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Cheap flights from Iowa to Panama City from $288

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to Panama City departing on 11/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Iowa to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
8:15 am - 5:07 pmDSM-PTY
7h 52m1 stop
United Airlines Logo
8:55 am - 10:30 pmPTY-DSM
14h 35m1 stop
$462United Airlines
Find Deal
Sat, Dec 13 - Fri, Dec 26
United Airlines Logo
8:00 am - 7:38 pmDSM-PTY
10h 38m2 stops
United Airlines Logo
4:41 pm - 9:45 amPTY-DSM
18h 04m2 stops
$466United Airlines
Find Deal
Thu, Feb 26 - Sat, Mar 7
United Airlines Logo
6:05 am - 2:45 pmDSM-PTY
7h 40m1 stop
United Airlines Logo
4:41 pm - 10:20 pmPTY-DSM
30h 39m1 stop
$471United Airlines
Find Deal
Mon, Nov 24 - Thu, Nov 27
American Airlines Logo
5:04 pm - 1:43 pmDSM-PTY
19h 39m2 stops
American Airlines Logo
2:43 pm - 10:40 amPTY-DSM
20h 57m2 stops
$516American Airlines
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Mon, Nov 24 - Thu, Nov 27
Delta Logo
4:15 pm - 12:55 pmCID-PTY
20h 40m2 stops
Delta Logo
2:20 pm - 11:27 amPTY-CID
21h 07m2 stops
$546Delta
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Sat, May 2 - Wed, May 6
Delta Logo
5:35 am - 1:55 pmCID-PTY
7h 20m1 stop
Delta Logo
3:20 pm - 3:35 pmPTY-CID
25h 15m2 stops
$589Delta
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Mon, Jan 12 - Wed, Jan 21
American Airlines Logo
7:57 pm - 1:43 pmCID-PTY
16h 46m2 stops
American Airlines Logo
2:43 pm - 5:22 pmPTY-CID
27h 39m2 stops
$626American Airlines
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Fri, Nov 28 - Tue, Dec 2
Multiple Airlines Logo
6:44 pm - 8:19 pmCID-PTY
24h 35m1 stop
Multiple Airlines Logo
2:55 am - 8:25 amPTY-CID
30h 30m2 stops
$897Multiple Airlines
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Fri, Dec 19 - Wed, Jan 14
Multiple Airlines Logo
6:44 pm - 8:19 pmCID-PTY
24h 35m1 stop
Multiple Airlines Logo
2:55 am - 8:25 amPTY-CID
30h 30m2 stops
$905Multiple Airlines
Find Deal
Fri, Dec 19 - Wed, Jan 14
British Airways Logo
3:28 pm - 1:53 pmDSM-PTY
21h 25m2 stops
British Airways Logo
4:55 pm - 10:47 amPTY-DSM
18h 52m2 stops
$999British Airways
Find Deal
Wed, Dec 24 - Wed, Dec 31

United Airlines flights from Iowa to Panama City

Our best United Airlines deals on Iowa to Panama City flight tickets
United Airlines
Dec 13
DSM8:15 amDes Moines
7h 52m
1 stop
PTY5:07 pmPanama City Tocumen Intl
Dec 26
PTY8:55 amPanama City Tocumen Intl
14h 35m
1 stop
DSM10:30 pmDes Moines
$462
Find similar
United Airlines
Feb 26
DSM8:08 amDes Moines
10h 30m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Mar 7
PTY4:41 pmPanama City Tocumen Intl
18h 04m
2 stops
DSM9:45 amDes Moines
$466
Find similar
United Airlines
Nov 24
DSM6:05 amDes Moines
7h 40m
1 stop
PTY2:45 pmPanama City Tocumen Intl
Nov 27
PTY4:41 pmPanama City Tocumen Intl
30h 39m
1 stop
DSM10:20 pmDes Moines
$471
Find similar

