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Cheap flights from Guayaquil to Medellín from $150

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Guayaquil to Medellín departing on 9/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Guayaquil to Medellín

Cheap round-trip flights

Copa Airlines Logo
8:34 am - 2:45 pmGYE-MDE
6h 11m1 stop
Copa Airlines Logo
4:30 pm - 8:46 pmMDE-GYE
4h 16m1 stop
$268Copa Airlines
Find Deal
Sat, Jan 10 - Thu, Jan 15
Avianca Logo
9:05 am - 3:25 pmGYE-MDE
6h 20m2 stops
Avianca Logo
4:30 pm - 6:30 pmMDE-GYE
2h 00mnonstop
$271Avianca
Find Deal
Tue, Nov 25 - Fri, Nov 28
Avianca Logo
1:45 pm - 3:35 pmGYE-MDE
1h 50mnonstop
Avianca Logo
4:30 pm - 6:30 pmMDE-GYE
2h 00mnonstop
$272Avianca
Find Deal
Fri, Nov 7 - Mon, Nov 10
Avianca Logo
4:00 pm - 5:40 pmGYE-MDE
1h 40mnonstop
Avianca Logo
4:44 pm - 11:20 pmMDE-GYE
6h 36m2 stops
$277Avianca
Find Deal
Mon, Oct 6 - Wed, Oct 8
Avianca Logo
1:45 pm - 3:35 pmGYE-MDE
1h 50mnonstop
Avianca Logo
12:55 pm - 5:45 pmMDE-GYE
4h 50m1 stop
$278Avianca
Find Deal
Fri, Nov 7 - Mon, Nov 10
Avianca Logo
4:00 pm - 5:40 pmGYE-MDE
1h 40mnonstop
Avianca Logo
6:35 pm - 8:25 pmMDE-GYE
1h 50mnonstop
$282Avianca
Find Deal
Mon, Oct 6 - Wed, Oct 8
Avianca Logo
4:40 am - 9:05 amGYE-MDE
4h 25m1 stop
Avianca Logo
7:00 pm - 11:35 pmMDE-GYE
4h 35m1 stop
$284Avianca
Find Deal
Mon, Nov 24 - Fri, Nov 28
Copa Airlines Logo
8:30 am - 8:14 pmGYE-MDE
11h 44m1 stop
Copa Airlines Logo
6:18 pm - 11:37 pmMDE-GYE
5h 19m1 stop
$288Copa Airlines
Find Deal
Tue, Oct 7 - Tue, Oct 14
LATAM Airlines Logo
7:45 am - 11:25 pmGYE-MDE
15h 40m2 stops
LATAM Airlines Logo
5:01 am - 4:50 pmMDE-GYE
11h 49m2 stops
$353LATAM Airlines
Find Deal
Sun, Sep 28 - Wed, Oct 1
LATAM Airlines Logo
4:34 pm - 5:00 amGYE-MDE
12h 26m2 stops
LATAM Airlines Logo
6:25 pm - 6:55 amMDE-GYE
12h 30m2 stops
$370LATAM Airlines
Find Deal
Tue, Oct 14 - Tue, Oct 21

LATAM Airlines flights from Guayaquil to Medellín Jose Maria Cordova Intl Airport

Our best LATAM Airlines deals on Guayaquil to Medellín Jose Maria Cordova Intl Airport flight tickets
LATAM Airlines
Sep 28
GYE7:45 amGuayaquil Jose Joaquin de Olmedo
15h 40m
2 stops
MDE11:25 pmMedellín Jose Maria Cordova Intl
Oct 1
MDE5:01 amMedellín Jose Maria Cordova Intl
11h 49m
2 stops
GYE4:50 pmGuayaquil Jose Joaquin de Olmedo
$353
Find similar
LATAM Airlines
Oct 14
GYE4:34 pmGuayaquil Jose Joaquin de Olmedo
12h 26m
2 stops
MDE5:00 amMedellín Jose Maria Cordova Intl
Oct 21
MDE6:25 pmMedellín Jose Maria Cordova Intl
12h 30m
2 stops
GYE6:55 amGuayaquil Jose Joaquin de Olmedo
$370
Find similar
LATAM Airlines
Oct 3
GYE11:01 pmGuayaquil Jose Joaquin de Olmedo
13h 04m
2 stops
MDE12:05 pmMedellín Jose Maria Cordova Intl
Oct 13
MDE5:22 amMedellín Jose Maria Cordova Intl
12h 01m
2 stops
GYE5:23 pmGuayaquil Jose Joaquin de Olmedo
$383
Find similar

