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Cheap flights from Houston George Bush Intcntl Airport to Santiago from $261

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston George Bush Intcntl Airport to Santiago departing on 3/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Houston George Bush Intcntl Airport to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:24 pm - 10:15 pm
IAH
-
SCL
26h 51m
2 stops
Multiple Airlines Logo
7:15 am - 11:49 pm
SCL
-
IAH
18h 34m
2 stops
$580Multiple Airlines
mié., mar. 18 - mar., mar. 24
Multiple Airlines Logo
5:24 pm - 10:15 pm
IAH
-
SCL
26h 51m
2 stops
Multiple Airlines Logo
8:15 am - 11:49 pm
SCL
-
IAH
17h 34m
1 stop
$581Multiple Airlines
mar., mar. 17 - lun., mar. 23
Multiple Airlines Logo
5:24 pm - 10:15 pm
IAH
-
SCL
26h 51m
2 stops
Multiple Airlines Logo
8:15 am - 11:49 pm
SCL
-
IAH
17h 34m
1 stop
$583Multiple Airlines
lun., mar. 16 - lun., mar. 23
Multiple Airlines Logo
2:39 pm - 9:15 pm
IAH
-
SCL
29h 36m
2 stops
Multiple Airlines Logo
11:00 pm - 11:51 pm
SCL
-
IAH
25h 51m
1 stop
$584Multiple Airlines
dom., may. 17 - mar., may. 26
Multiple Airlines Logo
5:24 pm - 10:15 pm
IAH
-
SCL
26h 51m
2 stops
Multiple Airlines Logo
8:15 am - 11:49 pm
SCL
-
IAH
17h 34m
1 stop
$598Multiple Airlines
jue., mar. 19 - lun., mar. 23
Multiple Airlines Logo
5:23 pm - 2:35 am
IAH
-
SCL
32h 12m
2 stops
Multiple Airlines Logo
11:00 pm - 11:51 pm
SCL
-
IAH
25h 51m
1 stop
$601Multiple Airlines
mié., abr. 29 - lun., may. 11
Multiple Airlines Logo
5:15 am - 2:40 pm
IAH
-
SCL
31h 25m
3 stops
Multiple Airlines Logo
9:05 pm - 11:49 pm
SCL
-
IAH
28h 44m
2 stops
$604Multiple Airlines
dom., mar. 15 - dom., mar. 22
Multiple Airlines Logo
5:23 pm - 2:35 am
IAH
-
SCL
32h 12m
2 stops
Multiple Airlines Logo
10:30 am - 11:51 pm
SCL
-
IAH
14h 21m
1 stop
$605Multiple Airlines
lun., abr. 20 - mar., abr. 28
Multiple Airlines Logo
9:24 am - 5:40 am
IAH
-
SCL
19h 16m
2 stops
Multiple Airlines Logo
8:30 am - 8:19 am
SCL
-
IAH
24h 49m
2 stops
$612Multiple Airlines
mar., may. 19 - mar., may. 26
Multiple Airlines Logo
5:24 pm - 12:30 am
IAH
-
SCL
29h 06m
2 stops
Multiple Airlines Logo
7:15 am - 11:49 pm
SCL
-
IAH
18h 34m
2 stops
$616Multiple Airlines
mar., mar. 10 - mar., mar. 17

Avianca flights from Houston George Bush Intcntl Airport to Santiago

Our best Avianca deals on Houston George Bush Intcntl Airport to Santiago flight tickets
Avianca
May 29
IAH2:05 pmHouston George Bush Intcntl
23h 10m
3 stops
SCL2:15 pmSantiago Arturo Merino Benitez
Jun 17
SCL6:10 amSantiago Arturo Merino Benitez
30h 55m
2 stops
IAH12:05 pmHouston George Bush Intcntl
$750
Avianca
Feb 3
IAH1:00 pmHouston George Bush Intcntl
32h 30m
2 stops
SCL12:30 amSantiago Arturo Merino Benitez
Feb 28
SCL4:25 pmSantiago Arturo Merino Benitez
25h 45m
2 stops
IAH3:10 pmHouston George Bush Intcntl
$869
Avianca
Feb 8
IAH4:35 pmHouston George Bush Intcntl
28h 55m
2 stops
SCL12:30 amSantiago Arturo Merino Benitez
Feb 10
SCL1:35 amSantiago Arturo Merino Benitez
16h 35m
2 stops
IAH3:10 pmHouston George Bush Intcntl
$900

