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Cheap flights from Guayaquil to Medellín from $150

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Guayaquil to Medellín departing on 12/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
1:25 pm - 3:10 pm
GYE
-
MDE
1h 45mnonstop
Avianca Logo
5:05 pm - 11:35 pm
MDE
-
GYE
6h 30m2 stops
$283Avianca
Mon, Jan 12 - Wed, Jan 14
Copa Airlines Logo
6:34 pm - 8:18 am
GYE
-
MDE
13h 44m1 stop
Copa Airlines Logo
10:46 am - 5:36 pm
MDE
-
GYE
6h 50m1 stop
$288Copa Airlines
Fri, Dec 26 - Mon, Dec 29
Copa Airlines Logo
6:28 pm - 8:14 am
GYE
-
MDE
13h 46m1 stop
Copa Airlines Logo
8:35 am - 1:33 pm
MDE
-
GYE
4h 58m1 stop
$290Copa Airlines
Fri, May 15 - Mon, May 25
Copa Airlines Logo
6:28 pm - 8:14 am
GYE
-
MDE
13h 46m1 stop
Copa Airlines Logo
10:35 am - 8:53 pm
MDE
-
GYE
10h 18m1 stop
$295Copa Airlines
Fri, Apr 10 - Wed, Apr 15
Avianca Logo
1:25 pm - 3:10 pm
GYE
-
MDE
1h 45mnonstop
Avianca Logo
6:25 pm - 8:25 pm
MDE
-
GYE
2h 00mnonstop
$296Avianca
Mon, Jan 12 - Wed, Jan 14
Copa Airlines Logo
8:32 am - 2:45 pm
GYE
-
MDE
6h 13m1 stop
Copa Airlines Logo
12:42 pm - 11:41 pm
MDE
-
GYE
10h 59m1 stop
$300Copa Airlines
Mon, Mar 2 - Fri, Mar 6
Avianca Logo
1:35 pm - 3:15 pm
GYE
-
MDE
1h 40mnonstop
Avianca Logo
4:44 pm - 11:20 pm
MDE
-
GYE
6h 36m2 stops
$301Avianca
Wed, Apr 22 - Sat, Apr 25
Avianca Logo
4:40 am - 9:05 am
GYE
-
MDE
4h 25m1 stop
Avianca Logo
6:25 pm - 8:25 pm
MDE
-
GYE
2h 00mnonstop
$302Avianca
Sun, Jan 11 - Wed, Jan 14
Copa Airlines Logo
6:28 pm - 8:14 am
GYE
-
MDE
13h 46m1 stop
Copa Airlines Logo
6:20 pm - 12:01 am
MDE
-
GYE
5h 41m1 stop
$303Copa Airlines
Fri, May 15 - Fri, May 22
Avianca Logo
9:05 am - 12:55 pm
GYE
-
MDE
3h 50m1 stop
Avianca Logo
6:45 pm - 11:35 pm
MDE
-
GYE
4h 50m1 stop
$308Avianca
Thu, Dec 25 - Tue, Dec 30

Avianca flights from Guayaquil to Medellín Jose Maria Cordova Intl Airport

Our best Avianca deals on Guayaquil to Medellín Jose Maria Cordova Intl Airport flight tickets
Avianca
Jan 12
GYE1:25 pmGuayaquil Jose Joaquin de Olmedo
1h 45m
MDE3:10 pmMedellín Jose Maria Cordova Intl
Jan 14
MDE5:05 pmMedellín Jose Maria Cordova Intl
6h 30m
2 stops
GYE11:35 pmGuayaquil Jose Joaquin de Olmedo
$283
Find similar
Avianca
Jan 12
GYE1:25 pmGuayaquil Jose Joaquin de Olmedo
1h 45m
MDE3:10 pmMedellín Jose Maria Cordova Intl
Jan 14
MDE6:25 pmMedellín Jose Maria Cordova Intl
2h 00m
GYE8:25 pmGuayaquil Jose Joaquin de Olmedo
$296
Find similar
Avianca
Apr 22
GYE1:35 pmGuayaquil Jose Joaquin de Olmedo
1h 40m
MDE3:15 pmMedellín Jose Maria Cordova Intl
Apr 25
MDE4:44 pmMedellín Jose Maria Cordova Intl
6h 36m
2 stops
GYE11:20 pmGuayaquil Jose Joaquin de Olmedo
$301
Find similar

