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Cheap flights from Houston George Bush Intcntl Airport to Santiago from $293

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston George Bush Intcntl Airport to Santiago departing on 1/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Houston George Bush Intcntl Airport to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:30 am - 7:00 am
IAH
-
SCL
19h 30m1 stop
Multiple Airlines Logo
9:05 pm - 11:59 pm
SCL
-
IAH
29h 54m2 stops
$603Multiple Airlines
Wed, Jan 21 - Wed, Feb 25
Multiple Airlines Logo
8:30 am - 7:00 am
IAH
-
SCL
19h 30m1 stop
Multiple Airlines Logo
10:35 am - 9:13 am
SCL
-
IAH
25h 38m1 stop
$612Multiple Airlines
Wed, Jan 21 - Wed, Feb 25
Multiple Airlines Logo
5:05 am - 2:40 pm
IAH
-
SCL
30h 35m3 stops
Multiple Airlines Logo
9:05 pm - 5:56 pm
SCL
-
IAH
23h 51m2 stops
$651Multiple Airlines
Thu, Jan 29 - Thu, Feb 5
Multiple Airlines Logo
5:46 am - 2:40 pm
IAH
-
SCL
29h 54m2 stops
Multiple Airlines Logo
9:05 pm - 5:56 pm
SCL
-
IAH
23h 51m2 stops
$653Multiple Airlines
Thu, Jan 29 - Thu, Feb 5
Multiple Airlines Logo
5:05 am - 2:40 pm
IAH
-
SCL
30h 35m3 stops
Multiple Airlines Logo
9:05 pm - 5:56 pm
SCL
-
IAH
23h 51m2 stops
$669Multiple Airlines
Thu, Feb 5 - Wed, Feb 18
Multiple Airlines Logo
5:05 am - 2:40 pm
IAH
-
SCL
30h 35m3 stops
Multiple Airlines Logo
11:24 am - 8:40 am
SCL
-
IAH
24h 16m2 stops
$692Multiple Airlines
Thu, Feb 5 - Wed, Feb 18
Multiple Airlines Logo
5:05 am - 2:40 pm
IAH
-
SCL
30h 35m3 stops
Multiple Airlines Logo
3:45 pm - 5:56 pm
SCL
-
IAH
29h 11m3 stops
$699Multiple Airlines
Thu, Jan 29 - Thu, Feb 5
Multiple Airlines Logo
8:19 pm - 12:32 am
IAH
-
SCL
25h 13m2 stops
Multiple Airlines Logo
9:05 pm - 5:56 pm
SCL
-
IAH
23h 51m2 stops
$700Multiple Airlines
Mon, Feb 2 - Mon, Feb 16
Multiple Airlines Logo
3:09 pm - 10:15 pm
IAH
-
SCL
28h 06m3 stops
Multiple Airlines Logo
9:05 pm - 5:56 pm
SCL
-
IAH
23h 51m2 stops
$704Multiple Airlines
Mon, Jan 5 - Mon, Jan 26
Multiple Airlines Logo
5:05 am - 2:40 pm
IAH
-
SCL
30h 35m3 stops
Multiple Airlines Logo
11:24 am - 2:24 pm
SCL
-
IAH
30h 00m3 stops
$720Multiple Airlines
Thu, Feb 5 - Wed, Feb 18

Avianca flights from Houston George Bush Intcntl Airport to Santiago

Our best Avianca deals on Houston George Bush Intcntl Airport to Santiago flight tickets
Avianca
Mar 5
IAH1:00 pmHouston George Bush Intcntl
32h 30m
2 stops
SCL12:30 amSantiago Arturo Merino Benitez
Mar 14
SCL4:25 pmSantiago Arturo Merino Benitez
25h 45m
2 stops
IAH4:10 pmHouston George Bush Intcntl
$903
Find similar
Avianca
Feb 5
IAH1:00 pmHouston George Bush Intcntl
23h 20m
2 stops
SCL3:20 pmSantiago Arturo Merino Benitez
Feb 18
SCL4:25 pmSantiago Arturo Merino Benitez
21h 40m
2 stops
IAH11:05 amHouston George Bush Intcntl
$950
Find similar
Avianca
Dec 23
IAH1:00 pmHouston George Bush Intcntl
32h 30m
2 stops
SCL12:30 amSantiago Arturo Merino Benitez
Dec 27
SCL1:35 amSantiago Arturo Merino Benitez
16h 35m
2 stops
IAH3:10 pmHouston George Bush Intcntl
$1,013
Find similar

