

Cheap round-trip flights

United Airlines Logo
2:58 pm - 2:14 pmDSM-PTY
23h 16m1 stop
United Airlines Logo
10:00 am - 10:28 pmPTY-DSM
12h 28m1 stop
$447United Airlines
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Sat, Sep 20 - Sat, Sep 27
Delta Logo
6:39 pm - 12:56 pmDSM-PTY
18h 17m1 stop
Delta Logo
2:21 pm - 10:43 pmPTY-DSM
8h 22m1 stop
$461Delta
Find Deal
Fri, Oct 10 - Fri, Oct 17
United Airlines Logo
6:15 am - 6:37 pmDSM-PTY
12h 22m1 stop
United Airlines Logo
3:30 pm - 12:19 pmPTY-DSM
20h 49m2 stops
$466United Airlines
Find Deal
Sun, Oct 12 - Sat, Oct 18
Delta Logo
5:14 pm - 12:56 pmDSM-PTY
19h 42m1 stop
Delta Logo
2:21 pm - 10:43 pmPTY-DSM
8h 22m1 stop
$470Delta
Find Deal
Sat, Oct 11 - Thu, Oct 23
Delta Logo
6:20 am - 8:01 pmDSM-PTY
12h 41m2 stops
Delta Logo
3:17 pm - 5:37 pmPTY-DSM
27h 20m1 stop
$475Delta
Find Deal
Sat, Dec 6 - Fri, Dec 19
Delta Logo
6:30 pm - 1:52 pmDSM-PTY
18h 22m1 stop
Delta Logo
8:10 am - 10:27 amPTY-DSM
27h 17m1 stop
$479Delta
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Fri, Dec 5 - Sun, Dec 21
United Airlines Logo
6:50 pm - 8:02 pmDSM-PTY
24h 12m2 stops
United Airlines Logo
8:55 am - 9:40 pmPTY-DSM
13h 45m2 stops
$480United Airlines
Find Deal
Fri, Dec 5 - Fri, Dec 19
American Airlines Logo
2:08 pm - 1:25 pmDSM-PTY
22h 17m2 stops
American Airlines Logo
4:45 pm - 2:34 pmPTY-DSM
22h 49m2 stops
$483American Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 18
American Airlines Logo
5:35 pm - 2:03 pmCID-PTY
20h 28m2 stops
American Airlines Logo
3:15 pm - 2:20 pmPTY-CID
23h 05m2 stops
$546American Airlines
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Sun, Oct 19 - Fri, Oct 24
Logo
6:25 am - 10:25 amOMA-PTY
28h 00m3 stops
Logo
3:20 am - 1:28 pmPTY-OMA
34h 08m3 stops
$1,707
Find Deal
Fri, Sep 19 - Thu, Sep 25

American Airlines flights from Iowa to Panama City

Our best American Airlines deals on Iowa to Panama City flight tickets
American Airlines
Dec 4
DSM2:08 pmDes Moines
22h 17m
2 stops
PTY1:25 pmPanama City Tocumen Intl
Dec 18
PTY4:45 pmPanama City Tocumen Intl
22h 49m
2 stops
DSM2:34 pmDes Moines
$483
Find similar
American Airlines
Oct 19
CID5:35 pmCedar Rapids
20h 28m
2 stops
PTY2:03 pmPanama City Tocumen Intl
Oct 24
PTY3:15 pmPanama City Tocumen Intl
23h 05m
2 stops
CID2:20 pmCedar Rapids
$546
Find similar
American Airlines
Dec 4
CID6:31 pmCedar Rapids
19h 54m
2 stops
PTY3:25 pmPanama City Tocumen Intl
Dec 7
PTY4:15 pmPanama City Tocumen Intl
20h 43m
2 stops
CID11:58 amCedar Rapids
$551
Find similar

Delta flights from Iowa to Panama City

Our best Delta deals on Iowa to Panama City flight tickets
Delta
Oct 10
DSM6:39 pmDes Moines
18h 17m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Oct 17
PTY2:21 pmPanama City Tocumen Intl
8h 22m
1 stop
DSM10:43 pmDes Moines
$461
Find similar
Delta
Oct 11
DSM5:14 pmDes Moines
19h 42m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Oct 23
PTY2:21 pmPanama City Tocumen Intl
8h 22m
1 stop
DSM10:43 pmDes Moines
$470
Find similar
Delta
Dec 6
DSM6:20 amDes Moines
12h 41m
2 stops
PTY8:01 pmPanama City Tocumen Intl
Dec 19
PTY3:17 pmPanama City Tocumen Intl
27h 20m
1 stop
DSM5:37 pmDes Moines
$475
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 7, 2025.
Use the filters below to find and compare flights from Iowa to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 9/20

