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Cheap flights from Houston George Bush Intcntl Airport to Santiago from $251

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston George Bush Intcntl Airport to Santiago departing on 12/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Houston George Bush Intcntl Airport to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:35 pm - 10:15 pmIAH-SCL
22h 40m2 stops
Multiple Airlines Logo
9:05 pm - 7:30 pmSCL-IAH
25h 25m2 stops
$538Multiple Airlines
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mié., nov. 12 - lun., nov. 17
Multiple Airlines Logo
8:10 pm - 5:50 amIAH-SCL
30h 40m2 stops
Multiple Airlines Logo
9:10 pm - 7:05 pmSCL-IAH
24h 55m2 stops
$559Multiple Airlines
Find Deal
sáb., nov. 22 - mar., dic. 2
Multiple Airlines Logo
8:35 pm - 5:50 amIAH-SCL
30h 15m2 stops
Multiple Airlines Logo
5:50 am - 2:18 pmSCL-IAH
35h 28m2 stops
$560Multiple Airlines
Find Deal
dom., nov. 9 - jue., nov. 13
Multiple Airlines Logo
8:35 pm - 5:50 amIAH-SCL
30h 15m2 stops
Multiple Airlines Logo
9:05 pm - 9:47 pmSCL-IAH
27h 42m3 stops
$566Multiple Airlines
Find Deal
mié., nov. 12 - lun., nov. 17
Multiple Airlines Logo
11:10 pm - 10:15 pmIAH-SCL
44h 05m3 stops
Multiple Airlines Logo
12:30 pm - 7:30 pmSCL-IAH
34h 00m2 stops
$568Multiple Airlines
Find Deal
dom., nov. 9 - vie., nov. 14
Multiple Airlines Logo
11:10 pm - 2:40 pmIAH-SCL
36h 30m3 stops
Multiple Airlines Logo
5:50 am - 2:18 pmSCL-IAH
35h 28m2 stops
$572Multiple Airlines
Find Deal
dom., nov. 9 - jue., nov. 13
Multiple Airlines Logo
8:35 pm - 2:40 pmIAH-SCL
39h 05m2 stops
Multiple Airlines Logo
11:25 pm - 10:07 amSCL-IAH
13h 42m1 stop
$574Multiple Airlines
Find Deal
dom., nov. 9 - vie., nov. 14
Multiple Airlines Logo
8:35 pm - 5:50 amIAH-SCL
30h 15m2 stops
Multiple Airlines Logo
9:05 pm - 7:30 pmSCL-IAH
25h 25m2 stops
$578Multiple Airlines
Find Deal
dom., nov. 9 - vie., nov. 14
Air Canada Logo
11:50 am - 12:15 pmIAH-SCL
21h 25m2 stops
Air Canada Logo
8:55 pm - 9:39 pmSCL-IAH
27h 44m2 stops
$698Air Canada
Find Deal
lun., feb. 2 - mar., feb. 17
Air Canada Logo
11:55 am - 12:15 pmIAH-SCL
21h 20m1 stop
Air Canada Logo
8:55 pm - 6:38 pmSCL-IAH
24h 43m1 stop
$701Air Canada
Find Deal
lun., nov. 17 - lun., nov. 24

Air Canada flights from Houston George Bush Intcntl Airport to Santiago

Our best Air Canada deals on Houston George Bush Intcntl Airport to Santiago flight tickets
Air Canada
Feb 2
IAH11:50 amHouston George Bush Intcntl
21h 25m
2 stops
SCL12:15 pmSantiago Arturo Merino Benitez
Feb 17
SCL8:55 pmSantiago Arturo Merino Benitez
27h 44m
2 stops
IAH9:39 pmHouston George Bush Intcntl
$698
Find similar
Air Canada
Nov 17
IAH11:55 amHouston George Bush Intcntl
21h 20m
1 stop
SCL12:15 pmSantiago Arturo Merino Benitez
Nov 24
SCL8:55 pmSantiago Arturo Merino Benitez
24h 43m
1 stop
IAH6:38 pmHouston George Bush Intcntl
$701
Find similar

United Airlines flights from Houston George Bush Intcntl Airport to Santiago

Our best United Airlines deals on Houston George Bush Intcntl Airport to Santiago flight tickets
United Airlines
Nov 1
IAH8:45 pmHouston George Bush Intcntl
9h 05m
SCL7:50 amSantiago Arturo Merino Benitez
Nov 7
SCL10:45 pmSantiago Arturo Merino Benitez
9h 20m
IAH5:05 amHouston George Bush Intcntl
$2,280
Find similar
United Airlines
Oct 29
IAH8:45 pmHouston George Bush Intcntl
9h 05m
SCL7:50 amSantiago Arturo Merino Benitez
Nov 11
SCL10:45 pmSantiago Arturo Merino Benitez
9h 20m
IAH5:05 amHouston George Bush Intcntl
$4,190
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Houston George Bush Intcntl Airport to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated octubre 22, 2025.
Use the filters below to find and compare flights from Houston George Bush Intcntl Airport to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