American Airlines flights from Houston George Bush Intcntl Airport to Santiago

Our best American Airlines deals on Houston George Bush Intcntl Airport to Santiago flight tickets
American Airlines
Feb 2
IAH2:41 pmHouston George Bush Intcntl
15h 19m
2 stops
SCL9:00 amSantiago Arturo Merino Benitez
Feb 16
SCL10:00 pmSantiago Arturo Merino Benitez
16h 31m
1 stop
IAH11:31 amHouston George Bush Intcntl
$958
Find similar
American Airlines
Mar 25
IAH2:08 pmHouston George Bush Intcntl
14h 42m
1 stop
SCL6:50 amSantiago Arturo Merino Benitez
Apr 7
SCL8:50 pmSantiago Arturo Merino Benitez
21h 37m
1 stop
IAH5:27 pmHouston George Bush Intcntl
$964
Find similar
American Airlines
Dec 22
IAH7:15 amHouston George Bush Intcntl
23h 10m
1 stop
SCL9:25 amSantiago Arturo Merino Benitez
Jan 12
SCL10:35 pmSantiago Arturo Merino Benitez
14h 53m
1 stop
IAH10:28 amHouston George Bush Intcntl
$1,985
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Houston George Bush Intcntl Airport to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Houston George Bush Intcntl Airport to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Wed 1/21

8:30 am-7:00 am

1 stop19h 30m

Santiago Arturo Merino Benitez

Wed 2/25

9:05 pm-11:59 pm

2 stops29h 54m

$603

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Wed 1/21

8:30 am-7:00 am

1 stop19h 30m

Santiago Arturo Merino Benitez

Wed 2/25

10:35 am-9:13 am

1 stop25h 38m

$612

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Thu 1/29

5:05 am-2:40 pm

3 stops30h 35m

Santiago Arturo Merino Benitez

Thu 2/5

9:05 pm-5:56 pm

2 stops23h 51m

$651

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Thu 1/29

5:46 am-2:40 pm

2 stops29h 54m

Santiago Arturo Merino Benitez

Thu 2/5

9:05 pm-5:56 pm

2 stops23h 51m

$653

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Thu 2/5

5:05 am-2:40 pm

3 stops30h 35m

Santiago Arturo Merino Benitez

Wed 2/18

9:05 pm-5:56 pm

2 stops23h 51m

$669

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Thu 2/5

5:05 am-2:40 pm

3 stops30h 35m

Santiago Arturo Merino Benitez

Wed 2/18

11:24 am-8:40 am

2 stops24h 16m

$692

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Thu 1/29

5:05 am-2:40 pm

3 stops30h 35m

Santiago Arturo Merino Benitez

Thu 2/5

3:45 pm-5:56 pm

3 stops29h 11m

$699

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Mon 2/2

8:19 pm-12:32 am

2 stops25h 13m

Santiago Arturo Merino Benitez

Mon 2/16

9:05 pm-5:56 pm

2 stops23h 51m

$700

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Mon 1/5

3:09 pm-10:15 pm

3 stops28h 06m

Santiago Arturo Merino Benitez

Mon 1/26

9:05 pm-5:56 pm

2 stops23h 51m

$704

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Thu 2/5

5:05 am-2:40 pm

3 stops30h 35m

Santiago Arturo Merino Benitez

Wed 2/18

11:24 am-2:24 pm

3 stops30h 00m

$720

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Houston George Bush Intcntl Airport to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Houston George Bush Intcntl Airport and Santiago?

What is the cheapest month to fly to Santiago?

