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Cheap flights from Iowa to Panama City from $299

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to Panama City departing on 6/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Iowa to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
8:25 pm - 4:12 pm
DSM
-
PTY
19h 47m
2 stops
United Airlines Logo
7:55 am - 10:45 pm
PTY
-
DSM
14h 50m
1 stop
$597United Airlines
Sun, May 10 - Thu, May 14
American Airlines Logo
1:48 pm - 12:14 pm
DSM
-
PTY
22h 26m
2 stops
American Airlines Logo
1:14 pm - 9:11 am
PTY
-
DSM
19h 57m
2 stops
$601American Airlines
Thu, May 21 - Thu, May 28
United Airlines Logo
8:15 am - 2:14 pm
DSM
-
PTY
29h 59m
1 stop
United Airlines Logo
7:55 am - 10:45 pm
PTY
-
DSM
14h 50m
1 stop
$603United Airlines
Sun, May 10 - Thu, May 14
American Airlines Logo
8:02 pm - 12:14 pm
DSM
-
PTY
16h 12m
2 stops
American Airlines Logo
1:14 pm - 11:08 pm
PTY
-
DSM
9h 54m
1 stop
$604American Airlines
Mon, May 25 - Mon, Jun 1
Delta Logo
5:45 am - 1:13 pm
DSM
-
PTY
7h 28m
1 stop
Delta Logo
2:28 pm - 10:26 pm
PTY
-
DSM
7h 58m
1 stop
$613Delta
Sun, Aug 16 - Wed, Aug 26
Delta Logo
5:45 am - 1:13 pm
DSM
-
PTY
7h 28m
1 stop
Delta Logo
2:28 pm - 9:19 am
PTY
-
DSM
18h 51m
2 stops
$617Delta
Sun, Aug 16 - Thu, Aug 27
American Airlines Logo
1:37 pm - 12:14 pm
DSM
-
PTY
22h 37m
2 stops
American Airlines Logo
1:14 pm - 6:19 pm
PTY
-
DSM
29h 05m
2 stops
$618American Airlines
Mon, May 25 - Mon, Jun 1
Delta Logo
5:45 am - 1:13 pm
DSM
-
PTY
7h 28m
1 stop
Delta Logo
2:28 pm - 1:22 pm
PTY
-
DSM
22h 54m
1 stop
$623Delta
Sun, Aug 16 - Sat, Aug 29
United Airlines Logo
8:15 am - 2:14 pm
DSM
-
PTY
29h 59m
1 stop
United Airlines Logo
7:55 am - 10:45 pm
PTY
-
DSM
14h 50m
1 stop
$624United Airlines
Sun, May 10 - Thu, May 14
Multiple Airlines Logo
12:37 pm - 7:39 am
CID
-
PTY
19h 02m
1 stop
Multiple Airlines Logo
6:32 pm - 8:27 am
PTY
-
CID
13h 55m
1 stop
$1,035Multiple Airlines
Tue, Jun 9 - Wed, Jun 10

United Airlines flights from Iowa to Panama City

Our best United Airlines deals on Iowa to Panama City flight tickets
United Airlines
Apr 11
DSM8:04 amDes Moines
10h 33m
2 stops
PTY6:37 pmPanama City Tocumen Intl
Apr 15
PTY3:30 pmPanama City Tocumen Intl
20h 59m
2 stops
DSM12:29 pmDes Moines
$597
United Airlines
Apr 11
DSM8:20 amDes Moines
10h 17m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Apr 16
PTY7:55 amPanama City Tocumen Intl
14h 48m
1 stop
DSM10:43 pmDes Moines
$613
United Airlines
Apr 22
DSM8:20 amDes Moines
10h 17m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Apr 26
PTY3:30 pmPanama City Tocumen Intl
20h 59m
2 stops
DSM12:29 pmDes Moines
$617