United Airlines flights from Houston George Bush Intcntl Airport to Santiago

Our best United Airlines deals on Houston George Bush Intcntl Airport to Santiago flight tickets
United Airlines
Feb 3
IAH8:45 pmHouston George Bush Intcntl
9h 05m
SCL8:50 amSantiago Arturo Merino Benitez
Feb 28
SCL10:45 pmSantiago Arturo Merino Benitez
9h 20m
IAH5:05 amHouston George Bush Intcntl
$1,926
United Airlines
Feb 8
IAH8:45 pmHouston George Bush Intcntl
9h 05m
SCL8:50 amSantiago Arturo Merino Benitez
Feb 16
SCL10:45 pmSantiago Arturo Merino Benitez
9h 20m
IAH5:05 amHouston George Bush Intcntl
$2,261
United Airlines
Feb 6
IAH8:45 pmHouston George Bush Intcntl
9h 05m
SCL8:50 amSantiago Arturo Merino Benitez
Feb 13
SCL10:45 pmSantiago Arturo Merino Benitez
9h 20m
IAH5:05 amHouston George Bush Intcntl
$2,301

momondo Fare Finder

 
Customize your flight search to find flights from Houston George Bush Intcntl Airport to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated enero 29, 2026.
Use the filters below to find and compare flights from Houston George Bush Intcntl Airport to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

mié. 3/18

5:24 pm-10:15 pm

2 stops26h 51m

Santiago Arturo Merino Benitez

mar. 3/24

7:15 am-11:49 pm

2 stops18h 34m

$580

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

mar. 3/17

5:24 pm-10:15 pm

2 stops26h 51m

Santiago Arturo Merino Benitez

lun. 3/23

8:15 am-11:49 pm

1 stop17h 34m

$581

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

lun. 3/16

5:24 pm-10:15 pm

2 stops26h 51m

Santiago Arturo Merino Benitez

lun. 3/23

8:15 am-11:49 pm

1 stop17h 34m

$583

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

dom. 5/17

2:39 pm-9:15 pm

2 stops29h 36m

Santiago Arturo Merino Benitez

mar. 5/26

11:00 pm-11:51 pm

1 stop25h 51m

$584

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

jue. 3/19

5:24 pm-10:15 pm

2 stops26h 51m

Santiago Arturo Merino Benitez

lun. 3/23

8:15 am-11:49 pm

1 stop17h 34m

$598

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

mié. 4/29

5:23 pm-2:35 am

2 stops32h 12m

Santiago Arturo Merino Benitez

lun. 5/11

11:00 pm-11:51 pm

1 stop25h 51m

$601

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

dom. 3/15

5:15 am-2:40 pm

3 stops31h 25m

Santiago Arturo Merino Benitez

dom. 3/22

9:05 pm-11:49 pm

2 stops28h 44m

$604

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

lun. 4/20

5:23 pm-2:35 am

2 stops32h 12m

Santiago Arturo Merino Benitez

mar. 4/28

10:30 am-11:51 pm

1 stop14h 21m

$605

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

mar. 5/19

9:24 am-5:40 am

2 stops19h 16m

Santiago Arturo Merino Benitez

mar. 5/26

8:30 am-8:19 am

2 stops24h 49m

$612

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

mar. 3/10

5:24 pm-12:30 am

2 stops29h 06m

Santiago Arturo Merino Benitez

mar. 3/17

7:15 am-11:49 pm

2 stops18h 34m

$616

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Houston George Bush Intcntl Airport to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Houston George Bush Intcntl Airport and Santiago?

