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Cheap flights from Greenville to Medellín from $259

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Medellín departing on 11/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
4:45 pm - 2:14 pmGSP-MDE
21h 29m1 stop
Multiple Airlines Logo
3:11 pm - 8:58 amMDE-GSP
17h 47m1 stop
$458Multiple Airlines
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Wed, Dec 31 - Sun, Jan 11
Multiple Airlines Logo
3:26 pm - 10:55 amGSP-MDE
19h 29m1 stop
Multiple Airlines Logo
12:09 pm - 3:59 pmMDE-GSP
27h 50m1 stop
$490Multiple Airlines
Find Deal
Tue, Dec 30 - Sun, Jan 11
Multiple Airlines Logo
4:43 pm - 2:14 pmGSP-MDE
45h 31m2 stops
Multiple Airlines Logo
3:11 pm - 8:58 amMDE-GSP
17h 47m1 stop
$516Multiple Airlines
Find Deal
Tue, Dec 30 - Sun, Jan 11
Multiple Airlines Logo
4:45 pm - 2:14 pmGSP-MDE
21h 29m1 stop
Multiple Airlines Logo
7:18 am - 8:58 amMDE-GSP
25h 40m2 stops
$522Multiple Airlines
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Wed, Dec 31 - Sun, Jan 11
United Airlines Logo
5:34 pm - 10:05 pmGSP-MDE
28h 31m2 stops
United Airlines Logo
10:45 am - 9:57 pmMDE-GSP
11h 12m1 stop
$531United Airlines
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Fri, Jan 23 - Sun, Feb 8
United Airlines Logo
4:50 pm - 10:05 pmGSP-MDE
29h 15m1 stop
United Airlines Logo
10:45 am - 9:57 pmMDE-GSP
11h 12m1 stop
$535United Airlines
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Fri, Jan 23 - Sun, Feb 8
United Airlines Logo
6:45 am - 10:05 pmGSP-MDE
15h 20m1 stop
United Airlines Logo
10:45 am - 9:58 pmMDE-GSP
11h 13m1 stop
$536United Airlines
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Sat, Nov 29 - Wed, Dec 17
American Airlines Logo
11:34 am - 11:39 pmGSP-MDE
12h 05m1 stop
American Airlines Logo
7:00 am - 11:59 pmMDE-GSP
16h 59m1 stop
$668American Airlines
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Wed, Nov 12 - Wed, Nov 19
American Airlines Logo
5:00 am - 9:10 pmGSP-MDE
16h 10m1 stop
American Airlines Logo
7:00 am - 10:31 pmMDE-GSP
15h 31m2 stops
$673American Airlines
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Wed, Nov 12 - Wed, Nov 19
LATAM Airlines Logo
11:12 am - 6:35 amGSP-MDE
19h 23m2 stops
LATAM Airlines Logo
5:30 am - 11:40 pmMDE-GSP
18h 10m2 stops
$712LATAM Airlines
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Tue, Nov 25 - Wed, Dec 10

United Airlines flights from Greenville to Medellín Jose Maria Cordova Intl Airport

Our best United Airlines deals on Greenville to Medellín Jose Maria Cordova Intl Airport flight tickets
United Airlines
Jan 23
GSP5:34 pmGreenville
28h 31m
2 stops
MDE10:05 pmMedellín Jose Maria Cordova Intl
Feb 8
MDE10:45 amMedellín Jose Maria Cordova Intl
11h 12m
1 stop
GSP9:57 pmGreenville
$531
Find similar
United Airlines
Jan 23
GSP4:50 pmGreenville
29h 15m
1 stop
MDE10:05 pmMedellín Jose Maria Cordova Intl
Feb 8
MDE10:45 amMedellín Jose Maria Cordova Intl
11h 12m
1 stop
GSP9:57 pmGreenville
$535
Find similar
United Airlines
Nov 29
GSP6:45 amGreenville
15h 20m
1 stop
MDE10:05 pmMedellín Jose Maria Cordova Intl
Dec 17
MDE10:45 amMedellín Jose Maria Cordova Intl
11h 13m
1 stop
GSP9:58 pmGreenville
$536
Find similar

American Airlines flights from Greenville to Medellín Jose Maria Cordova Intl Airport

Our best American Airlines deals on Greenville to Medellín Jose Maria Cordova Intl Airport flight tickets
American Airlines
Nov 12
GSP11:34 amGreenville
12h 05m
1 stop
MDE11:39 pmMedellín Jose Maria Cordova Intl
Nov 19
MDE7:00 amMedellín Jose Maria Cordova Intl
16h 59m
1 stop
GSP11:59 pmGreenville
$668
Find similar
American Airlines
Nov 12
GSP5:00 amGreenville
16h 10m
1 stop
MDE9:10 pmMedellín Jose Maria Cordova Intl
Nov 19
MDE7:00 amMedellín Jose Maria Cordova Intl
15h 31m
2 stops
GSP10:31 pmGreenville
$673
Find similar
American Airlines
Mar 10
GSP5:43 amGreenville
17h 32m
1 stop
MDE10:15 pmMedellín Jose Maria Cordova Intl
Mar 11
MDE12:20 amMedellín Jose Maria Cordova Intl
14h 21m
1 stop
GSP3:41 pmGreenville
$680
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to Medellín Jose Maria Cordova Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from Greenville to Medellín Jose Maria Cordova Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Wed 12/31