American Airlines flights from Iowa to Panama City

Our best American Airlines deals on Iowa to Panama City flight tickets
American Airlines
May 21
DSM1:48 pmDes Moines
22h 26m
2 stops
PTY12:14 pmPanama City Tocumen Intl
May 28
PTY1:14 pmPanama City Tocumen Intl
19h 57m
2 stops
DSM9:11 amDes Moines
$601
American Airlines
May 25
DSM8:02 pmDes Moines
16h 12m
2 stops
PTY12:14 pmPanama City Tocumen Intl
Jun 1
PTY1:14 pmPanama City Tocumen Intl
9h 54m
1 stop
DSM11:08 pmDes Moines
$604
American Airlines
May 25
DSM1:37 pmDes Moines
22h 37m
2 stops
PTY12:14 pmPanama City Tocumen Intl
Jun 1
PTY1:14 pmPanama City Tocumen Intl
29h 05m
2 stops
DSM6:19 pmDes Moines
$618

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 11, 2026.
Use the filters below to find and compare flights from Iowa to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 5/10

8:25 pm-4:12 pm

2 stops19h 47m

Panama City Tocumen Intl

Thu 5/14

7:55 am-10:45 pm

1 stop14h 50m

$597

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Thu 5/21

1:48 pm-12:14 pm

2 stops22h 26m

Panama City Tocumen Intl

Thu 5/28

1:14 pm-9:11 am

2 stops19h 57m

$601

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 5/10

8:15 am-2:14 pm

1 stop29h 59m

Panama City Tocumen Intl

Thu 5/14

7:55 am-10:45 pm

1 stop14h 50m

$603

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Mon 5/25

8:02 pm-12:14 pm

2 stops16h 12m

Panama City Tocumen Intl

Mon 6/1

1:14 pm-11:08 pm

1 stop9h 54m

$604
Quickest round-trip

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 8/16

5:45 am-1:13 pm

1 stop7h 28m

Panama City Tocumen Intl

Wed 8/26

2:28 pm-10:26 pm

1 stop7h 58m

$613

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 8/16

5:45 am-1:13 pm

1 stop7h 28m

Panama City Tocumen Intl

Thu 8/27

2:28 pm-9:19 am

2 stops18h 51m

$617

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Mon 5/25

1:37 pm-12:14 pm

2 stops22h 37m

Panama City Tocumen Intl

Mon 6/1

1:14 pm-6:19 pm

2 stops29h 05m

$618

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 8/16

5:45 am-1:13 pm

1 stop7h 28m

Panama City Tocumen Intl

Sat 8/29

2:28 pm-1:22 pm

1 stop22h 54m

$623

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 5/10

8:15 am-2:14 pm

1 stop29h 59m

Panama City Tocumen Intl

Thu 5/14

7:55 am-10:45 pm

1 stop14h 50m

$624

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Tue 6/9

12:37 pm-7:39 am

1 stop19h 02m

Panama City Tocumen Intl

Wed 6/10

6:32 pm-8:27 am

1 stop13h 55m

$1,035

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Iowa to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, February is the cheapest month to fly from Iowa to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $461. If you’re not able to fly to Panama City in February, then September is your next best option. Flight prices from Iowa to Panama City during September average around $488.

Can stopping save me money on Iowa to Panama City flights?

You could potentially save up to 13% on your flight if you consider stops on a Iowa to Panama City flight.

Cheap Iowa to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Panama City

Fastest flight time

7h 23m

Direct flights

None
The fastest flight from Iowa to Panama City takes 7h 23m
There are no direct flights from Iowa to Panama City. There are no popular flight routes from Iowa to Panama City.
Search flight deals

Frequently asked questions about flying from Iowa to Panama City

  • When did momondo last update prices for flights from Iowa to Panama City Tocumen Intl Airport?

    Prices for flights from Iowa to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from Iowa to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Iowa to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Iowa to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Iowa to Panama City

Compare and see reviews for airlines that fly from Iowa to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $441Free CancellationRating
7.9
8,406 reviews
Search Delta flights
United AirlinesPriceFrom $461Free CancellationRating
7.4
9,569 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Panama City?

Finding the right flight to Panama City from Iowa is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Iowa to Panama City with flexible booking policies on momondo?

Flights from Iowa to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Iowa to Panama City?

Once all potential Iowa to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Iowa to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Iowa are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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