mié. 11/12

8:35 pm-10:15 pm

2 stops22h 40m

Santiago Arturo Merino Benitez

lun. 11/17

9:05 pm-7:30 pm

2 stops25h 25m

$538

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

sáb. 11/22

8:10 pm-5:50 am

2 stops30h 40m

Santiago Arturo Merino Benitez

mar. 12/2

9:10 pm-7:05 pm

2 stops24h 55m

$559

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

dom. 11/9

8:35 pm-5:50 am

2 stops30h 15m

Santiago Arturo Merino Benitez

jue. 11/13

5:50 am-2:18 pm

2 stops35h 28m

$560

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

mié. 11/12

8:35 pm-5:50 am

2 stops30h 15m

Santiago Arturo Merino Benitez

lun. 11/17

9:05 pm-9:47 pm

3 stops27h 42m

$566

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

dom. 11/9

11:10 pm-10:15 pm

3 stops44h 05m

Santiago Arturo Merino Benitez

vie. 11/14

12:30 pm-7:30 pm

2 stops34h 00m

$568

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

dom. 11/9

11:10 pm-2:40 pm

3 stops36h 30m

Santiago Arturo Merino Benitez

jue. 11/13

5:50 am-2:18 pm

2 stops35h 28m

$572

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

dom. 11/9

8:35 pm-2:40 pm

2 stops39h 05m

Santiago Arturo Merino Benitez

vie. 11/14

11:25 pm-10:07 am

1 stop13h 42m

$574

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

dom. 11/9

8:35 pm-5:50 am

2 stops30h 15m

Santiago Arturo Merino Benitez

vie. 11/14

9:05 pm-7:30 pm

2 stops25h 25m

$578

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

lun. 2/2

11:50 am-12:15 pm

2 stops21h 25m

Santiago Arturo Merino Benitez

mar. 2/17

8:55 pm-9:39 pm

2 stops27h 44m

$698

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

lun. 11/17

11:55 am-12:15 pm

1 stop21h 20m

Santiago Arturo Merino Benitez

lun. 11/24

8:55 pm-6:38 pm

1 stop24h 43m

$701

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Houston George Bush Intcntl Airport to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, May is the cheapest month to fly from Houston George Bush Intcntl Airport to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $657. If you don’t want to visit Santiago in May, then you should wait until October to fly from Houston George Bush Intcntl Airport, when ticket prices are also cheap, with an average price of $675.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $1,037. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Sunday is $1,557.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from Houston George Bush Intcntl Airport to Santiago when you can find flight prices for as low as $981. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,500 per ticket.

What is the cheapest Houston George Bush Intcntl to Santiago Arturo Merino Benitez flight route?

Fly from Houston George Bush Intcntl to Santiago Arturo Merino Benitez for the best Houston George Bush Intcntl - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Houston George Bush Intcntl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $1,281 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Houston George Bush Intcntl Airport for as low as $668 on momondo.

What cabin class options are available on Houston George Bush Intcntl to Santiago Arturo Merino Benitez flights?

There are 3 cabin classes available to choose from on Houston George Bush Intcntl to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Houston George Bush Intcntl Airport to Santiago flights?

You could potentially save up to 58% on your flight if you consider stops on a Houston George Bush Intcntl Airport to Santiago flight.

How have Houston George Bush Intcntl Airport to Santiago flight prices changed over time?

As of October 2025, prices for Houston George Bush Intcntl Airport to Santiago flights are approximately 758% more expensive when compared to flights at the same time last year.

When to book flights from Houston George Bush Intcntl Airport to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Houston George Bush Intcntl Airport to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Houston George Bush Intcntl Airport to Santiago (IAH to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston George Bush Intcntl Airport to Santiago

Best Price Found

$949

Fastest flight time

9h 05m

Direct flights

Every day

Airports in Santiago

1 airport
The best flight deal from Houston George Bush Intcntl Airport to Santiago found on momondo in the last 72 hours is $949
The fastest flight from Houston George Bush Intcntl Airport to Santiago takes 9h 05m
Direct flights go from Houston George Bush Intcntl Airport to Santiago every day.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)
Search flight deals

  • How far is Houston George Bush Intcntl to Santiago Arturo Merino Benitez by plane?

    Houston George Bush Intcntl and Santiago Arturo Merino Benitez are 4667.0 mi apart from one another. 21h 20m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Houston George Bush Intcntl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Houston George Bush Intcntl Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Houston George Bush Intcntl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Houston George Bush Intcntl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston George Bush Intcntl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents you'll need for your trip to Santiago Arturo Merino Benitez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Houston George Bush Intcntl Airport to Santiago?

  • What is the most popular airline from Houston George Bush Intcntl Airport to Santiago?

Best airlines flying from Houston George Bush Intcntl Airport to Santiago

Compare and see reviews for airlines that fly from Houston George Bush Intcntl Airport to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $548Free CancellationRating
6.6
2,456 reviews
Search Avianca flights
DeltaPriceFrom $963Free CancellationRating
7.9
7,979 reviews
Search Delta flights
LATAM AirlinesPriceFrom $963Free CancellationRating
7.5
1,869 reviews
Search LATAM Airlines flights
United AirlinesPriceFrom $989Free CancellationRating
7.4
8,988 reviews
Search United Airlines flights
American AirlinesPriceFrom $1,242Free CancellationRating
7.2
11,028 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Houston to Santiago for you.

Can I find flights from Houston to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Houston to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from Houston to Santiago?

momondo helps you find the best flight between Houston and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Houston to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Houston to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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