What is the cheapest month to fly to Santiago?

In general, May is the cheapest month to fly from Houston George Bush Intcntl Airport to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $624. If you don’t want to visit Santiago in May, then you should wait until October to fly from Houston George Bush Intcntl Airport, when ticket prices are also cheap, with an average price of $812.

What is the cheapest Houston George Bush Intcntl to Santiago Arturo Merino Benitez flight route?

Fly from Houston George Bush Intcntl to Santiago Arturo Merino Benitez for the best Houston George Bush Intcntl - Santiago Arturo Merino Benitez flight prices

What cabin class options are available on Houston George Bush Intcntl to Santiago Arturo Merino Benitez flights?

There are 3 cabin classes available to choose from on Houston George Bush Intcntl to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Houston George Bush Intcntl Airport to Santiago flights?

You could potentially save up to 71% on your flight if you consider stops on a Houston George Bush Intcntl Airport to Santiago flight.

How have Houston George Bush Intcntl Airport to Santiago flight prices changed over time?

As of January 2026, prices for Houston George Bush Intcntl Airport to Santiago flights are approximately 323% more expensive when compared to flights at the same time last year.

When to book flights from Houston George Bush Intcntl Airport to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Houston George Bush Intcntl Airport to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Houston George Bush Intcntl Airport to Santiago (IAH to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston George Bush Intcntl Airport to Santiago

Best Price Found

$1,123

Fastest flight time

9h 05m

Direct flights

Mon, Tue, Wed, Thu, Fri and Sun

Airports in Santiago

1 airport
The best one-way flight to Santiago from Houston George Bush Intcntl Airport in the past 72 hours is $1,123. The best round-trip flight deal from Houston George Bush Intcntl Airport to Santiago found on momondo in the last 72 hours is $1,010.
The fastest flight from Houston George Bush Intcntl Airport to Santiago takes 9h 05m
Direct flights go from Houston George Bush Intcntl Airport to Santiago on Monday, Tuesday, Wednesday, Thursday, Friday and Sunday. The only airline offering direct flights is United Airlines.
There is 1 airport in Santiago. From Houston George Bush Intcntl Airport there are direct flights to Santiago Arturo Merino Benitez (SCL).
Search flight deals

  • How far is Houston George Bush Intcntl to Santiago Arturo Merino Benitez by plane?

    Houston George Bush Intcntl and Santiago Arturo Merino Benitez are 4667.0 mi apart from one another. 9h 05m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Houston George Bush Intcntl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Houston George Bush Intcntl Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Houston George Bush Intcntl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Houston George Bush Intcntl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston George Bush Intcntl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Houston George Bush Intcntl Airport to Santiago?

  • What is the most popular airline from Houston George Bush Intcntl Airport to Santiago?

Best airlines flying from Houston George Bush Intcntl Airport to Santiago

Compare and see reviews for airlines that fly from Houston George Bush Intcntl Airport to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $548Free CancellationRating
6.6
2,490 reviews
Search Avianca flights
LATAM AirlinesPriceFrom $963Free CancellationRating
7.5
1,917 reviews
Search LATAM Airlines flights
United AirlinesPriceFrom $989Free CancellationRating
7.4
9,216 reviews
Search United Airlines flights
American AirlinesPriceFrom $1,203Free CancellationRating
7.2
11,206 reviews
Search American Airlines flights

  • United Airlines Flights From Houston George Bush Intcntl Airport to Santiago

    United Airlines operates around 7 flights from Houston George Bush Intcntl Airport to Santiago every week. The average price of these flights found in the last 72 hours has been $1,254, but momondo users have found United Airlines deals from Houston George Bush Intcntl Airport to Santiago from as low as $989 round-trip. United Airlines has been scored 7.4/10 in 9,216 reviews.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Houston to Santiago for you.

Can I find flights from Houston to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Houston to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from Houston to Santiago?

momondo helps you find the best flight between Houston and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

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Of course. momondo tracks the price of Houston to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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