In general, May is the cheapest month to fly from Houston George Bush Intcntl Airport to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $631. If you don’t want to visit Santiago in May, then you should wait until October to fly from Houston George Bush Intcntl Airport, when ticket prices are also cheap, with an average price of $812.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $1,037. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Sunday is $1,557.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from Houston George Bush Intcntl Airport to Santiago when you can find flight prices for as low as $981. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,435 per ticket.

What is the cheapest Houston George Bush Intcntl to Santiago Arturo Merino Benitez flight route?

Fly from Houston George Bush Intcntl to Santiago Arturo Merino Benitez for the best Houston George Bush Intcntl - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Houston George Bush Intcntl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $1,236 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Houston George Bush Intcntl Airport for as low as $668 on momondo.

What cabin class options are available on Houston George Bush Intcntl to Santiago Arturo Merino Benitez flights?

There are 3 cabin classes available to choose from on Houston George Bush Intcntl to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Houston George Bush Intcntl Airport to Santiago flights?

You could potentially save up to 70% on your flight if you consider stops on a Houston George Bush Intcntl Airport to Santiago flight.

How have Houston George Bush Intcntl Airport to Santiago flight prices changed over time?

As of December 2025, prices for Houston George Bush Intcntl Airport to Santiago flights are approximately 56% cheaper when compared to flights at the same time last year.

When to book flights from Houston George Bush Intcntl Airport to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Houston George Bush Intcntl Airport to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Houston George Bush Intcntl Airport to Santiago (IAH to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston George Bush Intcntl Airport to Santiago

Best Price Found

$677

Fastest flight time

9h 05m

Direct flights

Mon, Tue, Thu, Fri, Sat and Sun

Airports in Santiago

1 airport
The best one-way flight to Santiago from Houston George Bush Intcntl Airport in the past 72 hours is $677. The best round-trip flight deal from Houston George Bush Intcntl Airport to Santiago found on momondo in the last 72 hours is $1,149.
The fastest flight from Houston George Bush Intcntl Airport to Santiago takes 9h 05m
Direct flights go from Houston George Bush Intcntl Airport to Santiago on Monday, Tuesday, Thursday, Friday, Saturday and Sunday. The only airline offering direct flights is United Airlines.
There is 1 airport in Santiago. From Houston George Bush Intcntl Airport there are direct flights to Santiago Arturo Merino Benitez (SCL).
Search flight deals

  • How far is Houston George Bush Intcntl to Santiago Arturo Merino Benitez by plane?

    Houston George Bush Intcntl and Santiago Arturo Merino Benitez are 4667.0 mi apart from one another. 9h 05m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Houston George Bush Intcntl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Houston George Bush Intcntl Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Houston George Bush Intcntl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Houston George Bush Intcntl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston George Bush Intcntl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Houston George Bush Intcntl Airport to Santiago?

  • What is the most popular airline from Houston George Bush Intcntl Airport to Santiago?

Best airlines flying from Houston George Bush Intcntl Airport to Santiago

Compare and see reviews for airlines that fly from Houston George Bush Intcntl Airport to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $548Free CancellationRating
6.6
2,484 reviews
Search Avianca flights
DeltaPriceFrom $963Free CancellationRating
7.9
8,010 reviews
Search Delta flights
LATAM AirlinesPriceFrom $963Free CancellationRating
7.5
1,891 reviews
Search LATAM Airlines flights
United AirlinesPriceFrom $989Free CancellationRating
7.4
9,094 reviews
Search United Airlines flights
American AirlinesPriceFrom $1,242Free CancellationRating
7.2
11,049 reviews
Search American Airlines flights

  • United Airlines Flights From Houston George Bush Intcntl Airport to Santiago

    United Airlines operates around 7 flights from Houston George Bush Intcntl Airport to Santiago every week. The average price of these flights found in the last 72 hours has been $1,425, but momondo users have found United Airlines deals from Houston George Bush Intcntl Airport to Santiago from as low as $989 round-trip. United Airlines has been scored 7.4/10 in 9,094 reviews.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Houston to Santiago for you.

Can I find flights from Houston to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Houston to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from Houston to Santiago?

momondo helps you find the best flight between Houston and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Houston to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Houston to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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