Avianca flights from Guayaquil to Medellín Jose Maria Cordova Intl Airport

Our best Avianca deals on Guayaquil to Medellín Jose Maria Cordova Intl Airport flight tickets
Avianca
Nov 25
GYE9:05 amGuayaquil Jose Joaquin de Olmedo
6h 20m
2 stops
MDE3:25 pmMedellín Jose Maria Cordova Intl
Nov 28
MDE4:30 pmMedellín Jose Maria Cordova Intl
2h 00m
GYE6:30 pmGuayaquil Jose Joaquin de Olmedo
$271
Find similar
Avianca
Nov 7
GYE1:45 pmGuayaquil Jose Joaquin de Olmedo
1h 50m
MDE3:35 pmMedellín Jose Maria Cordova Intl
Nov 10
MDE4:30 pmMedellín Jose Maria Cordova Intl
2h 00m
GYE6:30 pmGuayaquil Jose Joaquin de Olmedo
$272
Find similar
Avianca
Oct 6
GYE4:00 pmGuayaquil Jose Joaquin de Olmedo
1h 40m
MDE5:40 pmMedellín Jose Maria Cordova Intl
Oct 8
MDE4:44 pmMedellín Jose Maria Cordova Intl
6h 36m
2 stops
GYE11:20 pmGuayaquil Jose Joaquin de Olmedo
$277
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Guayaquil to Medellín Jose Maria Cordova Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Guayaquil to Medellín Jose Maria Cordova Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Sat 1/10

8:34 am-2:45 pm

1 stop6h 11m

Medellín Jose Maria Cordova Intl

Thu 1/15

4:30 pm-8:46 pm

1 stop4h 16m

$268

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Tue 11/25

9:05 am-3:25 pm

2 stops6h 20m

Medellín Jose Maria Cordova Intl

Fri 11/28

4:30 pm-6:30 pm

Nonstop2h 00m

$271

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Fri 11/7

1:45 pm-3:35 pm

Nonstop1h 50m

Medellín Jose Maria Cordova Intl

Mon 11/10

4:30 pm-6:30 pm

Nonstop2h 00m

$272

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Mon 10/6

4:00 pm-5:40 pm

Nonstop1h 40m

Medellín Jose Maria Cordova Intl

Wed 10/8

4:44 pm-11:20 pm

2 stops6h 36m

$277

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Fri 11/7

1:45 pm-3:35 pm

Nonstop1h 50m

Medellín Jose Maria Cordova Intl

Mon 11/10

12:55 pm-5:45 pm

1 stop4h 50m

$278

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Mon 10/6

4:00 pm-5:40 pm

Nonstop1h 40m

Medellín Jose Maria Cordova Intl

Wed 10/8

6:35 pm-8:25 pm

Nonstop1h 50m

$282

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Mon 11/24

4:40 am-9:05 am

1 stop4h 25m

Medellín Jose Maria Cordova Intl

Fri 11/28

7:00 pm-11:35 pm

1 stop4h 35m

$284

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Tue 10/7

8:30 am-8:14 pm

1 stop11h 44m

Medellín Jose Maria Cordova Intl

Tue 10/14

6:18 pm-11:37 pm

1 stop5h 19m

$288

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Sun 9/28

7:45 am-11:25 pm

2 stops15h 40m

Medellín Jose Maria Cordova Intl

Wed 10/1

5:01 am-4:50 pm

2 stops11h 49m

$353

GuayaquilMedellín

GYE - MDE

GYEMDE

Guayaquil Jose Joaquin de Olmedo

Tue 10/14

4:34 pm-5:00 am

2 stops12h 26m

Medellín Jose Maria Cordova Intl

Tue 10/21

6:25 pm-6:55 am

2 stops12h 30m

$370

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Medellín from

How to get the cheapest flight ticket from Guayaquil to Medellín Jose Maria Cordova Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Guayaquil and Medellín Jose Maria Cordova Intl Airport?

What is the cheapest month to fly to Medellín Jose Maria Cordova Intl Airport?

In general, May is the cheapest month to fly from Guayaquil to Medellín Jose Maria Cordova Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $247. If you aren’t able to travel during the month of May, then book flights to Medellín Jose Maria Cordova Intl Airport from Guayaquil during April instead. Flights to Medellín Jose Maria Cordova Intl Airport in April, while not as cheap as those in May, still average around $249.

What is the cheapest day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

The cheapest day to depart from Guayaquil to Medellín Jose Maria Cordova Intl Airport is on a Saturday. Travelers who choose to depart for Medellín Jose Maria Cordova Intl Airport on a Saturday will often find tickets for as low as $231. On the other hand, Friday is the most expensive day to depart from Guayaquil because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $401.

What is the cheapest time of day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

Our data shows that the cheapest Guayaquil to Medellín Jose Maria Cordova Intl Airport flights are usually those with departure times in the morning. Our users have found flights to Medellín Jose Maria Cordova Intl Airport in the morning for as low as $242. In contrast, the most expensive time of day to depart to Medellín Jose Maria Cordova Intl Airport is at noon when prices are around $315.