Copa Airlines flights from Guayaquil to Medellín Jose Maria Cordova Intl Airport

Our best Copa Airlines deals on Guayaquil to Medellín Jose Maria Cordova Intl Airport flight tickets
Copa Airlines
Dec 26
GYE12:20 pmGuayaquil Jose Joaquin de Olmedo
7h 56m
1 stop
MDE8:16 pmMedellín Jose Maria Cordova Intl
Dec 30
MDE5:00 amMedellín Jose Maria Cordova Intl
8h 34m
1 stop
GYE1:34 pmGuayaquil Jose Joaquin de Olmedo
$288
Find similar
Copa Airlines
May 5
GYE6:28 pmGuayaquil Jose Joaquin de Olmedo
13h 46m
1 stop
MDE8:14 amMedellín Jose Maria Cordova Intl
May 25
MDE8:35 amMedellín Jose Maria Cordova Intl
4h 58m
1 stop
GYE1:33 pmGuayaquil Jose Joaquin de Olmedo
$290
Find similar
Copa Airlines
Apr 10
GYE6:28 pmGuayaquil Jose Joaquin de Olmedo
13h 46m
1 stop
MDE8:14 amMedellín Jose Maria Cordova Intl
Apr 15
MDE10:35 amMedellín Jose Maria Cordova Intl
10h 18m
1 stop
GYE8:53 pmGuayaquil Jose Joaquin de Olmedo
$295
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Guayaquil to Medellín Jose Maria Cordova Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Guayaquil to Medellín Jose Maria Cordova Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Mon 1/12

1:25 pm-3:10 pm

Nonstop1h 45m

Medellín Jose Maria Cordova Intl

Wed 1/14

5:05 pm-11:35 pm

2 stops6h 30m

$283

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Fri 12/26

6:34 pm-8:18 am

1 stop13h 44m

Medellín Jose Maria Cordova Intl

Mon 12/29

10:46 am-5:36 pm

1 stop6h 50m

$288

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Fri 5/15

6:28 pm-8:14 am

1 stop13h 46m

Medellín Jose Maria Cordova Intl

Mon 5/25

8:35 am-1:33 pm

1 stop4h 58m

$290

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Fri 4/10

6:28 pm-8:14 am

1 stop13h 46m

Medellín Jose Maria Cordova Intl

Wed 4/15

10:35 am-8:53 pm

1 stop10h 18m

$295

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Mon 1/12

1:25 pm-3:10 pm

Nonstop1h 45m

Medellín Jose Maria Cordova Intl

Wed 1/14

6:25 pm-8:25 pm

Nonstop2h 00m

$296

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Mon 3/2

8:32 am-2:45 pm

1 stop6h 13m

Medellín Jose Maria Cordova Intl

Fri 3/6

12:42 pm-11:41 pm

1 stop10h 59m

$300

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Wed 4/22

1:35 pm-3:15 pm

Nonstop1h 40m

Medellín Jose Maria Cordova Intl

Sat 4/25

4:44 pm-11:20 pm

2 stops6h 36m

$301

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Sun 1/11

4:40 am-9:05 am

1 stop4h 25m

Medellín Jose Maria Cordova Intl

Wed 1/14

6:25 pm-8:25 pm

Nonstop2h 00m

$302

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Fri 5/15

6:28 pm-8:14 am

1 stop13h 46m

Medellín Jose Maria Cordova Intl

Fri 5/22

6:20 pm-12:01 am

1 stop5h 41m

$303

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Thu 12/25

9:05 am-12:55 pm

1 stop3h 50m

Medellín Jose Maria Cordova Intl

Tue 12/30

6:45 pm-11:35 pm

1 stop4h 50m

$308

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Medellín from

How to get the cheapest flight ticket from Guayaquil to Medellín Jose Maria Cordova Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Medellín Jose Maria Cordova Intl Airport?

In general, May is the cheapest month to fly from Guayaquil to Medellín Jose Maria Cordova Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $248. If you aren’t able to travel during the month of May, then book flights to Medellín Jose Maria Cordova Intl Airport from Guayaquil during June instead. Flights to Medellín Jose Maria Cordova Intl Airport in June, while not as cheap as those in May, still average around $249.

What is the cheapest day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

The cheapest day to depart from Guayaquil to Medellín Jose Maria Cordova Intl Airport is on a Saturday. Travelers who choose to depart for Medellín Jose Maria Cordova Intl Airport on a Saturday will often find tickets for as low as $231. On the other hand, Friday is the most expensive day to depart from Guayaquil because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $423.

What is the cheapest time of day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

Our data shows that the cheapest Guayaquil to Medellín Jose Maria Cordova Intl Airport flights are usually those with departure times in the morning. Our users have found flights to Medellín Jose Maria Cordova Intl Airport in the morning for as low as $242. In contrast, the most expensive time of day to depart to Medellín Jose Maria Cordova Intl Airport is at noon when prices are around $329.

What is the cheapest Guayaquil Jose Joaquin de Olmedo to Medellín Jose Maria Cordova Intl flight route?