4:45 pm-2:14 pm

1 stop21h 29m

Medellín Jose Maria Cordova Intl

Sun 1/11

3:11 pm-8:58 am

1 stop17h 47m

$458

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Tue 12/30

3:26 pm-10:55 am

1 stop19h 29m

Medellín Jose Maria Cordova Intl

Sun 1/11

12:09 pm-3:59 pm

1 stop27h 50m

$490

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Tue 12/30

4:43 pm-2:14 pm

2 stops45h 31m

Medellín Jose Maria Cordova Intl

Sun 1/11

3:11 pm-8:58 am

1 stop17h 47m

$516

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Wed 12/31

4:45 pm-2:14 pm

1 stop21h 29m

Medellín Jose Maria Cordova Intl

Sun 1/11

7:18 am-8:58 am

2 stops25h 40m

$522

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 1/23

5:34 pm-10:05 pm

2 stops28h 31m

Medellín Jose Maria Cordova Intl

Sun 2/8

10:45 am-9:57 pm

1 stop11h 12m

$531

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 1/23

4:50 pm-10:05 pm

1 stop29h 15m

Medellín Jose Maria Cordova Intl

Sun 2/8

10:45 am-9:57 pm

1 stop11h 12m

$535

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sat 11/29

6:45 am-10:05 pm

1 stop15h 20m

Medellín Jose Maria Cordova Intl

Wed 12/17

10:45 am-9:58 pm

1 stop11h 13m

$536

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Wed 11/12

11:34 am-11:39 pm

1 stop12h 05m

Medellín Jose Maria Cordova Intl

Wed 11/19

7:00 am-11:59 pm

1 stop16h 59m

$668

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Wed 11/12

5:00 am-9:10 pm

1 stop16h 10m

Medellín Jose Maria Cordova Intl

Wed 11/19

7:00 am-10:31 pm

2 stops15h 31m

$673

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Tue 11/25

11:12 am-6:35 am

2 stops19h 23m

Medellín Jose Maria Cordova Intl

Wed 12/10

5:30 am-11:40 pm

2 stops18h 10m

$712

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Greenville to Medellín Jose Maria Cordova Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Medellín Jose Maria Cordova Intl Airport?

In general, February is the cheapest month to fly from Greenville to Medellín Jose Maria Cordova Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $634. If you aren’t able to travel during the month of February, then book flights to Medellín Jose Maria Cordova Intl Airport from Greenville during April instead. Flights to Medellín Jose Maria Cordova Intl Airport in April, while not as cheap as those in February, still average around $641.

What is the cheapest day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

The cheapest day to depart from Greenville to Medellín Jose Maria Cordova Intl Airport is on a Wednesday. Travelers who choose to depart for Medellín Jose Maria Cordova Intl Airport on a Wednesday will often find tickets for as low as $578. On the other hand, Sunday is the most expensive day to depart from Greenville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $959.

What is the cheapest time of day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

Our data shows that the cheapest Greenville to Medellín Jose Maria Cordova Intl Airport flights are usually those with departure times in the evening. Our users have found flights to Medellín Jose Maria Cordova Intl Airport in the evening for as low as $543. In contrast, the most expensive time of day to depart to Medellín Jose Maria Cordova Intl Airport is in the morning when prices are around $711.

How far in advance should I book a flight to Medellín Jose Maria Cordova Intl Airport?

You are more likely to see cheaper flights to Medellín Jose Maria Cordova Intl Airport from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to Medellín Jose Maria Cordova Intl Airport for around $738 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Medellín Jose Maria Cordova Intl Airport from Greenville for as low as $546 on momondo.

Can stopping save me money on Greenville to Medellín Jose Maria Cordova Intl Airport flights?

You could potentially save up to 36% on your flight if you consider stops on a Greenville to Medellín Jose Maria Cordova Intl Airport flight.

How have Greenville to Medellín Jose Maria Cordova Intl Airport flight prices changed over time?

When to book flights from Greenville to Medellín Jose Maria Cordova Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to Medellín Jose Maria Cordova Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to Medellín Jose Maria Cordova Intl Airport (GSP to MDE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Medellín Jose Maria Cordova Intl Airport

Direct flights

None
There are no direct flights from Greenville to Medellín Jose Maria Cordova Intl Airport. There are no popular flight routes from Greenville to Medellín Jose Maria Cordova Intl Airport.
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  • How far is Greenville to Medellín Jose Maria Cordova Intl by plane?

    Greenville and Medellín Jose Maria Cordova Intl are 2029.9 mi apart from one another. A reasonable flight in good conditions will take 8h 43m.

  • When did momondo last update prices for flights from Greenville Airport to Medellín Jose Maria Cordova Intl Airport?

    Prices for flights from Greenville Airport to Medellín Jose Maria Cordova Intl Airport are updated daily.

  • How many operators does momondo search for flights from Greenville Airport to Medellín Jose Maria Cordova Intl Airport?

  • How old do you have to be to fly from Greenville Airport to Medellín Jose Maria Cordova Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Medellín Jose Maria Cordova Intl Airport.

  • What documentation or ID do you need to fly to Medellín Jose Maria Cordova Intl Airport?

    The travel and health documents you'll need for your trip to Medellín Jose Maria Cordova Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Medellín Jose Maria Cordova Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to Medellín Jose Maria Cordova Intl Airport?

Best airlines flying from Greenville to Medellín Jose Maria Cordova Intl Airport

Compare and see reviews for airlines that fly from Greenville to Medellín Jose Maria Cordova Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $515Free CancellationRating
7.2
11,030 reviews
Search American Airlines flights

Traveling to a place near Medellín?

Book flights to Medellín if you plan to visit one of these locations
Guatapé
Rionegro

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Medellín?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Greenville to Medellín for you.

Can I find flights from Greenville to Medellín with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Medellín from Greenville with this policy.

How can momondo help me find flights from Greenville to Medellín?

momondo provides multiple filters to help you find the best flight to Medellín from Greenville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Greenville to Medellín right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Greenville to Medellín now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Medellín and let you know when they change.

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