What is the cheapest Guayaquil Jose Joaquin de Olmedo to Medellín Jose Maria Cordova Intl flight route?

Fly from Guayaquil Jose Joaquin de Olmedo to Medellín Jose Maria Cordova Intl for the best Guayaquil Jose Joaquin de Olmedo - Medellín Jose Maria Cordova Intl flight prices

How far in advance should I book a flight to Medellín Jose Maria Cordova Intl Airport?

You are more likely to see cheaper flights to Medellín Jose Maria Cordova Intl Airport from Guayaquil when booking weeks ahead of your departure date. In general, you can expect to find flights to Medellín Jose Maria Cordova Intl Airport for around $264 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Medellín Jose Maria Cordova Intl Airport from Guayaquil for as low as $239 on momondo.

What cabin class options are available on Guayaquil Jose Joaquin de Olmedo to Medellín Jose Maria Cordova Intl flights?

There is only 1 cabin class available to choose from on Guayaquil Jose Joaquin de Olmedo to Medellín Jose Maria Cordova Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Guayaquil to Medellín Jose Maria Cordova Intl Airport flight prices changed over time?

As of September 2025, prices for Guayaquil to Medellín Jose Maria Cordova Intl Airport flights are approximately 72% more expensive when compared to flights at the same time last year.

When to book flights from Guayaquil to Medellín Jose Maria Cordova Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Guayaquil to Medellín Jose Maria Cordova Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Guayaquil to Medellín Jose Maria Cordova Intl Airport (GYE to MDE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Guayaquil to Medellín Jose Maria Cordova Intl Airport

Best Price Found

$154

Fastest flight time

1h 40m

Direct flights

Tue, Thu and Sat
The best one-way flight to Medellín Jose Maria Cordova Intl Airport from Guayaquil in the past 72 hours is $154. The best round-trip flight deal from Guayaquil to Medellín Jose Maria Cordova Intl Airport found on momondo in the last 72 hours is $296.
The fastest flight from Guayaquil to Medellín Jose Maria Cordova Intl Airport takes 1h 40m
Direct flights go from Guayaquil to Medellín Jose Maria Cordova Intl Airport on Tuesday, Thursday and Saturday. The only airline offering direct flights is Avianca.
Search flight deals

  • How far is Guayaquil Jose Joaquin de Olmedo to Medellín Jose Maria Cordova Intl by plane?

    A flight from Guayaquil Jose Joaquin de Olmedo to Medellín Jose Maria Cordova Intl will travel around 654.1 mi. A reasonable flight in good conditions will take 1h 40m.

  • When did momondo last update prices for flights from Guayaquil Jose Joaquin de Olmedo Airport to Medellín Jose Maria Cordova Intl Airport?

    Prices for flights from Guayaquil Jose Joaquin de Olmedo Airport to Medellín Jose Maria Cordova Intl Airport are updated daily.

  • How many operators does momondo search for flights from Guayaquil Jose Joaquin de Olmedo Airport to Medellín Jose Maria Cordova Intl Airport?

  • How old do you have to be to fly from Guayaquil Jose Joaquin de Olmedo Airport to Medellín Jose Maria Cordova Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Guayaquil Jose Joaquin de Olmedo Airport to Medellín Jose Maria Cordova Intl Airport.

  • What documentation or ID do you need to fly to Medellín Jose Maria Cordova Intl Airport?

    The necessary travel and health documents for your Medellín Jose Maria Cordova Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Guayaquil to Medellín Jose Maria Cordova Intl Airport?

  • What is the most popular airline from Guayaquil to Medellín Jose Maria Cordova Intl Airport?

Best airlines flying from Guayaquil to Medellín Jose Maria Cordova Intl Airport

Compare and see reviews for airlines that fly from Guayaquil to Medellín Jose Maria Cordova Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $212Free CancellationRating
7.6
1,531 reviews
Search Copa Airlines flights
AviancaPriceFrom $223Free CancellationRating
6.7
2,435 reviews
Search Avianca flights

  • Avianca Flights From Guayaquil to Medellín Jose Maria Cordova Intl Airport

    Across 1 Avianca flight from Guayaquil to Medellín Jose Maria Cordova Intl Airport this week, the average price was $277, with the best Avianca deals starting from $223 round-trip. 2,435 users have rated Avianca on momondo, with an average score of 6.7/10.

Traveling to a place near Medellín?

Book flights to Medellín if you plan to visit one of these locations
Guatapé
Rionegro

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Why should I use momondo to find a flight deal from Guayaquil to Medellín?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Guayaquil to Medellín. momondo saves you time and could save you money on your trip.

Can I find flights from Guayaquil to Medellín with flexible booking policies on momondo?

Yes. All flights to Medellín from Guayaquil on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Guayaquil to Medellín?

Once all potential Guayaquil to Medellín flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Guayaquil to Medellín right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Guayaquil to Medellín now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Medellín and let you know when they change.

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