Fly from Guayaquil Jose Joaquin de Olmedo to Medellín Jose Maria Cordova Intl for the best Guayaquil Jose Joaquin de Olmedo - Medellín Jose Maria Cordova Intl flight prices

How far in advance should I book a flight to Medellín Jose Maria Cordova Intl Airport?

You are more likely to see cheaper flights to Medellín Jose Maria Cordova Intl Airport from Guayaquil when booking weeks ahead of your departure date. In general, you can expect to find flights to Medellín Jose Maria Cordova Intl Airport for around $278 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Medellín Jose Maria Cordova Intl Airport from Guayaquil for as low as $252 on momondo.

What cabin class options are available on Guayaquil Jose Joaquin de Olmedo to Medellín Jose Maria Cordova Intl flights?

There is only 1 cabin class available to choose from on Guayaquil Jose Joaquin de Olmedo to Medellín Jose Maria Cordova Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Guayaquil to Medellín Jose Maria Cordova Intl Airport flights?

You could potentially save up to 24% on your flight if you consider stops on a Guayaquil to Medellín Jose Maria Cordova Intl Airport flight.

How have Guayaquil to Medellín Jose Maria Cordova Intl Airport flight prices changed over time?

As of December 2025, prices for Guayaquil to Medellín Jose Maria Cordova Intl Airport flights are approximately 33% more expensive when compared to flights at the same time last year.

When to book flights from Guayaquil to Medellín Jose Maria Cordova Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Guayaquil to Medellín Jose Maria Cordova Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Guayaquil to Medellín Jose Maria Cordova Intl Airport (GYE to MDE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Guayaquil to Medellín Jose Maria Cordova Intl Airport

Best Price Found

$314

Fastest flight time

1h 45m

Direct flights

Tue, Thu and Sat
The best flight deal from Guayaquil to Medellín Jose Maria Cordova Intl Airport found on momondo in the last 72 hours is $314
The fastest flight from Guayaquil to Medellín Jose Maria Cordova Intl Airport takes 1h 45m
Direct flights go from Guayaquil to Medellín Jose Maria Cordova Intl Airport on Tuesday, Thursday and Saturday. There are no airlines offering direct flights.
Search flight deals

  • How far is Guayaquil Jose Joaquin de Olmedo to Medellín Jose Maria Cordova Intl by plane?

    A flight from Guayaquil Jose Joaquin de Olmedo to Medellín Jose Maria Cordova Intl will travel around 654.1 mi. A reasonable flight in good conditions will take 1h 45m.

  • When did momondo last update prices for flights from Guayaquil Jose Joaquin de Olmedo Airport to Medellín Jose Maria Cordova Intl Airport?

    Prices for flights from Guayaquil Jose Joaquin de Olmedo Airport to Medellín Jose Maria Cordova Intl Airport are updated daily.

  • How many operators does momondo search for flights from Guayaquil Jose Joaquin de Olmedo Airport to Medellín Jose Maria Cordova Intl Airport?

  • How old do you have to be to fly from Guayaquil Jose Joaquin de Olmedo Airport to Medellín Jose Maria Cordova Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Guayaquil Jose Joaquin de Olmedo Airport to Medellín Jose Maria Cordova Intl Airport.

  • What documentation or ID do you need to fly to Medellín Jose Maria Cordova Intl Airport?

    The necessary travel and health documents for your Medellín Jose Maria Cordova Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Guayaquil to Medellín Jose Maria Cordova Intl Airport?

  • What is the most popular airline from Guayaquil to Medellín Jose Maria Cordova Intl Airport?

Best airlines flying from Guayaquil to Medellín Jose Maria Cordova Intl Airport

Compare and see reviews for airlines that fly from Guayaquil to Medellín Jose Maria Cordova Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $218Free CancellationRating
7.6
1,557 reviews
Search Copa Airlines flights
AviancaPriceFrom $225Free CancellationRating
6.6
2,485 reviews
Search Avianca flights

  • Avianca Flights From Guayaquil to Medellín Jose Maria Cordova Intl Airport

    Across 1 Avianca flight from Guayaquil to Medellín Jose Maria Cordova Intl Airport this week, the average price was $292, with the best Avianca deals starting from $225 round-trip. 2,485 users have rated Avianca on momondo, with an average score of 6.6/10.

Traveling to a place near Medellín?

Book flights to Medellín if you plan to visit one of these locations
Guatapé
Rionegro

Why use momondo?

Why should I use momondo to find a flight deal from Guayaquil to Medellín?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Guayaquil to Medellín. momondo saves you time and could save you money on your trip.

Can I find flights from Guayaquil to Medellín with flexible booking policies on momondo?

Yes. All flights to Medellín from Guayaquil on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Guayaquil to Medellín?

Once all potential Guayaquil to Medellín flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Guayaquil to Medellín right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Guayaquil to Medellín now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Medellín and let you know when they change.

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