2:58 pm-2:14 pm

1 stop23h 16m

Panama City Tocumen Intl

Sat 9/27

10:00 am-10:28 pm

1 stop12h 28m

$447

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Fri 10/10

6:39 pm-12:56 pm

1 stop18h 17m

Panama City Tocumen Intl

Fri 10/17

2:21 pm-10:43 pm

1 stop8h 22m

$461

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 10/12

6:15 am-6:37 pm

1 stop12h 22m

Panama City Tocumen Intl

Sat 10/18

3:30 pm-12:19 pm

2 stops20h 49m

$466

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 10/11

5:14 pm-12:56 pm

1 stop19h 42m

Panama City Tocumen Intl

Thu 10/23

2:21 pm-10:43 pm

1 stop8h 22m

$470

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 12/6

6:20 am-8:01 pm

2 stops12h 41m

Panama City Tocumen Intl

Fri 12/19

3:17 pm-5:37 pm

1 stop27h 20m

$475

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Fri 12/5

6:30 pm-1:52 pm

1 stop18h 22m

Panama City Tocumen Intl

Sun 12/21

8:10 am-10:27 am

1 stop27h 17m

$479

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Fri 12/5

6:50 pm-8:02 pm

2 stops24h 12m

Panama City Tocumen Intl

Fri 12/19

8:55 am-9:40 pm

2 stops13h 45m

$480

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Thu 12/4

2:08 pm-1:25 pm

2 stops22h 17m

Panama City Tocumen Intl

Thu 12/18

4:45 pm-2:34 pm

2 stops22h 49m

$483

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Sun 10/19

5:35 pm-2:03 pm

2 stops20h 28m

Panama City Tocumen Intl

Fri 10/24

3:15 pm-2:20 pm

2 stops23h 05m

$546

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

Fri 9/19

6:25 am-10:25 am

3 stops28h 00m

Panama City Tocumen Intl

Thu 9/25

3:20 am-1:28 pm

3 stops34h 08m

$1,707

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Iowa to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from Iowa to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $395. If you’re not able to fly to Panama City in September, then December is your next best option. Flight prices from Iowa to Panama City during December average around $408.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Sunday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $412. If your travel schedule is flexible, try to avoid departing on a Tuesday because tickets tend to average around $578. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the afternoon. Flights from Iowa to Panama City during this time can be as low as $439. Try not to purchase tickets in the morning because they tend to be around $539. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Iowa to Panama City flights?

You could potentially save up to 13% on your flight if you consider stops on a Iowa to Panama City flight.

Cheap Iowa to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Panama City

Best Price Found

$198

Fastest flight time

6h 56m

Direct flights

None

Airports in Panama City

1 airport
The best one-way flight to Panama City from Iowa in the past 72 hours is $198. The best round-trip flight deal from Iowa to Panama City found on momondo in the last 72 hours is $447.
The fastest flight from Iowa to Panama City takes 6h 56m
There are no direct flights from Iowa to Panama City. Popular non-direct routes for this connection are Cedar Rapids Airport - Panama City Tocumen Intl Airport, Des Moines Airport - Panama City Tocumen Intl Airport and Omaha Eppley Airfield Airport - Panama City Tocumen Intl Airport.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
Search flight deals

  • When did momondo last update prices for flights from Iowa to Panama City Tocumen Intl Airport?

    Prices for flights from Iowa to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from Iowa to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Iowa to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Iowa to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Iowa to Panama City

Compare and see reviews for airlines that fly from Iowa to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $349Free CancellationRating
8.0
7,985 reviews
Search Delta flights
United AirlinesPriceFrom $411Free CancellationRating
7.4
8,917 reviews
Search United Airlines flights
American AirlinesPriceFrom $445Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Panama City?

Finding the right flight to Panama City from Iowa is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Iowa to Panama City with flexible booking policies on momondo?

Flights from Iowa to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Iowa to Panama City?

Once all potential Iowa to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Iowa to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Iowa are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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