American Airlines flights from Iowa to Panama City

Our best American Airlines deals on Iowa to Panama City flight tickets
American Airlines
Nov 24
DSM5:04 pmDes Moines
19h 39m
2 stops
PTY1:43 pmPanama City Tocumen Intl
Nov 27
PTY2:43 pmPanama City Tocumen Intl
20h 57m
2 stops
DSM10:40 amDes Moines
$516
Find similar
American Airlines
Nov 28
CID7:57 pmCedar Rapids
16h 46m
2 stops
PTY1:43 pmPanama City Tocumen Intl
Dec 2
PTY2:43 pmPanama City Tocumen Intl
27h 39m
2 stops
CID5:22 pmCedar Rapids
$626
Find similar
American Airlines
Jan 12
CID5:44 pmCedar Rapids
18h 43m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Jan 23
PTY2:27 pmPanama City Tocumen Intl
20h 02m
2 stops
CID9:29 amCedar Rapids
$636
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 9, 2025.
Use the filters below to find and compare flights from Iowa to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 12/13

8:15 am-5:07 pm

1 stop7h 52m

Panama City Tocumen Intl

Fri 12/26

8:55 am-10:30 pm

1 stop14h 35m

$462

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Thu 2/26

8:00 am-7:38 pm

2 stops10h 38m

Panama City Tocumen Intl

Sat 3/7

4:41 pm-9:45 am

2 stops18h 04m

$466

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Mon 11/24

6:05 am-2:45 pm

1 stop7h 40m

Panama City Tocumen Intl

Thu 11/27

4:41 pm-10:20 pm

1 stop30h 39m

$471

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Mon 11/24

5:04 pm-1:43 pm

2 stops19h 39m

Panama City Tocumen Intl

Thu 11/27

2:43 pm-10:40 am

2 stops20h 57m

$516

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Sat 5/2

4:15 pm-12:55 pm

2 stops20h 40m

Panama City Tocumen Intl

Wed 5/6

2:20 pm-11:27 am

2 stops21h 07m

$546

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Mon 1/12

5:35 am-1:55 pm

1 stop7h 20m

Panama City Tocumen Intl

Wed 1/21

3:20 pm-3:35 pm

2 stops25h 15m

$589

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Fri 11/28

7:57 pm-1:43 pm

2 stops16h 46m

Panama City Tocumen Intl

Tue 12/2

2:43 pm-5:22 pm

2 stops27h 39m

$626

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Fri 12/19

6:44 pm-8:19 pm

1 stop24h 35m

Panama City Tocumen Intl

Wed 1/14

2:55 am-8:25 am

2 stops30h 30m

$897

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Fri 12/19

6:44 pm-8:19 pm

1 stop24h 35m

Panama City Tocumen Intl

Wed 1/14

2:55 am-8:25 am

2 stops30h 30m

$905

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Wed 12/24

3:28 pm-1:53 pm

2 stops21h 25m

Panama City Tocumen Intl

Wed 12/31

4:55 pm-10:47 am

2 stops18h 52m

$999

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Iowa to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from Iowa to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $441. If you’re not able to fly to Panama City in September, then July is your next best option. Flight prices from Iowa to Panama City during July average around $455.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Sunday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $412. If your travel schedule is flexible, try to avoid departing on a Tuesday because tickets tend to average around $578. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the afternoon. Flights from Iowa to Panama City during this time can be as low as $439. Try not to purchase tickets in the morning because they tend to be around $539. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Iowa to Panama City flights?

You could potentially save up to 13% on your flight if you consider stops on a Iowa to Panama City flight.

Cheap Iowa to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Panama City

Direct flights

None
There are no direct flights from Iowa to Panama City. There are no popular flight routes from Iowa to Panama City.
Search flight deals

  • When did momondo last update prices for flights from Iowa to Panama City Tocumen Intl Airport?

    Prices for flights from Iowa to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from Iowa to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Iowa to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Iowa to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Iowa to Panama City

Compare and see reviews for airlines that fly from Iowa to Panama City with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $414Free CancellationRating
7.4
9,012 reviews
Search United Airlines flights
DeltaPriceFrom $441Free CancellationRating
7.9
8,004 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Panama City?

Finding the right flight to Panama City from Iowa is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Iowa to Panama City with flexible booking policies on momondo?

Flights from Iowa to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Iowa to Panama City?

Once all potential Iowa to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Iowa to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Iowa are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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